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利用PEG实验确定女性巨泌乳素cut-off值及比较分析
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作者 宋胜男 陈陆 +3 位作者 刘雨珩 陈怡菲 翟燕红 曹正 《标记免疫分析与临床》 2025年第6期1233-1236,1289,共5页
目的利用聚乙二醇(PEG)沉淀实验,确定本实验室所应用的中国亚辉龙公司的iFlash-3000型化学发光免疫分析仪及相关配套试剂检测巨泌乳素的cut-off值。方法在2024年8月至2024年9月检测的泌乳素1619例标本中,收集泌乳素升高标本206例,进行PE... 目的利用聚乙二醇(PEG)沉淀实验,确定本实验室所应用的中国亚辉龙公司的iFlash-3000型化学发光免疫分析仪及相关配套试剂检测巨泌乳素的cut-off值。方法在2024年8月至2024年9月检测的泌乳素1619例标本中,收集泌乳素升高标本206例,进行PEG确认实验后进行分析,利用ROC曲线计算出cut-off值。结果本实验室巨泌乳素阳性率为12.73%。根据数据分析,PEG结果可分为3组,其中149例(72.33%)为单体泌乳素组,22例(10.68%)为混合泌乳素组,35例(16.99%)为巨泌乳素组。非单泌乳素组与单泌乳素组Youden指数下,当cut-off值为1086.95mIU/L时,灵敏度为77.1%,特异性为64.9%;非巨泌乳素组与巨泌乳素组Youden指数下,当cut-off值为1154.59mIU/L时,灵敏度为68.4%,特异性为70.5%。结论iFlash-3000型化学发光免疫分析仪及配套试剂检测泌乳素与PEG实验结果呈正相关;利用实验室cut-off值与临床信息相互认知才是判断巨泌乳素血症的有效方式。 展开更多
关键词 泌乳素检测 iFlash-3000 PEG实验 cut-off
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Hydro-microstructural behaviors of zeolite/active carbon amended soil-bentonite cut-off wall
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作者 Yong He Shiyu Li +3 位作者 Zhao Zhang Kaofei Zhu He Wei Keneng Zhang 《Journal of Rock Mechanics and Geotechnical Engineering》 2025年第4期2590-2602,共13页
The soil-bentonite(SB)cut-off wall has been widely considered a vertical barrier to effectively control the migration of pollutants in contaminated sites.Recently,active porous materials have been used as a promising ... The soil-bentonite(SB)cut-off wall has been widely considered a vertical barrier to effectively control the migration of pollutants in contaminated sites.Recently,active porous materials have been used as a promising candidate amendment for mitigating chemical degradation and improving the retardation capacity of the SB cut-off wall.In this study,the silty clay from a typical Cr(VI)contaminated site was selected as the body material of the SB cut-off wall,and zeolite and active carbon were used as the modifiers of the silty clay-bentonite backfills,respectively.The impact of the two modifiers on the engineering properties of the backfills was investigated through a series of slump tests,consolidation tests,hydraulic conductivity tests,and microstructure tests.The experimental results demonstrated that the slump curves closely exhibited a linear relationship between standard slump and moisture content.Meanwhile,bentonite could improve the optimum moisture content of the backfills,while the addition of the two modifiers yielded the opposite outcome.As the bentonite content increased,the compression index of the backfills significantly increased,while the hydraulic conductivity decreased.At a given bentonite content of 5%,the addition of zeolite or active carbon resulted in a reduction in the compression index and initial void ratio,while exhibiting minimal impact on the hydraulic conductivity.Scanning electron microscope(SEM)observations indicated that the silty clay-bentonite backfills became increasingly loose with increasing bentonite content,owing to the filling and expansion of dispersed bentonite layers.The amendment of zeolite or active carbon was able to decrease the backfill volume by promoting the agglomeration of layered bentonite.The findings of this study will be useful for the optimal selection of backfill materials and the performance evaluation of the cut-off wall. 展开更多
关键词 Soil-bentonite(SB)backfill cut-off wall SLUMP Compressibility Hydraulic conductivity
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Reasonable control of cut-off voltage to achieve stable lithium metal anode
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作者 Chengcai Liu Yuanxing Zhang +4 位作者 Yawen Liu Ling Zhang Xuefeng Wang Daobin Mu Borong Wu 《Journal of Energy Chemistry》 2025年第7期961-971,共11页
Uneven lithium deposition leading to lithium dendrite growth severely hampers the application of lithium-metal batteries.Modifying the collector with lithiophilic materials helps improve lithium deposition.For lithoph... Uneven lithium deposition leading to lithium dendrite growth severely hampers the application of lithium-metal batteries.Modifying the collector with lithiophilic materials helps improve lithium deposition.For lithophilic materials to modify the collector,the choice of cut-off voltage is very important.While excessively high cut-off voltages may compromise the stability of the modified layer and consequently disrupt ordered lithium deposition,conventional approaches typically employ lower cut-off voltages(particularly 0.1 V)to maintain modification layer stability.However,the 0.1 V cut-off voltage results in incomplete lithium stripping from the lithiophilic material surface.This phenomenon significantly diminishes the lithiophilic properties of the modified layer and consequently leads to substantial nucleation overpotential.Here,we propose to use a moderate cut-voltage stimulation effect to slow down the interfacial shielding effect of residual lithium metal on lithiophilic materials.By optimizing the cut-off voltage for the Cu@Sb_(2)S_(3)collector,the stability of the modified layer can be preserved while enabling the complete stripping of lithium metal from the surface of the lithophilic material.The asymmetric cell received the highest Coulombic efficiency(CE)when the lithium stripping cut-off voltage was set at 0.5 V relative to 0.1 and 2.0 V.At a current density of 1 mA cm^(-2)and a deposition capacity of1 m A h cm^(-2),the CE remained 98.6% at a cut-off voltage of 0.5 V after 140 cycles in an ether electrolyte without lithium nitrate. 展开更多
关键词 Antimony trisulfide Current collector cut-off voltage Lithium metal batteries
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Face stability analysis of longitudinally inclined shield tunnel considering the effect of tensile strength cut-off and pore water pressure
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作者 HUANG Fu WANG Yong-tao +1 位作者 ZHANG Min YANG Zi-han 《Journal of Central South University》 2025年第3期1080-1098,共19页
Because of actual requirement,shield machine always excavates with an inclined angle in longitudinal direction.Since many previous studies mainly focus on the face stability of the horizontal shield tunnel,the effects... Because of actual requirement,shield machine always excavates with an inclined angle in longitudinal direction.Since many previous studies mainly focus on the face stability of the horizontal shield tunnel,the effects of tensile strength cut-off and pore water pressure on the face stability of the longitudinally inclined shield tunnel are not well investigated.A failure mechanism of a longitudinally inclined shield tunnel face is constructed based on the spatial discretization technique and the tensile strength cut-off criterion is introduced to modify the constructed failure mechanism.The pore water pressure is introduced as an external force into the equation of virtual work and the objective function of the chamber pressure of the shield machine is obtained.Moreover,the critical chamber pressure of the longitudinally inclined shield tunnel is computed by optimal calculation.Parametric analysis indicates that both tensile strength cut-off and pore water pressure have a significant impact on the chamber pressure and the range of the collapse block.Finally,the theoretical results are compared with the numerical results calculated by FLAC3D software which proves that the proposed approach is effective. 展开更多
关键词 longitudinally inclined tunnel pore water pressure tensile strength cut-off spatial discretization technique limit analysis
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受试者工作特征曲线在选取肺癌肿瘤标志物cut-off值中的应用
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作者 章玫红 邵普秀 《医学理论与实践》 2025年第10期1737-1739,共3页
目的:分析受试者工作特征(ROC)曲线在选取肺癌肿瘤标志物实验室cut-off值中的临床应用价值。方法:选取我院2021年1月—2023年12月收治的172例经临床病理首次诊断为肺癌患者作为观察组,同期选取172例健康体检人员作为对照组。对纳入对象... 目的:分析受试者工作特征(ROC)曲线在选取肺癌肿瘤标志物实验室cut-off值中的临床应用价值。方法:选取我院2021年1月—2023年12月收治的172例经临床病理首次诊断为肺癌患者作为观察组,同期选取172例健康体检人员作为对照组。对纳入对象的血清胃泌素释放肽前体(pro-GRP)、细胞角蛋白19片段抗原(CYFRA21-1)、神经元特异性烯醇化酶(NSE)和鳞状上皮细胞癌抗原(SCC)检测结果进行统计分析。利用ROC曲线对pro-GRP、CYFRA21-1、NSE、SCC指标辅助诊断肺癌的效能进行分析并选取最优cut-off值;对比分析观察指标说明书标准与ROC曲线选取的cut-off值辅助诊断肺癌的效能差异。结果:CYFRA21-1(AUC:0.803,95%CI:0.745~0.860)对肺腺癌的诊断效能最好,最优cut-off值为2.79ng/mL;SCC(AUC:0.862,95%CI:0.809~0.914)对肺鳞癌的诊断效能最好,最优cut-off值为1.18ng/mL;pro-GRP、CYFRA21-1和SCC三项指标ROC曲线选取的最优cut-off值辅助诊断肺癌的灵敏度、准确度均优于说明书参考标准,差异具有统计学意义(P<0.05)。结论:利用ROC曲线选取实验室的最优cut-off值可提高肺癌肿瘤标志物的诊断效能,有利于对肺癌高危人群的筛查和早期辅助诊断。 展开更多
关键词 受试者工作特征曲线 肺癌肿瘤标志物 最优cut-off 应用价值
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MHz cut-off frequency and permeability mechanism of iron-based soft magnetic composites 被引量:1
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作者 Xiao-Wei Jin Tong Li +1 位作者 Hui-Gang Shi De-Sheng Xue 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第9期560-564,共5页
The lack of soft magnetic composites with high power density in MHz frequency range has become an obstacle in the efficient operation of the electrical and electronic equipments.Here,a promising method to increase the... The lack of soft magnetic composites with high power density in MHz frequency range has become an obstacle in the efficient operation of the electrical and electronic equipments.Here,a promising method to increase the cut-off frequency of iron-based soft magnetic composites to hundreds of MHz is reported.The cut-off frequency is increased from 10 MHz to 1 GHz by modulating the height of the ring,the distribution of particles,and the particle size.The mechanism of cut-off frequency and permeability is the coherent rotation of domain modulated by inhomogeneous field due to the eddy current effect.An empirical formula for the cut-off frequency in a magnetic ring composed of iron-based particles is established from experimental data.This work provides an effective approach to fabricate soft magnetic composites with a cut-off frequency in hundreds of MHz. 展开更多
关键词 cut-off frequency PERMEABILITY eddy current effect soft magnetic composites
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Cut-off value of glycated hemoglobin A1c for detecting diabetic retinopathy in the Chinese population
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作者 Yan Wen Qing Wang 《World Journal of Diabetes》 SCIE 2024年第7期1531-1536,共6页
BACKGROUND Glycated hemoglobin A1c(HbA1c)is considered the most suitable for diabetes mellitus diagnosis due to its accuracy and convenience.However,the effect of HbA1c on diabetic retinopathy(DR)in the Han and Korean... BACKGROUND Glycated hemoglobin A1c(HbA1c)is considered the most suitable for diabetes mellitus diagnosis due to its accuracy and convenience.However,the effect of HbA1c on diabetic retinopathy(DR)in the Han and Korean populations in Jilin,China,remains inconclusive.AIM To determine the best cut-off of HbA1c for diagnosing DR among the Chinese.METHODS This cross-sectional study included 1933 participants from the Yanbian area of Jilin Province,China.Trained investigators employed a questionnaire-based survey,physical examination,laboratory tests,and fundus photography for the investigation.The best cut-off value for HbA1c was established via the receiver operating characteristic curve.The factors associated with HbA1c-associated risk factors were determined via linear regression.RESULTS The analysis included 887 eligible Chinese Han and Korean participants,591 of whom were assigned randomly to the training set and 296 to the validation set.The prevalence of DR was 3.27% in the total population.HbA1c of 6.2% was the best cut-off value in the training set,while it was 5.9% in the validation set.In both Chinese Han and Korean populations,an HbA1c level of 6.2% was the best cut-off value.The optimal cut-off values of fasting blood glucose(FBG)≥7 mmol/L and<7 mmol/L were 8.1% and 6.2% respectively in Han populations,while those in Korean populations were 6.9%and 5.3%,respectively.Age,body mass index,and FBG were determined as the risk factors impacting HbA1c levels.CONCLUSION HbA1c may serve as a useful diagnostic indicator for DR.An HbA1c level of 6.2% may be an appropriate cut-off value for DR detection in the Chinese population. 展开更多
关键词 Diabetic retinopathy Glycated hemoglobin A1c cut-off value Age Body mass index Fasting blood glucose
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ROC曲线确立血液学各指标在地贫筛查中的CUT-OFF值 被引量:10
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作者 张强 何升 +1 位作者 阙婷 唐燕青 《中国优生与遗传杂志》 2013年第1期27-27,25,共2页
目的用ROC曲线(受试者工作特征曲线)确立各血液学指标在地贫筛查中的切值。方法以SYSMEX五分类血细胞分析仪进行全血细胞计数,记录RBC,HB,MCH,MCV,RDW-CV的数值。用伯乐HPLC进行血红蛋白电泳分析记录HBA2值。所有标本进行地中海贫血基... 目的用ROC曲线(受试者工作特征曲线)确立各血液学指标在地贫筛查中的切值。方法以SYSMEX五分类血细胞分析仪进行全血细胞计数,记录RBC,HB,MCH,MCV,RDW-CV的数值。用伯乐HPLC进行血红蛋白电泳分析记录HBA2值。所有标本进行地中海贫血基因检测。采用gap-pcr及RDB(反向点杂交)原理对筛查结果进行验证。结果在地贫筛查中MCV和MCH比较有价值,MCV的价值略大于MCH,RDW-CV,和HBA2对β地贫的筛查价值更加的显著,而RBC及HB在地贫筛查中价值不大。结论为减少漏诊及误诊。 展开更多
关键词 ROC cut-off 地中海贫血 血液学指标
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基于cut-off方法刚性承台下群桩基础优化分析 被引量:2
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作者 梁发云 陈海兵 《岩土力学》 EI CAS CSCD 北大核心 2011年第S1期61-65,共5页
针对刚性筏板下群桩基础优化设计问题进行分析,通过改变桩长分布来调整各桩的荷载分担,群桩分析采用基于弹性理论的积分方程方法,并通过cut-off方法来反映桩的弹塑性特性,实现群桩基础的弹塑性优化分析,改进了常规弹性分析方法的缺陷。... 针对刚性筏板下群桩基础优化设计问题进行分析,通过改变桩长分布来调整各桩的荷载分担,群桩分析采用基于弹性理论的积分方程方法,并通过cut-off方法来反映桩的弹塑性特性,实现群桩基础的弹塑性优化分析,改进了常规弹性分析方法的缺陷。算例分析表明,随着外荷载的不断增加,角桩首先达到极限荷载,对角桩超出极限荷载的部分进行重新分布,继而使得边桩逐渐达到极限承载状态,继续加载直至内桩也达到极限承载状态,从而引起桩筏基础的整体破坏。采用cut-off方法可以改进基础变刚度优化设计,使之与实际情况更为吻合。 展开更多
关键词 cut-off方法 长短桩 优化分析 刚性承台 弹塑性
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利用RIBA试验确定HCV抗体检测的cut-off值及比较分析 被引量:1
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作者 陈陆 徐东 +4 位作者 宋玉杰 石磊 李英 曹正 翟燕红 《标记免疫分析与临床》 CAS 2022年第9期1465-1468,共4页
目的利用重组蛋白免疫印迹分析(RIBA)实验,制定本实验室所用的日本希森美康公司的HISCL-5000型化学发光免疫分析仪及配套的相关试剂检测丙型肝炎病毒抗体(抗-HCV)的cut-off值。方法在2015年10月至2016年9月所检测的19341例患者标本中收... 目的利用重组蛋白免疫印迹分析(RIBA)实验,制定本实验室所用的日本希森美康公司的HISCL-5000型化学发光免疫分析仪及配套的相关试剂检测丙型肝炎病毒抗体(抗-HCV)的cut-off值。方法在2015年10月至2016年9月所检测的19341例患者标本中收集抗-HCV阳性标本80例,进行RIBA确认实验后进行分析,再利用ROC曲线计算出cut-off值。结果在本室HCV抗体阳性率为0.41%的数据中,RIBA结果可分为3种,其中25例(31.3%)为阴性,18例(22.5%)为不确定,37例(46.2%)为阳性。当截断值为3.95 COI时,灵敏度为81.1%,特异性为95.1%。另外当特异性为100%时,截断值为5.25 COI,灵敏度为73%。结论希森美康HISCL-5000型化学发光免疫分析仪及配套的相关试剂检测丙型肝炎病毒抗体(抗-HCV)与RIBA结果间呈正相关;当cut-off值为3.95 COI时,是一个适合本实验室的cut-off值。 展开更多
关键词 HCV抗体检测 希森美康HISCL-5000 RIBA试验 cut-off
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聚乙二醇沉淀巨泌乳素法筛查回收率cut-off值及其灰区设置探讨 被引量:1
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作者 王燕 李思萍 +3 位作者 朱泽华 汪明星 陈兆军 张腊红 《中国卫生检验杂志》 CAS 2022年第6期690-693,698,共5页
目的探讨用聚乙二醇(PEG)沉淀法对高泌乳素血症(HPRL)患者进行巨泌乳素(M-PRL)筛查时,单体泌乳素(PRL)回收率cut-off值及其灰区设置的必要性。方法用PEG沉淀法对1799例HPRL患者进行M-PRL筛查,设定单体PRL回收率40%作为cut-off值,以其上... 目的探讨用聚乙二醇(PEG)沉淀法对高泌乳素血症(HPRL)患者进行巨泌乳素(M-PRL)筛查时,单体泌乳素(PRL)回收率cut-off值及其灰区设置的必要性。方法用PEG沉淀法对1799例HPRL患者进行M-PRL筛查,设定单体PRL回收率40%作为cut-off值,以其上下20%作为灰区,将其分为3组:巨泌乳素组、灰区组和真性HPRL组;同时对3组患者的性激素水平进行检测;结合灰区组患者的临床诊断结果进行分析。结果HPRL患者中,3组人群均以女性为主;性激素项目检测中发现3组患者性激素项目均已出现异常,特别是女性E2、LH/FSH比值在3组患者逐渐增高(P<0.05);灰区组虽高达9.73%,但结合患者的临床诊断结果分析,该组患者主要见于其他疾病,真正HPRL患者不多。结论PEG沉淀法进行M-PRL筛查时单体PRL回收率的灰区设置是有必要的,并且对灰区患者的性激素项目做进一步分析可以帮助临床医生做出更加准确的诊断结果。 展开更多
关键词 聚乙二醇沉淀法 高泌乳素血症 巨泌乳素 cut-off 灰区 性激素
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应用GSP筛查新生儿G6PDd的性能验证及cut-off值设定 被引量:2
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作者 魏庆玲 梁睿 +3 位作者 李冬秀 陈伟荣 吴学威 黄湘 《检验医学与临床》 CAS 2022年第14期1926-1929,共4页
目的对全自动荧光免疫分析仪(GSP)检测干血片葡萄糖-6-磷酸脱氢酶(G6PD)的性能进行验证,并初步建立该方法筛查葡萄糖-6-磷酸脱氢酶缺乏症(G6PDd)的cut-off值。方法前期确定验证方案,对试剂盒自带标准品B、D、E 3个浓度的标本,L、H两个... 目的对全自动荧光免疫分析仪(GSP)检测干血片葡萄糖-6-磷酸脱氢酶(G6PD)的性能进行验证,并初步建立该方法筛查葡萄糖-6-磷酸脱氢酶缺乏症(G6PDd)的cut-off值。方法前期确定验证方案,对试剂盒自带标准品B、D、E 3个浓度的标本,L、H两个浓度的质控品及试剂盒自带标准品B、C、D、E、F 5个浓度标本进行GSP系统的精密度、正确度和线性范围的验证。采用GSP和目前临床常规使用的Victor2D 1420型荧光免疫分析仪(半自动荧光免疫分析仪)同步检测2742例新生儿干血片G6PD水平,比较两种仪器结果,并使用百分位数分布及受试者工作特征(ROC)曲线初步建立中山市博爱医院产前诊断中心GSP筛查G6PDd时G6PD水平的cut-off值。结果应用GSP检测G6PD时,批内变异系数分别为2.09%、1.54%和1.90%,总变异系数分别为3.08%、1.72%和2.12%,分别小于厂家声明的3.40%和3.90%;质控浓度L的25份标本的测量总均值与靶值的相对偏差为3.84%,质控浓度H的25份标本的测量总均值与靶值的相对偏差为3.44%;5个浓度标本的检测值和理论值的线性回归方程为Y=1.0082 X+0.0125,决定系数(R^(2))为0.9991,R^(2)>0.995,线性相关性良好。标本总体P_(5)的G6PD水平为20.10 U/dL。两种仪器的一致性良好。结论GSP应用于中山市新生儿G6PD检测中,精密度、准确度、线性范围均达到了厂家声明的检测性能,可常规用于新生儿G6PDd筛查。该中心初步采用的GSP新生儿G6PDd筛查的cut-off值为20.10 U/dL。 展开更多
关键词 葡萄糖-6-磷酸脱氢酶缺乏症 全自动荧光免疫分析仪 性能验证 cut-off
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Numerical stress-deformation analysis of cut-off wall in clay-core rockfill dam on thick overburden 被引量:12
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作者 Si-hong Liu Liu-jiang Wang +1 位作者 Zi-jian Wang Erich Bauer 《Water Science and Engineering》 EI CAS CSCD 2016年第3期219-226,共8页
The cut-off wall in a clay-core rockfill dam built on a thick overburden layer is subjected to a large compressive pressure under the action of the loads such as the dead weight of both the dam and the overburden laye... The cut-off wall in a clay-core rockfill dam built on a thick overburden layer is subjected to a large compressive pressure under the action of the loads such as the dead weight of both the dam and the overburden layer, the frictional force induced by the differential settlement between the cut-off wall and surrounding soils, and the water pressure. Thus, reduction of the stress of the cut-off wall has become one of the main problems for consideration in engineering design. In this paper, numerical analysis of a core rockfill dam built on a thick overburden layer was conducted and some factors influencing the stress-strain behaviors of the cut-off wall were investigated. The factors include the improvement of the overburden layer, the modeling approach for interfacial contact between the cut-off wall and surrounding soils, the modulus of the cut-off wall concrete, and the connected pattern between the cut-off wall and the clay core. The result shows that improving the overburden layer,selecting plastic concrete with a low modulus and high strength, and optimizing the connection between the cut-off wall and the clay core of the dam are effective measures of reducing the deformations and compressive stresses of the cut-off wall. In addition, both the Goodman element and the mud-layer element are suitable for simulating the interfacial contact between the cut-off wall and surrounding soils. 展开更多
关键词 OVERBURDEN layer Core ROCKFILL DAM cut-off wall NUMERICAL ANALYSIS Stress and deformation ANALYSIS
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A case study of a Kuroshio main path cut-off event and impacts on the South China Sea in fall-winter 2013–2014 被引量:6
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作者 Quanan Zheng Chung-Ru Ho +1 位作者 Lingling Xie Mingming Li 《Acta Oceanologica Sinica》 SCIE CAS CSCD 2019年第4期12-19,共8页
This study examines a Kuroshio main path(KMP) cut-off event east of Taiwan Island occurred in fall-winter2013–2014 and its impacts on the South China Sea(SCS) by analyzing satellite altimetry and mooring observations... This study examines a Kuroshio main path(KMP) cut-off event east of Taiwan Island occurred in fall-winter2013–2014 and its impacts on the South China Sea(SCS) by analyzing satellite altimetry and mooring observations. Satellite altimeter sea level anomaly(SLA) images reveal a complete process that a huge cyclonic eddy(CE) from the Pacific collided with the Kuroshio and the western boundary from 15 October 2013 to 15 January 2014. Mooring observations evidenced that the Kuroshio upper ocean volume transport was cut off more than 82% from 17×106 m^3/s in September to 3×106 m^3/s in November 2013. The KMP cut-off event caused the Kuroshio branching and intruding into the SCS and strengthened the eddy kinetic energy in the northern SCS west of the Luzon Strait. Using the total momentum as a dynamic criterion to determine the role of eddy collision with the Kuroshio reasonably explains the KMP cut-off event. 展开更多
关键词 KMP cut-off EVENT EDDY kinetic energy dynamic criterion South China Sea
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Dynamic monitoring of menopause hormone therapy and defining the cut-off value of endometrial thickness during uterine bleeding 被引量:3
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作者 Qiu Sheng Jun Yang +1 位作者 Qiaoling Zhao Fen Li 《The Journal of Biomedical Research》 CAS CSCD 2016年第3期191-196,共6页
The aim of this study was to evaluate the effects of low-dose tibolone therapy on ovarian area, uterine volume and endometrial thickness, and define the cut-off value of endometrial thickness for curettage during uter... The aim of this study was to evaluate the effects of low-dose tibolone therapy on ovarian area, uterine volume and endometrial thickness, and define the cut-off value of endometrial thickness for curettage during uterine bleeding. We followed 619 postmenopausal women, aged 40-60 years, for two years. There were 301 subjects in the low-dose tibolone treatment group and 318 subjects in the control group. The ovarian area, uterine volume and endometrial thickness in all participants were measured by transvaginal ultrasound prior to, one and two years post enrollment, respectively. Endometrial specimens were collected from all subjects with abnormal uterine bleeding during the follow-up period. We found that the uterine volume in the treatment group was greater than that in the control group, and the difference was significant (P〈0.05), but there were no significant differences in ovarian area and endometrial thickness between the two groups (P〉0.05). When the cut-off value for endometrial thickness was 7.35 ram, the sensitivity and specificity were 100% and 79.07%, respectively, and 85.71% and 93.02% when 7.55 mm was set as the cut-offduring tibolone therapy. The results indicate that low-dose tibolone therapy may postpone uterine atrophy and the cut-off value of endometrial thickness may be appropriately adjusted for curettage. 展开更多
关键词 low-dose tibolone ovarian area uterine volume ENDOMETRIUM dynamic monitoring cut-off value
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The Impact of Cut-off Lows on Ozone in the Upper Troposphere and Lower Stratosphere over Changchun from Ozonesonde Observations 被引量:2
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作者 Yushan SONG Daren LU +3 位作者 Qian LI Jianchun BIAN Xue WU Dan LI 《Advances in Atmospheric Sciences》 SCIE CAS CSCD 2016年第2期135-150,共16页
In situ measurements of the vertical structure of ozone were made in Changchun (43.53°N, 125.13°E), China, by the Institute of Atmosphere Physics, in the summers of 2010-13. Analysis of the 89 validated oz... In situ measurements of the vertical structure of ozone were made in Changchun (43.53°N, 125.13°E), China, by the Institute of Atmosphere Physics, in the summers of 2010-13. Analysis of the 89 validated ozone profiles shows the vari- ation of ozone concentration in the upper troposphere and lower stratosphere (UTLS) caused by cut-off lows (COLs) over Changchun. During the COL events, an increase of the ozone concentration and a lower height of the tropopause are observed. Backward simulations with a trajectory model show that the ozone-rich airmass brought by the COL is from Siberia. A case study proves that stratosphere-troposphere exchange (STE) occurs in the COL. The ozone-rich air mass transported from the stratosphere to the troposphere first becomes unstable, then loses its high ozone concentration. This process usually happens during the decay stage of COLs. In order to understand the influence of COLs on the ozone in the UTLS, statistical analysis of the ozone profiles within COLs, and other profiles, are employed. The results indicate that the ozone concentrations of the in-COL profiles are significantly higher than those of the other profiles between ±4 km around the tropopause. The COLs induce an increase in UTLS column ozone by 32% on average. Meanwhile, the COLs depress the lapse-rate tropopause (LRT)/dynamical tropopause height by 1.4/1.7 km and cause the atmosphere above the tropopause to be less stable. The influence of COLs is durable because the increased ozone concentration lasts at least one day after the COL has passed over Changchun. Furthermore, the relative coefficient between LRT height and lower stratosphere (LS) column ozone is -0.62, which implies a positive correlation between COL strength and LS ozone concentration. 展开更多
关键词 OZONESONDE cut-off low upper troposphere lower stratosphere TROPOPAUSE
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Subseasonal Prediction of Early-summer Northeast Asian Cut-off Lows by BCC-CSM2-HR and GloSea5 被引量:3
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作者 Yu NIE Jie WU +4 位作者 Jinqing ZUO Hong-Li REN Adam A.SCAIFE Nick DUNSTONE Steven C.HARDIMAN 《Advances in Atmospheric Sciences》 SCIE CAS CSCD 2023年第11期2127-2134,共8页
Northeast Asian cut-off lows are crucial cyclonic systems that can bring temperature and precipitation extremes over large areas.Skillful subseasonal forecasting of Northeast Asian cut-off lows is of great importance.... Northeast Asian cut-off lows are crucial cyclonic systems that can bring temperature and precipitation extremes over large areas.Skillful subseasonal forecasting of Northeast Asian cut-off lows is of great importance.Using two dynamical forecasting systems,one from the Beijing Climate Center(BCC-CSM2-HR)and the other from the Met Office(GloSea5),this study assesses simulation ability and subseasonal prediction skill for early-summer Northeast Asian cut-off lows.Both models are shown to have good ability in representing the spatial structure of cut-off lows,but they underestimate the intensity.The skillful prediction time scales for cut-off low intensity are about 10.2 days for BCC-CSM2-HR and 11.4 days for GloSea5 in advance.Further examination shows that both models can essentially capture the initial Rossby wave train,rapid growth and decay processes responsible for the evolution of cut-off lows,but the models show weaker amplitudes for the three-stage processes.The underestimated simulated strength of both the Eurasian midlatitude and East Asian subtropical jets may lead to the weaker local eddy-mean flow interaction responsible for the cut-off low evolution. 展开更多
关键词 Northeast Asia cut-off lows subseasonal prediction skill jet stream
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Effect of copper slag recovery on hydrometallurgical cut-off grades considering environmental aspects 被引量:2
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作者 AFSHIN AKBARI ESMAEIL RAHIMI 《Journal of Central South University》 SCIE EI CAS CSCD 2016年第4期798-807,共10页
Determining the hydrometallurgical cut-off grades specifies the destination of low grade materials and this is subjected to more benefits in mining. Copper production rate is considered as one of the fundamental issue... Determining the hydrometallurgical cut-off grades specifies the destination of low grade materials and this is subjected to more benefits in mining. Copper production rate is considered as one of the fundamental issues in hydrometallurgical cut-off grades determination. Slags are remarked as one of the main sources of copper. It is not only regarded as a waste but also identified as another resource extracting base metals. Slags are characterized by copper high grade. Thus, slag copper recovery can be led to different cut-off grades and net present value(NPV). The current research scrutinizes the effect of slag recovery by both flotation and hydrometallurgical methods on the hydrometallurgical cut-off grades. For this purpose, the optimum cut-off grade algorithms of hydrometallurgical methods are developed by considering associated environmental parameters, incomes and also the costs. Then, their optimum amounts are calculated with NPV maximization as an objective function. The results indicate that considering slag copper recovery in the hydrometallurgical cut-off grade algorithms reduces the environmental costs caused by slag dumping and leads to more NPV by 9%. 展开更多
关键词 HYDROMETALLURGY cut-off grades low grade materials WASTE floatation SLAG copper recovery environmental parameters slag dumping NPV maximization
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Multifractal estimation of NMR T_(2) cut-off value in low-permeability rocks considering spectrum kurtosis: SMOTE-based oversampling integrated with machine learning 被引量:2
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作者 Xiao-Jun Chen Rui-Xue Zhang +4 位作者 Xiao-Bo Zhao Jun-Wei Yang Zhang-Jian Lan Cheng-Fei Luo Jian-Chao Cai 《Petroleum Science》 SCIE EI CAS CSCD 2023年第6期3411-3427,共17页
The transverse relaxation time (T_(2)) cut-off value plays a crucial role in nuclear magnetic resonance for identifying movable and immovable boundaries, evaluating permeability, and determining fluid saturation in pe... The transverse relaxation time (T_(2)) cut-off value plays a crucial role in nuclear magnetic resonance for identifying movable and immovable boundaries, evaluating permeability, and determining fluid saturation in petrophysical characterization of petroleum reservoirs. This study focuses on the systematic analysis of T_(2) spectra and T_(2) cut-off values in low-permeability reservoir rocks. Analysis of 36 low-permeability cores revealed a wide distribution of T_(2) cut-off values, ranging from 7 to 50 ms. Additionally, the T_(2) spectra exhibited multimodal characteristics, predominantly displaying unimodal and bimodal morphologies, with a few trimodal morphologies, which are inherently influenced by different pore types. Fractal characteristics of pore structure in fully water-saturated cores were captured through the T_(2) spectra, which were calculated using generalized fractal and multifractal theories. To augment the limited dataset of 36 cores, the synthetic minority oversampling technique was employed. Models for evaluating the T_(2) cut-off value were separately developed based on the classified T_(2) spectra, considering the number of peaks, and utilizing generalized fractal dimensions at the weight <0 and the singular intensity range. The underlying mechanism is that the singular intensity and generalized fractal dimensions at the weight <0 can detect the T_(2) spectral shift. However, the T_(2) spectral shift has negligible effects on multifractal spectrum function difference and generalized fractal dimensions at the weight >0. The primary objective of this work is to gain insights into the relationship between the kurtosis of the T_(2) spectrum and pore types, as well as to predict the T_(2) cut-off value of low-permeability rocks using machine learning and data augmentation techniques. 展开更多
关键词 Nuclear magnetic resonance Low-permeability porous media T_(2)cut-off value Fractal and multifractal Data augmentation Machine learning
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Collector optimization for tradeoff between breakdown voltage and cut-off frequency in SiGe HBT 被引量:1
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作者 付强 张万荣 +3 位作者 金冬月 丁春宝 赵彦晓 鲁东 《Chinese Physics B》 SCIE EI CAS CSCD 2014年第11期354-358,共5页
As is well known, there exists a tradeoff between the breakdown voltage BVcEO and the cut-off frequency fT for a standard heterojunction bipolar transistor (HBT). In this paper, this tradeoff is alleviated by collec... As is well known, there exists a tradeoff between the breakdown voltage BVcEO and the cut-off frequency fT for a standard heterojunction bipolar transistor (HBT). In this paper, this tradeoff is alleviated by collector doping engineering in the SiGe HBT by utilizing a novel composite of P+ and N- doping layers inside the collector-base (CB) space-charge region (SCR). Compared with the single N-type collector, the introduction of the thin P+ layers provides a reverse electric field weakening the electric field near the CB metallurgical junction without changing the field direction, and the thin N layer further effectively lowers the electric field near the CB metallurgical junction. As a result, the electron temperature near the CB metallurgical junction is lowered, consequently suppressing the impact ionization, thus BVcEO is improved with a slight degradation in fT. The results show that the product of fTXBVcEo is improved from 309.51 GHz.V to 326.35 GHz.V. 展开更多
关键词 SiGe heterojunction bipolar transistors (HBTs) breakdown voltage cut-off frequency collectoroptimization
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