This work is concerned with the application of a redefined set of extended uniform cubic B-spline(RECBS)functions for the numerical treatment of time-fractional Telegraph equation.The presented technique engages finit...This work is concerned with the application of a redefined set of extended uniform cubic B-spline(RECBS)functions for the numerical treatment of time-fractional Telegraph equation.The presented technique engages finite difference formulation for discretizing the Caputo time-fractional derivatives and RECBS functions to interpolate the solution curve along the spatial grid.Stability analysis of the scheme is provided to ensure that the errors do not amplify during the execution of the numerical procedure.The derivation of uniform convergence has also been presented.Some computational experiments are executed to verify the theoretical considerations.Numerical results are compared with the existing schemes and it is concluded that the present scheme returns superior outcomes on the topic.展开更多
The global characteristics of a fingerprint image such as the ridge shape and ridge topology are often ignored in most automatic fingerprint verification system.In this paper,a new representative method based on B-Spl...The global characteristics of a fingerprint image such as the ridge shape and ridge topology are often ignored in most automatic fingerprint verification system.In this paper,a new representative method based on B-Spline curve is proposed to address this problem.The resultant B-Spline curves can represent the global characteristics completely and the curves are analyzable and precise.An algorithm is also proposed to extract the curves from the fingerprint image.In addition to preserve the most information of the fingerprint image,the knot-points number of the B-Spline curve is reduced to minimum in this algorithm.At the same time,the influence of the fingerprint image noise is discussed.In the end,an example is given to demonstrate the effectiveness of the representation method.Key words fingerprint matching-B-spline interpolation-knots detection-parameterization-boundary condition CLC number TP 391.41 Foundation item:Supported by the National Natural Science Foundation of China(90200400)and Wuhan Technology Committee(991009185G)Biography:Ruan Ke(1979-),male,Master candidate,research direction:digital image processing.展开更多
In this study, we use B-spline functions to solve the linear and nonlinear special systems of differential equations associated with the category of obstacle, unilateral, and contact problems. The problem can easily c...In this study, we use B-spline functions to solve the linear and nonlinear special systems of differential equations associated with the category of obstacle, unilateral, and contact problems. The problem can easily convert to an optimal control problem. Then a convergent approximate solution is constructed such that the exact boundary conditions are satisfied. The numerical examples and computational results illustrate and guarantee a higher accuracy for this technique.展开更多
Gauss radial basis functions(GRBF)are frequently employed in data fitting and machine learning.Their linear independence property can theoretically guarantee the avoidance of data redundancy.In this paper,one of the m...Gauss radial basis functions(GRBF)are frequently employed in data fitting and machine learning.Their linear independence property can theoretically guarantee the avoidance of data redundancy.In this paper,one of the main contributions is proving this property using linear algebra instead of profound knowledge.This makes it easy to read and understand this fundamental fact.The proof of linear independence of a set of Gauss functions relies on the constructing method for one-dimensional space and on the deducing method for higher dimensions.Additionally,under the condition of preserving the same moments between the original function and interpolating function,both the interpolating existence and uniqueness are proven for GRBF in one-dimensional space.The final work demonstrates the application of the GRBF method to locate lunar olivine.By combining preprocessed data using GRBF with the removing envelope curve method,a program is created to find the position of lunar olivine based on spectrum data,and the numerical experiment shows that it is an effective scheme.展开更多
Spatial memory is crucial for survival within external surroundings and wild environments.The hippocampus,a critical hub for spatial learning and memory formation,has received extensive investigations on how neuromodu...Spatial memory is crucial for survival within external surroundings and wild environments.The hippocampus,a critical hub for spatial learning and memory formation,has received extensive investigations on how neuromodulators shape its functions(Teixeira et al.,2018;Zhang et al.,2024).However,the landscape of neuromodulations in the hippocampal system remains poorly understood because most studies focus on classical monoamine neuromodulators,such as acetylcholine,serotonin,dopamine,and noradrenaline.The neuropeptides,comprising the most abundant neuromodulators in the central nervous system,play a pivotal role in neural information processing in the hippocampal system.Cholecystokinin(CCK),one of the most abundant neuropeptides,has been implicated in regulating various physiological and neurobiological statuses(Chen et al.,2019).CCK-A receptor(CCK-AR)and CCK-B receptors(CCK-BR)are two key receptors mediating the biological functions of CCK,both of which belong to class-A sevenfold transmembrane G protein-coupled receptors(Nishimura et al.,2015).CCK-AR preferentially reacts to sulfated CCK,whereas CCK-BR binds both CCK and gastrin with similar affinities(Ding et al.,2022).The expression patterns of CCK-AR and CCK-BR are distinct,implying that CCK has various functions in target regions.For instance,CCK-AR is widely expressed in the GI and brain subregions and is hence implicated in the control of digestive function and satiety regulation.Conversely,CCK-BR is abundantly and widely distributed in the central nervous system,which majorly regulates anxiety,learning,and memory(Ding et al.,2022).However,the roles of endogenous CCK and CCK receptors in regulating hippocampal function at electrophysiological and behavioral levels have received less attention.展开更多
Five-valued Boolean functions play an important role in the design of symmetric cryptography.While the design and properties of single-output almost optimal five-valued spectra Boolean functions have been extensively ...Five-valued Boolean functions play an important role in the design of symmetric cryptography.While the design and properties of single-output almost optimal five-valued spectra Boolean functions have been extensively studied over the past few decades,there has been limited research on the construction of almost optimal five-valued spectra vectorial Boolean functions.In this paper,we present a construction method for even-variable 2-output almost optimal five-valued spectra balanced Boolean functions,whose Walsh spectra values belong to the set{0,±2^(n/2),±2^(n/2+1)},at the same time,we discuss the existence of sufficient conditions in the construction.Additionally,this paper presents a novel construction method for balanced single-output Boolean functions with even variables featuring a special five-valued spectral structure,whose Walsh spectra values are constrained to the set{0,±2^(n/2),±3·2^(n/2)}.These functions provide new canonical examples for the study of Boolean function spectral theory.展开更多
The Red Sea-Gulf of Suez-Cairo-Alexandria Clysmic-Trend in northern Egypt is the main earthquake zone in the country,with a moderate-to-high seismic hazard and a history of significant earthquakes caused by rifting an...The Red Sea-Gulf of Suez-Cairo-Alexandria Clysmic-Trend in northern Egypt is the main earthquake zone in the country,with a moderate-to-high seismic hazard and a history of significant earthquakes caused by rifting and active faulting.To improve our understanding of the tectonic and seismic processes in this area,more comprehensive imaging of the crustal structure is required.This can be achieved by increasing the number of receiver functions(RFs)recorded by the seismic stations in northern Egypt and the southeastern Mediterranean.Data handling and processing should also be automated to increase process efficiency.In this study,we developed a capsule neural network for automated selection of RFs.The model was trained on a dataset containing RFs(both selected and unselected)from five broadband stations in northern Egypt.Stations SLM,SIWA,KOT,NBNS,and NKL are located in the unstable shelf region of Egypt,where limited knowledge of the deep crustal structure is available.The proposed capsule neural network achieved an average precision of 80%on the test set.The automated selection of RFs using a capsule neural network has the potential to significantly improve the efficiency and accuracy of RF analysis,as demonstrated by the stacking test.This could lead to a better understanding of crustal structure and tectonic processes in northern Egypt and the southeastern Mediterranean.展开更多
This paper attempts to form a bridge between a sum of the divisors function and the gamma function, proposing a novel approach that could have significant implications for classical problems in number theory, specific...This paper attempts to form a bridge between a sum of the divisors function and the gamma function, proposing a novel approach that could have significant implications for classical problems in number theory, specifically the Robin inequality and the Riemann hypothesis. The exploration of using invariant properties of these functions to derive insights into twin primes and sequential primes is a potentially innovative concept that deserves careful consideration by the mathematical community.展开更多
Lactylation is one of the post-translational modifications of proteins,a process in which lactyl residues bind to the lysine residues of proteins.This modification can alter the structure,stability,and function of pro...Lactylation is one of the post-translational modifications of proteins,a process in which lactyl residues bind to the lysine residues of proteins.This modification can alter the structure,stability,and function of proteins,which in turn regulates cellular metabolism,aging,and the onset of disease.This review classifies proteins with lactylation effects into histones and non-histone proteins and analyzes their functional roles when lactylation occurs.The in-depth exploration of lactylation is still in its infancy,and many aspects of its regulation,functional significance and therapeutic potential need to be further explored.展开更多
In the paper,a class of functions with bounded turnings involving cardioid domain,are studied in the region of the unit disc.The bounds of|a_(5)|,|a_(6)|,|a_(7)|and the fourth Hankel determinant are obtained,which are...In the paper,a class of functions with bounded turnings involving cardioid domain,are studied in the region of the unit disc.The bounds of|a_(5)|,|a_(6)|,|a_(7)|and the fourth Hankel determinant are obtained,which are more accurate than those obtained by Srivastava.展开更多
For the new subclass B of the bi-univalent functions constructed with the help of the(u,v)-Chebyshev polynomials of the second type,we get estimates for the first two initial coefficients and upper bounds of the Feket...For the new subclass B of the bi-univalent functions constructed with the help of the(u,v)-Chebyshev polynomials of the second type,we get estimates for the first two initial coefficients and upper bounds of the Fekete-Szeg o functional.展开更多
In this paper,we study asymptotic power series of the composition f(x)=h(g(x)),where g(x)=∑_(n=0)^(∞)b_(n)x^(-n),b_(n)∈R,and h is a given elementary function.The asymptotic expansions have been obtained for the com...In this paper,we study asymptotic power series of the composition f(x)=h(g(x)),where g(x)=∑_(n=0)^(∞)b_(n)x^(-n),b_(n)∈R,and h is a given elementary function.The asymptotic expansions have been obtained for the composition with an exponential or logarithmic function.Using the re-cursive method,we present the asymptotic expansions for the composition with seven trigonometric functions,respectively.As an application,the asymptotic expansions of roots of some equations are given.Computational results show that our recursive formula is more efficient than the method of Lagrange's inverse theorem.展开更多
The following article has been retracted due to the investigation of complaints received against it. The Editorial Board found that substantial portions of the text came from other published papers. The scientific com...The following article has been retracted due to the investigation of complaints received against it. The Editorial Board found that substantial portions of the text came from other published papers. The scientific community takes a very strong view on this matter, and the Health treats all unethical behavior such as plagiarism seriously. This paper published in Vol.3 No. 4, 334-339, 2012, has been removed from this site.展开更多
Intracellular polymerization is an emerging field,showcasing high diversity and efficiency of chemistry.Motivated by the principles of natural biomolecular synthesis,polymerization within living cells is believed to b...Intracellular polymerization is an emerging field,showcasing high diversity and efficiency of chemistry.Motivated by the principles of natural biomolecular synthesis,polymerization within living cells is believed to be a powerful and versatile tool to modulate cell behavior.In this review,we summarized recent advances and future trends in the field of intracellular polymerization,specifically focusing on covalent and supramolecular polymerization.This discussion comprehensively covers the diverse chemical designs,reaction mechanisms,responsive features,and functional applications.Furthermore,we also clarified the connection between preliminary design of polymer synthesis and their subsequent biological applications.We hope this review will serve as an innovative platform for chemists and biologists to regulate biological functions in practical applications and clinical trials.展开更多
Objectives:This prospective cohort study examined the change trajectories of cognitive and physical functions of individuals with motoric cognitive risk(MCR)syndrome,as well as the longitudinal associations between MC...Objectives:This prospective cohort study examined the change trajectories of cognitive and physical functions of individuals with motoric cognitive risk(MCR)syndrome,as well as the longitudinal associations between MCR syndrome and changes in cognitive and physical functions,to provide a new perspective on preventing dementia.Methods:Participants were selected from the China Health and Retirement Longitudinal Study(CHARLS).Demographic characteristics,health status,and lifestyle variables were assessed in 2011.MCR syndrome was defined as the presence of subjective cognitive complaints and objective slow gait,with preserved activities of daily living and absence of dementia,and assessed in 2011.Cognitive function,including orientation,attention and calculation,episodic memory,and visuospatial ability,was measured from 2011 to 2018.Physical function,including grip strength,balance ability,and repeated chair stand tests,was measured from 2011 to 2015.Generalized estimating equation was employed to analyze the longitudinal associations between MCR syndrome in 2011 and changes in cognitive functions over 7 years and physical functions over 4 years.Results:Among 4,217 participants,475 had MCR syndrome in 2011.Both participants with MCR syndrome and those without exhibited a decline in both cognitive and physical function over 7 years and 4 years of follow-up,except for fluctuations in visuospatial ability.Non-MCR syndrome participants demonstrated significantly better overall cognitive function in 2018 compared to 2011(Group×Time:B=0.44,P=0.035)than those in the MCR syndrome group.However,participants with non-MCR syndrome demonstrated significantly worse visuospatial ability in 2013(Group×time:B=−0.44,P=0.002)and 2018(Group×time:B=−0.34,P=0.016)compared to those in the MCR syndrome group.Non-MCR syndrome participants demonstrated significantly better performance in repeated chair stand tests in 2013(Group×time:B=0.31,P<0.001)and 2015(Group×time:B=0.37,P<0.001)compared to those in the MCR syndrome group in 2011.Conclusions:Older adults with MCR syndrome experience worse overall cognitive and physical function performance,especially in repeated chair stand tests,than individuals without MCR syndrome over 7-year and 4-year follow-up periods.It is suggested that future interventional studies will target both physical and cognitive functions in MCR syndrome individuals,providing insights for the prevention of dementia.展开更多
In this paper,we study normal families of meromorphic functions.By using the idea in[16],we obtain some normality criteria for families of meromorphic functions concerning the wandering multiple functions,which extend...In this paper,we study normal families of meromorphic functions.By using the idea in[16],we obtain some normality criteria for families of meromorphic functions concerning the wandering multiple functions,which extend and improve the well-known Montel's criterion,Bloch-Valiron's theorem,and the related results due to Carathéodory,and Grahl-Nevo et al..展开更多
Accurately revealing the spatial heterogeneity in the trade-offs and synergies of land use functions(LUFs)and their driving factors is imperative for advancing sustainable land utilization and optimizing land use plan...Accurately revealing the spatial heterogeneity in the trade-offs and synergies of land use functions(LUFs)and their driving factors is imperative for advancing sustainable land utilization and optimizing land use planning.This is especially critical for ecologically vulnerable inland river basins in arid regions.However,existing methods struggle to effectively capture complex nonlinear interactions among environmental factors and their multifaceted relationships with trade-offs and synergies of LUFs,especially for the inland river basins in arid regions.Consequently,this study focused on the middle reaches of the Heihe River Basin(MHRB),an arid inland river basin in northwestern China.Using land use,socioeconomic,meteorological,and hydrological data from 2000 to 2020,we analyzed the spatiotemporal patterns of LUFs and their trade-off and synergy relationships from the perspective of production,living,ecological functions.Additionally,we employed an integrated Extreme Gradient Boosting(XGBoost)-SHapley Additive exPlanations(SHAP)framework to investigate the environmental factors influencing the spatial heterogeneity in the trade-offs and synergies of LUFs.Our findings reveal that from 2000 to 2020,the production,living,and ecological functions of land use within the MHRB exhibited an increasing trend,demonstrating a distinct spatial pattern of''high in the southwest and low in the northeast''.Significant spatial heterogeneity defined the trade-off and synergistic relationships,with trade-offs dominating human activity-intensive oasis areas,while synergies prevailed in other areas.During the study period,synergistic relationships between production and living functions and between production and ecological functions were relatively robust,whereas synergies in living-ecological functions remained weaker.Natural factors(digital elevation model(DEM),annual mean temperature,Normalized Difference Vegetation Index(NDVI),and annual precipitation)emerged as the primary factors driving the trade-offs and synergies of LUFs,followed by socioeconomic factors(population density,Gross Domestic Product(GDP),and land use intensity),while distance factors(distance to water bodies,distance to residential areas,and distance to roads)exerted minimal influence.Notably,the interactions among NDVI,annual mean temperature,DEM,and land use intensity exerted the most substantial impacts on the relationships among LUFs.This study provides novel perspectives and methodologies for unraveling the mechanisms underlying the spatial heterogeneity in the trade-offs and synergies of LUFs,offering scientific insights to inform regional land use planning and sustainable natural resource management in inland river basins in arid regions.展开更多
In this paper,we obtain a normality criterion for families of meromorphic functions concerning‘wandering’shared functions,which generalizes and improves Montel’s criterion and the related results due to Schwick,Xu-...In this paper,we obtain a normality criterion for families of meromorphic functions concerning‘wandering’shared functions,which generalizes and improves Montel’s criterion and the related results due to Schwick,Xu-Fang,Xu-Qiu,and Grahl-Nevo.Also,a normality relationship between two families is given.展开更多
In this paper,we establish characterizations of α-Bloch functions and little α-Bloch functions on the unit ball as well as the unit polydisk of C^(m),which generalize and improve results of Aulaskari-Lappan,Minda,Au...In this paper,we establish characterizations of α-Bloch functions and little α-Bloch functions on the unit ball as well as the unit polydisk of C^(m),which generalize and improve results of Aulaskari-Lappan,Minda,Aulaskari-Wulan,and Wu.Some examples are also given to complement our theory.展开更多
The fourth-order B spline wavelet scaling functions are used to solve the two-dimensional unsteady diffusion equation. The calculations from a case history indicate that the method provides high accuracy and the compu...The fourth-order B spline wavelet scaling functions are used to solve the two-dimensional unsteady diffusion equation. The calculations from a case history indicate that the method provides high accuracy and the computational efficiency is enhanced due to the small matrix derived from this method.The respective features of 3-spline wavelet scaling functions,4-spline wavelet scaling functions and quasi-wavelet used to solve the two-dimensional unsteady diffusion equation are compared. The proposed method has potential applications in many fields including marine science.展开更多
文摘This work is concerned with the application of a redefined set of extended uniform cubic B-spline(RECBS)functions for the numerical treatment of time-fractional Telegraph equation.The presented technique engages finite difference formulation for discretizing the Caputo time-fractional derivatives and RECBS functions to interpolate the solution curve along the spatial grid.Stability analysis of the scheme is provided to ensure that the errors do not amplify during the execution of the numerical procedure.The derivation of uniform convergence has also been presented.Some computational experiments are executed to verify the theoretical considerations.Numerical results are compared with the existing schemes and it is concluded that the present scheme returns superior outcomes on the topic.
基金Foundation itemSupported by the NationalNatural Science Foun-dation of China(90200400)Wuhan Technology Committee(991009185G)
文摘The global characteristics of a fingerprint image such as the ridge shape and ridge topology are often ignored in most automatic fingerprint verification system.In this paper,a new representative method based on B-Spline curve is proposed to address this problem.The resultant B-Spline curves can represent the global characteristics completely and the curves are analyzable and precise.An algorithm is also proposed to extract the curves from the fingerprint image.In addition to preserve the most information of the fingerprint image,the knot-points number of the B-Spline curve is reduced to minimum in this algorithm.At the same time,the influence of the fingerprint image noise is discussed.In the end,an example is given to demonstrate the effectiveness of the representation method.Key words fingerprint matching-B-spline interpolation-knots detection-parameterization-boundary condition CLC number TP 391.41 Foundation item:Supported by the National Natural Science Foundation of China(90200400)and Wuhan Technology Committee(991009185G)Biography:Ruan Ke(1979-),male,Master candidate,research direction:digital image processing.
文摘In this study, we use B-spline functions to solve the linear and nonlinear special systems of differential equations associated with the category of obstacle, unilateral, and contact problems. The problem can easily convert to an optimal control problem. Then a convergent approximate solution is constructed such that the exact boundary conditions are satisfied. The numerical examples and computational results illustrate and guarantee a higher accuracy for this technique.
基金Supported by the National Basic Research Program of China(2012CB025904)Zhengzhou Shengda University of Economics,Business and Management(SD-YB2025085)。
文摘Gauss radial basis functions(GRBF)are frequently employed in data fitting and machine learning.Their linear independence property can theoretically guarantee the avoidance of data redundancy.In this paper,one of the main contributions is proving this property using linear algebra instead of profound knowledge.This makes it easy to read and understand this fundamental fact.The proof of linear independence of a set of Gauss functions relies on the constructing method for one-dimensional space and on the deducing method for higher dimensions.Additionally,under the condition of preserving the same moments between the original function and interpolating function,both the interpolating existence and uniqueness are proven for GRBF in one-dimensional space.The final work demonstrates the application of the GRBF method to locate lunar olivine.By combining preprocessed data using GRBF with the removing envelope curve method,a program is created to find the position of lunar olivine based on spectrum data,and the numerical experiment shows that it is an effective scheme.
文摘Spatial memory is crucial for survival within external surroundings and wild environments.The hippocampus,a critical hub for spatial learning and memory formation,has received extensive investigations on how neuromodulators shape its functions(Teixeira et al.,2018;Zhang et al.,2024).However,the landscape of neuromodulations in the hippocampal system remains poorly understood because most studies focus on classical monoamine neuromodulators,such as acetylcholine,serotonin,dopamine,and noradrenaline.The neuropeptides,comprising the most abundant neuromodulators in the central nervous system,play a pivotal role in neural information processing in the hippocampal system.Cholecystokinin(CCK),one of the most abundant neuropeptides,has been implicated in regulating various physiological and neurobiological statuses(Chen et al.,2019).CCK-A receptor(CCK-AR)and CCK-B receptors(CCK-BR)are two key receptors mediating the biological functions of CCK,both of which belong to class-A sevenfold transmembrane G protein-coupled receptors(Nishimura et al.,2015).CCK-AR preferentially reacts to sulfated CCK,whereas CCK-BR binds both CCK and gastrin with similar affinities(Ding et al.,2022).The expression patterns of CCK-AR and CCK-BR are distinct,implying that CCK has various functions in target regions.For instance,CCK-AR is widely expressed in the GI and brain subregions and is hence implicated in the control of digestive function and satiety regulation.Conversely,CCK-BR is abundantly and widely distributed in the central nervous system,which majorly regulates anxiety,learning,and memory(Ding et al.,2022).However,the roles of endogenous CCK and CCK receptors in regulating hippocampal function at electrophysiological and behavioral levels have received less attention.
基金National Natural Science Foundation of China(62272360)。
文摘Five-valued Boolean functions play an important role in the design of symmetric cryptography.While the design and properties of single-output almost optimal five-valued spectra Boolean functions have been extensively studied over the past few decades,there has been limited research on the construction of almost optimal five-valued spectra vectorial Boolean functions.In this paper,we present a construction method for even-variable 2-output almost optimal five-valued spectra balanced Boolean functions,whose Walsh spectra values belong to the set{0,±2^(n/2),±2^(n/2+1)},at the same time,we discuss the existence of sufficient conditions in the construction.Additionally,this paper presents a novel construction method for balanced single-output Boolean functions with even variables featuring a special five-valued spectral structure,whose Walsh spectra values are constrained to the set{0,±2^(n/2),±3·2^(n/2)}.These functions provide new canonical examples for the study of Boolean function spectral theory.
文摘The Red Sea-Gulf of Suez-Cairo-Alexandria Clysmic-Trend in northern Egypt is the main earthquake zone in the country,with a moderate-to-high seismic hazard and a history of significant earthquakes caused by rifting and active faulting.To improve our understanding of the tectonic and seismic processes in this area,more comprehensive imaging of the crustal structure is required.This can be achieved by increasing the number of receiver functions(RFs)recorded by the seismic stations in northern Egypt and the southeastern Mediterranean.Data handling and processing should also be automated to increase process efficiency.In this study,we developed a capsule neural network for automated selection of RFs.The model was trained on a dataset containing RFs(both selected and unselected)from five broadband stations in northern Egypt.Stations SLM,SIWA,KOT,NBNS,and NKL are located in the unstable shelf region of Egypt,where limited knowledge of the deep crustal structure is available.The proposed capsule neural network achieved an average precision of 80%on the test set.The automated selection of RFs using a capsule neural network has the potential to significantly improve the efficiency and accuracy of RF analysis,as demonstrated by the stacking test.This could lead to a better understanding of crustal structure and tectonic processes in northern Egypt and the southeastern Mediterranean.
文摘This paper attempts to form a bridge between a sum of the divisors function and the gamma function, proposing a novel approach that could have significant implications for classical problems in number theory, specifically the Robin inequality and the Riemann hypothesis. The exploration of using invariant properties of these functions to derive insights into twin primes and sequential primes is a potentially innovative concept that deserves careful consideration by the mathematical community.
基金supported by the Natural Science Foundation of Guangdong Province(No.2024A1515010605,2022A1515140034)Discipline Construction Project of Guangdong Medical University(No.4SG24007G,4SG22302P)+1 种基金Medical Scientific Research Fund of Guangdong Province(No.B2024193)Dongguan Social Development and Scientific Technology Project,China(No.20231800936562).
文摘Lactylation is one of the post-translational modifications of proteins,a process in which lactyl residues bind to the lysine residues of proteins.This modification can alter the structure,stability,and function of proteins,which in turn regulates cellular metabolism,aging,and the onset of disease.This review classifies proteins with lactylation effects into histones and non-histone proteins and analyzes their functional roles when lactylation occurs.The in-depth exploration of lactylation is still in its infancy,and many aspects of its regulation,functional significance and therapeutic potential need to be further explored.
基金Supported by the Natural Science Foundation of Anhui Provincial Department of Education(Grant Nos.KJ2020A 0993KJ2020ZD74)+2 种基金the High-Level Talent Research Start-Up Project(Grant No.DC2300000286)the Foundation of Guangzhou Civil Aviation College(Grant Nos.22X041824X4412).
文摘In the paper,a class of functions with bounded turnings involving cardioid domain,are studied in the region of the unit disc.The bounds of|a_(5)|,|a_(6)|,|a_(7)|and the fourth Hankel determinant are obtained,which are more accurate than those obtained by Srivastava.
文摘For the new subclass B of the bi-univalent functions constructed with the help of the(u,v)-Chebyshev polynomials of the second type,we get estimates for the first two initial coefficients and upper bounds of the Fekete-Szeg o functional.
基金Supported by The Innovation Fund of Postgraduate,Sichuan University of Science&Engineering(Y2024336)NSF of Sichuan Province(2023NSFSC0065).
文摘In this paper,we study asymptotic power series of the composition f(x)=h(g(x)),where g(x)=∑_(n=0)^(∞)b_(n)x^(-n),b_(n)∈R,and h is a given elementary function.The asymptotic expansions have been obtained for the composition with an exponential or logarithmic function.Using the re-cursive method,we present the asymptotic expansions for the composition with seven trigonometric functions,respectively.As an application,the asymptotic expansions of roots of some equations are given.Computational results show that our recursive formula is more efficient than the method of Lagrange's inverse theorem.
文摘The following article has been retracted due to the investigation of complaints received against it. The Editorial Board found that substantial portions of the text came from other published papers. The scientific community takes a very strong view on this matter, and the Health treats all unethical behavior such as plagiarism seriously. This paper published in Vol.3 No. 4, 334-339, 2012, has been removed from this site.
基金financially supported by the National Key R&D Program of China(No.2023YFA0915300)the National Natural Science Foundation of China(Nos.52233012,22405212 and22471219)the Funds for Creative Research Groups of China of the National Natural Science Foundation of China(No.21821001)。
文摘Intracellular polymerization is an emerging field,showcasing high diversity and efficiency of chemistry.Motivated by the principles of natural biomolecular synthesis,polymerization within living cells is believed to be a powerful and versatile tool to modulate cell behavior.In this review,we summarized recent advances and future trends in the field of intracellular polymerization,specifically focusing on covalent and supramolecular polymerization.This discussion comprehensively covers the diverse chemical designs,reaction mechanisms,responsive features,and functional applications.Furthermore,we also clarified the connection between preliminary design of polymer synthesis and their subsequent biological applications.We hope this review will serve as an innovative platform for chemists and biologists to regulate biological functions in practical applications and clinical trials.
基金supported by the National Natural Science Foundation of China(grant number:72304153)the Supporting Project of National Natural Science Foundation of China from Nanjing University of Chinese Medicine,China,(grant number:XPT72304153)the University Philosophy and Social Science Research in Jiangsu Province Jiangsu Province,China(grant number:2023SJYB0318)。
文摘Objectives:This prospective cohort study examined the change trajectories of cognitive and physical functions of individuals with motoric cognitive risk(MCR)syndrome,as well as the longitudinal associations between MCR syndrome and changes in cognitive and physical functions,to provide a new perspective on preventing dementia.Methods:Participants were selected from the China Health and Retirement Longitudinal Study(CHARLS).Demographic characteristics,health status,and lifestyle variables were assessed in 2011.MCR syndrome was defined as the presence of subjective cognitive complaints and objective slow gait,with preserved activities of daily living and absence of dementia,and assessed in 2011.Cognitive function,including orientation,attention and calculation,episodic memory,and visuospatial ability,was measured from 2011 to 2018.Physical function,including grip strength,balance ability,and repeated chair stand tests,was measured from 2011 to 2015.Generalized estimating equation was employed to analyze the longitudinal associations between MCR syndrome in 2011 and changes in cognitive functions over 7 years and physical functions over 4 years.Results:Among 4,217 participants,475 had MCR syndrome in 2011.Both participants with MCR syndrome and those without exhibited a decline in both cognitive and physical function over 7 years and 4 years of follow-up,except for fluctuations in visuospatial ability.Non-MCR syndrome participants demonstrated significantly better overall cognitive function in 2018 compared to 2011(Group×Time:B=0.44,P=0.035)than those in the MCR syndrome group.However,participants with non-MCR syndrome demonstrated significantly worse visuospatial ability in 2013(Group×time:B=−0.44,P=0.002)and 2018(Group×time:B=−0.34,P=0.016)compared to those in the MCR syndrome group.Non-MCR syndrome participants demonstrated significantly better performance in repeated chair stand tests in 2013(Group×time:B=0.31,P<0.001)and 2015(Group×time:B=0.37,P<0.001)compared to those in the MCR syndrome group in 2011.Conclusions:Older adults with MCR syndrome experience worse overall cognitive and physical function performance,especially in repeated chair stand tests,than individuals without MCR syndrome over 7-year and 4-year follow-up periods.It is suggested that future interventional studies will target both physical and cognitive functions in MCR syndrome individuals,providing insights for the prevention of dementia.
文摘In this paper,we study normal families of meromorphic functions.By using the idea in[16],we obtain some normality criteria for families of meromorphic functions concerning the wandering multiple functions,which extend and improve the well-known Montel's criterion,Bloch-Valiron's theorem,and the related results due to Carathéodory,and Grahl-Nevo et al..
基金funded by the University Teachers Innovation Fund Project of Gansu Province(2025A-001)the Northwest Normal University Young Teachers'Scientific Research Ability Improvement Plan(NWNULKQN2024-20).
文摘Accurately revealing the spatial heterogeneity in the trade-offs and synergies of land use functions(LUFs)and their driving factors is imperative for advancing sustainable land utilization and optimizing land use planning.This is especially critical for ecologically vulnerable inland river basins in arid regions.However,existing methods struggle to effectively capture complex nonlinear interactions among environmental factors and their multifaceted relationships with trade-offs and synergies of LUFs,especially for the inland river basins in arid regions.Consequently,this study focused on the middle reaches of the Heihe River Basin(MHRB),an arid inland river basin in northwestern China.Using land use,socioeconomic,meteorological,and hydrological data from 2000 to 2020,we analyzed the spatiotemporal patterns of LUFs and their trade-off and synergy relationships from the perspective of production,living,ecological functions.Additionally,we employed an integrated Extreme Gradient Boosting(XGBoost)-SHapley Additive exPlanations(SHAP)framework to investigate the environmental factors influencing the spatial heterogeneity in the trade-offs and synergies of LUFs.Our findings reveal that from 2000 to 2020,the production,living,and ecological functions of land use within the MHRB exhibited an increasing trend,demonstrating a distinct spatial pattern of''high in the southwest and low in the northeast''.Significant spatial heterogeneity defined the trade-off and synergistic relationships,with trade-offs dominating human activity-intensive oasis areas,while synergies prevailed in other areas.During the study period,synergistic relationships between production and living functions and between production and ecological functions were relatively robust,whereas synergies in living-ecological functions remained weaker.Natural factors(digital elevation model(DEM),annual mean temperature,Normalized Difference Vegetation Index(NDVI),and annual precipitation)emerged as the primary factors driving the trade-offs and synergies of LUFs,followed by socioeconomic factors(population density,Gross Domestic Product(GDP),and land use intensity),while distance factors(distance to water bodies,distance to residential areas,and distance to roads)exerted minimal influence.Notably,the interactions among NDVI,annual mean temperature,DEM,and land use intensity exerted the most substantial impacts on the relationships among LUFs.This study provides novel perspectives and methodologies for unraveling the mechanisms underlying the spatial heterogeneity in the trade-offs and synergies of LUFs,offering scientific insights to inform regional land use planning and sustainable natural resource management in inland river basins in arid regions.
基金Supported by the National Natural Science Foundation of China(Grant No.11471163)。
文摘In this paper,we obtain a normality criterion for families of meromorphic functions concerning‘wandering’shared functions,which generalizes and improves Montel’s criterion and the related results due to Schwick,Xu-Fang,Xu-Qiu,and Grahl-Nevo.Also,a normality relationship between two families is given.
基金Supported by Natural Science Research Project for Colleges and Universities of Anhui Province(Grant No.2022AH050329)Yunnan Provincial Department of Education Fund(Grant No.2025J0376).
文摘In this paper,we establish characterizations of α-Bloch functions and little α-Bloch functions on the unit ball as well as the unit polydisk of C^(m),which generalize and improve results of Aulaskari-Lappan,Minda,Aulaskari-Wulan,and Wu.Some examples are also given to complement our theory.
文摘The fourth-order B spline wavelet scaling functions are used to solve the two-dimensional unsteady diffusion equation. The calculations from a case history indicate that the method provides high accuracy and the computational efficiency is enhanced due to the small matrix derived from this method.The respective features of 3-spline wavelet scaling functions,4-spline wavelet scaling functions and quasi-wavelet used to solve the two-dimensional unsteady diffusion equation are compared. The proposed method has potential applications in many fields including marine science.
