摘要
The skin,being the largest organ of the human body,serves a critical barrier function by preventing the intrusion of harmful external substances and minimizing moisture loss.The epidermis consists of a stratified epithelium of continuously differentiating keratinocytes(KCs),which originate from the basal layer and progressively migrate upwards to form the stratum corneum.
基金
supported by the National Natural Science Foundation of China(No.82173423)
National Science Foundation Projects of Guangdong Province,China(No.2024A1515012346)
Shenzhen Basic Research Project(Natural Science Foundation)(Guangdong,China)(No.JCYJ20220530141802005,JCYJ20230807115912025)
Shenzhen Nanshan District Science and Technology Major Project(Excellent Youth Fund)(Guangdong,China)(No.NSZD2023030)
Scientific Research Project of Huazhong University of Science and Technology Union Shenzhen Hospital(Guangdong,China))(No.YN2021001).