The main aim of this paper is a classification of non-trivial 2-(v,5,λ)designs admitting a block-transitive automorphism group.Let D=(P,B)be a non-trivial 2-(v,5,λ)design and G be a block-transitive automorphism gro...The main aim of this paper is a classification of non-trivial 2-(v,5,λ)designs admitting a block-transitive automorphism group.Let D=(P,B)be a non-trivial 2-(v,5,λ)design and G be a block-transitive automorphism group of D.In this paper,we prove that if Soc(G)is an alternating simple group,then the rank of G is at most 3.Moreover,we determine all pairs(D,G).展开更多
The preparation and functionalization of polymeric capsules attract intense attention due to their application in various areas.Herein we presented an amphiphilic alternating copolymer(ACP)-based microcapsule which is...The preparation and functionalization of polymeric capsules attract intense attention due to their application in various areas.Herein we presented an amphiphilic alternating copolymer(ACP)-based microcapsule which is both robust and readily-functionalized through interfacial click polymerization.A water-in-oil emulsion was constructed to act as the reaction medium,the hydrophilic 1,3-butadiene diepoxide(BDE)in water phase reacted with the oleophilic 1,4-dibutanedithiol(BDT)in oil phase at the water-oil interface to form the amphiphilic ACP named poly(2,3-dihydroxy butylene-alt-butylene dithioether)(abbreviated as P(DHB-a-BDT)below),which would deposite in situ to form the micro-sized capsules.Significantly,the dried capsules are robust enough to be rehydrated once the water was added and almost restored their original morphologies.Further elucidation showed that the Young's modulus of these capsules exceeded 1 GPa.As long as we know,it is the first time for the mechanical properties of the ACP-based microstructures being investigated.Besides,functionalization could be achieved simultaneously with the formation process.As a proof of concept,positive-charged capsules were successfully obtained through click copolymerization.Stemming from the unique characteristics of amphiphilic ACPs which combined both merits of click chemistry and interfacial reactions,all these features of the current method as well as the resultant capsules may promote the application of the polymeric capsules.展开更多
Deep learning methods have achieved significant progress in solving partial differential equations.However,when applied to the widely used anisotropic scattering neutron transport equations in reactor engineering,thes...Deep learning methods have achieved significant progress in solving partial differential equations.However,when applied to the widely used anisotropic scattering neutron transport equations in reactor engineering,these encounter significant challenges.To address this issue,this study introduces a multi-antiderivative transformation alternating iterative deep learning method(M-AIM).This method transforms the integral terms of the scattering and fission sources in the transport equation into multiple antiderivative functions corresponding to the integrand,converts the differential-integral form of the transport equation into an exact differential equation,and establishes the necessary constraints for a unique solution.The M-AIM uses multiple deep neural networks to map the unknown angular flux density of transport equations and represents various forms of antiderivative functions.It constructs the corresponding weighted loss functions.By alternating iterative training with deep learning methods applied to these neural networks,the loss is reduced gradually.When the loss decreases to a preset minimum,the neural network approaches a numerical solution for both angular flux density and antiderivative functions.This paper presents a numerical verification of geometries such as flat plates and spheres.It verifies the validity of the theoretical framework and associated methods.The study contributes to the development of novel technical approaches for applying deep learning to solve anisotropic scattering neutron transport equations in reactor engineering.展开更多
The ring-opening alternating copolymerization(ROAC)of 3,4-dihydrocoumarin(DHC)/epoxides has been successfully developed using an imidazolium salt of 1-ethyl-3-methylimidazolium chloride(EMIMCl)as a catalyst.The result...The ring-opening alternating copolymerization(ROAC)of 3,4-dihydrocoumarin(DHC)/epoxides has been successfully developed using an imidazolium salt of 1-ethyl-3-methylimidazolium chloride(EMIMCl)as a catalyst.The resulting copolymer has a molecular weight of 13.7kg·mol^(-1),a narrow molecular weight distribution of 1.03 and a strictly alternating structure.The MALDI-TOF MS characterization and DFT calculations including electrostatic potential(ESP),hydrogen-atom abstraction(HAA),independent gradient model based on hirshfeld partition(IGMH)and atoms-in-molecules(AIM)analysis were used to investigate the metal-free catalytic process.The synergistic effect of anions and cations of EMIMCl for ROAC of DHC and epoxides was demonstrated.This study provides a metal-free catalytic system for the facile synthesis of alternating polyesters from DHC.展开更多
Prefabricated twinning represents an effective strategy for optimizing the microstructure of extruded forming components and facilitating changes in texture.The study examines the incorporation of[10-12]twins into an ...Prefabricated twinning represents an effective strategy for optimizing the microstructure of extruded forming components and facilitating changes in texture.The study examines the incorporation of[10-12]twins into an AZ31 magnesium alloy billet via cold pre-upsetting deformation before alternating forward extrusion(CUAFE).The experimental results indicate that the initial presence of[10-12]twins is advantageous for the development of[10-10]and[11-20]texture components during the extrusion process.In addition,different DRX mechanisms have different influences on the evolution of basal texture.The CDRX grains tend to preferentially select the[11-20]texture orientation,weakening the[10-10]texture and enhancing the[11-20]texture.However,most DDRX grains deviate significantly from the orientation of their surrounding original grain and do not have a preferred orientation.This is reflected in the mechanical properties of the CUAFE part.The tensile strength is 323.5 MPa,while the elongation is as high as 20.1%.展开更多
The results of the study of the effect of partial substitution of Fe by Mn in the La Fe_(11.2-x)Mn_(x)Co_(0.7)Si_(1.1)system on magnetization,specific heat,magnetostriction and magnetocaloric effect are presented.Dire...The results of the study of the effect of partial substitution of Fe by Mn in the La Fe_(11.2-x)Mn_(x)Co_(0.7)Si_(1.1)system on magnetization,specific heat,magnetostriction and magnetocaloric effect are presented.Direct measurements of the adiabatic temperature change(ΔT_(ad))were carried out in alternating magnetic fields(AMF)using the magnetic field modulation method.Partial substitution of Fe atoms by Mn atoms leads to a shift in the Curie temperature(T_(C))towards lower temperatures without a noticeable deterioration in magnetic properties.A correlation was found between the structural component of the magnetocaloric effect and the stability of the frequency of theΔT_(ad)in the AMFs—an increase in the manganese concentration leads to a decrease in magnetostriction and to a lower dependence ofΔT_(ad)on the frequency of the magnetic field.Estimates of the specific cooling power Q_(C)as a function of the frequency of the AMF showed that the highest value of Q_(C)at f=20 Hz in a magnetic field of 12k Oe is 26.3 W g^(-1)and is observed for the composition with x=0.1.This value is higher than that of Gd,for which,under the same conditions,Q_(C)=21.6 W g^(-1).All the samples studied show stability of the value ofΔT_(ad)without any sign of deterioration of the effect up to 60,000cycles of switching on/off of the magnetic field of 12 k Oe.The discovered frequency and cyclic stability ofΔT_(ad)of the studied samples increase their prospects for application in magnetic cooling technology.展开更多
With the continuous advancement of electronic devices,flexible thin films with both thermal manage-ment functions and excellent electromagnetic interference(EMI)shielding properties have received much attention.Hence,...With the continuous advancement of electronic devices,flexible thin films with both thermal manage-ment functions and excellent electromagnetic interference(EMI)shielding properties have received much attention.Hence,inspired by Janus,a CNF/MXene/ZnFe2O4@PANI composite film with an asymmetric gradient alternating structure was successfully prepared by adjusting the filler content of the conduc-tive and magnetic layers using a vacuum-assisted filtration method.Benefiting from the magnetic reso-nance and hysteresis loss of ZnFe2O4@PANI,conductive loss and dipole polarization of MXene,as well as the exclusive"absorption-reflection-reabsorption"shielding feature in the alternating multilayered films,CM&CZFP-4 G film has superior EMI shielding performance,with an EMI SE of up to 45.75 dB and shield-ing effectiveness of 99.99%.Surprisingly,the composite film maintains reliable EMI shielding properties even after prolonged erosion in harsh environments such as high/low temperatures,high humidity,acids and alkalis.Furthermore,the CM&CZFP-4 G responded quickly within about 50 s and reached a maximum steady-state temperature of 235.8℃ at an applied voltage of 9.0 V,indicating the obtained film acquired outstanding and controllable Joule heating performance.This result was attributed to the homogeneous dispersion of MXene to build up a conductive network and endow the CNF/MXene with high conduc-tivity.Meanwhile,the fire resistance of CM&CZFP-4 G was significantly improved compared to pure CNF,which guaranteed fire safety during its application.Additionally,contributed by long fiber entanglement of CNF,extensive hydrogen-bonding interactions and multilayer structural design,the CM&CZFP-4 G film exhibits excellent mechanical characteristics,with the tensile strength and fracture strain of 27.74 MPa and 6.21%,separately.This work offers a creative avenue to prepare multifunctional composite films with electromagnetic shielding and Joule heating for various application environments.展开更多
The application of multi-material topology optimization affords greater design flexibility compared to traditional single-material methods.However,density-based topology optimization methods encounter three unique cha...The application of multi-material topology optimization affords greater design flexibility compared to traditional single-material methods.However,density-based topology optimization methods encounter three unique challenges when inertial loads become dominant:non-monotonous behavior of the objective function,possible unconstrained characterization of the optimal solution,and parasitic effects.Herein,an improved Guide-Weight approach is introduced,which effectively addresses the structural topology optimization problem when subjected to inertial loads.Smooth and fast convergence of the compliance is achieved by the approach,while also maintaining the effectiveness of the volume constraints.The rational approximation of material properties model and smooth design are utilized to guarantee clear boundaries of the final structure,facilitating its seamless integration into manufacturing processes.The framework provided by the alternating active-phase algorithm is employed to decompose the multi-material topological problem under inertial loading into a set of sub-problems.The optimization of multi-material under inertial loads is accomplished through the effective resolution of these sub-problems using the improved Guide-Weight method.The effectiveness of the proposed approach is demonstrated through numerical examples involving two-phase and multi-phase materials.展开更多
BACKGROUND Working memory serves as a fundamental cognitive function that substantially impacts performance in various cognitive tasks.Extensive neurophysiological research has established that theta oscillations(4-8 ...BACKGROUND Working memory serves as a fundamental cognitive function that substantially impacts performance in various cognitive tasks.Extensive neurophysiological research has established that theta oscillations(4-8 Hz)play an essential role in supporting working memory operations.Theta-band transcranial alternating current stimulation(tACS)offers a potential mechanism for working memory enhancement through direct modulation of these fundamental neural oscillations.Nevertheless,current empirical evidence shows substantial variability in the observed effects of theta-tACS across studies.AIM To conduct a systematic review and meta-analysis evaluating the effects of thetatACS on working memory performance in healthy adults.METHODS A systematic literature search was performed on PubMed,EMBASE,and Web of Science up to March 10,2025.Effect sizes were computed using Hedges’g with 95%confidence intervals(CIs),with separate meta-analyses for all included studies and for distinct working memory paradigms[n-back and delayed matchto-sample(DMTS)tasks]to examine potential task-specific effects.Subgroup analyses and meta-regression were performed to evaluate the influence of key moderating variables.RESULTS The systematic review included 21 studies(67 effect sizes).Initial meta-analysis showed theta-tACS moderately improved working memory(Hedges’g=0.405,95%CI:0.212-0.598).However,this effect became nonsignificant after correcting for publication bias(trim-and-fill adjusted Hedges’g=0.082,95%CI:-0.052 to 0.217).Task-specific analyses revealed significant benefits in n-back tasks(Hedges’g=0.463,95%CI:0.193-0.733)but not in DMTS tasks(Hedges’g=0.257,95%CI:-0.186 to 0.553).Moderator analyses showed that performance in n-back tasks was influenced by stimulation frequency(P=0.001),concurrent status(P=0.014),task modality(P=0.005),and duration(P=0.013),whereas only the region of targeted stimulation(P=0.012)moderated DMTS tasks.CONCLUSION Theta-tACS enhances working memory in healthy adults,with effects modulated by the task type and protocol parameters,offering dual implications for cognitive enhancement and clinical interventions.展开更多
An alternating magnetic field(AMF)was introduced into the narrow gap laser-arc hybrid welding process for 2205 duplex stainless steel thick plates.The corrosion performance of the welded joints was evaluated through e...An alternating magnetic field(AMF)was introduced into the narrow gap laser-arc hybrid welding process for 2205 duplex stainless steel thick plates.The corrosion performance of the welded joints was evaluated through electrochemical studies.The results revealed that joints welded with the application of AMF had a lower corrosion current density compared to those welded without an external AMF.Additionally,these joints showed higher pitting potential and polarization resistance.Microscopic electrochemical analysis indicated that joints subjected to AMF exhibited minimal cathodic current in simulated seawater,with only slight fluctuations in the anodic current peak.Overall,the corrosion levels on the joint surfaces were relatively low.After 4 h of immersion in the corrosive medium,the average impedance of joints exposed to AMF increased by 60.7%compared to those not influenced by a magnetic field.These findings suggest that applying AMF during the narrow gap laser-arc hybrid welding process can significantly improve the corrosion resistance of duplex stainless steel welded joints,reducing their susceptibility to stress corrosion in seawater-like environments.展开更多
The Global Position System(GPS)is a reliable method for positioning in most scenarios,but it falls short in harsh environments like urban vehicular scenarios,where numerous trees or flyovers obstruct the signals.This ...The Global Position System(GPS)is a reliable method for positioning in most scenarios,but it falls short in harsh environments like urban vehicular scenarios,where numerous trees or flyovers obstruct the signals.This presents an unprecedented challenge for autonomous vehicles or applications requiring high accuracy.Fortunately,vehicular ad-hoc networks(VANET)offer an effective solution,where vehicle-to-vehicle(V2V)and vehicle-to-infrastructure(V2I)communications are used to enhance location awareness.In V2I communications,the roadside units(RSU)transmit beacon packets,and the vehicle receives numerous packets from different RSUs to establish communication.To further improve localization accuracy,a cross-covariance matrices-alternating least square(CCM-ALS)algorithm is proposed.The algorithm relies on ALS of the CCM for obtaining the position of vehicles in V2I communications.The algorithm is highly precise compared to traditional angle of arrival(AOA)positioning and not inferior to direct position determination(DPD)approaches while being low in complexity,which is crucial for moving vehicles.The numerical results verify the superiority of the proposed method.展开更多
The quantum alternating operator ansatz algorithm(QAOA+)is widely used for constrained combinatorial optimization problems(CCOPs)due to its ability to construct feasible solution spaces.In this paper,we propose a prog...The quantum alternating operator ansatz algorithm(QAOA+)is widely used for constrained combinatorial optimization problems(CCOPs)due to its ability to construct feasible solution spaces.In this paper,we propose a progressive quantum algorithm(PQA)to reduce qubit requirements for QAOA+in solving the maximum independent set(MIS)problem.PQA iteratively constructs a subgraph likely to include the MIS solution of the original graph and solves the problem on it to approximate the global solution.Specifically,PQA starts with a small-scale subgraph and progressively expands its graph size utilizing heuristic expansion strategies.After each expansion,PQA solves the MIS problem on the newly generated subgraph using QAOA+.In each run,PQA repeats the expansion and solving process until a predefined stopping condition is reached.Simulation results show that PQA achieves an approximation ratio of 0.95 using only 5.57%(2.17%)of the qubits and 17.59%(6.43%)of the runtime compared with directly solving the original problem with QAOA+on Erd?s-Rényi(3-regular)graphs,highlighting the efficiency and scalability of PQA.展开更多
Glioblastoma(GBM)is an aggressive brain tumor with limited treatment options and a dismal prognosis.While immunotherapy has shown promise in treating some solid tumors,the treatment of GBM has been mostly unsuccessful...Glioblastoma(GBM)is an aggressive brain tumor with limited treatment options and a dismal prognosis.While immunotherapy has shown promise in treating some solid tumors,the treatment of GBM has been mostly unsuccessful because of a lack of targetable tumor antigens and high tumor heterogeneity.Here,we report RCAN1-4 as a novel tumor antigen derived from alternative splicing induced by the transcription factor C/EBPβ.Both C/EBPβand RCAN1-4 are highly expressed in GBM and glioma stem cells as mesenchymal subtype hallmarks.We report an immunogenic HLA-A24-specific splicing junction epitope within exon 4 and exon 5 that is unique to RCAN1-4.This epitope was validated for its ability to stimulate T cell responses in HLA-A24^(+)donors and GBM patients,leading us to identify RCAN1-4-reactive T cell receptors(TCRs)for the construction of TCR-engineered T cells(TCR-T cells).Functional studies of TCR-Ts demonstrated the in vitro and in vivo killing of RCAN1-4pos GBM tumor cells,highlighting its potential as an immunotherapeutic target in mesenchymal GBM.展开更多
The ectomycorrhizal fungus Paxillus involutus was inoculated onto tissue-cultures of the hybrid poplar,Populus davidiana×P.bolleana,to evaluate the elemental defense effect to heavy metals copper and cadmium at d...The ectomycorrhizal fungus Paxillus involutus was inoculated onto tissue-cultures of the hybrid poplar,Populus davidiana×P.bolleana,to evaluate the elemental defense effect to heavy metals copper and cadmium at different concentrations by simulating Alternaria alternata fungus infection.The enrichment capacity of Populus davidiana×P.bolleana for Cu and Cd was closely associated with the degree of heavy metal stress.There was a significant positive interaction of applying Cu and Cd and the inoculation with P.involutus on A.alternata leaf blight disease index.The incidence rate and disease index of leaf blight underwent a significant reduction compared with the controls.Similarly,the ratio of the area of disease spot to leaf area,incidence rate,and disease index for Populus davidiana×P.bolleana leaves inoculated with Paxillus involutus(Batsch)Fr.were significantly lower than those of their nonmycorrhizal counterparts.With increasing the degree of Cu and Cd stress,a gradual increase in the average value of the membership function for the incidence rate and disease index was observed,indicating the weakened pathogen's ability to cause infection and the improved resistance of Populus davidiana×P.bolleana to leaf blight disease under Cu and Cd stress.Moreover,superoxide dismutase enzyme activity in Populus davidiana×P.bolleana increased significantly,reaching levels of 411.0 U/g FW and 421.6 U/g FW under Cu and Cd treatments,respectively.These changes in metabolic products and antioxidant enzyme activities suggest that P.involutus may enhance the resistance of Populus davidiana×P.bolleana to the fungus,Alternaria alternata Fr.Keissel under heavy metal stress by modulating these physiological indicators.展开更多
Alternate wetting and drying irrigation(AWD)significantly influences the cooking and eating quality of rice(Oryza sativa L.).However,the mechanisms by which AWD affects rice cooking and eating quality remain unclear.L...Alternate wetting and drying irrigation(AWD)significantly influences the cooking and eating quality of rice(Oryza sativa L.).However,the mechanisms by which AWD affects rice cooking and eating quality remain unclear.Lipid and free fatty acid contents in grains correlate positively with cooking and eating quality of rice.This study examined Yangdao 6(YD6,a conventional taste indica inbred)and Nanjing 9108(NJ9108,a superior taste japonica inbred)cultivated under conventional irrigation(CI),alternate wetting and moderate drying irrigation(AWMD),and alternate wetting and severe drying irrigation(AWSD)from 10 days after transplanting to maturity.The research investigated the relationship between lipid and free fatty acid biosynthesis in grains and the cooking and eating quality of rice.Compared to CI treatment,AWMD significantly enhanced the contents of lipid,total free fatty acids(TFFAs),free unsaturated fatty acids(FUFAs),linoleic acid,and oleic acid in milled rice by increasing activities of enzymes associated with lipid synthesis,while AWSD produced opposite effects.Correlation analysis revealed that elevated levels of lipid,TFFAs,FUFAs,linoleic acid,and oleic acid contribute to improved rice cooking and eating quality.The findings demonstrate that AWMD enhances cooking and eating quality of milled rice through optimization of lipid and fatty acid synthesis in rice grains.展开更多
A novel algorithm, i.e. the fast alternating direction method of multipliers （ADMM）, is applied to solve the classical total-variation （ TV ）-based model for image reconstruction. First, the TV-based model is refo...A novel algorithm, i.e. the fast alternating direction method of multipliers （ADMM）, is applied to solve the classical total-variation （ TV ）-based model for image reconstruction. First, the TV-based model is reformulated as a linear equality constrained problem where the objective function is separable. Then, by introducing the augmented Lagrangian function, the two variables are alternatively minimized by the Gauss-Seidel idea. Finally, the dual variable is updated. Because the approach makes full use of the special structure of the problem and decomposes the original problem into several low-dimensional sub-problems, the per iteration computational complexity of the approach is dominated by two fast Fourier transforms. Elementary experimental results indicate that the proposed approach is more stable and efficient compared with some state-of-the-art algorithms.展开更多
The effects of alternating magnetic field on the corrosion morphologies, corrosion rate, and corrosion products of copper in 3.5% NaCl solution, sea water, and magnetized sea water were investigated using electrochemi...The effects of alternating magnetic field on the corrosion morphologies, corrosion rate, and corrosion products of copper in 3.5% NaCl solution, sea water, and magnetized sea water were investigated using electrochemical test, scanning electron microscopy/energy dispersive analysis system of X-ray （SEM/EDAX）, and X-ray diffraction （XRD）. The results show that the corrosion rate of copper in magnetized sea water is minimal. Moreover, the surface of the specimen in magnetized sea water is uniform and compact as compared with those in 3.5% NaCl solution and sea water. The corrosion products of copper in magnetized sea water are mainly Cu2O and CuCl2. However, the corrosion products in sea water are CuCl, Cu2Cl（OH）3, and FeCl3-6H2O. The electrochemical corrosion mechanisms of copper in the three media were also discussed.展开更多
Linear scan computed tomography （LCT） is of great benefit to online industrial scanning and security inspection due to its characteristics of straight-line source trajectory and high scanning speed. However, in prac...Linear scan computed tomography （LCT） is of great benefit to online industrial scanning and security inspection due to its characteristics of straight-line source trajectory and high scanning speed. However, in practical applications of LCT, there are challenges to image reconstruction due to limited-angle and insufficient data. In this paper, a new reconstruction algorithm based on total-variation （TV） minimization is developed to reconstruct images from limited-angle and insufficient data in LCT. The main idea of our approach is to reformulate a TV problem as a linear equality constrained problem where the objective function is separable, and then minimize its augmented Lagrangian function by using alternating direction method （ADM） to solve subproblems. The proposed method is robust and efficient in the task of reconstruction by showing the convergence of ADM. The numerical simulations and real data reconstructions show that the proposed reconstruction method brings reasonable performance and outperforms some previous ones when applied to an LCT imaging problem.展开更多
With rapid economic development in China, demand for energy and transportation is growing. Due to the limitations of factors such as terrain and traffic, a large number of buried oil and gas pipelines are parallel to ...With rapid economic development in China, demand for energy and transportation is growing. Due to the limitations of factors such as terrain and traffic, a large number of buried oil and gas pipelines are parallel to high- voltage transmission lines and electrified railways over long distances. Alternating pipelines is very serious in laboratory experiments were current （AC） corrosion of such cases. In this work, carried out with an electrochemical method in a simulated soil solution at various AC current densities from 0 to 200 A]m2 and AC frequencies from 10 to 200 Hz. Experimental results indicated that with an increase in the AC current density, the corrosion po- tential of an X60 steel electrode shifted negatively, the anodic current density increased significantly, and the corrosion rate increased. Moreover, with an increase in the AC frequency, the corrosion potential of the X60 electrode shifted positively and the anodic current density decreased, which led to a decrease in the corrosion rate. Furthermore, the morphology of X60 electrodes indicated that uniform corrosion occurred at a low AC current density; while corrosion pits were found on the X60 electrode surface at a high AC current density, and deep corrosion pits seriously damaged the pipelines and might lead to leakage.展开更多
基金Supported by the National Natural Science Foundation of China(Grant No.12361004)the Natural Science Foun-dation of Jiangxi Province(Grant Nos.20224BAB211005,20242BAB25005)the Natural Science Foundation of Henan Province(Grant No.242300421688).
文摘The main aim of this paper is a classification of non-trivial 2-(v,5,λ)designs admitting a block-transitive automorphism group.Let D=(P,B)be a non-trivial 2-(v,5,λ)design and G be a block-transitive automorphism group of D.In this paper,we prove that if Soc(G)is an alternating simple group,then the rank of G is at most 3.Moreover,we determine all pairs(D,G).
基金financially supported by the Fundamental Research Funds for Central Universities(No.24D110627)。
文摘The preparation and functionalization of polymeric capsules attract intense attention due to their application in various areas.Herein we presented an amphiphilic alternating copolymer(ACP)-based microcapsule which is both robust and readily-functionalized through interfacial click polymerization.A water-in-oil emulsion was constructed to act as the reaction medium,the hydrophilic 1,3-butadiene diepoxide(BDE)in water phase reacted with the oleophilic 1,4-dibutanedithiol(BDT)in oil phase at the water-oil interface to form the amphiphilic ACP named poly(2,3-dihydroxy butylene-alt-butylene dithioether)(abbreviated as P(DHB-a-BDT)below),which would deposite in situ to form the micro-sized capsules.Significantly,the dried capsules are robust enough to be rehydrated once the water was added and almost restored their original morphologies.Further elucidation showed that the Young's modulus of these capsules exceeded 1 GPa.As long as we know,it is the first time for the mechanical properties of the ACP-based microstructures being investigated.Besides,functionalization could be achieved simultaneously with the formation process.As a proof of concept,positive-charged capsules were successfully obtained through click copolymerization.Stemming from the unique characteristics of amphiphilic ACPs which combined both merits of click chemistry and interfacial reactions,all these features of the current method as well as the resultant capsules may promote the application of the polymeric capsules.
基金supported by the National Natural Science Foundation of China(No.12575189)。
文摘Deep learning methods have achieved significant progress in solving partial differential equations.However,when applied to the widely used anisotropic scattering neutron transport equations in reactor engineering,these encounter significant challenges.To address this issue,this study introduces a multi-antiderivative transformation alternating iterative deep learning method(M-AIM).This method transforms the integral terms of the scattering and fission sources in the transport equation into multiple antiderivative functions corresponding to the integrand,converts the differential-integral form of the transport equation into an exact differential equation,and establishes the necessary constraints for a unique solution.The M-AIM uses multiple deep neural networks to map the unknown angular flux density of transport equations and represents various forms of antiderivative functions.It constructs the corresponding weighted loss functions.By alternating iterative training with deep learning methods applied to these neural networks,the loss is reduced gradually.When the loss decreases to a preset minimum,the neural network approaches a numerical solution for both angular flux density and antiderivative functions.This paper presents a numerical verification of geometries such as flat plates and spheres.It verifies the validity of the theoretical framework and associated methods.The study contributes to the development of novel technical approaches for applying deep learning to solve anisotropic scattering neutron transport equations in reactor engineering.
基金financially supported by the National Natural Science Foundation of China(No.22161040)Natural Science Foundation of Gansu(No.24JRRA125)Science Research Project of Northwest Normal University(No.NWNU-LKZD2021-3)。
文摘The ring-opening alternating copolymerization(ROAC)of 3,4-dihydrocoumarin(DHC)/epoxides has been successfully developed using an imidazolium salt of 1-ethyl-3-methylimidazolium chloride(EMIMCl)as a catalyst.The resulting copolymer has a molecular weight of 13.7kg·mol^(-1),a narrow molecular weight distribution of 1.03 and a strictly alternating structure.The MALDI-TOF MS characterization and DFT calculations including electrostatic potential(ESP),hydrogen-atom abstraction(HAA),independent gradient model based on hirshfeld partition(IGMH)and atoms-in-molecules(AIM)analysis were used to investigate the metal-free catalytic process.The synergistic effect of anions and cations of EMIMCl for ROAC of DHC and epoxides was demonstrated.This study provides a metal-free catalytic system for the facile synthesis of alternating polyesters from DHC.
基金supported by the National Natural Science Foundation of China(No.52475341).
文摘Prefabricated twinning represents an effective strategy for optimizing the microstructure of extruded forming components and facilitating changes in texture.The study examines the incorporation of[10-12]twins into an AZ31 magnesium alloy billet via cold pre-upsetting deformation before alternating forward extrusion(CUAFE).The experimental results indicate that the initial presence of[10-12]twins is advantageous for the development of[10-10]and[11-20]texture components during the extrusion process.In addition,different DRX mechanisms have different influences on the evolution of basal texture.The CDRX grains tend to preferentially select the[11-20]texture orientation,weakening the[10-10]texture and enhancing the[11-20]texture.However,most DDRX grains deviate significantly from the orientation of their surrounding original grain and do not have a preferred orientation.This is reflected in the mechanical properties of the CUAFE part.The tensile strength is 323.5 MPa,while the elongation is as high as 20.1%.
基金financially supported by Russian Science Foundation(No.24-43-00156,https://rscf.ru/en/project/24-43-00156/)the National Natural Science Foundation of China(No.52171169)the State Key Laboratory for Advanced Metals and Materials(No.2023-ZD01)。
文摘The results of the study of the effect of partial substitution of Fe by Mn in the La Fe_(11.2-x)Mn_(x)Co_(0.7)Si_(1.1)system on magnetization,specific heat,magnetostriction and magnetocaloric effect are presented.Direct measurements of the adiabatic temperature change(ΔT_(ad))were carried out in alternating magnetic fields(AMF)using the magnetic field modulation method.Partial substitution of Fe atoms by Mn atoms leads to a shift in the Curie temperature(T_(C))towards lower temperatures without a noticeable deterioration in magnetic properties.A correlation was found between the structural component of the magnetocaloric effect and the stability of the frequency of theΔT_(ad)in the AMFs—an increase in the manganese concentration leads to a decrease in magnetostriction and to a lower dependence ofΔT_(ad)on the frequency of the magnetic field.Estimates of the specific cooling power Q_(C)as a function of the frequency of the AMF showed that the highest value of Q_(C)at f=20 Hz in a magnetic field of 12k Oe is 26.3 W g^(-1)and is observed for the composition with x=0.1.This value is higher than that of Gd,for which,under the same conditions,Q_(C)=21.6 W g^(-1).All the samples studied show stability of the value ofΔT_(ad)without any sign of deterioration of the effect up to 60,000cycles of switching on/off of the magnetic field of 12 k Oe.The discovered frequency and cyclic stability ofΔT_(ad)of the studied samples increase their prospects for application in magnetic cooling technology.
基金supported by the National Natural Science Foundation of China(Nos.22005277,52474256 and 52074247)the Natural Science Foundation of Hubei Province(No.2024AFB662)+1 种基金the Young Top-notch Talent Cultivation Program of Hubei Province,Opening Foundation of State Key Laboratory of Organic-Inorganic Composites,Beijing University of Chemical Technology(No.oic-202401012)the Fundamental Research Funds for National Universities,China University of Geosciences(No.2024XLA93).
文摘With the continuous advancement of electronic devices,flexible thin films with both thermal manage-ment functions and excellent electromagnetic interference(EMI)shielding properties have received much attention.Hence,inspired by Janus,a CNF/MXene/ZnFe2O4@PANI composite film with an asymmetric gradient alternating structure was successfully prepared by adjusting the filler content of the conduc-tive and magnetic layers using a vacuum-assisted filtration method.Benefiting from the magnetic reso-nance and hysteresis loss of ZnFe2O4@PANI,conductive loss and dipole polarization of MXene,as well as the exclusive"absorption-reflection-reabsorption"shielding feature in the alternating multilayered films,CM&CZFP-4 G film has superior EMI shielding performance,with an EMI SE of up to 45.75 dB and shield-ing effectiveness of 99.99%.Surprisingly,the composite film maintains reliable EMI shielding properties even after prolonged erosion in harsh environments such as high/low temperatures,high humidity,acids and alkalis.Furthermore,the CM&CZFP-4 G responded quickly within about 50 s and reached a maximum steady-state temperature of 235.8℃ at an applied voltage of 9.0 V,indicating the obtained film acquired outstanding and controllable Joule heating performance.This result was attributed to the homogeneous dispersion of MXene to build up a conductive network and endow the CNF/MXene with high conduc-tivity.Meanwhile,the fire resistance of CM&CZFP-4 G was significantly improved compared to pure CNF,which guaranteed fire safety during its application.Additionally,contributed by long fiber entanglement of CNF,extensive hydrogen-bonding interactions and multilayer structural design,the CM&CZFP-4 G film exhibits excellent mechanical characteristics,with the tensile strength and fracture strain of 27.74 MPa and 6.21%,separately.This work offers a creative avenue to prepare multifunctional composite films with electromagnetic shielding and Joule heating for various application environments.
基金supported by the National Natural Science Foundation of China(Grant No.52172356)the Hunan Provincial Natural Science Foundation of China(Grant No.2022JJ10012).
文摘The application of multi-material topology optimization affords greater design flexibility compared to traditional single-material methods.However,density-based topology optimization methods encounter three unique challenges when inertial loads become dominant:non-monotonous behavior of the objective function,possible unconstrained characterization of the optimal solution,and parasitic effects.Herein,an improved Guide-Weight approach is introduced,which effectively addresses the structural topology optimization problem when subjected to inertial loads.Smooth and fast convergence of the compliance is achieved by the approach,while also maintaining the effectiveness of the volume constraints.The rational approximation of material properties model and smooth design are utilized to guarantee clear boundaries of the final structure,facilitating its seamless integration into manufacturing processes.The framework provided by the alternating active-phase algorithm is employed to decompose the multi-material topological problem under inertial loading into a set of sub-problems.The optimization of multi-material under inertial loads is accomplished through the effective resolution of these sub-problems using the improved Guide-Weight method.The effectiveness of the proposed approach is demonstrated through numerical examples involving two-phase and multi-phase materials.
基金Supported by Shanghai Municipal Health Commission’s Special Clinical Research Project for the Hygiene Industry,No.20244Y0041Youth Initiation Fund of Naval Medical University,No.2023QN028 and No.2023QN030。
文摘BACKGROUND Working memory serves as a fundamental cognitive function that substantially impacts performance in various cognitive tasks.Extensive neurophysiological research has established that theta oscillations(4-8 Hz)play an essential role in supporting working memory operations.Theta-band transcranial alternating current stimulation(tACS)offers a potential mechanism for working memory enhancement through direct modulation of these fundamental neural oscillations.Nevertheless,current empirical evidence shows substantial variability in the observed effects of theta-tACS across studies.AIM To conduct a systematic review and meta-analysis evaluating the effects of thetatACS on working memory performance in healthy adults.METHODS A systematic literature search was performed on PubMed,EMBASE,and Web of Science up to March 10,2025.Effect sizes were computed using Hedges’g with 95%confidence intervals(CIs),with separate meta-analyses for all included studies and for distinct working memory paradigms[n-back and delayed matchto-sample(DMTS)tasks]to examine potential task-specific effects.Subgroup analyses and meta-regression were performed to evaluate the influence of key moderating variables.RESULTS The systematic review included 21 studies(67 effect sizes).Initial meta-analysis showed theta-tACS moderately improved working memory(Hedges’g=0.405,95%CI:0.212-0.598).However,this effect became nonsignificant after correcting for publication bias(trim-and-fill adjusted Hedges’g=0.082,95%CI:-0.052 to 0.217).Task-specific analyses revealed significant benefits in n-back tasks(Hedges’g=0.463,95%CI:0.193-0.733)but not in DMTS tasks(Hedges’g=0.257,95%CI:-0.186 to 0.553).Moderator analyses showed that performance in n-back tasks was influenced by stimulation frequency(P=0.001),concurrent status(P=0.014),task modality(P=0.005),and duration(P=0.013),whereas only the region of targeted stimulation(P=0.012)moderated DMTS tasks.CONCLUSION Theta-tACS enhances working memory in healthy adults,with effects modulated by the task type and protocol parameters,offering dual implications for cognitive enhancement and clinical interventions.
基金supported by the National Natural Science Foundation of China(No.52265054)the Inner Mongolia Autonomous Region Natural Science Foundation Project(No.2022ZD03)+3 种基金the Inner Mongolia Autonomous Region Science and Technology Plan Project(No.2020GG0313)the Inner Mongolia Autonomous Region Natural Science Foundation Doctoral Fund Project,(No.2021BS05016)the Construction project of integrated research and development platform for key technologies in the development and processing of new nonferrous metal materials(No.RZ2300001971)the Basic Research Business Fee Project for Autonomous Region Directly Affiliated Universities(Nos.JY20220199 and JY20220028).
文摘An alternating magnetic field(AMF)was introduced into the narrow gap laser-arc hybrid welding process for 2205 duplex stainless steel thick plates.The corrosion performance of the welded joints was evaluated through electrochemical studies.The results revealed that joints welded with the application of AMF had a lower corrosion current density compared to those welded without an external AMF.Additionally,these joints showed higher pitting potential and polarization resistance.Microscopic electrochemical analysis indicated that joints subjected to AMF exhibited minimal cathodic current in simulated seawater,with only slight fluctuations in the anodic current peak.Overall,the corrosion levels on the joint surfaces were relatively low.After 4 h of immersion in the corrosive medium,the average impedance of joints exposed to AMF increased by 60.7%compared to those not influenced by a magnetic field.These findings suggest that applying AMF during the narrow gap laser-arc hybrid welding process can significantly improve the corrosion resistance of duplex stainless steel welded joints,reducing their susceptibility to stress corrosion in seawater-like environments.
基金supported by the National Natural Science Foundation of China(62371225).
文摘The Global Position System(GPS)is a reliable method for positioning in most scenarios,but it falls short in harsh environments like urban vehicular scenarios,where numerous trees or flyovers obstruct the signals.This presents an unprecedented challenge for autonomous vehicles or applications requiring high accuracy.Fortunately,vehicular ad-hoc networks(VANET)offer an effective solution,where vehicle-to-vehicle(V2V)and vehicle-to-infrastructure(V2I)communications are used to enhance location awareness.In V2I communications,the roadside units(RSU)transmit beacon packets,and the vehicle receives numerous packets from different RSUs to establish communication.To further improve localization accuracy,a cross-covariance matrices-alternating least square(CCM-ALS)algorithm is proposed.The algorithm relies on ALS of the CCM for obtaining the position of vehicles in V2I communications.The algorithm is highly precise compared to traditional angle of arrival(AOA)positioning and not inferior to direct position determination(DPD)approaches while being low in complexity,which is crucial for moving vehicles.The numerical results verify the superiority of the proposed method.
基金supported by the National Natural Science Foundation of China(Grant Nos.62371069,62372048,and 62272056)BUPT Excellent Ph.D.Students Foundation(Grant No.CX2023123)。
文摘The quantum alternating operator ansatz algorithm(QAOA+)is widely used for constrained combinatorial optimization problems(CCOPs)due to its ability to construct feasible solution spaces.In this paper,we propose a progressive quantum algorithm(PQA)to reduce qubit requirements for QAOA+in solving the maximum independent set(MIS)problem.PQA iteratively constructs a subgraph likely to include the MIS solution of the original graph and solves the problem on it to approximate the global solution.Specifically,PQA starts with a small-scale subgraph and progressively expands its graph size utilizing heuristic expansion strategies.After each expansion,PQA solves the MIS problem on the newly generated subgraph using QAOA+.In each run,PQA repeats the expansion and solving process until a predefined stopping condition is reached.Simulation results show that PQA achieves an approximation ratio of 0.95 using only 5.57%(2.17%)of the qubits and 17.59%(6.43%)of the runtime compared with directly solving the original problem with QAOA+on Erd?s-Rényi(3-regular)graphs,highlighting the efficiency and scalability of PQA.
基金supported by the Botha-Chan Research Fund,the Office of the Assistant Secretary of Defense for Health Affairs through award no.HT9425-24-1-0623(I.R.)the Brain Tumor Funders'Collaborative,the Ellie Kavalieros DIPG Research Fund+6 种基金the UPMC Children’s Hospital of Pittsburgh Foundation(G.K.,I.R.)the Children’s Brain Tumor Network(I.F.P.),a stipend from the Central South University Xiangya School of Medicine and University of Pittsburgh(Z.X.)by grant NS117742 from the National Institute of Health(T.G.F.)support from the Jesse H.&Mary Jones Gibbs Endowed Chair(T.G.F)supported in part by the University of Pittsburgh Center for Research Computing,RRID:SCR_022735through NIH award number S10OD028483Work performed in the UPMC Hillman Cancer Center Tissue and Research Pathology Services Shared Resource Facility and the services and instruments used in this project were supported,in part,by the University of Pittsburgh and the NCI of the NIH under Award Number P30CA047904.
文摘Glioblastoma(GBM)is an aggressive brain tumor with limited treatment options and a dismal prognosis.While immunotherapy has shown promise in treating some solid tumors,the treatment of GBM has been mostly unsuccessful because of a lack of targetable tumor antigens and high tumor heterogeneity.Here,we report RCAN1-4 as a novel tumor antigen derived from alternative splicing induced by the transcription factor C/EBPβ.Both C/EBPβand RCAN1-4 are highly expressed in GBM and glioma stem cells as mesenchymal subtype hallmarks.We report an immunogenic HLA-A24-specific splicing junction epitope within exon 4 and exon 5 that is unique to RCAN1-4.This epitope was validated for its ability to stimulate T cell responses in HLA-A24^(+)donors and GBM patients,leading us to identify RCAN1-4-reactive T cell receptors(TCRs)for the construction of TCR-engineered T cells(TCR-T cells).Functional studies of TCR-Ts demonstrated the in vitro and in vivo killing of RCAN1-4pos GBM tumor cells,highlighting its potential as an immunotherapeutic target in mesenchymal GBM.
基金supported by the National Natural Science Foundation of China(31800542)Natural Science Foundation of Heilongjiang Province(LH2023C105)Heilongjiang Research Institutes Basic Research Funding Project(LKSB2024-9)。
文摘The ectomycorrhizal fungus Paxillus involutus was inoculated onto tissue-cultures of the hybrid poplar,Populus davidiana×P.bolleana,to evaluate the elemental defense effect to heavy metals copper and cadmium at different concentrations by simulating Alternaria alternata fungus infection.The enrichment capacity of Populus davidiana×P.bolleana for Cu and Cd was closely associated with the degree of heavy metal stress.There was a significant positive interaction of applying Cu and Cd and the inoculation with P.involutus on A.alternata leaf blight disease index.The incidence rate and disease index of leaf blight underwent a significant reduction compared with the controls.Similarly,the ratio of the area of disease spot to leaf area,incidence rate,and disease index for Populus davidiana×P.bolleana leaves inoculated with Paxillus involutus(Batsch)Fr.were significantly lower than those of their nonmycorrhizal counterparts.With increasing the degree of Cu and Cd stress,a gradual increase in the average value of the membership function for the incidence rate and disease index was observed,indicating the weakened pathogen's ability to cause infection and the improved resistance of Populus davidiana×P.bolleana to leaf blight disease under Cu and Cd stress.Moreover,superoxide dismutase enzyme activity in Populus davidiana×P.bolleana increased significantly,reaching levels of 411.0 U/g FW and 421.6 U/g FW under Cu and Cd treatments,respectively.These changes in metabolic products and antioxidant enzyme activities suggest that P.involutus may enhance the resistance of Populus davidiana×P.bolleana to the fungus,Alternaria alternata Fr.Keissel under heavy metal stress by modulating these physiological indicators.
基金supported by the Natural Science Foundation of Jiangsu Province,China(BK20241931 and BK 20221371)the National Natural Science Foundation of China(32071943,32372214,and 31901444)the National Key Research and Development Program of China(2022YFD2300304)。
文摘Alternate wetting and drying irrigation(AWD)significantly influences the cooking and eating quality of rice(Oryza sativa L.).However,the mechanisms by which AWD affects rice cooking and eating quality remain unclear.Lipid and free fatty acid contents in grains correlate positively with cooking and eating quality of rice.This study examined Yangdao 6(YD6,a conventional taste indica inbred)and Nanjing 9108(NJ9108,a superior taste japonica inbred)cultivated under conventional irrigation(CI),alternate wetting and moderate drying irrigation(AWMD),and alternate wetting and severe drying irrigation(AWSD)from 10 days after transplanting to maturity.The research investigated the relationship between lipid and free fatty acid biosynthesis in grains and the cooking and eating quality of rice.Compared to CI treatment,AWMD significantly enhanced the contents of lipid,total free fatty acids(TFFAs),free unsaturated fatty acids(FUFAs),linoleic acid,and oleic acid in milled rice by increasing activities of enzymes associated with lipid synthesis,while AWSD produced opposite effects.Correlation analysis revealed that elevated levels of lipid,TFFAs,FUFAs,linoleic acid,and oleic acid contribute to improved rice cooking and eating quality.The findings demonstrate that AWMD enhances cooking and eating quality of milled rice through optimization of lipid and fatty acid synthesis in rice grains.
基金The Scientific Research Foundation of Nanjing University of Posts and Telecommunications(No.NY210049)
文摘A novel algorithm, i.e. the fast alternating direction method of multipliers （ADMM）, is applied to solve the classical total-variation （ TV ）-based model for image reconstruction. First, the TV-based model is reformulated as a linear equality constrained problem where the objective function is separable. Then, by introducing the augmented Lagrangian function, the two variables are alternatively minimized by the Gauss-Seidel idea. Finally, the dual variable is updated. Because the approach makes full use of the special structure of the problem and decomposes the original problem into several low-dimensional sub-problems, the per iteration computational complexity of the approach is dominated by two fast Fourier transforms. Elementary experimental results indicate that the proposed approach is more stable and efficient compared with some state-of-the-art algorithms.
文摘The effects of alternating magnetic field on the corrosion morphologies, corrosion rate, and corrosion products of copper in 3.5% NaCl solution, sea water, and magnetized sea water were investigated using electrochemical test, scanning electron microscopy/energy dispersive analysis system of X-ray （SEM/EDAX）, and X-ray diffraction （XRD）. The results show that the corrosion rate of copper in magnetized sea water is minimal. Moreover, the surface of the specimen in magnetized sea water is uniform and compact as compared with those in 3.5% NaCl solution and sea water. The corrosion products of copper in magnetized sea water are mainly Cu2O and CuCl2. However, the corrosion products in sea water are CuCl, Cu2Cl（OH）3, and FeCl3-6H2O. The electrochemical corrosion mechanisms of copper in the three media were also discussed.
基金the National High Technology Research and Development Program of China(Grant No.2012AA011603)
文摘Linear scan computed tomography （LCT） is of great benefit to online industrial scanning and security inspection due to its characteristics of straight-line source trajectory and high scanning speed. However, in practical applications of LCT, there are challenges to image reconstruction due to limited-angle and insufficient data. In this paper, a new reconstruction algorithm based on total-variation （TV） minimization is developed to reconstruct images from limited-angle and insufficient data in LCT. The main idea of our approach is to reformulate a TV problem as a linear equality constrained problem where the objective function is separable, and then minimize its augmented Lagrangian function by using alternating direction method （ADM） to solve subproblems. The proposed method is robust and efficient in the task of reconstruction by showing the convergence of ADM. The numerical simulations and real data reconstructions show that the proposed reconstruction method brings reasonable performance and outperforms some previous ones when applied to an LCT imaging problem.
基金sponsored by the Projects in the National Science & Technology Pillar Program during the Twelfth Five-year Plan Period(Grant No.2011BAK06B01)
文摘With rapid economic development in China, demand for energy and transportation is growing. Due to the limitations of factors such as terrain and traffic, a large number of buried oil and gas pipelines are parallel to high- voltage transmission lines and electrified railways over long distances. Alternating pipelines is very serious in laboratory experiments were current （AC） corrosion of such cases. In this work, carried out with an electrochemical method in a simulated soil solution at various AC current densities from 0 to 200 A]m2 and AC frequencies from 10 to 200 Hz. Experimental results indicated that with an increase in the AC current density, the corrosion po- tential of an X60 steel electrode shifted negatively, the anodic current density increased significantly, and the corrosion rate increased. Moreover, with an increase in the AC frequency, the corrosion potential of the X60 electrode shifted positively and the anodic current density decreased, which led to a decrease in the corrosion rate. Furthermore, the morphology of X60 electrodes indicated that uniform corrosion occurred at a low AC current density; while corrosion pits were found on the X60 electrode surface at a high AC current density, and deep corrosion pits seriously damaged the pipelines and might lead to leakage.
