case of hyper plastic arthritis of knee received the treatment of manipulations, herbal steaming and washing and hot compression as well. The shortest course of disease was 3 months and the longest one was 10 years. T...case of hyper plastic arthritis of knee received the treatment of manipulations, herbal steaming and washing and hot compression as well. The shortest course of disease was 3 months and the longest one was 10 years. The manipulative steps were as follows: thumb kneading and pressing around the knee; finger nipping the knee eye point; palm kneading around the knee; then articulation kneading the patella and finally pulling and pushing the knee joint. The whole process was repeated 3 to 5 times. The treatment was given every 2 or 3 days with 20 times in one course. The herbal formula for steaming and washing was composed of around 15 herbs which were decocted together. A small amount of wine was added into the hot decoction to steam and wash the affected knee. Then the dregs of the decoction were put into a cloth made bag and an appropriate amount of wine and water were added into it. After heated the bag was topically compressed onto the affected knee. The treatment was given once or twice daily with 10 times in one course. The result showed that 60 cases were cured, 20 markedly improved, 32 only improved and 6 failed to respond to the treatment. The total effective rate reached 94.92%. The shortest time for treatment was one month while the longest one was three.展开更多
A standardized extract of the plant Caralluma fimbriata (Slimaluma?) is widely used in the management of obesity but its mode of action is not yet clarified. This study investigated the ability of Caralluma fimbriata ...A standardized extract of the plant Caralluma fimbriata (Slimaluma?) is widely used in the management of obesity but its mode of action is not yet clarified. This study investigated the ability of Caralluma fimbriata extract (CFE) to modify pre-adipocyte cell division and thus the development of hyper-plastic obesity. Mouse 3T3-L1 pre-adipocyte cell line samples were treated with different concentrations of an extract of CFE standardized against its pregnane glycoside content. Plain medium formed the negative control and hydroxyurea was the positive control. The cells were counted at 12-hour intervals, and their viability tested using the MTT assay. The treated cells were subjected to direct and indirect immunofluorescent assays for cyclin D1. CFE inhibited 3T3-L1 cell growth in a dose and duration-dependent manner, with results comparable to those produced by hydroxyurea. The viability of CFE-treated cells was reduced. Direct and indirect immunofluorescent assays demonstrated that CFE inhibits import of cyclin D1into the nucleus. CFE appears to inhibit pre-adipocyte cell division by interfering with a mechanism preceding the import of cyclin D1-CDk4/6 complex into the nucleus during the early G1 phase of the cell cycle, suggesting that CFE has the potential to inhibit hyperplastic obesity.展开更多
文摘case of hyper plastic arthritis of knee received the treatment of manipulations, herbal steaming and washing and hot compression as well. The shortest course of disease was 3 months and the longest one was 10 years. The manipulative steps were as follows: thumb kneading and pressing around the knee; finger nipping the knee eye point; palm kneading around the knee; then articulation kneading the patella and finally pulling and pushing the knee joint. The whole process was repeated 3 to 5 times. The treatment was given every 2 or 3 days with 20 times in one course. The herbal formula for steaming and washing was composed of around 15 herbs which were decocted together. A small amount of wine was added into the hot decoction to steam and wash the affected knee. Then the dregs of the decoction were put into a cloth made bag and an appropriate amount of wine and water were added into it. After heated the bag was topically compressed onto the affected knee. The treatment was given once or twice daily with 10 times in one course. The result showed that 60 cases were cured, 20 markedly improved, 32 only improved and 6 failed to respond to the treatment. The total effective rate reached 94.92%. The shortest time for treatment was one month while the longest one was three.
文摘A standardized extract of the plant Caralluma fimbriata (Slimaluma?) is widely used in the management of obesity but its mode of action is not yet clarified. This study investigated the ability of Caralluma fimbriata extract (CFE) to modify pre-adipocyte cell division and thus the development of hyper-plastic obesity. Mouse 3T3-L1 pre-adipocyte cell line samples were treated with different concentrations of an extract of CFE standardized against its pregnane glycoside content. Plain medium formed the negative control and hydroxyurea was the positive control. The cells were counted at 12-hour intervals, and their viability tested using the MTT assay. The treated cells were subjected to direct and indirect immunofluorescent assays for cyclin D1. CFE inhibited 3T3-L1 cell growth in a dose and duration-dependent manner, with results comparable to those produced by hydroxyurea. The viability of CFE-treated cells was reduced. Direct and indirect immunofluorescent assays demonstrated that CFE inhibits import of cyclin D1into the nucleus. CFE appears to inhibit pre-adipocyte cell division by interfering with a mechanism preceding the import of cyclin D1-CDk4/6 complex into the nucleus during the early G1 phase of the cell cycle, suggesting that CFE has the potential to inhibit hyperplastic obesity.
