Polar semiconductors,particularly the emerging polar two-dimensional(2D)halide perovskites,have motivated immense interest in diverse photoelectronic devices due to their distinguishing polarizationgenerated photoelec...Polar semiconductors,particularly the emerging polar two-dimensional(2D)halide perovskites,have motivated immense interest in diverse photoelectronic devices due to their distinguishing polarizationgenerated photoelectric effects.However,the constraints on the organic cation's choice are still subject to limitations of polar 2D halide perovskites due to the size of the inorganic pocket between adjacent corner-sharing octahedra.Herein,a mixed spacer cation ordering strategy is employed to assemble a polar 2D halide perovskite NMAMAPb Br_(4)(NMPB,NMA is N-methylbenzene ammonium,MA is methylammonium)with alternating cation in the interlayer space.Driven by the incorporation of a second MA cation,the perovskite layer transformed from a 2D Pb_(7)Br_(24)anionic network with corner-and face-sharing octahedra to a flat 2D PbBr_(4)perovskite networks only with corner-sharing octahedra.In the crystal structure of NMPB,the asymmetric hydrogen-bonding interactions between ordered mixed-spacer cations and 2D perovskite layers give rise to a second harmonic generation response and a large polarization of 1.3μC/cm^(2).More intriguingly,the ordered 2D perovskite networks endow NMPB with excellent self-powered polarization-sensitive detection performance,showing a considerable polarization-related dichroism ratio up to 1.87.The reconstruction of an inorganic framework within a crystal through mixed cation ordering offers a new synthetic tool for templating perovskite lattices with controlled properties,overcoming limitations of conventional cation choice.展开更多
目的探讨急性脑梗死(acute cerebral infarction,ACI)静脉溶栓短期预后的影响因素。方法选取2018年6月至2021年4月如皋市人民医院收治的83例ACI患者,收集患者临床资料,于患者入院24 h内检测外周血中性粒细胞与淋巴细胞比值(neutrophil t...目的探讨急性脑梗死(acute cerebral infarction,ACI)静脉溶栓短期预后的影响因素。方法选取2018年6月至2021年4月如皋市人民医院收治的83例ACI患者,收集患者临床资料,于患者入院24 h内检测外周血中性粒细胞与淋巴细胞比值(neutrophil to lymphocyte ratio,NLR)和B型利尿钠肽(B-type natriuretic peptide,BNP)水平。于治疗2周后复查头颅CT/MRI,并结合格拉斯哥昏迷量表(Glasgow coma scale,GCS)评分将其分为预后良好组和预后不佳组。以多因素logistic回归分析探讨影响ACI静脉溶栓后短期预后不佳的影响因素。结果83例ACI患者中,预后不佳组45例,预后良好组38例。预后不佳组糖尿病史(17.8%比2.6%)、入院24 h的美国国立卫生研究院卒中量表(National Institutes of Health Stroke Scale,NIHSS)评分≥15分占比(46.7%比23.7%)及血清BNP[(264.31±76.04)pg/ml比(91.34±15.21)pg/ml]、同型半胱氨酸(homocysteine,Hcy)[(18.12±3.51)μmol/L比(14.73±3.29)μmol/L]和NLR[(2.16±0.24)比(1.69±0.35)]水平均高于预后良好组,差异有统计学意义(P<0.05)。多因素logistic回归分析显示,糖尿病史(OR=3.040,95%CI:1.176~7.861,P=0.002)、入院24 h NIHSS评分≥15分(OR=3.684,95%CI:1.425~9.524,P=0.001)及血清BNP(OR=2.835,95%CI:1.096~7.329,P=0.001)和NLR(OR=3.842,95%CI:1.486~9.933,P=0.001)水平偏高为ACI静脉溶栓后短期内预后不佳的危险因素。结论存在糖尿病史、入院24 h NIHSS评分≥15分、血清BNP及NLR水平偏高的ACI静脉溶栓患者更易出现预后不佳的情况。展开更多
基金supported by the National Natural Science Foundation of China(Nos.22193042,22125110,22075285,52473283,21921001,U21A2069)the Key Research Program of Frontier Sciences of the Chinese Academy of Sciences(No.ZDBS-LY-SLH024)the Youth Innovation Promotion of Chinese Academy of Sciences(No.2020307)。
文摘Polar semiconductors,particularly the emerging polar two-dimensional(2D)halide perovskites,have motivated immense interest in diverse photoelectronic devices due to their distinguishing polarizationgenerated photoelectric effects.However,the constraints on the organic cation's choice are still subject to limitations of polar 2D halide perovskites due to the size of the inorganic pocket between adjacent corner-sharing octahedra.Herein,a mixed spacer cation ordering strategy is employed to assemble a polar 2D halide perovskite NMAMAPb Br_(4)(NMPB,NMA is N-methylbenzene ammonium,MA is methylammonium)with alternating cation in the interlayer space.Driven by the incorporation of a second MA cation,the perovskite layer transformed from a 2D Pb_(7)Br_(24)anionic network with corner-and face-sharing octahedra to a flat 2D PbBr_(4)perovskite networks only with corner-sharing octahedra.In the crystal structure of NMPB,the asymmetric hydrogen-bonding interactions between ordered mixed-spacer cations and 2D perovskite layers give rise to a second harmonic generation response and a large polarization of 1.3μC/cm^(2).More intriguingly,the ordered 2D perovskite networks endow NMPB with excellent self-powered polarization-sensitive detection performance,showing a considerable polarization-related dichroism ratio up to 1.87.The reconstruction of an inorganic framework within a crystal through mixed cation ordering offers a new synthetic tool for templating perovskite lattices with controlled properties,overcoming limitations of conventional cation choice.
文摘目的探讨急性脑梗死(acute cerebral infarction,ACI)静脉溶栓短期预后的影响因素。方法选取2018年6月至2021年4月如皋市人民医院收治的83例ACI患者,收集患者临床资料,于患者入院24 h内检测外周血中性粒细胞与淋巴细胞比值(neutrophil to lymphocyte ratio,NLR)和B型利尿钠肽(B-type natriuretic peptide,BNP)水平。于治疗2周后复查头颅CT/MRI,并结合格拉斯哥昏迷量表(Glasgow coma scale,GCS)评分将其分为预后良好组和预后不佳组。以多因素logistic回归分析探讨影响ACI静脉溶栓后短期预后不佳的影响因素。结果83例ACI患者中,预后不佳组45例,预后良好组38例。预后不佳组糖尿病史(17.8%比2.6%)、入院24 h的美国国立卫生研究院卒中量表(National Institutes of Health Stroke Scale,NIHSS)评分≥15分占比(46.7%比23.7%)及血清BNP[(264.31±76.04)pg/ml比(91.34±15.21)pg/ml]、同型半胱氨酸(homocysteine,Hcy)[(18.12±3.51)μmol/L比(14.73±3.29)μmol/L]和NLR[(2.16±0.24)比(1.69±0.35)]水平均高于预后良好组,差异有统计学意义(P<0.05)。多因素logistic回归分析显示,糖尿病史(OR=3.040,95%CI:1.176~7.861,P=0.002)、入院24 h NIHSS评分≥15分(OR=3.684,95%CI:1.425~9.524,P=0.001)及血清BNP(OR=2.835,95%CI:1.096~7.329,P=0.001)和NLR(OR=3.842,95%CI:1.486~9.933,P=0.001)水平偏高为ACI静脉溶栓后短期内预后不佳的危险因素。结论存在糖尿病史、入院24 h NIHSS评分≥15分、血清BNP及NLR水平偏高的ACI静脉溶栓患者更易出现预后不佳的情况。
