Aesthetic value,scientific research value and ecological protection value of world heritage in Mount Longhu,Jiangxi Province was analyzed.And the urgency of protecting Danxia landform was clarified from the perspectiv...Aesthetic value,scientific research value and ecological protection value of world heritage in Mount Longhu,Jiangxi Province was analyzed.And the urgency of protecting Danxia landform was clarified from the perspective of influence brought by tourism development,population explosion,economic development and natural disasters.Planning and management agencies and relevant policy support for the safeguarding of world heritage in Mount Longhu,Jiangxi Province were expounded,as well as protective strategies for different zones and grades according to their scientific research value and protection value.Training for the protection and management of Mount Longhu,and local residents' participation in the training were introduced.Finally,suggestions for the heritage protection in Mount Longhu were given:project construction and management should be stressed,operation activities standardized,ticket management for the Longhu World Heritage improved,and the sustainable development persisted in.展开更多
After analyzing three misunderstandings about eco-tourism development,the paper pointed out that low-carbon tourism based on control of carbon emission had larger implementation space,which could be applied in all typ...After analyzing three misunderstandings about eco-tourism development,the paper pointed out that low-carbon tourism based on control of carbon emission had larger implementation space,which could be applied in all types of tourist destinations,with strong operability and the effectiveness evaluation of which was easier to be quantized.On this basis,low-carbon development thought of nature reserve was proposed by taking Guangxi Longhu Mountain Nature Reserve as the example.Through introduction of general situation of low-carbon tourist resources in Longhu Mountain,it analyzed necessity to design low-carbon tourist products in Longhu Mountain Nature Reserve,designed low-carbon tourist activities according to resources characteristics,and proposed five distinctive low-carbon tour routes in light with different tourists markets.Finally,some relevant suggestions on development had been put forward.展开更多
In view of lake scenic areas with abundant tourist resources but less-developed economy,contradictions between the urgency of its tourist resource development and complexity of urban-rural planning compilation were an...In view of lake scenic areas with abundant tourist resources but less-developed economy,contradictions between the urgency of its tourist resource development and complexity of urban-rural planning compilation were analyzed,and also limitations summarized as insufficient time and fund.Statutory planning contents included in the integrated compilation system were elaborated,and compilation of the integrated planning for the Longhe Lake Scenic Area in the Taihang Mountains was taken for example to introduce planning concepts of the compilation technical system.Considering characteristics of the study area,"regionality" was stressed as the foundation of planning compilation,concise,convenient and practical planning compilation contents were advocated and further explained from the perspectives of compiling by layer and category.In view of this,it is necessary to apply integrated compilation mode under certain circumstances,so as to provide a new approach for the planning compilation of other regions in China and enhance economic and social development of local areas.展开更多
Declaration of competing interest statement was not included in the published version.The appropriate declaration of competing interest statement,provided by the authors,is included below.Declaration of competing inte...Declaration of competing interest statement was not included in the published version.The appropriate declaration of competing interest statement,provided by the authors,is included below.Declaration of competing interest:The authors declare the following financial interests/personal relationships which may be considered as potential competing interests:Jiahua Jin,Liqin Ding,and Biye Wang are employed by the Shanghai Zhonghua Pharmaceutical Co.,Ltd.展开更多
Background and aim:Liver fibrosis resulting from persistent liver injury represents a major healthcare problem globally.Traditional Chinese medicine has played an essential role in the treatment of liver fibrosis in r...Background and aim:Liver fibrosis resulting from persistent liver injury represents a major healthcare problem globally.Traditional Chinese medicine has played an essential role in the treatment of liver fibrosis in recent years.Thus,this study aims to assess the effect of Longhu Rendan(LHRD),a Chinese traditional patent medicine,on liver fibrosis and its potential mechanism.Methods:The liver fibrosis in mice was induced via the intraperitoneal injection of carbon tetrachloride(CCl4)for 6 weeks or bile duct ligation for 15 days.Various methods were used to judge the therapeutic effect of LHRD.Results:LHRD significantly suppressed the activity of serum index of abnormal liver function,liver cell apoptosis,and necrosis,attenuating liver injury.Moreover,LHRD treatment alleviated liver fibrotic features,such as the reduction of collagen deposition and hepatic stellate cell activation as well as profibrotic gene expression.Mechanistically,LHRD treatment inhibited nuclear transcription factorkappa B signaling and inflammatory gene expression and diminished the production of reactive oxygen species and 4-hydroxynonenal,along with the downregulation of NADPH oxidase 4.Conclusions:Overall,the present study demonstrates that LHRD ameliorates liver injury and fibrosis via the inhibition of inflammation and oxidative stress in mice,indicating that LHRD is a potential medicine for the treatment of liver fibrosis.展开更多
文摘Aesthetic value,scientific research value and ecological protection value of world heritage in Mount Longhu,Jiangxi Province was analyzed.And the urgency of protecting Danxia landform was clarified from the perspective of influence brought by tourism development,population explosion,economic development and natural disasters.Planning and management agencies and relevant policy support for the safeguarding of world heritage in Mount Longhu,Jiangxi Province were expounded,as well as protective strategies for different zones and grades according to their scientific research value and protection value.Training for the protection and management of Mount Longhu,and local residents' participation in the training were introduced.Finally,suggestions for the heritage protection in Mount Longhu were given:project construction and management should be stressed,operation activities standardized,ticket management for the Longhu World Heritage improved,and the sustainable development persisted in.
基金Supported by Scientific Research Item of Education Department of Guangxi Province in2010(201010LX282)Teaching Reform Project of Guangxi Teachers Education University from 2010 to 2011~~
文摘After analyzing three misunderstandings about eco-tourism development,the paper pointed out that low-carbon tourism based on control of carbon emission had larger implementation space,which could be applied in all types of tourist destinations,with strong operability and the effectiveness evaluation of which was easier to be quantized.On this basis,low-carbon development thought of nature reserve was proposed by taking Guangxi Longhu Mountain Nature Reserve as the example.Through introduction of general situation of low-carbon tourist resources in Longhu Mountain,it analyzed necessity to design low-carbon tourist products in Longhu Mountain Nature Reserve,designed low-carbon tourist activities according to resources characteristics,and proposed five distinctive low-carbon tour routes in light with different tourists markets.Finally,some relevant suggestions on development had been put forward.
文摘In view of lake scenic areas with abundant tourist resources but less-developed economy,contradictions between the urgency of its tourist resource development and complexity of urban-rural planning compilation were analyzed,and also limitations summarized as insufficient time and fund.Statutory planning contents included in the integrated compilation system were elaborated,and compilation of the integrated planning for the Longhe Lake Scenic Area in the Taihang Mountains was taken for example to introduce planning concepts of the compilation technical system.Considering characteristics of the study area,"regionality" was stressed as the foundation of planning compilation,concise,convenient and practical planning compilation contents were advocated and further explained from the perspectives of compiling by layer and category.In view of this,it is necessary to apply integrated compilation mode under certain circumstances,so as to provide a new approach for the planning compilation of other regions in China and enhance economic and social development of local areas.
文摘Declaration of competing interest statement was not included in the published version.The appropriate declaration of competing interest statement,provided by the authors,is included below.Declaration of competing interest:The authors declare the following financial interests/personal relationships which may be considered as potential competing interests:Jiahua Jin,Liqin Ding,and Biye Wang are employed by the Shanghai Zhonghua Pharmaceutical Co.,Ltd.
基金the research grants from the Joint Project of Shanghai Zhonghua Pharmaceutical Co.,Ltd.and Guangdong Pharmaceutical University(HTDJ2016044)National Natural Science Foundation of China(81870420)+1 种基金the Key Project of Natural Science Foundation of Guangdong Province(2016A030311014),Chinaand the Science and Technology Planning Project of Guangdong Province(2017A020211007),China.
文摘Background and aim:Liver fibrosis resulting from persistent liver injury represents a major healthcare problem globally.Traditional Chinese medicine has played an essential role in the treatment of liver fibrosis in recent years.Thus,this study aims to assess the effect of Longhu Rendan(LHRD),a Chinese traditional patent medicine,on liver fibrosis and its potential mechanism.Methods:The liver fibrosis in mice was induced via the intraperitoneal injection of carbon tetrachloride(CCl4)for 6 weeks or bile duct ligation for 15 days.Various methods were used to judge the therapeutic effect of LHRD.Results:LHRD significantly suppressed the activity of serum index of abnormal liver function,liver cell apoptosis,and necrosis,attenuating liver injury.Moreover,LHRD treatment alleviated liver fibrotic features,such as the reduction of collagen deposition and hepatic stellate cell activation as well as profibrotic gene expression.Mechanistically,LHRD treatment inhibited nuclear transcription factorkappa B signaling and inflammatory gene expression and diminished the production of reactive oxygen species and 4-hydroxynonenal,along with the downregulation of NADPH oxidase 4.Conclusions:Overall,the present study demonstrates that LHRD ameliorates liver injury and fibrosis via the inhibition of inflammation and oxidative stress in mice,indicating that LHRD is a potential medicine for the treatment of liver fibrosis.