While the incidence of toddlers’ diabetes is soaring,their mainstay insulins were withdrawn,namely the weak 10% or 20% insulin mixtures (WIM),which were injected only once or twice daily.Consequently,toddlers are coe...While the incidence of toddlers’ diabetes is soaring,their mainstay insulins were withdrawn,namely the weak 10% or 20% insulin mixtures (WIM),which were injected only once or twice daily.Consequently,toddlers are coerced to use an insulin pump,multi-dose insulin regime (MuDIR),mix or dilute insulins.This paper highlights the difficulties and proposes a simple solution.While an insulin pump is the best available option,it is not readily available for everyone.Mixing insulins is not sufficiently precise in small doses.Although diluting insulin would allow precise dosing and reduce the dose variability secondary to dribbling after injections,it,like insulin mixing,deprives children from using the pen and related child-friendly accessories.In MuDIR,we inject 4-5 small doses of insulin instead of 1-2 daily larger doses of WIM.Thus,on using a half unit (unit) insulin pen,a dose of 0.5,1,1.5 and 2 units are adjusted in steps of 100%,50%,33% or 25%;unlike the advisable 5%-20%.This does not easily match the tiny erratic meals of grazing toddlers.Maternal anxiety peaks on watching yo-yoing glycemia.Carers have to accept either persistently high sugar or wild fluctuation.The risks of such poor glycemic pattern are increasingly recognized.Using insulin U20 in a unit disposable pen allows deci-unit dosing,with 5%-20% dose-tuning,greater accuracy on delivering small doses and reduction of dose variability from dribbling.Deci-unit dosing may help avoid wide glycemic swings and provide the affordable alternative to insulin pumps for toddlers.Deci-unit pen materializes the Human Rights of Children,a safer and effective treatment.展开更多
Purpose:This study aims to address the lack of a unified grading framework in Chinese reading by proposing a comprehensive model integrating linguistic complexity and reading experience,to evaluate the difficulty leve...Purpose:This study aims to address the lack of a unified grading framework in Chinese reading by proposing a comprehensive model integrating linguistic complexity and reading experience,to evaluate the difficulty level of Chinese books.Design/methodology/approach:We utilized the Probabilistic Fuzzy Linguistic Technique(PFLT)for subjective indicators related to reading experience.Combined with collected objective indicators data,the Entropy Weight Method(EWM)is used for objective weight allocation,and Tomada De Decisão Interativa Multicritério(TODIM)is applied for multi-criteria decision-making.Findings:The results demonstrate that the proposed framework significantly enhances the alignment between text complexity and reader engagement,achieving a high consistency with authoritative benchmarks.Research limitations:The study may be limited by the scope of subjective and objective indicators used;further validation with more diverse data sources could strengthen generalizability.Practical implications:This approach shows promise in advancing the standardization and objectivity of Chinese reading grading systems,with potential applications in educational and publishing contexts.Originality/value:This study offers a structured evaluation model that incorporates both linguistic complexity and experiential factors,providing a novel and comprehensive method for assessing Chinese text difficulty.展开更多
文摘While the incidence of toddlers’ diabetes is soaring,their mainstay insulins were withdrawn,namely the weak 10% or 20% insulin mixtures (WIM),which were injected only once or twice daily.Consequently,toddlers are coerced to use an insulin pump,multi-dose insulin regime (MuDIR),mix or dilute insulins.This paper highlights the difficulties and proposes a simple solution.While an insulin pump is the best available option,it is not readily available for everyone.Mixing insulins is not sufficiently precise in small doses.Although diluting insulin would allow precise dosing and reduce the dose variability secondary to dribbling after injections,it,like insulin mixing,deprives children from using the pen and related child-friendly accessories.In MuDIR,we inject 4-5 small doses of insulin instead of 1-2 daily larger doses of WIM.Thus,on using a half unit (unit) insulin pen,a dose of 0.5,1,1.5 and 2 units are adjusted in steps of 100%,50%,33% or 25%;unlike the advisable 5%-20%.This does not easily match the tiny erratic meals of grazing toddlers.Maternal anxiety peaks on watching yo-yoing glycemia.Carers have to accept either persistently high sugar or wild fluctuation.The risks of such poor glycemic pattern are increasingly recognized.Using insulin U20 in a unit disposable pen allows deci-unit dosing,with 5%-20% dose-tuning,greater accuracy on delivering small doses and reduction of dose variability from dribbling.Deci-unit dosing may help avoid wide glycemic swings and provide the affordable alternative to insulin pumps for toddlers.Deci-unit pen materializes the Human Rights of Children,a safer and effective treatment.
基金supported by the Humanities and Social Sciences Cultivation Fund Project of the USST(Grant No.24SKPY04)the China Youth and Children Research Association(Grant No.2023B18).
文摘Purpose:This study aims to address the lack of a unified grading framework in Chinese reading by proposing a comprehensive model integrating linguistic complexity and reading experience,to evaluate the difficulty level of Chinese books.Design/methodology/approach:We utilized the Probabilistic Fuzzy Linguistic Technique(PFLT)for subjective indicators related to reading experience.Combined with collected objective indicators data,the Entropy Weight Method(EWM)is used for objective weight allocation,and Tomada De Decisão Interativa Multicritério(TODIM)is applied for multi-criteria decision-making.Findings:The results demonstrate that the proposed framework significantly enhances the alignment between text complexity and reader engagement,achieving a high consistency with authoritative benchmarks.Research limitations:The study may be limited by the scope of subjective and objective indicators used;further validation with more diverse data sources could strengthen generalizability.Practical implications:This approach shows promise in advancing the standardization and objectivity of Chinese reading grading systems,with potential applications in educational and publishing contexts.Originality/value:This study offers a structured evaluation model that incorporates both linguistic complexity and experiential factors,providing a novel and comprehensive method for assessing Chinese text difficulty.
