BACKGROUND Although gastroscopy is a commonly used diagnostic and therapeutic technique,postoperative gastrointestinal dysfunction is prone to occur.Traditional Chinese medicine theory suggests that postoperative gast...BACKGROUND Although gastroscopy is a commonly used diagnostic and therapeutic technique,postoperative gastrointestinal dysfunction is prone to occur.Traditional Chinese medicine theory suggests that postoperative gastrointestinal disorders are related to spleen and stomach weakness.This study hypothesizes that the combination of acupoint application at the Ziwu Liuzhu acupoint and percutaneous acupoint electrical stimulation can promote postoperative gastrointestinal function recovery and alleviate stress reactions.AIM To investigate the effects of acupoint application of Ziwu Liuzhu combined with percutaneous acupoint electrical stimulation on postoperative gastrointestinal function recovery and stress response in patients undergoing gastrointestinal endoscopy surgery.METHODS A total of 120 patients who underwent gastroscopy surgery were selected and treated between October 2024 and January 2025.This study used a stratified block randomization method,and then allocated groups using computer-generated random number sequences(SAS 9.4 software).The groups were divided into two groups:A control group of 60 patients who received routine postoperative intervention measures,and an observation group of 60 patients who received acupuncture point application combined with transcutaneous acupoint electrical CONCLUSION The combination of percutaneous acupoint electrical stimulation in gastroscopy patients has been demonstrated to be both highly safe and effective.The benefits of this approach include the promotion of postoperative gastrointestinal function,the reduction of stress response,the attainment of optimal results,and the enhancement of patient satisfaction.展开更多
OBJECTIVE:To evaluate the effects of external application of warm meridian medicated wine and polarized light therapy combined with acupuncture on pain management following vertebroplasty. METHODS:A total of 120 patie...OBJECTIVE:To evaluate the effects of external application of warm meridian medicated wine and polarized light therapy combined with acupuncture on pain management following vertebroplasty. METHODS:A total of 120 patients with osteoporotic vertebral compression fractures treated by vertebroplasty at our hospital were divided into four groups. The control group received non-steroidal anti-inflammatory drugs, the Treatment Group Ⅰ received acupuncture alone, Treatment Group Ⅱ was treated with medicated wine for warming meridians alongside polarized light physiotherapy, and Treatment Group Ⅲ received a combination of medicated wine for warming meridians, polarized light therapy, and acupuncture. The clinical efficacy, pain thresholds at various time points, temperature pain threshold, electric pain threshold, quality of life, sleep quality index, lumbar dysfunction index, visual analog scale(VAS) scores, and incidence of adverse reactions were compared and analyzed across the four groups. RESULTS:The total clinical effective rate in Treatment Group Ⅲ was significantly higher than that in the control group, Treatment Group Ⅰ, and Treatment Group Ⅱ(P < 0.05). At 24 and 72 h post-treatment, the VAS scores, temperature pain thresholds, and electric pain thresholds in Treatment Group Ⅲ were significantly lower than those in the control group, Treatment Group Ⅰ, and Treatment Group Ⅱ(P < 0.05). Additionally, quality-of-life scores in Treatment Group Ⅲ were markedly higher compared to the control group, Treatment Group Ⅰ, and Treatment Group Ⅱ, while the Pittsburgh Sleep Quality Index scores, Oswestry Disability Index scores, and incidence of adverse reactions in Treatment Group Ⅲ were significantly lower than in the other groups(P < 0.05). CONCLUSION:The external application of warm meridian medicated wine and polarized light therapy combined with acupuncture significantly reduces postoperative pain following vertebroplasty, enhances lumbar function, and improves both sleep quality and overall quality of life for patients. This approach is recommended for clinical application.展开更多
Objective:To study the clinical efficacy of applying the Meridian Flow Low-Frequency Therapy Device combined with Chinese herbal enema for patients with acute and chronic pelvic inflammatory disease(PID).Methods:Sixty...Objective:To study the clinical efficacy of applying the Meridian Flow Low-Frequency Therapy Device combined with Chinese herbal enema for patients with acute and chronic pelvic inflammatory disease(PID).Methods:Sixty-two patients with acute and chronic PID admitted from January 2024 to October 2025 were selected and randomly divided into a standard group(n=31)and an experimental group(n=31).The standard group received conventional medication+Chinese herbal enema treatment.The experimental group received the Meridian Flow Low-Frequency Therapy Device in addition to the standard group’s treatment.The clinical efficacy,changes in inflammatory markers,and pelvic improvement were compared between the two groups.Results:The excellent-good rate of treatment in the experimental group was higher than that in the standard group(p<0.05).The levels of various inflammatory factors in the experimental group were lower than those in the standard group(all p<0.05).The improvement in pelvic mass diameter and pelvic effusion depth in the experimental group was superior to that in the standard group(both p<0.05).Conclusion:The Meridian Flow Low-Frequency Therapy Device combined with Chinese herbal enema has a definite curative effect in treating pelvic inflammatory disease.It can effectively alleviate clinical symptoms,reduce inflammatory response,and promote the improvement of the pelvic environment.展开更多
Objective To study the effect of the serum derived from the rats treated with electroacupunctre at Stomach Meridian acupoints on the EGFR signal transduction pathway in gastric mucosal cells. Methods Sixty rats were r...Objective To study the effect of the serum derived from the rats treated with electroacupunctre at Stomach Meridian acupoints on the EGFR signal transduction pathway in gastric mucosal cells. Methods Sixty rats were randomly divided into 5 groups： model group, Stomach （ST） Meridian group, Gallbladder （GB） Meridian group, ST＋ PD153035 group and GB＋ PD153035 group. Water-immersion and restrained stress method was adopted for preparation of the stress-induced gastric ulcer rat model, and the gastric mucosa cells were separated by using pronase digestion method. Gastric mucosa cells were incubated respectively with PD153035, EGFR inhibitor and the serum; PLCγ-1＇s expression level in gastric mucosa cells was tested by enzyme-linked immunosorbant assay （ELISA）, and PKC activity by isotope mingling method; and reverse transcription polymerase chain reaction assay （RT-PCR） was used for testing expression level of c-myc gene. Results The expression levels of PLCγ-1 ,PKC and c- myc gene were lower in gastric mucosa cells in the model group; there were relatively high expression levels of PLCγ-1 ,PKC and c-myc gene in the ST Meridian group and the GB Meridian group, with the highest expression levels of PLCγ-1 ,PKC and c-myc gene in the ST Meridian, and with a significant difference between the ST Meridian group and the GB Meridian group （P〈0.01 ） ; and relative lower expression levels of PLCγ-1, PKC and c-myc gene were seen in the ST ＋ PD153035 group and the GB ＋ PD153035 group; and there was a significant difference between the ST Meridian group and the ST ＋ PD153035 group （P〈0.01）. Conclusion There was a close correlation between the healing effect of electroacupuncture and activation of the EGFR signal transduction pathway in the impaired gastric mucosa cells, which was also one proof for the TCM theory： ＂There is relative specificity between the meridians and viscera＂.展开更多
Objective To compare the clinical therapeutic effects on scapulohumeral periarthritis between kinetic acupuncture on the distal points of the affected meridians and shoulder three-needle therapy.Methods Fifty cases of...Objective To compare the clinical therapeutic effects on scapulohumeral periarthritis between kinetic acupuncture on the distal points of the affected meridians and shoulder three-needle therapy.Methods Fifty cases of scapulohumeral periarthritis were randomly divided into an observation group and a control group,25 cases for each.The cases in observation group were treated with kinetic acupuncture on the distal points of the affected meridians.For example,the case of Hand-Taiyin type was treated with Yújì （鱼际 LU 10） and the case of Hand-Yangming type was treated with Hégǔ （合谷 LI 4）,etc.The cases in control group were treated with shoulder three-needle therapy,in which,Jiānqián （肩前 Extral）,Jiānyú （肩髃 LI 15） and Jiānliáo （肩髎 TE 14） were selected;7 days of treatment made one session,totally 2 sessions were required.Results In observation group,the curative rate based on ROM of shoulder joint was 72.0% （18/25）,which was superior to that of 40.0% （10/25） in control group （P0.05）.After treatment,the improvements of McGill SF-MPQ score,VAS and PPI in observation group were all superior to those in control group （all P0.05）.Conclusion The kinetic acupuncture on the distal points of the affected meridians is advantageous at analgesia and motor improvements of shoulder joint in treatment of scapulohumeral periarthritis as compared with shoulder three-needle therapy.展开更多
The peripheral driver stimulating theory states that as a driver passes along a certain meridian during acupuncture; the driver provokes nerve sense devices along the meridian, resulting in the nerve impulse entering ...The peripheral driver stimulating theory states that as a driver passes along a certain meridian during acupuncture; the driver provokes nerve sense devices along the meridian, resulting in the nerve impulse entering the central nervous system. Accordingly, volunteers have reported propagated sensations along the meridians （PSM）. The present study was designed to utilize a cortical somatosensory-evoked potential （CSEP） topographic map for determining whether stimulation expansion occurs in somatosensory area I when sensation was provoked in individuals with obvious PSM. The sensation was blocked by mechanical compression, and the sensation was imitated in individuals without PSM. Results revealed a red, high-potential signal in the representative area of the lower limbs in individuals with obvious PSM symptoms when the Gall Bladder Meridian （GBM） sensation passed to the head and face. This representative area was near the middle line of the CSEP topographic map, and a red, high-potential signal, which jumps over the representative area of the upper limbs, also appeared in the representative face area, which was at the external region of the CSEP topographic map. However, in individuals exhibiting no PSM, only a red high-potential signal appeared in the representative lower limb area. When Hegu （LI 4） was stimulated in individuals without PSM, an obvious evoked response appeared only in the representative upper limb area. However, when Hegu was stimulated in individuals exhibiting PSM, the response area was larger in the representative upper limb area and extended to the representative face area. When Guangrning （GB 37） was stimulated in PSM individuals, the face representation response disappeared and was confined to a foot representation of the somatosensory area I when PSM was blocked by mechanical pressure. Results suggested that mechanical compression blocked PSM, and corresponding changes were exhibited in the CSEP topographic map. These results provide compelling evidence for the hypothesis that peripheral driver stimulation is the key element in producing PSM.展开更多
Objective To explore the relationship between connexin 43 and acupoints and meridians. Methods we detected one major skin gap junction connexin （connexin43, Cx43） in meridians and acupoints, and studied the expressi...Objective To explore the relationship between connexin 43 and acupoints and meridians. Methods we detected one major skin gap junction connexin （connexin43, Cx43） in meridians and acupoints, and studied the expression of Cx43 in Zusanli （足三里 ST 36） acupoints compared with control non-acupoint regions in rats after acupuncture treatments. The expression of Cx43 was detected by using immunohisto- chemistry, immunoblotting, and RT-PCR for Cx43 protein and mRNA level. Results The results showed much more abundant Cx43 expression in some cells in the skin and subcutaneous tissue of rat at ST 36 acupoints and bladder and kidney meridians than that of in the controls. The mRNA and protein levels of Cx43 in acupoints were significantly higher than those of in the control points in non-acupuncture groups and even more so after acupuncture treatments. Conclusion Our research implied that connexins and gap junctions could have a close relationship to acupoints and meridians, and gap junctional intercellular communication might play an important role in the effect of acupuncture.展开更多
Objective To compare differences in therapeutic effects between acupuncture accelerating qi-flow along meridians （AQF） and conventional acupuncture （CA） in treating periarthritis of shoulder to find better acupunc...Objective To compare differences in therapeutic effects between acupuncture accelerating qi-flow along meridians （AQF） and conventional acupuncture （CA） in treating periarthritis of shoulder to find better acupuncture methods. Methods Sixty-four patients were randomly divided into two groups： group AQF, and group CA with 32 cases in each group. Jiānyú （肩髃 LI 15）, Jiānliáo （肩髎 TE 14）, Jiānzhēn （肩贞 SI 9）, Bìnào （臂臑 LI 14）, Qūchí （曲池 LI 11） and Wàiguān （外关 TE 5） on the affected side were used in both groups, and the two acupuncture methods were respectively used in the two groups for consecutive 2 courses. Pain and moving functions of shoulder and ability in daily life （ADL） were used as indices for evaluating therapeutic effects. Results The total effective rate was 96.9% （31/32） and 81.3% （26/32） in group AQF and group CA, respectively, showing superiority of AQF to CA （P〈0.05）. Scores reflecting pain and moving functions of shoulder and ADL were all improved after treatment in both groups （all P〈0.05）, and the improvement in group AQF was more obvious than those in group CA （all P〈0.05）. Conclusion In treating periarthritis of shoulder, the acupuncture accelerating qi-flow along meridians was better than conventional acupuncture in alleviating pain of the shoulder, improving its moving function and elevating abilities in daily life.展开更多
The Earth is buffered from the ferocious onslaught of the solar wind by a thin layer of matter known as the atmosphere and geospace.This layer absorbs energy from irradiance and outburst from the Sun,as well as from d...The Earth is buffered from the ferocious onslaught of the solar wind by a thin layer of matter known as the atmosphere and geospace.This layer absorbs energy from irradiance and outburst from the Sun,as well as from disasters,transient phenomena and anthropogenic emissions originated from Earth.Through complicated physics,the absorbed energy changes the atmospheric and geospace state and sometimes gets re-released to power extreme events such as space weather.Taking place globally,these complicated processes cannot be understood unless they are studied globally.The Chinese scientists have proposed the International Meridian Circle Program(IMCP)to meet this demand.By operating nearly 1000 instruments encompassing all latitudes along with the 120°E–60°W longitudes,IMCP aims,for the first time,to construct comprehensive 3D data representation of the atmosphere and geospace on a global scale and empower interdisciplinary research to tackle key questions related to Earth’s environment and climate change.展开更多
Through study on articles of fMRI and acupuncture-moxibustion of the recent 10 years, application of fMRI on specificity studies of meridians and acupoints such as comparison of single acupoint, point group, various m...Through study on articles of fMRI and acupuncture-moxibustion of the recent 10 years, application of fMRI on specificity studies of meridians and acupoints such as comparison of single acupoint, point group, various manipulations, essence of needling sensation and indications of acupuncture, etc. were summarized. And it is held that the future study should be focused on the entire meridian. The principle of the relationship among meridians, the centre nerve and Zang-fu organs should be explored as well at a new level so as to promote the further studies on essence of meridian.展开更多
The status quo of study on specificity of meridian acupoints is summarized in this article through retrieval of relative literatures published in the recent 10 years in databases such as CNKI and SCI. The result indic...The status quo of study on specificity of meridian acupoints is summarized in this article through retrieval of relative literatures published in the recent 10 years in databases such as CNKI and SCI. The result indicates that specificity, which is brought into play through the inner biological mechanism, can be found in meridian acupoint efficacy. However, problems still remain since studies at present are still not systematic, comprehensive and scientific. In the future, relative studies should be carried out on extensive diseases and disease models with modern scientific technologies and equipments, strict as well as scientific experimental designation and evaluation methods.展开更多
Background:Continuous and porous low hydraulic resistance channels(LHRCs)are important structures of meridians in traditional Chinese medicine(TCM).In this study,based on the previous research on LHRCs along meridian ...Background:Continuous and porous low hydraulic resistance channels(LHRCs)are important structures of meridians in traditional Chinese medicine(TCM).In this study,based on the previous research on LHRCs along meridian paths(LHRCMs)in mini-pig,we aimed to detect the low hydraulic resistance point(LHRP)and display the LHRCMs in rats.Methods:A technique for measuring interstitial hydraulic resistance(Rh)in rats was established to detect and measure the Rh along the conception vessel(CV)in TCM,and Alcian Blue(AB)solution was injected into the LHRP along the CV.The interstitial fluid pressure(IFP)of the LHRP was measured before and after AB injection.Then,the distribution characteristics of the AB solution were investigated to explore the relationship between AB tracks and meridian paths in TCM.Results:The positions of the LHRPs coincided with the low impedance points(LIPs)of the rat skin along the CV.The Rh value along the CV(10.37,1.26,×10^(6)dyne s cm^(-5))was significantly lower than that in the non-meridian area(19.13±1.37,×10^(6)dyne s cm^(-5),P<0.01).After AB injection,the IFP of the LHRP was 2.52 mmHg,which was higher than that before AB injection.The AB tracks(ABT)along the CV,spleen meridian,and kidney meridian appeared in one or two directions,with single or multiple paths and uneven thickness and length.The appearance rate was 73.33%.Conclusions:LHRCMs existed not only in minipigs but also in rats.The LHRCMs could be observed after AB injection into the LHRP in the subcutaneous connective tissues of rats.展开更多
The common acupoints and meridians for gynecology as well as their biophysical characteristics were summarized,the importance of biophysical characteristics for common meridians and acupoints were pointed out,some new...The common acupoints and meridians for gynecology as well as their biophysical characteristics were summarized,the importance of biophysical characteristics for common meridians and acupoints were pointed out,some new research fields for fundamental study on common acupoints in gynecology were put forward,such as proteomics,genomics,transcriptomics,and other fields,and further evidence support for large-sample randomized controlled trials were appealed.展开更多
Objective To observe the clinical efficacy of auricular subcutaneous penetration needling combining with row acupuncture at meridian sinew on prolapse of lumbar intervertebral disc. Methods One hundred and three patie...Objective To observe the clinical efficacy of auricular subcutaneous penetration needling combining with row acupuncture at meridian sinew on prolapse of lumbar intervertebral disc. Methods One hundred and three patients with prolapse of lumbar intervertebral disc were treated with a combined treatment of auricular subcutaneous penetration needling and row acupuncture at meridian sinew. Results Of 103 patients, 46 cases were cured, 33 were markedly effective, 21 effective and 3 ineffective. The total effective rate was 97.1% （100/103）. Conclusion The combined treatment of auricular subcutaneous penetration needling and row acupuncture at meridian sinew has a significant efficacy for the treatment of prolapse of lumbar intervertebral disc.展开更多
Based on the Chinese Meridian Project(CMP),the International Meridian Circle Program(IMCP)aims to coordinate the deployment of a comprehensive ground-based monitoring network along the 120°E-60°W Great Merid...Based on the Chinese Meridian Project(CMP),the International Meridian Circle Program(IMCP)aims to coordinate the deployment of a comprehensive ground-based monitoring network along the 120°E-60°W Great Meridian Circle to track the propagation and evolution of space weather events from the Sun to the Earth,as well as the imprints of other major natural and anthropic hazards on the ionosphere,the middle and upper atmosphere.Currently,we have completed the IMCP headquarters building in Beijing and established the China-Brazil Joint Laboratory for Space Weather in cooperation with Brazil.Meanwhile,the Chinese Meridian Project PhaseⅡand different components of the IMCP observation system are under construction.展开更多
Deep venous thrombosis of lower extremity is one of the common complications in orthopedic perioperative period.It is caused by many factors,such as peripheral vein dilation,slow blood flow;long-term immobilization,be...Deep venous thrombosis of lower extremity is one of the common complications in orthopedic perioperative period.It is caused by many factors,such as peripheral vein dilation,slow blood flow;long-term immobilization,bed rest and so on.On the one hand,it affects the early postoperative functional exercise and functional recovery,on the other hand,it increases the length of hospital stay and economic burden,increases the pain of patients and even endangers their lives.Effective treatment of traditional Chinese medicine combined with western medicine can play a better role in the prevention and treatment of lower extremity deep venous thrombosis.This study expounds the concept of spleen and stomach meridians in the prevention and treatment of lower extremity deep venous thrombosis,and puts forward some opinions on the dialectical treatment and daily conditioning of lower extremity deep venous thrombosis,hoping to provide ideas for the clinical prevention and treatment of lower extremity deep venous thrombosis in traditional Chinese medicine.展开更多
In 2024,the Chinese Meridian Project(CMP)completed its construction,deploying 282 instruments across 31 stations.This achievement not only provides a robust foundation but also serves as a reference template for the I...In 2024,the Chinese Meridian Project(CMP)completed its construction,deploying 282 instruments across 31 stations.This achievement not only provides a robust foundation but also serves as a reference template for the International Meridian Circle Program(IMCP).The IMCP aims to integrate and establish a comprehensive network of ground-based monitoring stations designed to track the propagation of space weather events from the Sun to Earth.Additionally,it monitors various disturbances generated within the Earth system that impact geospace.Over the past two years,significant progress has been made on the IMCP.In particular,the second phase of construction for the China-Brazil Joint Laboratory for Space Weather has been completed,and the North Pole and Southeast Asia networks are under active construction.The 2024 IMCP joint observation campaign was successfully conducted.To facilitate these developments,the scientific program committee of IMCP was established,following the success of 2023 IMCP workshop and the space weather school,which was co-hosted with the Asia-Pacific Space Cooperation Organization(APSCO)and sponsored by Chinese Academy of Sciences(CAS)and Scientific Committee on Solar-Terrestrial Physics(SCOSTEP).Preparations are now underway for the 2024 workshop in collaboration with the National Institute for Space Research(INPE)in Brazil.展开更多
Objective To explore the effect of meridian sinew row needling combined with dermal needling on spasticity of post-stroke patients with upper limb hemiparalysis. Methods Four hundred and eighty-eight cases of post-str...Objective To explore the effect of meridian sinew row needling combined with dermal needling on spasticity of post-stroke patients with upper limb hemiparalysis. Methods Four hundred and eighty-eight cases of post-stroke patients with upper limb spasticity were randomly divided into two groups at the ratio of 1： 1, the group of meridian sinew row needling combined with dermal needling （group A, 244 cases） and western medication group （group B, 244 cases）. Coupled with rehabilitation, the patients in the group A were given meridian sinew row needling combined with dermal needling where five shu points were specifically selected, and three yang meridians of the hand were treated with acupuncture with muscle region, and three yin meridians of the hand were treated with dermal needles; the patients in the group B was treated with conventional western medication with piracetam injection and cerebroprotein hydrolysate included. Clinical efficacy was evaluated among patients in the two groups after three weeks of continuous treatment, and upper limb spasticity and motor functions were observed through modified Asworth Scale and FugI-Meyer Assessment Scale （FMA） before and after treatment. Results For Asworth Scale, group A was significantly superior to group B （3.04 ± 1.29 vs 3.88 ± 1.54, P〈0.05）; for FMA scale, group A was also significantly superior to group B （48.67± 15.64 vs 42.96±14.72, P〈0.05）; mitigations of motor status of upper limb joints in group A, such as remission of shoulder adduction （90.5%）, pronation of forearm （70.7%）, elbow joint flexion （73.1%）, wrist joint flexion （80.9%） and finger flexion （88.1%）, were superior to those of group B （70.0%, 60.0%, 61.9%, 57.4%, 63.2%, all P〈0.05）. Conclusion Good clinical efficacy of the treatment with combined with dermal needling on spasticity of post-stroke patients with upper limb hemiparalysis is achieved.展开更多
基金Supported by Zhejiang Province Traditional Chinese Medicine Science and Technology Plan Project,No.2023ZL230。
文摘BACKGROUND Although gastroscopy is a commonly used diagnostic and therapeutic technique,postoperative gastrointestinal dysfunction is prone to occur.Traditional Chinese medicine theory suggests that postoperative gastrointestinal disorders are related to spleen and stomach weakness.This study hypothesizes that the combination of acupoint application at the Ziwu Liuzhu acupoint and percutaneous acupoint electrical stimulation can promote postoperative gastrointestinal function recovery and alleviate stress reactions.AIM To investigate the effects of acupoint application of Ziwu Liuzhu combined with percutaneous acupoint electrical stimulation on postoperative gastrointestinal function recovery and stress response in patients undergoing gastrointestinal endoscopy surgery.METHODS A total of 120 patients who underwent gastroscopy surgery were selected and treated between October 2024 and January 2025.This study used a stratified block randomization method,and then allocated groups using computer-generated random number sequences(SAS 9.4 software).The groups were divided into two groups:A control group of 60 patients who received routine postoperative intervention measures,and an observation group of 60 patients who received acupuncture point application combined with transcutaneous acupoint electrical CONCLUSION The combination of percutaneous acupoint electrical stimulation in gastroscopy patients has been demonstrated to be both highly safe and effective.The benefits of this approach include the promotion of postoperative gastrointestinal function,the reduction of stress response,the attainment of optimal results,and the enhancement of patient satisfaction.
文摘OBJECTIVE:To evaluate the effects of external application of warm meridian medicated wine and polarized light therapy combined with acupuncture on pain management following vertebroplasty. METHODS:A total of 120 patients with osteoporotic vertebral compression fractures treated by vertebroplasty at our hospital were divided into four groups. The control group received non-steroidal anti-inflammatory drugs, the Treatment Group Ⅰ received acupuncture alone, Treatment Group Ⅱ was treated with medicated wine for warming meridians alongside polarized light physiotherapy, and Treatment Group Ⅲ received a combination of medicated wine for warming meridians, polarized light therapy, and acupuncture. The clinical efficacy, pain thresholds at various time points, temperature pain threshold, electric pain threshold, quality of life, sleep quality index, lumbar dysfunction index, visual analog scale(VAS) scores, and incidence of adverse reactions were compared and analyzed across the four groups. RESULTS:The total clinical effective rate in Treatment Group Ⅲ was significantly higher than that in the control group, Treatment Group Ⅰ, and Treatment Group Ⅱ(P < 0.05). At 24 and 72 h post-treatment, the VAS scores, temperature pain thresholds, and electric pain thresholds in Treatment Group Ⅲ were significantly lower than those in the control group, Treatment Group Ⅰ, and Treatment Group Ⅱ(P < 0.05). Additionally, quality-of-life scores in Treatment Group Ⅲ were markedly higher compared to the control group, Treatment Group Ⅰ, and Treatment Group Ⅱ, while the Pittsburgh Sleep Quality Index scores, Oswestry Disability Index scores, and incidence of adverse reactions in Treatment Group Ⅲ were significantly lower than in the other groups(P < 0.05). CONCLUSION:The external application of warm meridian medicated wine and polarized light therapy combined with acupuncture significantly reduces postoperative pain following vertebroplasty, enhances lumbar function, and improves both sleep quality and overall quality of life for patients. This approach is recommended for clinical application.
文摘Objective:To study the clinical efficacy of applying the Meridian Flow Low-Frequency Therapy Device combined with Chinese herbal enema for patients with acute and chronic pelvic inflammatory disease(PID).Methods:Sixty-two patients with acute and chronic PID admitted from January 2024 to October 2025 were selected and randomly divided into a standard group(n=31)and an experimental group(n=31).The standard group received conventional medication+Chinese herbal enema treatment.The experimental group received the Meridian Flow Low-Frequency Therapy Device in addition to the standard group’s treatment.The clinical efficacy,changes in inflammatory markers,and pelvic improvement were compared between the two groups.Results:The excellent-good rate of treatment in the experimental group was higher than that in the standard group(p<0.05).The levels of various inflammatory factors in the experimental group were lower than those in the standard group(all p<0.05).The improvement in pelvic mass diameter and pelvic effusion depth in the experimental group was superior to that in the standard group(both p<0.05).Conclusion:The Meridian Flow Low-Frequency Therapy Device combined with Chinese herbal enema has a definite curative effect in treating pelvic inflammatory disease.It can effectively alleviate clinical symptoms,reduce inflammatory response,and promote the improvement of the pelvic environment.
基金Supported by the Natural Science Foundation of Jiangxi Province (No :2008 GZY0022)the Technology Plan of Jiangxi Provincial Department of Education (No :GJJ09280)
文摘Objective To study the effect of the serum derived from the rats treated with electroacupunctre at Stomach Meridian acupoints on the EGFR signal transduction pathway in gastric mucosal cells. Methods Sixty rats were randomly divided into 5 groups： model group, Stomach （ST） Meridian group, Gallbladder （GB） Meridian group, ST＋ PD153035 group and GB＋ PD153035 group. Water-immersion and restrained stress method was adopted for preparation of the stress-induced gastric ulcer rat model, and the gastric mucosa cells were separated by using pronase digestion method. Gastric mucosa cells were incubated respectively with PD153035, EGFR inhibitor and the serum; PLCγ-1＇s expression level in gastric mucosa cells was tested by enzyme-linked immunosorbant assay （ELISA）, and PKC activity by isotope mingling method; and reverse transcription polymerase chain reaction assay （RT-PCR） was used for testing expression level of c-myc gene. Results The expression levels of PLCγ-1 ,PKC and c- myc gene were lower in gastric mucosa cells in the model group; there were relatively high expression levels of PLCγ-1 ,PKC and c-myc gene in the ST Meridian group and the GB Meridian group, with the highest expression levels of PLCγ-1 ,PKC and c-myc gene in the ST Meridian, and with a significant difference between the ST Meridian group and the GB Meridian group （P〈0.01 ） ; and relative lower expression levels of PLCγ-1, PKC and c-myc gene were seen in the ST ＋ PD153035 group and the GB ＋ PD153035 group; and there was a significant difference between the ST Meridian group and the ST ＋ PD153035 group （P〈0.01）. Conclusion There was a close correlation between the healing effect of electroacupuncture and activation of the EGFR signal transduction pathway in the impaired gastric mucosa cells, which was also one proof for the TCM theory： ＂There is relative specificity between the meridians and viscera＂.
文摘Objective To compare the clinical therapeutic effects on scapulohumeral periarthritis between kinetic acupuncture on the distal points of the affected meridians and shoulder three-needle therapy.Methods Fifty cases of scapulohumeral periarthritis were randomly divided into an observation group and a control group,25 cases for each.The cases in observation group were treated with kinetic acupuncture on the distal points of the affected meridians.For example,the case of Hand-Taiyin type was treated with Yújì （鱼际 LU 10） and the case of Hand-Yangming type was treated with Hégǔ （合谷 LI 4）,etc.The cases in control group were treated with shoulder three-needle therapy,in which,Jiānqián （肩前 Extral）,Jiānyú （肩髃 LI 15） and Jiānliáo （肩髎 TE 14） were selected;7 days of treatment made one session,totally 2 sessions were required.Results In observation group,the curative rate based on ROM of shoulder joint was 72.0% （18/25）,which was superior to that of 40.0% （10/25） in control group （P0.05）.After treatment,the improvements of McGill SF-MPQ score,VAS and PPI in observation group were all superior to those in control group （all P0.05）.Conclusion The kinetic acupuncture on the distal points of the affected meridians is advantageous at analgesia and motor improvements of shoulder joint in treatment of scapulohumeral periarthritis as compared with shoulder three-needle therapy.
基金the National Natural Science Foundation of China, No.30973720the Science Research Foundation of Ministry of Health & United Fujian Provincial Health and Education Project for Tackling the Key Research of China, No.WKJ2005-2-004
文摘The peripheral driver stimulating theory states that as a driver passes along a certain meridian during acupuncture; the driver provokes nerve sense devices along the meridian, resulting in the nerve impulse entering the central nervous system. Accordingly, volunteers have reported propagated sensations along the meridians （PSM）. The present study was designed to utilize a cortical somatosensory-evoked potential （CSEP） topographic map for determining whether stimulation expansion occurs in somatosensory area I when sensation was provoked in individuals with obvious PSM. The sensation was blocked by mechanical compression, and the sensation was imitated in individuals without PSM. Results revealed a red, high-potential signal in the representative area of the lower limbs in individuals with obvious PSM symptoms when the Gall Bladder Meridian （GBM） sensation passed to the head and face. This representative area was near the middle line of the CSEP topographic map, and a red, high-potential signal, which jumps over the representative area of the upper limbs, also appeared in the representative face area, which was at the external region of the CSEP topographic map. However, in individuals exhibiting no PSM, only a red high-potential signal appeared in the representative lower limb area. When Hegu （LI 4） was stimulated in individuals without PSM, an obvious evoked response appeared only in the representative upper limb area. However, when Hegu was stimulated in individuals exhibiting PSM, the response area was larger in the representative upper limb area and extended to the representative face area. When Guangrning （GB 37） was stimulated in PSM individuals, the face representation response disappeared and was confined to a foot representation of the somatosensory area I when PSM was blocked by mechanical pressure. Results suggested that mechanical compression blocked PSM, and corresponding changes were exhibited in the CSEP topographic map. These results provide compelling evidence for the hypothesis that peripheral driver stimulation is the key element in producing PSM.
基金supported by grants from National Natural Science Foundation of China (No .90209009)National Basic Research Program(No .2006CB504502)~~
文摘Objective To explore the relationship between connexin 43 and acupoints and meridians. Methods we detected one major skin gap junction connexin （connexin43, Cx43） in meridians and acupoints, and studied the expression of Cx43 in Zusanli （足三里 ST 36） acupoints compared with control non-acupoint regions in rats after acupuncture treatments. The expression of Cx43 was detected by using immunohisto- chemistry, immunoblotting, and RT-PCR for Cx43 protein and mRNA level. Results The results showed much more abundant Cx43 expression in some cells in the skin and subcutaneous tissue of rat at ST 36 acupoints and bladder and kidney meridians than that of in the controls. The mRNA and protein levels of Cx43 in acupoints were significantly higher than those of in the control points in non-acupuncture groups and even more so after acupuncture treatments. Conclusion Our research implied that connexins and gap junctions could have a close relationship to acupoints and meridians, and gap junctional intercellular communication might play an important role in the effect of acupuncture.
文摘Objective To compare differences in therapeutic effects between acupuncture accelerating qi-flow along meridians （AQF） and conventional acupuncture （CA） in treating periarthritis of shoulder to find better acupuncture methods. Methods Sixty-four patients were randomly divided into two groups： group AQF, and group CA with 32 cases in each group. Jiānyú （肩髃 LI 15）, Jiānliáo （肩髎 TE 14）, Jiānzhēn （肩贞 SI 9）, Bìnào （臂臑 LI 14）, Qūchí （曲池 LI 11） and Wàiguān （外关 TE 5） on the affected side were used in both groups, and the two acupuncture methods were respectively used in the two groups for consecutive 2 courses. Pain and moving functions of shoulder and ability in daily life （ADL） were used as indices for evaluating therapeutic effects. Results The total effective rate was 96.9% （31/32） and 81.3% （26/32） in group AQF and group CA, respectively, showing superiority of AQF to CA （P〈0.05）. Scores reflecting pain and moving functions of shoulder and ADL were all improved after treatment in both groups （all P〈0.05）, and the improvement in group AQF was more obvious than those in group CA （all P〈0.05）. Conclusion In treating periarthritis of shoulder, the acupuncture accelerating qi-flow along meridians was better than conventional acupuncture in alleviating pain of the shoulder, improving its moving function and elevating abilities in daily life.
基金Supported by Beijing Municipal Science and Technology Commission(Z181100002918001)。
文摘The Earth is buffered from the ferocious onslaught of the solar wind by a thin layer of matter known as the atmosphere and geospace.This layer absorbs energy from irradiance and outburst from the Sun,as well as from disasters,transient phenomena and anthropogenic emissions originated from Earth.Through complicated physics,the absorbed energy changes the atmospheric and geospace state and sometimes gets re-released to power extreme events such as space weather.Taking place globally,these complicated processes cannot be understood unless they are studied globally.The Chinese scientists have proposed the International Meridian Circle Program(IMCP)to meet this demand.By operating nearly 1000 instruments encompassing all latitudes along with the 120°E–60°W longitudes,IMCP aims,for the first time,to construct comprehensive 3D data representation of the atmosphere and geospace on a global scale and empower interdisciplinary research to tackle key questions related to Earth’s environment and climate change.
文摘Through study on articles of fMRI and acupuncture-moxibustion of the recent 10 years, application of fMRI on specificity studies of meridians and acupoints such as comparison of single acupoint, point group, various manipulations, essence of needling sensation and indications of acupuncture, etc. were summarized. And it is held that the future study should be focused on the entire meridian. The principle of the relationship among meridians, the centre nerve and Zang-fu organs should be explored as well at a new level so as to promote the further studies on essence of meridian.
基金Supported by National Program on Key Basic Research Project (973 Program): 2010 CB 530506
文摘The status quo of study on specificity of meridian acupoints is summarized in this article through retrieval of relative literatures published in the recent 10 years in databases such as CNKI and SCI. The result indicates that specificity, which is brought into play through the inner biological mechanism, can be found in meridian acupoint efficacy. However, problems still remain since studies at present are still not systematic, comprehensive and scientific. In the future, relative studies should be carried out on extensive diseases and disease models with modern scientific technologies and equipments, strict as well as scientific experimental designation and evaluation methods.
基金the Fundamental Research Funds for the Central Public Welfare Research Institutes:ZZ 20191606National Natural Science Foundation of China:82050006。
文摘Background:Continuous and porous low hydraulic resistance channels(LHRCs)are important structures of meridians in traditional Chinese medicine(TCM).In this study,based on the previous research on LHRCs along meridian paths(LHRCMs)in mini-pig,we aimed to detect the low hydraulic resistance point(LHRP)and display the LHRCMs in rats.Methods:A technique for measuring interstitial hydraulic resistance(Rh)in rats was established to detect and measure the Rh along the conception vessel(CV)in TCM,and Alcian Blue(AB)solution was injected into the LHRP along the CV.The interstitial fluid pressure(IFP)of the LHRP was measured before and after AB injection.Then,the distribution characteristics of the AB solution were investigated to explore the relationship between AB tracks and meridian paths in TCM.Results:The positions of the LHRPs coincided with the low impedance points(LIPs)of the rat skin along the CV.The Rh value along the CV(10.37,1.26,×10^(6)dyne s cm^(-5))was significantly lower than that in the non-meridian area(19.13±1.37,×10^(6)dyne s cm^(-5),P<0.01).After AB injection,the IFP of the LHRP was 2.52 mmHg,which was higher than that before AB injection.The AB tracks(ABT)along the CV,spleen meridian,and kidney meridian appeared in one or two directions,with single or multiple paths and uneven thickness and length.The appearance rate was 73.33%.Conclusions:LHRCMs existed not only in minipigs but also in rats.The LHRCMs could be observed after AB injection into the LHRP in the subcutaneous connective tissues of rats.
文摘The common acupoints and meridians for gynecology as well as their biophysical characteristics were summarized,the importance of biophysical characteristics for common meridians and acupoints were pointed out,some new research fields for fundamental study on common acupoints in gynecology were put forward,such as proteomics,genomics,transcriptomics,and other fields,and further evidence support for large-sample randomized controlled trials were appealed.
文摘Objective To observe the clinical efficacy of auricular subcutaneous penetration needling combining with row acupuncture at meridian sinew on prolapse of lumbar intervertebral disc. Methods One hundred and three patients with prolapse of lumbar intervertebral disc were treated with a combined treatment of auricular subcutaneous penetration needling and row acupuncture at meridian sinew. Results Of 103 patients, 46 cases were cured, 33 were markedly effective, 21 effective and 3 ineffective. The total effective rate was 97.1% （100/103）. Conclusion The combined treatment of auricular subcutaneous penetration needling and row acupuncture at meridian sinew has a significant efficacy for the treatment of prolapse of lumbar intervertebral disc.
基金Supported by the International Partnership Program of Chinese Academy of Sciences(183311KYSB20200003)。
文摘Based on the Chinese Meridian Project(CMP),the International Meridian Circle Program(IMCP)aims to coordinate the deployment of a comprehensive ground-based monitoring network along the 120°E-60°W Great Meridian Circle to track the propagation and evolution of space weather events from the Sun to the Earth,as well as the imprints of other major natural and anthropic hazards on the ionosphere,the middle and upper atmosphere.Currently,we have completed the IMCP headquarters building in Beijing and established the China-Brazil Joint Laboratory for Space Weather in cooperation with Brazil.Meanwhile,the Chinese Meridian Project PhaseⅡand different components of the IMCP observation system are under construction.
文摘Deep venous thrombosis of lower extremity is one of the common complications in orthopedic perioperative period.It is caused by many factors,such as peripheral vein dilation,slow blood flow;long-term immobilization,bed rest and so on.On the one hand,it affects the early postoperative functional exercise and functional recovery,on the other hand,it increases the length of hospital stay and economic burden,increases the pain of patients and even endangers their lives.Effective treatment of traditional Chinese medicine combined with western medicine can play a better role in the prevention and treatment of lower extremity deep venous thrombosis.This study expounds the concept of spleen and stomach meridians in the prevention and treatment of lower extremity deep venous thrombosis,and puts forward some opinions on the dialectical treatment and daily conditioning of lower extremity deep venous thrombosis,hoping to provide ideas for the clinical prevention and treatment of lower extremity deep venous thrombosis in traditional Chinese medicine.
基金Supported by International Meridian Circle Program Headquarters,China-Brazil Joint Laboratory for Space Weather(Y42347A99S)。
文摘In 2024,the Chinese Meridian Project(CMP)completed its construction,deploying 282 instruments across 31 stations.This achievement not only provides a robust foundation but also serves as a reference template for the International Meridian Circle Program(IMCP).The IMCP aims to integrate and establish a comprehensive network of ground-based monitoring stations designed to track the propagation of space weather events from the Sun to Earth.Additionally,it monitors various disturbances generated within the Earth system that impact geospace.Over the past two years,significant progress has been made on the IMCP.In particular,the second phase of construction for the China-Brazil Joint Laboratory for Space Weather has been completed,and the North Pole and Southeast Asia networks are under active construction.The 2024 IMCP joint observation campaign was successfully conducted.To facilitate these developments,the scientific program committee of IMCP was established,following the success of 2023 IMCP workshop and the space weather school,which was co-hosted with the Asia-Pacific Space Cooperation Organization(APSCO)and sponsored by Chinese Academy of Sciences(CAS)and Scientific Committee on Solar-Terrestrial Physics(SCOSTEP).Preparations are now underway for the 2024 workshop in collaboration with the National Institute for Space Research(INPE)in Brazil.
基金Supported by Hebei Administration of Traditional Chinese Medicine(2009180)
文摘Objective To explore the effect of meridian sinew row needling combined with dermal needling on spasticity of post-stroke patients with upper limb hemiparalysis. Methods Four hundred and eighty-eight cases of post-stroke patients with upper limb spasticity were randomly divided into two groups at the ratio of 1： 1, the group of meridian sinew row needling combined with dermal needling （group A, 244 cases） and western medication group （group B, 244 cases）. Coupled with rehabilitation, the patients in the group A were given meridian sinew row needling combined with dermal needling where five shu points were specifically selected, and three yang meridians of the hand were treated with acupuncture with muscle region, and three yin meridians of the hand were treated with dermal needles; the patients in the group B was treated with conventional western medication with piracetam injection and cerebroprotein hydrolysate included. Clinical efficacy was evaluated among patients in the two groups after three weeks of continuous treatment, and upper limb spasticity and motor functions were observed through modified Asworth Scale and FugI-Meyer Assessment Scale （FMA） before and after treatment. Results For Asworth Scale, group A was significantly superior to group B （3.04 ± 1.29 vs 3.88 ± 1.54, P〈0.05）; for FMA scale, group A was also significantly superior to group B （48.67± 15.64 vs 42.96±14.72, P〈0.05）; mitigations of motor status of upper limb joints in group A, such as remission of shoulder adduction （90.5%）, pronation of forearm （70.7%）, elbow joint flexion （73.1%）, wrist joint flexion （80.9%） and finger flexion （88.1%）, were superior to those of group B （70.0%, 60.0%, 61.9%, 57.4%, 63.2%, all P〈0.05）. Conclusion Good clinical efficacy of the treatment with combined with dermal needling on spasticity of post-stroke patients with upper limb hemiparalysis is achieved.
