In this research, Lysolecithin-a substance made with 100% natural ingredients - was given to ICR mice as medication to measure its periodic effect on the noradrenalin (NA), dopamine (DA), and serotonin (5-HT) levels o...In this research, Lysolecithin-a substance made with 100% natural ingredients - was given to ICR mice as medication to measure its periodic effect on the noradrenalin (NA), dopamine (DA), and serotonin (5-HT) levels of the brain. Both ICR and SAM mice were separated into two groups - control group and Lysolecithin (K. Lysolecithin: hydrolytic lysolecithin) medicated group, and given 1-week preparation period. The K. Lysolecithin group was given 500mg/kg of K. Lysolecithin at 0.2mL per dosage for 4 weeks, and the control group was given the same amount of dosage of water during the same period. NA, DA and 5-HT concentrations were measured from the blood before medication and 8 weeks / 12 weeks / 16 weeks after the first medication. For the SAM mice, 8 weeks after they were medicated with K .Lysolecithin, Morris Water Maze Test was conducted for 7 consecutive days and then the concentrations were measured by drawing blood from the heart. The K. Lysolecithin medicated group showed a tendency to have a statistically significant higher concentrations of 5-HT and NA in the blood. Also, periodic examination showed that the monoamine levels were highest in the 12th week and declined thereafter.展开更多
An 8-week trial was conducted to investigate graded levels of dietary LPC on growth,apparent digestibility(ADs)of nutrients and lipid metabolism in juvenile turbot Scophthalmus maximus L.Five experimental diets were f...An 8-week trial was conducted to investigate graded levels of dietary LPC on growth,apparent digestibility(ADs)of nutrients and lipid metabolism in juvenile turbot Scophthalmus maximus L.Five experimental diets were formulated which contain 11%crude fat with graded amounts of LPC(0,1000,2500,4000,5500 mg/kg diet).The fish fed diet with 11%crude lipid and 0 LPC was used as the negative control group(C-),meanwhile the fish fed diet with 12%crude fat and 0 LPC was used as the positive control group(C+).Each diet was fed to triplicate groups of turbot(initial body weight of 41 g)for 56d.Weight gain rate and specific growth rate of the fish fed LPC supplemented diets were significantly higher than the control groups,and the growth performance of the C-group was significantly lower than the others.The viscerosomatic index(VSI)was significantly decreased and the gall bladder somatic index(GSI)was significantly increased by dietary LPC.Crude lipid contents of muscle were elevated by dietary LPC.Apparent digestibility of energy was decreased by dietary LPC,but protein and lipid were not affected.Both total cholesterol(T-CHO)and high density lipoprotein cholesterol(HDL-C)were up-regulated,meanwhile neither alanine aminotransferase(ALT)nor total protein(TP)were down-regulated by dietary LPC.Enzymes involved in lipid metabolism(total lipase,hepatic lipase,lipoprotein lipase,fatty acids synthase,and lipase)were all elevated by dietary LPC.In conclusion,the lipid requirements of turbot were decreased by dietary LPC and the lipid utilization coefficient was enhanced.Based on SAS NLIN regression,dietary 870.37 mg/kg LPC was appropriate for turbot juvenile.展开更多
文摘In this research, Lysolecithin-a substance made with 100% natural ingredients - was given to ICR mice as medication to measure its periodic effect on the noradrenalin (NA), dopamine (DA), and serotonin (5-HT) levels of the brain. Both ICR and SAM mice were separated into two groups - control group and Lysolecithin (K. Lysolecithin: hydrolytic lysolecithin) medicated group, and given 1-week preparation period. The K. Lysolecithin group was given 500mg/kg of K. Lysolecithin at 0.2mL per dosage for 4 weeks, and the control group was given the same amount of dosage of water during the same period. NA, DA and 5-HT concentrations were measured from the blood before medication and 8 weeks / 12 weeks / 16 weeks after the first medication. For the SAM mice, 8 weeks after they were medicated with K .Lysolecithin, Morris Water Maze Test was conducted for 7 consecutive days and then the concentrations were measured by drawing blood from the heart. The K. Lysolecithin medicated group showed a tendency to have a statistically significant higher concentrations of 5-HT and NA in the blood. Also, periodic examination showed that the monoamine levels were highest in the 12th week and declined thereafter.
基金We all thank Kemin Industries(Zhuhai)Co.Ltd for supplying LPC and supporting many advices for the trial.The work was supported by key research and development Plan of Shandong Province(2016GSF115005)Technology Development Plan Project of Shandong Province(2014GHY115006).
文摘An 8-week trial was conducted to investigate graded levels of dietary LPC on growth,apparent digestibility(ADs)of nutrients and lipid metabolism in juvenile turbot Scophthalmus maximus L.Five experimental diets were formulated which contain 11%crude fat with graded amounts of LPC(0,1000,2500,4000,5500 mg/kg diet).The fish fed diet with 11%crude lipid and 0 LPC was used as the negative control group(C-),meanwhile the fish fed diet with 12%crude fat and 0 LPC was used as the positive control group(C+).Each diet was fed to triplicate groups of turbot(initial body weight of 41 g)for 56d.Weight gain rate and specific growth rate of the fish fed LPC supplemented diets were significantly higher than the control groups,and the growth performance of the C-group was significantly lower than the others.The viscerosomatic index(VSI)was significantly decreased and the gall bladder somatic index(GSI)was significantly increased by dietary LPC.Crude lipid contents of muscle were elevated by dietary LPC.Apparent digestibility of energy was decreased by dietary LPC,but protein and lipid were not affected.Both total cholesterol(T-CHO)and high density lipoprotein cholesterol(HDL-C)were up-regulated,meanwhile neither alanine aminotransferase(ALT)nor total protein(TP)were down-regulated by dietary LPC.Enzymes involved in lipid metabolism(total lipase,hepatic lipase,lipoprotein lipase,fatty acids synthase,and lipase)were all elevated by dietary LPC.In conclusion,the lipid requirements of turbot were decreased by dietary LPC and the lipid utilization coefficient was enhanced.Based on SAS NLIN regression,dietary 870.37 mg/kg LPC was appropriate for turbot juvenile.
