5-Fluorouracil salt(WBF) of 12-tungstoboric acid with Keggin structure was synthesized and its structure was characterized by IR, 1H NMR, 183 W NMR and elementary analysis. The MTT experimental results show that WBF h...5-Fluorouracil salt(WBF) of 12-tungstoboric acid with Keggin structure was synthesized and its structure was characterized by IR, 1H NMR, 183 W NMR and elementary analysis. The MTT experimental results show that WBF has a stronger killing ability for liver cancer cells in vitro. The acute toxicity of WBF was carried out. The half toxicity dose LD_ 50 of WBF orally administrated to mice is 1 117.4 mg/kg. [WT5HZ]展开更多
文摘5-Fluorouracil salt(WBF) of 12-tungstoboric acid with Keggin structure was synthesized and its structure was characterized by IR, 1H NMR, 183 W NMR and elementary analysis. The MTT experimental results show that WBF has a stronger killing ability for liver cancer cells in vitro. The acute toxicity of WBF was carried out. The half toxicity dose LD_ 50 of WBF orally administrated to mice is 1 117.4 mg/kg. [WT5HZ]
