摘要
目的分析不同穿刺引流术联合尿激酶注射治疗中等量高血压脑出血的疗效。方法回顾性分析2020年1月至2023年10月晋江市中医院收治的100例中等量高血压脑出血患者的临床资料,其中行CT定位锥颅血肿穿刺引流术的50例患者作为对照组,行无框架立体定向系统穿刺引流术的50例患者作为观察组。对比两组美国国立卫生研究院卒中量表(National Institutes of Health stroke scale,NIHSS)评分、日常生活活动能力(activity of daily living,ADL)评分、临床疗效、健康调查量表36(36-item short form health survey,SF-36)评分及并发症发生率。结果术后1周,两组NIHSS评分均低于术前,ADL评分均高于术前,且观察组NIHSS评分低于对照组,ADL评分高于对照组,差异有统计学意义(P<0.05)。观察组治疗总有效率为92.00%,高于对照组的76.00%,差异有统计学意义(P<0.05)。术后1周,两组躯体功能、精神状况、社会功能与总体健康评分均高于术前,且观察组高于对照组,差异有统计学意义(P<0.05)。观察组并发症发生率低于对照组,差异有统计学意义(P<0.05)。结论无框架立体定向系统穿刺引流术联合尿激酶注射治疗中等量高血压脑出血患者的临床疗效更优,有助于促进患者术后神经功能、日常生活活动能力恢复,可有效提升患者术后生命质量,降低减少手术相关并发症的发生风险,具有较高的临床应用价值。
Objective To analyze the efficacy of different puncture and drainage methods combined with urokinase injection in the treatment of moderate hypertensive intracerebral hemorrhage.Methods The clinical data of 100 patients with moderate hypertensive intracerebral hemorrhage admitted to Jinjiang Traditional Chinese Medicine Hospital from January 2020 to October 2023 were retrospectively analyzed,among them,50 patients who underwent CT-guided craniotomy puncture and drainage were assigned to the control group,and 50 patients who underwent frameless stereotactic puncture and drainage were assigned to the observation group.The National Institutes of Health stroke scale(NIHSS)score,activity of daily living(ADL)score,clinical efficacy,36-item short form health survey(SF-36)score and complication rate were compared between the two groups.Results 1 week after operation,the NIHSS scores of the two groups were lower than those before operation,and the ADL scores were higher than those before the operation,the NIHSS score in the observation group was lower than that in the control group,and the ADL score was higher than that in the control group,the differences were statistically significant(P<0.05).The total effective rate of treatment in the observation group was 92.00%,which was higher than 76.00%in the control group,the difference was statistically significant(P<0.05).1 week after operation,the physical function,mental status,social function and overall health scores of the two groups were higher than those before the operation,and the observation group was higher than the control group,the differences were statistically significant(P<0.05).The complication rate in the observation group was lower than that in the control group,the difference was statistically significant(P<0.05).Conclusion Frameless stereotactic puncture and drainage combined with urokinase injection in the treatment of moderate hypertensive intracerebral hemorrhage has excellent clinical efficacy,which is helpful to promote the recovery of postoperative neurological function and activities of daily living,has stable efficacy,can effectively improve the quality of life after surgery,and reduce the risk of surgery-related complications,it has high clinical application value.
作者
许东青
马轶杰
洪朝灿
颜长护
XU Dongqing;MA Yijie;HONG Chaocan;YAN Changhu(Department of Neurosurgery,Jinjiang Traditional Chinese Medicine Hospital,Quanzhou,Fujian,362200,China)
出处
《当代医学》
2025年第4期117-121,共5页
Contemporary Medicine
关键词
CT定位锥颅血肿穿刺引流术
无框架立体定向
尿激酶注射
中等量高血压脑出血
CT-guided craniotomy puncture and drainage
Frameless stereotactic puncture and drainage
Urokinase injection
Moderate hypertensive intracerebral hemorrhage
