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Independent variations in genome-wide expression, alternative splicing, and DNA methylation in brain tissues among castes of the buff-tailed bumblebee, Bombus terrestris 被引量:1
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作者 Dan Zhu Jin Ge +5 位作者 Siyuan Guo Li Hou Rangjun Shi Xian Zhou Xin Nie Xianhui Wang 《Journal of Genetics and Genomics》 SCIE CAS CSCD 2021年第8期681-694,共14页
Caste differentiation in social hymenopterans is an intriguing example of phenotypic plasticity. However, the co-ordination among gene regulatory factors to mediate caste differentiation remains inconclusive. In this ... Caste differentiation in social hymenopterans is an intriguing example of phenotypic plasticity. However, the co-ordination among gene regulatory factors to mediate caste differentiation remains inconclusive. In this study, we determined the role of gene regulation and related epigenetic processes in pre-imaginal caste differentiation in the primitively eusocial bumblebee Bombus terrestris. By combining RNA-Seq data from Illumina and Pac Bio and accurately quantifying methylation at whole-genomic base pair resolution, we found that queens, workers, and drones mainly differentiate in gene expression but not in alternative splicing and DNA methylation. Gynes are the most distinct with the lowest global level of whole-genomic methylation and with the largest number of caste-specific transcripts and alternative splicing events. By contrast, workers exhibit few uniquely expressed or alternatively spliced genes. Moreover, several genes involved in hormone and neurotransmitter metabolism are related to caste differentiation, whereas several neuropeptides are linked with sex differentiation. Despite little genome-wide association among differential gene expression, splicing, and differential DNA methylation, the overlapped gene ontology(GO) terms point to nutrition-related activity. Therefore, variations in gene regulation correlate with the behavioral differences among castes and highlight the specialization of toolkit genes in bumblebee gynes at the beginning of the adult stage. 展开更多
关键词 Social insects Caste determination PacBio EPIGENETICS Methylome RNA-seq WGBS-seq
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牛至精油对芦花鸡肉质相关基因表达的影响
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作者 吴涛 江小帆 +5 位作者 杨发荣 魏玉明 陈国顺 蔡原 焦婷 赵生国 《家畜生态学报》 北大核心 2025年第5期21-27,共7页
试验旨在探究饲粮中添加不同水平牛至精油对芦花鸡肉品质及肉质相关基因表达的影响。选取49日龄健康芦花鸡120只体重(1478.75±85.81)g,随机分为4组,每组3个重复,每个重复10只鸡,各组饲粮分别添加0(Q8组)、50(QO50组)、100(QO100组)... 试验旨在探究饲粮中添加不同水平牛至精油对芦花鸡肉品质及肉质相关基因表达的影响。选取49日龄健康芦花鸡120只体重(1478.75±85.81)g,随机分为4组,每组3个重复,每个重复10只鸡,各组饲粮分别添加0(Q8组)、50(QO50组)、100(QO100组)和150 mg/kg(QO150组)的牛至精油,试验期75 d(预试期3 d,正试期72 d)。饲喂结束后屠宰并测定肉品质及肉质相关基因的表达量。结果表明:1)与Q8组相比,藜麦饲粮中添加牛至精油对芦花鸡胸肌LRP1基因有一定影响,显著提高QO100组LRP1基因mRNA表达量(P<0.05)。2)与Q8组相比,藜麦饲粮中添加牛至精油显著降低了QO50组腿肌组织中CAPN1基因mRNA表达量(P<0.05)。3)胸肌组织中,LRP1基因的表达水平与失水率、滴水损失、剪切力呈显著正相关(P<0.05);CAST基因的表达水平与滴水损失、剪切力呈显著正相关(P<0.05);CAPN1基因的表达水平与剪切力呈显著负相关(P<0.05)。4)腿肌组织中,LRP1基因表达水平与剪切力呈显著正相关(P<0.05);CAST基因的表达水平与失水率和滴水损失呈显著正相关(P<0.05);CAPN1基因的表达水平与滴水损失呈极显著负相关(P<0.01),与剪切力呈显著负相关(P<0.05)。由此可见,饲粮中添加牛至精油对肌肉组织中LRP1基因、CAPN1基因的表达量有一定影响,且LRP1、CAST、CAPN1基因与嫩度相关肉品质指标存在显著相关性。 展开更多
关键词 肉质相关基因 CAST基因 CAPN1基因 LRP1基因 关联性分析
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猪CAST基因多态性与肉质性状的关联分析
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作者 张镯 杨又兵 周臣 《中国畜牧杂志》 北大核心 2025年第5期122-126,共5页
钙蛋白酶抑制蛋白(Calpastatin,CAST)基因参与肌肉生长过程中蛋白质的代谢更新,从而影响肌肉的嫩度。本研究以138头大白×梅山猪F2代和81头大白×梅山猪F1代猪为试验材料,研究CAST基因的遗传效应。结果表明,CAST基因片段在猪群... 钙蛋白酶抑制蛋白(Calpastatin,CAST)基因参与肌肉生长过程中蛋白质的代谢更新,从而影响肌肉的嫩度。本研究以138头大白×梅山猪F2代和81头大白×梅山猪F1代猪为试验材料,研究CAST基因的遗传效应。结果表明,CAST基因片段在猪群中存在3个Msp I和4个Hinf I酶切位点,其中各有1个Msp I和Hinf I酶切多态性位点。大白×梅山F2代群体中,CAST基因Msp I位点多态性与眼肌宽度显著相关,CASTCD比CASTCC基因型个体宽8.60%(P<0.05);与眼肌面积极显著相关,CASTCD比CASTCC基因型个体大9.40%(P<0.01)。CAST基因Hinf I位点多态性与眼肌宽度、眼肌面积与股二头肌pH显著相关。CASTEF基因型个体的眼肌宽度比CASTEE高8.17%(P<0.05);CASTEF基因型个体的眼肌面积比CASTEE高9.40%(P<0.01)。CAST基因Msp I、Hinf I位点多态性均与肌内脂肪含量显著相关,CAST基因Msp I、Hinf I位点杂合子个体比纯合子高13.01%(P<0.05),与肌内水分极显著相关(P<0.01)。在大白×梅山猪F1代群体中,CAST基因Msp I位点与眼肌pH显著相关。本研究为进一步分析猪胴体发育及肉质改良提供了基础。 展开更多
关键词 CAST基因 PCR-RFLP 多态性
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Buoyancy characteristic analysis and optimization of precast concrete slab track during casting process of self-compacting concrete 被引量:1
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作者 Pengsong Wang Tao Xin +2 位作者 Peng Chen Sen Wang Di Cheng 《Railway Sciences》 2025年第2期159-173,共15页
Purpose–The precast concrete slab track(PST)has advantages of fewer maintenance frequencies,better smooth rides and structural stability,which has been widely applied in urban rail transit.Precise positioning of prec... Purpose–The precast concrete slab track(PST)has advantages of fewer maintenance frequencies,better smooth rides and structural stability,which has been widely applied in urban rail transit.Precise positioning of precast concrete slab(PCS)is vital for keeping the initial track regularity.However,the cast-in-place process of the self-compacting concrete(SCC)filling layer generally causes a large deformation of PCS due to the water-hammer effect of flowing SCC,even cracking of PCS.Currently,the buoyancy characteristic and influencing factors of PCS during the SCC casting process have not been thoroughly studied in urban rail transit.Design/methodology/approach–In this work,a Computational Fluid Dynamics(CFD)model is established to calculate the buoyancy of PCS caused by the flowing SCC.The main influencing factors,including the inlet speed and flowability of SCC,have been analyzed and discussed.A new structural optimization scheme has been proposed for PST to reduce the buoyancy caused by the flowing SCC.Findings–The simulation and field test results showed that the buoyancy and deformation of PCS decreased obviously after adopting the new scheme.Originality/value–The findings of this study can provide guidance for the control of the deformation of PCS during the SCC construction process. 展开更多
关键词 Casting process Buoyancy characteristics Precast concrete slab track SIMULATION Field test OPTIMIZATION
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Influence of surface layer slurry temperature on surface cracks and holes of ZTC4 titanium alloy by investment casting 被引量:1
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作者 Wei-dong Li Xu-na Shi 《China Foundry》 2025年第1期90-98,共9页
In this work,the influences of surface layer slurry at different temperatures(10℃,14℃,18℃,22℃)on wax patterns deformation,shrinkage,slurry coating characteristics,and the surface quality of the casting were invest... In this work,the influences of surface layer slurry at different temperatures(10℃,14℃,18℃,22℃)on wax patterns deformation,shrinkage,slurry coating characteristics,and the surface quality of the casting were investigated by using a single factor variable method.The surface morphologies of the shell molds produced by different temperatures of the surface(first)layer slurries were observed via electron microscopy.Furthermore,the microscopic composition of these shell molds was obtained by EDS,and the osmotic effect of the slurry on the wax patterns at different temperatures was also assessed by the PZ-200 Contact Angle detector.The forming reasons for the surface cracks and holes of thick and large ZTC4 titanium alloy by investment casting were analyzed.The experimental results show that the surface of the shell molds prepared by the surface layer slurry with a low temperature exhibits noticeable damage,which is mainly due to the poor coating performance and the serious expansion and contraction of wax pattern at low temperatures.The second layer shell material(SiO_(2),Al_(2)O_(3))immerses into the crack area of the surface layer,contacts and reacts with the molten titanium to form surface cracks and holes in the castings.With the increase of the temperature of surface layer slurry,the damage to the shell surface tends to weaken,and the composition of the shell molds'surface becomes more uniform with less impurities.The results show that the surface layer slurry at 22℃is evenly coated on the surface of the wax patterns with appropriate thickness,and there is no surface shell mold rupture caused by sliding slurry after sand leaching.The surface layer slurry temperature is consistent with the wax pattern temperature and the workshop temperature,so there is no damage of the surface layer shell caused by expansion and contraction.Therefore,the shell mold prepared by the surface layer slurry at this temperature has good integrity,isolating the contact between the low inert shell material and the titanium liquid effectively,and the ZTC4 titanium alloy cylinder casting prepared by this shell mold is smooth,without cracks and holes. 展开更多
关键词 titanium alloy surface layer slurry surface cracks surface holes investment casting
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Numerical simulation of the deformation risk in thin slab continuous casting process with liquid core reduction 被引量:1
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作者 Zhida Zhang Jize Chen +3 位作者 Cheng Ji Yutang Ma Miaoyong Zhu Wenxue Wang 《International Journal of Minerals,Metallurgy and Materials》 2025年第5期1114-1127,共14页
The application of liquid core reduction(LCR)technology in thin slab continuous casting can refine the internal microstruc-tures of slabs and improve their production efficiency.To avoid crack risks caused by large de... The application of liquid core reduction(LCR)technology in thin slab continuous casting can refine the internal microstruc-tures of slabs and improve their production efficiency.To avoid crack risks caused by large deformation during the LCR process and to minimize the thickness of the slab in bending segments,the maximum theoretical reduction amount and the corresponding reduction scheme for the LCR process must be determined.With SPA-H weathering steel as a specific research steel grade,the distributions of tem-perature and deformation fields of a slab with the LCR process were analyzed using a three-dimensional thermal-mechanical finite ele-ment model.High-temperature tensile tests were designed to determine the critical strain of corner crack propagation and intermediate crack initiation with various strain rates and temperatures,and a prediction model of the critical strain for two typical cracks,combining the effects of strain rate and temperature,was proposed by incorporating the Zener-Hollomon parameter.The crack risks with different LCR schemes were calculated using the crack risk prediction model,and the maximum theoretical reduction amount for the SPA-H slab with a transverse section of 145 mm×1600 mm was 41.8 mm,with corresponding reduction amounts for Segment 0 to Segment 4 of 15.8,7.3,6.5,6.4,and 5.8 mm,respectively. 展开更多
关键词 thin slab continuous casting liquid core reduction three-dimensional thermal-mechanical critical strain crack risk maxim-um theoretical reduction amount
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Influence of Casting Defects on Weldability of a Nickel-Based Superalloy
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作者 Chu Qingquan Hou Xingyu +4 位作者 Cheng Yin Qin Jian Wang Shiyang Sun Yuan Sun Xiaofeng 《稀有金属材料与工程》 北大核心 2025年第8期1917-1925,共9页
The impact of casting defects on the weldability of K4951 superalloy was investigated using tungsten inert gas(TIG)welding.The as-cast K4951 superalloy samples with prefabricated U-shaped grooves of varying depths and... The impact of casting defects on the weldability of K4951 superalloy was investigated using tungsten inert gas(TIG)welding.The as-cast K4951 superalloy samples with prefabricated U-shaped grooves of varying depths and widths were TIG welded,and the microstructures,cracks morphology,and precipitated phases were analyzed using optical microscope,scanning electron microscope,transmission electron microscope,and energy dispersive X-ray spectrometer.The results reveal that the dimensions of casting defects significantly affect the weldability of K4951.Deep defects(greater than 2 mm)lead to rapid crack propagation,while wider defects can moderate the propagation process of cracks.Elemental segregation and the formation of precipitated phases,such as MC carbides,are observed in the fusion zone,contributing to welding cracks.An optimal groove aspect ratio(depth-to-width)between 0.2 and 0.5 minimizes crack formation tendency and enhances tensile strength,resulting in a mixed brittle-ductile fracture mode of joint after high-temperature tensile testing. 展开更多
关键词 casting defect K4951 TIG WELDABILITY
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Numerical Simulation and Preparation of Micro-gear via Casting Forming Using Zr-based Amorphous Alloy
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作者 Li Chunling Li Shaobing +2 位作者 Li Xiaocheng Li Chunyan Kou Shengzhong 《稀有金属材料与工程》 北大核心 2025年第6期1435-1444,共10页
A suction casting experiment was conducted on Zr_(55)Cu_(30)Al_(10)Ni_(5)(at%)amorphous alloy.Using ProCAST software,numerical simulations were performed to analyze the filling and solidification processes.The velocit... A suction casting experiment was conducted on Zr_(55)Cu_(30)Al_(10)Ni_(5)(at%)amorphous alloy.Using ProCAST software,numerical simulations were performed to analyze the filling and solidification processes.The velocity field during the filling process and the temperature field during the solidification process of the alloy melt under different process parameters were obtained.Based on the simulation results,a Zr-based amorphous alloy micro-gear was prepared via casting.The results indicate that increasing the suction casting temperature enhances the fluidity of alloy melt but induces unstable flow rate during filling,which is detrimental to complete filling.Zr-based amorphous micro-gears with a module of 0.6 mm,a tooth top diameter of 8 mm,and 10 teeth were prepared through the suction casting.X-ray diffraction and differential scanning calorimetry analyses confirm that the fabricated micro-gear exhibits characteristic amorphous structural features,demonstrating well-defined geometrical contours and satisfactory forming completeness. 展开更多
关键词 Zr-based amorphous alloy MICRO-GEAR numerical simulation CASTING
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CAST+深床反硝化滤池用于污水处理厂扩建工程
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作者 寇殿良 贝慧婷 +1 位作者 刘绍前 刘存莉 《中国给水排水》 北大核心 2025年第6期89-94,共6页
广西沿海某生活污水处理厂二期扩建规模为5×10^(4)m^(3)/d,因用地受限,故对占地相对较小的CAST、MBR、RPIR工艺进行比选,最终选择CAST+深床反硝化滤池工艺组合。针对CAST工艺除磷效果差的问题,采取了强化设计。该项目建成运营后,... 广西沿海某生活污水处理厂二期扩建规模为5×10^(4)m^(3)/d,因用地受限,故对占地相对较小的CAST、MBR、RPIR工艺进行比选,最终选择CAST+深床反硝化滤池工艺组合。针对CAST工艺除磷效果差的问题,采取了强化设计。该项目建成运营后,出水水质稳定达到一级A标准。对一期AAO氧化沟工艺和二期CAST工艺的运营情况进行了对比,在进水碳源缺乏、二级工艺不另投加碳源的条件下,CAST工艺脱氮效果比AAO氧化沟工艺好,但除磷效果比AAO氧化沟工艺差。在深床反硝化滤池的前端投加PAC和碳源强化脱氮除磷,监测结果表明,CAST+深床反硝化滤池工艺用于处理常规生活污水效果稳定,对于用地受限的污水处理厂改扩建仍是不错的工艺选择。 展开更多
关键词 CAST工艺 深床反硝化滤池 用地受限 扩容改造
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Research Status of Short Process Forming Techniques for Brazing and Soldering Materials
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作者 Dong Bowen Shi Guangyuan +4 位作者 Zhong Sujuan Dong Xian Cheng Yafang Long Weimin Zhang Guanxing 《稀有金属材料与工程》 北大核心 2025年第2期377-384,共8页
Short process forming techniques for brazing and soldering materials can shorten the process,improve product quality,and increase production efficiency,which has received much attention from welding researchers.This r... Short process forming techniques for brazing and soldering materials can shorten the process,improve product quality,and increase production efficiency,which has received much attention from welding researchers.This review mainly summarized the research reports on short process forming techniques for brazing and soldering materials.Firstly,the traditional process and its shortcomings were presented.Secondly,the latest research of short process forming technologies,such as continuous casting technique,atomization powder technique,solder ball forming technique,and rapid solidification technique,was summarized,and the traditional forming performance of several brazing and soldering materials was introduced.Finally,the current restrictions and research trends of short process forming technique for brazing and solder materials were put forward,providing theoretical guidance and reference for related research and technique development in brazing and soldering field. 展开更多
关键词 short process forming technique continuous casting atomization powder soldering ball rapid solidification amorphous filler metals
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大连某污水处理厂(一期)提标改造及工艺优化
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作者 张雨欣 范忠祥 +2 位作者 刘长远 周子豫 吴英海 《水处理技术》 北大核心 2025年第12期145-149,共5页
大连某污水处理厂(一期)为提升出水水质标准,实施了提标升级改造工程。原有污水处理工艺为CAST工艺,出水水质执行《城镇污水处理厂污染物排放标准》(GB 18918-2002)中的一级B标准。为响应国家环保法规要求,将出水标准提升至GB 18918-200... 大连某污水处理厂(一期)为提升出水水质标准,实施了提标升级改造工程。原有污水处理工艺为CAST工艺,出水水质执行《城镇污水处理厂污染物排放标准》(GB 18918-2002)中的一级B标准。为响应国家环保法规要求,将出水标准提升至GB 18918-2002一级A标准。改造工程设计规模为3.5万m^(3)/d,采用“曝气沉砂→改良AA/O→混凝(沉淀段)→过滤→紫外消毒”的主体工艺。对原有生化池进行改造,新建网格絮凝池和V型滤池等构筑物,并对污泥处理系统进行升级。改造后的污水处理系统出水水质提升,达到国家一级A标准要求。本研究可为类似项目提供参考。 展开更多
关键词 提标改造 污水处理厂 CAST AA/O 网格絮凝池 V型滤池
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珠海井岸水质净化厂CAST工艺提标扩容改造工程设计
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作者 刘羽 付朝晖 徐晓明 《中国给水排水》 北大核心 2025年第12期58-63,共6页
珠海井岸水质净化厂作为珠海西区第一座地上式污水处理厂,随着城市的发展,其水量、水质及环境景观已不能满足现状要求,亟须进行提标扩容改造。因项目用地受限,污水处理采用紧凑型CAST生化池+高效沉淀池+滤布滤池工艺,通过高加盖、建筑... 珠海井岸水质净化厂作为珠海西区第一座地上式污水处理厂,随着城市的发展,其水量、水质及环境景观已不能满足现状要求,亟须进行提标扩容改造。因项目用地受限,污水处理采用紧凑型CAST生化池+高效沉淀池+滤布滤池工艺,通过高加盖、建筑风貌改造、生态景观提升等措施将传统地上式水质净化厂打造成用地集约、功能复合的花园厂区。改造后处理规模由3.5×10^(4) m^(3)/d增至8.0×10^(4) m^(3)/d,出水水质执行《城镇污水处理厂污染物排放标准》(GB 18918—2002)一级A标准及广东省《水污染物排放限值》(DB 44/26—2001)一级标准(第二时段)的较严值,项目运行后出水各项指标均稳定达标,可为类似工程提供参考。 展开更多
关键词 地上式水质净化厂 CAST工艺 提标扩容
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Effects of infill patterns on properties of slurry extrusion-based additive manufactured shell moulds
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作者 Jiao Liu Hong-jun Liu +1 位作者 Guo-liang Su Ya-min Li 《China Foundry》 2025年第5期574-582,共9页
Investment casting shell moulds are widely applied to cast alloys, but how to efficiently form a hierarchical porous structure inside the wall is an innovation and challenge. In this research, porous shell moulds with... Investment casting shell moulds are widely applied to cast alloys, but how to efficiently form a hierarchical porous structure inside the wall is an innovation and challenge. In this research, porous shell moulds with three infill patterns(rectilinear, grid, and honeycomb) were prepared using bauxite slurry and slurry extrusionbased additive manufacturing technology, and the effects of infill patterns on the properties were evaluated. The hierarchical pores inside the wall are composed of the macropores formed by infills and the micropores among bauxite particles. Different infill patterns result in changes in distribution and shape of pores, thereby affecting the properties of the shell moulds. The honeycomb pattern has more comprehensive advantages compared to the other two infill patterns. The samples prepared with the honeycomb pattern exhibit the highest bending strength(11.62 MPa) and porosity(41.6%), as well as good heat-transfer ability, with an average shrinkage rate within 2.0%. This work provides an attractive feasibility for fabricating shell moulds with hierarchical porous walls. 展开更多
关键词 additive manufacturing slurry extrusion infill pattern casting shell mould BAUXITE investment casting
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Research progress and application prospects of die cast magnesium alloys
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作者 Mark Easton Trevor Abbott 《Journal of Magnesium and Alloys》 2025年第10期4685-4688,共4页
1.Introduction Casting accounts for over 90%of magnesium-based alloy applications with die-cast and thixomolded parts dominating.The high strength-to-weight ratio coupled with excellent fluidity,low volumetric latent ... 1.Introduction Casting accounts for over 90%of magnesium-based alloy applications with die-cast and thixomolded parts dominating.The high strength-to-weight ratio coupled with excellent fluidity,low volumetric latent heat and heat capacity,reduced cycle times,and low soldering tendencies,all make magnesium alloys excellent choices for die casting applications.Despite these advantages,in recent years,the use of magnesium in die casting applications has been declining. 展开更多
关键词 FLUIDITY high strength weight ratio heat capacity die casting die cast magnesium alloys volumetric latent heat thixomolded parts cycle times
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Microstructure and mechanical properties of a novel Nb–V–Ce multi-microalloyed low-alloy cast steel
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作者 Long Zhao Gan-chao Zhai +2 位作者 Jia-dong Wu Xiang-ru Chen Qi-jie Zhai 《Journal of Iron and Steel Research International》 2025年第10期3469-3482,共14页
A novel Nb–V–Ce multi-microalloyed low-alloy cast steel for offshore platform nodes was investigated to achieve the properties similar to X80 pipeline steel,including high yield strength and low-temperature impact e... A novel Nb–V–Ce multi-microalloyed low-alloy cast steel for offshore platform nodes was investigated to achieve the properties similar to X80 pipeline steel,including high yield strength and low-temperature impact energy.The experimental results demonstrate that the addition of elements such as Nb,V and Ce can markedly improve the strength of the low-alloy cast steel.Maintaining a constant level of elements such as Nb,V and Ce,while reducing the content of Si to 0.28 wt.%,leads to substantial enhancements in impact energy at−40℃,meeting the mechanical properties criteria of X80 pipeline steel.The excellent mechanical properties of the multi-microalloyed low-alloy cast steel result from the reason that the multi-addition of microalloying elements refines the grains and facilitates the formation of nanoprecipitates like NbC.Moreover,decreasing Si content can enhance the recovery of martensitic laths in cast steel during the tempering process,reducing stress from dislocation movement and improving plasticity. 展开更多
关键词 Nanoprecipitate MICROALLOYING Cast steel Offshore platform MICROSTRUCTURE
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Temperature fields prediction for the casting process by a conditional diffusion model
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作者 Jin-wu Kang Jing-xi Zhu Qi-chao Zhao 《China Foundry》 2025年第2期139-150,共12页
Deep learning has achieved great progress in image recognition,segmentation,semantic recognition and game theory.In this study,a latest deep learning model,a conditional diffusion model was adopted as a surrogate mode... Deep learning has achieved great progress in image recognition,segmentation,semantic recognition and game theory.In this study,a latest deep learning model,a conditional diffusion model was adopted as a surrogate model to predict the heat transfer during the casting process instead of numerical simulation.The conditional diffusion model was established and trained with the geometry shapes,initial temperature fields and temperature fields at t_(i) as the condition and random noise sampled from standard normal distribution as the input.The output was the temperature field at t_(i+1).Therefore,the temperature field at t_(i+1)can be predicted as the temperature field at t_(i) is known,and the continuous temperature fields of all the time steps can be predicted based on the initial temperature field of an arbitrary 2D geometry.A training set with 3022D shapes and their simulated temperature fields at different time steps was established.The accuracy for the temperature field for a single time step reaches 97.7%,and that for continuous time steps reaches 69.1%with the main error actually existing in the sand mold.The effect of geometry shape and initial temperature field on the prediction accuracy was investigated,the former achieves better result than the latter because the former can identify casting,mold and chill by different colors in the input images.The diffusion model has proved the potential as a surrogate model for numerical simulation of the casting process. 展开更多
关键词 diffusion model U-Net CASTING simulation heat transfer
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Lightweight design and manufacture of die casting magnesium alloy seat frame
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作者 Jian Yang Kangle Wang +3 位作者 Qin Yang Jinsheng Zhang Tiegang Hu Bo Liu 《Journal of Magnesium and Alloys》 2025年第10期4817-4824,共8页
This study presents the development of a Magnesium Alloy Seat Frame(MASF),supported by case studies from automotive original equipment manufacturers.The process covers integrated design,simulation,manufacturing,and te... This study presents the development of a Magnesium Alloy Seat Frame(MASF),supported by case studies from automotive original equipment manufacturers.The process covers integrated design,simulation,manufacturing,and testing,aiming to boost industry confidence in Mg alloy applications.A novel structural design is developed that integrates the headrest with the backrest,achieving a balance between lightweight performance and safety.Structural optimization is guided by stress–strain simulations under diverse conditions within a complete forward development process.Casting simulations are conducted to analyze process characteristics,resulting in a verified MASF yield rate exceeding 90%.The final 9.88 kg MASF represents a 24.6%(3.23 kg)weight reduction versus a steel seat.This research contributes to advancements in defect control technology for large die casting magnesium alloy parts and has broad implications for their application in automotive manufacturing. 展开更多
关键词 MAGNESIUM Seat frame Forward design Die casting Lightweighting
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Influence of Tin addition on microstructure,mechanical,and tribological properties of magnesium matrix
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作者 John Iruthaya Raj Manuvel Senthil Murugan Subramanian +1 位作者 Raja Venkatesan Jebapriya Mani 《China Foundry》 2025年第6期664-672,共9页
In this study,the effect of Tin(Sn)addition on the microstructure,mechanical properties,and wear resistance of pure magnesium(Mg)was examined.Mg-Sn alloys were synthesized using stir casting technique with Sn concentr... In this study,the effect of Tin(Sn)addition on the microstructure,mechanical properties,and wear resistance of pure magnesium(Mg)was examined.Mg-Sn alloys were synthesized using stir casting technique with Sn concentrations of 2.5%,5%,and 7.5% by weight.The specimens were prepared as per ASTM standards for their evaluation.Higher Sn concentrations result in a reduced volume fraction of the eutectic phase,while Mg_(2)Sn precipitates are observed in alloys with 5% or more Sn.Scanning electron microscopy(SEM)analysis of the Mg-7.5wt.%Sn alloy reveals the presence of Mg(OH)_(2),with X-ray diffraction(XRD)confirming an oxygen content of 18% by weight.The addition of Sn minimizes casting porosity,enhancing the quality of the alloys.The findings demonstrate a positive correlation between increasing Sn content and enhanced strength and wear resistance.The Mg-7.5wt.%Sn alloy exhibits significantly enhanced tensile properties attributed to grain refinement and the formation of well-defined grain boundaries compared to alloys with lower Sn additions(2.5% and 5%),although a slight reduction in microhardness is observed.Tribological evaluation indicates reduced wear and friction,suggesting better surface performance.This research underscores the complex interplay between Sn content,microstructural evolution,and the resulting mechanical and tribological performance of Mg-Sn alloys. 展开更多
关键词 Sn element MAGNESIUM stir casting MICROSTRUCTURE tensile strength
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Simulation study on integrated bottom car body formation by high pressure die casting with a dual injection system
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作者 Rong Xiao Jing-guo Wang +6 位作者 Shao-xing Meng Wei-dong Mao Li-geng Yang Jin Zhang Lei Song Wan-tong Chen Wen-bo Yu 《China Foundry》 2025年第4期363-373,共11页
This study investigates the formation feasibility of the integrated bottom car body components with dual die casting injection molding technology.During the production of a die-cast super-large one-piece body part wei... This study investigates the formation feasibility of the integrated bottom car body components with dual die casting injection molding technology.During the production of a die-cast super-large one-piece body part weighing over 10,000 t,a thorough comparison and investigation were conducted on the arising issues,using both single and double injection systems.Particular attention was given to meticulously discussing the die casting filling problems and microstructural defects that originated from the filling process.The research findings indicate that the implementation of a double injection system can significantly minimize cold shuts and reduce the solidification time.The effectiveness of this die casting technique was further confirmed by the production of high-quality castings using a scaled model that replicated real casting conditions at a 1:3 ratio,thereby maintaining a one-to-one correspondence in essential aspects.This successful study offers both theoretical insights and practical applications for the production of integrated bottom car bodies utilizing die casting in conjunction with a dual injection system. 展开更多
关键词 intergrated bottom car body die casting(megacasting) dual injection system scaled model die casting filling problems
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Investigation of clinical outcomes in conservative management of hook fractures:Commentary on recent findings
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作者 Li-Hu Ding Pan-Feng Wu Nian-Zhe Sun 《World Journal of Orthopedics》 2025年第5期1-4,共4页
This editorial critically evaluates the landmark study by Tanaka and Yoshii,which demonstrated a 100%union rate with conservative management of hamate hook fractures,challenging the historical preference for surgical ... This editorial critically evaluates the landmark study by Tanaka and Yoshii,which demonstrated a 100%union rate with conservative management of hamate hook fractures,challenging the historical preference for surgical intervention.In contrast to Scheufle et al’s report of 90%-100%failure rates with early surgical approaches,Tanaka and Yoshii’s protocol achieved universal healing despite delayed diagnoses in 25%of cases.Central to this success is the systematic inte-gration of high-resolution computed tomography for early diagnosis and dynamic monitoring of trabecular bone regeneration,significantly reducing missed dia-gnoses and guiding personalized immobilization timelines.The patient-centered strategy—allowing temporary splint removal during low-risk activities—balanced fracture stability with joint mobility preservation,avoiding post-treatment stiff-ness.However,limitations such as small sample size(n=16),selection bias,and insufficient long-term functional data(e.g.,grip strength,return-to-sport metrics)underscore the need for comparative trials.Emerging trends,including adjunct therapies like low-intensity pulsed ultrasound and biologics(e.g.,teriparatide),are proposed to accelerate healing while minimizing immobilization risks.This work redefines conservative fracture management paradigms,emphasizing in-novation without compromising efficacy.Overall,this assessment deepens our understanding of the conservative management of hook fractures and provides evidence-based insights for improved clinical decision-making. 展开更多
关键词 Hook fracture Conservative treatment Cast immobilization Early diagnosis Rehabilitation
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