Organized by Consiglio Nazional delle Ricerche (CNR), Gruppo Nedonale diIdraulice(GNI) with the support of the Ministry of Public Works and under the auspices of theCoastal Engineering Research Council(CERC) of the Am...Organized by Consiglio Nazional delle Ricerche (CNR), Gruppo Nedonale diIdraulice(GNI) with the support of the Ministry of Public Works and under the auspices of theCoastal Engineering Research Council(CERC) of the American Society of CivilEngineering(ASCE), and co-sponsored by the international Association for Hydraulic of Navi-gation Congress(PIANC) and by the Associazione di Ingegneria Offshore e Marina(AIOM).Aim展开更多
目的研究血清基质金属蛋白酶-9(MMP-9)、基质金属蛋白酶-26(MMP-26)、基质金属蛋白酶抑制剂-4(TIMP-4)与弥漫大B细胞淋巴瘤(Diffuse large B celllymphoma,DLBCL)病理分期及预后的相关性。方法选取2021年1月1日至2022年4月1日于上海交...目的研究血清基质金属蛋白酶-9(MMP-9)、基质金属蛋白酶-26(MMP-26)、基质金属蛋白酶抑制剂-4(TIMP-4)与弥漫大B细胞淋巴瘤(Diffuse large B celllymphoma,DLBCL)病理分期及预后的相关性。方法选取2021年1月1日至2022年4月1日于上海交通大学医学院附属瑞金医院治疗的75例DLBCL患者为研究组,另选取75例淋巴结反应性增生患者作为对照组,观察研究组与对照组及研究组不同分期、不同发病部位血清MMP-9、MMP-26及TIMP-4水平;采用Spearman分析DLBCL患者血清MMP-9、MMP-26与TIMP-4间的相关性;绘制Kaplan-Meier生存曲线,分析MMP-9、MMP-26、TIMP-4水平与DLBCL患者预后的关系。结果研究组血清MMP-9、MMP-26水平均高于对照组,血清TIMP-4水平均低于对照组,差异有统计学意义(P<0.05)。研究组Ⅰ~Ⅱ期患者血清MMP-9、MMP-26水平低于Ⅲ~Ⅳ期患者,血清TIMP-4水平高于Ⅲ~Ⅳ期患者,差异有统计学意义(P<0.05)。研究组不同发病部位患者血清MMP-9、MMP-26、TIMP-4水平比较差异均无统计学意义(P>0.05)。DLBCL患者血清MMP-9、MMP-26水平与TIMP-4水平呈负相关(P<0.05);血清MMP-9水平与MMP-26水平正相关(P<0.05)。MMP-9和MMP-26高表达、TIMP-4低表达组患者累积生存率低于其他组患者,差异具有统计学意义(P<0.05)。结论血清MMP-9、MMP-26及TIMP-4水平与DLBCL病理分期及患者预后密切相关,检测血清MMP-9、MMP-26及TIMP-4水平有助于明确DLBCL病理分期及评价患者预后。展开更多
Dyeing wastewater poses a serious threat to environmental protection and industrial development.The piezoelectric effect can be used to optimize the band structure of semiconductors and improve the photon efficiency o...Dyeing wastewater poses a serious threat to environmental protection and industrial development.The piezoelectric effect can be used to optimize the band structure of semiconductors and improve the photon efficiency of photocatalysts.Bi_(2)Fe_(4)O_(9),a narrow gap semiconductor with piezoelectric effect,was prepared by a hydrothermal synthesis method for the degradation of reactive dye KN-R.The results show that the degradation efficiency of KN-R can be significantly improved by piezo-photocatalysis,and the degradation rate constant of piezo-photocatalysis k_(pi-ph)is about 3.4 times as large as the degradation rate constant of piezoelectric catalysis k_(pi)and about 2.6 times as large as the degradation rate constant of photocatalysis k_(ph).At a pH value of 3 and a lower KN-R mass concentration(60 mg/L),a higher degradation efficiency(98.5%)is achieved.CO_(3)^(2-)and cationic surfactant(CTAB)inhibit the degradation of KN-R.It is proved that the contributions of different active species to the degradation of KN-R follow the order:·OH,·O_(2)^(-),h^(+),and^(1)O_(2).The possible mechanism of piezo-photocatalytic degradation of KN-R was discussed.The photoexcitation generates a large amount of free charges,and the piezoelectric effect modulates the energy band structure of Bi_(2)Fe_(4)O_(9)and promotes the separation of photogenerated electron-hole pairs.The synergistic effect of the two factors significantly improves the degradation efficiency of KN-R.展开更多
文摘Organized by Consiglio Nazional delle Ricerche (CNR), Gruppo Nedonale diIdraulice(GNI) with the support of the Ministry of Public Works and under the auspices of theCoastal Engineering Research Council(CERC) of the American Society of CivilEngineering(ASCE), and co-sponsored by the international Association for Hydraulic of Navi-gation Congress(PIANC) and by the Associazione di Ingegneria Offshore e Marina(AIOM).Aim
文摘目的研究血清基质金属蛋白酶-9(MMP-9)、基质金属蛋白酶-26(MMP-26)、基质金属蛋白酶抑制剂-4(TIMP-4)与弥漫大B细胞淋巴瘤(Diffuse large B celllymphoma,DLBCL)病理分期及预后的相关性。方法选取2021年1月1日至2022年4月1日于上海交通大学医学院附属瑞金医院治疗的75例DLBCL患者为研究组,另选取75例淋巴结反应性增生患者作为对照组,观察研究组与对照组及研究组不同分期、不同发病部位血清MMP-9、MMP-26及TIMP-4水平;采用Spearman分析DLBCL患者血清MMP-9、MMP-26与TIMP-4间的相关性;绘制Kaplan-Meier生存曲线,分析MMP-9、MMP-26、TIMP-4水平与DLBCL患者预后的关系。结果研究组血清MMP-9、MMP-26水平均高于对照组,血清TIMP-4水平均低于对照组,差异有统计学意义(P<0.05)。研究组Ⅰ~Ⅱ期患者血清MMP-9、MMP-26水平低于Ⅲ~Ⅳ期患者,血清TIMP-4水平高于Ⅲ~Ⅳ期患者,差异有统计学意义(P<0.05)。研究组不同发病部位患者血清MMP-9、MMP-26、TIMP-4水平比较差异均无统计学意义(P>0.05)。DLBCL患者血清MMP-9、MMP-26水平与TIMP-4水平呈负相关(P<0.05);血清MMP-9水平与MMP-26水平正相关(P<0.05)。MMP-9和MMP-26高表达、TIMP-4低表达组患者累积生存率低于其他组患者,差异具有统计学意义(P<0.05)。结论血清MMP-9、MMP-26及TIMP-4水平与DLBCL病理分期及患者预后密切相关,检测血清MMP-9、MMP-26及TIMP-4水平有助于明确DLBCL病理分期及评价患者预后。
文摘Dyeing wastewater poses a serious threat to environmental protection and industrial development.The piezoelectric effect can be used to optimize the band structure of semiconductors and improve the photon efficiency of photocatalysts.Bi_(2)Fe_(4)O_(9),a narrow gap semiconductor with piezoelectric effect,was prepared by a hydrothermal synthesis method for the degradation of reactive dye KN-R.The results show that the degradation efficiency of KN-R can be significantly improved by piezo-photocatalysis,and the degradation rate constant of piezo-photocatalysis k_(pi-ph)is about 3.4 times as large as the degradation rate constant of piezoelectric catalysis k_(pi)and about 2.6 times as large as the degradation rate constant of photocatalysis k_(ph).At a pH value of 3 and a lower KN-R mass concentration(60 mg/L),a higher degradation efficiency(98.5%)is achieved.CO_(3)^(2-)and cationic surfactant(CTAB)inhibit the degradation of KN-R.It is proved that the contributions of different active species to the degradation of KN-R follow the order:·OH,·O_(2)^(-),h^(+),and^(1)O_(2).The possible mechanism of piezo-photocatalytic degradation of KN-R was discussed.The photoexcitation generates a large amount of free charges,and the piezoelectric effect modulates the energy band structure of Bi_(2)Fe_(4)O_(9)and promotes the separation of photogenerated electron-hole pairs.The synergistic effect of the two factors significantly improves the degradation efficiency of KN-R.
