In this paper,we first prove the openness theorems on convergence of the twisted Kähler-Ricci flows.Then as applications,we improve Perelman's estimates along the twisted Kähler-Ricci flows and give crit...In this paper,we first prove the openness theorems on convergence of the twisted Kähler-Ricci flows.Then as applications,we improve Perelman's estimates along the twisted Kähler-Ricci flows and give criteria for the convergence of twisted Kähler-Ricci flows in relation to the greatest twisted Ricci lower bound,which gives a geometric interpretation of the greatest twisted Ricci lower bound from the viewpoint of geometric flows.展开更多
目的分析副溶血弧菌O10:K4血清型O抗原基因簇的分子特征,并构建基于基因组的分子血清型预测数据库。方法从美国国家生物技术信息中心Assembly数据库获取副溶血弧菌O抗原基因簇序列,使用blastn、fastANI、Sourmash和p i x y工具分析序列...目的分析副溶血弧菌O10:K4血清型O抗原基因簇的分子特征,并构建基于基因组的分子血清型预测数据库。方法从美国国家生物技术信息中心Assembly数据库获取副溶血弧菌O抗原基因簇序列,使用blastn、fastANI、Sourmash和p i x y工具分析序列相似性和多态性,使用g u b b i n s进行重组分析,并构建了副溶血弧菌分子血清型预测数据库。结果O10:K4的O抗原基因簇(OL10V1)与传统O10血清型基因簇(OL10)序列差异显著,而与OL4最为相似。公共数据库中116个OL10V1全长序列仅存在1个单核苷酸突变。OL10V1携带的IS1634和ISVa2转座酶基因广泛分布于弧菌属,提示该变异体可能通过水平基因转移形成。结论本研究揭示了O10:K4血清型快速传播的潜在分子机制,构建的分子血清型数据库可为基因组监测和溯源提供关键技术支撑。展开更多
基金supported by the National Key R&D Program of China(Grant No.2020YFA0713100)National Natural Science Foundation of China(Grant Nos.12141104 and 12431004)+3 种基金supported by National Natural Science Foundation of China(Grant Nos.12371059 and 12431004)Jiangsu Specially-Appointed Professor ProgramFundamental Research Funds for the Central UniversitiesSpecial Priority Program SPP 2026“Geometry at Infinity”from the German Research Foundation(DFG)。
文摘In this paper,we first prove the openness theorems on convergence of the twisted Kähler-Ricci flows.Then as applications,we improve Perelman's estimates along the twisted Kähler-Ricci flows and give criteria for the convergence of twisted Kähler-Ricci flows in relation to the greatest twisted Ricci lower bound,which gives a geometric interpretation of the greatest twisted Ricci lower bound from the viewpoint of geometric flows.
文摘目的分析副溶血弧菌O10:K4血清型O抗原基因簇的分子特征,并构建基于基因组的分子血清型预测数据库。方法从美国国家生物技术信息中心Assembly数据库获取副溶血弧菌O抗原基因簇序列,使用blastn、fastANI、Sourmash和p i x y工具分析序列相似性和多态性,使用g u b b i n s进行重组分析,并构建了副溶血弧菌分子血清型预测数据库。结果O10:K4的O抗原基因簇(OL10V1)与传统O10血清型基因簇(OL10)序列差异显著,而与OL4最为相似。公共数据库中116个OL10V1全长序列仅存在1个单核苷酸突变。OL10V1携带的IS1634和ISVa2转座酶基因广泛分布于弧菌属,提示该变异体可能通过水平基因转移形成。结论本研究揭示了O10:K4血清型快速传播的潜在分子机制,构建的分子血清型数据库可为基因组监测和溯源提供关键技术支撑。
