The growing interest in Honeypots has resulted in increased research, and consequently, a large number of research surveys and/or reviews. Most Honeypot surveys and/or reviews focus on specific and narrow Honeypot res...The growing interest in Honeypots has resulted in increased research, and consequently, a large number of research surveys and/or reviews. Most Honeypot surveys and/or reviews focus on specific and narrow Honeypot research areas. This study aims at exploring and presenting advances and trends in Honeypot’s research and development areas. To this end, a systematic methodology and meta-review analysis were applied to the selection, evaluation, and qualitative examination of the most influential Honeypot surveys and/or reviews available in scientific bibliographic databases. A total of 188 papers have been evaluated and 22 research papers are found by this study to have a higher impact. The findings of the study suggest that the Honeypot survey and/or review papers of considerable relevance to the research community were mostly published in 2018, by IEEE, in conferences organized in India, and included in the IEEE Xplore database. Also, there have been few qualities Honeypot surveys and/or reviews published after 2018. Furthermore, the study identified 10 classes of vital and emerging themes and/or key topics in Honeypot research. This work contributes to research efforts employing established systematic review and reporting methods in Honeypot research. We have included our meta-review methodology, in order to allow further work in this area aiming at a better understanding of the progression of Honeypot research and advances.展开更多
Sustainable aviation fuel(SAF)offers various pathways to mitigate the aviation industry’s significant carbon footprint.Over the past years,the SAF research landscape has seen a proliferation of overview/survey papers...Sustainable aviation fuel(SAF)offers various pathways to mitigate the aviation industry’s significant carbon footprint.Over the past years,the SAF research landscape has seen a proliferation of overview/survey papers across diverse domains,driven by an increasing number of primary studies.The fragmentation of these papers across disciplinary boundaries,however,has a strong potential to prevent a comprehensive understanding of SAF state of the art and advancements.In this meta-review,we synthesize insights from the extant SAF survey literature.By systematically analyzing over 60 survey/overview papers on feedstock production,fuel synthesis technologies,lifecycle assessments,policy frameworks,economic viability,and intersections thereof,our review identifies recurring themes and emerging technologies regarding SAF research.Our meta-review also underscores the need of orchestrated future research efforts,by consolidating the top-10 fragmented SAF challenges across all surveys.We highlight feedstock availability problems,opportunities for scaling up production while maintaining sustainability criteria,fostering cooperation,and harmonizing SAF certification standards,among others.Our meta-review seeks to serve as a navigational tool for researchers,policymakers,and industry stakeholders alike,laying the foundation for a more effective and impactful orchestration of future work towards decarbonizing global aviation.展开更多
本文旨在系统评价极低热量生酮饮食(VLCKD)、地中海饮食(MD)与间歇性禁食(IF)对肥胖人群肠道菌群的影响。截至2025年9月,检索PubMed、EBSCOhost、Cochrane和Web of Science四个电子数据库。采用R软件进行荟萃(meta)分析,评估肠道菌群多...本文旨在系统评价极低热量生酮饮食(VLCKD)、地中海饮食(MD)与间歇性禁食(IF)对肥胖人群肠道菌群的影响。截至2025年9月,检索PubMed、EBSCOhost、Cochrane和Web of Science四个电子数据库。采用R软件进行荟萃(meta)分析,评估肠道菌群多样性和特征菌群丰度变化。依据身体质量指数(BMI)、年龄和干预周期等变量开展亚组分析。共纳入42项研究。通过随机效应荟萃分析,结果显示,VLCKD显著提升Shannon指数、观测到的操作分类单元(Observed OTU)和系统发育多样性(phylogenetic diversity,PD)指数,并增加阿克曼菌属丰度与厚壁菌门/拟杆菌门比值(F/B比值),但伴随双歧杆菌属丰度的显著下降,提示其双向调节效应。MD干预显著增加Shannon指数、阿克曼菌属和双歧杆菌属丰度,同时降低厚壁菌门和F/B比值,整体呈现稳定、持续的正向作用。IF干预会导致PD指数和厚壁菌门下降、阿克曼菌属上升,但长期干预时Shannon指数出现回落,显示其稳定性有限。亚组分析提示,年龄与BMI是影响菌群多样性和特征菌群变化的重要调节因素。VLCKD、MD与IF均可在肥胖人群中改善肠道菌群结构,但效应特征存在显著差异。VLCKD调节效应强烈但伴随潜在风险,MD稳定性与安全性较高,而IF效果更具选择性且容易导致肥胖人群暴饮暴食,故需要进一步研究其长期可行性和安全性。未来研究应聚焦于膳食模式的最优周期与联合应用,并结合人群特异的饮食习惯和菌群特征,发展个体化的微生态干预策略。展开更多
目的:系统评价头针治疗孤独症谱系障碍(ASD)的有效性与安全性。方法:计算机检索PubMed、EMbase、The Cochrane Library、Web of Science、中国生物医学文献数据库、中国知网、维普、万方数据库,搜集有关头针治疗ASD的随机对照试验。采用...目的:系统评价头针治疗孤独症谱系障碍(ASD)的有效性与安全性。方法:计算机检索PubMed、EMbase、The Cochrane Library、Web of Science、中国生物医学文献数据库、中国知网、维普、万方数据库,搜集有关头针治疗ASD的随机对照试验。采用RevMan 5.4.1软件进行Meta分析。结果:共纳入33个随机对照试验,包括2701例患者。Meta分析结果显示:较康复训练组,头针结合康复训练能够显著降低孤独症行为评定量表评分[MD=-5.70,95%CI(-6.51,-4.89),P<0.01]、儿童孤独症评定量表评分[MD=-4.02,95%CI(-4.38,-3.66),P<0.01],提高盖塞尔发展诊断量表(Gesell)-社会适应发育商[MD=5.90,95%CI(4.29,7.51),P<0.01]、Gesell-语言发育商[MD=4.39,95%CI(3.03,5.75),P<0.01]、Gesell-个人社交[MD=4.32,95%CI(2.48,6.15),P<0.01]、儿童心理教育评估第3版(PEP-3)-沟通评分[MD=3.76,95%CI(3.25,4.27),P<0.01]、PEP-3-体能评分[MD=1.99,95%CI(1.40,2.59),P<0.01]、PEP-3-行为评分[MD=2.18,95%CI(1.77,2.59),P<0.01]。结论:头针治疗能够有效改善孤独症患儿语言、行为、社交适应等方面症状,且安全性较高。受限于纳入文献的研究方法质量不高、融合了不同严重程度与年龄的受试者等原因,本研究结论尚需要更多高质量、长期随访的研究来验证。展开更多
目的系统评价我国脑卒中的发病率、死亡率和疾病负担。方法计算机检索CNKI、WanFang Data、VIP、CBM、PubMed、Embase、Web of Science和Cochrane Library数据库,搜集关于中国脑卒中流行病学和疾病负担的队列研究,检索时限均从建库至202...目的系统评价我国脑卒中的发病率、死亡率和疾病负担。方法计算机检索CNKI、WanFang Data、VIP、CBM、PubMed、Embase、Web of Science和Cochrane Library数据库,搜集关于中国脑卒中流行病学和疾病负担的队列研究,检索时限均从建库至2024年6月30日。由2位研究者独立筛选文献、提取资料并评价纳入研究的偏倚风险后,采用Stata 18.0软件进行Meta分析。结果共纳入49项研究,结果显示:我国脑卒中总体发病率为430/10万[95%CI(370/10万,490/10万)];男性脑卒中发病率为510/10万[95%CI(450/10万,580/10万)];女性脑卒中发病率为370/10万[95%CI(320/10万,410/10万)]。我国脑卒中总体死亡率为220/10万[95%CI(160/10万,280/10万)];男性脑卒中死亡率为160/10万[95%CI(120/10万,190/10万)];女性脑卒中死亡率为130/10万[95%CI(100/10万,160/10万)]。我国脑卒中平均标化DALY率为2238.09/10万,男性(3510.53/10万)高于女性(2083.39/10万)。结论我国男性脑卒中风险显著高于女性,主要归因于男性较高的吸烟饮酒率、不良饮食习惯以及对健康管理的忽视。此外,不同区域间的老龄化程度差异,尤其是东部和北部地区较高的老龄化水平,也对这些地区的脑卒中发病率产生了显著影响。展开更多
目的系统评价食管癌患者术后吻合口瘘(anastomotic leakage,AL)风险预测模型,为建立和改进模型提供指导。方法计算机检索PubMed、Cochrane Library、EMbase、Web of Science、中华医学期刊全文数据库、维普网、万方、中国生物医学文献...目的系统评价食管癌患者术后吻合口瘘(anastomotic leakage,AL)风险预测模型,为建立和改进模型提供指导。方法计算机检索PubMed、Cochrane Library、EMbase、Web of Science、中华医学期刊全文数据库、维普网、万方、中国生物医学文献数据库以及中国知网发表的关于食管癌术后AL风险预测模型的研究,检索时间为建库至2023年10月1日。采用PROBAST工具评估预测模型研究的质量,采用Stata 15软件对建立模型的预测变量进行Meta分析。结果纳入19篇文献,共构建25个食管癌患者术后AL风险预测模型,7373例患者,受试者工作特征曲线下面积(area under the curve,AUC)为0.670~0.960,其中23个预测模型的预测性能较好(AUC>0.7)。13篇文献进行了模型校准,10篇文献进行内部验证,1篇文献进行外部验证。PROBAST评价结果表明19篇文献均为高偏倚风险。最常见的预测因子包括:低蛋白血症(OR=9.362)、术后呼吸系统并发症(OR=7.427)、切口愈合不良(OR=5.330)、吻合方法(OR=2.965)、术前胸腹部手术史(OR=3.181)、术前合并糖尿病(OR=2.445)、术前合并心血管系统疾病(OR=3.260)、术前新辅助治疗(OR=2.977)、术前呼吸系统疾病(OR=4.744)、手术方式(OR=4.312)、美国麻醉医师协会评分(OR=2.424)等。结论目前食管癌术后AL风险预测模型仍处于研发阶段,总体研究质量有待进一步提升。展开更多
目的系统评价肺段切除术与肺叶切除术治疗T1c期非小细胞肺癌(non-small cell lung cancer,NSCLC)的疗效及安全性。方法系统检索PubMed、EMbase、Cochrane Central Register of Controlled Trials(CENTRAL)、中国知网、万方数据库,检索...目的系统评价肺段切除术与肺叶切除术治疗T1c期非小细胞肺癌(non-small cell lung cancer,NSCLC)的疗效及安全性。方法系统检索PubMed、EMbase、Cochrane Central Register of Controlled Trials(CENTRAL)、中国知网、万方数据库,检索时限为建库至2024年2月。由3名研究人员独立筛选文献,提取相关资料并对纳入的文献依据纽卡斯尔-渥太华量表(Newcastle-Ottawa Scale,NOS)进行偏倚风险评价。采用STATA 15.1进行Meta分析。结果共纳入8个回顾性队列研究,发表于2004—2022年,共7433例患者。纳入研究NOS评分均≥7分。Meta分析结果显示,接受肺叶切除比接受肺段切除术患者的5年总生存率更高[校正HR=1.11,95%CI(0.99,1.24),P=0.042];两者3年总生存率[校正HR=0.88,95%CI(0.62,1.24)]、5年肺癌特异性生存率[校正HR=1.10,95%CI(0.80,1.51)]和5年无复发生存率[校正HR=1.23,95%CI(0.82,1.85)]差异均无统计学意义;接受肺段切除术患者不良事件发生风险低于肺叶切除术患者[OR=0.57,95%CI(0.37,0.90)]。亚组分析结果显示,在未纳入接受新辅助治疗患者的研究中,接受肺段切除术患者与接受肺叶切除患者5年总生存率差异无统计学意义[校正HR=1.02,95%CI(0.81,1.28)]。结论对于T1c期NSCLC患者,肺段切除术与肺叶切除术在长期生存方面差异无统计学意义,但接受肺段切除术的患者术后并发症发生率较低。未来还需要更多高质量的临床试验评估肺叶切除术与肺段切除术治疗T1c期NSCLC患者的有效性及安全性。展开更多
文摘The growing interest in Honeypots has resulted in increased research, and consequently, a large number of research surveys and/or reviews. Most Honeypot surveys and/or reviews focus on specific and narrow Honeypot research areas. This study aims at exploring and presenting advances and trends in Honeypot’s research and development areas. To this end, a systematic methodology and meta-review analysis were applied to the selection, evaluation, and qualitative examination of the most influential Honeypot surveys and/or reviews available in scientific bibliographic databases. A total of 188 papers have been evaluated and 22 research papers are found by this study to have a higher impact. The findings of the study suggest that the Honeypot survey and/or review papers of considerable relevance to the research community were mostly published in 2018, by IEEE, in conferences organized in India, and included in the IEEE Xplore database. Also, there have been few qualities Honeypot surveys and/or reviews published after 2018. Furthermore, the study identified 10 classes of vital and emerging themes and/or key topics in Honeypot research. This work contributes to research efforts employing established systematic review and reporting methods in Honeypot research. We have included our meta-review methodology, in order to allow further work in this area aiming at a better understanding of the progression of Honeypot research and advances.
基金supported by the National Natural Science Foundation of China(Grant No.U2233214,No.62250710166)the Beijing Science Foundation(IS24035).
文摘Sustainable aviation fuel(SAF)offers various pathways to mitigate the aviation industry’s significant carbon footprint.Over the past years,the SAF research landscape has seen a proliferation of overview/survey papers across diverse domains,driven by an increasing number of primary studies.The fragmentation of these papers across disciplinary boundaries,however,has a strong potential to prevent a comprehensive understanding of SAF state of the art and advancements.In this meta-review,we synthesize insights from the extant SAF survey literature.By systematically analyzing over 60 survey/overview papers on feedstock production,fuel synthesis technologies,lifecycle assessments,policy frameworks,economic viability,and intersections thereof,our review identifies recurring themes and emerging technologies regarding SAF research.Our meta-review also underscores the need of orchestrated future research efforts,by consolidating the top-10 fragmented SAF challenges across all surveys.We highlight feedstock availability problems,opportunities for scaling up production while maintaining sustainability criteria,fostering cooperation,and harmonizing SAF certification standards,among others.Our meta-review seeks to serve as a navigational tool for researchers,policymakers,and industry stakeholders alike,laying the foundation for a more effective and impactful orchestration of future work towards decarbonizing global aviation.
文摘本文旨在系统评价极低热量生酮饮食(VLCKD)、地中海饮食(MD)与间歇性禁食(IF)对肥胖人群肠道菌群的影响。截至2025年9月,检索PubMed、EBSCOhost、Cochrane和Web of Science四个电子数据库。采用R软件进行荟萃(meta)分析,评估肠道菌群多样性和特征菌群丰度变化。依据身体质量指数(BMI)、年龄和干预周期等变量开展亚组分析。共纳入42项研究。通过随机效应荟萃分析,结果显示,VLCKD显著提升Shannon指数、观测到的操作分类单元(Observed OTU)和系统发育多样性(phylogenetic diversity,PD)指数,并增加阿克曼菌属丰度与厚壁菌门/拟杆菌门比值(F/B比值),但伴随双歧杆菌属丰度的显著下降,提示其双向调节效应。MD干预显著增加Shannon指数、阿克曼菌属和双歧杆菌属丰度,同时降低厚壁菌门和F/B比值,整体呈现稳定、持续的正向作用。IF干预会导致PD指数和厚壁菌门下降、阿克曼菌属上升,但长期干预时Shannon指数出现回落,显示其稳定性有限。亚组分析提示,年龄与BMI是影响菌群多样性和特征菌群变化的重要调节因素。VLCKD、MD与IF均可在肥胖人群中改善肠道菌群结构,但效应特征存在显著差异。VLCKD调节效应强烈但伴随潜在风险,MD稳定性与安全性较高,而IF效果更具选择性且容易导致肥胖人群暴饮暴食,故需要进一步研究其长期可行性和安全性。未来研究应聚焦于膳食模式的最优周期与联合应用,并结合人群特异的饮食习惯和菌群特征,发展个体化的微生态干预策略。
文摘目的系统评价食管癌患者术后吻合口瘘(anastomotic leakage,AL)风险预测模型,为建立和改进模型提供指导。方法计算机检索PubMed、Cochrane Library、EMbase、Web of Science、中华医学期刊全文数据库、维普网、万方、中国生物医学文献数据库以及中国知网发表的关于食管癌术后AL风险预测模型的研究,检索时间为建库至2023年10月1日。采用PROBAST工具评估预测模型研究的质量,采用Stata 15软件对建立模型的预测变量进行Meta分析。结果纳入19篇文献,共构建25个食管癌患者术后AL风险预测模型,7373例患者,受试者工作特征曲线下面积(area under the curve,AUC)为0.670~0.960,其中23个预测模型的预测性能较好(AUC>0.7)。13篇文献进行了模型校准,10篇文献进行内部验证,1篇文献进行外部验证。PROBAST评价结果表明19篇文献均为高偏倚风险。最常见的预测因子包括:低蛋白血症(OR=9.362)、术后呼吸系统并发症(OR=7.427)、切口愈合不良(OR=5.330)、吻合方法(OR=2.965)、术前胸腹部手术史(OR=3.181)、术前合并糖尿病(OR=2.445)、术前合并心血管系统疾病(OR=3.260)、术前新辅助治疗(OR=2.977)、术前呼吸系统疾病(OR=4.744)、手术方式(OR=4.312)、美国麻醉医师协会评分(OR=2.424)等。结论目前食管癌术后AL风险预测模型仍处于研发阶段,总体研究质量有待进一步提升。
