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Independent variations in genome-wide expression, alternative splicing, and DNA methylation in brain tissues among castes of the buff-tailed bumblebee, Bombus terrestris 被引量:1
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作者 Dan Zhu Jin Ge +5 位作者 Siyuan Guo Li Hou Rangjun Shi Xian Zhou Xin Nie Xianhui Wang 《Journal of Genetics and Genomics》 SCIE CAS CSCD 2021年第8期681-694,共14页
Caste differentiation in social hymenopterans is an intriguing example of phenotypic plasticity. However, the co-ordination among gene regulatory factors to mediate caste differentiation remains inconclusive. In this ... Caste differentiation in social hymenopterans is an intriguing example of phenotypic plasticity. However, the co-ordination among gene regulatory factors to mediate caste differentiation remains inconclusive. In this study, we determined the role of gene regulation and related epigenetic processes in pre-imaginal caste differentiation in the primitively eusocial bumblebee Bombus terrestris. By combining RNA-Seq data from Illumina and Pac Bio and accurately quantifying methylation at whole-genomic base pair resolution, we found that queens, workers, and drones mainly differentiate in gene expression but not in alternative splicing and DNA methylation. Gynes are the most distinct with the lowest global level of whole-genomic methylation and with the largest number of caste-specific transcripts and alternative splicing events. By contrast, workers exhibit few uniquely expressed or alternatively spliced genes. Moreover, several genes involved in hormone and neurotransmitter metabolism are related to caste differentiation, whereas several neuropeptides are linked with sex differentiation. Despite little genome-wide association among differential gene expression, splicing, and differential DNA methylation, the overlapped gene ontology(GO) terms point to nutrition-related activity. Therefore, variations in gene regulation correlate with the behavioral differences among castes and highlight the specialization of toolkit genes in bumblebee gynes at the beginning of the adult stage. 展开更多
关键词 Social insects Caste determination PacBio EPIGENETICS Methylome RNA-seq WGBS-seq
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A review of electroslag remelting composite technologies
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作者 Yu Wang Yan-chun Lou +5 位作者 Fang Wang Heng Cao Yun-bao Gao Ling Zhao Zhi Han Meng Li 《China Foundry》 2026年第1期1-19,共19页
Electroslag remelting(ESR) is an important metallurgical process for producing high-purity materials with homogeneous compositions and sound microstructures,and its typical products are ingots or simple castings.The c... Electroslag remelting(ESR) is an important metallurgical process for producing high-purity materials with homogeneous compositions and sound microstructures,and its typical products are ingots or simple castings.The core principle involves the resistive melting of a consumable electrode within a slag pool,followed by the refining of molten metal droplets as they traverse the slag,and subsequent sequential solidification in a water-cooled mold.However,conventional ESR processes face limitations in producing large or complex-shaped components,enhancing production efficiency,achieving highly specialized microstructures,and meeting ultra-high purity demands for advanced applications.Advanced composite ESR technologies have been developed to overcome these limitations by innovatively modifying key process aspects.For instance,electrode systems are improved using vibration,rotation,or multiple electrodes.Enhanced mold design and solidification control are achieved through techniques including conductive molds,mold rotation,and ingot withdrawal.Precise control of the process is realized through the use of protective gas,vacuum,or elevated pressure,as well as the application of external fields such as magnetic fields or ultrasonic vibration.This review comprehensively summarizes these advanced techniques,examining their principles and characteristics,and discussing their specific advantages and challenges. 展开更多
关键词 electroslag remelting(ESR) composite electroslag technology near-net shape casting high purity materials process modification external field assisted casting
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Influence of ultrasonic agitation on dispersion of fibers in a shell mold for investment casting
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作者 Zhi-cheng Feng Kai Lü +2 位作者 Yan Lu Wen-bo Jin Lei Che 《China Foundry》 2026年第1期108-116,共9页
To develop a suitable production process for fiber reinforced investment casting shell mold,three methods were studied:the traditional method(M_(1)),the method of adding fiber into silica sol with mechanical stirring ... To develop a suitable production process for fiber reinforced investment casting shell mold,three methods were studied:the traditional method(M_(1)),the method of adding fiber into silica sol with mechanical stirring and ultrasonic agitation(M_(2)),and the method of adding fiber into slurry with mechanical stirring and ultrasonic agitation for durations of 3,15,30,and 45 min(M_(3)).The bending strength,high-temperature self-load deformation,and thermal conductivity of the shell molds were investigated.The results reveal that the enhancement of fiber dispersion through ultrasonic agitation improves the comprehensive performance of the shell molds.The maximum green bending strength of the shell mold by M_(2) reaches 3.29 MPa,which is 29% higher than that of the shell mold prepared by M_(1).Moreover,the high-temperature self-load deformation of the shell mold is reduced from 0.62% to 0.44%.In addition,simultaneous ultrasonic agitation and mechanical stirring effectively shorten the slurry preparation time while maintaining comparable levels of fiber dispersion.With the process M_(3)-45 min,the fillers are uniformly dispersed in the slurry,and the fired bending strength and the high-temperature self-load deformation reach 6.25 MPa and 0.41%,respectively.Therefore,the proposed ultrasonic agitation route is promising for the fabrication of fiber-reinforced shell molds with excellent fibers dispersion. 展开更多
关键词 investment casting steel fibers fiber-reinforced shell ultrasonic agitation thermal conductivity
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CAST工艺处理效率优化技术探讨
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作者 莫汝松 《山东化工》 2026年第2期77-79,83,共4页
周期循环活性污泥性(CAST)工艺基于序排批注性污泥法(SBR)工艺发展演变而来,因其占地面积小,投资成本低,运行控制较灵活,可根据进水水质对曝气时间、进水量进行调整,在污水处理领域得到广泛的应用。然而,与目前更为主流的AAO工艺相比,C... 周期循环活性污泥性(CAST)工艺基于序排批注性污泥法(SBR)工艺发展演变而来,因其占地面积小,投资成本低,运行控制较灵活,可根据进水水质对曝气时间、进水量进行调整,在污水处理领域得到广泛的应用。然而,与目前更为主流的AAO工艺相比,CAST工艺在脱氮除磷效果方面存在不足,难以满足日趋严格的出水排放标准。因此,针对CAST工艺处理效率的优化提升,研究人员开展了持续的试验与实践。本文对基于CAST工艺的优化提升方式如工艺参数优化、设备设施改造、联合其他工艺进行了探讨,以期为后续CAST工艺的应用及优化提供参考。 展开更多
关键词 CAST工艺 污水处理 优化 技术探讨
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Thermal simulation method for researching solidification process of ductile iron pipe based on heat transfer similarity of characteristic unit of ductile iron pipe
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作者 Gan-chao Zhai Gong-ao Zhu +4 位作者 Shao-dong Hu Bin Yang Jie-yu Zhang Xiang-ru Chen Qi-jie Zhai 《China Foundry》 2026年第1期62-72,共11页
Centrifugal casting of ductile iron pipe is a high-temperature,semi-continuous production process.However,conducting laboratory research on the solidification process of centrifugal casting of ductile iron pipe presen... Centrifugal casting of ductile iron pipe is a high-temperature,semi-continuous production process.However,conducting laboratory research on the solidification process of centrifugal casting of ductile iron pipe presents significant challenges.In this study,a novel research method was introduced for investigating the solidification process of ductile iron pipe,namely thermal simulation of ductile iron pipe.Comparative research was conducted on the microstructure and properties of the thermal simulation sample and the ductile iron pipe.The findings indicate that the thermal simulation sample and ductile iron pipe exhibit good heat transfer similarity and microstructure similarity.The difference of cooling rate between thermal simulation sample and ductile pipe is less than 0.24℃·s^(-1),and the difference of microstructure content of free cementite,ferrite,and pearlite is less than 5%.The tensile strength of annealed ductile iron pipe is 466 MPa,with an elongation of 16.1%and a Brinell hardness of 156.5 HBW.In comparison,the tensile strength of annealed thermal simulation sample is 482.0 MPa,with an elongation of 15.5%and a Brinell hardness of 159.0 HBW.These results suggest that the thermal simulation experimental research method is both scientific and feasible,offering an objective,reliable,and cost-effective approach to laboratory research on ductile iron pipe. 展开更多
关键词 ductile iron pipe centrifugal casting thermal simulation MICROSTRUCTURE mechanical property
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Evolution of microstructure and properties of Cu-12Fe alloys prepared by twin-roll strip casting
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作者 Tian-mo Wu Yuan-xiang Zhang +3 位作者 Shuai-jie Guo Nuo-jin Wang Jian Kang Guo Yuan 《China Foundry》 2026年第1期73-82,共10页
The Cu-12Fe alloy has attracted significant attention due to its excellent electrical conductivity and electromagnetic shielding capability,high strength,cost-effectiveness,and recyclability.In the present work,the Cu... The Cu-12Fe alloy has attracted significant attention due to its excellent electrical conductivity and electromagnetic shielding capability,high strength,cost-effectiveness,and recyclability.In the present work,the Cu-12Fe alloy strip with the thickness of 2.4 mm was successfully produced by twin-roll strip casting.The microstructure and properties of the Cu-12Fe alloy were tailored by cold rolling and aging treatment.The tensile strength of the as-cast strip is approximately 328 MPa and its elongation is 25%.The Fe phase randomly dispersed in the matrix,and the average size of Fe-rich phase is 2μm.Besides,enrichment of Fe phase is observed in the central layer of the strip,results in the formation of the“sandwich structure”.Moreover,the as-cast strip of Cu-12Fe was directly cold-rolled from 2.4 to 0.12 mm.The directly cold-rolled sample after aging at 450℃for 16 h(ProcessⅠ)shows excellent electrical conductivity of 69.5%IACS,the tensile strength and elongation are 513 MPa and 3.8%,the saturation magnetic flux density is 20.1 emu·g^(-1),and the coercive force is 25.2 Oe.In ProcessⅡ,the as-cast strip firstly cold-rolled to 1.2 mm,then aged at 500℃for 1.5 h,followed by cold rolling to 0.12 mm,finally aged at 450℃for 16 h.The sample after ProcessⅡshows the electrical conductivity of 66.3%IACS,the tensile strength of 533 MPa,an elongation of 3.5%,saturation magnetic flux density of 21.4 emu·g^(-1),and the coercive force of 22.3 Oe. 展开更多
关键词 Cu-Fe alloy twin-roll strip casting MICROSTRUCTURE mechanical properties thermal aging electrical conductivity
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Characterization of the formation of slag rims of mold powder during hypo-peritectic steel continuous casting based on full-sectional microstructures
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作者 Zhiqiang Peng Zibing Hou +2 位作者 Shuxian Xu Ping Tang Guanghua Wen 《International Journal of Minerals,Metallurgy and Materials》 2026年第2期567-578,共12页
A full-sectional microstructure characterization method was developed to investigate the formation of coarse slag rims during the continuous casting of hypo-peritectic steel.The cross-sectional microstructural analysi... A full-sectional microstructure characterization method was developed to investigate the formation of coarse slag rims during the continuous casting of hypo-peritectic steel.The cross-sectional microstructural analysis of typical slag rims for two highly crystalline powders revealed that their formation was primarily driven by the solidification of the liquid slag.Distinct differences were observed in the microstructures of slag rims from the two powders.Powder A(characterized by a higher breaking temperature and viscosity)displayed alternating lamellar microstructures of coarse and fine phases,with the coarse phases composed of akermanite-gehlenite transition phases.In contrast,powder B(with a lower breaking temperature and viscosity)predominantly comprised regular akermanite-gehlenite crystals interspersed with a certain amount of glassy phases.Numerical simulations of a three-phase fluid flow coupled with heat transfer indicate that slag rim formation correlates with mold oscillation.Solidification of the liquid slag at the slag rim front predominantly occurs during the negative stroke of the mold oscillation.The average heating rate during the ascending stage of the mold reaches approximately 100 K·s^(−1),whereas the average cooling rate during the descending stage attains 400 K·s^(−1).This temperature variation leads to the formation of lamellar microstructures,whereas the ascending stage promotes the formation of coarse structures and thicker slag rims.Based on the powder properties,two distinct formation pathways exist for highly crystalline mold powders.For the powders with a higher breaking temperature,higher viscosity,and narrower solidification range(powder A),coarse microstructures and thicker slag rims were preferentially formed.For powders with lower breaking temperature and viscosity and wider solidification ranges(powder B),the liquid slag resisted rapid solidification,and the extended mushy zone allowed the partial liquid slag to persist at the slag rim front,promoting the formation of a thin slag rim.This study enhances the understanding of slag rim formation in highly crystalline mold powders and provides critical insights into the control of longitudinal surface cracks in hypo-peritectic steel. 展开更多
关键词 hypo-peritectic steel longitudinal surface crack continuous casting slag rim full-sectional microstructures mold powder
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Tissue engineering tubular scaffold fabrication for esophageal regeneration
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作者 Xingyu Zhou Xianglin Zhang Bin Wu 《Bio-Design and Manufacturing》 2026年第1期100-121,I0018,共23页
The esophagus is a tubular organ essential for maintaining normal eating function in humans.However,the replacement of the esophagus remains challenging in clinical settings.Although tissue engineering scaffolds are a... The esophagus is a tubular organ essential for maintaining normal eating function in humans.However,the replacement of the esophagus remains challenging in clinical settings.Although tissue engineering scaffolds are a promising alternative solution,their fabrication is difficult due to the complex structure and function of the esophagus.This review describes the existing fabrication methods for esophageal tubular scaffolds,including decellularization,casting,electrospinning,three dimensional(3 D)bioprinting,and pin-frogging.Also discussed are the stimulation cues of the fabricated esophageal tubular scaffold that induce esophageal muscle and epithelial cells.Finally,this review emphasizes three important concerns for esophageal tubular scaffolds:leakage and porosity,elasticity and proliferation of smooth muscle cells,and biocompatibility and structural fidelity of biomaterials. 展开更多
关键词 Esophageal tissue engineering DECELLULARIZATION CASTING ELECTROSPINNING Three-dimensional(3D)bioprinting
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Heat-resistant Microporous Star-shaped Casting Polyurethane for Airless Electric Bicycle Tires
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作者 Chao-Yang Yuan Lei Shi +6 位作者 Shang-Chao Ji Hai-Long Chen Xiao Tong Zi-Ying Hao Xiao-Da Pan Xian-Ze Yin Long Zheng 《Chinese Journal of Polymer Science》 2026年第2期474-484,I0014,共12页
Airless tires are essential for enhancing the safety,reliability,and convenience of maintenance of electric bicycles.Polyurethane(PU)is considered a promising candidate for such applications owing to its versatile pro... Airless tires are essential for enhancing the safety,reliability,and convenience of maintenance of electric bicycles.Polyurethane(PU)is considered a promising candidate for such applications owing to its versatile properties.However,their use is limited by insufficient heat resistance and excessive dynamic heat generation under cyclic loading.In this study,star-shaped trifunctional polypropylene glycerol(PPG3)was incorporated into conventional poly(tetramethylene glycol)(PTMG)and 4,4'-methylenediphenyl diisocyanate(MDI)-based systems to construct microporous star-shaped casting polyurethanes(SCPU),with water serving as a green foaming agent.Unlike conventional small-molecule trifunctional crosslinkers that create junctions within hard segment domains,PPG3 introduces long flexible arms between the hard segments,anchoring the crosslinking points at its molecular core.The large steric hindrance of PPG3 effectively suppresses soft segment crystallization and lowers the degree of microphase separation,whereas the crosslinked network restricts chain mobility,thereby reducing dynamic heat generation.These structural features also enhance the heat resistance,yielding a softening temperature of 183℃,which is 30.9%higher than that of polyurethane without PPG3.When applied to airless tires by casting SCPU into rubber treads,the fabricated hybrid airless tires achieved a rolling distance of over 3000 km under a load of 65 kg at 25km/h without structural failure,satisfying practical performance requirements.This strategy offers a simple,solvent-free,and environmentally friendly process,underscoring the potential of SCPU for scalable production of high-performance airless tires. 展开更多
关键词 Microporous star-shaped casting polyurethane Microphase separation Heat resistance Airless tire
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BearFusionNet:A Multi-Stream Attention-Based Deep Learning Framework with Explainable AI for Accurate Detection of Bearing Casting Defects
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作者 Md.Ehsanul Haque Md.Nurul Absur +3 位作者 Fahmid Al Farid Md Kamrul Siam Jia Uddin Hezerul Abdul Karim 《Computers, Materials & Continua》 2026年第3期845-871,共27页
Manual inspection of onba earing casting defects is not realistic and unreliable,particularly in the case of some micro-level anomalies which lead to major defects on a large scale.To address these challenges,we propo... Manual inspection of onba earing casting defects is not realistic and unreliable,particularly in the case of some micro-level anomalies which lead to major defects on a large scale.To address these challenges,we propose BearFusionNet,an attention-based deep learning architecture with multi-stream,which merges both DenseNet201 and MobileNetV2 for feature extraction with a classification head inspired by VGG19.This hybrid design,figuratively beaming from one layer to another,extracts the enormity of representations on different scales,backed by a prepreprocessing pipeline that brings defect saliency to the fore through contrast adjustment,denoising,and edge detection.The use of multi-head self-attention enhances feature fusion,enabling the model to capture both large and small spatial features.BearFusionNet achieves an accuracy of 99.66%and Cohen’s kappa score of 0.9929 in Kaggle’s Real-life Industrial Casting Defects dataset.Both McNemar’s and Wilcoxon signed-rank statistical tests,as well as fivefold cross-validation,are employed to assess the robustness of our proposed model.To interpret the model,we adopt Grad-Cam visualizations,which are the state of the art standard.Furthermore,we deploy BearFusionNet as a webbased system for near real-time inference(5-6 s per prediction),which enables the quickest yet accurate detection with visual explanations.Overall,BearFusionNet is an interpretable,accurate,and deployable solution that can automatically detect casting defects,leading to significant advances in the innovative industrial environment. 展开更多
关键词 Bearing casting defects defects classification fault detection quality inspection of bearing Industry 4.0
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Controlling externally solidified crystals and porosity for enhancing mechanical properties of a die-casting aluminum-silicon alloy
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作者 Yi-hui Zhang Xiang-yi Jiao +6 位作者 Peng-yue Wang Yi-xian Liu Jin-rui Wang Wen-ning Liu Li-jun Shi Cheng-gang Wang Shou-mei Xiong 《China Foundry》 2026年第1期94-100,共7页
The effects of the high pressure die casting(HPDC)processes on porosity,microstructure,and mechanical properties of heat-treatment-free aluminum silicon(Al-Si)alloys have long been a focal point in automotive die-cast... The effects of the high pressure die casting(HPDC)processes on porosity,microstructure,and mechanical properties of heat-treatment-free aluminum silicon(Al-Si)alloys have long been a focal point in automotive die-casting research.In this work,the combined effect of shot sleeve materials and slow shot speeds on porosity,microstructure and mechanical properties of a newly designed HPDC Al-Si alloy was investigated.Results show that employing a ceramic shot sleeve or increasing the slow shot speed significantly reduces both the average size and area fraction of externally solidified crystals(ESCs),as well as the average pore size and volume fraction.When the slow shot speed is increased from 0.05 m·s^(-1)to 0.1 m·s^(-1),the pore volume fraction decreases by 10.2%in steel-shot-sleeve samples,compared to a substantial 67.1%reduction in ceramic-shot-sleeve samples.At a slow shot speed of 0.1 m·s^(-1),castings produced with a ceramic shot sleeve exhibit superior mechanical properties:8.3%higher yield strength,17.4%greater tensile strength,and an 81.4%improvement in elongation,relative to those from a steel shot sleeve.These findings provide valuable insights for minimizing porosity and coarse ESCs in die castings,offering promising potential for broader industrial applications. 展开更多
关键词 high pressure die casting aluminum-silicon alloy externally solidified crystals POROSITY shot sleeve
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Automatic gating and riser system design and defect control for K4169 superalloy guide blade casting based on parametric 3D modeling-simulation integrated system
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作者 Le-chuan Li Ya-jun Yin +4 位作者 Bing-zheng Fan Guo-yan Shui Xiao-yuan Ji Jian-xin Zhou Lei Jin 《China Foundry》 2026年第1期20-30,共11页
Automation and intelligence have become the primary trends in the design of investment casting processes.However,the design of gating and riser systems still lacks precise quantitative evaluation criteria.Numerical si... Automation and intelligence have become the primary trends in the design of investment casting processes.However,the design of gating and riser systems still lacks precise quantitative evaluation criteria.Numerical simulation plays a significant role in quantitatively evaluating current processes and making targeted improvements,but its limitations lie in the inability to dynamically reflect the formation outcomes of castings under varying process conditions,making real-time adjustments to gating and riser designs challenging.In this study,an automated design model for gating and riser systems based on integrated parametric 3D modeling-simulation framework is proposed,which enhances the flexibility and usability of evaluating the casting process by simulation.Firstly,geometric feature extraction technology is employed to obtain the geometric information of the target casting.Based on this information,an automated design framework for gating and riser systems is established,incorporating multiple structural parameters for real-time process control.Subsequently,the simulation results for various structural parameters are analyzed,and the influence of these parameters on casting formation is thoroughly investigated.Finally,the optimal design scheme is generated and validated through experimental verification.Simulation analysis and experimental results show that using a larger gate neck(24 mm in side length) and external risers promotes a more uniform temperature distribution and a more stable flow state,effectively eliminating shrinkage cavities and enhancing process yield by 15%. 展开更多
关键词 numerical simulation automatic design investment casting parametric 3D modeling gating and riser system
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Influence of mold wall thickness on morphologies of defect band in high-pressure die casting technology
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作者 Zhen-yu Sun Wen-bo Yu +4 位作者 Jun-jie Li Wei-chen Zheng Guang-rui Wang Jian-ru Fang Shou-mei Xiong 《China Foundry》 2026年第1期31-36,共6页
In order to investigate the effect of die wall thickness on morphologies of defect band,a stepped mold with a wall thickness of 5 mm,4 mm,3 mm,2 mm,and 1 mm was designed to carry out high pressure die casting experime... In order to investigate the effect of die wall thickness on morphologies of defect band,a stepped mold with a wall thickness of 5 mm,4 mm,3 mm,2 mm,and 1 mm was designed to carry out high pressure die casting experiments with AlSi10 MgMn alloy.For castings with wall thickness of 2-4 mm,the ratio of the mean defect band width(w)and mean grain size(d)in the defect band(w/d)ranges 7-18,while it increases to 24.47 for the 5 mm-thick casting.This difference is related with the filling speed and the distribution of externally solidified crystals(ESCs).The mold flow analysis indicates that the filling speed decreases from 25.41 m·s^(-1)to 11.07 m·s^(-1)when wall thickness increases from 2 mm to 5 mm.Due to the decreasing filling speed along the wall thickness,ESCs gradually diffuse from the center to the defect band,which keep the shear strength in the defect band at a high-level during filling.Meanwhile,the shear strength generated during the filling also decreases as the shear rate drops.Finally,the defect bands in the 5 mm-thick region become widen and indistinct,and the porosity is as high as 5.25%. 展开更多
关键词 AlSi10MgMn high pressure die casting defect band mold flow analysis externally solidified crystals
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可控飞行撞地事故系统性分析及韧性演化模型研究
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作者 刘俊杰 毛馨 张爱华 《综合运输》 2026年第2期101-107,124,共8页
为揭示飞行场景中航空运输系统应对突发扰动的机制,基于安全韧性与耗散结构理论对航空安全网(ASN)中165起事故进行系统性分析。运用CAST方法提取事故中涉及的扰动因素及韧性能力失效因素,构建韧性演化熵数学模型,并利用系统动力学仿真... 为揭示飞行场景中航空运输系统应对突发扰动的机制,基于安全韧性与耗散结构理论对航空安全网(ASN)中165起事故进行系统性分析。运用CAST方法提取事故中涉及的扰动因素及韧性能力失效因素,构建韧性演化熵数学模型,并利用系统动力学仿真软件进行动态演化模拟及可视化展示。结果表明:突发扰动因素产生的正熵与机组响应、处置能力等产生的负熵之间的动态平衡关系,能够反映实际飞行中可控飞行撞地事件的不同应对情景,以“熵”的形式揭示了不同后果程度事故的致因机制。研究结果可为系统性事故分析及多重扰动耦合作用下航空运输系统安全韧性研究提供新的思路。 展开更多
关键词 航空安全 安全韧性 可控飞行撞地(CFIT) 系统理论因果分析(CAST) 耗散结构 系统动力学仿真
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牛至精油对芦花鸡肉质相关基因表达的影响 被引量:2
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作者 吴涛 江小帆 +5 位作者 杨发荣 魏玉明 陈国顺 蔡原 焦婷 赵生国 《家畜生态学报》 北大核心 2025年第5期21-27,共7页
试验旨在探究饲粮中添加不同水平牛至精油对芦花鸡肉品质及肉质相关基因表达的影响。选取49日龄健康芦花鸡120只体重(1478.75±85.81)g,随机分为4组,每组3个重复,每个重复10只鸡,各组饲粮分别添加0(Q8组)、50(QO50组)、100(QO100组)... 试验旨在探究饲粮中添加不同水平牛至精油对芦花鸡肉品质及肉质相关基因表达的影响。选取49日龄健康芦花鸡120只体重(1478.75±85.81)g,随机分为4组,每组3个重复,每个重复10只鸡,各组饲粮分别添加0(Q8组)、50(QO50组)、100(QO100组)和150 mg/kg(QO150组)的牛至精油,试验期75 d(预试期3 d,正试期72 d)。饲喂结束后屠宰并测定肉品质及肉质相关基因的表达量。结果表明:1)与Q8组相比,藜麦饲粮中添加牛至精油对芦花鸡胸肌LRP1基因有一定影响,显著提高QO100组LRP1基因mRNA表达量(P<0.05)。2)与Q8组相比,藜麦饲粮中添加牛至精油显著降低了QO50组腿肌组织中CAPN1基因mRNA表达量(P<0.05)。3)胸肌组织中,LRP1基因的表达水平与失水率、滴水损失、剪切力呈显著正相关(P<0.05);CAST基因的表达水平与滴水损失、剪切力呈显著正相关(P<0.05);CAPN1基因的表达水平与剪切力呈显著负相关(P<0.05)。4)腿肌组织中,LRP1基因表达水平与剪切力呈显著正相关(P<0.05);CAST基因的表达水平与失水率和滴水损失呈显著正相关(P<0.05);CAPN1基因的表达水平与滴水损失呈极显著负相关(P<0.01),与剪切力呈显著负相关(P<0.05)。由此可见,饲粮中添加牛至精油对肌肉组织中LRP1基因、CAPN1基因的表达量有一定影响,且LRP1、CAST、CAPN1基因与嫩度相关肉品质指标存在显著相关性。 展开更多
关键词 肉质相关基因 CAST基因 CAPN1基因 LRP1基因 关联性分析
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猪CAST基因多态性与肉质性状的关联分析
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作者 张镯 杨又兵 周臣 《中国畜牧杂志》 北大核心 2025年第5期122-126,共5页
钙蛋白酶抑制蛋白(Calpastatin,CAST)基因参与肌肉生长过程中蛋白质的代谢更新,从而影响肌肉的嫩度。本研究以138头大白×梅山猪F2代和81头大白×梅山猪F1代猪为试验材料,研究CAST基因的遗传效应。结果表明,CAST基因片段在猪群... 钙蛋白酶抑制蛋白(Calpastatin,CAST)基因参与肌肉生长过程中蛋白质的代谢更新,从而影响肌肉的嫩度。本研究以138头大白×梅山猪F2代和81头大白×梅山猪F1代猪为试验材料,研究CAST基因的遗传效应。结果表明,CAST基因片段在猪群中存在3个Msp I和4个Hinf I酶切位点,其中各有1个Msp I和Hinf I酶切多态性位点。大白×梅山F2代群体中,CAST基因Msp I位点多态性与眼肌宽度显著相关,CASTCD比CASTCC基因型个体宽8.60%(P<0.05);与眼肌面积极显著相关,CASTCD比CASTCC基因型个体大9.40%(P<0.01)。CAST基因Hinf I位点多态性与眼肌宽度、眼肌面积与股二头肌pH显著相关。CASTEF基因型个体的眼肌宽度比CASTEE高8.17%(P<0.05);CASTEF基因型个体的眼肌面积比CASTEE高9.40%(P<0.01)。CAST基因Msp I、Hinf I位点多态性均与肌内脂肪含量显著相关,CAST基因Msp I、Hinf I位点杂合子个体比纯合子高13.01%(P<0.05),与肌内水分极显著相关(P<0.01)。在大白×梅山猪F1代群体中,CAST基因Msp I位点与眼肌pH显著相关。本研究为进一步分析猪胴体发育及肉质改良提供了基础。 展开更多
关键词 CAST基因 PCR-RFLP 多态性
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Numerical simulation of the deformation risk in thin slab continuous casting process with liquid core reduction 被引量:2
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作者 Zhida Zhang Jize Chen +3 位作者 Cheng Ji Yutang Ma Miaoyong Zhu Wenxue Wang 《International Journal of Minerals,Metallurgy and Materials》 2025年第5期1114-1127,共14页
The application of liquid core reduction(LCR)technology in thin slab continuous casting can refine the internal microstruc-tures of slabs and improve their production efficiency.To avoid crack risks caused by large de... The application of liquid core reduction(LCR)technology in thin slab continuous casting can refine the internal microstruc-tures of slabs and improve their production efficiency.To avoid crack risks caused by large deformation during the LCR process and to minimize the thickness of the slab in bending segments,the maximum theoretical reduction amount and the corresponding reduction scheme for the LCR process must be determined.With SPA-H weathering steel as a specific research steel grade,the distributions of tem-perature and deformation fields of a slab with the LCR process were analyzed using a three-dimensional thermal-mechanical finite ele-ment model.High-temperature tensile tests were designed to determine the critical strain of corner crack propagation and intermediate crack initiation with various strain rates and temperatures,and a prediction model of the critical strain for two typical cracks,combining the effects of strain rate and temperature,was proposed by incorporating the Zener-Hollomon parameter.The crack risks with different LCR schemes were calculated using the crack risk prediction model,and the maximum theoretical reduction amount for the SPA-H slab with a transverse section of 145 mm×1600 mm was 41.8 mm,with corresponding reduction amounts for Segment 0 to Segment 4 of 15.8,7.3,6.5,6.4,and 5.8 mm,respectively. 展开更多
关键词 thin slab continuous casting liquid core reduction three-dimensional thermal-mechanical critical strain crack risk maxim-um theoretical reduction amount
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A review of the progress and challenges of counter-gravity casting 被引量:1
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作者 Dafan Du Jiatuo An +1 位作者 Anping Dong Baode Sun 《Journal of Materials Science & Technology》 2025年第13期1-26,共26页
Counter-gravity casting(CGC)is a widely adopted material processing technique in metals due to its notable benefits,including enhanced filling behavior,reduced defect occurrence,and elevated mechani-cal properties.It ... Counter-gravity casting(CGC)is a widely adopted material processing technique in metals due to its notable benefits,including enhanced filling behavior,reduced defect occurrence,and elevated mechani-cal properties.It plays a pivotal role in fabricating intricate,high-quality components.After its inception in the early 1900s,various CGC processes have emerged,such as low-pressure,counter-pressure,vac-uum suction,and adjusted pressure casting,which are explored in this discourse with an eye toward further advancements.Despite CGC’s superiority over traditional gravity casting and other manufacturing methodologies,specific issues and constraints persist within CGC.This paper endeavors to provide a com-prehensive overview of the historical progression of CGC,its recent developments,and the associated re-search aspects,encompassing topics like filling processes,solidification,microstructural transformations,and the resultant mechanical properties of the fabricated products.Additionally,this paper offers insights into the future challenges and opportunities of CGC. 展开更多
关键词 CGC(counter-gravity casting) SOLIDIFICATION FILLING Pressure CASTING
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Buoyancy characteristic analysis and optimization of precast concrete slab track during casting process of self-compacting concrete 被引量:1
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作者 Pengsong Wang Tao Xin +2 位作者 Peng Chen Sen Wang Di Cheng 《Railway Sciences》 2025年第2期159-173,共15页
Purpose–The precast concrete slab track(PST)has advantages of fewer maintenance frequencies,better smooth rides and structural stability,which has been widely applied in urban rail transit.Precise positioning of prec... Purpose–The precast concrete slab track(PST)has advantages of fewer maintenance frequencies,better smooth rides and structural stability,which has been widely applied in urban rail transit.Precise positioning of precast concrete slab(PCS)is vital for keeping the initial track regularity.However,the cast-in-place process of the self-compacting concrete(SCC)filling layer generally causes a large deformation of PCS due to the water-hammer effect of flowing SCC,even cracking of PCS.Currently,the buoyancy characteristic and influencing factors of PCS during the SCC casting process have not been thoroughly studied in urban rail transit.Design/methodology/approach–In this work,a Computational Fluid Dynamics(CFD)model is established to calculate the buoyancy of PCS caused by the flowing SCC.The main influencing factors,including the inlet speed and flowability of SCC,have been analyzed and discussed.A new structural optimization scheme has been proposed for PST to reduce the buoyancy caused by the flowing SCC.Findings–The simulation and field test results showed that the buoyancy and deformation of PCS decreased obviously after adopting the new scheme.Originality/value–The findings of this study can provide guidance for the control of the deformation of PCS during the SCC construction process. 展开更多
关键词 Casting process Buoyancy characteristics Precast concrete slab track SIMULATION Field test OPTIMIZATION
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Influence of surface layer slurry temperature on surface cracks and holes of ZTC4 titanium alloy by investment casting 被引量:1
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作者 Wei-dong Li Xu-na Shi 《China Foundry》 2025年第1期90-98,共9页
In this work,the influences of surface layer slurry at different temperatures(10℃,14℃,18℃,22℃)on wax patterns deformation,shrinkage,slurry coating characteristics,and the surface quality of the casting were invest... In this work,the influences of surface layer slurry at different temperatures(10℃,14℃,18℃,22℃)on wax patterns deformation,shrinkage,slurry coating characteristics,and the surface quality of the casting were investigated by using a single factor variable method.The surface morphologies of the shell molds produced by different temperatures of the surface(first)layer slurries were observed via electron microscopy.Furthermore,the microscopic composition of these shell molds was obtained by EDS,and the osmotic effect of the slurry on the wax patterns at different temperatures was also assessed by the PZ-200 Contact Angle detector.The forming reasons for the surface cracks and holes of thick and large ZTC4 titanium alloy by investment casting were analyzed.The experimental results show that the surface of the shell molds prepared by the surface layer slurry with a low temperature exhibits noticeable damage,which is mainly due to the poor coating performance and the serious expansion and contraction of wax pattern at low temperatures.The second layer shell material(SiO_(2),Al_(2)O_(3))immerses into the crack area of the surface layer,contacts and reacts with the molten titanium to form surface cracks and holes in the castings.With the increase of the temperature of surface layer slurry,the damage to the shell surface tends to weaken,and the composition of the shell molds'surface becomes more uniform with less impurities.The results show that the surface layer slurry at 22℃is evenly coated on the surface of the wax patterns with appropriate thickness,and there is no surface shell mold rupture caused by sliding slurry after sand leaching.The surface layer slurry temperature is consistent with the wax pattern temperature and the workshop temperature,so there is no damage of the surface layer shell caused by expansion and contraction.Therefore,the shell mold prepared by the surface layer slurry at this temperature has good integrity,isolating the contact between the low inert shell material and the titanium liquid effectively,and the ZTC4 titanium alloy cylinder casting prepared by this shell mold is smooth,without cracks and holes. 展开更多
关键词 titanium alloy surface layer slurry surface cracks surface holes investment casting
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