This paper exhibits the construction and development of Acupuncture and Moxibustion Hospital of China Academy of Chinese Medical Sciences(CACMS),based on Lian ZHU’s acupuncture academic thought,focusing on the practi...This paper exhibits the construction and development of Acupuncture and Moxibustion Hospital of China Academy of Chinese Medical Sciences(CACMS),based on Lian ZHU’s acupuncture academic thought,focusing on the practice of the hospital development during the past 74 years,from 1951 to 2025,and by analyzing the development trajectory and elaborating the four-dimensional collaborative development mode guided by Lian ZHU’s thought,grounded in clinical evidence,driven by scientific innovation,guided by international standards,and rooted in educational inheritance.(1)After more than 70 years of development,Acupuncture and Moxibustion Hospital of CACMS has developed into the typical small-scaled general hospital of traditional Chinese medicine(TCM)with acupuncture-moxibustion as the main intervention,and has obtained a fruitful achievement in academic research.(2)The Hospital has led and participated in the formulation of a number of clinical practice guidelines of China Association of Acupuncture and Moxibustion,is entitled as the World Health Organization Collaborating Centre for traditional medicine,and has been ranked among the top in the outpatient visits of acupuncture-moxibustion department of TCM hospitals in Beijing for years.(3)There is a well-known professional team of acupuncture-moxibustion of TCM in the Hospital,and with the characteristic modes of acupuncture-moxibustion diagnosis and treatment delivered,the remarkable curative effects have been obtained in treatment of diseases in neurological,gynecological diseases,orthopedic departments,as well as pain disorders,allergic diseases.(4)In the future,facing the opportunities and challenges in the development of global healthcare,it is necessary to deepen the research on“intelligent acupuncture and moxibustion”,integrating modern technologies such as artificial intelligence and big data,exploring the potential value of acupuncture and moxibustion,discovering and innovating theoretical research on acupuncture and moxibustion,establishing scientific methods,standardizing clinical operation techniques,and driving the creative transformation of TCM.(5)The hospital lays the great consideration to the cultivation of acupuncture-moxibustion talents by means of multiple approaches,in order to deeply grasp the essence of TCM and improve the comprehensive quality of talents.(6)The hospital keeps on the leading role of international communication,advancing the international exchange and cooperation of acupuncture and moxibustion,and contributes more eastern wisdom to global health governance,and promote acupuncture and moxibustion of TCM,the treasure of the Chinese nation to display its importance in the world.展开更多
This study summarizes the clinical experience of professor LIAN Jianwei, a nationally renowned traditional Chinese medicine (TCM) practitioner, in treating chronic atrophic gastritis (CAG) with syndrome differentiatio...This study summarizes the clinical experience of professor LIAN Jianwei, a nationally renowned traditional Chinese medicine (TCM) practitioner, in treating chronic atrophic gastritis (CAG) with syndrome differentiation based on pulse-taking. Professor LIAN emphasizes the importance of pulse diagnosis in TCM clinical practice, focusing on the normal and variant aspects of pulse methods, and centers on the dynamic changes of the “Guan pulse” to accurately determine the functional status of the spleen and stomach based on pulse variations, thereby formulating personalized treatment plans. For patients with a slow and moderate pulse, spleen and stomach deficiency and dampness due to spleen deficiency are often identified, and treatment mainly focuses on strengthening the spleen, resolving dampness, and boosting Qi to aid transportation, usually with modifications of Shenling Baizhu San. When the left Guan pulse is string-like and the right Guan pulse is slow and moderate, it indicates liver depression and spleen deficiency, and Xiaoyao San is commonly used to soothe the liver, nourish the blood, and strengthen the spleen, harmonizing the liver and spleen. If the right Guan pulse is large and the left Guan pulse is string-like, it mostly belongs to liver and stomach Qi stagnation, and Bupleurum Liver-soothing powder is often used to soothe the liver, regulate Qi, and harmonize the stomach. A large and empty right Guan pulse suggests insufficiency of Central Qi, and Buzhong Yiqi Tang is commonly used to tonify Qi and soothe the liver. In terms of medication, professor LIAN pays attention to patients’ dietary habits and combines methods of eliminating dampness, promoting digestion, and activating blood circulation to improve symptoms and reverse atrophy.展开更多
Objective: To observe the therapeutic effect of different dosages of Gegen Qin Lian Decoction (葛根芩连汤) on type 2 diabetic patients. Methods: Fifty-four type 2 diabetic patients from low dosage group (20 cases), me...Objective: To observe the therapeutic effect of different dosages of Gegen Qin Lian Decoction (葛根芩连汤) on type 2 diabetic patients. Methods: Fifty-four type 2 diabetic patients from low dosage group (20 cases), medium dosage group (19 cases) and high dosage group (15 cases) were treated with different dosage of Gegen Qin Lian Decoction for 12 weeks. Fasting blood-glucose (FBG), postprandial blood sugar (PBG) and Hemoglobin A1c (HbAlc) were determined before and after treatment. Results: With the increase of dosage, the overall effective rate of glycaemic control increased, and FBG, PBG, HbAlc decreased. The overall effective rate of blood glucose control of high dosage, medium dosage and low dosage group were 80%, 47%, 30% respectively, and there were significant differences between high dosage group and low dosage group. The decrease of FBG, PBG and HbAlc of high dosage showed significant differences from low dosage too. These data was analyzed by trend χ2 test and covariance analysis. Conclusion: The result indicated that different dosage of Gegen Qin Lian Decoction has dose-effect relationship in reducing HbAlc and FBG.展开更多
The genus Hippophae includes deciduous shrubs or small trees,which provide many ecological,economic,and social benefi ts.We assembled and annotated the chloroplast genomes of sympatric Hippophae gyantsensis(Rousi)Lian...The genus Hippophae includes deciduous shrubs or small trees,which provide many ecological,economic,and social benefi ts.We assembled and annotated the chloroplast genomes of sympatric Hippophae gyantsensis(Rousi)Lian and Hippophae rhamnoides Linn subsp.yunnanensis Rousi and comparatively analyzed their sequences.The fulllength chloroplast genomes of H.gyantsensis and H.rhamnoides subsp.yunnanensis were 155,260 and 156,415 bp,respectively;both featured a quadripartite structure with two copies of a large inverted repeat(IR)separated by small(SSC)and large(LSC)single-copy regions.Each Hippophae chloroplast genome contained 131 genes,comprising 85 protein-coding,8 ribosomal RNA,and 38 transfer RNA genes.Of 1302 nucleotide substitutions found between these twogenomes,824(63.29%)occurred in the intergenic region or intron sequences,and 478(36.71%)were located in the coding sequences.The SSC region had the highest mutation rate,followed by the LSC region and IR regions.Among the protein-coding genes,three had a ratio of nonsynonymous to synonymous substitutions(Ka/Ks)>1 yet none were signifi-cant,and 66 had Ka/Ks<1,of which 46 were signifi cant.We found 20 and 16 optimal codons,most of which ended with A or U,for chloroplast protein-coding genes of H.gyantsensis and H.rhamnoides subsp.yunnanensis,respectively.Phylogenetic analysis of fi ve available whole chloroplast genome sequences in the family Elaeagnaceae—using one Ziziphus jujube sequence as the outgroup—revealed that all fi ve plant species formed a monophyletic clade with two subclades:one subclade consisted of three Hippophae species,while the other was formed by two Elaeagnus species,supported by 100%bootstrap values.Together,these results suggest the chloroplast genomes among Hippophae species are conserved,both in structure and gene composition,due to general purifying selection;like many other plants,a signifi cant AT preference was discerned for most proteincoding genes in the Hippophae chloroplast genome.This study provides a valuable reference tool for future research on the general characteristics and evolution of chloroplast genomes in the genus Hippophae.展开更多
The problem of estimating an image corrupted by additive white Gaussian noise has been of interest for practical reasons. Non-linear denoising methods based on wavelets, have become popular but Multiwavelets outperfor...The problem of estimating an image corrupted by additive white Gaussian noise has been of interest for practical reasons. Non-linear denoising methods based on wavelets, have become popular but Multiwavelets outperform wavelets in image denoising. Multiwavelets are wavelets with several scaling and wavelet functions, offer simultaneously Orthogonality, Symmetry, Short support and Vanishing moments, which is not possible with ordinary (scalar) wavelets. These properties make Multiwavelets promising for image processing applications, such as image denoising. The aim of this paper is to apply various non-linear thresholding techniques such as hard, soft, universal, modified universal, fixed and multivariate thresholding in Multiwavelet transform domain such as Discrete Multiwavelet Transform, Symmetric Asymmetric (SA4), Chui Lian (CL), and Bi-Hermite (Bih52S) for different Multiwavelets at different levels, to denoise an image and determine the best one out of it. The performance of denoising algorithms and various thresholding are measured using quantitative performance measures such as, Mean Square Error (MSE), and Root Mean Square Error (RMSE), Signal-to-Noise Ratio (SNR), Peak Signal-to-Noise Ratio (PSNR). It is found that CL Multiwavelet transform in combination with modified universal thresholding has given best results.展开更多
After a review of current studies both home & abroad about face issue, the thesis analyzes the face issues in the movieThe Wedding Banquet from four perspectives with face theory to show the different degrees of c...After a review of current studies both home & abroad about face issue, the thesis analyzes the face issues in the movieThe Wedding Banquet from four perspectives with face theory to show the different degrees of concern, understanding, and views offace between Chinese and American.展开更多
基金Supported by the Basic Scientific Research Business Foundation of the Institute of Acupuncture and Moxibustion,CACMS:ZZ-2023014。
文摘This paper exhibits the construction and development of Acupuncture and Moxibustion Hospital of China Academy of Chinese Medical Sciences(CACMS),based on Lian ZHU’s acupuncture academic thought,focusing on the practice of the hospital development during the past 74 years,from 1951 to 2025,and by analyzing the development trajectory and elaborating the four-dimensional collaborative development mode guided by Lian ZHU’s thought,grounded in clinical evidence,driven by scientific innovation,guided by international standards,and rooted in educational inheritance.(1)After more than 70 years of development,Acupuncture and Moxibustion Hospital of CACMS has developed into the typical small-scaled general hospital of traditional Chinese medicine(TCM)with acupuncture-moxibustion as the main intervention,and has obtained a fruitful achievement in academic research.(2)The Hospital has led and participated in the formulation of a number of clinical practice guidelines of China Association of Acupuncture and Moxibustion,is entitled as the World Health Organization Collaborating Centre for traditional medicine,and has been ranked among the top in the outpatient visits of acupuncture-moxibustion department of TCM hospitals in Beijing for years.(3)There is a well-known professional team of acupuncture-moxibustion of TCM in the Hospital,and with the characteristic modes of acupuncture-moxibustion diagnosis and treatment delivered,the remarkable curative effects have been obtained in treatment of diseases in neurological,gynecological diseases,orthopedic departments,as well as pain disorders,allergic diseases.(4)In the future,facing the opportunities and challenges in the development of global healthcare,it is necessary to deepen the research on“intelligent acupuncture and moxibustion”,integrating modern technologies such as artificial intelligence and big data,exploring the potential value of acupuncture and moxibustion,discovering and innovating theoretical research on acupuncture and moxibustion,establishing scientific methods,standardizing clinical operation techniques,and driving the creative transformation of TCM.(5)The hospital lays the great consideration to the cultivation of acupuncture-moxibustion talents by means of multiple approaches,in order to deeply grasp the essence of TCM and improve the comprehensive quality of talents.(6)The hospital keeps on the leading role of international communication,advancing the international exchange and cooperation of acupuncture and moxibustion,and contributes more eastern wisdom to global health governance,and promote acupuncture and moxibustion of TCM,the treasure of the Chinese nation to display its importance in the world.
基金supported by the Zhejiang Science and Technology Program of TCM(No.2025ZF017)the Clinical Young-Talent Trainning Project in TCM under the Young Eagle Program of the China Association of Chinese Medicine(No.CYJH2024048).
文摘This study summarizes the clinical experience of professor LIAN Jianwei, a nationally renowned traditional Chinese medicine (TCM) practitioner, in treating chronic atrophic gastritis (CAG) with syndrome differentiation based on pulse-taking. Professor LIAN emphasizes the importance of pulse diagnosis in TCM clinical practice, focusing on the normal and variant aspects of pulse methods, and centers on the dynamic changes of the “Guan pulse” to accurately determine the functional status of the spleen and stomach based on pulse variations, thereby formulating personalized treatment plans. For patients with a slow and moderate pulse, spleen and stomach deficiency and dampness due to spleen deficiency are often identified, and treatment mainly focuses on strengthening the spleen, resolving dampness, and boosting Qi to aid transportation, usually with modifications of Shenling Baizhu San. When the left Guan pulse is string-like and the right Guan pulse is slow and moderate, it indicates liver depression and spleen deficiency, and Xiaoyao San is commonly used to soothe the liver, nourish the blood, and strengthen the spleen, harmonizing the liver and spleen. If the right Guan pulse is large and the left Guan pulse is string-like, it mostly belongs to liver and stomach Qi stagnation, and Bupleurum Liver-soothing powder is often used to soothe the liver, regulate Qi, and harmonize the stomach. A large and empty right Guan pulse suggests insufficiency of Central Qi, and Buzhong Yiqi Tang is commonly used to tonify Qi and soothe the liver. In terms of medication, professor LIAN pays attention to patients’ dietary habits and combines methods of eliminating dampness, promoting digestion, and activating blood circulation to improve symptoms and reverse atrophy.
基金supported by a grant from the National Basic Research Program (973 Program, No.2010CB530601)
文摘Objective: To observe the therapeutic effect of different dosages of Gegen Qin Lian Decoction (葛根芩连汤) on type 2 diabetic patients. Methods: Fifty-four type 2 diabetic patients from low dosage group (20 cases), medium dosage group (19 cases) and high dosage group (15 cases) were treated with different dosage of Gegen Qin Lian Decoction for 12 weeks. Fasting blood-glucose (FBG), postprandial blood sugar (PBG) and Hemoglobin A1c (HbAlc) were determined before and after treatment. Results: With the increase of dosage, the overall effective rate of glycaemic control increased, and FBG, PBG, HbAlc decreased. The overall effective rate of blood glucose control of high dosage, medium dosage and low dosage group were 80%, 47%, 30% respectively, and there were significant differences between high dosage group and low dosage group. The decrease of FBG, PBG and HbAlc of high dosage showed significant differences from low dosage too. These data was analyzed by trend χ2 test and covariance analysis. Conclusion: The result indicated that different dosage of Gegen Qin Lian Decoction has dose-effect relationship in reducing HbAlc and FBG.
基金the National Natural Science Foundation of China(31670666)the Fundamental Research Funds for the Central Non-profit Research Institution of Chinese Academy of Forestry(ZDRIF201706).
文摘The genus Hippophae includes deciduous shrubs or small trees,which provide many ecological,economic,and social benefi ts.We assembled and annotated the chloroplast genomes of sympatric Hippophae gyantsensis(Rousi)Lian and Hippophae rhamnoides Linn subsp.yunnanensis Rousi and comparatively analyzed their sequences.The fulllength chloroplast genomes of H.gyantsensis and H.rhamnoides subsp.yunnanensis were 155,260 and 156,415 bp,respectively;both featured a quadripartite structure with two copies of a large inverted repeat(IR)separated by small(SSC)and large(LSC)single-copy regions.Each Hippophae chloroplast genome contained 131 genes,comprising 85 protein-coding,8 ribosomal RNA,and 38 transfer RNA genes.Of 1302 nucleotide substitutions found between these twogenomes,824(63.29%)occurred in the intergenic region or intron sequences,and 478(36.71%)were located in the coding sequences.The SSC region had the highest mutation rate,followed by the LSC region and IR regions.Among the protein-coding genes,three had a ratio of nonsynonymous to synonymous substitutions(Ka/Ks)>1 yet none were signifi-cant,and 66 had Ka/Ks<1,of which 46 were signifi cant.We found 20 and 16 optimal codons,most of which ended with A or U,for chloroplast protein-coding genes of H.gyantsensis and H.rhamnoides subsp.yunnanensis,respectively.Phylogenetic analysis of fi ve available whole chloroplast genome sequences in the family Elaeagnaceae—using one Ziziphus jujube sequence as the outgroup—revealed that all fi ve plant species formed a monophyletic clade with two subclades:one subclade consisted of three Hippophae species,while the other was formed by two Elaeagnus species,supported by 100%bootstrap values.Together,these results suggest the chloroplast genomes among Hippophae species are conserved,both in structure and gene composition,due to general purifying selection;like many other plants,a signifi cant AT preference was discerned for most proteincoding genes in the Hippophae chloroplast genome.This study provides a valuable reference tool for future research on the general characteristics and evolution of chloroplast genomes in the genus Hippophae.
文摘The problem of estimating an image corrupted by additive white Gaussian noise has been of interest for practical reasons. Non-linear denoising methods based on wavelets, have become popular but Multiwavelets outperform wavelets in image denoising. Multiwavelets are wavelets with several scaling and wavelet functions, offer simultaneously Orthogonality, Symmetry, Short support and Vanishing moments, which is not possible with ordinary (scalar) wavelets. These properties make Multiwavelets promising for image processing applications, such as image denoising. The aim of this paper is to apply various non-linear thresholding techniques such as hard, soft, universal, modified universal, fixed and multivariate thresholding in Multiwavelet transform domain such as Discrete Multiwavelet Transform, Symmetric Asymmetric (SA4), Chui Lian (CL), and Bi-Hermite (Bih52S) for different Multiwavelets at different levels, to denoise an image and determine the best one out of it. The performance of denoising algorithms and various thresholding are measured using quantitative performance measures such as, Mean Square Error (MSE), and Root Mean Square Error (RMSE), Signal-to-Noise Ratio (SNR), Peak Signal-to-Noise Ratio (PSNR). It is found that CL Multiwavelet transform in combination with modified universal thresholding has given best results.
文摘After a review of current studies both home & abroad about face issue, the thesis analyzes the face issues in the movieThe Wedding Banquet from four perspectives with face theory to show the different degrees of concern, understanding, and views offace between Chinese and American.
