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A practical approach to the difficult urethral catheterization for urology trainees
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作者 Wyatt MacNevin Daniel T.Keefe +1 位作者 Karen Milford Nicholas R.Paterson 《The Canadian Journal of Urology》 2025年第1期5-13,共9页
Urethral catheterization is an important skill to develop as consultations for“difficult catheterization”are common in practice.Developing a broad approach to difficult urethral catheterization is crucial to improve... Urethral catheterization is an important skill to develop as consultations for“difficult catheterization”are common in practice.Developing a broad approach to difficult urethral catheterization is crucial to improve trainee success rates.Strategies and techniques to improve catheterization success are often passed down and shared between trainees without formal documentation or dissemination of techniques.Herein,we present a framework for difficult urethral catheterization based on clinical history and patient examination,while also providing additional techniques and troubleshooting to overcome common challenges with urethral catheterization in adult and pediatric patients. 展开更多
关键词 urethral catheterization difficult catheterization pediatric catheterization urology trainees catheter
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The Study of Ultrasound-Guided Central Venous Catheterization in the Teaching of Anesthesia Residents
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作者 Yanjun Liu Yufang Wang +2 位作者 Hanwei Dan Chun Chen Ming Zhang 《Journal of Biosciences and Medicines》 2025年第1期264-271,共8页
Objective: To evaluate the application effect of ultrasound-guided central venous catheterization in the teaching of anesthesia residents. Methods: Forty anesthesia resident companions who received standardized reside... Objective: To evaluate the application effect of ultrasound-guided central venous catheterization in the teaching of anesthesia residents. Methods: Forty anesthesia resident companions who received standardized residency training in our department from July 2018 to July 2020 were randomly divided into an ultrasound group and a control group, with 20 participants in each group. The ultrasound group was taught by ultrasound-guided central venipuncture, while the control group was taught by traditional anatomy. After ten training punctures, all trainees were assessed twice. Results: Both groups could master the technique of central venipuncture. The success rate of first puncture and the overall success rate of puncture in the ultrasound group were significantly higher than those in the control group (p p < 0.05). Conclusion: Compared with the traditional anatomical localization teaching, the use of ultrasound-guided technology can improve the success rate of puncture, save puncture time, reduce related complications, and have a better training effect. 展开更多
关键词 ULTRASOUND Central Venous catheterization
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Improving outcomes in foley catheterization:A retrospective review with a proposed protocol
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作者 Jordan Sarver Remington Farley +2 位作者 Shane Daugherty Jordan Bilbrew Joshua Palka 《World Journal of Nephrology》 2025年第2期86-94,共9页
BACKGROUND Urologists are commonly consulted regarding difficult and traumatic urethral catheterizations.Complications surrounding Foley catheterizations represent a significant burden to the healthcare system.AIM To ... BACKGROUND Urologists are commonly consulted regarding difficult and traumatic urethral catheterizations.Complications surrounding Foley catheterizations represent a significant burden to the healthcare system.AIM To assess the demographic and patient characteristics surrounding urological consultation for difficult and traumatic Foley catheterizations at our institution across multiple hospitals.METHODS This is a single-institution,multi-hospital,263 patient,retrospective chart review from Jan 2020–December 2023.RESULTS The majority of consultations(80.2%)did not require heroic measures by the urology service.A Foley catheter placement was determined not difficult in the majority 191(72.6%)of patients.Sub-group analysis of“difficult by urology”vs“not difficult by urology”,showed a significant difference between those with zero attempts,one attempt,and greater than one attempts(P=0.004).Those patients specifically with greater than one attempts were more likely to be seen as a difficult insertion by urology assessment(60.6%)compared to not difficult(38.6%).Likewise,those patients with a history of difficult urethral catheter(DUC)/traumatic urethral catheterization(TUC)(25.8%)were more likely to be difficult compared to those without a history of DUC/TUC(14.2%)(P=0.038).CONCLUSION The study found that majority of consultations received did not require heroic measures by the urology service to place a catheter.Patients who had a history of DUC/TUC and those who had greater than one catheter attempts were statistically more likely to be a DUC based on urology assessment.At our institution we hope to propose a protocol in which nursing staff and non-urologic clinicians will utilize a troubleshooting checklist and an algorithm when difficult or traumatic urethral catheters are encountered in order to improve patient care and decrease healthcare costs.For example,this protocol would ideally address complications of multiple catheter attempts such as urethral trauma,development of urethral strictures,and infection risk.Additionally,future trainings and availability of additional resources will be provided and assessed with a goal of reducing healthcare cost surrounding these complications. 展开更多
关键词 Patient care Education Traumatic catheter Difficult catheter Foley catheter UROLOGY
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加味温胆汤对围绝经期失眠痰热型患者血清5-HT、MT、TNF-α及性激素水平的影响 被引量:1
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作者 王艳 徐月霞 丁炜 《中国实验方剂学杂志》 北大核心 2025年第9期12-18,共7页
目的:探讨加味温胆汤在围绝经期失眠痰热型患者治疗中的应用价值,观察其对神经递质及体脂肪的影响。方法:162例围绝经期失眠痰热型患者均于2021年5月至2023年11月在南京医科大学第一附属医院中医科就诊,纳入研究前均随机分组。对照组81... 目的:探讨加味温胆汤在围绝经期失眠痰热型患者治疗中的应用价值,观察其对神经递质及体脂肪的影响。方法:162例围绝经期失眠痰热型患者均于2021年5月至2023年11月在南京医科大学第一附属医院中医科就诊,纳入研究前均随机分组。对照组81例用西医常规治疗,观察组81例联合加味温胆汤治疗,治疗4周。结果:与本组治疗前比较,治疗后两组血清白细胞介素-β(IL-1β)、肿瘤坏死因子-α(TNF-α)降低,多巴胺(DA)、褪黑素(MT)、5-羟色胺(5-HT)升高(P<0.05);治疗后与对照组比较,观察组上述指标改善更优(P<0.05);与本组治疗前比较,治疗后两组卵泡刺激素(FSH)、黄体生成素(LH)水平降低,雌二醇(E_(2))水平升高(P<0.05);治疗后与对照组比较,观察组上述性激素指标改善更优(P<0.05);与本组治疗前比较,治疗后两组快速眼动睡眠期(REM)时间、总睡眠时间(TST)延长,睡眠潜伏期(SL)缩短(P<0.05);治疗后与对照组比较,观察组睡眠情况改善更优(P<0.05);与本组治疗前比较,治疗后两组匹兹堡睡眠质量指数(PSQI)、中医总症状积分降低(P<0.05);治疗后与对照组比较,观察组PSQI、中医总症状积分改善更优(P<0.05);观察组总有效率93.83%(76/81),对照组总有效率82.72%(67/81)(χ^(2)=9.135,P<0.05)。结论:对于围绝经期失眠痰热型患者而言应用加味温胆汤有助于调控神经递质,调控炎性因子水平,改善性激素水平,提高睡眠质量,提高疗效。 展开更多
关键词 加味温胆汤 围绝经期失眠 痰热型 神经递质 褪黑素(mt) 肿瘤坏死因子-α(TNF-α) 性激素 睡眠质量
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How to manage the malposition of deep vein catheterization into the artery? 被引量:1
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作者 Jun-Na SUN Hai DONG +4 位作者 Peng CHEN Zi-Qi LI Li-You SUI Bin QI Quan-Min JING 《Journal of Geriatric Cardiology》 SCIE CAS CSCD 2024年第6期682-685,共4页
Central venous catheterization establishes temporary,efficient,and rapid use of deep venous access in patients,which provides high flow rate fluid perfusion,enables measurement of central venous pressure,and acts as a... Central venous catheterization establishes temporary,efficient,and rapid use of deep venous access in patients,which provides high flow rate fluid perfusion,enables measurement of central venous pressure,and acts as an important reference for clinical decision-making.However,various complications such as pneumothorax,hemothorax,hematoma,and puncture failure can easily occur during the puncture and catheterization process. 展开更多
关键词 PROCESS enable catheter
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Anatomical variation in the internal jugular vein:potential risk factors for central venous catheterization-a case report
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作者 Yidan Shan Weijia Huang 《World Journal of Emergency Medicine》 SCIE CAS CSCD 2024年第4期316-318,共3页
Central venous catheterization(CVC)is an invasive medical procedure used to measure central venous pressure and provides a stable route for continuous drug administration.CVC is widely used in the emergency department... Central venous catheterization(CVC)is an invasive medical procedure used to measure central venous pressure and provides a stable route for continuous drug administration.CVC is widely used in the emergency department and intensive care units.It is typically performed by inserting a catheter through the internal jugular vein(IJV)into the superior vena cava near the right atrium.[1,2]While catheterization is a fundamental skill proficiently performed by healthcare professionals,lethal complications may occasionally occur because of undesirable positioning,depth and diameter. 展开更多
关键词 VENOUS catheter JUGULAR
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甜菜BvMT2基因的生物信息学及镉应答特性分析
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作者 黄烁淇 赵桂龙 +2 位作者 赵晓鑫 刘大丽 鲁振强 《中国糖料》 2025年第4期1-10,共10页
【目的】金属硫蛋白(Metallothionein,MT)作为生物体内广泛存在的金属结合蛋白,在植物抵抗重金属胁迫中发挥着重要作用。为探究甜菜金属硫蛋白2(BvMT2)对重金属镉(Cd)胁迫的应答特性。【方法】利用RT-PCR技术克隆了BvMT2基因,并通过生... 【目的】金属硫蛋白(Metallothionein,MT)作为生物体内广泛存在的金属结合蛋白,在植物抵抗重金属胁迫中发挥着重要作用。为探究甜菜金属硫蛋白2(BvMT2)对重金属镉(Cd)胁迫的应答特性。【方法】利用RT-PCR技术克隆了BvMT2基因,并通过生物信息学方法预测了该基因的顺式作用元件、上游转录因子、理化性质等,分析了其在不同浓度Cd胁迫下的转录表达特性。【结果】该基因编码区全长225 bp,生信分析结果表明其相对分子质量为1909.91 Da,理论等电点为4.55,半胱氨酸(Cys)和甘氨酸(Gly)含量较高,属于定位于细胞核或叶绿体中的不稳定非分泌性亲水蛋白。BvMT2含有CGTCA-motif、生长素类、光响应、具有保守序列的部分光响应元件、MYB结合、厌氧诱导和调节等7个相关的顺式作用元件,并且转录因子BVRB_7g177640和BVRB_3g048050可能参与BvMT2的转录调控过程。转录组数据表明BvMT2在1、3和5 mmol/L Cd浓度胁迫下均显著上调。【结论】综上所述,BvMT2参与甜菜Cd逆境应答过程。本研究为BvMT2应对重金属胁迫的功能研究奠定了基础,为进一步解析甜菜应对重金属污染的响应机制提供依据。 展开更多
关键词 甜菜 金属硫蛋白(mt) 镉胁迫 生物信息学 转录表达特性
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MT-9000与IOLMaster 700测量白内障患者眼生物学参数的一致性
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作者 吴国欢 张莹 +3 位作者 杜潮玉 黄晶晶 王利满 王勤美 《中华实验眼科杂志(中英文)》 北大核心 2025年第10期924-929,共6页
目的分析新型可视化扫频生物测量仪MT-9000与IOLMaster 700在测量年龄相关性白内障患者术前眼部生物学参数方面的一致性。方法采用横断面研究, 连续纳入2024年6月20日至8月22日在武汉大学附属爱尔眼科医院就诊的拟行白内障摘出联合人工... 目的分析新型可视化扫频生物测量仪MT-9000与IOLMaster 700在测量年龄相关性白内障患者术前眼部生物学参数方面的一致性。方法采用横断面研究, 连续纳入2024年6月20日至8月22日在武汉大学附属爱尔眼科医院就诊的拟行白内障摘出联合人工晶状体植入术的患者536例536眼, 所有患者分别使用2种可视化扫频生物测量仪MT-9000和IOLMaster 700进行生物学参数测量, 获取的参数包括眼轴长度(AL)、角膜直径(WTW)、前房深度(ACD)、晶状体厚度(LT)、中央角膜厚度(CCT)和平均角膜曲率(Km)。比较2种仪器AL的检出率及各参数差异, 分析检查结果的相关性和一致性。基于MT-9000测量的AL将患者分为短眼轴组(AL<22 mm)27眼、正常眼轴组(22≤AL≤25 mm)392眼和长眼轴组(AL>25 mm)104眼, 比较测得的AL在不同亚组中的结果差异。结果 MT-9000对AL的检出率为99.3%(532/536), 高于IOLMaster 700的97.6%(523/536), 差异有统计学意义(χ^(2)=4.841, P=0.028);MT-9000测得的AL、LT、Km均比IOLMaster 700高, 差异均有统计学意义(Z=6.418, P<0.001;t=4.971、5.179, 均P<0.001);MT-9000测得的WTW、CCT均较IOLMaster 700低, 差异均有统计学意义(Z=-3.017, P<0.05;t=16.322, P<0.05)。基于MT-9000测量值将AL进行分组后, 短眼轴组及正常眼轴组中MT-9000与IOLMaster 700测得的AL差异均无统计学意义(Z=-1.530, P=0.126;t=-0.880, P=0.380);长眼轴组中MT-9000测得的AL比IOLMaster 700长, 差异有统计学意义(Z=7.254, P<0.001)。MT-9000与IOLMaster 700测得的AL、WTW、ACD、LT、CCT、Km的组内相关系数分别为1.000、0.616、0.997、0.999、0.988和0.995(均P<0.001)。Bland-Altman分析2种仪器测量的AL、WTW、ACD、LT、CCT、Km的95%一致性界限(LoA)分别为-0.06~+0.08 mm、-0.64~+0.57 mm、-0.06~+0.06 mm、-0.04~+0.05 mm、-13.6~+6.3 μm和-0.26~+0.32 D, 分别有6.5%、3.6%、5.3%、6.3%、6.5%和4.4%的数据点位于95%LoA外。结论 MT-9000测量的白内障患者术前的AL、ACD、LT、CCT、Km与IOLMaster 700展现出良好的一致性, 适用于白内障术前生物学参数测量;两者测得的WTW一致性欠佳, 不建议互换使用。MT-9000在AL检出率方面表现优于IOLMaster 700。 展开更多
关键词 光学相干断层扫描 白内障 可视化 生物测量 mt-9000 IOLMaster 700
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麝鼠前列腺Mt1基因的季节性表达及蛋白功能预测
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作者 赵丙辰 张宇 +2 位作者 李澍祺 华思锐 白素英 《黑龙江动物繁殖》 2025年第3期38-44,共7页
试验旨在探究麝鼠前列腺组织中褪黑素受体1(Mt1)基因的季节性表达差异,并解析其RNA及蛋白结构特征与功能。采集繁殖期与非繁殖期麝鼠前列腺组织,通过荧光定量PCR检测Mt1的mRNA表达水平,结合mRNA二级结构预测、蛋白理化性质分析、跨膜结... 试验旨在探究麝鼠前列腺组织中褪黑素受体1(Mt1)基因的季节性表达差异,并解析其RNA及蛋白结构特征与功能。采集繁殖期与非繁殖期麝鼠前列腺组织,通过荧光定量PCR检测Mt1的mRNA表达水平,结合mRNA二级结构预测、蛋白理化性质分析、跨膜结构及蛋白互作预测,揭示其在季节性繁殖中的潜在作用机制。结果表明:非繁殖期麝鼠前列腺中Mt1的mRNA表达量极显著高于繁殖期(P<0.0001),表明其可能参与非繁殖期组织稳态维持。mRNA结构预测显示,Mt1基因RNA具有多茎环构象(最小自由能MFE=-1444.7 kJ/mol);Mt1蛋白含7次跨膜螺旋(覆盖161个氨基酸),理论等电点pI=9.45,疏水性强,胞外结构域含12个半胱氨酸残基,可能通过二硫键稳定构象。SMART结构域预测显示,其属于Srsx亚家族,与精子发生相关蛋白功能特征相符。互作网络预测表明,Mt1蛋白的互作网络高度依赖G蛋白异源三聚体(Gαi/Gβγ),Gpr50可能作为调控因子参与其中,推测非繁殖期Mt1的高表达可能通过与Gαi亚基、Gβγ复合物及潜在调控受体Gpr50相互作用,调控前列腺代谢状态,从而适应长日照环境下的生殖抑制需求。综上,麝鼠前列腺中Mt1基因的极显著季节性表达通过其多茎环RNA结构、跨膜蛋白特性及G蛋白互作网络调控前列腺代谢,介导长日照环境下季节性生殖抑制的分子适应机制。 展开更多
关键词 麝鼠 前列腺 季节性繁殖 mt1基因 生物信息学分析
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镉对牛肝成纤维细胞MT基因表达和细胞凋亡的影响
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作者 张凯凯 赵元峰 +2 位作者 胡荣斌 冉江 代国滔 《黑龙江畜牧兽医》 北大核心 2025年第3期13-20,共8页
为探究镉对牛肝成纤维细胞MT基因表达及细胞凋亡的影响,试验分别用不同浓度(0.625,1.25,2.5,5,10μmol/L)镉处理牛肝成纤维细胞24 h和48 h,观察细胞形态;采用实时荧光定量PCR方法检测各处理细胞中MT基因的相对表达量,并采用流式细胞术... 为探究镉对牛肝成纤维细胞MT基因表达及细胞凋亡的影响,试验分别用不同浓度(0.625,1.25,2.5,5,10μmol/L)镉处理牛肝成纤维细胞24 h和48 h,观察细胞形态;采用实时荧光定量PCR方法检测各处理细胞中MT基因的相对表达量,并采用流式细胞术分别检测细胞的凋亡情况和细胞周期。结果表明:随着镉处理时间和浓度的增加,牛肝成纤维细胞的损伤逐渐加剧。处理24 h,与对照(未用镉处理的牛肝成纤维细胞)相比,1.25μmol/L镉处理的细胞中MT基因的相对表达量显著提高(P<0.05),2.5,5,10μmol/L镉处理的细胞中MT基因的相对表达量极显著提高(P<0.01),1.25μmol/L镉处理的细胞中MT基因的相对表达量显著提高(P<0.05),0.625μmol/L镉处理的细胞中MT基因的相对表达量差异不显著(P>0.05);处理48 h,与对照相比,0.625,1.25,2.5,5μmol/L镉处理的细胞中MT基因的相对表达量极显著提高(P<0.01),10μmol/L镉处理的细胞中MT基因的相对表达量差异不显著(P>0.05)。处理24 h,与对照相比,不同浓度镉处理的细胞凋亡率均差异不显著(P>0.05);处理48 h,2.5,5μmol/L镉处理的细胞凋亡率显著提高(P<0.05),10μmol/L镉处理的细胞凋亡率极显著提高(P<0.01),0.625,1.25μmol/L镉处理的细胞凋亡率差异不显著(P>0.05)。处理24 h,与对照相比,10μmol/L镉处理的细胞中G1期细胞占比极显著提高(P<0.01),0.625,1.25,2.5,5μmol/L镉处理的细胞中G1期细胞占比差异不显著(P>0.05);2.5μmol/L镉处理的细胞中S+G2期细胞占比显著降低(P<0.05),10μmol/L镉处理的细胞中S+G2期细胞占比极显著降低(P<0.01),0.625,1.25,5μmol/L镉处理的细胞中S+G2期细胞占比差异不显著(P>0.05)。处理48 h,与对照相比,0.625μmol/L镉处理的细胞中G1期细胞占比显著降低(P<0.05),5μmol/L镉处理的细胞中G1期细胞占比极显著提高(P<0.01),1.25,5,10μmol/L镉处理的细胞中G1期细胞占比差异不显著(P>0.05);0.625μmol/L镉处理的细胞中S+G2期细胞占比显著提高(P<0.05),5μmol/L镉处理的细胞中S+G2期细胞占比极显著降低(P<0.01),1.25,5,10μmol/L镉处理的细胞中S+G2期细胞占比差异不显著(P>0.05)。说明镉可导致牛肝成纤维细胞损伤,促进细胞中MT基因的表达,长时间(48 h)镉暴露会促进细胞凋亡,但长时间高浓度(2.5μmol/L以上)镉暴露会使MT基因表达量降低,同时高浓度镉会促进G1期细胞增殖,抑制S+G2期细胞增殖。 展开更多
关键词 牛肝成纤维细胞 mt基因 细胞凋亡 细胞周期
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基于频域Hampel识别的海洋MT数据脉冲噪声压制方法
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作者 徐天 罗鸣 《石油物探》 北大核心 2025年第4期667-678,共12页
海洋大地电磁法(MT)利用海底电磁台站(OBEM)接收天然大地电磁信号,利用阻抗张量估计方法计算视电阻率与相位,进而探测海底电性结构。OBEM产生的噪声常表现为具有特定频率特征的不规则高频脉冲,这种噪声导致受干扰频点的阻抗张量偏离真实... 海洋大地电磁法(MT)利用海底电磁台站(OBEM)接收天然大地电磁信号,利用阻抗张量估计方法计算视电阻率与相位,进而探测海底电性结构。OBEM产生的噪声常表现为具有特定频率特征的不规则高频脉冲,这种噪声导致受干扰频点的阻抗张量偏离真实值,严重影响数据解释。为降低脉冲噪声对海洋MT信号的影响,提出了一种基于频域Hampel识别的脉冲噪声压制方法。该方法利用一阶差分预白降低海洋MT数据的低频能量以提高Hampel识别器的噪声识别率,在频域利用Hampel识别器识别出大地电磁四分量中的脉冲噪声所在频点,考虑到大地电磁阻抗估计的稳定性,合并四分量噪声频点并做统一的降幅处理以压制脉冲噪声,达到校正视电阻率和相位畸变的目的。为评价基于频域Hampel识别的脉冲噪声压制方法的脉冲噪声压制效果,基于MT信号和脉冲噪声之间的周期性差异,利用自相关函数进行定性评价,该评价方法可应用于实测数据的噪声压制效果评价。将基于频域Hampel识别的脉冲噪声压制方法应用于合成数据和实测海洋大地电磁数据脉冲噪声压制实验,结果表明,所提出方法可压制海洋MT数据中的脉冲噪声,消减自相关函数曲线中噪声引起的周期峰,校正噪声引起的视电阻率和相位的畸变,提高了.MT数据的质量。 展开更多
关键词 海洋大地电磁法 脉冲噪声 Hampel识别器 自相关函数 噪声压制
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Analysis of the Nursing Effect of Hierarchical Extended Nursing Based on The Guidance of Orem’s Theory in Patients with PICC Catheterization
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作者 Haixia Zhu Shuqiao Chen Hui Chi 《Journal of Clinical and Nursing Research》 2024年第3期215-219,共5页
Objective:To analyze the nursing effect of hierarchical extended nursing based on the guidance of Orem’s theory in patients with peripherally inserted central(PICC)catheterization.Methods:Ninety-one patients with PIC... Objective:To analyze the nursing effect of hierarchical extended nursing based on the guidance of Orem’s theory in patients with peripherally inserted central(PICC)catheterization.Methods:Ninety-one patients with PICC catheterization admitted to the hospital from May 2021 to May 2023 were selected and divided into a control group and an observation group,with 45 and 46 cases,respectively.The control group received routine nursing care,while the observation group received routine nursing care combined with hierarchical extended nursing based on the guidance of Orem’s theory for 3 months.Relevant indicators between the two groups were compared.Results:The improvement degree of various indicators in the observation group after nursing was better than that of the control group(P<0.05).Conclusion:Graded extended nursing based on the guidance of Orem’s theory improved the knowledge,belief,behavior,and self-efficacy of patients with PICC catheterization,and relieved their anxiety,depression,and other negative emotions.The nursing effect was deemed to be significant. 展开更多
关键词 Intravenous catheter Orem theory Graded extended care SELF-EFFICACY
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海洋环境不等宽桥面预制50mT梁架设技术
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作者 王磊 《智能城市》 2025年第2期149-151,共3页
本文以青兰高速公路双埠至河套段改扩建工程中的女姑口特大桥为研究对象,聚焦于跨越海洋浅滩淤泥地质的桥面变宽段预制50 mT梁架设技术。针对变宽段位于泥滩区无法采用陆地起重机架设且盖梁长度受限的问题,提出在海滩中搭设临时支架的... 本文以青兰高速公路双埠至河套段改扩建工程中的女姑口特大桥为研究对象,聚焦于跨越海洋浅滩淤泥地质的桥面变宽段预制50 mT梁架设技术。针对变宽段位于泥滩区无法采用陆地起重机架设且盖梁长度受限的问题,提出在海滩中搭设临时支架的解决方案。通过分析淤泥地质对钢管柱承载力以及波浪力对钢管柱支架稳定性的影响因素,给出了相应的施工方法。基于常规架桥机架设T梁步序,提出变宽段T梁分阶段架设的优化方法,并通过数值模拟验证了其可靠性。结果表明,该方法有效提高了变宽段T梁架设的安全性和安装精度,为类似工程提供了参考。 展开更多
关键词 海洋环境 变宽段 50 mt 架设
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Efficacy of combined psychological and physical nursing in preventing peripherally inserted central catheter-related thrombosis in gastric cancer patients 被引量:1
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作者 Wei-Jing Ni Yu-Xiu Xi Yong-Chao Zhou 《World Journal of Gastrointestinal Surgery》 2025年第3期206-212,共7页
BACKGROUND Long-term chemotherapy for patients with gastric cancer(GC),facilitated by peripherally inserted central catheter(PICC)catheterization,reduces vascular damage and enhances drug delivery efficiency but carri... BACKGROUND Long-term chemotherapy for patients with gastric cancer(GC),facilitated by peripherally inserted central catheter(PICC)catheterization,reduces vascular damage and enhances drug delivery efficiency but carries risks of catheter-related complications.A combination of group psychological nursing and physical mo-vement care significantly mitigates the risk of venous thrombosis and improves psychological well-being,and enhances motor function,underscoring its clinical importance.AIM To assess group psychological and physical movement nursing in preventing venous thrombosis in patients with PICC GC.METHODS Sixty-five GC patients with PICC,admitted from January 2022 to January 2023,were randomly divided into two groups using the lottery method:A control group(n=35,routine nursing)and an observation group(n=30,routine nursing plus psychological nursing and physical movement nursing).Both groups re-ceived continuous care for 2 weeks.Pre-nursing and post-nursing data on psycho-logical state,physical function,chemotherapy-related thrombosis incidence,and cancer-related fatigue were analyzed using SPSS 26.0 and GraphPad Prism 8.0.RESULTS After nursing,both groups showed reduced Hamilton Anxiety Scale scores and increased General Perceived Self-Efficacy Scale scores,with the observation group performing better(P<0.05).The Functional Comprehensive Assessment score for the observation group after nursing was(65.42±2.35)points,lower than the control group’s(62.19±4.33)points(P<0.05).Although no significant difference was observed in the incidence of venous thrombosis between the two groups(χ2=0.815,P=0.367),the observation group had lower incidence.Both groups showed decreased Revised Piper Fatigue Scale scores,with the observation group scoring lower(P<0.05).CONCLUSION Group psychological and physical movement nursing for patients with PICC reduces venous thrombosis risk,improves psychological well-being,cancer-related fatigue,and physical function,making it highly promotable. 展开更多
关键词 Group psychological nursing Physical movement nursing Peripherally inserted central catheter Gastric cancer Venous thrombosis Cancer-related fatigue
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The Impact of Patient Education on the Nursing Care of Perioperative Patients in the Interventional Catheterization Room
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作者 Cui Yang Huan Xiong +1 位作者 Mao Li Yuanyuan Liu 《Journal of Clinical and Nursing Research》 2024年第1期19-24,共6页
Objective:To explore and analyze the effect of implementing a precise education model on the nursing care of perioperative patients in the interventional catheterization room.Methods:We selected 70 patients who were g... Objective:To explore and analyze the effect of implementing a precise education model on the nursing care of perioperative patients in the interventional catheterization room.Methods:We selected 70 patients who were going to undergo surgical intervention in our hospital from August 2020 to December 2022 as the subjects for this study through random sampling.The patients were divided into a control group and an observation group,with 35 cases in each group.The control group underwent basic nursing intervention,and the observation group was given precise patient education.The nursing effects of both groups were observed.Results:After the intervention,all compliance indicators of the observation group were better than those of the control group(P<0.05).Besides,the incidence of complications in the observation group(2.86%)was lower than that of the control group(17.14%)with P<0.05.Furthermore,the patient satisfaction of the observation group(97.14%)was higher than that of the control group(82.86%),with P<0.05.Conclusion:A precise propaganda and education model facilitates the nursing of perioperative patients in the interventional catheterization room.Therefore,this practice should be popularized. 展开更多
关键词 Patient education model Interventional catheterization room Perioperative period Nursing effect
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“CAT+MT+PE”模式下《沙丘2》电影字幕英汉翻译研究
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作者 张笑涵 郑忠耀 《今古文创》 2025年第21期113-115,共3页
随着信息技术的快速发展,计算机辅助翻译在翻译行业中的应用效能日益凸显。基于这一发展趋势,本研究拟从“CAT+MT+PE”的整合式翻译模式切入,以翻译硕士专业学位(MTI)研究生的翻译能力培养为研究对象,深入探讨该模式在文本翻译实践中的... 随着信息技术的快速发展,计算机辅助翻译在翻译行业中的应用效能日益凸显。基于这一发展趋势,本研究拟从“CAT+MT+PE”的整合式翻译模式切入,以翻译硕士专业学位(MTI)研究生的翻译能力培养为研究对象,深入探讨该模式在文本翻译实践中的应用效果及其对翻译能力发展的影响机制。研究主要聚焦于如何在该模式下处理字幕翻译的特殊性,并采用案例分析法,选取《沙丘2》中的字幕片段,探讨如何通过CAT技术优化术语管理、利用MT进行快速初译,并通过PE确保译文的准确性和流畅性。研究结论表明,该模式能够有效解决字幕翻译中的文化差异问题,并通过功能对等理论实现译文与原文的语用效果对等。 展开更多
关键词 CAT+mt+PE 计算机辅助翻译 字幕翻译
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小线框源TEM拟MT二维反演技术及超前地质预报应用
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作者 韩自强 万玛龙智 +4 位作者 李祥丰 杨永强 朱小明 雒成贤 唐立 《煤田地质与勘探》 北大核心 2025年第8期203-215,共13页
【目的】针对瞬变电磁法(transient electromagnetic method,TEM)超前地质预报多维反演计算效率低,难以实用化的瓶颈,提出一种基于时频转换的小线框源TEM拟大地电磁法(magnetotelluric,MT)二维反演技术。【方法】首先证明小线框源TEM晚... 【目的】针对瞬变电磁法(transient electromagnetic method,TEM)超前地质预报多维反演计算效率低,难以实用化的瓶颈,提出一种基于时频转换的小线框源TEM拟大地电磁法(magnetotelluric,MT)二维反演技术。【方法】首先证明小线框源TEM晚期视电阻率与MT卡尼亚视电阻率在超前地质预报常用参数下具有显著相似性;引入最佳时频转换系数(C_(TF))实现晚期视电阻率向卡尼亚视电阻率的快速转换,转换偏差最大平均值为3.7%,转换偏差整体较小;进而利用MT成熟的反演方法处理转换数据。【结果】(1)拟MT一维反演结果中,电阻率相对误差最大为6.14%,深度相对误差最大为5.73%,反演误差整体较小。(2)拟MT二维反演结果中,含水构造上方测线的反演结果能够确定含水构造的边界位置和真实深度,反演电阻率更接近含水构造的真实电阻率值;含水构造以外测线的反演结果能够反映出低阻含水构造的存在,但各具体反演参数与实际存在一定偏差。【结论】该方法在普通PC端计算耗时<20 min,提升了计算效率和预报精度,为TEM超前地质预报提供实用化二维反演新途径。 展开更多
关键词 瞬变电磁法(TEM) 小线框源 大地电磁法(mt) 超前地质预报 二维反演 时频转换 卡尼亚视电阻率
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Melatonin improves endometrial receptivity and embryo implantation via MT2/PI3K/LIF signaling pathway in sows 被引量:1
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作者 Xue Qin Menghao Yang +4 位作者 Yang Yu Xiaolin Wang Yi Zheng Rui Cai Weijun Pang 《Journal of Animal Science and Biotechnology》 2025年第2期631-652,共22页
Background Increased backfat thickness of sows in early gestation is negative to reproductive performance.Endometrial receptivity is an important determinant of reproductive success,but it is unclear whether the effec... Background Increased backfat thickness of sows in early gestation is negative to reproductive performance.Endometrial receptivity is an important determinant of reproductive success,but it is unclear whether the effect of sow backfat thickness on litter size is associated with endometrial receptivity and whether melatonin treatment may have benefits.The present study seeks to answer these questions through in vitro and in vivo investigations.Results Excessive lipid deposition and lower melatonin levels in the uterus are detrimental to endometrial receptivity and embryo implantation in high backfat thickness sows.In cells treated with melatonin,the MT2/PI3K/LIF axis played a role in reducing lipid accumulation in porcine endometrial epithelium cells and improved endometrial receptivity.Furthermore,we found a reduction of lipids in the uterus after eight weeks of intraperitoneal administration of melatonin to HFD mice.Notably,melatonin treatment caused a significant reduction in the deposition of endometrial collagen,an increase in the number of glands,and repair of the pinopode structure,ultimately improving endometrial receptivity,promoting embryo implantation,and increasing the number of litter size of mice.Conclusions Collectively,the finding reveals the harmful effects of high backfat thickness sows on embryo implantation and highlight the role of melatonin and the MT2/PI3K/LIF axis in improving endometrial receptivity by enhancing metabolism and reducing the levels of uterine lipids in obese animals. 展开更多
关键词 Backfat thickness Embryo implantation Endometrial receptivity MELATONIN mt2/PI3K/LIF SOW
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基于生信分析探索AS3MT在NaAsO_(2)染毒肝癌细胞中的作用
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作者 郝雅婷 项发艳 文卫华 《山西医科大学学报》 2025年第4期339-346,共8页
目的探讨砷酸盐甲基转移酶(AS3MT)对砷染毒的人肝癌细胞(HepG2)活力和凋亡的影响。方法通过TCGA、GTEx等数据库分析AS3MT在多种癌症患者正常组织和肿瘤组织中的表达水平,以及AS3MT在肝细胞肝癌(LIHC)患者中的表达水平与DNA甲基化位点、... 目的探讨砷酸盐甲基转移酶(AS3MT)对砷染毒的人肝癌细胞(HepG2)活力和凋亡的影响。方法通过TCGA、GTEx等数据库分析AS3MT在多种癌症患者正常组织和肿瘤组织中的表达水平,以及AS3MT在肝细胞肝癌(LIHC)患者中的表达水平与DNA甲基化位点、免疫细胞浸润的相关性,及其在肝癌中的预后价值。HepG2细胞分别用0,8,16,24μmol/L NaAsO_(2)染毒后,RT-qPCR检测AS3MT在细胞中的表达;采用siRNA技术分别转染HepG2细胞,之后合并砷染毒,分别命名为NC组、siAS3MT#1组、siAS3MT#2组,siAS3MT#1+24μmol/L NaAsO_(2)染毒组、siAS3MT#2+24μmol/L NaAsO_(2)染毒组,RT-qPCR检测AS3MT转染效率,采用MTT、Hoechst 33342和碘化丙啶(HO/PI)染色实验检测HepG2细胞活力及凋亡情况。结果数据库分析结果显示,AS3MT在27种肿瘤组织和正常组织中的表达存在统计学差异(P<0.05);其中,AS3MT在LIHC中表达显著上调(t=0.578,P=0.007)。在LIHC患者中AS3MT表达与多个DNA甲基化位点显著相关(P<0.05);生存分析显示,AS3MT低表达组LIHC患者总体生存率显著高于高表达组(HR=0.63,P=0.009);且AS3MT表达是LIHC患者的独立预后因素(P=0.009);此外,AS3MT的表达水平与多种免疫细胞浸润水平相关(P<0.05)。与0μmol/L NaAsO_(2)比较,16,24μmol/L NaAsO_(2)染毒HepG2后AS3MT表达水平均升高(P<0.01)。与NC组比较,siAS3MT#1组和siAS3MT#2组HepG2细胞活力下降(P<0.05),凋亡增加。与转染siAS3MT#1或siAS3MT#2比较,合并24μmol/L NaAsO_(2)染毒后HepG2细胞活力进一步下降(P<0.01),且凋亡增加。结论AS3MT在砷染毒处理的HepG2细胞中呈现显著高表达。特异性沉默AS3MT可显著抑制砷染毒HepG2细胞的活力,并诱导细胞凋亡,提示AS3MT具有作为肝细胞肝癌潜在生物标志物及治疗靶点的应用前景。 展开更多
关键词 亚砷酸钠 AS3mt 肝癌 HEPG2细胞 生物信息学 免疫功能 泛癌
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二氧化碳甲烷化催化剂 Ni@MTS-9合成表征及性能评价 被引量:1
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作者 刘云凤 郭晓文 华德润 《赣南师范大学学报》 2025年第3期129-134,共6页
通过模板法合成核壳结构的Ni@MTS-9催化剂,并将该催化剂用于二氧化碳甲烷重整反应,评价其催化性能.通过透射电镜、氮气吸附脱附、X射线衍射和电子衍射等表征技术研究催化剂结构.结果表明复合材料的壳能显著提高催化剂的性能,核壳结构的... 通过模板法合成核壳结构的Ni@MTS-9催化剂,并将该催化剂用于二氧化碳甲烷重整反应,评价其催化性能.通过透射电镜、氮气吸附脱附、X射线衍射和电子衍射等表征技术研究催化剂结构.结果表明复合材料的壳能显著提高催化剂的性能,核壳结构的催化剂能有效抑制纳米镍颗粒的团聚,从而提高催化剂寿命. 展开更多
关键词 甲烷重整 催化剂 Ni@mtS-9
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