The Kibble-Zurek (KZ) effect offers an overarching description of dynamical scaling behavior near a critical point.[1,2] Originally proposed in a classical setup,the KZ effect has been generalized to quantum phase tra...The Kibble-Zurek (KZ) effect offers an overarching description of dynamical scaling behavior near a critical point.[1,2] Originally proposed in a classical setup,the KZ effect has been generalized to quantum phase transitions[3-5] and is actively explored on quantum simulation platforms.[6-9] Exploring how the KZ effect fares across different criticalities has proven to be a rewarding pursuit,significantly enriching our understanding of nonequilibrium quantum dynamics.[3-5,10-23]展开更多
In this paper,we study the uniqueness of positive solutions to the following semilinear equations{-Δu=λ|x|^(α)ue^(u^(2)),in B_(1),u=0,onδB_(1)ueu2;in B_(1);u=0;on@B_(1);whereλ>0,α>-2;B_(1)denotes the unit ...In this paper,we study the uniqueness of positive solutions to the following semilinear equations{-Δu=λ|x|^(α)ue^(u^(2)),in B_(1),u=0,onδB_(1)ueu2;in B_(1);u=0;on@B_(1);whereλ>0,α>-2;B_(1)denotes the unit disk in R^(2):By delicate and relatively complicated computation of radial solutions to the above equation and the asymptotic expansion of solutions near the boundary of B_(1),the uniqueness of positive solutions is obtained.The results of this paper extend the uniqueness result for the semilinear equation with critical exponential growth in CHEN et al.(2022)to the case that includes a Henon term.展开更多
To ensure the safe transportation of radioactive materials,numerous countries have established specific standards.For the transfer of fissile materials,it is imperative that the material within the packaging remains i...To ensure the safe transportation of radioactive materials,numerous countries have established specific standards.For the transfer of fissile materials,it is imperative that the material within the packaging remains in a subcritical state during routine,normal,and accidental transport conditions.In the event of an accident,the rods within the storage tank may become rearranged,introducing uncertainty that must be accounted for to ensure that criticality analysis results are conservative.Historically,this uncertainty was addressed overly conservatively due to limited research on non-uniform arrangement scenarios,which proved unsuitable for criticality safety analysis of spent fuel packages.This paper introduced three distinct methods to non-uniformly rearrange fuel rods—Uniform Arrangement by Blocks,Layer-by-Layer Determination,and Birdcage Deformation—and meticulously evaluates the influences of rod rearrangement on the effective multiplication factor of neutrons,k eff,utilizing the Monte Carlo method.Ultimately,this study presents a holistic method capable of encompassing the entire spectrum of potential effects stemming from the rearrangement of fuel rods during rods mispositioning accident.By augmenting the safety margin,this approach proves to be adeptly suited for the criticality safety analysis of nuclear fuel transport containers.展开更多
The conventional Kibble–Zurek mechanism,describing driven dynamics across critical points based on the adiabatic-impulse scenario(AIS),has attracted broad attention.However,the driven dynamics at the tricritical poin...The conventional Kibble–Zurek mechanism,describing driven dynamics across critical points based on the adiabatic-impulse scenario(AIS),has attracted broad attention.However,the driven dynamics at the tricritical point with two independent relevant directions have not been adequately studied.Here,we employ the time-dependent variational principle to study the driven critical dynamics at a one-dimensional supersymmetric Ising tricritical point.For the relevant direction along the Ising critical line,the AIS apparently breaks down.Nevertheless,we find that the critical dynamics can still be described by finite-time scaling in which the driving rate has a dimension of r_(μ)=z+1/v_(μ)with z and v_(μ)being the dynamic exponent and correlation length exponent in this direction,respectively.For driven dynamics along another direction,the driving rate has a dimension of r_(p)=z+1/v_(p)with v_(p)being another correlation length exponent.Our work brings a new fundamental perspective into nonequilibrium critical dynamics near the tricritical point,which could be realized in programmable quantum processors in Rydberg atomic systems.展开更多
Rare earths and other critical minerals are widely used in clean energy,semiconductors and other advanced industries,as well as in the defense sector.They are often described as the“gold of the 21st century”and the...Rare earths and other critical minerals are widely used in clean energy,semiconductors and other advanced industries,as well as in the defense sector.They are often described as the“gold of the 21st century”and the“vitamins of industry.”As the United States steps up its containment of China,the Trump administration places great emphasis on critical minerals security.展开更多
BACKGROUND Accurate measurement of energy expenditure(EE)is critical for optimizing nutritional support in critically ill patients.Indirect calorimetry(IC)is the reference method used,but its availability at the bedsi...BACKGROUND Accurate measurement of energy expenditure(EE)is critical for optimizing nutritional support in critically ill patients.Indirect calorimetry(IC)is the reference method used,but its availability at the bedside is limited.As a result,numerous predictive equations have been devised to estimate EE in critically ill patients,along with other more novel methods recently proposed.AIM To evaluate current methods of measuring EE in critical care,focusing on practical challenges,accuracy,feasibility,and limitations.We will also discuss how these methods contribute to improving nutrition support strategies for intensive care unit patients for a more personalised and effective solution.METHODS A comprehensive search was conducted in PubMed and EMBASE for studies published from December 2014 to December 2024.Eligible studies compared EE measurement methods in critically ill populations.Data extraction and quality assessment followed PRISMA guidelines.Adherence to reporting standards was assessed using the TRIPOD questionnaire and risk of bias was evaluated using the PROBAST tool.RESULTS Twenty five original studies met the inclusion criteria and were analysed.CONCLUSION Each method has unique strengths and limitations.We found that while IC remains the reference standard,less accurate predictive equations have greater accessibility and ease of implementation.Emerging technologies show promise for bedside applicability.Future research should address practical barriers and validate newer approaches.展开更多
Amphiphiles,including surfactants,have emerged as indispensable elements in materials science and pharmaceutical science,and their functions are highly relying on the critical micelle concentration(CMC)[1,2].Numerous ...Amphiphiles,including surfactants,have emerged as indispensable elements in materials science and pharmaceutical science,and their functions are highly relying on the critical micelle concentration(CMC)[1,2].Numerous fluorimetry-based probes have been developed to measure CMCs[3](Fig.S1).However,CMC measurements using these probes suffer from a time-consuming and laborious procedure and large uncertainties,primarily due to their poor photo-stabilities and highly fluctuating fluorescence backgrounds.展开更多
This review examines the critical risks,barriers,and success factors in achieving sustainable affordable housing(SAH)by addressing environmental,economic,social and technical dimensions of sustainability.The aim of th...This review examines the critical risks,barriers,and success factors in achieving sustainable affordable housing(SAH)by addressing environmental,economic,social and technical dimensions of sustainability.The aim of this study is to identify different critical risks and barriers to the development of the Sustainable Affordable Housing(SAH)CSF framework.The objectives of this research are to define SAH(Sustainable Affordable Housing)and important factors for achieving SAH and to develop SAH Critical Success Factors(CSFs)frameworks.To achieve these objectives,there are two methods for reviewing and analyzing documents,i.e.,systematic review and bibliographic review.The years of publication are limited to 2014 to 2023 in the English language and restricted to open access.A total of 63 articles were retrieved and screened for relevance identified as directly relevant to our topic using the PRISMA systematic review process.The growth pattern aligns strongly with an exponential growth model,as evidenced by a high R^(2) value of 0.9133 indicating a robust correlation and demonstrating the accelerating interest in the field over the past decade.This comprehensive analysis led to the development of the sustainable affordable housing(SAH)critical success framework,providing a structured approach to understanding and implementing critical factors for sustainable and affordable housing initiatives.The findings emphasize the need for integrated policy reforms,innovative construction technologies,and collaborative stakeholder engagement to advance the SAH agenda.Future research directions include conducting longitudinal studies to assess the long-term impacts of SAH policies,comparative analyses of international best practices,and explorations into emerging construction technologies.展开更多
Deconfined quantum critical points(DQCPs)have been proposed as a class of continuous quantum phase transitions occurring between two ordered phases with distinct symmetry-breaking patterns,beyond the conventional fram...Deconfined quantum critical points(DQCPs)have been proposed as a class of continuous quantum phase transitions occurring between two ordered phases with distinct symmetry-breaking patterns,beyond the conventional framework of Landau-Ginzburg-Wilson(LGW)theory.At the DQCP,the system exhibits emergent gauge fields,fractionalized excitations,and enhanced symmetries.展开更多
Objective:To describe the effects of an early mobilization program in a critically ill patient with acquired muscle weakness in the intensive care unit(AMWICU).Methods:Case report of a 65-year-old male diagnosed with ...Objective:To describe the effects of an early mobilization program in a critically ill patient with acquired muscle weakness in the intensive care unit(AMWICU).Methods:Case report of a 65-year-old male diagnosed with pneumoperitoneum,septic shock,and multiple organ dysfunction.The patient underwent an early mobilization program between 13th and 30th of June 2022,based on expert consensus on safety criteria for mobilization in critically ill patients.The intervention was delivered by a rehabilitation nursing team.Results:The early mobilization program contributed to improvements in muscle strength,body mobility,and functional independence in the critically ill patient.Conclusions:Although there is no consensus on the ideal type,timing,or intensity of early mobilization in critically ill patients,this case study suggests that individualized early mobilization may promote functional recovery and should be considered in intensive care settings.展开更多
The paper is concerned with a class of elliptic equation with critical exponent and Dipole potential.More precisely,we make use of the refined Sobolev inequality with Morrey norm to obtain the existence and decay prop...The paper is concerned with a class of elliptic equation with critical exponent and Dipole potential.More precisely,we make use of the refined Sobolev inequality with Morrey norm to obtain the existence and decay properties of nonnegative radial ground state solutions.展开更多
A much more sustainable,cost effective and very flexible process for manufacturing critical fibres based on ultra high molecular weight polyethylene(UHMWPE)is being launched by the UK’s Fibre Extrusion Technologies(F...A much more sustainable,cost effective and very flexible process for manufacturing critical fibres based on ultra high molecular weight polyethylene(UHMWPE)is being launched by the UK’s Fibre Extrusion Technologies(FET).展开更多
Disordered ferromagnets with a domain structure that exhibit a hysteresis loop when driven by the external magnetic field are essential materials for modern technological applications.Therefore,the understanding and p...Disordered ferromagnets with a domain structure that exhibit a hysteresis loop when driven by the external magnetic field are essential materials for modern technological applications.Therefore,the understanding and potential for controlling the hysteresis phenomenon in thesematerials,especially concerning the disorder-induced critical behavior on the hysteresis loop,have attracted significant experimental,theoretical,and numerical research efforts.We review the challenges of the numerical modeling of physical phenomena behind the hysteresis loop critical behavior in disordered ferromagnetic systems related to the non-equilibriumstochastic dynamics of domain walls driven by external fields.Specifically,using the extended Random Field Ising Model,we present different simulation approaches and advanced numerical techniques that adequately describe the hysteresis loop shapes and the collective nature of the magnetization fluctuations associated with the criticality of the hysteresis loop for different sample shapes and varied parameters of disorder and rate of change of the external field,as well as the influence of thermal fluctuations and demagnetizing fields.The studied examples demonstrate how these numerical approaches reveal newphysical insights,providing quantitativemeasures of pertinent variables extracted from the systems’simulated or experimentally measured Barkhausen noise signals.The described computational techniques using inherent scale-invariance can be applied to the analysis of various complex systems,both quantum and classical,exhibiting non-equilibrium dynamical critical point or self-organized criticality.展开更多
Objective:This study’s purpose is to explore the application of the O-AMAS teaching model combined with the PBL teaching method in the clinical teaching of neurocritical care trainee nurses.Methods:The nursing studen...Objective:This study’s purpose is to explore the application of the O-AMAS teaching model combined with the PBL teaching method in the clinical teaching of neurocritical care trainee nurses.Methods:The nursing students who were doing internship in neurocritical care from June 2024 to September 2024 were set as the control group,and the traditional one-on-one teaching mode was adopted;From October 2024 to January 2025,the nursing students were set as the observation group and the course teaching based on the O-AMAS teaching model combined with PBL teaching was implemented.Results:The theoretical examination scores,operational assessment scores,teaching satisfaction,autonomous learning ability and clinical evaluation thinking ability of the two groups of nursing students were observed.The score of the experimental group was significantly higher than that of the control group(all P<0.01).Conclusion:The application of the O-AMAS teaching model combined with PBL teaching in the clinical teaching of neurocritical care intern nursing students can improve the teaching effect and cultivate the autonomous learning ability and clinical evaluation thinking ability of nursing students.展开更多
BACKGROUND Acute hyperglycemia due to insulin resistance is common in critically ill patients,typically managed with insulin infusion.However,the occurrence of transient extreme insulin resistance(EIR)requiring except...BACKGROUND Acute hyperglycemia due to insulin resistance is common in critically ill patients,typically managed with insulin infusion.However,the occurrence of transient extreme insulin resistance(EIR)requiring exceptional high-dose insulin is rare.CASE SUMMARY We present the case of a 68-year-old woman with pneumonia who suffered an out-of-hospital cardiac arrest,subsequently developing transient EIR following a new episode of sepsis.Remarkably,insulin resistance rapidly reversed when the insulin infusion rate peaked at 960 units/hour(a total of 18224 units on that day),and it was promptly titrated down to zero upon achieving the target glucose level.CONCLUSION Exceptional high-dose insulin infusion may be required in critically ill patients with stress-related EIR,which is typically transient.Clinicians should be aware of the phenomenon and cautious to avoid hypoglycemia and fluid overload during the steep titration of high-dose insulin infusion.展开更多
The advancement of Artificial Intelligence(AI)has garnered significant attention within the academic research community,reflecting the prevailing zeitgeist.However,there is a paucity of literature that has delved into...The advancement of Artificial Intelligence(AI)has garnered significant attention within the academic research community,reflecting the prevailing zeitgeist.However,there is a paucity of literature that has delved into its connection with the higher order thinking skills of human beings.The purpose of this systematic review is to investigate the relationship between AI utilization and the development of critical thinking(CT)in the field of education.A systematic literature search was performed in two databases,Web of Science and Scopus,with a focus on empirical studies related to AI and CT.The review process followed the PRISMA framework and adopted a bottom-up approach,Ultimately,the integrated review synthesized 21 eligible studies from a total of 649 articles.The systematic review identified three relationships between AI technologies and CT.The results suggest that AI technologies can help to enhance learners’CT skills(n=13).However,excessive or inappropriate utilization of AI may hinder CT development(n=7).Moreover,the cultivation of CT skills has been shown to positively influence the effectiveness of AI utilization(n=4).This article represents the first literature review to delve into the reciprocal relationship between AI implementation and CT development within the education field,striving to illuminate the ways in which learners can enhance their higher-order thinking skills through more effective utilization of AI technologies.展开更多
BACKGROUND Empathetic psychological care improves mood and enhances the quality of life in critically ill patients.AIM To study the impact of combining 222-nm ultraviolet(UV)disinfection with empathetic psychological ...BACKGROUND Empathetic psychological care improves mood and enhances the quality of life in critically ill patients.AIM To study the impact of combining 222-nm ultraviolet(UV)disinfection with empathetic psychological care on emotional states,nosocomial infection rates,and quality of life in critically ill patients.METHODS A total of 202 critically ill patients admitted to Beijing Ditan Hospital(December 2023 to May 2024)were randomly assigned to control(Ctrl,n=101)or observation groups(Obs,n=101).The Ctrl group received 222-nm UV disinfection and routine care,while the Obs group received 222-nm UV disinfection with empathetic psychological care.Emotional states[Self-Rating Anxiety Scale(SAS),Self-Rating Depression Scale(SDS)],hospital infection rates,quality of life(36-Item Short Form Health Survey),and patient satisfaction were evaluated.RESULTS At baseline,there were no significant differences in SAS and SDS scores between the groups(P>0.05).Following care,both groups demonstrated reductions in SAS and SDS scores,with the Obs group exhibiting a significantly greater reduction(P<0.05).The Obs group also experienced a significantly lower overall hospital infection rate(P<0.05).Similarly,while baseline 36-Item Short Form Health Survey scores did not differ significantly between the groups(P>0.05),post-care scores improved in both groups,with a greater improvement observed in the Obs group(P<0.05).Additionally,the Obs group reported higher patient satisfaction ratings(P<0.05).CONCLUSION The combination of 222-nm UV disinfection and empathetic psychological care improves emotional states,reduces hospital infection rates,enhances the quality of life,and increases patient satisfaction among critically ill patients.展开更多
Objectives:Nurses working in critical care units may encounter substantial work-related strain,and elevated levels of stress can lead to burnout,ultimately impacting both the quality of nursing care and their overall ...Objectives:Nurses working in critical care units may encounter substantial work-related strain,and elevated levels of stress can lead to burnout,ultimately impacting both the quality of nursing care and their overall working experience.This study aimed to assess job burnout and determine the factors that contribute to it among critical care nurses in the Eastern Province of Saudi Arabia.Methods:This study employed a descriptive,exploratory,cross-sectional research design.A total of 220 nurses employed in the critical care units of 5 private hospitals in the eastern region were selected for participation in this study using a convenience sample method.An electronic survey was distributed to critical care nurses in the Eastern Province who satisfied the specified inclusion criteria.The job burnout questionnaire utilized in this study was derived from previously conducted research,which has been established as a reliable and valid survey instrument.The process of data analysis was conducted utilizing the SPSS program.The scientific research conducted on human subjects adhered rigorously to all ethical considerations.Results:The highest percentage of nurses at the critical care units reported experiencing moderate levels of job burnout.Nurses exhibiting greater levels of professional experience demonstrated a statistically significant reduction in overall burnout scores when compared to their less experienced counterparts.Furthermore,within the realm of sociodemographic factors,it was found that the only significant independent predictor for job burnout was the level of experience among critical care nurses.Conclusions:The prevalence of burnout among nurses in critical care settings was found to be significant,with most participants reporting moderate levels of burnout which can yield significant ramifications for nurses and healthcare professionals.Consequently,healthcare organizations must accord primacy to the welfare of their staff and adopt proactive strategies to mitigate job burnout.展开更多
Management of patients with acute hemorrhage requires addressing the source of bleeding,replenishing blood volume,and addressing any coagulopathy that may be present.Assessing coagulopathy and predicting blood require...Management of patients with acute hemorrhage requires addressing the source of bleeding,replenishing blood volume,and addressing any coagulopathy that may be present.Assessing coagulopathy and predicting blood requirements in real-time in patients experiencing ongoing bleeding can pose substantial challenges.In these patients,transfusion concepts based on ratios do not effectively address coagulopathy or reduce mortality.Moreover,ratio-based concepts do not stop bleeding;instead,they just give physicians more time to identify the bleeding source and plan management strategies.In clinical practice,standard laboratory coagulation tests(SLCT)are frequently used to assess various aspects of blood clotting.However,these tests may not always offer a comprehensive under-standing of clinically significant coagulopathy and the severity of blood loss.Furthermore,the SLCT have a considerable turnaround time,which may not be ideal for making prompt clinical decisions.In recent years,there has been a growing interest in point-of-care viscoelastic assays like rotational thromboelast-ometry,which provide real-time,dynamic information about clot formation and dissolution.展开更多
BACKGROUND Managing critical care emergencies in children with autism spectrum disorder(ASD)presents unique challenges due to their distinct sensory sensitivities,communication difficulties,and behavioral issues.Effec...BACKGROUND Managing critical care emergencies in children with autism spectrum disorder(ASD)presents unique challenges due to their distinct sensory sensitivities,communication difficulties,and behavioral issues.Effective strategies and protocols are essential for optimal care in these high-stress situations.AIM To systematically evaluate and synthesize current evidence on best practices for managing critical care emergencies in children with ASD.The review focuses on key areas,including sensory-friendly environments,communication strategies,behavioral management,and the role of multidisciplinary approaches.METHODS A comprehensive search was conducted across major medical databases,including PubMed,Embase,and Cochrane Library,for studies published between 2000 and 2023.Studies were selected based on their relevance to critical care management in children with ASD,encompassing randomized controlled trials,observational studies,qualitative research,and case studies.Data were extracted and analyzed to identify common themes,successful strategies,and areas for improvement.RESULTS The review identified 50 studies that met the inclusion criteria.Findings highlighted the importance of creating sensory-friendly environments,utilizing effective communication strategies,and implementing individualized behavioral management plans.These findings,derived from a comprehensive review of current evidence,provide valuable insights into the best practices for managing critical care emergencies in children with ASD.Sensory modifications,such as reduced lighting and noise,visual aids,and augmentative and alternative communication tools,enhanced patient comfort and cooperation.The involvement of multidisciplinary teams was crucial in delivering holistic care.Case studies provided practical insights and underscored the need for continuous refi-nement of protocols.CONCLUSION The review emphasizes the need for a tailored approach to managing critical care emergencies for children with ASD.Sensory-friendly adjustments,effective communication,and behavioral strategies supported by a mul-tidisciplinary team are integral to improving outcomes.Despite progress,ongoing refinement of care practices and protocols is necessary.This ongoing process addresses remaining challenges and engages healthcare professionals in continuous improvement of care for children with ASD in critical settings.展开更多
文摘The Kibble-Zurek (KZ) effect offers an overarching description of dynamical scaling behavior near a critical point.[1,2] Originally proposed in a classical setup,the KZ effect has been generalized to quantum phase transitions[3-5] and is actively explored on quantum simulation platforms.[6-9] Exploring how the KZ effect fares across different criticalities has proven to be a rewarding pursuit,significantly enriching our understanding of nonequilibrium quantum dynamics.[3-5,10-23]
基金Supported by the Natural Science Foundation of China(12571122,12061010)。
文摘In this paper,we study the uniqueness of positive solutions to the following semilinear equations{-Δu=λ|x|^(α)ue^(u^(2)),in B_(1),u=0,onδB_(1)ueu2;in B_(1);u=0;on@B_(1);whereλ>0,α>-2;B_(1)denotes the unit disk in R^(2):By delicate and relatively complicated computation of radial solutions to the above equation and the asymptotic expansion of solutions near the boundary of B_(1),the uniqueness of positive solutions is obtained.The results of this paper extend the uniqueness result for the semilinear equation with critical exponential growth in CHEN et al.(2022)to the case that includes a Henon term.
文摘To ensure the safe transportation of radioactive materials,numerous countries have established specific standards.For the transfer of fissile materials,it is imperative that the material within the packaging remains in a subcritical state during routine,normal,and accidental transport conditions.In the event of an accident,the rods within the storage tank may become rearranged,introducing uncertainty that must be accounted for to ensure that criticality analysis results are conservative.Historically,this uncertainty was addressed overly conservatively due to limited research on non-uniform arrangement scenarios,which proved unsuitable for criticality safety analysis of spent fuel packages.This paper introduced three distinct methods to non-uniformly rearrange fuel rods—Uniform Arrangement by Blocks,Layer-by-Layer Determination,and Birdcage Deformation—and meticulously evaluates the influences of rod rearrangement on the effective multiplication factor of neutrons,k eff,utilizing the Monte Carlo method.Ultimately,this study presents a holistic method capable of encompassing the entire spectrum of potential effects stemming from the rearrangement of fuel rods during rods mispositioning accident.By augmenting the safety margin,this approach proves to be adeptly suited for the criticality safety analysis of nuclear fuel transport containers.
基金supported by the National Natural Science Foundation of China(Grant Nos.12222515,12075324 for S.Yin,and 12347107,1257-4160 for Y.F.Jiang)the National Key R&D Program of China(Grant No.2022YFA1402703 for Y.F.Jiang)+1 种基金the Science and Technology Projects in Guangdong Province(Grant No.2021QN02X561 for S.Yin)the Science and Technology Projects in Guangzhou City(Grant No.2025A04J5408 for S.Yin)。
文摘The conventional Kibble–Zurek mechanism,describing driven dynamics across critical points based on the adiabatic-impulse scenario(AIS),has attracted broad attention.However,the driven dynamics at the tricritical point with two independent relevant directions have not been adequately studied.Here,we employ the time-dependent variational principle to study the driven critical dynamics at a one-dimensional supersymmetric Ising tricritical point.For the relevant direction along the Ising critical line,the AIS apparently breaks down.Nevertheless,we find that the critical dynamics can still be described by finite-time scaling in which the driving rate has a dimension of r_(μ)=z+1/v_(μ)with z and v_(μ)being the dynamic exponent and correlation length exponent in this direction,respectively.For driven dynamics along another direction,the driving rate has a dimension of r_(p)=z+1/v_(p)with v_(p)being another correlation length exponent.Our work brings a new fundamental perspective into nonequilibrium critical dynamics near the tricritical point,which could be realized in programmable quantum processors in Rydberg atomic systems.
文摘Rare earths and other critical minerals are widely used in clean energy,semiconductors and other advanced industries,as well as in the defense sector.They are often described as the“gold of the 21st century”and the“vitamins of industry.”As the United States steps up its containment of China,the Trump administration places great emphasis on critical minerals security.
文摘BACKGROUND Accurate measurement of energy expenditure(EE)is critical for optimizing nutritional support in critically ill patients.Indirect calorimetry(IC)is the reference method used,but its availability at the bedside is limited.As a result,numerous predictive equations have been devised to estimate EE in critically ill patients,along with other more novel methods recently proposed.AIM To evaluate current methods of measuring EE in critical care,focusing on practical challenges,accuracy,feasibility,and limitations.We will also discuss how these methods contribute to improving nutrition support strategies for intensive care unit patients for a more personalised and effective solution.METHODS A comprehensive search was conducted in PubMed and EMBASE for studies published from December 2014 to December 2024.Eligible studies compared EE measurement methods in critically ill populations.Data extraction and quality assessment followed PRISMA guidelines.Adherence to reporting standards was assessed using the TRIPOD questionnaire and risk of bias was evaluated using the PROBAST tool.RESULTS Twenty five original studies met the inclusion criteria and were analysed.CONCLUSION Each method has unique strengths and limitations.We found that while IC remains the reference standard,less accurate predictive equations have greater accessibility and ease of implementation.Emerging technologies show promise for bedside applicability.Future research should address practical barriers and validate newer approaches.
基金supported by Shanghai Municipal Commission of Science and Technology,China(Grant No.:19XD1400300)the National Natural Science Foundation of China(Grant Nos.:821040821,82273867,and 82030107).
文摘Amphiphiles,including surfactants,have emerged as indispensable elements in materials science and pharmaceutical science,and their functions are highly relying on the critical micelle concentration(CMC)[1,2].Numerous fluorimetry-based probes have been developed to measure CMCs[3](Fig.S1).However,CMC measurements using these probes suffer from a time-consuming and laborious procedure and large uncertainties,primarily due to their poor photo-stabilities and highly fluctuating fluorescence backgrounds.
文摘This review examines the critical risks,barriers,and success factors in achieving sustainable affordable housing(SAH)by addressing environmental,economic,social and technical dimensions of sustainability.The aim of this study is to identify different critical risks and barriers to the development of the Sustainable Affordable Housing(SAH)CSF framework.The objectives of this research are to define SAH(Sustainable Affordable Housing)and important factors for achieving SAH and to develop SAH Critical Success Factors(CSFs)frameworks.To achieve these objectives,there are two methods for reviewing and analyzing documents,i.e.,systematic review and bibliographic review.The years of publication are limited to 2014 to 2023 in the English language and restricted to open access.A total of 63 articles were retrieved and screened for relevance identified as directly relevant to our topic using the PRISMA systematic review process.The growth pattern aligns strongly with an exponential growth model,as evidenced by a high R^(2) value of 0.9133 indicating a robust correlation and demonstrating the accelerating interest in the field over the past decade.This comprehensive analysis led to the development of the sustainable affordable housing(SAH)critical success framework,providing a structured approach to understanding and implementing critical factors for sustainable and affordable housing initiatives.The findings emphasize the need for integrated policy reforms,innovative construction technologies,and collaborative stakeholder engagement to advance the SAH agenda.Future research directions include conducting longitudinal studies to assess the long-term impacts of SAH policies,comparative analyses of international best practices,and explorations into emerging construction technologies.
基金supported by the National Natural Science Foundation of China(Grant Nos.12134020 and 12374156)the National Key Research and Development Program of China(Grant No.2023YFA1406500)。
文摘Deconfined quantum critical points(DQCPs)have been proposed as a class of continuous quantum phase transitions occurring between two ordered phases with distinct symmetry-breaking patterns,beyond the conventional framework of Landau-Ginzburg-Wilson(LGW)theory.At the DQCP,the system exhibits emergent gauge fields,fractionalized excitations,and enhanced symmetries.
文摘Objective:To describe the effects of an early mobilization program in a critically ill patient with acquired muscle weakness in the intensive care unit(AMWICU).Methods:Case report of a 65-year-old male diagnosed with pneumoperitoneum,septic shock,and multiple organ dysfunction.The patient underwent an early mobilization program between 13th and 30th of June 2022,based on expert consensus on safety criteria for mobilization in critically ill patients.The intervention was delivered by a rehabilitation nursing team.Results:The early mobilization program contributed to improvements in muscle strength,body mobility,and functional independence in the critically ill patient.Conclusions:Although there is no consensus on the ideal type,timing,or intensity of early mobilization in critically ill patients,this case study suggests that individualized early mobilization may promote functional recovery and should be considered in intensive care settings.
基金supported by the Natural Science Research Project of Anhui Educational Committee(2023AH040155)Zhisu Liu's research was supported by the Guangdong Basic and Applied Basic Research Foundation(2023A1515011679+2 种基金2024A1515012704)the Fundamental Research Funds for the Central Universities,China University of Geosciences(Wuhan)(CUG2106211CUGST2).
文摘The paper is concerned with a class of elliptic equation with critical exponent and Dipole potential.More precisely,we make use of the refined Sobolev inequality with Morrey norm to obtain the existence and decay properties of nonnegative radial ground state solutions.
文摘A much more sustainable,cost effective and very flexible process for manufacturing critical fibres based on ultra high molecular weight polyethylene(UHMWPE)is being launched by the UK’s Fibre Extrusion Technologies(FET).
基金Djordje Spasojevic and Svetislav Mijatovic acknowledge the support from the Ministry of Science,TechnologicalDevelopment and Innovation of the Republic of Serbia(Agreement No.451-03-65/2024-03/200162)S.J.ibid.(Agreement No.451-03-65/2024-03/200122)Bosiljka Tadic from the Slovenian Research Agency(program P1-0044).
文摘Disordered ferromagnets with a domain structure that exhibit a hysteresis loop when driven by the external magnetic field are essential materials for modern technological applications.Therefore,the understanding and potential for controlling the hysteresis phenomenon in thesematerials,especially concerning the disorder-induced critical behavior on the hysteresis loop,have attracted significant experimental,theoretical,and numerical research efforts.We review the challenges of the numerical modeling of physical phenomena behind the hysteresis loop critical behavior in disordered ferromagnetic systems related to the non-equilibriumstochastic dynamics of domain walls driven by external fields.Specifically,using the extended Random Field Ising Model,we present different simulation approaches and advanced numerical techniques that adequately describe the hysteresis loop shapes and the collective nature of the magnetization fluctuations associated with the criticality of the hysteresis loop for different sample shapes and varied parameters of disorder and rate of change of the external field,as well as the influence of thermal fluctuations and demagnetizing fields.The studied examples demonstrate how these numerical approaches reveal newphysical insights,providing quantitativemeasures of pertinent variables extracted from the systems’simulated or experimentally measured Barkhausen noise signals.The described computational techniques using inherent scale-invariance can be applied to the analysis of various complex systems,both quantum and classical,exhibiting non-equilibrium dynamical critical point or self-organized criticality.
基金Research and Practice on the Training Model of Clinical Medical Talents in the Context of“New Medicine”at Chengdu Medical College Educational Teaching Reform Project(Project No.:JG2023058)Research and Practice on the Training model of Clinical Medical Talents in the Context of“New Medical Science”(Project No.:JG2023057)。
文摘Objective:This study’s purpose is to explore the application of the O-AMAS teaching model combined with the PBL teaching method in the clinical teaching of neurocritical care trainee nurses.Methods:The nursing students who were doing internship in neurocritical care from June 2024 to September 2024 were set as the control group,and the traditional one-on-one teaching mode was adopted;From October 2024 to January 2025,the nursing students were set as the observation group and the course teaching based on the O-AMAS teaching model combined with PBL teaching was implemented.Results:The theoretical examination scores,operational assessment scores,teaching satisfaction,autonomous learning ability and clinical evaluation thinking ability of the two groups of nursing students were observed.The score of the experimental group was significantly higher than that of the control group(all P<0.01).Conclusion:The application of the O-AMAS teaching model combined with PBL teaching in the clinical teaching of neurocritical care intern nursing students can improve the teaching effect and cultivate the autonomous learning ability and clinical evaluation thinking ability of nursing students.
文摘BACKGROUND Acute hyperglycemia due to insulin resistance is common in critically ill patients,typically managed with insulin infusion.However,the occurrence of transient extreme insulin resistance(EIR)requiring exceptional high-dose insulin is rare.CASE SUMMARY We present the case of a 68-year-old woman with pneumonia who suffered an out-of-hospital cardiac arrest,subsequently developing transient EIR following a new episode of sepsis.Remarkably,insulin resistance rapidly reversed when the insulin infusion rate peaked at 960 units/hour(a total of 18224 units on that day),and it was promptly titrated down to zero upon achieving the target glucose level.CONCLUSION Exceptional high-dose insulin infusion may be required in critically ill patients with stress-related EIR,which is typically transient.Clinicians should be aware of the phenomenon and cautious to avoid hypoglycemia and fluid overload during the steep titration of high-dose insulin infusion.
基金funded by Macao Polytechnic University grant number RP/FCA-08-2023.
文摘The advancement of Artificial Intelligence(AI)has garnered significant attention within the academic research community,reflecting the prevailing zeitgeist.However,there is a paucity of literature that has delved into its connection with the higher order thinking skills of human beings.The purpose of this systematic review is to investigate the relationship between AI utilization and the development of critical thinking(CT)in the field of education.A systematic literature search was performed in two databases,Web of Science and Scopus,with a focus on empirical studies related to AI and CT.The review process followed the PRISMA framework and adopted a bottom-up approach,Ultimately,the integrated review synthesized 21 eligible studies from a total of 649 articles.The systematic review identified three relationships between AI technologies and CT.The results suggest that AI technologies can help to enhance learners’CT skills(n=13).However,excessive or inappropriate utilization of AI may hinder CT development(n=7).Moreover,the cultivation of CT skills has been shown to positively influence the effectiveness of AI utilization(n=4).This article represents the first literature review to delve into the reciprocal relationship between AI implementation and CT development within the education field,striving to illuminate the ways in which learners can enhance their higher-order thinking skills through more effective utilization of AI technologies.
基金Supported by Beijing Ditan Hospital Affiliated to Capital Medical University“Sailing Plan”,No.DTQH-202405.
文摘BACKGROUND Empathetic psychological care improves mood and enhances the quality of life in critically ill patients.AIM To study the impact of combining 222-nm ultraviolet(UV)disinfection with empathetic psychological care on emotional states,nosocomial infection rates,and quality of life in critically ill patients.METHODS A total of 202 critically ill patients admitted to Beijing Ditan Hospital(December 2023 to May 2024)were randomly assigned to control(Ctrl,n=101)or observation groups(Obs,n=101).The Ctrl group received 222-nm UV disinfection and routine care,while the Obs group received 222-nm UV disinfection with empathetic psychological care.Emotional states[Self-Rating Anxiety Scale(SAS),Self-Rating Depression Scale(SDS)],hospital infection rates,quality of life(36-Item Short Form Health Survey),and patient satisfaction were evaluated.RESULTS At baseline,there were no significant differences in SAS and SDS scores between the groups(P>0.05).Following care,both groups demonstrated reductions in SAS and SDS scores,with the Obs group exhibiting a significantly greater reduction(P<0.05).The Obs group also experienced a significantly lower overall hospital infection rate(P<0.05).Similarly,while baseline 36-Item Short Form Health Survey scores did not differ significantly between the groups(P>0.05),post-care scores improved in both groups,with a greater improvement observed in the Obs group(P<0.05).Additionally,the Obs group reported higher patient satisfaction ratings(P<0.05).CONCLUSION The combination of 222-nm UV disinfection and empathetic psychological care improves emotional states,reduces hospital infection rates,enhances the quality of life,and increases patient satisfaction among critically ill patients.
文摘Objectives:Nurses working in critical care units may encounter substantial work-related strain,and elevated levels of stress can lead to burnout,ultimately impacting both the quality of nursing care and their overall working experience.This study aimed to assess job burnout and determine the factors that contribute to it among critical care nurses in the Eastern Province of Saudi Arabia.Methods:This study employed a descriptive,exploratory,cross-sectional research design.A total of 220 nurses employed in the critical care units of 5 private hospitals in the eastern region were selected for participation in this study using a convenience sample method.An electronic survey was distributed to critical care nurses in the Eastern Province who satisfied the specified inclusion criteria.The job burnout questionnaire utilized in this study was derived from previously conducted research,which has been established as a reliable and valid survey instrument.The process of data analysis was conducted utilizing the SPSS program.The scientific research conducted on human subjects adhered rigorously to all ethical considerations.Results:The highest percentage of nurses at the critical care units reported experiencing moderate levels of job burnout.Nurses exhibiting greater levels of professional experience demonstrated a statistically significant reduction in overall burnout scores when compared to their less experienced counterparts.Furthermore,within the realm of sociodemographic factors,it was found that the only significant independent predictor for job burnout was the level of experience among critical care nurses.Conclusions:The prevalence of burnout among nurses in critical care settings was found to be significant,with most participants reporting moderate levels of burnout which can yield significant ramifications for nurses and healthcare professionals.Consequently,healthcare organizations must accord primacy to the welfare of their staff and adopt proactive strategies to mitigate job burnout.
文摘Management of patients with acute hemorrhage requires addressing the source of bleeding,replenishing blood volume,and addressing any coagulopathy that may be present.Assessing coagulopathy and predicting blood requirements in real-time in patients experiencing ongoing bleeding can pose substantial challenges.In these patients,transfusion concepts based on ratios do not effectively address coagulopathy or reduce mortality.Moreover,ratio-based concepts do not stop bleeding;instead,they just give physicians more time to identify the bleeding source and plan management strategies.In clinical practice,standard laboratory coagulation tests(SLCT)are frequently used to assess various aspects of blood clotting.However,these tests may not always offer a comprehensive under-standing of clinically significant coagulopathy and the severity of blood loss.Furthermore,the SLCT have a considerable turnaround time,which may not be ideal for making prompt clinical decisions.In recent years,there has been a growing interest in point-of-care viscoelastic assays like rotational thromboelast-ometry,which provide real-time,dynamic information about clot formation and dissolution.
文摘BACKGROUND Managing critical care emergencies in children with autism spectrum disorder(ASD)presents unique challenges due to their distinct sensory sensitivities,communication difficulties,and behavioral issues.Effective strategies and protocols are essential for optimal care in these high-stress situations.AIM To systematically evaluate and synthesize current evidence on best practices for managing critical care emergencies in children with ASD.The review focuses on key areas,including sensory-friendly environments,communication strategies,behavioral management,and the role of multidisciplinary approaches.METHODS A comprehensive search was conducted across major medical databases,including PubMed,Embase,and Cochrane Library,for studies published between 2000 and 2023.Studies were selected based on their relevance to critical care management in children with ASD,encompassing randomized controlled trials,observational studies,qualitative research,and case studies.Data were extracted and analyzed to identify common themes,successful strategies,and areas for improvement.RESULTS The review identified 50 studies that met the inclusion criteria.Findings highlighted the importance of creating sensory-friendly environments,utilizing effective communication strategies,and implementing individualized behavioral management plans.These findings,derived from a comprehensive review of current evidence,provide valuable insights into the best practices for managing critical care emergencies in children with ASD.Sensory modifications,such as reduced lighting and noise,visual aids,and augmentative and alternative communication tools,enhanced patient comfort and cooperation.The involvement of multidisciplinary teams was crucial in delivering holistic care.Case studies provided practical insights and underscored the need for continuous refi-nement of protocols.CONCLUSION The review emphasizes the need for a tailored approach to managing critical care emergencies for children with ASD.Sensory-friendly adjustments,effective communication,and behavioral strategies supported by a mul-tidisciplinary team are integral to improving outcomes.Despite progress,ongoing refinement of care practices and protocols is necessary.This ongoing process addresses remaining challenges and engages healthcare professionals in continuous improvement of care for children with ASD in critical settings.
