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Development of Aircraft Maintenance Glossaries in Higher Education:Exploring Methodological Paths to Corpus-Driven Analysis of Key Keywords
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作者 Malila PRADO Daniela TERENZI Diego BRITO 《中国科技术语》 2025年第1期83-93,共11页
This paper presents a project aimed at developing a trilingual visual dictionary for aircraft maintenance professionals and students.The project addresses the growing demand for accurate communication and technical te... This paper presents a project aimed at developing a trilingual visual dictionary for aircraft maintenance professionals and students.The project addresses the growing demand for accurate communication and technical terminology in the aviation industry,particularly in Brazil and China.The study employs a corpus-driven approach,analyzing a large corpus of aircraft maintenance manuals to extract key technical terms and their collocates.Using specialized subcorpora and a comparative analysis,this paper demonstrates challenges and solutions into the identification of high-frequency keywords and explores their contextual use in aviation documentation,emphasizing the need for clear and accurate technical communication.By incorporating these findings into a trilingual visual dictionary,the project aims to enhance the understanding and usage of aviation terminology. 展开更多
关键词 aircraft maintenance CORPUS keyword extraction
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Shortage of storage carbohydrates mainly determines seed abscission in Torreya grandis 'Merrillii'
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作者 Tao Liu Xiaolong Zhao +6 位作者 Guangxia Zhu Caoliang Jin Jingwei Yan Jinwei Suo Weiwu Yu Yuanyuan Hu Jiasheng Wu 《Horticultural Plant Journal》 2025年第2期619-632,共14页
Torreya grandis'Merrillii'is a well-known nut in South China with high nutritional value.Severe premature seed abscission limits the industrial development of T.grandis by causing serious economic losses.Howev... Torreya grandis'Merrillii'is a well-known nut in South China with high nutritional value.Severe premature seed abscission limits the industrial development of T.grandis by causing serious economic losses.However,the physiological mechanisms of seed abscission in T.grandis remain poorly understood.To gain insight into the relationships between carbohydrate status and seed abscission,three-year-old seed-bearing branches were taken as representative materials for the entire tree.Furthermore,the time course of changes in the photosynthetic rate and the non-structural carbohydrate(NSC)dynamics were monitored in the main sources(the one-year-old and two-year-old shoots),and the dry weight and NSC levels of sinks(the seeds,current female cone cluster,and current vegetative cluster)across all seed development stages were recorded.The cumulative seed abscission rate significantly increased,reaching 91.5%from 0 to 72 days after seed protrusion time(SPT).NSC levels in the main sources significantly decreased by 56%-79%,accompanied by a significantly increased photosynthesis rate of 17.1%-49.1%during that period and increased NSC levels in the three sinks.The gene expression level of cell wall invertase(TgCWIN)was significantly correlated with sucrose,fructose,and glucose levels.The carbon storage capacity of the main sources significantly decreased from 6.03 to3.14 mmol C·d^(-1),with a stable photosynthetic capacity,from 0 to 72 days after SPT,whereas the carbon demand of the three sinks showed a continuously increasing trend from 3.14 to 7.71 mmol C·d^(-1).In addition,sucrose supplementation significantly decreased the cumulative seed abscission rate.These results suggest that storage carbohydrates play a major role in the regulatory mechanism of seed abscission in T.grandis.Our study provides a theoretical basis for improving T.grandis yield through establishing a better carbon balance between sources and sinks using timely fertilization or proper pruning procedures. 展开更多
关键词 Storage carbohydrates Seasonal photosynthetic rate Non-structural carbohydrates Seed abscission
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The Significance of the Expression Level of Carbohydrate Antigen 125 (CA125) in Threatened Miscarriage
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作者 Linying Shi Feng Chen +1 位作者 Qin Wang Lingjie Shi 《Journal of Clinical and Nursing Research》 2025年第6期39-45,共7页
Objective:To investigate the expression level of carbohydrate antigen 125(CA125)in threatened miscarriage and explore its significance in the auxiliary diagnosis of threatened miscarriage.Method:Pregnant women who und... Objective:To investigate the expression level of carbohydrate antigen 125(CA125)in threatened miscarriage and explore its significance in the auxiliary diagnosis of threatened miscarriage.Method:Pregnant women who underwent prenatal examinations in the hospital from June 2023 to June 2024 were collected.Among them,66 cases were clinically diagnosed with threatened miscarriage and 74 cases had early normal pregnancies.The expression levels of CA125 in the serum of the above research subjects and the HCG levels of pregnant women with different pregnancy conditions were compared.Result:The expression level of CA125 in the threatened abortion group(119.0±23.37)was significantly higher than that in the normal pregnancy group(57.15±5.554),and the difference was significant(p<0.05).Clinical data analysis showed that the expression level of human chorionic gonadotropin(HCG)in the threatened abortion group(11690±2337)was significantly lower than that in the normal pregnancy group(36130±6855),and there was a significant difference between the two(p<0.05);The expression level of progesterone(P)in the threatened abortion group was also significantly lower than that in the normal pregnancy group(P<0.05).Conclusion:CA125 is abnormally expressed in the serum of pregnant women with threatened miscarriage and can be used as a molecular marker for the auxiliary diagnosis of threatened miscarriage.Regular detection of the concentration of CA125 in the serum of pregnant women can provide a reference for clinical assessment of decidual damage and can be used as an auxiliary basis for predicting the risk of threatened miscarriage. 展开更多
关键词 Threatened miscarriage carbohydrate antigen 125 Molecular markers
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Novel tumor marker index combining carcinoembryonic antigen and carbohydrate antigen 19-9:New prognostic factor for metastatic colorectal cancer
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作者 Yusuf Ilhan Onur Yazdan Balcik +11 位作者 Halil Goksel Guzel Arif Hakan Onder Bilgin Demir Mehmet Nuri Baser Ibrahim Karadag Mehmet Fatih Ozbay Tugrul Burak Genc Sahnura Uzuntas Oguz Poyrazoglu Ismail Beypinar Yakup Ergun Banu Ozturk 《World Journal of Gastrointestinal Oncology》 2025年第5期192-206,共15页
BACKGROUND Metastatic colorectal cancer(mCRC)is a global health challenge with a poor prognosis.Prognostic markers are critical for survival prediction.METHODS This multicenter,retrospective study measured baseline ca... BACKGROUND Metastatic colorectal cancer(mCRC)is a global health challenge with a poor prognosis.Prognostic markers are critical for survival prediction.METHODS This multicenter,retrospective study measured baseline carcinoembryonic antigen and carbohydrate antigen 19-9 levels to calculate a TMI as the geometric mean of values normalized to their upper limits of normal.Receiver operating characteristic curve analysis assessed TMI’s prognostic accuracy,and patients were stratified into high-TMI(≥1.39)and low-TMI(<1.39)groups.The primary endpoint was overall survival(OS),with progression-free survival and treatment response as secondary endpoints.RESULTS The study included 305 mCRC patients with a median follow-up of 22.9 months.The median OS for high-TMI patients was 29.5 months,significantly lower than the 45.6 months observed in the low-TMI group(P=0.02).The 2-year OS rates for the high-and low-TMI groups were 59.4%and 72.9%,respectively.Median progression-free survival was also shorter for the high-TMI group(14.0 vs 16.0 months,P=0.84).High TMI is an independent prognostic factor for worse OS.CONCLUSION TMI is a simple,cost-effective prognostic tool for mCRC,with high TMI associated with poorer survival outcomes. 展开更多
关键词 Colorectal cancer biomarkers Metastatic colorectal cancer Carcinoembryonic antigen carbohydrate antigen 19-9 Tumor marker index
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Commentary on the dose-response effect of pre-exercise carbohydrates in McArdle disease:Methodological considerations and practical implications
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作者 Jiawei Du Jinghua Hou 《Journal of Sport and Health Science》 2025年第2期77-78,共2页
We read with great interest the recent article by Valenzuela et al.1titled“Dose-response effect of pre-exercise carbohydrates under muscle glycogen unavailability:Insights from McArdle disease”published in the Journ... We read with great interest the recent article by Valenzuela et al.1titled“Dose-response effect of pre-exercise carbohydrates under muscle glycogen unavailability:Insights from McArdle disease”published in the Journal of Sport and Health Science The study's exploration of the effects of varying carbohydrate(CHO)doses on exercise capacity in Mc Ardle disease,a condition characterized by complete muscle glycogen unavailability,is a significant contribution to the field of sports science and metabolic disorders. 展开更多
关键词 dose response exercise capacity mcardle disease published muscle glycogen sports science metabolic disorders McArdle disease pre exercise carbohydrates
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柱后衍生液相色谱法测定茶酒中的果糖、葡萄糖和蔗糖
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作者 李丽霞 成洲 +2 位作者 李丹 钟晓雪 罗学平 《中国酿造》 北大核心 2026年第1期288-294,共7页
该研究建立了一种柱后衍生液相色谱法测定茶酒中果糖、葡萄糖和蔗糖含量的方法。采用Asahipak NH2P-50 4E色谱柱(250 mm×4.6 mm,5μm),以含0.5%H3PO4的乙腈-水(75∶25,V/V)为流动相进行等度洗脱,流速0.8 m L/min,柱温40℃,柱后120... 该研究建立了一种柱后衍生液相色谱法测定茶酒中果糖、葡萄糖和蔗糖含量的方法。采用Asahipak NH2P-50 4E色谱柱(250 mm×4.6 mm,5μm),以含0.5%H3PO4的乙腈-水(75∶25,V/V)为流动相进行等度洗脱,流速0.8 m L/min,柱温40℃,柱后120℃下采用2.0 g/L高碘酸氧化、1.0 g/L酚试剂进行衍生显色,于波长670 nm处检测。结果表明,果糖在25.0~500.0 mg/L、葡萄糖和蔗糖在50.0~1 000.0 mg/L质量浓度范围内具有良好的线性关系,相关系数(R^(2))>0.999,方法 检出限为2.58~9.64 mg/L,定量限为7.82~29.21 mg/L,加标回收率为96.55%~98.73%,精密度、稳定性试验结果相对标准偏差均<2.00%。利用本方法对市售的4类共11款茶酒中3种糖含量进行检测,结果表明在所有茶酒中均检测出葡萄糖,含量为0.038~111.36 g/L,10款茶酒中检测出果糖,含量为0.023~115.90 g/L,其中配制型茶酒中的葡萄糖、果糖含量最高;蔗糖仅在3款露酒型茶酒中检出,含量为0.012~0.380 g/L。该方法操作简便、试剂成本低、回收率高,可为茶酒的工艺研究、产品开发及标准制定等提供新的检测技术支持。 展开更多
关键词 液相色谱 柱后衍生 紫外检测 茶酒 糖类物质
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Study on the Changes of Non-structural Carbohydrates and Nitrogen Contents of Quercus aquifolioides Scrub along Different Elevation Gradient 被引量:2
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作者 黄亚洲 吴杰 +3 位作者 孟玉山 吕俊 王三根 朱万泽 《Agricultural Science & Technology》 CAS 2011年第4期576-580,共5页
[Objective] The aim was to compare the content changes between the non-structural carbohydrates(NSC)and the total nitrogen in various growing seasons,and to explore the response relationship between altitude and the... [Objective] The aim was to compare the content changes between the non-structural carbohydrates(NSC)and the total nitrogen in various growing seasons,and to explore the response relationship between altitude and the contents.[Method] Taking Quercus aquifolioides scrub which widely distributed in Zheduoshan in the west of Sichuan as the experimental objects,the changes between NSC and the toal nitrogen in various growing seasons at different altitude were studied.[Result] The results showed that the content of NSC in Quercus aquifolioides underground increased with the lift of elevation in the dormancy,but decreased in the early germination,growing period and growth stage.The content of NSC in the ground tissue changed non-linearly with increasing elevation.In addition,the total nitrogen of Quercus aquifolioides organizations was decreasing with increasing elevation in the dormant period,which did not change significantly in the other periods.This result implied that the content of NSC in Quercus aquifolioides underground was more sensitive to temperature.[Conclusion] The experiment laid basis for the exploration of the physical and ecological mechanism of underground plants adaptability to highland environment,their response to global climate changes and adjustment to high altitude ecological system. 展开更多
关键词 Quercus aquifolioides Total nitrogen NON-STRUCTURAL carbohydrates ELEVATION
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Effects of salinity fluctuation and dietary protein/ carbohydrate ratio on the survival and growth of Juvenile Litopenaeus vannamei 被引量:1
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作者 王兴强 曹梅 阎斌伦 《Marine Science Bulletin》 CAS 2010年第2期61-73,共13页
A factorial study was conducted to determine the effects of salinity (constant (SO) and fluctuating (S10)) and isoenergetic diet of different protein/carbohydrate ratios (P/C: 4.1, 1.9, 1.0 and 0.6) on the su... A factorial study was conducted to determine the effects of salinity (constant (SO) and fluctuating (S10)) and isoenergetic diet of different protein/carbohydrate ratios (P/C: 4.1, 1.9, 1.0 and 0.6) on the survival and growth of juvenile Litopenaeus vannamei. The experiment lasted for 35 days. The results showed that I) At S0 and S10, specific growth rate and apparent digestibility coefficient exhibited decreasing trend, while food conversion ratio exhibited increasing trend, with decreasing P/C ratio. At SO, food consumption and specific growth rate of the shrimp fed 4.1 P/C were significantly higher than those fed 1.0 and 0.6 P/C, whereas at S10, no significant differences were detected among different treatments; II) At 4.1 and 1.9 P/C, food consumption and specific growth rate were higher in the shrimp maintained at SO as compared with those at S10, while at 1.0 and 0.6 P/C, an inverse trend was observed. Among four P/C ratios, food conversion ratio of the shrimp at SO was the lowest. 展开更多
关键词 Litopenaeus vannamei salinity fluctuation protein/carbohydrate ratio SURVIVAL growth
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Effect of Carbohydrate Content in Feed on the Daily Metabolic Rate of S. meridionalis 被引量:1
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作者 付世建 谢小军 《Agricultural Science & Technology》 CAS 2007年第3期68-72,共5页
The routine metabolic rate in southern catfish juvenile(24.3-250.8 g)fed with saccharine feed(CHO)was measured in this study.Fish were fed with iso-nitrogenous(40 % crude protein)and iso-lipidic(10% crude lipid)experi... The routine metabolic rate in southern catfish juvenile(24.3-250.8 g)fed with saccharine feed(CHO)was measured in this study.Fish were fed with iso-nitrogenous(40 % crude protein)and iso-lipidic(10% crude lipid)experimental feed containing 0(control feed),15%,30% of carbohydrate level.The routine metabolic rates of 15 % and 30% dietary carbohydrate group were significantly higher than that of 0% dietary carbohydrate group.The relationship between body mass(Wt)and routine metabolic rate(Rr)of southern catfishfed with different test feed could be described as:(1)0% CHO:ln(Rr)=0.986 ln(Wt)+1.419 r2=0.922,n=25,P<0.001;(2)15% CHO:ln(Rr)=0.912 ln(Wt)+1.741 r2=0.966,n=21,P<0.001;(3)30% CHO:ln(Rr)=0.762 ln(Wt)+2.378 r2=0.958,n=21,P<0.001.The intercept was increased and mass coefficient was decreased with the increase of carbohydrate level in feed.It could be concluded that southern Silurus meridionalis had poor metabolic capacity which led the increase of routine metabolic rate of fish with small size.But with the increase of body size southern Silurus meridionalis might had a better adaptation to high carbohydrate concentration. 展开更多
关键词 Routine metabolic rate carbohydrate Silurus meridionalis
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枸杞多糖对狭小空间应激引发肠道炎症的干预作用
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作者 李国强 王倩楠 +5 位作者 乔亚俊 戎林 张行方 贺奇峰 魏立新 毕宏涛 《天然产物研究与开发》 北大核心 2026年第1期149-157,68,共10页
初步探讨枸杞水溶性多糖(Lycii Fructus water-soluble polysaccharide,LFWP)的组成含量及其主链单糖组成特征,并进一步评估其对狭小空间环境应激引发小鼠肠道炎症的干预作用。采用部分酸水解、1-苯基-3甲基-5-吡唑酮(1-phenyl-3-methyl... 初步探讨枸杞水溶性多糖(Lycii Fructus water-soluble polysaccharide,LFWP)的组成含量及其主链单糖组成特征,并进一步评估其对狭小空间环境应激引发小鼠肠道炎症的干预作用。采用部分酸水解、1-苯基-3甲基-5-吡唑酮(1-phenyl-3-methyl-5-pyrazolone,PMP)柱前衍生化、高效凝胶渗透色谱法、傅里叶红外光谱和扫描电子显微镜等方法分析LFWP的组成和结构特征;HE染色和ELISA法评价LFWP对狭小空间应激引发小鼠肠道炎症的干预效果。组成结构研究表明,LFWP糖含量为90.5 mg/g,糖醛酸含量为10.7 mg/g,蛋白含量为0.4 mg/g,存在一个分布均一的主链部分,以半乳糖为主要单糖。药理活性研究表明,狭小空间环境造成小鼠结肠组织受损和炎性细胞浸润;表现为小鼠血清中肿瘤坏死因子-α(tumor necrosis factor-α,TNF-α)、白细胞介素-1β(interleukin-1β,IL-1β)、IL-6含量增加(P<0.001),IL-10含量降低(P<0.001);结肠组织中脂多糖(lipopolysaccharide,LPS)、TNF-α、IL-1β、IL-6含量增加(P<0.001,P<0.05,P<0.01),钙卫蛋白(calprotectin,CALP)水平和髓过氧化物酶(myeloperoxidase,MPO)活性增加(P<0.05,P<0,01),IL-10含量降低(P<0.001),说明长期狭小空间环境应激引发小鼠肠道炎症。LFWP高剂量组干预明显降低小鼠血清TNF-α、IL-1β和IL-6水平(P<0.01,P<0.001),升高IL-10水平(P<0.001);同时明显降低小鼠结肠组织中LPS、TNF-α、IL-1β和IL-6水平(P<0.001),升高IL-10(P<0.05)水平,使结肠中CALP(P<0.001)水平和MPO(P<0.01)活性趋于正常。LFPW干预可显著改善狭小空间环境对小鼠肠道的应激损伤。 展开更多
关键词 枸杞水溶性多糖 单糖组成 狭小空间 肠道炎症
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施肥对轻木生长和非结构性碳水化合物的影响
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作者 段贵河 吴俊文 +4 位作者 赵志娟 李志琪 陈刚 文程敬 杜官本 《西北林学院学报》 北大核心 2026年第1期107-118,共12页
通过探究不同施肥情况对轻木生长和非结构性碳水化合物的影响,筛选适合轻木培育的施氮量和肥料类型,为轻木施肥提供合理的建议。以2年生轻木林地为试验地,采用随机区组设计,设置3个梯度的尿素处理(N),分别为N1(尿素300 g/株)、N2(尿素45... 通过探究不同施肥情况对轻木生长和非结构性碳水化合物的影响,筛选适合轻木培育的施氮量和肥料类型,为轻木施肥提供合理的建议。以2年生轻木林地为试验地,采用随机区组设计,设置3个梯度的尿素处理(N),分别为N1(尿素300 g/株)、N2(尿素450 g/株)、N3(尿素600 g/株),3个梯度的缓释氮肥处理(H)分别为H1(缓释氮肥300 g/株)、H2(缓释氮肥450 g/株)、H3(缓释氮肥600 g/株),以不施加氮肥为对照(CK),测量轻木胸径、树高,测定叶、枝和根的非结构性碳水化合物及其组分含量。结果表明:1)施肥量、取样检测时间和肥料类型均显著影响轻木的胸径和树高。在不同的取样检测时间,随着施肥量的增加树高和胸径也随之增加,90 d取样检测时H2的树高和胸径最大,较CK处理分别显著增大14.0%、16.9%。2)施肥量、检测时间均显著影响轻木3个器官的NSC及其组分含量,不同类型肥料均会促进叶NSC及其组分含量的增加,随着施肥量的增加,在不同的取样检测时间,施尿素处理的叶NSC含量较施缓释氮肥的增长幅度小(55.3%<59.3%),相较于尿素,缓释氮肥更有利于叶NSC含量的积累。3)树高、胸径、叶可溶性糖和NSC含量可以更好地反映施肥效果,树高和胸径与叶的非结构性碳含量呈极显著正相关(P<0.01),且施肥会增强生长和非结构性碳之间的关联性,树高、胸径、叶可溶性糖、叶淀粉、枝可溶性糖、枝淀粉、根可溶性糖是轻木对施肥响应的重要指标,H2处理是轻木最佳的施肥处理。施肥显著影响轻木生长和NSC积累,轻木叶NSC含量决定轻木的生长,H2施肥处理最利于轻木的生长,建议对轻木进行养分添加时,采用缓释氮肥450 g/株。 展开更多
关键词 氮肥 轻木 林木生长 非结构性碳水化合物
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艾司氯胺酮对乳腺癌根治术患者认知功能及血清CA125、CEA水平的影响
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作者 刘任丽 王绚 +3 位作者 梁冰 梁晶光 朱建坡 王雪娜 《分子诊断与治疗杂志》 2026年第1期89-91,95,共4页
目的探究艾司氯胺酮对乳腺癌根治术患者认知功能及血清糖类抗原125(CA125)、癌胚抗原(CEA)水平的影响。方法纳入2022年12月至2024年12月于河南中医药大学第一附属医院行乳腺癌根治术的204例乳腺癌患者,随机分为对照组(n=102)和观察组(n=... 目的探究艾司氯胺酮对乳腺癌根治术患者认知功能及血清糖类抗原125(CA125)、癌胚抗原(CEA)水平的影响。方法纳入2022年12月至2024年12月于河南中医药大学第一附属医院行乳腺癌根治术的204例乳腺癌患者,随机分为对照组(n=102)和观察组(n=102),所有患者均进行常规麻醉。手术切皮前,观察组静注艾司氯胺酮,对照组静注生理盐水。比较两组麻醉前、术后48 h认知功能[简易智能精神状态检查量表(MMSE)]和疼痛情况[疼痛视觉模拟评分法(VAS)],对比两组麻醉前及术后7日血清学指标[CA125、CEA、白细胞介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)],对比两组不良反应发生情况。结果麻醉后,两组MMSE评分均降低,VAS评分均升高,且观察组MMSE评分高于对照组,VAS评分低于对照组,差异有统计学意义(P<0.05);麻醉后,两组血清CA125、CEA水平均降低,且观察组低于对照组,差异有统计学意义(P<0.05);麻醉后,两组血清IL-6、TNF-α水平均降低,且观察组低于对照组,差异有统计学意义(P<0.05);两组间不良反应总发生率比较差异无统计学意义(P>0.05)。结论艾司氯胺酮可减轻乳腺癌根治术患者认知功能损伤及术后疼痛,降低术后血清CA125、CEA水平及炎症因子表达水平,且该治疗方案整体安全性良好。 展开更多
关键词 艾司氯胺酮 乳腺癌根治术 认知功能 糖类抗原125 癌胚抗原
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肾脏疾病患者肿瘤标志物水平与醛固酮的相关性研究
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作者 刘平 陈雪雯 部楠 《首都食品与医药》 2026年第1期81-83,共3页
目的分析肾脏疾病患者主要肿瘤标志物、肾素及醛固酮水平变化及相关性,为肾脏疾病临床诊疗提供参考依据。方法选取2024年1月-2024年12月本院收治的68例肾脏疾病患者作为本次研究对象,选取同期68例健康体检者作为对照组,分析患者肿瘤标... 目的分析肾脏疾病患者主要肿瘤标志物、肾素及醛固酮水平变化及相关性,为肾脏疾病临床诊疗提供参考依据。方法选取2024年1月-2024年12月本院收治的68例肾脏疾病患者作为本次研究对象,选取同期68例健康体检者作为对照组,分析患者肿瘤标志物、肾素及醛固酮的水平。结果与对照组比较,肾脏疾病患者CEA、CA19-9、CA211、ALD、DR水平均显著高于对照组,AFP低于对照组,均具有统计学意义。Pearson相关性分析表明CA211与ALD呈正相关,其他肿瘤标志物与ALD无相关性;主要肿瘤标志物与DR均无相关性。结论血清肿瘤标志物在肾脏疾病患者中水平升高,能为疾病的诊疗提供一定的参考依据。CA211与ALD呈正相关可能为肾脏疾病的病理机制提供新视角。 展开更多
关键词 甲胎蛋白 癌胚抗原 糖类抗原19-9 细胞角蛋白十九片段 醛固酮
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WoS题录Keywords字段关键词频度统计程序设计与实现 被引量:1
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作者 朱玉强 《情报探索》 2015年第6期86-89,共4页
使用Visual Basic编程,采用正则表达式批量提取由Web of Science导出的Bib Tex题录中所有Keywords字段关键词,按需合并所得关键词的同义词、近义词及词形变化词,然后将出现频度的统计数据写入Excel表,并编制Excel宏自动生成折线图,实现... 使用Visual Basic编程,采用正则表达式批量提取由Web of Science导出的Bib Tex题录中所有Keywords字段关键词,按需合并所得关键词的同义词、近义词及词形变化词,然后将出现频度的统计数据写入Excel表,并编制Excel宏自动生成折线图,实现关键词分布的简单可视化。情报工作者后续可借助Excel功能对该程序生成的Excel表执行复杂的数据组合分析,以提高工作效率。 展开更多
关键词 Web of Science(WoS) 关键词 词频统计 Excel BibTex Visual Basic(VB)
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阿替利珠单抗与信迪利单抗治疗中晚期非小细胞肺癌的疗效及对患者CYFRA21-1、CA125的影响分析
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作者 刘婷 周凯 《中国现代药物应用》 2026年第1期10-14,共5页
目的探究阿替利珠单抗与信迪利单抗治疗中晚期非小细胞肺癌的疗效及对患者细胞角蛋白19的可溶性片段(CYFRA21-1)、糖类抗原125(CA125)的影响。方法研究对象为我院收治的67例中晚期非小细胞肺癌患者,所选取年限为2021年1月~2023年1月,按... 目的探究阿替利珠单抗与信迪利单抗治疗中晚期非小细胞肺癌的疗效及对患者细胞角蛋白19的可溶性片段(CYFRA21-1)、糖类抗原125(CA125)的影响。方法研究对象为我院收治的67例中晚期非小细胞肺癌患者,所选取年限为2021年1月~2023年1月,按照研究方法不同分为对照组32例(信迪利单抗治疗)和观察组35例(阿替利珠单抗治疗)。对比两组患者细胞生长因子[血管内皮生长因子(VEGF)、碱性成纤维细胞生长因子(bFGF)、基质金属蛋白酶-9(MMP-9)]、肿瘤标志物[CA125、癌胚抗原(CEA)、糖类抗原19-9(CA19-9)]、CYFRA21-1、免疫功能指标(CD4^(+)、CD8^(+)、CD4^(+)/CD8^(+))水平及不良反应发生情况。结果治疗后,两组MMP-9、VEGF、bFGF水平均较本组治疗前降低,且观察组MMP-9(312.22±27.68)mg/ml、VEGF(169.62±19.65)pg/ml、bFGF(14.89±3.19)ng/L较对照组的(335.84±31.90)mg/ml、(185.47±20.82)pg/ml、(17.11±3.24)ng/L更低,有统计学差异(P<0.05)。治疗后,两组CD8^(+)较本组治疗前下降,CD4^(+)/CD8^(+)、CD4^(+)较本组治疗前提高,且观察组CD8^(+)(21.23±2.08)%较对照组的(23.10±2.19)%更低,CD4^(+)/CD8^(+)(1.72±0.49)、CD4^(+)(38.02±4.01)%较对照组的(1.47±0.26)、(35.70±3.86)%更高,有统计学差异(P<0.05)。治疗后,两组CYFRA21-1水平较本组治疗前下降,且观察组较对照组CYFRA21-1水平(5.87±0.89 vs.7.54±1.0)ng/ml更低,有统计学差异(P<0.05)。治疗后,两组CA19-9、CA125、CEA水平较本组治疗前下降,且观察组CA19-9(32.28±5.77)U/ml、CA125(23.21±5.87)U/ml、CEA(8.43±0.60)μg/L较对照组的(35.65±5.32)U/ml、(26.86±6.12)U/ml、(9.13±0.75)μg/L更低,有统计学差异(P<0.05)。观察组较对照组提高肝功能异常发生率,而降低胃肠道反应、骨髓抑制、腹泻发生率,但无统计学差异(P>0.05)。结论中晚期非小细胞肺癌患者使用阿替利珠单抗与信迪利单抗治疗后,细胞因子和肿瘤标志物水平均得到改善,免疫功能升高,CYFRA21-1水平下调,其中阿替利珠单抗的临床效果更显著。 展开更多
关键词 中晚期非小细胞肺癌 阿替利珠单抗 信迪利单抗 细胞角蛋白19的可溶性片段 糖类抗原125
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凡纳滨对虾肝胰腺响应微囊藻毒素-LR胁迫的代谢机制
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作者 邢瑞爱 张达娟 +3 位作者 王其鹏 张志华 宫超然 毕相东 《福建农林大学学报(自然科学版)》 北大核心 2026年第1期77-87,共11页
【目的】高密度集约化养殖中,蓝藻水华暴发会释放出大量微囊藻毒素(MCs),研究MCs对凡纳滨对虾肝胰腺的毒性作用代谢机制,为水产养殖业健康发展提供依据。【方法】采用血窦注射法对凡纳滨对虾进行微囊藻毒素-LR(MC-LR)攻毒试验,在测定对... 【目的】高密度集约化养殖中,蓝藻水华暴发会释放出大量微囊藻毒素(MCs),研究MCs对凡纳滨对虾肝胰腺的毒性作用代谢机制,为水产养殖业健康发展提供依据。【方法】采用血窦注射法对凡纳滨对虾进行微囊藻毒素-LR(MC-LR)攻毒试验,在测定对虾肝胰腺氧化损伤及主要抗氧化酶活性的基础上对攻毒2、72 h的肝胰腺进行非靶向代谢组学分析,寻找差异代谢物及显著代谢通路,从代谢水平上揭示MC-LR对肝胰腺的影响机制。【结果】随着MC-LR胁迫时间的延长,凡纳滨对虾肝胰腺丙二醛(MDA)和脂质过氧化物(LPO)浓度逐渐升高,肝胰腺氧化损伤明显;谷胱甘肽过氧化物酶(GSHPX)、谷胱甘肽还原酶(GR)和谷胱甘肽-S-转移酶(GST)活性均呈先升高后降低的趋势。攻毒2、72 h,肝胰腺的差异代谢物分别为144、175个,主要为L-酪氨酸、L-天冬氨酸、L-缬氨酸和柠檬酸等,共有差异代谢物57个(包括反丁烯二酸、琥珀酸、N6,N6,N6-三甲基-L-赖氨酸等);攻毒2、72 h,KEGG显著富集通路分别有18、26条,主要有碳水化合物代谢(包括柠檬酸循环、丙酮酸代谢等)、核苷酸代谢(包括嘌呤代谢等)和氨基酸代谢(包括半胱氨酸与蛋氨酸代谢、丙酸盐代谢、苯丙氨酸代谢等)通路。【结论】MC-LR胁迫下,凡纳滨对虾肝胰腺发生氧化应激、细胞凋亡、能量代谢过程加快、细胞稳态维持和生长,以对抗MC-LR对机体产生的胁迫和损伤。 展开更多
关键词 凡纳滨对虾 微囊藻毒素 抗氧化酶 非靶向代谢组学 碳水化合物代谢 氨基酸代谢
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Effects of culm carbohydrate partitioning on basal stem strength in a high-yielding rice population 被引量:19
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作者 Jun Zhang Ganghua Li +7 位作者 Qingyu Huang Zhenghui Liu Chengqiang Ding She Tang Lin Chen Shaohua Wang Yanfeng Ding Weijian Zhang 《The Crop Journal》 SCIE CAS CSCD 2017年第6期478-487,共10页
Rice culm carbohydrate transport can simultaneously affect grain filling and stem lodging resistance by regulating non-structural carbohydrate(NSC) and structural carbohydrate(SC) contents. However, the relationship b... Rice culm carbohydrate transport can simultaneously affect grain filling and stem lodging resistance by regulating non-structural carbohydrate(NSC) and structural carbohydrate(SC) contents. However, the relationship between carbohydrate transposition and culm strength is not well documented. Accordingly, a high-yielding hybrid rice cultivar(Y Liangyou 2) was tested under different N fertilization regimes at two locations, Taoyuan(a special high-yield eco-site), Yunnan province and Danyang(a representative eco-site of the middle and lower Yangtze), Jiangsu province, China. Significantly higher grain yield and basal stem strength were found at Taoyuan than Danyang under all N rates throughout the two-year experiment. At heading stage, soluble sugars, starch, cellulose and lignin contents of the basal culm at Taoyuan were significantly 132.0%, 73.7%, 1.2%, and 62.7% higher than those at Danyang, respectively. At 20 days after heading, soluble sugars and starch content at Taoyuan decreased significantly compared to Danyang, but lignin content remained higher. Culm carbohydrate transport to kernels at Taoyuan was significantly greater than that at Danyang, and the proportion of soluble sugars and starch was correspondingly 62.9%lower. However, the proportion of lignin and cellulose was 22.7% higher at Taoyuan than that at Danyang. Soluble sugars and starch partitioning were significantly reduced under an increased nitrogen application rate, but SC partitioning was little affected. There were significant positive correlations between basal culm bending stress and dry weight and cellulose and lignin proportions at both locations under all N rates, suggesting that the higher SC proportion at 20 days after heading was primarily responsible for culm strength.These results suggest that high-yielding rice populations with greater culm strength require both moderate NSC transport and greater SC accumulation. 展开更多
关键词 RICE HIGH-YIELDING LODGING CULM strength carbohydrate partitioning
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Top-dressing nitrogen fertilizer rate contributes to decrease culm physical strength by reducing structural carbohydrate content in japonica rice 被引量:20
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作者 ZHANG Wu-jun WU Long-mei +7 位作者 DING Yan-feng WENG Fei WU Xiao-ran LI Gang-hua LIU Zheng-hui TANG She DING Cheng-qiang WANG Shao-hua 《Journal of Integrative Agriculture》 SCIE CAS CSCD 2016年第5期992-1004,共13页
Lodging is an important factor limiting rice yield and quality by bending or breaking stem in japonica rice(Oryza sativa L.) production. The objectives of this study were to determine the mechanism of lodging resist... Lodging is an important factor limiting rice yield and quality by bending or breaking stem in japonica rice(Oryza sativa L.) production. The objectives of this study were to determine the mechanism of lodging resistance in japonica rice as affected by carbohydrate components, especially its related arrangement in culm tissue and response to top-dressing nitrogen(N) fertilizer. Field experiments were conducted in Danyang County, Jiangsu Province, China, by using two japonica rice varieties Wuyunjing 23(lodging-resistance variety) and W3668(lodging-susceptible variety) with three top-dressing N fertilizer rates(0, 135 and 270 kg N ha^(-1)) in 2013 and 2014. Lodging related physical parameters, morphological characteristics and stem carbohydrate components were investigated at 30 d after full heading stage. Results showed that with increasing N fertilizer rates, the lodging rate and lodging index increased rapidly primarily due to significant reduction of breaking strength in two japonica rice varieties. Correlation analysis revealed that breaking strength was significantly and positively correlated with bending stress, but negatively correlated with section modulus, except for significant correlation at W3668 in 2014. Higher stem plumpness status and structural carbohydrate contents significantly enhanced stem stiffness, despite of lower non-structural carbohydrate. With higher N fertilizer rate, the culm wall thickness was almost identical, and culm diameter increased slightly. The structural carbohydrates, especially for lignin content in culm, reduced significantly under high N rate. Further histochemical staining analysis revealed that high N treatments decreased the lignin deposition rapidly in the sclerenchyma cells of mechanical tissue, large vascular bundle and small vascular bundle region, which were consistent with reduction of bending stress, especially for W3668 and thus, resulted in poor stem strength and higher lodging index. These results suggested that structural carbohydrate plays a vital role for improving stem strength in japonica rice. N rate decreased lodging resistance primarily due to poor stem stiffness, by reducing structural carbohydrate content and lignin deposition in the secondary cell wall of lower internode culm tissue. 展开更多
关键词 japonica rice lodging resistance NITROGEN stem strength structural carbohydrate
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Profile distribution and seasonal dynamics of water-extractable carbohydrate in soils under mixed broad-leaved Korean pine forest on Changbai Mountain 被引量:7
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作者 ZHAO Shan-shan SUN Jin-bing CUI Xiao-yang 《Journal of Forestry Research》 SCIE CAS CSCD 2013年第3期509-514,共6页
Carbohydrate represents an important part of the soil labile organic carbon pool. Water soluble carbohydrate drives the C cycle in forest soil by affecting microbial activity and hot water extractable car- bohydrate i... Carbohydrate represents an important part of the soil labile organic carbon pool. Water soluble carbohydrate drives the C cycle in forest soil by affecting microbial activity and hot water extractable car- bohydrate is thought related to soil carbon sequestration due to the asso- ciation with soil aggregation. In a temperate forest region of northeast China, Changbai Mountain, we investigated the abundance, spatial dis- tribution, and seasonal dynamics of cool and hot-water extractable car- bohydrate in soils under mixed broad-leaved Korean pine forest. The concentrations of cool-water extractable carbohydrate (CWECH) in three soil layers (0-5, 5-10, 10-20 cm) ranged from 4.1 to 193.3 g.kg-1 dry soil, decreasing rapidly with soil depth. On an annual average, the CWECH concentrations in soils at depths of 5-10 and 10-20 cm were 54.2% and 24.0%, respectively, of that in the 0-5 cm soil layer. CWECH showed distinct seasonal dynamics with the highest concentrations in early spring, lowest in summer, and increasing concentrations in autumn. Hot-water extractable carbohydrate (HWECH) concentrations in three soil layers ranged from 121.4 to 2026.2 g.kgq dry soil, which were about one order of magnitude higher than CWECH. The abundance of HWECH was even more profile-dependent than CWECH, and decreased more rapidly with soil depth. On an annual average, the HWECH concentration in soils 10-20 cm deep was about one order of magnitude lower than that in the top 0-5 cm soil. The seasonality of HWECH roughly tracked that of CWECH but with seasonal fluctuations of smaller amplitude. The car- bohydrate concentrations in cool/hot water extracts of soil were positively correlated with UV254 and UV2s0 of the same solution, which has implications for predicting the leaching loss of water soluble organic carbon. 展开更多
关键词 forest soil cool-water extractable carbohydrate hot-waterextractable carbohydrate profile distribution seasonal dynamics
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Response to strict and liberalized specific carbohydrate dietin pediatric Crohn's disease 被引量:10
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作者 Jennifer C Burgis Kaylie Nguyen +1 位作者 KT Park Kenneth Cox 《World Journal of Gastroenterology》 SCIE CAS 2016年第6期2111-2117,共7页
AIM: To investigate the specific carbohydrate diet(SCD) as nutritional therapy for maintenance of remission in pediatric Crohn's disease(CD). METHODS: Retrospective chart review was conducted in 11 pediatric patie... AIM: To investigate the specific carbohydrate diet(SCD) as nutritional therapy for maintenance of remission in pediatric Crohn's disease(CD). METHODS: Retrospective chart review was conducted in 11 pediatric patients with CD who initiated the SCD as therapy at time of diagnosis or flare. Two groups defined as SCD simple(diet alone, antibiotics or 5-ASA) or SCD with immunomodulators(corticosteroids and/or stable thiopurine dosing) were followed for one year and compared on disease characteristics, laboratory values and anthropometrics.RESULTS: The mean age at start of the SCD was 11.8 ± 3.0 years(range 6.6-17.6 years) with five patients starting the SCD within 5 wk of diagnosis. Three patients maintained a strict SCD diet for the study period and the mean time for liberalization was 7.7 ± 4.0 mo(range 1-12) for the remaining patients. In both groups, hematocrit, albumin and ESR values improved while on strict SCD and appeared stable after liberalization(P-value 0.006, 0.002, 0.002 respectively). The majority of children gained in weight and height percentile while on strict SCD, with small loss in weight percentile documented with liberalization. CONCLUSION: Disease control may be attainable with the SCD in pediatric CD. Further studies are needed to assess adherence, impact on mucosal healing and growth. 展开更多
关键词 SPECIFIC carbohydrate diet Crohn's disease PEDIATRICS Nutrition therapy
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