Objective:To explore the efficacy of auricular acupoint pressure patch combined with modified Huangqi Decoction in treating diabetic nephropathy.Methods:60 patients with diabetic nephropathy treated in our hospital fr...Objective:To explore the efficacy of auricular acupoint pressure patch combined with modified Huangqi Decoction in treating diabetic nephropathy.Methods:60 patients with diabetic nephropathy treated in our hospital from January 2021 to December 2022 were selected for this study.The patients were randomly divided into two groups using the random number table method,with 30 patients in each group.Among them,the control group was treated with conventional Western medicine,while the experimental group was treated with auricular acupoint pressure patches combined with modified Huangqi Decoction.The patients’fasting blood glucose(FPG),2-hour postprandial blood glucose(2hPG),glycated hemoglobin(HbA1c),urinary protein quantification,urea nitrogen(BUN),serum creatinine(SCr),and other indicators were detected and recorded before and after treatment.Results:Before treatment,there was no statistically significant difference in the FPG,the 2hPG,and the HbA1c between the two groups of patients(P>0.05);after treatment,the FPG,the 2hPG,and the HbA1c of the patients in the experimental group were significantly lower than those in the control group(P<0.05).Before treatment,there was no statistically significant difference in the urinary protein quantification,the BUN,and the SCr between the two groups of patients(P>0.05);after treatment,the urinary protein quantification,BUN,and SCr of the patients in the experimental group were significantly lower than those in the control group(P<0.05).The experimental group showed better improvement in symptoms such as fatigue,backache,and frequency of nocturia(P<0.05).Conclusion:Auricular acupoint pressure patch combined with modified Huangqi Decoction effectively treats diabetic nephropathy and it helps control blood sugar and renal function indicators and improve clinical symptoms,therefore improving the patients’quality of life.展开更多
Objective:To study the effect of Traditional Chinese medicine(TCM)nursing intervention combined with acupoint patch in the treatment of acute exacerbation of chronic obstructive pulmonary disease(COPD).Methods:A total...Objective:To study the effect of Traditional Chinese medicine(TCM)nursing intervention combined with acupoint patch in the treatment of acute exacerbation of chronic obstructive pulmonary disease(COPD).Methods:A total of 60 patients with acute exacerbation of COPD admitted between September 2022 and September 2023 were selected and randomly grouped into a control group(conventional care and treatment)and an observation group(joint interventions:traditional Chinese medicine nursing interventions,acupoint compresses),with 30 patients each.The arterial blood gas indexes of the two groups,hospitalization time,pulmonary function indexes,and TCM symptom scores were analyzed and compared between the two groups.Results:The arterial oxygen pressure(PaO_(2))(9.52±1.02 kPa)and partial pressure of carbon dioxide(PaCO_(2))(5.01±1.02 kPa)of the observation group were better than those of the control group after the intervention(P<0.05).The forced expiratory volume(FEV1)(3.38±0.15%),the FEV1% prediction value(72.52±2.25),and the FEV1/forced vital capacity(FVC)(79.52±1.41%)were higher than those of the control group(P<0.05).The hospitalization time(12.16±1.02 d)and TCM symptom score(4.12±1.26)of the observation group were better than those of the control group(P<0.05).Conclusion:Significant nursing effects were achieved by carrying out combined interventions(Chinese medicine nursing intervention and acupoint application)during the acute exacerbation of COPD.展开更多
目的:观察益气温经穴位贴贴敷联合西药口服治疗绝经后骨质疏松症(postmenopausal osteoporosis,PMOP)肾虚血瘀证的临床疗效。方法:将符合要求的120例PMOP肾虚血瘀证患者随机分为2组,每组60例,分别采用单纯西药(阿仑膦酸钠片、钙尔奇D片...目的:观察益气温经穴位贴贴敷联合西药口服治疗绝经后骨质疏松症(postmenopausal osteoporosis,PMOP)肾虚血瘀证的临床疗效。方法:将符合要求的120例PMOP肾虚血瘀证患者随机分为2组,每组60例,分别采用单纯西药(阿仑膦酸钠片、钙尔奇D片、骨化三醇胶丸)口服治疗(西药治疗组)与益气温经穴位贴贴敷联合西药口服治疗(联合治疗组)。3个月为1个疗程,每个疗程之间隔1个月,共治疗3个疗程。分别于治疗前、治疗开始后6个月、治疗开始后12个月,比较2组患者的骨密度T值、血清雌二醇(estradiol,E2)水平、血清卵泡刺激素(follicle stimulating hormone,FSH)水平、血清Ⅰ型前胶原氨基端前肽(N-terminal propeptide of typeⅠprecollagen,PⅠNP)水平、血清Ⅰ型胶原羧基端肽β特殊序列(β-C-terminal telopeptide of typeⅠcollagen,β-CTX)水平、腰背部疼痛视觉模拟量表(visual analogue scale,VAS)评分、简明健康状况调查表(short form 36 health survey questionnaire,SF-36)评分。结果:①一般情况。共5例患者退出试验,其中西药治疗组3例、联合治疗组2例。最终西药治疗组纳入57例患者,联合治疗组纳入58例患者。②骨密度T值。治疗前后骨密度T值总体上随时间推移呈上升趋势(F=109.349,P=0.000),2组间差异无统计学意义(F=0.014,P=0.905)。③血清E2水平。治疗前后西药治疗组患者血清E2水平随时间推移无明显变化(F=0.790,P=0.456),联合治疗组患者血清E2水平随时间推移呈上升趋势(F=6.559,P=0.002)。治疗开始后6个月、12个月,联合治疗组患者血清E2水平均高于西药治疗组(t=-3.983,P=0.000;t=-4.177,P=0.000)。④血清FSH水平。治疗前后血清FSH水平总体上随时间推移呈下降趋势(F=17.933,P=0.000),2组间差异无统计学意义(F=1.123,P=0.291)。⑤血清PⅠNP水平。治疗前后西药治疗组患者血清PⅠNP水平随时间推移无明显变化(F=0.368,P=0.693),联合治疗组患者血清PⅠNP水平随时间推移呈上升趋势(F=11.724,P=0.000)。治疗开始后6个月、12个月,联合治疗组患者血清PⅠNP水平均高于西药治疗组(t=-5.844,P=0.000;t=-5.619,P=0.000)。⑥血清β-CTX水平。治疗前后血清β-CTX水平总体上随时间推移呈下降趋势(F=6.371,P=0.002),2组间差异无统计学意义(F=1.898,P=0.171)。⑦腰背部疼痛VAS评分。治疗前后2组患者腰背部疼痛VAS评分随时间推移均呈下降趋势(F=35.668,P=0.000;F=147.005,P=0.000)。治疗开始后6个月、12个月,联合治疗组患者腰背部疼痛VAS评分均低于西药治疗组(t=12.848,P=0.000;t=13.291,P=0.000)。⑧SF-36评分。治疗前后2组患者SF-36评分随时间推移均呈上升趋势(F=54.622,P=0.000;F=105.957,P=0.000)。治疗开始后6个月、12个月,联合治疗组患者SF-36评分均高于西药治疗组(t=-10.331,P=0.000;t=-10.323,P=0.000)。结论:益气温经穴位贴贴敷联合西药口服治疗PMOP肾虚血瘀证,在提高血清E2水平、促进骨形成、减轻腰背部疼痛、改善患者生活质量方面优于单纯西药口服治疗;但两者在降低血清FSH水平、抑制骨吸收、提高骨密度方面的效果相当。展开更多
目的:观察穴位针刺联合三伏贴治疗老年膝骨关节炎(knee osteoarthritis,KOA)的临床疗效及对患者血清骨代谢与Lequesnse指数的影响。方法:选取2022年7月至2023年7月江西中医药大学第二附属医院诊治的KOA患者100例,按照随机数字表法分为...目的:观察穴位针刺联合三伏贴治疗老年膝骨关节炎(knee osteoarthritis,KOA)的临床疗效及对患者血清骨代谢与Lequesnse指数的影响。方法:选取2022年7月至2023年7月江西中医药大学第二附属医院诊治的KOA患者100例,按照随机数字表法分为对照组和联合组,每组50例。两组患者均进行基础康复训练,对照组另给予三伏贴贴敷治疗,联合组在对照组治疗的基础上给予穴位针刺治疗。观察两组患者临床疗效、不良反应发生率、中医证候评分、Lysholm功能评分、Lequesnse指数,检测两组患者治疗前后血清骨钙素(bone glaprotein,BGP)、骨保护素(osteoprotegerin,OPG)、I型胶原C端肽(C-telopeptide of type I collagen,CTX-Ⅰ)、白细胞介素(interleukin,IL)-1、基质金属蛋白酶(matrix metalloproteinase,MMP)-3、肿瘤坏死因子(tumor necrosis factor,TNF)-α水平。结果:两组KOA患者治疗后中医证候评分、Lequesnse指数降低、Lysholm功能评分均优于治疗前(P<0.05),且联合组治疗后中医证候评分和Lequesnse指数低于对照组,Lysholm功能评分高于对照组,差异有统计学意义(P<0.05);联合组治疗后BGP、OPG水平高于对照组,CTX-I水平低于对照组,差异有统计学意义(P<0.05);联合组治疗后IL-1、MMP-3、TNF-α水平低于对照组,差异有统计学意义(P<0.05);联合组有效率为92.00%,对照组有效率为76.00%,联合组有效率高于对照组,差异有统计学意义(P<0.05);对照组不良反应发生率为8%,联合组不良反应发生率为4%,两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论:穴位针刺联合三伏贴治疗老年KOA,可调节血清炎症因子水平与骨代谢指标,降低Lequesnse指数,改善患者骨关节功能,提高患者生活质量,且不良反应发生率较低。展开更多
文摘Objective:To explore the efficacy of auricular acupoint pressure patch combined with modified Huangqi Decoction in treating diabetic nephropathy.Methods:60 patients with diabetic nephropathy treated in our hospital from January 2021 to December 2022 were selected for this study.The patients were randomly divided into two groups using the random number table method,with 30 patients in each group.Among them,the control group was treated with conventional Western medicine,while the experimental group was treated with auricular acupoint pressure patches combined with modified Huangqi Decoction.The patients’fasting blood glucose(FPG),2-hour postprandial blood glucose(2hPG),glycated hemoglobin(HbA1c),urinary protein quantification,urea nitrogen(BUN),serum creatinine(SCr),and other indicators were detected and recorded before and after treatment.Results:Before treatment,there was no statistically significant difference in the FPG,the 2hPG,and the HbA1c between the two groups of patients(P>0.05);after treatment,the FPG,the 2hPG,and the HbA1c of the patients in the experimental group were significantly lower than those in the control group(P<0.05).Before treatment,there was no statistically significant difference in the urinary protein quantification,the BUN,and the SCr between the two groups of patients(P>0.05);after treatment,the urinary protein quantification,BUN,and SCr of the patients in the experimental group were significantly lower than those in the control group(P<0.05).The experimental group showed better improvement in symptoms such as fatigue,backache,and frequency of nocturia(P<0.05).Conclusion:Auricular acupoint pressure patch combined with modified Huangqi Decoction effectively treats diabetic nephropathy and it helps control blood sugar and renal function indicators and improve clinical symptoms,therefore improving the patients’quality of life.
文摘Objective:To study the effect of Traditional Chinese medicine(TCM)nursing intervention combined with acupoint patch in the treatment of acute exacerbation of chronic obstructive pulmonary disease(COPD).Methods:A total of 60 patients with acute exacerbation of COPD admitted between September 2022 and September 2023 were selected and randomly grouped into a control group(conventional care and treatment)and an observation group(joint interventions:traditional Chinese medicine nursing interventions,acupoint compresses),with 30 patients each.The arterial blood gas indexes of the two groups,hospitalization time,pulmonary function indexes,and TCM symptom scores were analyzed and compared between the two groups.Results:The arterial oxygen pressure(PaO_(2))(9.52±1.02 kPa)and partial pressure of carbon dioxide(PaCO_(2))(5.01±1.02 kPa)of the observation group were better than those of the control group after the intervention(P<0.05).The forced expiratory volume(FEV1)(3.38±0.15%),the FEV1% prediction value(72.52±2.25),and the FEV1/forced vital capacity(FVC)(79.52±1.41%)were higher than those of the control group(P<0.05).The hospitalization time(12.16±1.02 d)and TCM symptom score(4.12±1.26)of the observation group were better than those of the control group(P<0.05).Conclusion:Significant nursing effects were achieved by carrying out combined interventions(Chinese medicine nursing intervention and acupoint application)during the acute exacerbation of COPD.
文摘[目的]系统评价不同中医适宜技术对寒湿痹阻型膝痹病患者的干预效果,为临床实践提供循证依据。[方法]检索英文数据库PubMed、Web of Science Core Collection、CINAHL Complete、Embase、Science Direct、Cochrane Library,中文数据库中国知网、万方、维普和中国生物医学文献数据库中关于中医适宜技术对寒湿痹阻型膝痹病患者干预效果的文献,检索时限为2019年1月1日至2024年7月18日,由2名研究者独立筛选文献,并进行资料提取和文献质量评价。采用RevMan 5.4软件进行传统Meta分析,Stata 17.0软件进行网状Meta分析。[结果]最终纳入33项研究,共3154例患者,13种中医适宜技术。网状Meta分析显示,穴位贴敷联合中药熏洗改善膝关节症状的效果最好,累计排序概率图下面积(surface under the cumulative ranking,SUCRA)为92.7%;艾灸联合中药离子导入在提高临床总有效率方面效果最好,SUCRA为86.8%。[结论]现有研究表明,穴位贴敷联合中药熏洗能有效改善寒湿痹阻型膝痹病患者膝关节症状,艾灸联合中药离子导入能有效提高临床总有效率,且联合使用不同的中医适宜技术较单一使用效果较好。建议临床医护人员可在中医辨证基础之上,制定多样化的中医适宜技术干预方案,以提高寒湿痹阻型膝痹病患者的临床疗效和护理质量。
文摘目的:观察益气温经穴位贴贴敷联合西药口服治疗绝经后骨质疏松症(postmenopausal osteoporosis,PMOP)肾虚血瘀证的临床疗效。方法:将符合要求的120例PMOP肾虚血瘀证患者随机分为2组,每组60例,分别采用单纯西药(阿仑膦酸钠片、钙尔奇D片、骨化三醇胶丸)口服治疗(西药治疗组)与益气温经穴位贴贴敷联合西药口服治疗(联合治疗组)。3个月为1个疗程,每个疗程之间隔1个月,共治疗3个疗程。分别于治疗前、治疗开始后6个月、治疗开始后12个月,比较2组患者的骨密度T值、血清雌二醇(estradiol,E2)水平、血清卵泡刺激素(follicle stimulating hormone,FSH)水平、血清Ⅰ型前胶原氨基端前肽(N-terminal propeptide of typeⅠprecollagen,PⅠNP)水平、血清Ⅰ型胶原羧基端肽β特殊序列(β-C-terminal telopeptide of typeⅠcollagen,β-CTX)水平、腰背部疼痛视觉模拟量表(visual analogue scale,VAS)评分、简明健康状况调查表(short form 36 health survey questionnaire,SF-36)评分。结果:①一般情况。共5例患者退出试验,其中西药治疗组3例、联合治疗组2例。最终西药治疗组纳入57例患者,联合治疗组纳入58例患者。②骨密度T值。治疗前后骨密度T值总体上随时间推移呈上升趋势(F=109.349,P=0.000),2组间差异无统计学意义(F=0.014,P=0.905)。③血清E2水平。治疗前后西药治疗组患者血清E2水平随时间推移无明显变化(F=0.790,P=0.456),联合治疗组患者血清E2水平随时间推移呈上升趋势(F=6.559,P=0.002)。治疗开始后6个月、12个月,联合治疗组患者血清E2水平均高于西药治疗组(t=-3.983,P=0.000;t=-4.177,P=0.000)。④血清FSH水平。治疗前后血清FSH水平总体上随时间推移呈下降趋势(F=17.933,P=0.000),2组间差异无统计学意义(F=1.123,P=0.291)。⑤血清PⅠNP水平。治疗前后西药治疗组患者血清PⅠNP水平随时间推移无明显变化(F=0.368,P=0.693),联合治疗组患者血清PⅠNP水平随时间推移呈上升趋势(F=11.724,P=0.000)。治疗开始后6个月、12个月,联合治疗组患者血清PⅠNP水平均高于西药治疗组(t=-5.844,P=0.000;t=-5.619,P=0.000)。⑥血清β-CTX水平。治疗前后血清β-CTX水平总体上随时间推移呈下降趋势(F=6.371,P=0.002),2组间差异无统计学意义(F=1.898,P=0.171)。⑦腰背部疼痛VAS评分。治疗前后2组患者腰背部疼痛VAS评分随时间推移均呈下降趋势(F=35.668,P=0.000;F=147.005,P=0.000)。治疗开始后6个月、12个月,联合治疗组患者腰背部疼痛VAS评分均低于西药治疗组(t=12.848,P=0.000;t=13.291,P=0.000)。⑧SF-36评分。治疗前后2组患者SF-36评分随时间推移均呈上升趋势(F=54.622,P=0.000;F=105.957,P=0.000)。治疗开始后6个月、12个月,联合治疗组患者SF-36评分均高于西药治疗组(t=-10.331,P=0.000;t=-10.323,P=0.000)。结论:益气温经穴位贴贴敷联合西药口服治疗PMOP肾虚血瘀证,在提高血清E2水平、促进骨形成、减轻腰背部疼痛、改善患者生活质量方面优于单纯西药口服治疗;但两者在降低血清FSH水平、抑制骨吸收、提高骨密度方面的效果相当。
文摘目的:观察穴位针刺联合三伏贴治疗老年膝骨关节炎(knee osteoarthritis,KOA)的临床疗效及对患者血清骨代谢与Lequesnse指数的影响。方法:选取2022年7月至2023年7月江西中医药大学第二附属医院诊治的KOA患者100例,按照随机数字表法分为对照组和联合组,每组50例。两组患者均进行基础康复训练,对照组另给予三伏贴贴敷治疗,联合组在对照组治疗的基础上给予穴位针刺治疗。观察两组患者临床疗效、不良反应发生率、中医证候评分、Lysholm功能评分、Lequesnse指数,检测两组患者治疗前后血清骨钙素(bone glaprotein,BGP)、骨保护素(osteoprotegerin,OPG)、I型胶原C端肽(C-telopeptide of type I collagen,CTX-Ⅰ)、白细胞介素(interleukin,IL)-1、基质金属蛋白酶(matrix metalloproteinase,MMP)-3、肿瘤坏死因子(tumor necrosis factor,TNF)-α水平。结果:两组KOA患者治疗后中医证候评分、Lequesnse指数降低、Lysholm功能评分均优于治疗前(P<0.05),且联合组治疗后中医证候评分和Lequesnse指数低于对照组,Lysholm功能评分高于对照组,差异有统计学意义(P<0.05);联合组治疗后BGP、OPG水平高于对照组,CTX-I水平低于对照组,差异有统计学意义(P<0.05);联合组治疗后IL-1、MMP-3、TNF-α水平低于对照组,差异有统计学意义(P<0.05);联合组有效率为92.00%,对照组有效率为76.00%,联合组有效率高于对照组,差异有统计学意义(P<0.05);对照组不良反应发生率为8%,联合组不良反应发生率为4%,两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论:穴位针刺联合三伏贴治疗老年KOA,可调节血清炎症因子水平与骨代谢指标,降低Lequesnse指数,改善患者骨关节功能,提高患者生活质量,且不良反应发生率较低。
