The enzymatic synthesis of a tetrapeptide Phac-Met-Gly-Trp-Met-OEt, a fragment of the cholecystokinin C-terminal octapeptide CCK-8, was reported This fragment was synthesized by coupling Phac-Met-OEt with Gly-OMe, T...The enzymatic synthesis of a tetrapeptide Phac-Met-Gly-Trp-Met-OEt, a fragment of the cholecystokinin C-terminal octapeptide CCK-8, was reported This fragment was synthesized by coupling Phac-Met-OEt with Gly-OMe, Trp-OMe and Met-OEt successively These three steps were catalyzed by α-chymotrpsin, Papain and α-chymotrpsin respectively The results of FAB-MS showed that all the products had the correct molecular mass展开更多
This article aims to enhance seismic hazard assessment methods for Kazakhstan’s seismotectonic conditions.It combines probabilistic seismic hazard analysis(PSHA),ground motion simulation,sitespecific geological and g...This article aims to enhance seismic hazard assessment methods for Kazakhstan’s seismotectonic conditions.It combines probabilistic seismic hazard analysis(PSHA),ground motion simulation,sitespecific geological and geotechnical data analysis,and seismic scenario analysis to develop Probabilistic General Seismic Zoning(GSZ)maps for Kazakhstan and Probabilistic Seismic Microzoning maps for Almaty.These maps align with Eurocode 8 principles,incorporating seismic intensity and engineering parameters like peak ground acceleration(PGA).The new procedure,applied in national projects,has resulted in GSZ maps for the country,seismic microzoning maps for Almaty,and detailed seismic zoning maps for East Kazakhstan.These maps,part of a regulatory document,guide earthquake-resistant design and construction.They offer a comprehensive assessment of seismic hazards,integrating traditional Medvedev-Sponheuer-Karnik(MSK-64)intensity scale points with quantitative parameters like peak ground acceleration.This innovative approach promises to advance methods for quantifying seismic hazards in specific regions.展开更多
文摘The enzymatic synthesis of a tetrapeptide Phac-Met-Gly-Trp-Met-OEt, a fragment of the cholecystokinin C-terminal octapeptide CCK-8, was reported This fragment was synthesized by coupling Phac-Met-OEt with Gly-OMe, Trp-OMe and Met-OEt successively These three steps were catalyzed by α-chymotrpsin, Papain and α-chymotrpsin respectively The results of FAB-MS showed that all the products had the correct molecular mass
基金The work was carried out in the framework of earmarked funding“Assessment of seismic hazard of territories of Kazakhstan on modern scientific and methodological basis”,programme code number F.0980.Source of funding-Ministry of Science and Higher Education of the Republic of Kazakhstan.
文摘This article aims to enhance seismic hazard assessment methods for Kazakhstan’s seismotectonic conditions.It combines probabilistic seismic hazard analysis(PSHA),ground motion simulation,sitespecific geological and geotechnical data analysis,and seismic scenario analysis to develop Probabilistic General Seismic Zoning(GSZ)maps for Kazakhstan and Probabilistic Seismic Microzoning maps for Almaty.These maps align with Eurocode 8 principles,incorporating seismic intensity and engineering parameters like peak ground acceleration(PGA).The new procedure,applied in national projects,has resulted in GSZ maps for the country,seismic microzoning maps for Almaty,and detailed seismic zoning maps for East Kazakhstan.These maps,part of a regulatory document,guide earthquake-resistant design and construction.They offer a comprehensive assessment of seismic hazards,integrating traditional Medvedev-Sponheuer-Karnik(MSK-64)intensity scale points with quantitative parameters like peak ground acceleration.This innovative approach promises to advance methods for quantifying seismic hazards in specific regions.
