The effects of highly active antiretroviral therapy （HAART） to patients with AIDS in Hubei province of China were investigated in order to provide scientific evidence to reinforce the management of HAART. Self-made ...The effects of highly active antiretroviral therapy （HAART） to patients with AIDS in Hubei province of China were investigated in order to provide scientific evidence to reinforce the management of HAART. Self-made questionnaires and descriptive method of epidemiology were used to collect and describe the changes of clinical symptoms, HIV RIgA concentration, and immune function of patients with AIDS. After HAART, the effective rate of fever, cough, diarrhea, lymphadenectasis, weight loss, tetter, debility and fimgous infection was 92.4%, 90.85%, 92.91%, 90.73%, 93.69%, 89.04%, 92.34%, and 83.1%, respectively. Of 117 patients with detected HIV RNA concentration, 41.03% had declined over 0.5 log, and 52.99% less than 0.5 log. CD4^＋T cell count was obviously increased： the average number after HAART for 3 or 6 months was 237μL （26-755μL） and 239μL （17-833μL）, respectively HAART can improve AIDS patients＇ clinical symptoms, reduce HIV RNA concentration, and maintain immune function. It is very important for the effectiveness of HAART to raise clinical adherence of pa- tients with AIDS and have a persistent surveillance.展开更多
The HIV/AIDS epidemic in China is spreading rapidly,with the number of people living with HIV(PLHIV)increasing nearly 1.5 times from 0.44 million in 2011 to 1.05 million in 2020^([1,2]).Antiretroviral therapy(ART)is t...The HIV/AIDS epidemic in China is spreading rapidly,with the number of people living with HIV(PLHIV)increasing nearly 1.5 times from 0.44 million in 2011 to 1.05 million in 2020^([1,2]).Antiretroviral therapy(ART)is the main AIDS treatment and can effectively reduce HIV transmission,morbidity.展开更多
文摘The effects of highly active antiretroviral therapy （HAART） to patients with AIDS in Hubei province of China were investigated in order to provide scientific evidence to reinforce the management of HAART. Self-made questionnaires and descriptive method of epidemiology were used to collect and describe the changes of clinical symptoms, HIV RIgA concentration, and immune function of patients with AIDS. After HAART, the effective rate of fever, cough, diarrhea, lymphadenectasis, weight loss, tetter, debility and fimgous infection was 92.4%, 90.85%, 92.91%, 90.73%, 93.69%, 89.04%, 92.34%, and 83.1%, respectively. Of 117 patients with detected HIV RNA concentration, 41.03% had declined over 0.5 log, and 52.99% less than 0.5 log. CD4^＋T cell count was obviously increased： the average number after HAART for 3 or 6 months was 237μL （26-755μL） and 239μL （17-833μL）, respectively HAART can improve AIDS patients＇ clinical symptoms, reduce HIV RNA concentration, and maintain immune function. It is very important for the effectiveness of HAART to raise clinical adherence of pa- tients with AIDS and have a persistent surveillance.
基金supported by the National Natural Science Foundation of China [Grant No.72104008]
文摘The HIV/AIDS epidemic in China is spreading rapidly,with the number of people living with HIV(PLHIV)increasing nearly 1.5 times from 0.44 million in 2011 to 1.05 million in 2020^([1,2]).Antiretroviral therapy(ART)is the main AIDS treatment and can effectively reduce HIV transmission,morbidity.
