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Anthraquinones of Cassiae Semen alleviate lipid accumulation in obesity by regulating brown adipose tissue and liver function
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作者 Yijie Li Ruiyu Wu +5 位作者 Xin Li Jianan Li Yinhao Zhang Yanbo Huang Guifang Fan Xiaojiaoyang Li 《Chinese Herbal Medicines》 2025年第3期488-499,共12页
Objective:Cassiae Semen(CS,Juemingzi in Chinese)is a widely used traditional Chinese medicine with a variety of pharmacological effects.This study aimed to investigate the potential therapeutic effects and molecular m... Objective:Cassiae Semen(CS,Juemingzi in Chinese)is a widely used traditional Chinese medicine with a variety of pharmacological effects.This study aimed to investigate the potential therapeutic effects and molecular mechanisms of anthraquinones of CS(AQS)for adiposity.Methods:The chemical components of the AQS were determined using high-performance liquid chromatography(HPLC).Network pharmacology analysis was used to predict potential anti-obesity targets of action for AQS.We constructed high fat with high sugar water diet-induced obese mice and observed their body weight and whole-body lipid metabolism to evaluate the efficacy of AQS in promoting lipid metabolism.Subsequently,the epidermal temperature at the brown adipose tissue(BAT)before and after cold stimulation was observed and the expression of lipid metabolism-related genes in the liver and BAT tissues was detected to clarify the mechanism of action of AQS.Results:Network pharmacology analysis showed that AQS was involved in the regulation of liver and adipose tissue function under obesity.Pathological and biochemical results showed that AQS reduced lipid accumulation in the liver and adipose tissue induced by an unhealthy diet.With the increase of cold tolerance,the volume and weight of BAT were increased by AQS,suggesting that it regulated the body heat production dominated by BAT.After AQS treatment,the levels of genes related to uncoupling protein1(UCP1)-mediated adaptive thermogenesis in BAT tissues and lipid metabolism in the liver were also increased,which further proved that AQS activated BAT function to promote lipid metabolism in the whole body.Conclusion:This study revealed the pharmacological effects of AQS,thereby providing a scientific basis for regulating BAT thermogenesis and liver lipid metabolism to alleviate obesity and providing clues for further exploring the application of natural active ingredients in the treatment of metabolismrelated diseases. 展开更多
关键词 ADIPOSITY ANTHRAQUINONES brown adipose tissue cassiae Semen liver lipid metabolism THERMOGENESIS
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Cassiae Semen improves non-alcoholic fatty liver disease through autophagy-related pathway 被引量:8
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作者 Mingning Ding Fei Zhou +6 位作者 Yijie Li Chuanyang Liu Yiqing Gu Jianzhi Wu Guifang Fan Yajing Li Xiaojiaoyang Li 《Chinese Herbal Medicines》 CAS 2023年第3期421-429,共9页
Objective:Cassiae Semen(CS,Juemingzi in Chinese)has been used for thousands of years in ancient Chinese history for relieving constipation,improving liver function as well as preventing myopia.Here we aimed to elucida... Objective:Cassiae Semen(CS,Juemingzi in Chinese)has been used for thousands of years in ancient Chinese history for relieving constipation,improving liver function as well as preventing myopia.Here we aimed to elucidate the anti-steatosis effect and underlying mechanism of CS against non-alcoholic fatty liver disease(NAFLD).Methods:High-performance liquid chromatography(HPLC)was used to identify the major components of CS water extract.Mice were fed with a high-fat and sugar-water(HFSW)diet to induce hepatic steatosis and then treated with CS.The anti-NAFLD effect was determined by measuring serum biomarkers and histopathology staining.Additionally,the effects of CS on cell viability and lipid metabolism in oleic acid and palmitic acid(OAPA)-treated HepG2 cells were measured.The expression of essential genes and proteins involved in lipid metabolism and autophagy signalings were measured to uncover the underlying mechanism.Results:Five compounds,including aurantio-obtusin,rubrofusarin gentiobioside,cassiaside C,emodin and rhein were simultaneously identified in CS extract.CS not only improved the diet-induced hepatic steatosis in vivo,as indicated by decreased number and size of lipid droplets,hepatic and serum triglycerides(TG)levels,but also markedly attenuated the OAPA-induced lipid accumulation in hepatocytes.These lipid-lowering effects induced by CS were largely dependent on the inhibition of fatty acid synthase(FASN)and the activation of autophagy-related signaling,including AMP-activated protein kinase(AMPK),light chain 3-II(LC3-II)/LC3-1 and autophagy-related gene5(ATG5).Conclusion:Our study suggested that CS effectively protected liver steatosis via decreasing FASN-related fatty acid synthesis and activating AMPK-mediated autophagy,which might become a promising therapeutic strategy for relieving NAFLD. 展开更多
关键词 AUTOPHAGY AMPK Cassia obtusifolia L. Cassia tora L. cassiae Semenfatty acid synthesis non-alcoholic fatty acid disease
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Typical blood parameters and gut microbiota alterations associated with the mutual conversion of cold and hot patterns induced by Chinese herbal medicines
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作者 Yanan Yang Yuxiao Li +2 位作者 Kebin Wang Shengxian Wu Chongming Wu 《Journal of Traditional Chinese Medical Sciences》 2026年第1期34-47,共14页
Objective:To elucidate the quantification and standardization of cold and hot patterns,the fundamental concepts in traditional Chinese medicine(TCM).Methods:This randomized cross-controlled trial recruited 30 healthy ... Objective:To elucidate the quantification and standardization of cold and hot patterns,the fundamental concepts in traditional Chinese medicine(TCM).Methods:This randomized cross-controlled trial recruited 30 healthy volunteers.Participants in Group 1 underwent 14 days of Coptis chinensis Franch.(C.chinensis,Huang Lian)treatment to shift their body toward the cold pattern,followed by 7 days of washout and 14 days of Cinnamomum cassia Presl(C.cassia,Rou Gui)treatment to shift their body toward the hot pattern.Participants in Group 2 underwent the opposite treatment.Blood and stool samples were collected for routine blood testing and full-length 16S rRNA metagenomic sequencing.Results:Red blood cells(RBC),hemoglobin(HGB),hematocrit(HCT),and blood platelet count(BPC)were increased by C.chinensis,whereas the mean corpuscular HGB concentration(MCHC)was increased by C.cassia.RBC,HGB,HCT,and BPC were positively associated with the cold pattern but negatively correlated with the hot pattern,whereas MCHC showed opposite relationships.C.chinensis-increased Blautia stercoris was positively correlated with RBC,HGB,and HCT under C.chinensis treatment,whereas C.cassia-enhanced Parabacteroides distasonis_A was positively associated with MCHC under C.cassia treatment.Interestingly,five indicators(RBC,HGB,HCT,Blautia stercoris,and Prevotella copri)had an area under the curve of 0.795 for predicting the cold pattern.Although three indicators(MCHC,Akkermansia sp004167605,and Parabacteroides distasonis_A)showed poor predictive ability for the hot pattern,when the individual’s gut microbiota experienced disturbance by cold Chinese materia medica stimulation,the predictive ability increased to 0.703.Conclusion:This study suggests that blood parameters and gut microbes may be potential indicators of hot and cold TCM patterns,which could benefit the objectivity and scientific rigor of TCM. 展开更多
关键词 Traditional Chinese medicine Pattern differentiation Gut microbiota Coptis chinensis Franch Cinnamomum cassia Presl
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Sustainable Dyeing of Polyamide 6 Fabrics Using Waste Pods of Cassia fistula as a Novel Source of Natural Colourants
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作者 Tanawat Ruangteprat Somchai Udon +5 位作者 Jaruwan Diswat Jaratpim Wangyen Rattanaphol Mongkholrattanasit Hathaitip Srichompoo Jiramet Suparat Krailerck Visesphan 《Journal of Environmental & Earth Sciences》 2025年第9期76-88,共13页
Environmental concerns over synthetic dyes,including water pollution and high energy demands,have driven interest in sustainable alternatives.This research investigates the colouration of polyamide 6(nylon 6)textiles ... Environmental concerns over synthetic dyes,including water pollution and high energy demands,have driven interest in sustainable alternatives.This research investigates the colouration of polyamide 6(nylon 6)textiles using a natural dye derived from the mature pods of Cassia fistula,which serve as a source of anthraquinone-based pigments.The study systematically evaluated the influence of dyeing parameters-namely temperature(30-90℃),duration(10-60 min),pH range(4-11),dye concentration(10%-70%owf),and post-mordanting using alum,ferrous sulfate,and stannous chloride-on the resulting colour strength(K/S)and CIE Lab*coordinates.The fastness characteristics of polyamide 6 fabric were assessed,with the corresponding results detailed in the subsequent sections.Maximum dye absorption was achieved at 90℃for 60 minutes under acidic conditions(pH 4),and from the conditions was given K/S 2.242.An increase in dye concentration led to higher K/S values,which were further augmented by mordanting,with aluminum potassium sulfate and stannous chloride yielding the greatest results.Colour fastness assessments indicated good to excellent resistance to washing,water exposure,rubbing,and perspiration,all of the properties were up to 4.Whereas resistance to light was found from 1 to 2.The findings confirm Cassia fistula extract as a renewable,eco-friendly dye for polyamide 6,offering commercially viable colour strength and fastness while supporting sustainable textile processing. 展开更多
关键词 Natural Dye Cassia Fistula Waste POLYAMIDE MORDANT
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几种植物生长调节剂对决明种子萌发及幼苗生长的影响 被引量:25
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作者 朱霞 胡勇 +1 位作者 王晓丽 陈诗 《作物杂志》 CAS CSCD 北大核心 2010年第1期46-48,共3页
分别采用GA3、6-BA和NAA处理决明(Cassia obtusifolia L.)种子,结果表明:GA3、6-BA、NAA可提高种子发芽率、发芽势和活力指数,还可增加幼苗的根数、全株鲜重和干重,三种植物生长调节剂都能够调节决明幼苗的生长发育,其中100mg/L对决明... 分别采用GA3、6-BA和NAA处理决明(Cassia obtusifolia L.)种子,结果表明:GA3、6-BA、NAA可提高种子发芽率、发芽势和活力指数,还可增加幼苗的根数、全株鲜重和干重,三种植物生长调节剂都能够调节决明幼苗的生长发育,其中100mg/L对决明种子发芽和幼苗生长的作用效果最好。 展开更多
关键词 植物生长调节剂 决明(Cassia obtusi-folia L.) 种子活力 幼苗生长
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款冬花和决明子中挥发性成分及抗氧化性质研究 被引量:4
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作者 何保江 屈展 +2 位作者 曾世通 霍现宽 张文娟 《中国酿造》 CAS 2014年第1期81-85,共5页
对款冬花和决明子中挥发性成分和抗氧化活性进行研究。采用水蒸气蒸馏法提取得到挥发性成分,利用GC-MS对其成分进行分析。用可见分光光度法测定挥发性成分对1,1-二苯基-2-三硝基苯肼(DPPH)自由基清除能力、ABTS自由基的清除能力以及FRA... 对款冬花和决明子中挥发性成分和抗氧化活性进行研究。采用水蒸气蒸馏法提取得到挥发性成分,利用GC-MS对其成分进行分析。用可见分光光度法测定挥发性成分对1,1-二苯基-2-三硝基苯肼(DPPH)自由基清除能力、ABTS自由基的清除能力以及FRAP能力。结果表明,款冬花和决明子中的挥发性成分对羟基自由基具有不同的清除能力,且不同中药挥发性成分中高含量的总多酚和总黄酮可能是其抗氧化活性的主要物质来源。中药挥发性成分具有较好的抗氧化效果,能够作为天然抗氧化剂应用于食品和烟草工业。 展开更多
关键词 款冬花 决明子 挥发性物质 气质联用 自由基清除能力 CASSIA obtusigolia L
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Comparison and Quality Assessment of Cassia Bark (Cortex Cinnamomi) by Thin Layer Chromatography 被引量:2
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作者 贺震旦 乔春峰 +7 位作者 韩全斌 宋景政 郑全能 徐宏喜 江仁望 黄家乐 毕培曦 邵鹏柱 《Journal of Chinese Pharmaceutical Sciences》 CAS 2006年第4期195-199,共5页
Aim To differentiate the genuine cassia bark from its substitutes and adulterants. Methods Six components, phenylpropyl acetate, cinnamyl acetate, cinnamaldehyde, cinnamyl alcohol, coumarin, and cinnamic acid were use... Aim To differentiate the genuine cassia bark from its substitutes and adulterants. Methods Six components, phenylpropyl acetate, cinnamyl acetate, cinnamaldehyde, cinnamyl alcohol, coumarin, and cinnamic acid were used as characteristic markers, and an optimized TLC method was developed. Results The TLC profile of cassia bark is similar to its closely related variety Cinnamomum cassia Presl var. macrophyllum Chu but significantly different from other six Cinnamomum species. High content of phenylpropyl acet... 展开更多
关键词 Cortex Cinnamomi Cinnamomum cassia TLC CINNAMALDEHYDE chemical profile
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Determination of Emodin and Chrysophanol Contents in Callus of Cassia tora L. Leaf 被引量:1
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作者 周嘉裕 廖海 +3 位作者 李利平 刘乐 贺葵邦 马丽 《Agricultural Science & Technology》 CAS 2008年第2期60-62,共3页
[ Objective] Through inductive culture, emodin and chrysophanol contents in cassia seed were increased. [ Method ] MS culture medium was used to bourgeon seedlings of cassia seed and to induce cotyledon callus of cass... [ Objective] Through inductive culture, emodin and chrysophanol contents in cassia seed were increased. [ Method ] MS culture medium was used to bourgeon seedlings of cassia seed and to induce cotyledon callus of cassia seed while HPLC method was adopted to determine emodin and ehrysophanol eontents.[ Result] Emedin and chrysophanol contents in cotyledon callus were 0. 099% and 0. 312%, respectively, while they were 0.029% and 0. 190% respectively in cassia seed. [ Conclusion] The method of inducing cotyledon callus was helpful for increasing emodin coment in cassia seed. 展开更多
关键词 Cassia seed CALLUS ANTHRAQUINONE HPLC
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大黄素等有效成分的分离纯化和谱学表征
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作者 郎中敏 洪海龙 +2 位作者 韩利民 竺宁 索全伶 《中国食品添加剂》 CAS 北大核心 2011年第6期71-74,共4页
随着绿色食品的兴起,人们对天然色素的需求量越来越大,因此,从天然产物中提取具有药用功能的无毒无害的食用色素,是当今食用色素发展的新趋势。决明子为豆科植物决明的干燥成熟种子,含有很多药用有效成分。本文采用有机溶剂萃取法和沉淀... 随着绿色食品的兴起,人们对天然色素的需求量越来越大,因此,从天然产物中提取具有药用功能的无毒无害的食用色素,是当今食用色素发展的新趋势。决明子为豆科植物决明的干燥成熟种子,含有很多药用有效成分。本文采用有机溶剂萃取法和沉淀法,从决明子中提取出三种主要有效成分粗品,通过柱层析和重结晶技术对有效成分粗品进行了分离和纯化,得到了三种决明子色素(Ⅰ、Ⅱ、Ⅲ)。利用蒽醌类化合物的显色反应及FTIR,UV-Vis,MS,1H,13CNMR等分析测试手段,对三种化合物进行了表征,确定了它们的分子组成和结构。鉴定出化合物Ⅰ为1,8-二羟基3-甲基6-甲氧基蒽醌(大黄素甲醚);化合物Ⅱ为1,8-二羟基3-甲基蒽醌(大黄酚);化合物Ⅲ为1,6,8-三羟基3-甲基蒽醌(大黄素)。 展开更多
关键词 CASSIA SEED EMODIN natural food PIGMENT anthraqinone DERIVATIVE spectra characterization
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肉桂、石韦内生真菌的分离纯化及抑菌性研究 被引量:1
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作者 李涛 李小清 +2 位作者 李燕 郭秋月 刘俊林 《食品安全导刊》 2015年第11X期132-134,共3页
采用组织块分离法从肉桂(Cinnamomum cassia Pres1)、石韦(Pyrrosia lingua(Thunb)Farwell)组织中分别分离得到7、24株内生真菌,以大肠杆菌(Escherichia coli)、肺炎球菌(diplococcus pneumoniae)、金黄色葡萄球菌(Staphylococcus aure... 采用组织块分离法从肉桂(Cinnamomum cassia Pres1)、石韦(Pyrrosia lingua(Thunb)Farwell)组织中分别分离得到7、24株内生真菌,以大肠杆菌(Escherichia coli)、肺炎球菌(diplococcus pneumoniae)、金黄色葡萄球菌(Staphylococcus aureus)为供试菌种。 展开更多
关键词 内生真菌 石韦 金黄色葡萄球菌 供试菌种 肺炎球菌 CINNAMOMUM CASSIA 抑制作用
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水杨酸调节决明根系铝诱导的氧化胁迫 被引量:4
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作者 王猷生 汪瑾 +6 位作者 杨志敏 王庆亚 吕波 李少琼 卢亚萍 王松华 孙新 《Acta Botanica Sinica》 CSCD 2004年第7期819-828,共10页
水杨酸(Salicylic acid,SA)在调节生物和非生物胁迫,诱导植物氧化胁迫中起着重要的作用,但对铝诱导的氧化胁迫的调节作用尚不清楚。本文研究了SA对决明(Cassiatora L.)根系铝诱导的H2O2和O2ˉ含量变化,包括抗氧化酶活性以及细胞质... 水杨酸(Salicylic acid,SA)在调节生物和非生物胁迫,诱导植物氧化胁迫中起着重要的作用,但对铝诱导的氧化胁迫的调节作用尚不清楚。本文研究了SA对决明(Cassiatora L.)根系铝诱导的H2O2和O2ˉ含量变化,包括抗氧化酶活性以及细胞质膜过氧化胁迫变化的影响。介质中20μmol/L铝处理增加质膜透性,导致MDA含量上升及根尖细胞Evans blue染色加重(测定细胞死亡),而外源供给5μmol/LSA能缓解铝诱导的氧化胁迫。SA处理能明显降低根尖H2O2和O2ˉ的含量,但两者含量与CAT、APX和GR的活性变化没有相关性,而与POD活性增加有关。水杨酸诱导H2O2含量的下降与抑制O2ˉ积累和SOD活性有关。结果表明,SA可能激活一条由H2O2介导的、依赖于POD的抗氧化机制来缓解脂质的过氧化作用。 展开更多
关键词 水杨酸 铝毒 氧化胁迫 过氧化氢 决明(Cassia tora)
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肉桂加工剩余物木屑对赤芝生长的影响 被引量:1
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作者 湛年勇 陆荣生 +4 位作者 邓莉杰 唐璇 韩美丽 陆泰榕 陈进宁 《湖北农业科学》 2020年第16期91-95,共5页
以肉桂(Cinnamomum cassia Presl)加工桂皮后的剩余物木屑为原料,研究其对赤芝(Ganoderma lucidum)生长的影响。结果表明,赤芝生长不同阶段培养基中添加肉桂加工剩余物木屑对赤芝生长具有一定的促进作用。其中,母种培养基中添加肉桂加... 以肉桂(Cinnamomum cassia Presl)加工桂皮后的剩余物木屑为原料,研究其对赤芝(Ganoderma lucidum)生长的影响。结果表明,赤芝生长不同阶段培养基中添加肉桂加工剩余物木屑对赤芝生长具有一定的促进作用。其中,母种培养基中添加肉桂加工剩余物木屑75~150 g/L,菌丝生长速度可达8.2~8.4 mm/d,菌种贮藏时间可延长至9个月;原种、栽培种培养基中分别添加200~300 g/kg、300~500 g/kg的肉桂加工剩余物木屑,菌丝生长速度分别达8.4、9.3 mm/d,明显高于对照。出芝袋中添加肉桂加工剩余物木屑450~600 g/kg、泥碳土75~100 g/kg,可使生物学转化率提高到66%~72%。 展开更多
关键词 肉桂(Cinnamomum cassia Presl)树 木屑 赤芝(Ganoderma lucidum) 生长
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ICP-MS/ICP-AES法测定决明子中无机元素的含量 被引量:1
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作者 刘辉庭 陈少东 王力前 《湖北农业科学》 北大核心 2012年第24期5766-5768,共3页
采用ICP-AES法测定决明子(Cassia obtusifolia L.)中Na、Mg、P、Ca、Ti、Zn、Mn、Fe、K、Sr、B、Al、Ba,采用ICP-MS法测定Li、Be、Tl、Mo、Pb、Cd、Co、V、Cr、Cu、Ni。结果表明,决明子中富含K、Ca、P、Mg、Al、Fe、Na,而Be、Cd、Tl、P... 采用ICP-AES法测定决明子(Cassia obtusifolia L.)中Na、Mg、P、Ca、Ti、Zn、Mn、Fe、K、Sr、B、Al、Ba,采用ICP-MS法测定Li、Be、Tl、Mo、Pb、Cd、Co、V、Cr、Cu、Ni。结果表明,决明子中富含K、Ca、P、Mg、Al、Fe、Na,而Be、Cd、Tl、Pb等元素含量极微,不足0.02μg/g。在所测定的24种元素中,含量顺序依次为K>Ca>P>Mg>Al>Fe>Na>Zn>Sr>B>Mn>Ba>Cu>Ti>Cr>Ni>Mo>Co>V>Li>Cd>Pb>Tl>Be。 展开更多
关键词 决明子(Cassia obtusifolia L.) ICP-MS ICP-AES 元素
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不同土壤基质对花旗木种子发芽率的影响 被引量:2
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作者 符溶 陈润泽 +3 位作者 陈国德 符生波 杜尚嘉 钟圣赟 《林业科技通讯》 2021年第1期77-80,共4页
为探索花旗木(Cassia bakeriana Craib)种子育苗的较佳土壤基质,以在海南省东方市采集的花旗木种子为试验材料,开展不同土壤基质对花旗木种子发芽的影响研究。结果表明,处理组4(黄土∶沙土=2∶1)发芽率较高,为81.67%。而在苗木生长方面... 为探索花旗木(Cassia bakeriana Craib)种子育苗的较佳土壤基质,以在海南省东方市采集的花旗木种子为试验材料,开展不同土壤基质对花旗木种子发芽的影响研究。结果表明,处理组4(黄土∶沙土=2∶1)发芽率较高,为81.67%。而在苗木生长方面,以处理组1(腐殖质土)表现较好,株高为37.40 cm,地径为3.63 cm。综合发芽率和成苗率方面考虑,建议用黄土∶沙土=2∶1作育苗基质,成苗后可对其基质更换为腐殖质土,并加强苗期管理,以获得较好的成苗效果。 展开更多
关键词 花旗木 Cassia bakeriana Craib 种子育苗 基质 发芽率
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A New Anthranquinone Glycoside from the Seeds of Cassia obtusifolia 被引量:12
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作者 ChuHuaLI XiaoYiWEI +2 位作者 XuELI PingWU BaoJiangGUO 《Chinese Chemical Letters》 SCIE CAS CSCD 2004年第12期1448-1450,共3页
A new anthraquinone glycoside, emodin-1-O-β-gentiobioside 1, together with threeknown compounds, chrysophanol-1-O-β-gentiobioside 2, physcion-8-O-β-gentiobioside 3, andchrysophanol-1-O-β-D-glucopyranosyl-(1→3)-β... A new anthraquinone glycoside, emodin-1-O-β-gentiobioside 1, together with threeknown compounds, chrysophanol-1-O-β-gentiobioside 2, physcion-8-O-β-gentiobioside 3, andchrysophanol-1-O-β-D-glucopyranosyl-(1→3)-β-D-glucopyranosyl-(1→6)-β-D-glucopyranoside4 was isolated from the seeds of Cassia obtusifolia. Its structure was elucidated on the basis ofspectroscopic evidence. 展开更多
关键词 Cassia obtusifolia LEGUMINOSAE anthraqinone glycosides emodin-1-Oβ-gentiobioside.
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Antioxidant, hepatoprotective and hypolipidemic effects of methanolic root extract of Cassia singueana in rats following acute and chronic carbon tetrachloride intoxication 被引量:5
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作者 Ottu OJ Atawodi SE Onyike E 《Asian Pacific Journal of Tropical Medicine》 SCIE CAS 2013年第8期609-615,共7页
Objective: To evaluate in vivo antioxidant and hepatoprotective activities of the methanolic extract of the root of Cassia singueana in rats following acute and chronic carbon tetrachloride intoxication. Methods: Malo... Objective: To evaluate in vivo antioxidant and hepatoprotective activities of the methanolic extract of the root of Cassia singueana in rats following acute and chronic carbon tetrachloride intoxication. Methods: Malondialdehyde (MDA), aspartate aminotransferase (AST), alanine aminotransferase (ALT) and bilirubin as indices of liver damage and lipid peroxidation were detected in rats after intraperitoneal administration of extract (5 mg/kg). Results: The liver, kidney and heart showed significant reduction ( P <0.05) in the levels of MDA from (0.18依0.04), (0.23 依0.07) and (0.26依0.10) nmol/mg respectively in the CCl 4 control to (0.15依0.03), (0.17依0.04) and (0.17 依0.07) nmol/mg protein in groups pre-treated with the extract for three days at 5 mg/kg). Similarly, compared to the CCl 4 control, significant reduction ( P<0.05) in serum AST, ALT and bilirubin as well as in level of total cholesterol and MDA with concomitant increase in HDL cholesterol, superoxide dismutase and catalase levels when CCl 4 -intoxicated rats were treated with Cassia singueana root extract for two weeks. Conclusions: These results suggest that methanolic extract of Cassia singueana contain potent antioxidant compounds that can offer significant protection against hepatic and oxidative injuries. 展开更多
关键词 ANTIOXIDANT EFFECT HEPATOPROTECTIVE EFFECT Disease chemoprevention Medicinal plant Oxidative stress CASSIA singueana
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YISHOU JIANGZHI (DE-BLOOD-LIPID) TABLETS IN THE TREATMENT OF HYPERLIPEMIA 被引量:4
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作者 关颖明 赵淑芬 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 1995年第3期178-179,共2页
The Yishoujiangzhi (de-blood-lipid) tablets (composed of Radix Polygori Multiflori, Rhizoma Polygonati, Fructus Lycii, Crataegus Pinnatifida and Cassia Tora) were used in the treatment of 130 cases of hyperlipemia, ac... The Yishoujiangzhi (de-blood-lipid) tablets (composed of Radix Polygori Multiflori, Rhizoma Polygonati, Fructus Lycii, Crataegus Pinnatifida and Cassia Tora) were used in the treatment of 130 cases of hyperlipemia, achieving an effective rate of 87.0% in lowering serum cholesterol and 80.8% in lowering triglyceride. 展开更多
关键词 lowering Radix CRATAEGUS triglyceride TABLETS cholesterol LIPID CASSIA markedly DISCOMFORT
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Two new glycosides from the genus of Cassia 被引量:4
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作者 Zhu Ju Wang Qiu Ping Wu +4 位作者 Li Ying Tang Mei Hong Fu Yan He Qian Feng Gong Lu Qi Huang 《Chinese Chemical Letters》 SCIE CAS CSCD 2007年第10期1218-1220,共3页
Two new glycosides were isolated and characterized by spectral analysis from the seeds of Cassia obtusifolia and the leaves of Cassia angustifolia. The structure was elucidated as 1-hydroxyl-2-acetyl-3,8-dimethoxynaph... Two new glycosides were isolated and characterized by spectral analysis from the seeds of Cassia obtusifolia and the leaves of Cassia angustifolia. The structure was elucidated as 1-hydroxyl-2-acetyl-3,8-dimethoxynaphthalene-6-O-β-D-apiofuranosyl- (1→2)-β-D-glucopyranoside and 2-acetyl-3-methyl-8-methoxyl-1,4-naphthoquinone-6-O-β-D-glucopyranoside. 展开更多
关键词 Cassia obtusifolia Cassia angustifolia Naphthalene glycoside Naphthoquinone glucoside
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Authentication of Cassia seeds on the basis of two-wavelength HPLC fingerprinting with the use of chemometrics 被引量:5
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作者 Serge Kokot 《Chinese Chemical Letters》 SCIE CAS CSCD 2010年第2期213-216,共4页
High performance liquid chromatographic(HPLC) fingerprints of Cassia seed,a traditional Chinese medicine(TCM),were developed by means of the chromatograms at two wavelengths of 238 and 282 nm.Then,the two data sets we... High performance liquid chromatographic(HPLC) fingerprints of Cassia seed,a traditional Chinese medicine(TCM),were developed by means of the chromatograms at two wavelengths of 238 and 282 nm.Then,the two data sets were combined into one matrix.The application of principal component analysis(PCA) for this data matrix showed that the samples were clustered into four groups in accordance with the plant sources and preparation procedures.Furthermore,partial least squares(PLS),back propagation artificial neural... 展开更多
关键词 Two-wavelength HPLC fingerprinting Cassia seeds CHEMOMETRICS AUTHENTICATION
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The essential oil components of Cinnamomum cassia: an analysis under different thinning models of plantation Pinus massoniana 被引量:4
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作者 Dayan Tao Yuanfa Li +3 位作者 Daodiao Lu Yehong Luo Sufang Yu Shaoming Ye 《Journal of Forestry Research》 SCIE CAS CSCD 2016年第3期707-717,共11页
Thinning is an important activity employed in forest management. To date, studies have mainly focused on the effects of thinning on the growth of trees during the same thinning period. In this study, plantation Pinus ... Thinning is an important activity employed in forest management. To date, studies have mainly focused on the effects of thinning on the growth of trees during the same thinning period. In this study, plantation Pinus massoniana Lamb. near maturity were thinned at varying intensities and an economically important species, Cinnamomum cassia Presl., was planted beneath the thinned canopy. The aim of the study was to explore the effects of the extent of thinning on the essential oil content and its components of C. cassia in different parts of the plant, as well as the economic feasibility of the P. massoniana-C.cassia management model. Thinning significantly reduced the oil yield in the bark and branches of C. cassia, but hardly impacted the oil yield from C. cassia leaves compared with pure C. cassia forest(CK). Among the different thinning treatments, both light(T.4) and extensive(T.1)thinning reduced the oil yield of C. cassia bark and new branches. The concentrations of the main aldehydes differed in different parts of the plant and were affected by the extent of thinning. The influence on cinnamaldehyde in the bark was minor, but was much greater in the branches and leaves. Both the oil yield and content of cinnamaldehyde showed that moderate(T.3) thinning was more favorable than other thinning models. These results not only provide a potentially promising model for the transformation of low-yield artificial pure forests of P. massoniana in the future, but also offer a reference for the management of artificial mixed stands. 展开更多
关键词 THINNING Pinus massoniana Lamb. Cinnamomum cassia Presl Essential oils PLANTATION
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