The skin,being the largest organ of the human body,serves a critical barrier function by preventing the intrusion of harmful external substances and minimizing moisture loss.The epidermis consists of a stratified epit...The skin,being the largest organ of the human body,serves a critical barrier function by preventing the intrusion of harmful external substances and minimizing moisture loss.The epidermis consists of a stratified epithelium of continuously differentiating keratinocytes(KCs),which originate from the basal layer and progressively migrate upwards to form the stratum corneum.展开更多
基金supported by the National Natural Science Foundation of China(No.82173423)National Science Foundation Projects of Guangdong Province,China(No.2024A1515012346)+2 种基金Shenzhen Basic Research Project(Natural Science Foundation)(Guangdong,China)(No.JCYJ20220530141802005,JCYJ20230807115912025)Shenzhen Nanshan District Science and Technology Major Project(Excellent Youth Fund)(Guangdong,China)(No.NSZD2023030)Scientific Research Project of Huazhong University of Science and Technology Union Shenzhen Hospital(Guangdong,China))(No.YN2021001).
文摘The skin,being the largest organ of the human body,serves a critical barrier function by preventing the intrusion of harmful external substances and minimizing moisture loss.The epidermis consists of a stratified epithelium of continuously differentiating keratinocytes(KCs),which originate from the basal layer and progressively migrate upwards to form the stratum corneum.
