This study integrates multiple sources of data(transaction data,policy text,public opinion data)with visualization techniques(such as heat maps,time-series trend charts,3D building brochures)to construct an analysis f...This study integrates multiple sources of data(transaction data,policy text,public opinion data)with visualization techniques(such as heat maps,time-series trend charts,3D building brochures)to construct an analysis framework for the Chengdu real estate market.By using the Adaptive Neuro-Fuzzy Inference System(ANFIS)prediction model,spatial GIS(Geographic Information System analysis)analysis,and interactive dashboards,this study reveals market differentiation,policy impacts,and changes in demand structure,thereby providing decision support for the government,enterprises,and homebuyers.展开更多
With people living longer,the societal impact of age-related cognitive decline is becoming more pronounced(Crimmins,2015).Thus,it is increasingly important to comprehend the cognitive shifts linked to aging-whether th...With people living longer,the societal impact of age-related cognitive decline is becoming more pronounced(Crimmins,2015).Thus,it is increasingly important to comprehend the cognitive shifts linked to aging-whether they are physiological or pathological.展开更多
Very long chain-saturated and-polyunsaturated fatty acids(VLC-SFA and VLC-PUFA, respectively) are a functionally important class of fatty acids containing 28 carbons or more in their acyl chain. They are synthesized b...Very long chain-saturated and-polyunsaturated fatty acids(VLC-SFA and VLC-PUFA, respectively) are a functionally important class of fatty acids containing 28 carbons or more in their acyl chain. They are synthesized by the elongation of very long fatty acids-4(ELOVL4) enzyme, expressed mainly in the brain, retina, skin, testes, and meibomian gland, where these fatty acids are found(Agbaga et al., 2008). Further, these organs exhibit tissuespecific VLC-PUFA and VLC-SFA biosynthesis and incorporation into complex lipids for specific functions. In the brain, skin, and Meibomian glands, the ELOVL4 mainly makes VLC-SFA, which are incorporated into complex sphingolipids. In the retina, the ELOVL4 makes VLC-PUFA that are incorporated into phosphatidylcholine, that are critical for visual function, while in testes and sperm, the VLC-PUFA are incorporated into sphingolipids that are critical for fertility(Yeboah et al., 2021).展开更多
The electrocatalytic urea oxidation reaction(UOR)has emerged as an energy-efficient alternative to the traditional oxygen evolution reaction for hydrogen production,with mechanistic understanding being critical for th...The electrocatalytic urea oxidation reaction(UOR)has emerged as an energy-efficient alternative to the traditional oxygen evolution reaction for hydrogen production,with mechanistic understanding being critical for the rational design of catalysts.This review systematically summarizes recent advances in in situ characterization techniques for elucidating the dynamic reaction mechanisms of UOR.Studies reveal that phase transitions,valence state migration,and electronic structure evolution of catalysts under operational conditions are key factors governing activity and stability.Techniques such as in situ X-ray diffraction,X-ray absorption spectroscopy,Raman spectroscopy,and Fourier-transform infrared spectroscopy enable real-time monitoring of catalyst reconstruction,intermediate evolution,and interfacial adsorption behavior,overcoming the environmental deviations inherent in conventional ex situ characterization.When combined with theoretical calculations,these methods provide direct evidence for identifying active-site configurations,reaction pathways,and rate-determining steps.In addition,special emphasis is placed on multimodal in situ strategies for deciphering synergistic effects in nickel-based catalysts,while current challenges,including non-alkaline systems,real wastewater environments,and multi-metal cooperation mechanisms,are critically discussed.Future research should focus on developing novel in situ approaches for complex systems and establishing a mutually reinforcing framework integrating theoretical prediction and experimental validation,thereby advancing UOR catalyst design from empirical exploration to mechanism-guided optimization.展开更多
The InSight mission has obtained seismic data from Mars,offering new insights into the planet’s internal structure and seismic activity.However,the raw data released to the public contain various sources of noise,suc...The InSight mission has obtained seismic data from Mars,offering new insights into the planet’s internal structure and seismic activity.However,the raw data released to the public contain various sources of noise,such as ticks and glitches,which hamper further seismological studies.This paper presents step-by-step processing of InSight’s Very Broad Band seismic data,focusing on the suppression and removal of non-seismic noise.The processing stages include tick noise removal,glitch signal suppression,multicomponent synchronization,instrument response correction,and rotation of orthogonal components.The processed datasets and associated codes are openly accessible and will support ongoing efforts to explore the geophysical properties of Mars and contribute to the broader field of planetary seismology.展开更多
When attending a symposium on private businesses on 17 February,Chinese President Xi Jinping underscored the immense opportunities within China’s private economy.He stated that the private sector enjoys broad prospec...When attending a symposium on private businesses on 17 February,Chinese President Xi Jinping underscored the immense opportunities within China’s private economy.He stated that the private sector enjoys broad prospects and great potential on the new journey in the new era,and that it is a prime time for private businesses and entrepreneurs to give full play to their capabilities.展开更多
Autophagy plays a crucial role in axon regeneration by maintaining cellular homeostasis and promoting the clearance of damaged organelles and proteins,which is essential for the growth and repair of axons.In response ...Autophagy plays a crucial role in axon regeneration by maintaining cellular homeostasis and promoting the clearance of damaged organelles and proteins,which is essential for the growth and repair of axons.In response to axonal injury,autophagy is upregulated to facilitate the removal of cellular debris and support the recycling of essential components needed for regeneration.展开更多
Symbiotic nitrogen fixation in members of the Fabaceae family is highly efficient and beneficial for global agriculture,but not all species in this family form root nodules with rhizobial bacteria.Nodulation mainly oc...Symbiotic nitrogen fixation in members of the Fabaceae family is highly efficient and beneficial for global agriculture,but not all species in this family form root nodules with rhizobial bacteria.Nodulation mainly occurs in plants belonging to the Papilionoideae and Caesalpinioideae subfamilies(Tederso0 et al.,2018;van Velzen et al.,2019).Nodulation mechanisms in Fabaceae are well studied(Yang et al.,2022),and genomic comparisons of nodulating and non-nodulating host species can provide valuable insights into the evolutionary and genetic basis of this key process.展开更多
The objectives of this qualitative research were:(a)to analyze the challenges faced by English literature teachers in teaching English through literature curriculum in English as a foreign language(EFL)classrooms of M...The objectives of this qualitative research were:(a)to analyze the challenges faced by English literature teachers in teaching English through literature curriculum in English as a foreign language(EFL)classrooms of Myanmar;and(b)to examine the insights from stakeholders towards teaching English through literature curriculum in EFL classrooms of Myanmar.The samples were composed of 27 English literature teachers from specific Arts and Science Universities,six government officials and three local business leaders.They were selected through a purposive sampling method.The research conducted through a semi-structured interview,classroom observation,and focus group discussion.Content analysis and document analysis were used to analyze the data.The findings suggest that challenges can be categorized into three groups:student-related,teacher-related,and external factors.Additionally,the study highlights the importance of students’language proficiency,linguistic,and stylistic complexity of texts,and cultural familiarity in influencing the teaching-learning process.The results contribute to a better understanding of the challenges faced by English literature teachers in Myanmar,offering insights for the improvement of teaching practices in this context.展开更多
Iread with great interest the recent article by Shin,et al.[1]the authors present an important exploration into the use of drug-coated balloon(DCB)in patients aged≥75 years,a demographic increasingly encountered in m...Iread with great interest the recent article by Shin,et al.[1]the authors present an important exploration into the use of drug-coated balloon(DCB)in patients aged≥75 years,a demographic increasingly encountered in modern cardiovascular practice.The authors conducted a retrospective analysis involving 2050 elderly patients(aged≥75 years)undergoing successful percutaneous coronary intervention(PCI).展开更多
In recent years,with the increasing attention to issues related to carbon emissions,such as carbon tariffs and government netzero carbon emission policies,carbon emissions have become an important indicator that is be...In recent years,with the increasing attention to issues related to carbon emissions,such as carbon tariffs and government netzero carbon emission policies,carbon emissions have become an important indicator that is being prioritized by governments worldwide.The Google Environmental Insights Explorer(EIE)tool has been developed to facilitate the collection and integration of data in this context.This study focuses on Tainan City and utilizes EIE to analyze greenhouse gas emissions from transportation.By using EIE,the study obtains data on greenhouse gas emissions from transportation activities in Tainan City.EIE utilizes data collected by Google and simulation functions to estimate data based on actual measurements of transportation activities.This tool saves time and resources by eliminating the need for on-site investigations while providing data that closely represent the real emissions from transportation activities in urban areas.Transportation vehicles contribute to greenhouse gas emissions in two ways:through direct combustion of fossil fuels and through the consumption of electricity in electric vehicles(EVs).The level of greenhouse gas emissions in a city’s transportation industry depends on factors such as transportation modes,fuel types,fleet age and energy efficiency,total distance traveled,and annual mileage.EIE estimates the greenhouse gas emissions from Tainan City’s transportation industry in 2022 to be 3,320,000 metric tons,including emissions from buses,motorcycles,cars,walking,railways,bicycles,and other modes of transportation.展开更多
The donkey is an important livestock species that can provide milk,meat,and skin and belongs to the family Equus.The first genome of a male donkey was sequenced and de novo assembled using a whole-genome shotgun strat...The donkey is an important livestock species that can provide milk,meat,and skin and belongs to the family Equus.The first genome of a male donkey was sequenced and de novo assembled using a whole-genome shotgun strategy(Huang et al.,2015).Subsequently,the donkey genome showed greater improvement in continuity and chromosome length than a previous assembly(Renaud et al.,2018).展开更多
Lithium-ion batteries are at the forefront of modern energy storage technology.However,the accumulation of by-products such as ethylene and carbon dioxide during charging and discharging cycles reduces battery effecti...Lithium-ion batteries are at the forefront of modern energy storage technology.However,the accumulation of by-products such as ethylene and carbon dioxide during charging and discharging cycles reduces battery effective capacity and threatens large-scale safe performance.With significant advantages over ethylene carbonate(EC)electrolytes,fluorinated electrolytes can more effectively suppress internal gas evolution,thereby improving battery safety and cycling stability.To reveal the mechanism behind gas formation in lithium-ion batteries,our study investigated the transport behavior and interfacial products of fluorinated electrolytes under various operation conditions,including electrode material and electrolyte composition.Innovatively,we applied the reaction network integrator ReacNetGenerator to the analysis of the solid electrolyte interface(SEI)in lithium batteries,providing more molecular fingerprint information from the perspective of specific products.Using reactive molecular dynamics(MD)simulations with the ReaxFF force field and EChemDID,complemented by density functional theory(DFT)calculations,our results demonstrate that fluorinated electrolytes can effectively suppress the decomposition of LiPF_(6) to produce toxic gases PFs and PF_3.DFT analysis further reveals that highly fluorinated solvents(e.g.,FEMC)enhance the anti-reduction stability of PF_(6)~-through synergistic regulation of molecular orbital energy levels,thermodynamic electron affinity,charge transfer,and electrostatic potential distribution,thereby mitigating LiPF_(6) decomposition.Additionally,fluorinated electrolytes generate significantly more LiF components than non-fluorinated ones to promote the formation of a stable and durable solid electrolyte interface(SEI).Experimental validations via XPS and GC-MS confirm reduced CO_(2) generation and LiF-enriched SEI formation,aligning with simulation and DFT data.The findings provide valuable insights for the design of advanced electrolytes aimed at ensuring large-scale,safe energy storage solutions.展开更多
基金Chengdu City Philosophy and Social Sciences Research Center“artificial intelligence+urban communication”theory and Application Research Center Project“Chengdu real estate vertical market public opinion data visualization research”(Project No.RZCC2025017).
文摘This study integrates multiple sources of data(transaction data,policy text,public opinion data)with visualization techniques(such as heat maps,time-series trend charts,3D building brochures)to construct an analysis framework for the Chengdu real estate market.By using the Adaptive Neuro-Fuzzy Inference System(ANFIS)prediction model,spatial GIS(Geographic Information System analysis)analysis,and interactive dashboards,this study reveals market differentiation,policy impacts,and changes in demand structure,thereby providing decision support for the government,enterprises,and homebuyers.
基金Clévio Nóbrega’s laboratory is funded by the Cure CSB projectthe Viljem Julijan Association for Children with Rare Diseases(Slovenia)+1 种基金the Algarve Biomedical Center Research Institute(ABC-Ri)funded by CRESC Algarve 2020(Operation Code:ALG-01-0145-FEDER-072586)(to CN)。
文摘With people living longer,the societal impact of age-related cognitive decline is becoming more pronounced(Crimmins,2015).Thus,it is increasingly important to comprehend the cognitive shifts linked to aging-whether they are physiological or pathological.
基金supported by NEI/NIH R01 EY030513NIAMS/NIH R21-AR076035Multi-PI Team Science grant from Presbyterian Health Foundation。
文摘Very long chain-saturated and-polyunsaturated fatty acids(VLC-SFA and VLC-PUFA, respectively) are a functionally important class of fatty acids containing 28 carbons or more in their acyl chain. They are synthesized by the elongation of very long fatty acids-4(ELOVL4) enzyme, expressed mainly in the brain, retina, skin, testes, and meibomian gland, where these fatty acids are found(Agbaga et al., 2008). Further, these organs exhibit tissuespecific VLC-PUFA and VLC-SFA biosynthesis and incorporation into complex lipids for specific functions. In the brain, skin, and Meibomian glands, the ELOVL4 mainly makes VLC-SFA, which are incorporated into complex sphingolipids. In the retina, the ELOVL4 makes VLC-PUFA that are incorporated into phosphatidylcholine, that are critical for visual function, while in testes and sperm, the VLC-PUFA are incorporated into sphingolipids that are critical for fertility(Yeboah et al., 2021).
文摘The electrocatalytic urea oxidation reaction(UOR)has emerged as an energy-efficient alternative to the traditional oxygen evolution reaction for hydrogen production,with mechanistic understanding being critical for the rational design of catalysts.This review systematically summarizes recent advances in in situ characterization techniques for elucidating the dynamic reaction mechanisms of UOR.Studies reveal that phase transitions,valence state migration,and electronic structure evolution of catalysts under operational conditions are key factors governing activity and stability.Techniques such as in situ X-ray diffraction,X-ray absorption spectroscopy,Raman spectroscopy,and Fourier-transform infrared spectroscopy enable real-time monitoring of catalyst reconstruction,intermediate evolution,and interfacial adsorption behavior,overcoming the environmental deviations inherent in conventional ex situ characterization.When combined with theoretical calculations,these methods provide direct evidence for identifying active-site configurations,reaction pathways,and rate-determining steps.In addition,special emphasis is placed on multimodal in situ strategies for deciphering synergistic effects in nickel-based catalysts,while current challenges,including non-alkaline systems,real wastewater environments,and multi-metal cooperation mechanisms,are critically discussed.Future research should focus on developing novel in situ approaches for complex systems and establishing a mutually reinforcing framework integrating theoretical prediction and experimental validation,thereby advancing UOR catalyst design from empirical exploration to mechanism-guided optimization.
基金supported by the National Key R&D Program of China(Nos.2022YFF 0503203 and 2024YFF0809900)the Research Funds of the Institute of Geophysics,China Earthquake Administration(No.DQJB24X28)the National Natural Science Foundation of China(Nos.42474226 and 42441827).
文摘The InSight mission has obtained seismic data from Mars,offering new insights into the planet’s internal structure and seismic activity.However,the raw data released to the public contain various sources of noise,such as ticks and glitches,which hamper further seismological studies.This paper presents step-by-step processing of InSight’s Very Broad Band seismic data,focusing on the suppression and removal of non-seismic noise.The processing stages include tick noise removal,glitch signal suppression,multicomponent synchronization,instrument response correction,and rotation of orthogonal components.The processed datasets and associated codes are openly accessible and will support ongoing efforts to explore the geophysical properties of Mars and contribute to the broader field of planetary seismology.
文摘When attending a symposium on private businesses on 17 February,Chinese President Xi Jinping underscored the immense opportunities within China’s private economy.He stated that the private sector enjoys broad prospects and great potential on the new journey in the new era,and that it is a prime time for private businesses and entrepreneurs to give full play to their capabilities.
文摘Autophagy plays a crucial role in axon regeneration by maintaining cellular homeostasis and promoting the clearance of damaged organelles and proteins,which is essential for the growth and repair of axons.In response to axonal injury,autophagy is upregulated to facilitate the removal of cellular debris and support the recycling of essential components needed for regeneration.
基金supported by the National Natural Science Foundation of China(No.32160142)Guangxi Natural Science Foundation(No.2023GXNSFDA026034)+3 种基金State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources(SKLCUSAb202302)to H.W.,the National Natural Science Foundation of China(No.32460062)to Y.L.,and 1+9 Leading the Charge with Open Competition'project of Sichuan Academy of Agricultural Sciences(1+9KJGG010)Fruit tree breeding project in Sichuan Province(2021YFYZ0023)to H.X.
文摘Symbiotic nitrogen fixation in members of the Fabaceae family is highly efficient and beneficial for global agriculture,but not all species in this family form root nodules with rhizobial bacteria.Nodulation mainly occurs in plants belonging to the Papilionoideae and Caesalpinioideae subfamilies(Tederso0 et al.,2018;van Velzen et al.,2019).Nodulation mechanisms in Fabaceae are well studied(Yang et al.,2022),and genomic comparisons of nodulating and non-nodulating host species can provide valuable insights into the evolutionary and genetic basis of this key process.
文摘The objectives of this qualitative research were:(a)to analyze the challenges faced by English literature teachers in teaching English through literature curriculum in English as a foreign language(EFL)classrooms of Myanmar;and(b)to examine the insights from stakeholders towards teaching English through literature curriculum in EFL classrooms of Myanmar.The samples were composed of 27 English literature teachers from specific Arts and Science Universities,six government officials and three local business leaders.They were selected through a purposive sampling method.The research conducted through a semi-structured interview,classroom observation,and focus group discussion.Content analysis and document analysis were used to analyze the data.The findings suggest that challenges can be categorized into three groups:student-related,teacher-related,and external factors.Additionally,the study highlights the importance of students’language proficiency,linguistic,and stylistic complexity of texts,and cultural familiarity in influencing the teaching-learning process.The results contribute to a better understanding of the challenges faced by English literature teachers in Myanmar,offering insights for the improvement of teaching practices in this context.
文摘Iread with great interest the recent article by Shin,et al.[1]the authors present an important exploration into the use of drug-coated balloon(DCB)in patients aged≥75 years,a demographic increasingly encountered in modern cardiovascular practice.The authors conducted a retrospective analysis involving 2050 elderly patients(aged≥75 years)undergoing successful percutaneous coronary intervention(PCI).
文摘In recent years,with the increasing attention to issues related to carbon emissions,such as carbon tariffs and government netzero carbon emission policies,carbon emissions have become an important indicator that is being prioritized by governments worldwide.The Google Environmental Insights Explorer(EIE)tool has been developed to facilitate the collection and integration of data in this context.This study focuses on Tainan City and utilizes EIE to analyze greenhouse gas emissions from transportation.By using EIE,the study obtains data on greenhouse gas emissions from transportation activities in Tainan City.EIE utilizes data collected by Google and simulation functions to estimate data based on actual measurements of transportation activities.This tool saves time and resources by eliminating the need for on-site investigations while providing data that closely represent the real emissions from transportation activities in urban areas.Transportation vehicles contribute to greenhouse gas emissions in two ways:through direct combustion of fossil fuels and through the consumption of electricity in electric vehicles(EVs).The level of greenhouse gas emissions in a city’s transportation industry depends on factors such as transportation modes,fuel types,fleet age and energy efficiency,total distance traveled,and annual mileage.EIE estimates the greenhouse gas emissions from Tainan City’s transportation industry in 2022 to be 3,320,000 metric tons,including emissions from buses,motorcycles,cars,walking,railways,bicycles,and other modes of transportation.
基金supported by the Third National Census of Livestock and Poultry Genetic Resources(K4050422227)the 2020 Scientist plus Engineer program of Shaanxi Province of Chinathe Central Guidance on Local Science and Technology Development Fund(K3030922098).
文摘The donkey is an important livestock species that can provide milk,meat,and skin and belongs to the family Equus.The first genome of a male donkey was sequenced and de novo assembled using a whole-genome shotgun strategy(Huang et al.,2015).Subsequently,the donkey genome showed greater improvement in continuity and chromosome length than a previous assembly(Renaud et al.,2018).
基金funding support from the National Natural Science Foundation of China(Grant No.52302302)the National Key R&D Program of China(Grant No.2022YFE0208000)+1 种基金the Fundamental Research Funds for the Central Universitiesthe Special Funds of Tongji University for“Sino-German Cooperation 2.0 Strategy”。
文摘Lithium-ion batteries are at the forefront of modern energy storage technology.However,the accumulation of by-products such as ethylene and carbon dioxide during charging and discharging cycles reduces battery effective capacity and threatens large-scale safe performance.With significant advantages over ethylene carbonate(EC)electrolytes,fluorinated electrolytes can more effectively suppress internal gas evolution,thereby improving battery safety and cycling stability.To reveal the mechanism behind gas formation in lithium-ion batteries,our study investigated the transport behavior and interfacial products of fluorinated electrolytes under various operation conditions,including electrode material and electrolyte composition.Innovatively,we applied the reaction network integrator ReacNetGenerator to the analysis of the solid electrolyte interface(SEI)in lithium batteries,providing more molecular fingerprint information from the perspective of specific products.Using reactive molecular dynamics(MD)simulations with the ReaxFF force field and EChemDID,complemented by density functional theory(DFT)calculations,our results demonstrate that fluorinated electrolytes can effectively suppress the decomposition of LiPF_(6) to produce toxic gases PFs and PF_3.DFT analysis further reveals that highly fluorinated solvents(e.g.,FEMC)enhance the anti-reduction stability of PF_(6)~-through synergistic regulation of molecular orbital energy levels,thermodynamic electron affinity,charge transfer,and electrostatic potential distribution,thereby mitigating LiPF_(6) decomposition.Additionally,fluorinated electrolytes generate significantly more LiF components than non-fluorinated ones to promote the formation of a stable and durable solid electrolyte interface(SEI).Experimental validations via XPS and GC-MS confirm reduced CO_(2) generation and LiF-enriched SEI formation,aligning with simulation and DFT data.The findings provide valuable insights for the design of advanced electrolytes aimed at ensuring large-scale,safe energy storage solutions.
