Objective: To analyze the clinical value of cognitive function training combined with daily life ability training in patients with Alzheimer's disease (AD). Methods: 64 patients with AD were selected, and the admi...Objective: To analyze the clinical value of cognitive function training combined with daily life ability training in patients with Alzheimer's disease (AD). Methods: 64 patients with AD were selected, and the admission period was from January 2018 to January 2020. All patients were randomly divided into experimental group and control group, with 32 cases in each group. The therapeutic effects of the two groups were compared. Results: after intervention, the scores of MOCA and life ability of the two groups were increased compared with those before intervention, the experimental group increased significantly (P < 0.05). Compared with the control group, the MMSE score of the experimental group was significantly higher (P < 0.05). Conclusion: cognitive function training combined with activities of daily living training intervention for AD patients significantly improved their cognitive function and intellectual state and promoted their physical rehabilitation.展开更多
BACKGROUND Intracerebral hemorrhage mainly occurs in middle-aged and elderly patients with hypertension,and surgery is currently the main treatment for hypertensive cerebral hemorrhage,but the bleeding caused by surge...BACKGROUND Intracerebral hemorrhage mainly occurs in middle-aged and elderly patients with hypertension,and surgery is currently the main treatment for hypertensive cerebral hemorrhage,but the bleeding caused by surgery will cause damage to the patient's nerve cells,resulting in cognitive and motor dysfunction,resulting in a decline in the patient's quality of life.AIM To investigate associations between cerebral arterial blood flow and executive and cognitive functions in depressed patients after acute hypertensive cerebral hemorrhage.METHODS Eighty-nine patients with depression after acute hypertensive cerebral hemorrhage who were admitted to our hospital between January 2019 and July 2021 were selected as the observation group,while 100 patients without depression who had acute hypertensive cerebral hemorrhage were selected as the control group.The attention span of the patients was assessed using the Paddle Pin Test while executive function was assessed using the Wisconsin Card Sorting Test(WCST)and cognitive function was assessed using the Montreal Cognitive Assessment Scale(MoCA).The Hamilton Depression Rating Scale(HAMD-24)was used to evaluate the severity of depression of involved patients.Cerebral arterial blood flow was measured in both groups.RESULTS The MoCA score,net scores I,II,III,IV,and the total net score of the scratch test in the observation group were significantly lower than those in the control group(P<0.05).Concurrently,the total number of responses,number of incorrect responses,number of persistent errors,and number of completed responses of the first classification in the WCST test were significantly higher in the observation group than those in the control group(P<0.05).Blood flow in the basilar artery,left middle cerebral artery,right middle cerebral artery,left anterior cerebral artery,and right anterior cerebral artery was significantly lower in the observation group than in the control group(P<0.05).The basilar artery,left middle cerebral artery,right middle cerebral artery,left anterior cerebral artery,and right anterior cerebral artery were positively correlated with the net and total net scores of each part of the Paddle Pin test and the MoCA score(P<0.05),and negatively correlated with each part of the WCST test(P<0.05).In the observation group,the post-treatment improvement was more prominent in the Paddle Pin test,WCST test,HAMD-24 score,and MoCA score compared with those in the pre-treatment period(P<0.05).Blood flow in the basilar artery,left middle cerebral artery,right middle cerebral artery,left anterior cerebral artery,and right anterior cerebral artery significantly improved in the observation group after treatment(P<0.05).CONCLUSION Impaired attention,and executive and cognitive functions are correlated with cerebral artery blood flow in patients with depression after acute hypertensive cerebral hemorrhage and warrant further study.展开更多
In daily functional activities,the body needs the ability to perform two or more tasks at the same time(such as talking while walking).However,the gait disorder of patients with Parkinson's disease is aggravated w...In daily functional activities,the body needs the ability to perform two or more tasks at the same time(such as talking while walking).However,the gait disorder of patients with Parkinson's disease is aggravated when performing dual tasks,which seriously affects their quality of life.Therefore,the medical management plan should offer effective exercise training programming to improve Parkinson's disease patients'ability to perform dual tasks.Most traditional exercise intervention methods only focus on the perspective of exercise or cognition,ignoring their interaction,and fail to adequately resolve the dual task obstacles associated with Parkinson's disease.Some scholars put forward the concept of dual-task training and have applied dual-task training to pa-tients with neurological disorders and have achieved good therapeutic effects.Therefore,this article summarizes the research literature concerning dual-task training to improve cognitive impairment and walking function of Parkinson's disease patients,to evaluate and discuss possible mechanisms of action,and provide a basis for adjuvant treatment and rehabilitation of Parkinson's disease patients.展开更多
BACKGROUND:Hemiplegia,a prevalent stroke-related condition,is often studied for motor dysfunction;however,spasticity remains under-researched.Abnormal muscle tone significantly hinders hemiplegic patients’walking rec...BACKGROUND:Hemiplegia,a prevalent stroke-related condition,is often studied for motor dysfunction;however,spasticity remains under-researched.Abnormal muscle tone significantly hinders hemiplegic patients’walking recovery.OBJECTIVE:To determine whether early suspension-protected training with a personal assistant machine for stroke patients enhances walking ability and prevents muscle spasms.METHODS:Thirty-two early-stage stroke patients from Shenzhen University General Hospital and the China Rehabilitation Research Center were randomly assigned to the experimental group(n=16)and the control group(n=16).Both groups underwent 4 weeks of gait training under the suspension protection system for 30 minutes daily,5 days a week.The experimental group used the personal assistant machine during training.Three-dimensional gait analysis(using the Cortex motion capture system),Brunnstrom staging,Fugl-Meyer Assessment for lower limb motor function,Fugl-Meyer balance function,and the modified Ashworth Scale were evaluated within 1 week before the intervention and after 4 weeks of intervention.RESULTS AND CONCLUSION:After the 4-week intervention,all outcome measures showed significant changes in each group.The experimental group had a small but significant increase in the modified Ashworth Scale score(P<0.05,d=|0.15|),while the control group had a large significant increase(P<0.05,d=|1.48|).The experimental group demonstrated greater improvements in walking speed(16.5 to 38.44 cm/s,P<0.05,d=|4.01|),step frequency(46.44 to 64.94 steps/min,P<0.05,d=|2.32|),stride length(15.50 to 29.81 cm,P<0.05,d=|3.44|),and peak hip and knee flexion(d=|1.82|to|2.17|).After treatment,the experimental group showed significantly greater improvements than the control group in walking speed(38.44 vs.26.63 cm/s,P<0.05,d=|2.75|),stride length,peak hip and knee flexion(d=|1.31|to|1.45|),step frequency(64.94 vs.59.38 steps/min,P<0.05,d=|0.85|),and a reduced support phase(bilateral:24.31%vs.28.38%,P<0.05,d=|0.88|;non-paretic:66.19%vs.70.13%,P<0.05,d=|0.94|).For early hemiplegia,personal assistant machine-assisted gait training under the suspension protection system helps establish a correct gait pattern,prevents muscle spasms,and improves motor function.展开更多
Objective: to use early rehabilitation treatment for the patients with acute stroke hemiplegia, to observe and analyze its impact on the upper and lower limb function recovery and daily life ability. Methods: in June ...Objective: to use early rehabilitation treatment for the patients with acute stroke hemiplegia, to observe and analyze its impact on the upper and lower limb function recovery and daily life ability. Methods: in June 2021-June 2022 for intercept research time interval, a total of 60 cases of acute stroke hemiplegia, random principle specification grouping, control group received 30 cases of routine treatment, observation group received 30 cases of early rehabilitation treatment, around the upper and lower limb function assessment score, daily life ability evaluation score, balance function, cognitive function scale evaluation score and complication rate data line to compare. Results: before the treatment work, the evaluation results, daily life ability, balance function, and cognitive function evaluation results showed no difference (P> 0.05), and the results were higher (P <0.05);for the complication rate, the observation group showed lower results (P <0.05). Conclusion: for acute stroke cases, early rehabilitation treatment, which can improve the function of upper and lower limbs, strengthen their living ability, balance function and cognitive function, and prevent complications in patients, which is worthy of clinical application.展开更多
Cognitive enhancement is essential for maintaining the quality of life in healthy individuals and improving the ability of those with mental impairments.In recent years,noninvasive neuromodulation techniques(such as t...Cognitive enhancement is essential for maintaining the quality of life in healthy individuals and improving the ability of those with mental impairments.In recent years,noninvasive neuromodulation techniques(such as transcranial magnetic stimulation,transcranial direct-current stimulation,and transcranial ultrasound stimulation)have shown significant potential in enhancing cognitive functions[1,2].Existing technologies are limited mainly to superficial cortical regions,with limited efficacy in targeting deep brain areas and inadequate methods for evaluating their modulatory effects.Selecting stimulation parameters(such as locus,depth,and intensity)and assessing the impact of neuromodulation remains incompletely understood.展开更多
Background: Water weight-loss walking training is an emerging physical therapy technique, which provides new ideas for improving the motor function of stroke patients and improving the quality of life of patients. How...Background: Water weight-loss walking training is an emerging physical therapy technique, which provides new ideas for improving the motor function of stroke patients and improving the quality of life of patients. However, the rehabilitation effect of water weight-loss training in stroke patients is currently unclear. Objective: To analyze the effect of water weight loss walking training in stroke patients. Methods: A total of 180 stroke patients admitted to our hospital from January 2019 to December 2021 were selected and randomly divided into two groups. The control group received routine walking training, and the research group performed weight loss walking training in water on this basis. The lower limb motor function, muscle tone grade, daily living ability, gait and balance ability were compared between the two groups before and after treatment. Results: Compared with the control group, the FMA-LE score (Fugl-Meyer motor assessment of Lower Extremity), MBI score (Modified Barthel Index) and BBS score (berg balance scale) of the study group were higher after treatment, and the muscle tone was lower (P Conclusion: Water weight loss walking training can enhance patients’ muscle tension, correct patients’ abnormal gait, improve patients’ balance and walking ability, and contribute to patients’ motor function recovery and self-care ability improvement.展开更多
目的探讨感知压力及其不同亚型与中国中老年人认知功能及轻度认知障碍(mild cognitive impairment,MCI)的关联,为制定精准干预策略提供科学依据。方法利用2018年中国健康与营养调查(China Health and Nutrition Survey,CHNS)数据,选取40...目的探讨感知压力及其不同亚型与中国中老年人认知功能及轻度认知障碍(mild cognitive impairment,MCI)的关联,为制定精准干预策略提供科学依据。方法利用2018年中国健康与营养调查(China Health and Nutrition Survey,CHNS)数据,选取40~80岁中老年人。采用10个条目感知压力量表(perceived stress scale with 10 items,PSS-10)评估感知压力,并根据压力带来的痛苦感与应对压力能力2个因子的中位数将调查对象分为4个压力亚型组。认知功能通过简易精神状态检查(mini-mental state examination,MMSE)评估,MCI判定依据文化程度调整的切点值。采用Tobit回归和logistic回归分析压力与认知功能及MCI的关联。结果纳入40~80岁中老年人共9257名,在调整协变量后,PSS-10总分每增加1分,MMSE得分降低0.20分(P<0.001),MCI风险增加8%(OR=1.08,95%CI:1.06~1.09);PSS-10得分最高四分位组的认知功能得分比最低四分位组低2.78分(P<0.001),MCI患病风险增加1.74倍(OR=2.74,95%CI:2.31~3.25);与低压力/高应对能力者相比,高压力/低应对能力者和高压力/高应对能力者认知功能得分分别降低2.56和1.79分(P<0.001),MCI患病风险分别增加1.62倍(OR=2.62,95%CI:2.25~3.05)和0.90倍(OR=1.90,95%CI:1.61~2.25)。结论感知压力是中国中老年人认知功能下降和MCI的重要风险因素,应对能力可在一定程度上缓解压力的负面影响,建议在认知功能障碍预防策略中同时关注压力管理和应对能力提升。展开更多
文摘Objective: To analyze the clinical value of cognitive function training combined with daily life ability training in patients with Alzheimer's disease (AD). Methods: 64 patients with AD were selected, and the admission period was from January 2018 to January 2020. All patients were randomly divided into experimental group and control group, with 32 cases in each group. The therapeutic effects of the two groups were compared. Results: after intervention, the scores of MOCA and life ability of the two groups were increased compared with those before intervention, the experimental group increased significantly (P < 0.05). Compared with the control group, the MMSE score of the experimental group was significantly higher (P < 0.05). Conclusion: cognitive function training combined with activities of daily living training intervention for AD patients significantly improved their cognitive function and intellectual state and promoted their physical rehabilitation.
文摘BACKGROUND Intracerebral hemorrhage mainly occurs in middle-aged and elderly patients with hypertension,and surgery is currently the main treatment for hypertensive cerebral hemorrhage,but the bleeding caused by surgery will cause damage to the patient's nerve cells,resulting in cognitive and motor dysfunction,resulting in a decline in the patient's quality of life.AIM To investigate associations between cerebral arterial blood flow and executive and cognitive functions in depressed patients after acute hypertensive cerebral hemorrhage.METHODS Eighty-nine patients with depression after acute hypertensive cerebral hemorrhage who were admitted to our hospital between January 2019 and July 2021 were selected as the observation group,while 100 patients without depression who had acute hypertensive cerebral hemorrhage were selected as the control group.The attention span of the patients was assessed using the Paddle Pin Test while executive function was assessed using the Wisconsin Card Sorting Test(WCST)and cognitive function was assessed using the Montreal Cognitive Assessment Scale(MoCA).The Hamilton Depression Rating Scale(HAMD-24)was used to evaluate the severity of depression of involved patients.Cerebral arterial blood flow was measured in both groups.RESULTS The MoCA score,net scores I,II,III,IV,and the total net score of the scratch test in the observation group were significantly lower than those in the control group(P<0.05).Concurrently,the total number of responses,number of incorrect responses,number of persistent errors,and number of completed responses of the first classification in the WCST test were significantly higher in the observation group than those in the control group(P<0.05).Blood flow in the basilar artery,left middle cerebral artery,right middle cerebral artery,left anterior cerebral artery,and right anterior cerebral artery was significantly lower in the observation group than in the control group(P<0.05).The basilar artery,left middle cerebral artery,right middle cerebral artery,left anterior cerebral artery,and right anterior cerebral artery were positively correlated with the net and total net scores of each part of the Paddle Pin test and the MoCA score(P<0.05),and negatively correlated with each part of the WCST test(P<0.05).In the observation group,the post-treatment improvement was more prominent in the Paddle Pin test,WCST test,HAMD-24 score,and MoCA score compared with those in the pre-treatment period(P<0.05).Blood flow in the basilar artery,left middle cerebral artery,right middle cerebral artery,left anterior cerebral artery,and right anterior cerebral artery significantly improved in the observation group after treatment(P<0.05).CONCLUSION Impaired attention,and executive and cognitive functions are correlated with cerebral artery blood flow in patients with depression after acute hypertensive cerebral hemorrhage and warrant further study.
基金supported by National key R&D projects(2019YFF0301805)the Science and Technology Innovation Project of Dalian,China(ZX20180690).
文摘In daily functional activities,the body needs the ability to perform two or more tasks at the same time(such as talking while walking).However,the gait disorder of patients with Parkinson's disease is aggravated when performing dual tasks,which seriously affects their quality of life.Therefore,the medical management plan should offer effective exercise training programming to improve Parkinson's disease patients'ability to perform dual tasks.Most traditional exercise intervention methods only focus on the perspective of exercise or cognition,ignoring their interaction,and fail to adequately resolve the dual task obstacles associated with Parkinson's disease.Some scholars put forward the concept of dual-task training and have applied dual-task training to pa-tients with neurological disorders and have achieved good therapeutic effects.Therefore,this article summarizes the research literature concerning dual-task training to improve cognitive impairment and walking function of Parkinson's disease patients,to evaluate and discuss possible mechanisms of action,and provide a basis for adjuvant treatment and rehabilitation of Parkinson's disease patients.
文摘BACKGROUND:Hemiplegia,a prevalent stroke-related condition,is often studied for motor dysfunction;however,spasticity remains under-researched.Abnormal muscle tone significantly hinders hemiplegic patients’walking recovery.OBJECTIVE:To determine whether early suspension-protected training with a personal assistant machine for stroke patients enhances walking ability and prevents muscle spasms.METHODS:Thirty-two early-stage stroke patients from Shenzhen University General Hospital and the China Rehabilitation Research Center were randomly assigned to the experimental group(n=16)and the control group(n=16).Both groups underwent 4 weeks of gait training under the suspension protection system for 30 minutes daily,5 days a week.The experimental group used the personal assistant machine during training.Three-dimensional gait analysis(using the Cortex motion capture system),Brunnstrom staging,Fugl-Meyer Assessment for lower limb motor function,Fugl-Meyer balance function,and the modified Ashworth Scale were evaluated within 1 week before the intervention and after 4 weeks of intervention.RESULTS AND CONCLUSION:After the 4-week intervention,all outcome measures showed significant changes in each group.The experimental group had a small but significant increase in the modified Ashworth Scale score(P<0.05,d=|0.15|),while the control group had a large significant increase(P<0.05,d=|1.48|).The experimental group demonstrated greater improvements in walking speed(16.5 to 38.44 cm/s,P<0.05,d=|4.01|),step frequency(46.44 to 64.94 steps/min,P<0.05,d=|2.32|),stride length(15.50 to 29.81 cm,P<0.05,d=|3.44|),and peak hip and knee flexion(d=|1.82|to|2.17|).After treatment,the experimental group showed significantly greater improvements than the control group in walking speed(38.44 vs.26.63 cm/s,P<0.05,d=|2.75|),stride length,peak hip and knee flexion(d=|1.31|to|1.45|),step frequency(64.94 vs.59.38 steps/min,P<0.05,d=|0.85|),and a reduced support phase(bilateral:24.31%vs.28.38%,P<0.05,d=|0.88|;non-paretic:66.19%vs.70.13%,P<0.05,d=|0.94|).For early hemiplegia,personal assistant machine-assisted gait training under the suspension protection system helps establish a correct gait pattern,prevents muscle spasms,and improves motor function.
文摘Objective: to use early rehabilitation treatment for the patients with acute stroke hemiplegia, to observe and analyze its impact on the upper and lower limb function recovery and daily life ability. Methods: in June 2021-June 2022 for intercept research time interval, a total of 60 cases of acute stroke hemiplegia, random principle specification grouping, control group received 30 cases of routine treatment, observation group received 30 cases of early rehabilitation treatment, around the upper and lower limb function assessment score, daily life ability evaluation score, balance function, cognitive function scale evaluation score and complication rate data line to compare. Results: before the treatment work, the evaluation results, daily life ability, balance function, and cognitive function evaluation results showed no difference (P> 0.05), and the results were higher (P <0.05);for the complication rate, the observation group showed lower results (P <0.05). Conclusion: for acute stroke cases, early rehabilitation treatment, which can improve the function of upper and lower limbs, strengthen their living ability, balance function and cognitive function, and prevent complications in patients, which is worthy of clinical application.
基金supported by the National Natural Science Foundation of China(82172018 and 62333002).
文摘Cognitive enhancement is essential for maintaining the quality of life in healthy individuals and improving the ability of those with mental impairments.In recent years,noninvasive neuromodulation techniques(such as transcranial magnetic stimulation,transcranial direct-current stimulation,and transcranial ultrasound stimulation)have shown significant potential in enhancing cognitive functions[1,2].Existing technologies are limited mainly to superficial cortical regions,with limited efficacy in targeting deep brain areas and inadequate methods for evaluating their modulatory effects.Selecting stimulation parameters(such as locus,depth,and intensity)and assessing the impact of neuromodulation remains incompletely understood.
文摘Background: Water weight-loss walking training is an emerging physical therapy technique, which provides new ideas for improving the motor function of stroke patients and improving the quality of life of patients. However, the rehabilitation effect of water weight-loss training in stroke patients is currently unclear. Objective: To analyze the effect of water weight loss walking training in stroke patients. Methods: A total of 180 stroke patients admitted to our hospital from January 2019 to December 2021 were selected and randomly divided into two groups. The control group received routine walking training, and the research group performed weight loss walking training in water on this basis. The lower limb motor function, muscle tone grade, daily living ability, gait and balance ability were compared between the two groups before and after treatment. Results: Compared with the control group, the FMA-LE score (Fugl-Meyer motor assessment of Lower Extremity), MBI score (Modified Barthel Index) and BBS score (berg balance scale) of the study group were higher after treatment, and the muscle tone was lower (P Conclusion: Water weight loss walking training can enhance patients’ muscle tension, correct patients’ abnormal gait, improve patients’ balance and walking ability, and contribute to patients’ motor function recovery and self-care ability improvement.
文摘目的探讨感知压力及其不同亚型与中国中老年人认知功能及轻度认知障碍(mild cognitive impairment,MCI)的关联,为制定精准干预策略提供科学依据。方法利用2018年中国健康与营养调查(China Health and Nutrition Survey,CHNS)数据,选取40~80岁中老年人。采用10个条目感知压力量表(perceived stress scale with 10 items,PSS-10)评估感知压力,并根据压力带来的痛苦感与应对压力能力2个因子的中位数将调查对象分为4个压力亚型组。认知功能通过简易精神状态检查(mini-mental state examination,MMSE)评估,MCI判定依据文化程度调整的切点值。采用Tobit回归和logistic回归分析压力与认知功能及MCI的关联。结果纳入40~80岁中老年人共9257名,在调整协变量后,PSS-10总分每增加1分,MMSE得分降低0.20分(P<0.001),MCI风险增加8%(OR=1.08,95%CI:1.06~1.09);PSS-10得分最高四分位组的认知功能得分比最低四分位组低2.78分(P<0.001),MCI患病风险增加1.74倍(OR=2.74,95%CI:2.31~3.25);与低压力/高应对能力者相比,高压力/低应对能力者和高压力/高应对能力者认知功能得分分别降低2.56和1.79分(P<0.001),MCI患病风险分别增加1.62倍(OR=2.62,95%CI:2.25~3.05)和0.90倍(OR=1.90,95%CI:1.61~2.25)。结论感知压力是中国中老年人认知功能下降和MCI的重要风险因素,应对能力可在一定程度上缓解压力的负面影响,建议在认知功能障碍预防策略中同时关注压力管理和应对能力提升。
