Natural long-chain alkanol and alkyl carboxylic acid were used to prepare novel hydrophobic deep eutectic solvents(HDESs).These HDESs are liquid at room temperature and have low viscosity(<12.26 mPa·s),low pol...Natural long-chain alkanol and alkyl carboxylic acid were used to prepare novel hydrophobic deep eutectic solvents(HDESs).These HDESs are liquid at room temperature and have low viscosity(<12.26 mPa·s),low polarity(lower than that of methanol,ChCl-based deep eutectic solvents and other reported HDESs),and low density(<0.928 g/mL).A simple one-pot method based on a novel HDES-water two-phase extraction system was constructed for the extraction of weak-polarity bioactive components,anthraquinones,from Rhei Radix et Rhizoma.This HDES-based new extraction method does not consume hazardous organic solvents and can obtain a total anthraquinone yield of 21.52 mg/g,which is close to that obtained by the Chinese pharmacopoeia method(21.22 mg/g)and considerably higher than those by other reported HDESs-based extraction methods(14.20-20.09 mg/g,p<0.01).The high extraction yield can be mainly attributed to the severe destruction of the RRR cell walls by the extraction system and the excellent dissolving ability of novel HDESs for anthraquinones.展开更多
Excess molar volume(V E) data on binary liquid mixtures of methylheptenone (MHO) with methanol, ethanol, n-propanol or n-butanol have been determined from the density measurements at 298.15 K and atmospheric pressure...Excess molar volume(V E) data on binary liquid mixtures of methylheptenone (MHO) with methanol, ethanol, n-propanol or n-butanol have been determined from the density measurements at 298.15 K and atmospheric pressure. The values of V E in all the systems over the entire composition range are quantified by the Redlich-Kister equation. The effects of the chain length of alkanols on V E are discussed.展开更多
bInstitute of Chemistry, Chinese Academy of Sciences, Beijing 100080, China Solubilities of tetraphenylarsonium tetraphenylborate (Ph 4AsB Ph 4) in water, methanol, ethanol, 1 propanol, 1 butanol, 1 pentanol,...bInstitute of Chemistry, Chinese Academy of Sciences, Beijing 100080, China Solubilities of tetraphenylarsonium tetraphenylborate (Ph 4AsB Ph 4) in water, methanol, ethanol, 1 propanol, 1 butanol, 1 pentanol, 1 hexanol and 1 octanol at T =293.2, 298.2, 303.2 and 308.2 K have been determined by spectrophotometry. The standard transfer Gibbs energy ( Δ tr G 0 w→s ) and entropy ( Δ tr S 0 w→s ) of Ph 4AsBPh 4 from water to the n alkanols at temerature from 293.2 K to 308.2 K have been obtained. Furthermore, the contribution of microscopic interaction to the standard Gibbs energy of transfer for Ph 4AsBPh 4 was calculated and discussed. The results show that the effect of hydrophobic interaction of Ph 4AsBPh 4 on its transfer process is the most important factor. According to the thermodynamical principle, the transfer process of Ph 4AsBPh 4 from water to the n alkanols is the entropy dominanted.展开更多
The molecular volumes of dioxins,organic phosphorous compounds and n-alkanols were computed at the B3LYP/6-311G** level,and were then correlated with their toxicity.It was surprisingly found that there exists the so-c...The molecular volumes of dioxins,organic phosphorous compounds and n-alkanols were computed at the B3LYP/6-311G** level,and were then correlated with their toxicity.It was surprisingly found that there exists the so-called“critical volume of toxicity”(CVT)in each series of compound of the present study,i.e.the toxicity increases with increase of the molecular volume when less than CVT,while decreasing with increase of the molecular volume when lar-ger than CVT.The CVT for the three series of compounds is quite similar,ranging 0.309—0.320nm3.It was proposed that the ordinary linear solvation energy relationship (LSER) should be modified with respect to the new findings,and ac-cordingly the anaesthetic potency of partial fluorinated n-alkanols was predicted.展开更多
基金the National Natural Science Foundation of China (Grant Nos.: 81673394 and 82073811)the Fundamental Research Funds for the Central Universities (Grant No.: 2042020kf1010)the Large-scale Instrument and Equipment Sharing Foundation of Wuhan University (Grant No.: LF20170838)
文摘Natural long-chain alkanol and alkyl carboxylic acid were used to prepare novel hydrophobic deep eutectic solvents(HDESs).These HDESs are liquid at room temperature and have low viscosity(<12.26 mPa·s),low polarity(lower than that of methanol,ChCl-based deep eutectic solvents and other reported HDESs),and low density(<0.928 g/mL).A simple one-pot method based on a novel HDES-water two-phase extraction system was constructed for the extraction of weak-polarity bioactive components,anthraquinones,from Rhei Radix et Rhizoma.This HDES-based new extraction method does not consume hazardous organic solvents and can obtain a total anthraquinone yield of 21.52 mg/g,which is close to that obtained by the Chinese pharmacopoeia method(21.22 mg/g)and considerably higher than those by other reported HDESs-based extraction methods(14.20-20.09 mg/g,p<0.01).The high extraction yield can be mainly attributed to the severe destruction of the RRR cell walls by the extraction system and the excellent dissolving ability of novel HDESs for anthraquinones.
基金Supported by the National Natural Science Foundation of China( No.2 99760 3 5 ) and the Zhejiang Provincial NatioralScience Foundation of China( No.2 990 3 5 )
文摘Excess molar volume(V E) data on binary liquid mixtures of methylheptenone (MHO) with methanol, ethanol, n-propanol or n-butanol have been determined from the density measurements at 298.15 K and atmospheric pressure. The values of V E in all the systems over the entire composition range are quantified by the Redlich-Kister equation. The effects of the chain length of alkanols on V E are discussed.
文摘bInstitute of Chemistry, Chinese Academy of Sciences, Beijing 100080, China Solubilities of tetraphenylarsonium tetraphenylborate (Ph 4AsB Ph 4) in water, methanol, ethanol, 1 propanol, 1 butanol, 1 pentanol, 1 hexanol and 1 octanol at T =293.2, 298.2, 303.2 and 308.2 K have been determined by spectrophotometry. The standard transfer Gibbs energy ( Δ tr G 0 w→s ) and entropy ( Δ tr S 0 w→s ) of Ph 4AsBPh 4 from water to the n alkanols at temerature from 293.2 K to 308.2 K have been obtained. Furthermore, the contribution of microscopic interaction to the standard Gibbs energy of transfer for Ph 4AsBPh 4 was calculated and discussed. The results show that the effect of hydrophobic interaction of Ph 4AsBPh 4 on its transfer process is the most important factor. According to the thermodynamical principle, the transfer process of Ph 4AsBPh 4 from water to the n alkanols is the entropy dominanted.
文摘The molecular volumes of dioxins,organic phosphorous compounds and n-alkanols were computed at the B3LYP/6-311G** level,and were then correlated with their toxicity.It was surprisingly found that there exists the so-called“critical volume of toxicity”(CVT)in each series of compound of the present study,i.e.the toxicity increases with increase of the molecular volume when less than CVT,while decreasing with increase of the molecular volume when lar-ger than CVT.The CVT for the three series of compounds is quite similar,ranging 0.309—0.320nm3.It was proposed that the ordinary linear solvation energy relationship (LSER) should be modified with respect to the new findings,and ac-cordingly the anaesthetic potency of partial fluorinated n-alkanols was predicted.
