摘要
目的分析肾脏疾病患者主要肿瘤标志物、肾素及醛固酮水平变化及相关性,为肾脏疾病临床诊疗提供参考依据。方法选取2024年1月-2024年12月本院收治的68例肾脏疾病患者作为本次研究对象,选取同期68例健康体检者作为对照组,分析患者肿瘤标志物、肾素及醛固酮的水平。结果与对照组比较,肾脏疾病患者CEA、CA19-9、CA211、ALD、DR水平均显著高于对照组,AFP低于对照组,均具有统计学意义。Pearson相关性分析表明CA211与ALD呈正相关,其他肿瘤标志物与ALD无相关性;主要肿瘤标志物与DR均无相关性。结论血清肿瘤标志物在肾脏疾病患者中水平升高,能为疾病的诊疗提供一定的参考依据。CA211与ALD呈正相关可能为肾脏疾病的病理机制提供新视角。
Objective To analyze the changes and correlations of major tumor markers,renin,and aldosterone levels in patients with kidney diseases,and provide a reference for clinical diagnosis and treatment of kidney diseases.Methods A total of 68 patients with kidney diseases admitted to our hospital from January 2024 to December 2024 were selected as the research subjects,and 68 healthy physical examinees during the same period were selected as the control group to analyze the levels of tumor markers,renin,and aldosterone.Results Compared with the control group,the levels of CEA,CA19-9,CA211,ALD,and DR in kidney disease patients were significantly higher than those in the control group,while AFP was lower than that in the control group,all of which were statistically significant.Pearson correlation analysis showed that CA211 was positively correlated with ALD,while other tumor markers had no correlation with ALD,and major tumor markers had no correlation with DR.Conclusion Serum tumor marker levels are increased in patients with kidney diseases,which can provid a certain reference for disease diagnosis and treatment.The positive correlation between CA211 and ALD may provide a new perspective for the pathological mechanisms of kidney diseases.
作者
刘平
陈雪雯
部楠
Liu Ping;Chen Xuewen;Bu Nan(Tianjin Academy of Traditional Chinese Medicine Affiliated Hospital,Tianjin 300120,China)
出处
《首都食品与医药》
2026年第1期81-83,共3页
Capital Food Medicine
关键词
甲胎蛋白
癌胚抗原
糖类抗原19-9
细胞角蛋白十九片段
醛固酮
Alpha-Fetoprotein(AFP)
Carcinoembryonic Antigen(CEA)
Carbohydrate Antigen 19-9(CA19-9)
Cytokeratin 19 Fragment(CA211)
aldosterone(ALD)
