The pulse shape discrimination technique plays a pivotal role in neutron field measurements using organic scintillator detectors,and the particle-type labeling accuracy of the pulse waveform dataset has a significant ...The pulse shape discrimination technique plays a pivotal role in neutron field measurements using organic scintillator detectors,and the particle-type labeling accuracy of the pulse waveform dataset has a significant impact on its performance,especially with the growing use of machine learning methods.In this study,a high-accuracy labeling method for pulse waveform datasets based on the time-of-flight(TOF)filtering method,an improved charge comparison method(CCM),and the coincidence measurement method is proposed.The relationship between the experimental parameters and the chance coincidence proportion in the TOF measurement was derived to reduce contamination from chance coincidences at the experimental level.Based on this,an experiment was conducted to obtain raw data using the^(241)AmBe source,and a piled-up identification algorithm based on reference waveform cross-correlation and differential analysis was designed to filter out piled-up pulses.To improve the labeling accuracy,the CCM was optimized,a simple method of selecting the TOF interval for a lower chance coincidence proportion was proposed,and a low-amplitude pulse waveform dataset construction method based on coincidence measurements was developed.To verify these methods,eight pulse waveform datasets were constructed using different combinations of the proposed approaches.Three neural network structures and a corresponding evaluation parameter were designed to test the quality of these datasets.The results showed that the particle identification performance of the CCM was significantly improved after optimization,with the neutron-to-gamma-ray misidentification rate reduced by more than 35%.The proposed accuracy improvement methods reduced ambiguous identification results from these artificial neural networks by more than 50%.展开更多
Due to the numerous variables to take into account as well as the inherent ambiguity and uncertainty,evaluating educational institutions can be difficult.The concept of a possibility Pythagorean fuzzy hypersoft set(pP...Due to the numerous variables to take into account as well as the inherent ambiguity and uncertainty,evaluating educational institutions can be difficult.The concept of a possibility Pythagorean fuzzy hypersoft set(pPyFHSS)is more flexible in this regard than other theoretical fuzzy set-like models,even though some attempts have been made in the literature to address such uncertainties.This study investigates the elementary notions of pPyFHSS including its set-theoretic operations union,intersection,complement,OR-and AND-operations.Some results related to these operations are also modified for pPyFHSS.Additionally,the similarity measures between pPyFHSSs are formulated with the assistance of numerical examples and results.Lastly,an intelligent decision-assisted mechanism is developed with the proposal of a robust algorithm based on similarity measures for solving multi-attribute decision-making(MADM)problems.A case study that helps the decision-makers assess the best educational institution is discussed to validate the suggested system.The algorithmic results are compared with the most pertinent model to evaluate the adaptability of pPyFHSS,as it generalizes the classical possibility fuzzy set-like theoretical models.Similarly,while considering significant evaluating factors,the flexibility of pPyFHSS is observed through structural comparison.展开更多
Dear Editor,This letter deals with the distributed recursive set-membership filtering(DRSMF)issue for state-saturated systems under encryption-decryption mechanism.To guarantee the data security,the encryption-decrypt...Dear Editor,This letter deals with the distributed recursive set-membership filtering(DRSMF)issue for state-saturated systems under encryption-decryption mechanism.To guarantee the data security,the encryption-decryption mechanism is considered in the signal transmission process.Specifically,a novel DRSMF scheme is developed such that,for both state saturation and encryption-decryption mechanism,the filtering error(FE)is limited to the ellipsoid domain.Then,the filtering error constraint matrix(FECM)is computed and a desirable filter gain is derived by minimizing the FECM.Besides,the bound-edness evaluation of the FECM is provided.展开更多
A cylindrical chamber with a rotating bottom holds significant potential for application in cell culture bioreactors due to its ability to generate more stable swirling flows.In order to control vortex breakdown withi...A cylindrical chamber with a rotating bottom holds significant potential for application in cell culture bioreactors due to its ability to generate more stable swirling flows.In order to control vortex breakdown within the chamber,this study first establishes a computational fluid dynamics simulation coupled with the level set method.Verified by experimental results in literature,this method accurately simulates the position and shape of vortex breakdown,and also predicts the critical Reynolds numbers for the appearance and detachment of vortex breakdown bubbles from the center.Additionally,it precisely captures the gas-liquid interface and depicts the vortex breakdown phenomenon in the air above the liquid for the first time.Finally,it predicts the impact of physical property of gas-liquid systems on vortex breakdown in response to significant changes in viscosity of microbial process systems.展开更多
The existing panoramic image matching methods are difficult to overcome the non-uniform features of the projection transformation of the target object,and hence the issue of unstable corresponding points matching is u...The existing panoramic image matching methods are difficult to overcome the non-uniform features of the projection transformation of the target object,and hence the issue of unstable corresponding points matching is usually induced.This paper aims to solve the difficulty by proposing a sparse depth point set matching method based on panoramic disparity.By constructing a panoramic disparity model of stereo panoramic images,the disparity between corresponding points can be precisely estimated,and the robustness and effectiveness of corresponding points matching between stereo panoramic images is improved under the epipolar geometric constraints.Firstly,by defining the panoramic disparity,the corresponding angle of panoramic disparity is derived,and the matching areas of corresponding points based on the disparity corresponding angle difference are partitioned.Secondly,the optimization strategy in the matching process of corresponding points is constructed to provide stable matching results for generating sparse depth maps based on the disparity region range and epipolar geometric relationship.Experiments show that the proposed method can not only obtain more stable matching results but also exhibit higher computational efficiency than existing algorithms.展开更多
Nonlocal set of orthogonal product states(OPSs)can improve the confidentiality of information when it is used to design quantum cryptographic protocols.It is a difficult question how to construct a nonlocal set of OPS...Nonlocal set of orthogonal product states(OPSs)can improve the confidentiality of information when it is used to design quantum cryptographic protocols.It is a difficult question how to construct a nonlocal set of OPSs on general multipartite and high dimensional quantum systems.Different from the previous works,we first present a novel method for constructing a nonlocal product set with 3d-2 members on C^(d)■C^(d)■C^(d)quantum system for d≥3.Then,we extend this construction method to C^(d_(1))■C^(d_(2))■C^(d_(3))quantum system and■_(i=1)^(n)C^(di)quantum system respectively,where 3≤d_(1)≤d_(2)≤d_(3)≤…≤dC_(d_(i))and n≥3.The nonlocal set of OPSs constructed by our method contains fewer elements than those constructed by the existing methods,except for one special case.More importantly,the set of states constructed by our method has a completely different structure from those constructed by the existing methods since our nonlocal set does not contain a“stopper”state.Our result is helpful to further understand the different structures of nonlocal sets on multipartite systems.展开更多
Local strong seismic activity shows the potential to closely follow a renewal process,which is inconsistent with the overall seismic activity that aligns with the Poisson process.Given that existing methods for synthe...Local strong seismic activity shows the potential to closely follow a renewal process,which is inconsistent with the overall seismic activity that aligns with the Poisson process.Given that existing methods for synthesizing stochastic seismic event sets cannot control local seismic activity,a method based on Monte Carlo simulations has been developed for synthesizing random seismic event sets where local strong earthquakes satisfy the renewal process.This method can synthesize seismic activities in a statistical area where the overall activity conforms to the Poisson process and the major seismic activities in local potential sources or faults follow the renewal process.This paper presents long-and short-scale approaches.The long-scale earthquake catalogs are suitable for reflecting the sequential characteristics of seismic activities.Meanwhile,the short-scale catalogs focus on the impacts of specific earthquake events within a group for a detailed understanding of hazards under certain conditions,making them suitable for studies on specific earthquake sequences and geological areas or situations requiring high temporal resolution.In the applications of shortscale sequences,we find that the equivalent occurrence rate method may overestimate the seismic hazard.This synthesis method for earthquake catalogs can simulate realistic seismic activities,thereby enhancing the accuracy of hazard analysis results and is suitable for seismic hazard analysis and earthquake insurance rate setting.展开更多
Parameterized level-set method(PLSM)has been proposed and developed for many years,and is renowned for its efficacy in ad-dressing topology optimization challenges associated with intricate boundaries and nucleation o...Parameterized level-set method(PLSM)has been proposed and developed for many years,and is renowned for its efficacy in ad-dressing topology optimization challenges associated with intricate boundaries and nucleation of new holes.However,most pertinent investigations in the field rely predominantly on fixed background mesh,which is never remeshed.Consequently,the mesh element partitioned by material interface during the optimization process necessitates approximation by using artificial interpolation models to obtain its element stiffness or other properties.This paper introduces a novel approach to topology op-timization by integrating the PLSM with body-fitted adaptive mesh and Helmholtz-type filter.Primarily,combining the PLSM with body-fitted adaptive mesh enables the regeneration of mesh based on the zero level-set interface.This not only precludes the direct traversal of the material interface through the mesh element during the topology optimization process,but also improves the accuracy of calculation.Additionally,the incorporation of a Helmholtz-type partial differential equation filter,relying solely on mesh information essential for finite element discretization,serves to regulate the topological complexity and the minimum feature size of the optimized structure.Leveraging these advantages,the topology optimization program demonstrates its versa-tility by successfully addressing various design problems,encompassing the minimum mean compliance problem and minimum energy dissipation problem.Ultimately,the result of numerical example indicates that the optimized structure exhibits a dis-tinct and smooth boundary,affirming the effective control over both topological complexity and the minimum feature size of the optimized structure.展开更多
This study systematically conducted preparation optimization and performance investigations on Co-modified Ce/TiO_(2) catalysts,with a focus on examining how preparation methods and Co loading regulate the catalyst’s...This study systematically conducted preparation optimization and performance investigations on Co-modified Ce/TiO_(2) catalysts,with a focus on examining how preparation methods and Co loading regulate the catalyst’s low-temperature denitrification activity.After identifying optimal preparation parameters via condition screening,multiple characterization techniques-including BET,XRD,XPS,H_(2)-TPR and in situ DRIFTS-were employed to deeply analyze the catalyst’s physicochemical properties and reaction mechanism.Results demonstrated that compared to the impregnation and co-precipitation methods,the Ce-Co_(0.025)/TiO_(2)-SG catalyst(prepared by the sol-gel method with a Co/Ti mass ratio of 0.025)exhibited significantly superior denitrification activity:NO conversion remained stably above 95%in the 225−350℃ temperature range,and it displayed high N_(2) selectivity.Characterization analysis revealed that abundant surface oxygen vacancies,a high proportion of Ce^(3+) species,and prominent acidic sites collectively contributed to enhancing its low-temperature denitrification performance.This work provides reference value for the development of highly efficient low-temperature denitrification catalysts.展开更多
In this paper,we consider the maximal positive definite solution of the nonlinear matrix equation.By using the idea of Algorithm 2.1 in ZHANG(2013),a new inversion-free method with a stepsize parameter is proposed to ...In this paper,we consider the maximal positive definite solution of the nonlinear matrix equation.By using the idea of Algorithm 2.1 in ZHANG(2013),a new inversion-free method with a stepsize parameter is proposed to obtain the maximal positive definite solution of nonlinear matrix equation X+A^(*)X|^(-α)A=Q with the case 0<α≤1.Based on this method,a new iterative algorithm is developed,and its convergence proof is given.Finally,two numerical examples are provided to show the effectiveness of the proposed method.展开更多
This study investigates the influence of the elastic modulus(E)of the composite strata on the trough width coefficient(i).It is hypothesized that,in composite strata,the relationship between the trough width coefficie...This study investigates the influence of the elastic modulus(E)of the composite strata on the trough width coefficient(i).It is hypothesized that,in composite strata,the relationship between the trough width coefficient(i)and the stratum thickness(H)follows a piecewise linear trend.Specifically,within strata of identical elastic modulus(E),i exhibits a linear correlation with H,while variations in E affect the slope of this correlation.Building upon the non-iterative analytical method(NIAM)for evaluating tunnel excavation responses in composite strata,this study proposes two novel approaches:the crucial point method(CPM)and the standard curve method(SCM).These methods incorporate the elastic modulus into the estimation of i.The values of i obtained via NIAM and refined through CPM and SCM are validated against field data using the parameter K.The results are consistent with existing research findings,thereby confirming the reliability of the proposed methodology.Furthermore,the study investigates the relationship between tunnel depth(h0)and tunnel radius(R),and explores the interactions among the layer number of stratum(n),elastic modulus(E),and layer thickness(H).A reduction coefficient(η)is introduced to improve the model's accuracy.The proposed approach is applied to nine tunnel engineering cases,and comparisons with measured data demonstrate its accuracy and practical applicability.展开更多
This study presents an effective hybrid simulation approach for simulating broadband ground motion in complex near-fault locations.The approach utilizes a deterministic approach based on the spectral element method(SE...This study presents an effective hybrid simulation approach for simulating broadband ground motion in complex near-fault locations.The approach utilizes a deterministic approach based on the spectral element method(SEM),which is used to simulate low-frequency ground motion(f<1 Hz)by incorporating an innovative efficient discontinuous Galerkin(DG)method for grid division to accurately model basin sedimentary layers at reduced costs.It also introduces a comprehensive hybrid source model for high-frequency random scattering and a nonlinear analysis module for basin sedimentary layers.Deterministic outcomes are combined with modified three-dimensional stochastic finite fault method(3D-EXSIM)simulations of high-frequency ground motion(f>1 Hz).A fourth-order Butterworth filter with zero phase shift is employed for time-domain filtering of low-and high-frequency time series at a crossover frequency of 1 Hz,merging the low and high-frequency ground motions into a broadband time series.Taking an Ms 6.8 Luding earthquake,as an example,this hybrid method was used for a rapid and efficient simulation analysis of broadband ground motion in the region.The accuracy and efficiency of this hybrid method were verified through comparisons with actually observed station data and empirical attenuation curves.Deterministic method simulation results revealed the effects of mountainous topography,basin effects,nonlinear effects within the basin’s sedimentary layers,and a coupling interaction between the basin and the mountains.The findings are consistent with similar studies,showing that near-fault sedimentary basins significantly focus and amplify strong ground motion,and the soil’s nonlinear behavior in the basin influences ground motion to varying extents at different distances from the fault.The mountainous topography impacts the basin’s response to ground motion,leading to barrier effects.This research provides a scientific foundation for seismic zoning,urban planning,and seismic design in nearfault mountain basin regions.展开更多
Circumlunar abort trajectories constitute a vital contingency return strategy during the translunar phase of crewed lunar missions.This paper proposes a methodology for constructing the solution set of the circumlunar...Circumlunar abort trajectories constitute a vital contingency return strategy during the translunar phase of crewed lunar missions.This paper proposes a methodology for constructing the solution set of the circumlunar abort trajectory and leverages its advantageous properties to address the optimization design problem of abort trajectories.Initially,a solution set of all feasible abort trajectories,originating from an abort point on the nominal trajectory and complying with fundamental reentry constraints,is formulated through the introduction of two novel design parameters.Subsequently,the geometric characteristics of the solution set,as well as the distributional properties of key iterative constraint responses,including flight time and velocity increment,are analyzed.Finally,the characteristics exhibited in the solution set are employed to directly identify the design parameters of the abort trajectories with minimum flight time and velocity increment,thereby providing solutions to two distinct types of optimization problems.The simulation results for a variety of nominal trajectories,encompassing the reconstruction and redesign of the Apollo13 abort trajectory,validate the proposed method,demonstrating its ability to directly generate optimal abort trajectories.The method proposed in this paper investigates feasible abort trajectories from a global perspective,providing both a framework and convenience for mission planning and iterative optimization in abort trajectory design.展开更多
[Objectives]This study was conducted to establish a quantitative assessment method for the textural quality of chieh-qua fruit.[Methods]Using two modes of a texture analyzer,namely TPA(texture profile analysis)and pun...[Objectives]This study was conducted to establish a quantitative assessment method for the textural quality of chieh-qua fruit.[Methods]Using two modes of a texture analyzer,namely TPA(texture profile analysis)and puncture,the index data of the fruit were obtained by setting different trigger forces,deformation levels,test speeds,as well as puncture speeds and puncture depths.The data included TPA hardness,adhesiveness,springiness,cohesiveness,gumminess,chewiness,resilience,as well as skin hardness,skin toughness,flesh hardness,fracturability,and compactness.[Results]Different deformation levels had a significant impact on all parameters.Hardness,adhesiveness,gumminess and chewiness showed a trend of first increasing and then decreasing with the deformation level increasing.When the deformation level was 30%,the adhesiveness,gumminess and chewiness reached their maximum values.When the deformation level was 50%,TPA hardness reached its maximum.When the compression speed was 3 mm/s,the measured values of TPA hardness,adhesiveness,chewiness,and resilience were at their maximums.The skin hardness varied significantly under different trigger forces.When the trigger force was 15 g,the skin hardness reached a maximum value of 944.63 g,and the skin toughness,flesh hardness,fracturability,and compactness also reach their maximum values respectively.When the puncture depth was 12 mm,the flesh hardness and skin toughness reached their maximums of 682.51 g and 1.82 mm,respectively.In the TPA mode,the flesh hardness of chieh-qua showed an extremely significant negative correlation with springiness,cohesiveness,and resilience(P<0.01).The fruit fracturability detected by puncture had an extremely significant positive correlation with compactness(P<0.01).[Conclusions]The evaluation method for measuring chieh-qua texture by combining TPA and the puncture mode could accurately and quantitatively reflect the differences in the flesh texture quality of chieh-qua.The optimal parameters for texture measurement of chieh-qua fruit were determined as a 15 g trigger force with 50%deformation and a 3 mm/s compression speed in TPA mode,and a 15 g trigger force with a 12 mm puncture depth in puncture mode.Puncture speed was found to have no significant effect on the texture indices of chieh-qua.展开更多
The testing of large structures is limited by high costs and long cycles, making scaling methods an attractive solution. However, the scaling process of elastic rings introduces complexities in multi-parameter geometr...The testing of large structures is limited by high costs and long cycles, making scaling methods an attractive solution. However, the scaling process of elastic rings introduces complexities in multi-parameter geometric distortions, leading to a diminution in the predictive accuracy of the distorted similitude. To address this challenge, this study formulates a novel set of scaling laws, tailored to account for the intricate geometric distortions associated with elastic rings. The proposed scaling laws are formulated based on the intrinsic deformation characteristics of elastic rings, rather than the traditional systemic governing equations. Numerical and experimental cases are conducted to assess the efficacy and precision of the proposed scaling laws, and the obtained results are compared with those achieved by traditional methods. The outcomes demonstrate that the scaling laws put forth by this study significantly enhance the predictive capabilities for deformations of elastic rings.展开更多
In this study,we perform particle-resolved simulations of settling spheroidal particles,considering oblate and prolate spheroids and spheres,and investigate the shape effect on the particle dynamics in suspensions wit...In this study,we perform particle-resolved simulations of settling spheroidal particles,considering oblate and prolate spheroids and spheres,and investigate the shape effect on the particle dynamics in suspensions with volume fraction 1%and 5%.We first examine the single-point statistics of the translational and rotational motion of the settling particles.The horizontal velocity has a symmetrical distribution with standard deviation dependent on the particle shape.The greater horizontal velocity fluctuations of the non-spherical particles,compared to that of spheres,are attributed to the horizontal drift of settling spheroids with oblique orientations induced by the fluid-particle and particle-particle interactions.The fluctuation of particle vertical velocity,instead,is skewed under the effect of wake-induced hydrodynamic interactions.Further,we explore the particle pair statistics,which demonstrate the formation of column-like particle micro-structures for the lowest volume fraction considered.This clustering is more pronounced for spheroidal particles than spheres,due to the stronger attractions among vertically-aligned settling spheroids.Moreover,the particle pair statistics are directly related to the collision rate among the dispersed particles.The local accumulation of oblate/prolate spheroids serves as the major mechanism to promote the particle-particle collisions in dilute suspensions.展开更多
This study presents an implicit multiphysics coupling method integrating Computational Fluid Dynamics(CFD),the Multiphase Particle-in-Cell(MPPIC)model,and the Finite Element Method(FEM),implemented with OpenFOAM,Calcu...This study presents an implicit multiphysics coupling method integrating Computational Fluid Dynamics(CFD),the Multiphase Particle-in-Cell(MPPIC)model,and the Finite Element Method(FEM),implemented with OpenFOAM,CalculiX,and preCICE to simulate fluid-particle-structure interactions with large deformations.Mesh motion in the fluid field is handled using the radial basis function(RBF)method.The particle phase is modeled by MPPIC,where fluid-particle interaction is described through momentum exchange,and inter-particle collisions are characterized by collision stress.The structural field is solved by nonlinear FEM to capture large deformations induced by geometric nonlinearity.Coupling among fields is realized through a partitioned,parallel,and non-intrusive iterative strategy,ensuring stable transfer and convergence of interface forces and displacements.Notably,the influence of particles on the structure is not direct but mediated by the fluid,while structural motion directly affects particle dynamics.The results demonstrate that the proposed approach effectively captures multiphysics interaction processes and provides a valuable reference for numerical modeling of coupled fluid-particle-structure systems.展开更多
Objectives:Tamoxifen is a key drug that provides endocrine therapy for estrogen receptor(ER)α-positive breast cancer;however,resistance remains a significant clinical challenge.This study aims to investigate the mole...Objectives:Tamoxifen is a key drug that provides endocrine therapy for estrogen receptor(ER)α-positive breast cancer;however,resistance remains a significant clinical challenge.This study aims to investigate the molecular mechanisms of tamoxifen resistance in ERα-positive breast cancer,with particular focus on the role of SET Domain Containing 1A(SETD1A)-driven forkhead box A2(FOXA2)as a key regulator of this resistance.Methods:FOXA2 expression and its regulation by SETD1A were assessed via(quantitative polymerase chain reaction),western blotting,transcriptome profiling,and chromatin immunoprecipitation analyses.The effects of FOXA2 on cell proliferation,migration,invasion,and cancer stem cell traits were evaluated using small interfering RNA(siRNA)-mediated silencing.Clinical relevance was examined by analyzing patient datasets and tumor tissue microarrays.Results:FOXA2 expression was significantly elevated in tamoxifen-resistant(TamR)and ERα-negative breast cancer cells compared to that in ERα-positive MCF-7 cells,regardless of tamoxifen treatment or ERαdepletion.Transcriptome and chromatin immunoprecipitation analyses revealed that SETD1A,a histone methyltransferase,directly regulated FOXA2 expression.Functionally,FOXA2 knockdown inhibited the proliferation,migration,invasion,and cancer stem cell properties of TamR cells while restoring tamoxifen sensitivity.High FOXA2 expression was correlated with poor survival and reduced responsiveness to tamoxifen in patients with ER-positive breast cancer.Conclusion:Our findings identified FOXA2 as a key mediator of tamoxifen resistance regulated by SETD1A and suggested that targeting the SETD1A-FOXA2 axis may offer a novel strategy for overcoming endocrine resistance in breast cancer.展开更多
Objectives This review aimed to systematically synthesize the available research on the disclosure of diagnosis and related issues in childhood cancer from the perspectives of healthcare professionals,with the goal of...Objectives This review aimed to systematically synthesize the available research on the disclosure of diagnosis and related issues in childhood cancer from the perspectives of healthcare professionals,with the goal of informing the optimization of disclosure processes and meeting the communication needs of affected families.Methods In accordance with the Joanna Briggs Institute(JBI)methodology for mixed methods systematic reviews,the convergent segregated approach was used in this review.Articles were retrieved from 11 databases,including PubMed,Web of Science,CINAHL,CENTRAL,Embase,Ovid/Medline,PsycINFO,PsycArticles,Scopus,ERIC,and China National Knowledge Infrastructure(CNKI).The quality of the selected articles was assessed using the Mixed Method Appraisal Tool(MMAT).The review protocol was registered on PROSPERO(CRD42024542746).Results A total of 21 studies from 10 countries were included.Their methodological quality was generally medium to high,with MMAT scores ranging from 60%to 100%.The synthesis yielded three core themes:1)the spectrum of professional and societal attitudes toward disclosure;2)the dynamic practices of navigating disclosure amid uncertainty,including timing and environment,stakeholders,and content of disclosure;and 3)factors influencing disclosure,including children’s,parental,healthcare professionals’,and socio-cultural factors.Conclusions This review synthesized the perspectives and experiences of healthcare professionals regarding disclosure in childhood cancer,highlighting the complexity and multidimensional nature of this process in clinical practice.Future research should further investigate the experiences and needs of children and their parents,explore cultural variations in disclosure practices,develop context-appropriate assessment tools,and construct multidimensional intervention strategies to enhance the humanistic care and professional effectiveness of the disclosure process.展开更多
As binary geological media,soil-rock mixtures(SRMs)exhibit a distinct gradational composition,leading to their unique mechanical behaviors.To appraise the stability of SRM slopes,it is essential to determine equivalen...As binary geological media,soil-rock mixtures(SRMs)exhibit a distinct gradational composition,leading to their unique mechanical behaviors.To appraise the stability of SRM slopes,it is essential to determine equivalent parameters of SRMs,which are typically obtained through experimental and numerical methods.In contrasted to other numerical methods,the numerical manifold method(NMM)is more effective in addressing SRM problems.This is because the high-precision regular mathematical meshes in NMM can be used without aligning with the soil-rock interfaces and boundaries of SRMs.In the current research,the equivalent strength parameters of SRMs,i.e.the equivalent cohesion ce and internal friction angleϕ_(e),are determined using NMM.Initially,an NMM triaxial numerical model is established and validated based on triaxial experiments.Subsequently,the soil and rock parameters are derived through parameter inversion.Moreover,the impacts of rock content,size,shape and rock blocks'major-axis orientation on ce andϕ_(e) of SRMs are thoroughly examined using the NMM triaxial numerical model.Additionally,a fitting function is proposed to linkϕ_(e) to the rock content and size of SRMs.When other influencing factors are fixed,the above fitting model leads to the following conclusions:(1)the predictedϕ_(e) of SRMs increase with the increase of rock content;and(2)SRM samples with smaller rocks display a higher predictedϕ_(e).展开更多
基金supported by the National Natural Science Foundation of China(Nos.12375297 and 12105144).
文摘The pulse shape discrimination technique plays a pivotal role in neutron field measurements using organic scintillator detectors,and the particle-type labeling accuracy of the pulse waveform dataset has a significant impact on its performance,especially with the growing use of machine learning methods.In this study,a high-accuracy labeling method for pulse waveform datasets based on the time-of-flight(TOF)filtering method,an improved charge comparison method(CCM),and the coincidence measurement method is proposed.The relationship between the experimental parameters and the chance coincidence proportion in the TOF measurement was derived to reduce contamination from chance coincidences at the experimental level.Based on this,an experiment was conducted to obtain raw data using the^(241)AmBe source,and a piled-up identification algorithm based on reference waveform cross-correlation and differential analysis was designed to filter out piled-up pulses.To improve the labeling accuracy,the CCM was optimized,a simple method of selecting the TOF interval for a lower chance coincidence proportion was proposed,and a low-amplitude pulse waveform dataset construction method based on coincidence measurements was developed.To verify these methods,eight pulse waveform datasets were constructed using different combinations of the proposed approaches.Three neural network structures and a corresponding evaluation parameter were designed to test the quality of these datasets.The results showed that the particle identification performance of the CCM was significantly improved after optimization,with the neutron-to-gamma-ray misidentification rate reduced by more than 35%.The proposed accuracy improvement methods reduced ambiguous identification results from these artificial neural networks by more than 50%.
基金supported by the Deanship of Graduate Studies and Scientific Research at Qassim University(QU-APC-2024-9/1).
文摘Due to the numerous variables to take into account as well as the inherent ambiguity and uncertainty,evaluating educational institutions can be difficult.The concept of a possibility Pythagorean fuzzy hypersoft set(pPyFHSS)is more flexible in this regard than other theoretical fuzzy set-like models,even though some attempts have been made in the literature to address such uncertainties.This study investigates the elementary notions of pPyFHSS including its set-theoretic operations union,intersection,complement,OR-and AND-operations.Some results related to these operations are also modified for pPyFHSS.Additionally,the similarity measures between pPyFHSSs are formulated with the assistance of numerical examples and results.Lastly,an intelligent decision-assisted mechanism is developed with the proposal of a robust algorithm based on similarity measures for solving multi-attribute decision-making(MADM)problems.A case study that helps the decision-makers assess the best educational institution is discussed to validate the suggested system.The algorithmic results are compared with the most pertinent model to evaluate the adaptability of pPyFHSS,as it generalizes the classical possibility fuzzy set-like theoretical models.Similarly,while considering significant evaluating factors,the flexibility of pPyFHSS is observed through structural comparison.
基金supported by the National Natural Science Foundation of China(12471416,12171124,12301567)the Heilongjiang Provincial Natural Science Foundation of China(PL2024F015)+2 种基金the Postdoctoral Science Foundation of Heilongjiang Province of China(LBH-Z22199)the Fundamental Research Foun-dation for Universities of Heilongjiang Province of China(2022-KYYWF-0141)the Alexander von Humboldt Foundation of Germany.
文摘Dear Editor,This letter deals with the distributed recursive set-membership filtering(DRSMF)issue for state-saturated systems under encryption-decryption mechanism.To guarantee the data security,the encryption-decryption mechanism is considered in the signal transmission process.Specifically,a novel DRSMF scheme is developed such that,for both state saturation and encryption-decryption mechanism,the filtering error(FE)is limited to the ellipsoid domain.Then,the filtering error constraint matrix(FECM)is computed and a desirable filter gain is derived by minimizing the FECM.Besides,the bound-edness evaluation of the FECM is provided.
基金National Natural Science Foundation of China(22178228,22178326)
文摘A cylindrical chamber with a rotating bottom holds significant potential for application in cell culture bioreactors due to its ability to generate more stable swirling flows.In order to control vortex breakdown within the chamber,this study first establishes a computational fluid dynamics simulation coupled with the level set method.Verified by experimental results in literature,this method accurately simulates the position and shape of vortex breakdown,and also predicts the critical Reynolds numbers for the appearance and detachment of vortex breakdown bubbles from the center.Additionally,it precisely captures the gas-liquid interface and depicts the vortex breakdown phenomenon in the air above the liquid for the first time.Finally,it predicts the impact of physical property of gas-liquid systems on vortex breakdown in response to significant changes in viscosity of microbial process systems.
基金National Natural Science Foundation of China(No.41761079)Top Young Talent Project of Yunnan Province in China.
文摘The existing panoramic image matching methods are difficult to overcome the non-uniform features of the projection transformation of the target object,and hence the issue of unstable corresponding points matching is usually induced.This paper aims to solve the difficulty by proposing a sparse depth point set matching method based on panoramic disparity.By constructing a panoramic disparity model of stereo panoramic images,the disparity between corresponding points can be precisely estimated,and the robustness and effectiveness of corresponding points matching between stereo panoramic images is improved under the epipolar geometric constraints.Firstly,by defining the panoramic disparity,the corresponding angle of panoramic disparity is derived,and the matching areas of corresponding points based on the disparity corresponding angle difference are partitioned.Secondly,the optimization strategy in the matching process of corresponding points is constructed to provide stable matching results for generating sparse depth maps based on the disparity region range and epipolar geometric relationship.Experiments show that the proposed method can not only obtain more stable matching results but also exhibit higher computational efficiency than existing algorithms.
基金supported by the National Natural Science Foundation of China(Grant No.62171264)the Natural Science Foundation of Shandong Province of China(Grant No.ZR2023MF080)the Natural Science Foundation of Beijing(Grant No.4252014).
文摘Nonlocal set of orthogonal product states(OPSs)can improve the confidentiality of information when it is used to design quantum cryptographic protocols.It is a difficult question how to construct a nonlocal set of OPSs on general multipartite and high dimensional quantum systems.Different from the previous works,we first present a novel method for constructing a nonlocal product set with 3d-2 members on C^(d)■C^(d)■C^(d)quantum system for d≥3.Then,we extend this construction method to C^(d_(1))■C^(d_(2))■C^(d_(3))quantum system and■_(i=1)^(n)C^(di)quantum system respectively,where 3≤d_(1)≤d_(2)≤d_(3)≤…≤dC_(d_(i))and n≥3.The nonlocal set of OPSs constructed by our method contains fewer elements than those constructed by the existing methods,except for one special case.More importantly,the set of states constructed by our method has a completely different structure from those constructed by the existing methods since our nonlocal set does not contain a“stopper”state.Our result is helpful to further understand the different structures of nonlocal sets on multipartite systems.
基金funded by the National Key Research and Development Program of China(2022YFC3003502)。
文摘Local strong seismic activity shows the potential to closely follow a renewal process,which is inconsistent with the overall seismic activity that aligns with the Poisson process.Given that existing methods for synthesizing stochastic seismic event sets cannot control local seismic activity,a method based on Monte Carlo simulations has been developed for synthesizing random seismic event sets where local strong earthquakes satisfy the renewal process.This method can synthesize seismic activities in a statistical area where the overall activity conforms to the Poisson process and the major seismic activities in local potential sources or faults follow the renewal process.This paper presents long-and short-scale approaches.The long-scale earthquake catalogs are suitable for reflecting the sequential characteristics of seismic activities.Meanwhile,the short-scale catalogs focus on the impacts of specific earthquake events within a group for a detailed understanding of hazards under certain conditions,making them suitable for studies on specific earthquake sequences and geological areas or situations requiring high temporal resolution.In the applications of shortscale sequences,we find that the equivalent occurrence rate method may overestimate the seismic hazard.This synthesis method for earthquake catalogs can simulate realistic seismic activities,thereby enhancing the accuracy of hazard analysis results and is suitable for seismic hazard analysis and earthquake insurance rate setting.
基金supported by the National Natural Science Foundation of China(Grant Nos.12372200 and 12072242).
文摘Parameterized level-set method(PLSM)has been proposed and developed for many years,and is renowned for its efficacy in ad-dressing topology optimization challenges associated with intricate boundaries and nucleation of new holes.However,most pertinent investigations in the field rely predominantly on fixed background mesh,which is never remeshed.Consequently,the mesh element partitioned by material interface during the optimization process necessitates approximation by using artificial interpolation models to obtain its element stiffness or other properties.This paper introduces a novel approach to topology op-timization by integrating the PLSM with body-fitted adaptive mesh and Helmholtz-type filter.Primarily,combining the PLSM with body-fitted adaptive mesh enables the regeneration of mesh based on the zero level-set interface.This not only precludes the direct traversal of the material interface through the mesh element during the topology optimization process,but also improves the accuracy of calculation.Additionally,the incorporation of a Helmholtz-type partial differential equation filter,relying solely on mesh information essential for finite element discretization,serves to regulate the topological complexity and the minimum feature size of the optimized structure.Leveraging these advantages,the topology optimization program demonstrates its versa-tility by successfully addressing various design problems,encompassing the minimum mean compliance problem and minimum energy dissipation problem.Ultimately,the result of numerical example indicates that the optimized structure exhibits a dis-tinct and smooth boundary,affirming the effective control over both topological complexity and the minimum feature size of the optimized structure.
基金Supported by the National Key Research and Development Program of China (2023YFB4102903)。
文摘This study systematically conducted preparation optimization and performance investigations on Co-modified Ce/TiO_(2) catalysts,with a focus on examining how preparation methods and Co loading regulate the catalyst’s low-temperature denitrification activity.After identifying optimal preparation parameters via condition screening,multiple characterization techniques-including BET,XRD,XPS,H_(2)-TPR and in situ DRIFTS-were employed to deeply analyze the catalyst’s physicochemical properties and reaction mechanism.Results demonstrated that compared to the impregnation and co-precipitation methods,the Ce-Co_(0.025)/TiO_(2)-SG catalyst(prepared by the sol-gel method with a Co/Ti mass ratio of 0.025)exhibited significantly superior denitrification activity:NO conversion remained stably above 95%in the 225−350℃ temperature range,and it displayed high N_(2) selectivity.Characterization analysis revealed that abundant surface oxygen vacancies,a high proportion of Ce^(3+) species,and prominent acidic sites collectively contributed to enhancing its low-temperature denitrification performance.This work provides reference value for the development of highly efficient low-temperature denitrification catalysts.
基金Supported in part by Natural Science Foundation of Guangxi(2023GXNSFAA026246)in part by the Central Government's Guide to Local Science and Technology Development Fund(GuikeZY23055044)in part by the National Natural Science Foundation of China(62363003)。
文摘In this paper,we consider the maximal positive definite solution of the nonlinear matrix equation.By using the idea of Algorithm 2.1 in ZHANG(2013),a new inversion-free method with a stepsize parameter is proposed to obtain the maximal positive definite solution of nonlinear matrix equation X+A^(*)X|^(-α)A=Q with the case 0<α≤1.Based on this method,a new iterative algorithm is developed,and its convergence proof is given.Finally,two numerical examples are provided to show the effectiveness of the proposed method.
基金support from the National Natural Science Foundation of China(Grant No.52278387).
文摘This study investigates the influence of the elastic modulus(E)of the composite strata on the trough width coefficient(i).It is hypothesized that,in composite strata,the relationship between the trough width coefficient(i)and the stratum thickness(H)follows a piecewise linear trend.Specifically,within strata of identical elastic modulus(E),i exhibits a linear correlation with H,while variations in E affect the slope of this correlation.Building upon the non-iterative analytical method(NIAM)for evaluating tunnel excavation responses in composite strata,this study proposes two novel approaches:the crucial point method(CPM)and the standard curve method(SCM).These methods incorporate the elastic modulus into the estimation of i.The values of i obtained via NIAM and refined through CPM and SCM are validated against field data using the parameter K.The results are consistent with existing research findings,thereby confirming the reliability of the proposed methodology.Furthermore,the study investigates the relationship between tunnel depth(h0)and tunnel radius(R),and explores the interactions among the layer number of stratum(n),elastic modulus(E),and layer thickness(H).A reduction coefficient(η)is introduced to improve the model's accuracy.The proposed approach is applied to nine tunnel engineering cases,and comparisons with measured data demonstrate its accuracy and practical applicability.
基金National Natural Science Foundation of China under Grant Nos.U2139208 and 52278516Key Laboratory of Earthquake Engineering and Engineering Vibration,China Earthquake Administration under Grant No.2024D15Key Laboratory of Soft Soil Characteristic and Engineering Environment,Tianjin Chengjian University under Grant No.2022SCEEKL003。
文摘This study presents an effective hybrid simulation approach for simulating broadband ground motion in complex near-fault locations.The approach utilizes a deterministic approach based on the spectral element method(SEM),which is used to simulate low-frequency ground motion(f<1 Hz)by incorporating an innovative efficient discontinuous Galerkin(DG)method for grid division to accurately model basin sedimentary layers at reduced costs.It also introduces a comprehensive hybrid source model for high-frequency random scattering and a nonlinear analysis module for basin sedimentary layers.Deterministic outcomes are combined with modified three-dimensional stochastic finite fault method(3D-EXSIM)simulations of high-frequency ground motion(f>1 Hz).A fourth-order Butterworth filter with zero phase shift is employed for time-domain filtering of low-and high-frequency time series at a crossover frequency of 1 Hz,merging the low and high-frequency ground motions into a broadband time series.Taking an Ms 6.8 Luding earthquake,as an example,this hybrid method was used for a rapid and efficient simulation analysis of broadband ground motion in the region.The accuracy and efficiency of this hybrid method were verified through comparisons with actually observed station data and empirical attenuation curves.Deterministic method simulation results revealed the effects of mountainous topography,basin effects,nonlinear effects within the basin’s sedimentary layers,and a coupling interaction between the basin and the mountains.The findings are consistent with similar studies,showing that near-fault sedimentary basins significantly focus and amplify strong ground motion,and the soil’s nonlinear behavior in the basin influences ground motion to varying extents at different distances from the fault.The mountainous topography impacts the basin’s response to ground motion,leading to barrier effects.This research provides a scientific foundation for seismic zoning,urban planning,and seismic design in nearfault mountain basin regions.
文摘Circumlunar abort trajectories constitute a vital contingency return strategy during the translunar phase of crewed lunar missions.This paper proposes a methodology for constructing the solution set of the circumlunar abort trajectory and leverages its advantageous properties to address the optimization design problem of abort trajectories.Initially,a solution set of all feasible abort trajectories,originating from an abort point on the nominal trajectory and complying with fundamental reentry constraints,is formulated through the introduction of two novel design parameters.Subsequently,the geometric characteristics of the solution set,as well as the distributional properties of key iterative constraint responses,including flight time and velocity increment,are analyzed.Finally,the characteristics exhibited in the solution set are employed to directly identify the design parameters of the abort trajectories with minimum flight time and velocity increment,thereby providing solutions to two distinct types of optimization problems.The simulation results for a variety of nominal trajectories,encompassing the reconstruction and redesign of the Apollo13 abort trajectory,validate the proposed method,demonstrating its ability to directly generate optimal abort trajectories.The method proposed in this paper investigates feasible abort trajectories from a global perspective,providing both a framework and convenience for mission planning and iterative optimization in abort trajectory design.
基金Supported by Shanghai Agriculture Applied Technology Development Program (Grant No.T20220120).
文摘[Objectives]This study was conducted to establish a quantitative assessment method for the textural quality of chieh-qua fruit.[Methods]Using two modes of a texture analyzer,namely TPA(texture profile analysis)and puncture,the index data of the fruit were obtained by setting different trigger forces,deformation levels,test speeds,as well as puncture speeds and puncture depths.The data included TPA hardness,adhesiveness,springiness,cohesiveness,gumminess,chewiness,resilience,as well as skin hardness,skin toughness,flesh hardness,fracturability,and compactness.[Results]Different deformation levels had a significant impact on all parameters.Hardness,adhesiveness,gumminess and chewiness showed a trend of first increasing and then decreasing with the deformation level increasing.When the deformation level was 30%,the adhesiveness,gumminess and chewiness reached their maximum values.When the deformation level was 50%,TPA hardness reached its maximum.When the compression speed was 3 mm/s,the measured values of TPA hardness,adhesiveness,chewiness,and resilience were at their maximums.The skin hardness varied significantly under different trigger forces.When the trigger force was 15 g,the skin hardness reached a maximum value of 944.63 g,and the skin toughness,flesh hardness,fracturability,and compactness also reach their maximum values respectively.When the puncture depth was 12 mm,the flesh hardness and skin toughness reached their maximums of 682.51 g and 1.82 mm,respectively.In the TPA mode,the flesh hardness of chieh-qua showed an extremely significant negative correlation with springiness,cohesiveness,and resilience(P<0.01).The fruit fracturability detected by puncture had an extremely significant positive correlation with compactness(P<0.01).[Conclusions]The evaluation method for measuring chieh-qua texture by combining TPA and the puncture mode could accurately and quantitatively reflect the differences in the flesh texture quality of chieh-qua.The optimal parameters for texture measurement of chieh-qua fruit were determined as a 15 g trigger force with 50%deformation and a 3 mm/s compression speed in TPA mode,and a 15 g trigger force with a 12 mm puncture depth in puncture mode.Puncture speed was found to have no significant effect on the texture indices of chieh-qua.
基金Project supported by the National Natural Science Foundation of China(Nos.52405095,12272089,and 92360305)the Guangdong Basic and Applied Basic Research Foundation of China(No.2023A1515110557)+4 种基金the Natural Science Foundation of Liaoning Province of China(No.2023-BSBA-102)the Open Fund of National Key Laboratory of Particle Transport and Separation Technology of China(No.WZKF-2024-6)the Open Project of Guangxi Key Laboratory of Automobile Components and Vehicle Technology of China(Nos.2024GKLACVTKF07 and 2024GKLACVTKF06)the Basic Research Projects of Liaoning Provincial Department of Education of China(No.JYTQN2023162)the Fundamental Research Funds for the Central Universities of China(No.N2403022)。
文摘The testing of large structures is limited by high costs and long cycles, making scaling methods an attractive solution. However, the scaling process of elastic rings introduces complexities in multi-parameter geometric distortions, leading to a diminution in the predictive accuracy of the distorted similitude. To address this challenge, this study formulates a novel set of scaling laws, tailored to account for the intricate geometric distortions associated with elastic rings. The proposed scaling laws are formulated based on the intrinsic deformation characteristics of elastic rings, rather than the traditional systemic governing equations. Numerical and experimental cases are conducted to assess the efficacy and precision of the proposed scaling laws, and the obtained results are compared with those achieved by traditional methods. The outcomes demonstrate that the scaling laws put forth by this study significantly enhance the predictive capabilities for deformations of elastic rings.
基金supported by the National Natural Science Foundation of China(Grant Nos.92252104,12388101,and 12472224).
文摘In this study,we perform particle-resolved simulations of settling spheroidal particles,considering oblate and prolate spheroids and spheres,and investigate the shape effect on the particle dynamics in suspensions with volume fraction 1%and 5%.We first examine the single-point statistics of the translational and rotational motion of the settling particles.The horizontal velocity has a symmetrical distribution with standard deviation dependent on the particle shape.The greater horizontal velocity fluctuations of the non-spherical particles,compared to that of spheres,are attributed to the horizontal drift of settling spheroids with oblique orientations induced by the fluid-particle and particle-particle interactions.The fluctuation of particle vertical velocity,instead,is skewed under the effect of wake-induced hydrodynamic interactions.Further,we explore the particle pair statistics,which demonstrate the formation of column-like particle micro-structures for the lowest volume fraction considered.This clustering is more pronounced for spheroidal particles than spheres,due to the stronger attractions among vertically-aligned settling spheroids.Moreover,the particle pair statistics are directly related to the collision rate among the dispersed particles.The local accumulation of oblate/prolate spheroids serves as the major mechanism to promote the particle-particle collisions in dilute suspensions.
基金supported in part by the Mining Hydraulic Technology and Equipment Engineering Research Center,Liaoning Technical University,Fuxin,China(Grant No.MHTE23-R04)the Fundamental Research Funds for the Central Universities(ID N25BSS068).
文摘This study presents an implicit multiphysics coupling method integrating Computational Fluid Dynamics(CFD),the Multiphase Particle-in-Cell(MPPIC)model,and the Finite Element Method(FEM),implemented with OpenFOAM,CalculiX,and preCICE to simulate fluid-particle-structure interactions with large deformations.Mesh motion in the fluid field is handled using the radial basis function(RBF)method.The particle phase is modeled by MPPIC,where fluid-particle interaction is described through momentum exchange,and inter-particle collisions are characterized by collision stress.The structural field is solved by nonlinear FEM to capture large deformations induced by geometric nonlinearity.Coupling among fields is realized through a partitioned,parallel,and non-intrusive iterative strategy,ensuring stable transfer and convergence of interface forces and displacements.Notably,the influence of particles on the structure is not direct but mediated by the fluid,while structural motion directly affects particle dynamics.The results demonstrate that the proposed approach effectively captures multiphysics interaction processes and provides a valuable reference for numerical modeling of coupled fluid-particle-structure systems.
基金supported by the Basic Science Research Program through the National Research Foundation of Korea(NRF),funded by the Ministry of Education(RS-2023-00248378 and NRF-2020R1A6A1A03043708).
文摘Objectives:Tamoxifen is a key drug that provides endocrine therapy for estrogen receptor(ER)α-positive breast cancer;however,resistance remains a significant clinical challenge.This study aims to investigate the molecular mechanisms of tamoxifen resistance in ERα-positive breast cancer,with particular focus on the role of SET Domain Containing 1A(SETD1A)-driven forkhead box A2(FOXA2)as a key regulator of this resistance.Methods:FOXA2 expression and its regulation by SETD1A were assessed via(quantitative polymerase chain reaction),western blotting,transcriptome profiling,and chromatin immunoprecipitation analyses.The effects of FOXA2 on cell proliferation,migration,invasion,and cancer stem cell traits were evaluated using small interfering RNA(siRNA)-mediated silencing.Clinical relevance was examined by analyzing patient datasets and tumor tissue microarrays.Results:FOXA2 expression was significantly elevated in tamoxifen-resistant(TamR)and ERα-negative breast cancer cells compared to that in ERα-positive MCF-7 cells,regardless of tamoxifen treatment or ERαdepletion.Transcriptome and chromatin immunoprecipitation analyses revealed that SETD1A,a histone methyltransferase,directly regulated FOXA2 expression.Functionally,FOXA2 knockdown inhibited the proliferation,migration,invasion,and cancer stem cell properties of TamR cells while restoring tamoxifen sensitivity.High FOXA2 expression was correlated with poor survival and reduced responsiveness to tamoxifen in patients with ER-positive breast cancer.Conclusion:Our findings identified FOXA2 as a key mediator of tamoxifen resistance regulated by SETD1A and suggested that targeting the SETD1A-FOXA2 axis may offer a novel strategy for overcoming endocrine resistance in breast cancer.
基金supported by the Fuxing Nursing Research Foundation of Fudan University[FNF202352].
文摘Objectives This review aimed to systematically synthesize the available research on the disclosure of diagnosis and related issues in childhood cancer from the perspectives of healthcare professionals,with the goal of informing the optimization of disclosure processes and meeting the communication needs of affected families.Methods In accordance with the Joanna Briggs Institute(JBI)methodology for mixed methods systematic reviews,the convergent segregated approach was used in this review.Articles were retrieved from 11 databases,including PubMed,Web of Science,CINAHL,CENTRAL,Embase,Ovid/Medline,PsycINFO,PsycArticles,Scopus,ERIC,and China National Knowledge Infrastructure(CNKI).The quality of the selected articles was assessed using the Mixed Method Appraisal Tool(MMAT).The review protocol was registered on PROSPERO(CRD42024542746).Results A total of 21 studies from 10 countries were included.Their methodological quality was generally medium to high,with MMAT scores ranging from 60%to 100%.The synthesis yielded three core themes:1)the spectrum of professional and societal attitudes toward disclosure;2)the dynamic practices of navigating disclosure amid uncertainty,including timing and environment,stakeholders,and content of disclosure;and 3)factors influencing disclosure,including children’s,parental,healthcare professionals’,and socio-cultural factors.Conclusions This review synthesized the perspectives and experiences of healthcare professionals regarding disclosure in childhood cancer,highlighting the complexity and multidimensional nature of this process in clinical practice.Future research should further investigate the experiences and needs of children and their parents,explore cultural variations in disclosure practices,develop context-appropriate assessment tools,and construct multidimensional intervention strategies to enhance the humanistic care and professional effectiveness of the disclosure process.
基金supported by the National Natural Science Foundation of China(Grant Nos.12272393 and 52130905).
文摘As binary geological media,soil-rock mixtures(SRMs)exhibit a distinct gradational composition,leading to their unique mechanical behaviors.To appraise the stability of SRM slopes,it is essential to determine equivalent parameters of SRMs,which are typically obtained through experimental and numerical methods.In contrasted to other numerical methods,the numerical manifold method(NMM)is more effective in addressing SRM problems.This is because the high-precision regular mathematical meshes in NMM can be used without aligning with the soil-rock interfaces and boundaries of SRMs.In the current research,the equivalent strength parameters of SRMs,i.e.the equivalent cohesion ce and internal friction angleϕ_(e),are determined using NMM.Initially,an NMM triaxial numerical model is established and validated based on triaxial experiments.Subsequently,the soil and rock parameters are derived through parameter inversion.Moreover,the impacts of rock content,size,shape and rock blocks'major-axis orientation on ce andϕ_(e) of SRMs are thoroughly examined using the NMM triaxial numerical model.Additionally,a fitting function is proposed to linkϕ_(e) to the rock content and size of SRMs.When other influencing factors are fixed,the above fitting model leads to the following conclusions:(1)the predictedϕ_(e) of SRMs increase with the increase of rock content;and(2)SRM samples with smaller rocks display a higher predictedϕ_(e).
