Objective To explore the safety and efficacy of frameless stereotactic brain biopsy.Methods Diagnostic accuracy was calculated by comparing biopsy diagnosis with definitive pathology in 62 patients who underwent frame...Objective To explore the safety and efficacy of frameless stereotactic brain biopsy.Methods Diagnostic accuracy was calculated by comparing biopsy diagnosis with definitive pathology in 62 patients who underwent frameless stereotactic brain biopsy between January 2008 and December 2010 in Xiamen University Southeast Hospital.Preoperative characteristics and histological diagnosis were reviewed and then information was analysed to identify factors associated with the biopsy not yielding a diagnosis and complications.Results Diagnostic yield was 93.5%.No differences were found between pathological diagnosis and frozen pathological diagnosis.The most common lesions were astrocytic lesions,included 16 cases of low-grade glioma and 12 cases of malignant glioma.Remote hemorrhage,metastasis,and lymphoma were following in incidence.Multiple brain lesions were found in 17 cases (27.4%).Eleven cases were frontal lesions (17.7%),8 were frontotemporal (12.9%),6 were frontoparietal (9.7%),and 5 each were temporal,parietal,and parietotemporal lesions (8.1%).Postoperative complications occurred in 21.0% of the patients after biopsies,including 10 haemorrhages (16.1%) and 3 temporary neurological deficits (1 epilepsy,1 headache,and 1 partial hemiparesis).No patient required operation for hematoma evacuation.Conclusion Frameless stereotactic biopsy is an effective and safe technique for histologic diagnosis of brain lesions,particularly for multifocal and frontal lesions.展开更多
The key technologies involved in the evolution of the Cloud-based Radio Access Network(C-RAN) are discussed in this paper. Taking the Frameless Network Architecture(FNA) as a starting point, a cell-lessbased network t...The key technologies involved in the evolution of the Cloud-based Radio Access Network(C-RAN) are discussed in this paper. Taking the Frameless Network Architecture(FNA) as a starting point, a cell-lessbased network topology for a multi-tier Heterogeneous Network(Het Net) and ultra-dense network is proposed. The FNA network topology modeling is researched with centralized processing and distributed antenna deployments. The Antenna Element(AE) is released as a new dimensional radio resource that is included in the centralized Radio Resource Management(RRM) processes. This contributes to the on-demand user-centric serving-set associations with cell-edge effect elimination. The Control Plane(CP) and User Plane(UP) separation and adaptation are introduced for energy efficiency improvements. The centralized RRM and different optimization goals are discussed for fully exploring the merits from the centralized computing of C-RAN. Considering the complexity, near-optimal approaches for specific users' Quality-of-Service(Qo S) requirements are addressed. Finally, based on the research highlighted above, the way forward of C-RAN evolution is discussed.展开更多
Objective:To analyze the therapeutic effect and prognosis of frameless stereotactic soft channel intracranial hematoma evacuation for severe basal ganglia hemorrhage.Methods:Clinical data of 411 patients with severe b...Objective:To analyze the therapeutic effect and prognosis of frameless stereotactic soft channel intracranial hematoma evacuation for severe basal ganglia hemorrhage.Methods:Clinical data of 411 patients with severe basal ganglia hemorrhage admitted to the Neurological Intensive Care Unit of Linyi People’s Hospital from January 2020 to December 2021 were collected.According to the modified Rankin Scale(mRS)score at 180 days after onset,the patients were divided into the good prognosis group and the poor prognosis group.The therapeutic effect of frameless stereotactic soft channel intracranial hematoma evacuation on severe basal ganglia hemorrhage was explored,and the influencing factors of prognosis were analyzed.Results:Multivariate Logistic regression analysis showed that the admission Glasgow Coma Scale(GCS)score was an independent protective factor for the prognosis of patients with severe basal ganglia hemorrhage,while age,preoperative hematoma volume,random blood glucose level,and mechanical ventilation were independent risk factors.Conclusion:Frameless stereotactic soft channel intracranial hematoma evacuation has a good therapeutic effect on severe basal ganglia hemorrhage.However,it is necessary to screen the patients’basic information before surgery and provide medical care based on their specific conditions to promote their rapid recovery.展开更多
目的分析不同穿刺引流术联合尿激酶注射治疗中等量高血压脑出血的疗效。方法回顾性分析2020年1月至2023年10月晋江市中医院收治的100例中等量高血压脑出血患者的临床资料,其中行CT定位锥颅血肿穿刺引流术的50例患者作为对照组,行无框架...目的分析不同穿刺引流术联合尿激酶注射治疗中等量高血压脑出血的疗效。方法回顾性分析2020年1月至2023年10月晋江市中医院收治的100例中等量高血压脑出血患者的临床资料,其中行CT定位锥颅血肿穿刺引流术的50例患者作为对照组,行无框架立体定向系统穿刺引流术的50例患者作为观察组。对比两组美国国立卫生研究院卒中量表(National Institutes of Health stroke scale,NIHSS)评分、日常生活活动能力(activity of daily living,ADL)评分、临床疗效、健康调查量表36(36-item short form health survey,SF-36)评分及并发症发生率。结果术后1周,两组NIHSS评分均低于术前,ADL评分均高于术前,且观察组NIHSS评分低于对照组,ADL评分高于对照组,差异有统计学意义(P<0.05)。观察组治疗总有效率为92.00%,高于对照组的76.00%,差异有统计学意义(P<0.05)。术后1周,两组躯体功能、精神状况、社会功能与总体健康评分均高于术前,且观察组高于对照组,差异有统计学意义(P<0.05)。观察组并发症发生率低于对照组,差异有统计学意义(P<0.05)。结论无框架立体定向系统穿刺引流术联合尿激酶注射治疗中等量高血压脑出血患者的临床疗效更优,有助于促进患者术后神经功能、日常生活活动能力恢复,可有效提升患者术后生命质量,降低减少手术相关并发症的发生风险,具有较高的临床应用价值。展开更多
文摘Objective To explore the safety and efficacy of frameless stereotactic brain biopsy.Methods Diagnostic accuracy was calculated by comparing biopsy diagnosis with definitive pathology in 62 patients who underwent frameless stereotactic brain biopsy between January 2008 and December 2010 in Xiamen University Southeast Hospital.Preoperative characteristics and histological diagnosis were reviewed and then information was analysed to identify factors associated with the biopsy not yielding a diagnosis and complications.Results Diagnostic yield was 93.5%.No differences were found between pathological diagnosis and frozen pathological diagnosis.The most common lesions were astrocytic lesions,included 16 cases of low-grade glioma and 12 cases of malignant glioma.Remote hemorrhage,metastasis,and lymphoma were following in incidence.Multiple brain lesions were found in 17 cases (27.4%).Eleven cases were frontal lesions (17.7%),8 were frontotemporal (12.9%),6 were frontoparietal (9.7%),and 5 each were temporal,parietal,and parietotemporal lesions (8.1%).Postoperative complications occurred in 21.0% of the patients after biopsies,including 10 haemorrhages (16.1%) and 3 temporary neurological deficits (1 epilepsy,1 headache,and 1 partial hemiparesis).No patient required operation for hematoma evacuation.Conclusion Frameless stereotactic biopsy is an effective and safe technique for histologic diagnosis of brain lesions,particularly for multifocal and frontal lesions.
基金supported by the National High Technology Research and Development Program of China No.2014AA01A701Nature and Science Foundation of China under Grants No.61471068,61421061+2 种基金Beijing Nova Programme No.Z131101000413030International Collaboration Project No.2015DFT10160National Major Project No.2016ZX03001009-003
文摘The key technologies involved in the evolution of the Cloud-based Radio Access Network(C-RAN) are discussed in this paper. Taking the Frameless Network Architecture(FNA) as a starting point, a cell-lessbased network topology for a multi-tier Heterogeneous Network(Het Net) and ultra-dense network is proposed. The FNA network topology modeling is researched with centralized processing and distributed antenna deployments. The Antenna Element(AE) is released as a new dimensional radio resource that is included in the centralized Radio Resource Management(RRM) processes. This contributes to the on-demand user-centric serving-set associations with cell-edge effect elimination. The Control Plane(CP) and User Plane(UP) separation and adaptation are introduced for energy efficiency improvements. The centralized RRM and different optimization goals are discussed for fully exploring the merits from the centralized computing of C-RAN. Considering the complexity, near-optimal approaches for specific users' Quality-of-Service(Qo S) requirements are addressed. Finally, based on the research highlighted above, the way forward of C-RAN evolution is discussed.
基金Shandong Provincial Medical and Health Science and Technology Development Program,Clinical Study on Modified Stereotactic Soft Channel Intracranial Hematoma Evacuation for Severe Basal Ganglia Hemorrhage(Project No.:202203071107)。
文摘Objective:To analyze the therapeutic effect and prognosis of frameless stereotactic soft channel intracranial hematoma evacuation for severe basal ganglia hemorrhage.Methods:Clinical data of 411 patients with severe basal ganglia hemorrhage admitted to the Neurological Intensive Care Unit of Linyi People’s Hospital from January 2020 to December 2021 were collected.According to the modified Rankin Scale(mRS)score at 180 days after onset,the patients were divided into the good prognosis group and the poor prognosis group.The therapeutic effect of frameless stereotactic soft channel intracranial hematoma evacuation on severe basal ganglia hemorrhage was explored,and the influencing factors of prognosis were analyzed.Results:Multivariate Logistic regression analysis showed that the admission Glasgow Coma Scale(GCS)score was an independent protective factor for the prognosis of patients with severe basal ganglia hemorrhage,while age,preoperative hematoma volume,random blood glucose level,and mechanical ventilation were independent risk factors.Conclusion:Frameless stereotactic soft channel intracranial hematoma evacuation has a good therapeutic effect on severe basal ganglia hemorrhage.However,it is necessary to screen the patients’basic information before surgery and provide medical care based on their specific conditions to promote their rapid recovery.
文摘目的分析不同穿刺引流术联合尿激酶注射治疗中等量高血压脑出血的疗效。方法回顾性分析2020年1月至2023年10月晋江市中医院收治的100例中等量高血压脑出血患者的临床资料,其中行CT定位锥颅血肿穿刺引流术的50例患者作为对照组,行无框架立体定向系统穿刺引流术的50例患者作为观察组。对比两组美国国立卫生研究院卒中量表(National Institutes of Health stroke scale,NIHSS)评分、日常生活活动能力(activity of daily living,ADL)评分、临床疗效、健康调查量表36(36-item short form health survey,SF-36)评分及并发症发生率。结果术后1周,两组NIHSS评分均低于术前,ADL评分均高于术前,且观察组NIHSS评分低于对照组,ADL评分高于对照组,差异有统计学意义(P<0.05)。观察组治疗总有效率为92.00%,高于对照组的76.00%,差异有统计学意义(P<0.05)。术后1周,两组躯体功能、精神状况、社会功能与总体健康评分均高于术前,且观察组高于对照组,差异有统计学意义(P<0.05)。观察组并发症发生率低于对照组,差异有统计学意义(P<0.05)。结论无框架立体定向系统穿刺引流术联合尿激酶注射治疗中等量高血压脑出血患者的临床疗效更优,有助于促进患者术后神经功能、日常生活活动能力恢复,可有效提升患者术后生命质量,降低减少手术相关并发症的发生风险,具有较高的临床应用价值。
