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Improved methods,properties,applications and prospects of microbial induced carbonate precipitation(MICP)treated soil:A review 被引量:2
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作者 Xuanshuo Zhang Hongyu Wang +3 位作者 Ya Wang Jinghui Wang Jing Cao Gang Zhang 《Biogeotechnics》 2025年第1期34-54,共21页
Soil improvement is one of the most important issues in geotechnical engineering practice.The wide application of traditional improvement techniques(cement/chemical materials)are limited due to damage ecological en-vi... Soil improvement is one of the most important issues in geotechnical engineering practice.The wide application of traditional improvement techniques(cement/chemical materials)are limited due to damage ecological en-vironment and intensify carbon emissions.However,the use of microbially induced calcium carbonate pre-cipitation(MICP)to obtain bio-cement is a novel technique with the potential to induce soil stability,providing a low-carbon,environment-friendly,and sustainable integrated solution for some geotechnical engineering pro-blems in the environment.This paper presents a comprehensive review of the latest progress in soil improvement based on the MICP strategy.It systematically summarizes and overviews the mineralization mechanism,influ-encing factors,improved methods,engineering characteristics,and current field application status of the MICP.Additionally,it also explores the limitations and correspondingly proposes prospective applications via the MICP approach for soil improvement.This review indicates that the utilization of different environmental calcium-based wastes in MICP and combination of materials and MICP are conducive to meeting engineering and market demand.Furthermore,we recommend and encourage global collaborative study and practice with a view to commercializing MICP technique in the future.The current review purports to provide insights for engineers and interdisciplinary researchers,and guidance for future engineering applications. 展开更多
关键词 Soil improvement Bio-cement MICP Improved methods Field application cases
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Insight Into the Separation-of-Variable Methods for the Closed-Form Solutions of Free Vibration of Rectangular Thin Plates
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作者 Yufeng Xing Ye Yuan Gen Li 《Computer Modeling in Engineering & Sciences》 SCIE EI 2025年第1期329-355,共27页
The separation-of-variable(SOV)methods,such as the improved SOV method,the variational SOV method,and the extended SOV method,have been proposed by the present authors and coworkers to obtain the closed-form analytica... The separation-of-variable(SOV)methods,such as the improved SOV method,the variational SOV method,and the extended SOV method,have been proposed by the present authors and coworkers to obtain the closed-form analytical solutions for free vibration and eigenbuckling of rectangular plates and circular cylindrical shells.By taking the free vibration of rectangular thin plates as an example,this work presents the theoretical framework of the SOV methods in an instructive way,and the bisection–based solution procedures for a group of nonlinear eigenvalue equations.Besides,the explicit equations of nodal lines of the SOV methods are presented,and the relations of nodal line patterns and frequency orders are investigated.It is concluded that the highly accurate SOV methods have the same accuracy for all frequencies,the mode shapes about repeated frequencies can also be precisely captured,and the SOV methods do not have the problem of missing roots as well. 展开更多
关键词 Separation-of-variable method Rayleigh quotient nodal line eigenvalue equation bisection method
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A Review of the Hydrodynamic Damping Characteristics of Blade-like Structures:Focus on the Quantitative Identification Methods and Key Influencing Parameters 被引量:1
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作者 Yongshun Zeng Zhaohui Qian +1 位作者 Jiayun Zhang Zhifeng Yao 《哈尔滨工程大学学报(英文版)》 2025年第1期21-34,共14页
Ocean energy has progressively gained considerable interest due to its sufficient potential to meet the world’s energy demand,and the blade is the core component in electricity generation from the ocean current.Howev... Ocean energy has progressively gained considerable interest due to its sufficient potential to meet the world’s energy demand,and the blade is the core component in electricity generation from the ocean current.However,the widened hydraulic excitation frequency may satisfy the blade resonance due to the time variation in the velocity and angle of attack of the ocean current,even resulting in blade fatigue and destructively interfering with grid stability.A key parameter that determines the resonance amplitude of the blade is the hydrodynamic damping ratio(HDR).However,HDR is difficult to obtain due to the complex fluid-structure interaction(FSI).Therefore,a literature review was conducted on the hydrodynamic damping characteristics of blade-like structures.The experimental and simulation methods used to identify and obtain the HDR quantitatively were described,placing emphasis on the experimental processes and simulation setups.Moreover,the accuracy and efficiency of different simulation methods were compared,and the modal work approach was recommended.The effects of key typical parameters,including flow velocity,angle of attack,gap,rotational speed,and cavitation,on the HDR were then summarized,and the suggestions on operating conditions were presented from the perspective of increasing the HDR.Subsequently,considering multiple flow parameters,several theoretical derivations and semi-empirical prediction formulas for HDR were introduced,and the accuracy and application were discussed.Based on the shortcomings of the existing research,the direction of future research was finally determined.The current work offers a clear understanding of the HDR of blade-like structures,which could improve the evaluation accuracy of flow-induced vibration in the design stage. 展开更多
关键词 Blade fatigue Hydrodynamic damping ratio Identification method Affecting factors Prediction formula
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A New Technique for Constructing Higher-order Iterative Methods to Solve Nonlinear Systems
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作者 XIAO Xiaoyong 《应用数学》 北大核心 2025年第3期762-774,共13页
In this paper,a new technique is introduced to construct higher-order iterative methods for solving nonlinear systems.The order of convergence of some iterative methods can be improved by three at the cost of introduc... In this paper,a new technique is introduced to construct higher-order iterative methods for solving nonlinear systems.The order of convergence of some iterative methods can be improved by three at the cost of introducing only one additional evaluation of the function in each step.Furthermore,some new efficient methods with a higher-order of convergence are obtained by using only a single matrix inversion in each iteration.Analyses of convergence properties and computational efficiency of these new methods are made and testified by several numerical problems.By comparison,the new schemes are more efficient than the corresponding existing ones,particularly for large problem sizes. 展开更多
关键词 Systems of nonlinear equation Order of convergence Higher-order method Extended Newton iteration Computational efficiency
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A comprehensive evaluation of RNA secondary structures prediction methods
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作者 Xinlong Chen En Lou +2 位作者 Zouchenyu Zhou Ya-Lan Tan Zhi-Jie Tan 《Chinese Physics B》 2025年第8期115-127,共13页
RNAs have important biological functions and the functions of RNAs are generally coupled to their structures, especiallytheir secondary structures. In this work, we have made a comprehensive evaluation of the performa... RNAs have important biological functions and the functions of RNAs are generally coupled to their structures, especiallytheir secondary structures. In this work, we have made a comprehensive evaluation of the performances of existingtop RNA secondary structure prediction methods, including five deep-learning (DL) based methods and five minimum freeenergy (MFE) based methods. First, we made a brief overview of these RNA secondary structure prediction methods.Afterwards, we built two rigorous test datasets consisting of RNAs with non-redundant sequences and comprehensivelyexamined the performances of the RNA secondary structure prediction methods through classifying the RNAs into differentlength ranges and different types. Our examination shows that the DL-based methods generally perform better thanthe MFE-based methods for RNAs with long lengths and complex structures, while the MFE-based methods can achievegood performance for small RNAs and some specialized MFE-based methods can achieve good prediction accuracy forpseudoknots. Finally, we provided some insights and perspectives in modeling RNA secondary structures. 展开更多
关键词 RNA secondary structure prediction computational methods comprehensive evaluation traditional methods deep-learning-based methods
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Development prospects of residual stress detection methods
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作者 Xin LI Hanjun GAO Qiong WU 《Chinese Journal of Aeronautics》 2025年第7期601-603,共3页
In the aerospace field, residual stress directly affects the strength, fatigue life and dimensional stability of thin-walled structural components, and is a key factor to ensure flight safety and reliability. At prese... In the aerospace field, residual stress directly affects the strength, fatigue life and dimensional stability of thin-walled structural components, and is a key factor to ensure flight safety and reliability. At present, research on residual stress at home and abroad mainly focuses on the optimization of traditional detection technology, stress control of manufacturing process and service performance evaluation, among which research on residual stress detection methods mainly focuses on the improvement of the accuracy, sensitivity, reliability and other performance of existing detection methods, but it still faces many challenges such as extremely small detection range, low efficiency, large error and limited application range. 展开更多
关键词 residual stress flight safety reliability detection methods optimization traditional detection technology residual stress detection methods service performance evaluation IMPROVEMENT stress control
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Novel adaptive IMEX two-step Runge-Kutta temporal discretization methods for unsteady flows
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作者 Xueyu QIN Jian YU +2 位作者 Xin ZHANG Zhenhua JIANG Chao YAN 《Chinese Journal of Aeronautics》 2025年第8期142-153,共12页
Efficient and accurate simulation of unsteady flow presents a significant challenge that needs to be overcome in computational fluid dynamics.Temporal discretization method plays a crucial role in the simulation of un... Efficient and accurate simulation of unsteady flow presents a significant challenge that needs to be overcome in computational fluid dynamics.Temporal discretization method plays a crucial role in the simulation of unsteady flows.To enhance computational efficiency,we propose the Implicit-Explicit Two-Step Runge-Kutta(IMEX-TSRK)time-stepping discretization methods for unsteady flows,and develop a novel adaptive algorithm that correctly partitions spatial regions to apply implicit or explicit methods.The novel adaptive IMEX-TSRK schemes effectively handle the numerical stiffness of the small grid size and improve computational efficiency.Compared to implicit and explicit Runge-Kutta(RK)schemes,the IMEX-TSRK methods achieve the same order of accuracy with fewer first derivative calculations.Numerical case tests demonstrate that the IMEX-TSRK methods maintain numerical stability while enhancing computational efficiency.Specifically,in high Reynolds number flows,the computational efficiency of the IMEX-TSRK methods surpasses that of explicit RK schemes by more than one order of magnitude,and that of implicit RK schemes several times over. 展开更多
关键词 Implicit-explicit temporal methods Two-step Runge-Kutta methods Adaptive algorithm Unsteady flows Navier-Stokes equations
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A Comprehensive Study on Application and Prospect of Hydrogel Detection Methods
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作者 Caixia Chen Pengyu Liu +3 位作者 Changhua Wang Yanyan Xie Wei Wang Xiaomin Kang 《Journal of Polymer Materials》 2025年第3期621-660,共40页
Due to their high water content,stimulus responsiveness,and biocompatibility,hydrogels,which are functional materials with a three-dimensional network structure,are widely applied in fields such as biomedicine,environ... Due to their high water content,stimulus responsiveness,and biocompatibility,hydrogels,which are functional materials with a three-dimensional network structure,are widely applied in fields such as biomedicine,environmental monitoring,and flexible electronics.This paper provides a systematic review of hydrogel charac-terization methods and their applications,focusing on primary evaluation techniques for physical properties(e.g.,mechanical strength,swelling behavior,and pore structure),chemical properties(e.g.,composition,crosslink density,and degradation behavior),biocompatibility,and functional properties(e.g.,drug release,environmental stimulus response,and conductivity).It analyzes the challenges currently faced by characterization methods,such as a lack of standardization,difficulties in dynamic monitoring,an insufficient micro-macro correlation,and poor adaptability to complex environments.It proposes solutions,such as a hierarchical standardization system,in situ imaging technology,cross-scale characterization,and biomimetic testing platforms.Looking ahead,hydrogel characterization techniques will evolve toward intelligent,real-time,multimodal coupling and standardized approaches.These techniques will provide superior technical support for precision medicine,environmental restoration,and flexible electronics.They will also offer systematic methodological guidance for the performance optimization and practical application of hydrogel materials. 展开更多
关键词 HYDROGEL characterization methods PROPERTIES STANDARDIZATION APPLICATION
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Research on the strength detection methods of railway tunnel linings
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作者 Weiyi Yang 《Railway Sciences》 2025年第5期638-646,共9页
Purpose–For the commonly used concrete mix for railway tunnel linings,concrete model specimens were made,and springback and core drilling tests were conducted at different ages.The springback strength was measured to... Purpose–For the commonly used concrete mix for railway tunnel linings,concrete model specimens were made,and springback and core drilling tests were conducted at different ages.The springback strength was measured to the compressive strength of the core sample with a diameter of 100mm and a height-to-diameter ratio of 1:1.By comparing the measured strength values,the relationship between the measured values under different strength measurement methods was analyzed.Design/methodology/approach–A comparative test of the core drilling method and the rebound method was conducted on the side walls of tunnel linings in some under-construction railways to study the feasibility of the rebound method in engineering quality supervision and inspection.Findings–Tests showed that the rebound strength was positively correlated with the core drill strength.The core drill test strength was significantly higher than the rebound test strength,and the strength still increased after 56 days of age.The rebound method is suitable for the general survey of concrete strength during the construction process and is not suitable for direct supervision and inspection.Originality/value–By studying the correlation of test strength of tunnel lining concrete using two methods,the differences in test results of different methods are proposed to provide a reference for the test and evaluation of tunnel lining strength in railway engineering. 展开更多
关键词 Tunnel lining CONCRETE STRENGTH Rebound method Core drilling method
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New interpretation methods for rockhead determination using passive seismic surface wave data:Insights from Singapore
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作者 Yu Zhang Jian Chu +1 位作者 Shifan Wu Kiefer Chiam 《Journal of Rock Mechanics and Geotechnical Engineering》 2025年第7期4008-4019,共12页
Accurate determination of rockhead is crucial for underground construction.Traditionally,borehole data are mainly used for this purpose.However,borehole drilling is costly,time-consuming,and sparsely distributed.Non-i... Accurate determination of rockhead is crucial for underground construction.Traditionally,borehole data are mainly used for this purpose.However,borehole drilling is costly,time-consuming,and sparsely distributed.Non-invasive geophysical methods,particularly those using passive seismic surface waves,have emerged as viable alternatives for geological profiling and rockhead detection.This study proposes three interpretation methods for rockhead determination using passive seismic surface wave data from Microtremor Array Measurement(MAM)and Horizontal-to-Vertical Spectral Ratio(HVSR)tests.These are:(1)the Wavelength-Normalized phase velocity(WN)method in which a nonlinear relationship between rockhead depth and wavelength is established;(2)the Statistically Determined-shear wave velocity(SD-V_(s))method in which the representative V_(s) value for rockhead is automatically determined using a statistical method;and(3)the empirical HVSR method in which the rockhead is determined by interpreting resonant frequencies using a reliably calibrated empirical equation.These methods were implemented to determine rockhead depths at 28 locations across two distinct geological formations in Singapore,and the results were evaluated using borehole data.The WN method can determine rockhead depths accurately and reliably with minimal absolute errors(average RMSE=3.11 m),demonstrating robust performance across both geological formations.Its advantage lies in interpreting dispersion curves alone,without the need for the inversion process.The SD-V_(s) method is practical in engineering practice owing to its simplicity.The empirical HVSR method reasonably determines rockhead depths with moderate accuracy,benefiting from a reliably calibrated empirical equation. 展开更多
关键词 Rockhead Microtremor array measurement Horizontal-to-vertical spectral ratio Site investigation GEOPHYSICS Interpretation methods
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Review on internal flow mechanism and control methods of axial flow compressor at low Reynolds number
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作者 Xuyang REN Xingen LU +6 位作者 Mingyang WANG Ge HAN Chengwu YANG Xu DONG Lipan YAO Yanfeng ZHANG Shengfeng ZHAO 《Chinese Journal of Aeronautics》 2025年第5期7-27,共21页
With the continuous increase of aeroengine flight ceiling(>20 km),the thin atmosphere at high altitudes and the size effect all cause the compressor component inlet Reynolds number to decrease rapidly to a critical... With the continuous increase of aeroengine flight ceiling(>20 km),the thin atmosphere at high altitudes and the size effect all cause the compressor component inlet Reynolds number to decrease rapidly to a critical value(approximately 2.0×10^(5)),and the significant transition process on the blade/endwall surface leads to the sharp degradation of compressor performance,which seriously affects the engine fuel consumption and working stability at high altitudes.In this paper,the research progress on the internal flow mechanism and flow control methods of axial compressors at low Reynolds numbers is reviewed from the aspects of quantification and prediction of performance variation,flow loss mechanism related to separation and transition,efficient transition control and flow field organization.The development trend of the low-Reynolds-number effect of axial flow compressors is noted,and the difficulties and application prospects of aerodynamic design and efficient flow control methods for compressors under low Reynolds numbers at high altitudes are discussed. 展开更多
关键词 LowReynolds number Axial compressor Flow mechanism Flow control methods AEROENGINE
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Research on the Translation Methods for Reduplicatives in Xu Yuanchong’s English Translation of the Chu ci
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作者 YANGCHEN Mingwan TIAN Chuanmao 《译苑新谭》 2025年第1期1-19,共19页
This study examines the translation methods employed by Xu Yuanchong in his English translation of the Chu ci with a specific focus on the treatment of reduplicatives.Reduplicatives in the Chinese language,known for t... This study examines the translation methods employed by Xu Yuanchong in his English translation of the Chu ci with a specific focus on the treatment of reduplicatives.Reduplicatives in the Chinese language,known for their intricate nature of meaning and rhythmic qualities,pose a great challenge in translation due to the lack of equivalent structures in English.The paper investigates how Xu Yuanchong navigates these challenges by employing various strategies,including repetition,onomatopoeia,paraphrase,and literal translation without formal equivalence.Through an analysis of selected examples,the research highlights the difficulties of balancing Xu’s Three Beauties Principle,namely the beauty in sense,sound,and form in translating reduplicatives.The research findings are that,while Xu’s translations sometimes require compromises in sound and form,his nuanced approach ensures that the essence and emotional depth of the original text are effectively conveyed to target readers.This study may contribute to a deeper understanding of the complexities involved in translating classical Chinese poetry and offer insights into the interplay between linguistic and cultural elements in literary translation. 展开更多
关键词 Chu ci reduplicatives Xu Yuanchong Three Beauties Principle translation methods
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General Improvement of Image Interpolation-Based Data Hiding Methods Using Multiple-Based Number Conversion
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作者 Da-Chun Wu Bing-Han 《Computer Modeling in Engineering & Sciences》 2025年第7期535-580,共46页
Data hiding methods involve embedding secret messages into cover objects to enable covert communication in a way that is difficult to detect.In data hiding methods based on image interpolation,the image size is reduce... Data hiding methods involve embedding secret messages into cover objects to enable covert communication in a way that is difficult to detect.In data hiding methods based on image interpolation,the image size is reduced and then enlarged through interpolation,followed by the embedding of secret data into the newly generated pixels.A general improving approach for embedding secret messages is proposed.The approach may be regarded a general model for enhancing the data embedding capacity of various existing image interpolation-based data hiding methods.This enhancement is achieved by expanding the range of pixel values available for embedding secret messages,removing the limitations of many existing methods,where the range is restricted to powers of two to facilitate the direct embedding of bit-based messages.This improvement is accomplished through the application of multiple-based number conversion to the secret message data.The method converts the message bits into a multiple-based number and uses an algorithm to embed each digit of this number into an individual pixel,thereby enhancing the message embedding efficiency,as proved by a theorem derived in this study.The proposed improvement method has been tested through experiments on three well-known image interpolation-based data hiding methods.The results show that the proposed method can enhance the three data embedding rates by approximately 14%,13%,and 10%,respectively,create stego-images with good quality,and resist RS steganalysis attacks.These experimental results indicate that the use of the multiple-based number conversion technique to improve the three interpolation-based methods for embedding secret messages increases the number of message bits embedded in the images.For many image interpolation-based data hiding methods,which use power-of-two pixel-value ranges for message embedding,other than the three tested ones,the proposed improvement method is also expected to be effective for enhancing their data embedding capabilities. 展开更多
关键词 Data hiding image interpolation interpolation-based hiding methods steganography multiple-based number conversion
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Confidence Intervals for the Reliability of Dependent Systems:Integrating Frailty Models and Copula-Based Methods
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作者 Osnamir E.Bru-Cordero Cecilia Castro +1 位作者 Victor Leiva Mario C.Jaramillo-Elorza 《Computer Modeling in Engineering & Sciences》 2025年第5期1401-1431,共31页
Most reliability studies assume large samples or independence among components,but these assump-tions often fail in practice,leading to imprecise inference.We address this issue by constructing confidence intervals(CI... Most reliability studies assume large samples or independence among components,but these assump-tions often fail in practice,leading to imprecise inference.We address this issue by constructing confidence intervals(CIs)for the reliability of two-component systems with Weibull distributed failure times under a copula-frailty framework.Our construction integrates gamma-distributed frailties to capture unobserved heterogeneity and a copula-based dependence structure for correlated failures.The main contribution of this work is to derive adjusted CIs that explicitly incorporate the copula parameter in the variance-covariance matrix,achieving near-nominal coverage probabilities even in small samples or highly dependent settings.Through simulation studies,we show that,although traditional methods may suffice with moderate dependence and large samples,the proposed CIs offer notable benefits when dependence is strong or data are sparse.We further illustrate our construction with a synthetic example illustrating how penalized estimation can mitigate the issue of a degenerate Hessian matrix under high dependence and limited observations,so enabling uncertainty quantification despite deviations from nominal assumptions.Overall,our results fill a gap in reliability modeling for systems prone to correlated failures,and contribute to more robust inference in engineering,industrial,and biomedical applications. 展开更多
关键词 Censored data copula methods dependent failure times interval estimation Weibull distribution
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Retrospective comparative study of different surgical methods for gastric ulcer perforation:Efficacy and postoperative complications
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作者 Yu-Fan Pang Liang Shu Cheng-Wei Xia 《World Journal of Gastrointestinal Surgery》 2025年第2期154-160,共7页
BACKGROUND Gastric ulcer perforation is a critical condition that can lead to significant morbidity and mortality if not promptly addressed.It is often the result of chronic peptic ulcer disease,which is characterized... BACKGROUND Gastric ulcer perforation is a critical condition that can lead to significant morbidity and mortality if not promptly addressed.It is often the result of chronic peptic ulcer disease,which is characterized by a breach in the gastric wall due to ulceration.Surgical intervention is essential for managing this life-threatening complication.However,the optimal surgical technique remains debatable among clinicians.Various methods have been employed,including simple closure,omental patch repair,and partial gastrectomy,each with distinct advantages and disadvantages.Understanding the comparative efficacy and postoperative outcomes of these techniques is crucial for improving patient care and surgical decision-making.This study addresses the need for a comprehensive analysis in this area.AIM To compare the efficacy and postoperative complications of different surgical methods for the treatment of gastric ulcer perforation.METHODS A retrospective analysis was conducted on 120 patients who underwent surgery for gastric ulcer perforation between September 2020 and June 2023.The patients were divided into three groups based on the surgical method:Simple closure,omental patch repair,and partial gastrectomy.The primary outcomes were the operative success rate and incidence of postoperative complications.Secondary outcomes included the length of hospital stay,recovery time,and long-term quality of life.RESULTS The operative success rates for simple closure,omental patch repair,and partial gastrectomy were 92.5%,95%,and 97.5%,respectively.Postoperative complications occurred in 20%,15%,and 17.5%of patients in each group,respectively.The partial gastrectomy group showed a significantly longer operative time(P<0.001)but the lowest rate of ulcer recurrence(2.5%,P<0.05).The omental patch repair group demonstrated the shortest hospital stay(mean 7.2 days,P<0.05)and fastest recovery time.CONCLUSION While all three surgical methods showed high success rates,omental patch repair demonstrated the best overall outcomes,with a balance of high efficacy,low complication rates,and shorter recovery time.However,the choice of the surgical method should be tailored to individual patient factors and the surgeon’s expertise. 展开更多
关键词 Gastric ulcer perforation Surgical methods Simple closure Omental patch repair Partial gastrectomy Postoperative complications
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Advances in Research of Characteristics, Environmental Impact and Treatment Methods of Dairy Wastewater
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作者 Jiping XIE Ming QIAO +1 位作者 Ying BAI Li SONG 《Asian Agricultural Research》 2025年第3期18-21,39,共5页
Dairy wastewater,a kind of high concentration organic wastewater,is produced in large quantities and difficult to treat,and has a negative impact on the ecological environment.In this study,the source,composition,wate... Dairy wastewater,a kind of high concentration organic wastewater,is produced in large quantities and difficult to treat,and has a negative impact on the ecological environment.In this study,the source,composition,water quality characteristics of dairy wastewater and its impact on the ecological environment were analyzed,and the treatment methods of dairy wastewater at home and abroad in recent years were summarized,in order to provide a reference for the treatment of dairy wastewater. 展开更多
关键词 Dairy products WASTEWATER Treatment methods Advances in research
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A review of research methods for elucidating the microstructure of pharmaceutical preparations
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作者 Peng Yan Zhiyuan Hou Jinsong Ding 《Journal of Pharmaceutical Analysis》 2025年第5期901-915,共15页
The microstructures of pharmaceutical preparations play a pivotal role in determining their critical quality attributes(CQAs),such as drug release,content uniformity,and stability,which greatly impact the safety and e... The microstructures of pharmaceutical preparations play a pivotal role in determining their critical quality attributes(CQAs),such as drug release,content uniformity,and stability,which greatly impact the safety and efficacy of drugs.Unlike the inherent molecular structures of active pharmaceutical ingredients(APIs)and excipients,the microstructures of pharmaceutical preparations are developed during the formulation process,presenting unique analytical challenges.In this review,we primarily focus on presenting the research methods used to elucidate the microstructures of pharmaceutical preparations,including X-ray imaging(XRI),scanning electron microscopy(SEM),atomic force microscopy(AFM),Raman spectroscopy,infrared(IR)spectroscopy,and rheometer technology.Subsequently,we highlight the applications,advantages,and limitations of these methods.Finally,we discuss the current challenges and future perspectives in this field.This review aims to provide a comprehensive reference for understanding the microstructures of pharmaceutical preparations,offering new insights and potential advancements in their development. 展开更多
关键词 MICROSTRUCTURE Pharmaceutical preparation Critical quality attributes Research methods
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The Acoustic Attenuation Prediction for Seafloor Sediment Based on in-situ Data and Machine Learning Methods
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作者 WANG Jingqiang HOU Zhengyu +6 位作者 CHEN Yinglin LI Guanbao KAN Guangming XIAO Peng LI Zhenglin MO Dinghao HUANG Jingyi 《Journal of Ocean University of China》 2025年第1期95-102,共8页
Accurate acquisition and prediction of acoustic parameters of seabed sediments are crucial in marine sound propagation research.While the relationship between sound velocity and physical properties of sediment has bee... Accurate acquisition and prediction of acoustic parameters of seabed sediments are crucial in marine sound propagation research.While the relationship between sound velocity and physical properties of sediment has been extensively studied,there is still no consensus on the correlation between acoustic attenuation coefficient and sediment physical properties.Predicting the acoustic attenuation coefficient remains a challenging issue in sedimentary acoustic research.In this study,we propose a prediction method for the acoustic attenuation coefficient using machine learning algorithms,specifically the random forest(RF),support vector machine(SVR),and convolutional neural network(CNN)algorithms.We utilized the acoustic attenuation coefficient and sediment particle size data from 52 stations as training parameters,with the particle size parameters as the input feature matrix,and measured acoustic attenuation as the training label to validate the attenuation prediction model.Our results indicate that the error of the attenuation prediction model is small.Among the three models,the RF model exhibited the lowest prediction error,with a mean squared error of 0.8232,mean absolute error of 0.6613,and root mean squared error of 0.9073.Additionally,when we applied the models to predict the data collected at different times in the same region,we found that the models developed in this study also demonstrated a certain level of reliability in real prediction scenarios.Our approach demonstrates that constructing a sediment acoustic characteristics model based on machine learning is feasible to a certain extent and offers a novel perspective for studying sediment acoustic properties. 展开更多
关键词 in-situ measurement ATTENUATION seafloor sediment machine learning methods
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A Study on the Investigation Methods of Jesuit Father d'Entrecolles Regarding Jingdezhen Porcelain Production Techniques
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作者 YANG Min LI Xue +1 位作者 MIAO Lifeng ZHENG Naizhang 《Cultural and Religious Studies》 2025年第9期518-525,共8页
In the early 18th century,to meet Europe's urgent demand for Jingdezhen's ceramic production techniques,French Jesuit missionary François Xavier d'Entrecolles traveled to Jingdezhen,Jiangxi.While cond... In the early 18th century,to meet Europe's urgent demand for Jingdezhen's ceramic production techniques,French Jesuit missionary François Xavier d'Entrecolles traveled to Jingdezhen,Jiangxi.While conducting missionary work,he thoroughly investigated local porcelain-making techniques.He compiled his findings into two lengthy letters and sent samples of porcelain raw materials to Europe,successfully disseminating Jingdezhen's ceramic artistry to the continent.D'Entrecolles skillfully integrated the protective function of his religious identity,the resource coordination capabilities of political networks,the documentation methods of empirical science,and a localized infiltration strategy,constructing a four-dimensional investigative framework of"missionary integration-observation and interviews-literature review-experimental verification"through Broussonetia papyrifera.These systematic research methods enabled him to comprehensively master Jingdezhen's porcelain technology at the time,establishing him as the pioneer of Western systematic studies on Chinese ceramics and creating a new paradigm of"field research+scientific empiricism"in early cross-cultural technological transmission. 展开更多
关键词 the society of Jesus Father d'Entrecolles Jingdezhen porcelain manufacturing techniques investigation methods
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