Objective To search for effective methods of acupuncture therapy in treating chronic diarrhea. Methods Treatments were carried out on 52 patients with chronic diarrhea by using the left ascending and right descending ...Objective To search for effective methods of acupuncture therapy in treating chronic diarrhea. Methods Treatments were carried out on 52 patients with chronic diarrhea by using the left ascending and right descending method. Three acupoints at the left side, namely Xiàng （陷谷 ST 43）, Zúsānl （足三 里 ST 36） and Qūchí （曲池 LI 11）, and Lièqūe （列缺 LU 7） at the right side were selected, moxibustion was also carried out according to syndrome differentiation. The operation of left ascending and right descending method were firstly left and then right, first down and then up, firstly four limbs and then abdomen; the thumb moved backward and the index finger moved forward during needle twisting for the acupoints at the left side, and it was on the contrary for the right side. The needles were retained for 1 h for deficiency, and the pinholes were pressed when the needles were withdrawn; the needles were retained for 0.5 h for excess syndrome and newly-contracted disease, and the pinholes were enlarged by shaking the needles when they were withdrawn. Except that the needling was carried out twice a day for the patients with desertion following chronic diarrhea, the needling was carried out once a day, five days as a treatment course, the patients were given an interval for two days after every two treatment courses, and the therapeutic effect was observed after five treatment courses. Results totally 36 patients were cured, among which 11 patients were cured after one treatment course, 19 patients were cured after two to three treatment courses and 6 patients were cured after four to five treatment courses; eight patients were improved; six patients were not cured; the total effective rate was 88.0%. Conclusion the acupuncture with left ascending and right descending method has satisfactory therapeutic effect in treating chronic diarrhea.展开更多
Objective To investigate the association between chronic pain and cognitive function in community-dwelling cancer survivors.Methods Using five waves of data from the China Health and Retirement Longitudinal Study(CHAR...Objective To investigate the association between chronic pain and cognitive function in community-dwelling cancer survivors.Methods Using five waves of data from the China Health and Retirement Longitudinal Study(CHARLS),a cohort of community-based cancer survivors was established.Baseline chronic pain status was used to classify exposure groups,and the occurrence of cognitive dysfunction was defined as the endpoint.We employed Cox proportional hazards regression models to evaluate the association between chronic pain and cognitive dysfunction.Results The study included 640 participants,with a chronic pain prevalence of 38.3%and a cognitive dysfunction incidence of 36.9%.Multivariate Cox regression demonstrated that chronic pain was independently associated with cognitive dysfunction risk(HR=1.479,95%CI:1.134-1.930).Compared to cancer survivors without pain,those with headaches(HR=1.725,95% CI:1.260-2.360),Shoulder-neck pain(HR=1.641,95%CI:1.193-2.257),and multisite pain(HR=1.653,95%CI:1.248-2.190)exhibited elevated risks.Gender-stratified analysis revealed that males with limb pain had the highest risk(HR=2.307,95% CI:1.383-3.848),while females with headaches showed the most significant risk(HR=1.903,95% CI:1.330-2.723).Stratification by chemotherapy/radiotherapy status indicated that untreated individuals with shoulder-neck pain(HR=2.040,95% CI:1.414-2.943)and multisite pain(HR=1.819,95%CI:1.281-2.392)faced higher risks,whereas treated patients with headaches had elevated cognitive dysfunction risk(HR=1.972,95%CI:1.029-3.783).Conclusion Chronic pain and cognitive dysfunction are prevalent among community-dwelling cancer survivors.Chronic pain,particularly headaches,Shoulder-neck pain,and multisite pain,is associated with increased cognitive dysfunction risk.Targeted screening and preventive measures for cognitive dysfunction are warranted in these subgroups.展开更多
Objective.To explore the expression characteristic of fibronectin gene in hypertr ophic scars and diabetic ul-cer tissues.Methods.The biopsies from normal skins,hypertrophic scars and diabetic foot ulc ers were taken....Objective.To explore the expression characteristic of fibronectin gene in hypertr ophic scars and diabetic ul-cer tissues.Methods.The biopsies from normal skins,hypertrophic scars and diabetic foot ulc ers were taken.The tech-nique of quantitative polymerase ch ain reaction(PCR)was used to evaluate the gene express ion of fibronectin in the above biopsies.Results.Fibronectin gene expression was enhanced in hypertrophic scars and decreased in diabetic foot ul-cers compared with that in normal ski ns.Quantitative comparison showed about 2-fold increase of fibronectin mR-NA level in hypertrophic scars and ab out 3-fold decrease of fibronectin mRNA level in diabetic ulcers as com-pared with that in normal skins.Conclusions.Fibronectin gene expression is influenced by the tissue environment.Di fferent expression and synthesis of fibronectin may cause d ifferent outcomes in wound healing.展开更多
文摘Objective To search for effective methods of acupuncture therapy in treating chronic diarrhea. Methods Treatments were carried out on 52 patients with chronic diarrhea by using the left ascending and right descending method. Three acupoints at the left side, namely Xiàng （陷谷 ST 43）, Zúsānl （足三 里 ST 36） and Qūchí （曲池 LI 11）, and Lièqūe （列缺 LU 7） at the right side were selected, moxibustion was also carried out according to syndrome differentiation. The operation of left ascending and right descending method were firstly left and then right, first down and then up, firstly four limbs and then abdomen; the thumb moved backward and the index finger moved forward during needle twisting for the acupoints at the left side, and it was on the contrary for the right side. The needles were retained for 1 h for deficiency, and the pinholes were pressed when the needles were withdrawn; the needles were retained for 0.5 h for excess syndrome and newly-contracted disease, and the pinholes were enlarged by shaking the needles when they were withdrawn. Except that the needling was carried out twice a day for the patients with desertion following chronic diarrhea, the needling was carried out once a day, five days as a treatment course, the patients were given an interval for two days after every two treatment courses, and the therapeutic effect was observed after five treatment courses. Results totally 36 patients were cured, among which 11 patients were cured after one treatment course, 19 patients were cured after two to three treatment courses and 6 patients were cured after four to five treatment courses; eight patients were improved; six patients were not cured; the total effective rate was 88.0%. Conclusion the acupuncture with left ascending and right descending method has satisfactory therapeutic effect in treating chronic diarrhea.
文摘Objective To investigate the association between chronic pain and cognitive function in community-dwelling cancer survivors.Methods Using five waves of data from the China Health and Retirement Longitudinal Study(CHARLS),a cohort of community-based cancer survivors was established.Baseline chronic pain status was used to classify exposure groups,and the occurrence of cognitive dysfunction was defined as the endpoint.We employed Cox proportional hazards regression models to evaluate the association between chronic pain and cognitive dysfunction.Results The study included 640 participants,with a chronic pain prevalence of 38.3%and a cognitive dysfunction incidence of 36.9%.Multivariate Cox regression demonstrated that chronic pain was independently associated with cognitive dysfunction risk(HR=1.479,95%CI:1.134-1.930).Compared to cancer survivors without pain,those with headaches(HR=1.725,95% CI:1.260-2.360),Shoulder-neck pain(HR=1.641,95%CI:1.193-2.257),and multisite pain(HR=1.653,95%CI:1.248-2.190)exhibited elevated risks.Gender-stratified analysis revealed that males with limb pain had the highest risk(HR=2.307,95% CI:1.383-3.848),while females with headaches showed the most significant risk(HR=1.903,95% CI:1.330-2.723).Stratification by chemotherapy/radiotherapy status indicated that untreated individuals with shoulder-neck pain(HR=2.040,95% CI:1.414-2.943)and multisite pain(HR=1.819,95%CI:1.281-2.392)faced higher risks,whereas treated patients with headaches had elevated cognitive dysfunction risk(HR=1.972,95%CI:1.029-3.783).Conclusion Chronic pain and cognitive dysfunction are prevalent among community-dwelling cancer survivors.Chronic pain,particularly headaches,Shoulder-neck pain,and multisite pain,is associated with increased cognitive dysfunction risk.Targeted screening and preventive measures for cognitive dysfunction are warranted in these subgroups.
文摘Objective.To explore the expression characteristic of fibronectin gene in hypertr ophic scars and diabetic ul-cer tissues.Methods.The biopsies from normal skins,hypertrophic scars and diabetic foot ulc ers were taken.The tech-nique of quantitative polymerase ch ain reaction(PCR)was used to evaluate the gene express ion of fibronectin in the above biopsies.Results.Fibronectin gene expression was enhanced in hypertrophic scars and decreased in diabetic foot ul-cers compared with that in normal ski ns.Quantitative comparison showed about 2-fold increase of fibronectin mR-NA level in hypertrophic scars and ab out 3-fold decrease of fibronectin mRNA level in diabetic ulcers as com-pared with that in normal skins.Conclusions.Fibronectin gene expression is influenced by the tissue environment.Di fferent expression and synthesis of fibronectin may cause d ifferent outcomes in wound healing.
