Introduction: Pain is a complex phenomenon and in many diseases is the cardinal manifestation. In many of them, the source of pain is obscure and in turn curing pain also becomes difficult. Finding a new regulatory me...Introduction: Pain is a complex phenomenon and in many diseases is the cardinal manifestation. In many of them, the source of pain is obscure and in turn curing pain also becomes difficult. Finding a new regulatory mechanism for pain perception and processing such as alternation of neurogenesis may establish a new treatment. Methods and Materials: In this study, 32 male Sprague-Dawley rats were randomly divided into four groups: social, isolated, morphine-treated socialized (MTS) and morphine-treated isolated (MTI). After injection of BrdU for 14 days (50 mg/kg/rat/day/i.p) and morphine for seven days from day 8 (3 mg/kg/rat/day/i.p), rats were performed tail flick test and then sacrificed. Brains were prepared for assessing neurogenesis and serums were collected for assessing glutathione. Results: In tail flick test isolated and morphine-treated isolated rats had decreased sensitivity to pain stimuli compared to social and morphine-treated socialized rats, respectively. In assessing neurogenesis, isolated and morphine-treated isolated rats had reduced numbers of newly generated neurons compared to social and morphine-treated socialized rats, respectively. Glutathione in serum in isolated and morphine-treated isolated rats increased compared to social and morphine-treated socialized rats, respectively. Conclusion: Reduction of neurogenesis was associated with reduced pain sensitivity in isolated groups. So, isolation may alleviate pain and reduce pain threshold and sensitivity.展开更多
Fruit is one of the essential sources of human nutrition.Consumers around the world need to be able to purchase fruit of reliable flavor and nutritional quality.Physical appearance and physicochemical properties play ...Fruit is one of the essential sources of human nutrition.Consumers around the world need to be able to purchase fruit of reliable flavor and nutritional quality.Physical appearance and physicochemical properties play a key role in determining desirable quality and flavor.However,for some fruits such as watermelon,durian,pineapple,it is very hard to determine quality and flavor by external appearance.Therefore,a practical method to predict physical and physicochemical properties of fruit needs to be developed.In this study,a computerized technique is investigated to determine pineapple grades and their physical and physicochemical properties,including ripeness,total soluble solids,pH value and water content.The results reveal that by grading using pulp characteristics it is possible to classify pineapples into three distinct groups,which are significantly different in TSS,pH value and water content.In addition,predicting pineapple grades using flicking sounds and signal processing demonstrates that pineapples classified as grade 1 and grade 3 are significantly different in TSS,pH value and water content.This suggests that the estimation of the texture of pineapple pulp and its physicochemical properties can be performed prior to cutting.Therefore,it is feasible to develop an automated grading technique that can be used to determine pineapple quality as accurately as destructive grading to predict pineapple grades,texture and physicochemical properties.展开更多
动态电压恢复器(dynamic voltage restorer,DVR)通过注入变压器串联接入电网与负载之间进行电压闪变抑制,其电压输出形成的直流偏磁是导致注入变压器磁饱和问题的关键,也是该类型DVR工程应用的常见难题。为保证DVR稳定运行,减少变压器...动态电压恢复器(dynamic voltage restorer,DVR)通过注入变压器串联接入电网与负载之间进行电压闪变抑制,其电压输出形成的直流偏磁是导致注入变压器磁饱和问题的关键,也是该类型DVR工程应用的常见难题。为保证DVR稳定运行,减少变压器的成本和体积,进行变压器的偏磁抑制十分必要。在分析输出变压器偏磁产生机理的基础上,提出一种利用DVR输出电压积分反馈的偏磁抑制策略,系统的幅频特性分析结果表明,该反馈的引入对原有系统并无影响。利用陷波器对积分反馈环节造成的相位偏移问题进行了补偿校正设计。在Matlab/Simulink中搭建了DVR全系统模型,并开展加入偏磁抑制策略前后的仿真分析。在电压跌落平台进行了120 kVA工业样机验证,试验结果验证了所提方法的有效性。展开更多
文摘Introduction: Pain is a complex phenomenon and in many diseases is the cardinal manifestation. In many of them, the source of pain is obscure and in turn curing pain also becomes difficult. Finding a new regulatory mechanism for pain perception and processing such as alternation of neurogenesis may establish a new treatment. Methods and Materials: In this study, 32 male Sprague-Dawley rats were randomly divided into four groups: social, isolated, morphine-treated socialized (MTS) and morphine-treated isolated (MTI). After injection of BrdU for 14 days (50 mg/kg/rat/day/i.p) and morphine for seven days from day 8 (3 mg/kg/rat/day/i.p), rats were performed tail flick test and then sacrificed. Brains were prepared for assessing neurogenesis and serums were collected for assessing glutathione. Results: In tail flick test isolated and morphine-treated isolated rats had decreased sensitivity to pain stimuli compared to social and morphine-treated socialized rats, respectively. In assessing neurogenesis, isolated and morphine-treated isolated rats had reduced numbers of newly generated neurons compared to social and morphine-treated socialized rats, respectively. Glutathione in serum in isolated and morphine-treated isolated rats increased compared to social and morphine-treated socialized rats, respectively. Conclusion: Reduction of neurogenesis was associated with reduced pain sensitivity in isolated groups. So, isolation may alleviate pain and reduce pain threshold and sensitivity.
文摘Fruit is one of the essential sources of human nutrition.Consumers around the world need to be able to purchase fruit of reliable flavor and nutritional quality.Physical appearance and physicochemical properties play a key role in determining desirable quality and flavor.However,for some fruits such as watermelon,durian,pineapple,it is very hard to determine quality and flavor by external appearance.Therefore,a practical method to predict physical and physicochemical properties of fruit needs to be developed.In this study,a computerized technique is investigated to determine pineapple grades and their physical and physicochemical properties,including ripeness,total soluble solids,pH value and water content.The results reveal that by grading using pulp characteristics it is possible to classify pineapples into three distinct groups,which are significantly different in TSS,pH value and water content.In addition,predicting pineapple grades using flicking sounds and signal processing demonstrates that pineapples classified as grade 1 and grade 3 are significantly different in TSS,pH value and water content.This suggests that the estimation of the texture of pineapple pulp and its physicochemical properties can be performed prior to cutting.Therefore,it is feasible to develop an automated grading technique that can be used to determine pineapple quality as accurately as destructive grading to predict pineapple grades,texture and physicochemical properties.
文摘动态电压恢复器(dynamic voltage restorer,DVR)通过注入变压器串联接入电网与负载之间进行电压闪变抑制,其电压输出形成的直流偏磁是导致注入变压器磁饱和问题的关键,也是该类型DVR工程应用的常见难题。为保证DVR稳定运行,减少变压器的成本和体积,进行变压器的偏磁抑制十分必要。在分析输出变压器偏磁产生机理的基础上,提出一种利用DVR输出电压积分反馈的偏磁抑制策略,系统的幅频特性分析结果表明,该反馈的引入对原有系统并无影响。利用陷波器对积分反馈环节造成的相位偏移问题进行了补偿校正设计。在Matlab/Simulink中搭建了DVR全系统模型,并开展加入偏磁抑制策略前后的仿真分析。在电压跌落平台进行了120 kVA工业样机验证,试验结果验证了所提方法的有效性。
