Objective This study aimed to explore the clinical value of Children Neuropsychological and Behavioral Scale-Revision 2016(CNBS-R2016)for Autism Spectrum Disorder(ASD)screening in the presence of developmental surveil...Objective This study aimed to explore the clinical value of Children Neuropsychological and Behavioral Scale-Revision 2016(CNBS-R2016)for Autism Spectrum Disorder(ASD)screening in the presence of developmental surveillance.Methods All participants were evaluated by the CNBS-R2016 and Gesell Developmental Schedules(GDS).Spearman’s correlation coefficients and Kappa values were obtained.Taking GDS as a reference assessment,the performance of the CNBS-R2016 for detecting the developmental delays of children with ASD was analyzed with receiver operating characteristic(ROC)curves.The efficacy of the CNBS-R2016 to screen for ASD was explored by comparing Communication Warning Behavior with Autism Diagnostic Observation Schedule,Second Edition(ADOS-2).Results In total,150 children aged 12–42 months with ASD were enrolled.The developmental quotients of the CNBS-R2016 were correlated with those of the GDS(r=0.62–0.94).The CNBS-R2016 and GDS had good diagnostic agreement for developmental delays(Kappa=0.73–0.89),except for Fine Motor.There was a significant difference between the proportions of Fine Motor,delays detected by the CNBS-R2016 and GDS(86.0%vs.77.3%).With GDS as a standard,the areas under the ROC curves of the CNBS-R2016 were above 0.95 for all the domains except Fine Motor,which was 0.70.In addition,the positive rate of ASD was 100.0%and 93.5%when the cut-off points of 7 and 12 in the Communication Warning Behavior subscale were used,respectively.Conclusion The CNBS-R2016 performed well in developmental assessment and screening for children with ASD,especially by Communication Warning Behaviors subscale.Therefore,the CNBS-R2016 is worthy of clinical application in children with ASD in China.展开更多
The purpose of this study was to propose indicators for grasping autistic characteristics of people with intellectual disabilities who were going to engage in agricultural vocational training. We analyzed the data of ...The purpose of this study was to propose indicators for grasping autistic characteristics of people with intellectual disabilities who were going to engage in agricultural vocational training. We analyzed the data of the Childhood Autism Rating Scale (CARS) of 44 students at the high school course of a special needs education school who participated in agricultural vocational training. The data were divided into two groups according to the scores of “General Impressions”, one of 15 question items of the CARS: one was the group whose score was 1 (usual), and the other was the group whose scores were 1.5 to 4 (unusual). The results of the Mann-Whitney U test showed significant differences between two groups in eight items including “Relating to People” (p Relating to People” with six other items. As a result, “Relating to People” was considered to be the most effective item to know the participant’s autistic characteristics at a very early stage of training. Eventually, adding two items, “Body Use” and “Imitation” which are necessary to master agricultural tasks, to “Relating to People”, we proposed three indicators.展开更多
基金This study was supported by Emergency Technology Research Project of Huazhong University of Science and Technology(No.2020kfyXGYJ020).
文摘Objective This study aimed to explore the clinical value of Children Neuropsychological and Behavioral Scale-Revision 2016(CNBS-R2016)for Autism Spectrum Disorder(ASD)screening in the presence of developmental surveillance.Methods All participants were evaluated by the CNBS-R2016 and Gesell Developmental Schedules(GDS).Spearman’s correlation coefficients and Kappa values were obtained.Taking GDS as a reference assessment,the performance of the CNBS-R2016 for detecting the developmental delays of children with ASD was analyzed with receiver operating characteristic(ROC)curves.The efficacy of the CNBS-R2016 to screen for ASD was explored by comparing Communication Warning Behavior with Autism Diagnostic Observation Schedule,Second Edition(ADOS-2).Results In total,150 children aged 12–42 months with ASD were enrolled.The developmental quotients of the CNBS-R2016 were correlated with those of the GDS(r=0.62–0.94).The CNBS-R2016 and GDS had good diagnostic agreement for developmental delays(Kappa=0.73–0.89),except for Fine Motor.There was a significant difference between the proportions of Fine Motor,delays detected by the CNBS-R2016 and GDS(86.0%vs.77.3%).With GDS as a standard,the areas under the ROC curves of the CNBS-R2016 were above 0.95 for all the domains except Fine Motor,which was 0.70.In addition,the positive rate of ASD was 100.0%and 93.5%when the cut-off points of 7 and 12 in the Communication Warning Behavior subscale were used,respectively.Conclusion The CNBS-R2016 performed well in developmental assessment and screening for children with ASD,especially by Communication Warning Behaviors subscale.Therefore,the CNBS-R2016 is worthy of clinical application in children with ASD in China.
文摘The purpose of this study was to propose indicators for grasping autistic characteristics of people with intellectual disabilities who were going to engage in agricultural vocational training. We analyzed the data of the Childhood Autism Rating Scale (CARS) of 44 students at the high school course of a special needs education school who participated in agricultural vocational training. The data were divided into two groups according to the scores of “General Impressions”, one of 15 question items of the CARS: one was the group whose score was 1 (usual), and the other was the group whose scores were 1.5 to 4 (unusual). The results of the Mann-Whitney U test showed significant differences between two groups in eight items including “Relating to People” (p Relating to People” with six other items. As a result, “Relating to People” was considered to be the most effective item to know the participant’s autistic characteristics at a very early stage of training. Eventually, adding two items, “Body Use” and “Imitation” which are necessary to master agricultural tasks, to “Relating to People”, we proposed three indicators.