The use of commercial products such as a cup and liner for total hip arthroplasty for patients with severe bone defects has a high probability of failure.In these patients the cup alone cannot cover the bone defect,an...The use of commercial products such as a cup and liner for total hip arthroplasty for patients with severe bone defects has a high probability of failure.In these patients the cup alone cannot cover the bone defect,and thus,an additional augment or cage is required.In this study,we designed three-dimensional(3D)printable bone augments as an alternative to surgeries using reinforcement cages.Thirty-five sharp-edged bone augments of various sizes were 3D printed.A biporous structure was designed to reduce the weight of the augment and to facilitate bone ingrowth.Two types of frames were used to prevent damage to the augment’s porous structure and maintain its stability during printing.Furthermore,two types of holes were provided for easy augment fixation at various angles.Fatigue tests were performed on a combination of worst-case sizes derived using finite element analysis.The test results confirmed the structural stability of the specimens at a load of 5340 N.Although the porosity of the specimens was measured to be 63.70%,it cannot be said that the porous nature was uniformly distributed because porosity tests were performed locally and randomly.In summary,3D-printable biporous bone augments capable of bonding from various angles and bidirectionally through angulation and bottom-plane screw holes are proposed.The mechanical results with bone augments indicate good structural safety in patients.However,further research is necessary to study the clinical applications of the proposed bone augment.展开更多
Polyacrylic acid(PAA)hydrogel composites with different hexagonal boron nitride(h-BN)fillers were synthesized and successfully 3D-printed while their thermal conductivity was systematically studied.With the content of...Polyacrylic acid(PAA)hydrogel composites with different hexagonal boron nitride(h-BN)fillers were synthesized and successfully 3D-printed while their thermal conductivity was systematically studied.With the content of h-BN increasing from 0.1 wt%to 0.3 wt%,the thermal conductivity of the 3D-printed composites has been improved.Moreover,through the shear force given by the 3D printer,a complete thermal conductivity path is obtained inside the hydrogel,which significantly improves the thermal conductivity of the h-BN hydrogel composites.The maximum thermal conductivity is 0.8808 W/(m·K),leading to a thermal conductive enhancement of 1000%,compared with the thermal conductivity of pure PAA hydrogels.This study shows that using h-BN fillers can effectively and significantly improve the thermal conductivity of hydrogelbased materials while its 3D-printable ability has been maintained.展开更多
Animal fats usually contain high amounts of long-chain saturated fatty acids and cholesterol,and plant-based fat analogs have the potential to serve as substitutes for animal fats.However,most fat analog products coul...Animal fats usually contain high amounts of long-chain saturated fatty acids and cholesterol,and plant-based fat analogs have the potential to serve as substitutes for animal fats.However,most fat analog products could not mimic the oil-release behavior of animal fats.Therefore,this study developed 3D-printable emulsified fat analogs utilizing konjac glucomannan and coconut oil and adjusted the oil stability of the fat analog system before and after cooking.Before cooking,the fat analogs showed excellent printing behavior with a homogenous state and no oil release.The raw inks hold intermediate rheological properties so that the printed fat analogs showed acceptable shape stability and surface smoothness during printing.After cooking,the fat analogs experienced significant oil release.In addition,the influences of oil content on the glucomannan-based emulsion gels’oil release behavior,and rheological and textural properties were investigated.The results showed that the fat analogs with a higher coconut oil content showed a larger amount of released oil,higher oil loss,water loss,and cooking loss,and lower hardness and tensile strength after cooking.The temperature sweep test showed that the glucomannan-based fat analogs formed gels during heating.This study offers a method to develop emulsion plant-based fat analogs with high oil-release and stretchable properties after cooking.展开更多
基金supported by the Technology Development Program(P0011350)funded by the Ministry of SMEs and Startups(MSS,Korea)。
文摘The use of commercial products such as a cup and liner for total hip arthroplasty for patients with severe bone defects has a high probability of failure.In these patients the cup alone cannot cover the bone defect,and thus,an additional augment or cage is required.In this study,we designed three-dimensional(3D)printable bone augments as an alternative to surgeries using reinforcement cages.Thirty-five sharp-edged bone augments of various sizes were 3D printed.A biporous structure was designed to reduce the weight of the augment and to facilitate bone ingrowth.Two types of frames were used to prevent damage to the augment’s porous structure and maintain its stability during printing.Furthermore,two types of holes were provided for easy augment fixation at various angles.Fatigue tests were performed on a combination of worst-case sizes derived using finite element analysis.The test results confirmed the structural stability of the specimens at a load of 5340 N.Although the porosity of the specimens was measured to be 63.70%,it cannot be said that the porous nature was uniformly distributed because porosity tests were performed locally and randomly.In summary,3D-printable biporous bone augments capable of bonding from various angles and bidirectionally through angulation and bottom-plane screw holes are proposed.The mechanical results with bone augments indicate good structural safety in patients.However,further research is necessary to study the clinical applications of the proposed bone augment.
基金Funed by the National Key Research and Development Program of China(No.2021YFA0715700)the Open Fund of Hubei Longzhong Laboratory。
文摘Polyacrylic acid(PAA)hydrogel composites with different hexagonal boron nitride(h-BN)fillers were synthesized and successfully 3D-printed while their thermal conductivity was systematically studied.With the content of h-BN increasing from 0.1 wt%to 0.3 wt%,the thermal conductivity of the 3D-printed composites has been improved.Moreover,through the shear force given by the 3D printer,a complete thermal conductivity path is obtained inside the hydrogel,which significantly improves the thermal conductivity of the h-BN hydrogel composites.The maximum thermal conductivity is 0.8808 W/(m·K),leading to a thermal conductive enhancement of 1000%,compared with the thermal conductivity of pure PAA hydrogels.This study shows that using h-BN fillers can effectively and significantly improve the thermal conductivity of hydrogelbased materials while its 3D-printable ability has been maintained.
基金supported by the Basic Science Research Program through the National Research Foundation of Korea(NRF)funded by the Ministry of Science,ICT&Future Planning[grant number NRF-2020R1A2C1011723]collaborative research program between the university and Rural Development Administration[PJ01527503,PJ01591202]+2 种基金Republic of Koreathe Institute of Biomedical Science&Food Safety,Korea Universityand China Scholarship Council.
文摘Animal fats usually contain high amounts of long-chain saturated fatty acids and cholesterol,and plant-based fat analogs have the potential to serve as substitutes for animal fats.However,most fat analog products could not mimic the oil-release behavior of animal fats.Therefore,this study developed 3D-printable emulsified fat analogs utilizing konjac glucomannan and coconut oil and adjusted the oil stability of the fat analog system before and after cooking.Before cooking,the fat analogs showed excellent printing behavior with a homogenous state and no oil release.The raw inks hold intermediate rheological properties so that the printed fat analogs showed acceptable shape stability and surface smoothness during printing.After cooking,the fat analogs experienced significant oil release.In addition,the influences of oil content on the glucomannan-based emulsion gels’oil release behavior,and rheological and textural properties were investigated.The results showed that the fat analogs with a higher coconut oil content showed a larger amount of released oil,higher oil loss,water loss,and cooking loss,and lower hardness and tensile strength after cooking.The temperature sweep test showed that the glucomannan-based fat analogs formed gels during heating.This study offers a method to develop emulsion plant-based fat analogs with high oil-release and stretchable properties after cooking.
