腹泻型肠易激综合征(Irritable Bowel Syndrome with Diarrhea,IBS-D)是一种常见的功能性胃肠病,以反复发作的腹痛、腹胀、腹泻为核心症状,常伴随焦虑、抑郁等心理问题。低FODMAP饮食通过限制难吸收碳水化合物,可减少肠道产气与刺激,有...腹泻型肠易激综合征(Irritable Bowel Syndrome with Diarrhea,IBS-D)是一种常见的功能性胃肠病,以反复发作的腹痛、腹胀、腹泻为核心症状,常伴随焦虑、抑郁等心理问题。低FODMAP饮食通过限制难吸收碳水化合物,可减少肠道产气与刺激,有效缓解IBS-D腹泻症状;微正念训练则能调节自主神经功能,减轻焦虑情绪,改善脑-肠轴失衡。COM-B模型(CaPability-OPPortunity-Motivation-Behavior)从能力、机会、动机三个维度解析行为改变机制,为多维度干预方案的构建提供了科学框架。本研究基于COM-B模型,整合微正念训练与低FODMAP饮食指导,构建协同干预方案,通过精准识别患者行为改变障碍,实现个性化干预,旨在为IBS-D患者提供更有效的非药物干预策略。现将效果分析如下。展开更多
目的:研究香苏通降散联合揿针疗法对IBS-D (脾胃虚弱证)的效果及血浆中血管活性肠肽(VIP)及P成分(SP)的改变,进一步探究其机制。方式:共纳入60例符合IBSD (腹泻型肠易激综合征)脾胃虚弱证入选标准的病人,随机数字表法分为香苏通降散联...目的:研究香苏通降散联合揿针疗法对IBS-D (脾胃虚弱证)的效果及血浆中血管活性肠肽(VIP)及P成分(SP)的改变,进一步探究其机制。方式:共纳入60例符合IBSD (腹泻型肠易激综合征)脾胃虚弱证入选标准的病人,随机数字表法分为香苏通降散联合揿针疗法(治疗组)和匹维溴铵片疗法组(对照组),每组各30例,以4周为1星期,在治愈前后检查两组病人主要症状评估、血浆VIP及SP水平,并作出效果评估。结论:(1) 治疗前两组之间的病症总分数对比,无统计学差异,存在一致性;治疗后两组间的病症总分数对比,临床治疗组小于对照组(P Objective: To study the effects of Xiangsu Tong Jiangsan combined with press needle therapy on IBS-D (spleen and stomach weakness syndrome) and the changes in plasma vascular active intestinal peptide (VIP) and P component (SP), further exploring its mechanism. Methods: A total of 60 patients meeting the criteria for IBS-D (Diarrhea Type Irritable Bowel Syndrome) with spleen and stomach weakness syndrome were included, randomly divided into Xiangsu Tong Jiangsan combined with press needle therapy (treatment group) and pivabromide tablets therapy group (control group), with 30 cases in each group, evaluated for main symptom assessment and plasma VIP and SP levels before and after 4 weeks of treatment, and assessed the effectiveness. Conclusion: (1) There was no statistically significant difference in the total symptom scores between the two groups before treatment, indicating consistency;after treatment, the total symptom scores of the clinical treatment group were significantly lower than those of the control group (P < 0.05), showing statistically significant differences. (2) After treatment, the VIP and SP levels of both groups of patients significantly increased. Over 4 weeks of observation, the differences between the two groups were highly significant, indicating that both the treatment group and the control group achieved good results. Overall, the conditions of both groups of patients significantly improved, with the treatment group performing better than the control group. Conclusion: Xiangsu Tong Jiangsan combined with press needle therapy can effectively treat diarrhea type irritable bowel syndrome (spleen and stomach weakness syndrome), significantly improving patient symptoms and serum VIP and SP levels, making it worthy of clinical promotion and application.展开更多
文摘腹泻型肠易激综合征(Irritable Bowel Syndrome with Diarrhea,IBS-D)是一种常见的功能性胃肠病,以反复发作的腹痛、腹胀、腹泻为核心症状,常伴随焦虑、抑郁等心理问题。低FODMAP饮食通过限制难吸收碳水化合物,可减少肠道产气与刺激,有效缓解IBS-D腹泻症状;微正念训练则能调节自主神经功能,减轻焦虑情绪,改善脑-肠轴失衡。COM-B模型(CaPability-OPPortunity-Motivation-Behavior)从能力、机会、动机三个维度解析行为改变机制,为多维度干预方案的构建提供了科学框架。本研究基于COM-B模型,整合微正念训练与低FODMAP饮食指导,构建协同干预方案,通过精准识别患者行为改变障碍,实现个性化干预,旨在为IBS-D患者提供更有效的非药物干预策略。现将效果分析如下。
文摘目的:研究香苏通降散联合揿针疗法对IBS-D (脾胃虚弱证)的效果及血浆中血管活性肠肽(VIP)及P成分(SP)的改变,进一步探究其机制。方式:共纳入60例符合IBSD (腹泻型肠易激综合征)脾胃虚弱证入选标准的病人,随机数字表法分为香苏通降散联合揿针疗法(治疗组)和匹维溴铵片疗法组(对照组),每组各30例,以4周为1星期,在治愈前后检查两组病人主要症状评估、血浆VIP及SP水平,并作出效果评估。结论:(1) 治疗前两组之间的病症总分数对比,无统计学差异,存在一致性;治疗后两组间的病症总分数对比,临床治疗组小于对照组(P Objective: To study the effects of Xiangsu Tong Jiangsan combined with press needle therapy on IBS-D (spleen and stomach weakness syndrome) and the changes in plasma vascular active intestinal peptide (VIP) and P component (SP), further exploring its mechanism. Methods: A total of 60 patients meeting the criteria for IBS-D (Diarrhea Type Irritable Bowel Syndrome) with spleen and stomach weakness syndrome were included, randomly divided into Xiangsu Tong Jiangsan combined with press needle therapy (treatment group) and pivabromide tablets therapy group (control group), with 30 cases in each group, evaluated for main symptom assessment and plasma VIP and SP levels before and after 4 weeks of treatment, and assessed the effectiveness. Conclusion: (1) There was no statistically significant difference in the total symptom scores between the two groups before treatment, indicating consistency;after treatment, the total symptom scores of the clinical treatment group were significantly lower than those of the control group (P < 0.05), showing statistically significant differences. (2) After treatment, the VIP and SP levels of both groups of patients significantly increased. Over 4 weeks of observation, the differences between the two groups were highly significant, indicating that both the treatment group and the control group achieved good results. Overall, the conditions of both groups of patients significantly improved, with the treatment group performing better than the control group. Conclusion: Xiangsu Tong Jiangsan combined with press needle therapy can effectively treat diarrhea type irritable bowel syndrome (spleen and stomach weakness syndrome), significantly improving patient symptoms and serum VIP and SP levels, making it worthy of clinical promotion and application.
