Background： Intake of colostrum after birth is essential to stimulate intestinal growth and function, and to provide systemic immunological protection via absorption of Immunoglobulin G （IgG）. The birth order and w...Background： Intake of colostrum after birth is essential to stimulate intestinal growth and function, and to provide systemic immunological protection via absorption of Immunoglobulin G （IgG）. The birth order and weight of 745 piglets （from 75 litters） were recorded during a one-week period of farrowing. Only pigs weighing greater than 0.68 kg birth weight were chosen for the trial. Sow colostrum was collected during parturition, and piglets were bled between 48 and 72 hours post-birth. Piglet serum IgG and colostral IgG concentrations were determined by radial immunodiffusion. Results： Sow parity had a significant （P 〈 0.001） effect on sow colostral IgG concentration, being 5% higher in multiparous females. Sow colostral IgG concentration explained 6% and piglet birth order accounted for another 4% of the variation observed in piglet serum IgG concentration （P 〈 0.05）; however, birth weight had no detectable effect. Piglet serum IgG concentration had both a linear （P 〈 0.05） and quadratic effect （P 〈 0.05） on % survival. Piglets with 1,000 mg/dl serum IgG or less （n=24） had a 67% survival; whereas, piglets with IgG concentrations between 2250 to 2500 mg/dl （n=247） had a 91% survival. Birth order had no detectable effect on survival, but birth weight had a positive linear effect （P 〈 0.05）. Piglets weighing 0.9 kg （n = 107） at birth had a 68% survival rate, and those weighing 1.6 kg （n = 158） had an 89% survival. Conclusion： We found that the combination of sow colostrum IgG concentration and birth order can account for 10% of the variation of piglet serum IgG concentration and that piglets with less than 1,000 mg/dl IgG serum concentration and weight of 0.9 kg at birth had low survival rate when compared to their larger siblings. The effective management of colostrum uptake in neonatal piglets in the first 24 hrs post-birth may potentially improve survival from birth to weaning.展开更多
目的探讨出生顺序对双胎早产儿并发症的影响及其原因。方法选取2020年1月—2020年12月嘉兴市妇幼保健院新生儿科收治的胎龄<35周的双胎早产儿42对为研究对象,按照出生顺序分为先出生组和后出生组,配对分析比较组间基线资料、并发症...目的探讨出生顺序对双胎早产儿并发症的影响及其原因。方法选取2020年1月—2020年12月嘉兴市妇幼保健院新生儿科收治的胎龄<35周的双胎早产儿42对为研究对象,按照出生顺序分为先出生组和后出生组,配对分析比较组间基线资料、并发症发病率、呼吸支持治疗情况、Apgar评分及血清维生素水平。结果先后娩出的双胎早产儿间呼吸窘迫综合征(RDS)发病率(14.3%vs.40.0%,P<0.05)、呼吸衰竭发病率(2.4%vs.16.7%,P<0.05)、肺泡表面活性物质(PS)使用率(11.9%vs.28.6%,P<0.05)存在显著差异。后出生组的1 min、5 min及10 min Apgar评分低于先出生组,差异有统计学意义(P<0.05);而组间血清维生素A、D及E水平无显著差异。结论对胎龄<35周的双胎早产儿,后娩出者发生RDS、呼吸衰竭、使用PS的风险更高,其原因可能是与后娩出者更易窒息有关,而与新生儿本身血清维生素A、D及E水平无关。展开更多
文摘Background： Intake of colostrum after birth is essential to stimulate intestinal growth and function, and to provide systemic immunological protection via absorption of Immunoglobulin G （IgG）. The birth order and weight of 745 piglets （from 75 litters） were recorded during a one-week period of farrowing. Only pigs weighing greater than 0.68 kg birth weight were chosen for the trial. Sow colostrum was collected during parturition, and piglets were bled between 48 and 72 hours post-birth. Piglet serum IgG and colostral IgG concentrations were determined by radial immunodiffusion. Results： Sow parity had a significant （P 〈 0.001） effect on sow colostral IgG concentration, being 5% higher in multiparous females. Sow colostral IgG concentration explained 6% and piglet birth order accounted for another 4% of the variation observed in piglet serum IgG concentration （P 〈 0.05）; however, birth weight had no detectable effect. Piglet serum IgG concentration had both a linear （P 〈 0.05） and quadratic effect （P 〈 0.05） on % survival. Piglets with 1,000 mg/dl serum IgG or less （n=24） had a 67% survival; whereas, piglets with IgG concentrations between 2250 to 2500 mg/dl （n=247） had a 91% survival. Birth order had no detectable effect on survival, but birth weight had a positive linear effect （P 〈 0.05）. Piglets weighing 0.9 kg （n = 107） at birth had a 68% survival rate, and those weighing 1.6 kg （n = 158） had an 89% survival. Conclusion： We found that the combination of sow colostrum IgG concentration and birth order can account for 10% of the variation of piglet serum IgG concentration and that piglets with less than 1,000 mg/dl IgG serum concentration and weight of 0.9 kg at birth had low survival rate when compared to their larger siblings. The effective management of colostrum uptake in neonatal piglets in the first 24 hrs post-birth may potentially improve survival from birth to weaning.
文摘目的探讨出生顺序对双胎早产儿并发症的影响及其原因。方法选取2020年1月—2020年12月嘉兴市妇幼保健院新生儿科收治的胎龄<35周的双胎早产儿42对为研究对象,按照出生顺序分为先出生组和后出生组,配对分析比较组间基线资料、并发症发病率、呼吸支持治疗情况、Apgar评分及血清维生素水平。结果先后娩出的双胎早产儿间呼吸窘迫综合征(RDS)发病率(14.3%vs.40.0%,P<0.05)、呼吸衰竭发病率(2.4%vs.16.7%,P<0.05)、肺泡表面活性物质(PS)使用率(11.9%vs.28.6%,P<0.05)存在显著差异。后出生组的1 min、5 min及10 min Apgar评分低于先出生组,差异有统计学意义(P<0.05);而组间血清维生素A、D及E水平无显著差异。结论对胎龄<35周的双胎早产儿,后娩出者发生RDS、呼吸衰竭、使用PS的风险更高,其原因可能是与后娩出者更易窒息有关,而与新生儿本身血清维生素A、D及E水平无关。
