Objective: To observe the clinical efficacy of acupoint injection plus medication in treating recurrent facial dermatitis(RFD). Methods: Fifty-eight patients with RFD were randomized into a treatment group and a contr...Objective: To observe the clinical efficacy of acupoint injection plus medication in treating recurrent facial dermatitis(RFD). Methods: Fifty-eight patients with RFD were randomized into a treatment group and a control group, 29 in each. The treatment group was intervened by acupoint injection with BCG-PSN plus oral administration of Fexofenadine Hydrochloride, and the control group was by Fexofenadine Hydrochloride only. The clinical efficacies were compared between the two groups, and a follow-up study was conducted to investigate the recurrence rate. Results: The total effective rate was 96.6% in the treatment group versus 65.5% in the control group, and the difference was statistically significant(P<0.01). Of the cured and improved patients in the treatment group, the recurrence rates were 10.7%, 25.0%, and 32.1% respectively 3 months, 6 months, and 12 months after treatment, versus 31.6%, 36.8%, and 73.7% in the control group, and the differences were statistically significant(P<0.05). Conclusion: Acupoint injection plus medication is an effective method in treating RFD.展开更多
Objective:To compare the therapeutic effects of three different external wet compress methods on facial hormone dependent dermatitis(FCAD),and to provide reference for clinical treatment of FCAD.Methods:From June 2016...Objective:To compare the therapeutic effects of three different external wet compress methods on facial hormone dependent dermatitis(FCAD),and to provide reference for clinical treatment of FCAD.Methods:From June 2016 to June 2019,160 FCAD patients in our dermatology clinic were selected and divided into three groups according to random number table:the first group was treated with Compound Cortex Phellodendri liquid coating,the second group was treated with collagen paste dressing,and the third group was treated with 0.9%sodium chloride injection solution.Apply 8 layers of gauze or cold compress directly to the skin lesions for 4 weeks in each group.Results:After 4 weeks of treatment,no adverse reactions were found.The effective rates of the first group,the second group,and the third group were 72.22%,62.26%and 41.51%,respectively.Compared with the third group,the effective rate of the first group and the second group was significantly higher,and there was statistical significance between the groups(x2=10.294,x2=4.573,P<0.05);but there was no significant statistical difference between the first group and the second group(x2=1.205,P>0.05).Conclusion:Compound Cortex Phellodendri coating is suitable for FCAD patients with severe inflammation,collagen paste dressing is suitable for FCAD patients with mild to moderate inflammatory reaction and pigmentation,and 0.9%sodium chloride injection is suitable for patients with mild facial flushing and swelling.Clinical treatment should be selected according to the patient's condition and rash characteristics.展开更多
目的探究凉血清肺汤联合硝黄搽剂湿敷治疗面部脂溢性皮炎肺胃热盛证的临床效果。方法回顾性选取2022年1月—2023年1月期间收治的面部脂溢性皮炎肺胃热盛证患者102例,根据随机数字表法分为研究组(51例),常规组(51例)。常规组进行硝黄搽...目的探究凉血清肺汤联合硝黄搽剂湿敷治疗面部脂溢性皮炎肺胃热盛证的临床效果。方法回顾性选取2022年1月—2023年1月期间收治的面部脂溢性皮炎肺胃热盛证患者102例,根据随机数字表法分为研究组(51例),常规组(51例)。常规组进行硝黄搽剂湿敷治疗,研究组采用凉血清肺汤联合硝黄搽剂湿敷治疗。比较治疗结束后患者临床疗效,比较治疗结束后患者湿疹面积及严重程度指数(eczema area severity index,EASI)、整体评分(investigator′s global assessment,IGA)、基质金属蛋白酶-3(matrix metalloproteinase-3,MMP-3)、白细胞介素-1β(interleukin-1β,IL-1β)水平,并比较治疗期间的不良反应情况。结果治疗后,两组患者中医症状评分较治疗前均降低(P<0.05),且研究组低于常规组(P<0.05),研究组、常规组治疗总有效率分别为94.12%(48/51)、72.55%(37/51),研究组较常规组高(P<0.05),治疗后两组IGA、EASI评分降低,研究组较常规组低(P<0.05),两组面部脂溢性皮炎肺胃热盛证患者治疗后MMP-3、IL-1β水平降低,研究组MMP-3、IL-1β水平较常规组低(P<0.05),两组患者不良反应率比较,差异均无统计学意义(P>0.05)。结论凉血清肺汤联合硝黄搽剂湿敷能够提高面部脂溢性皮炎肺胃热盛证患者的临床疗效,缓解症状,降低IGA、EASI评分,改善血清炎症水平,安全性较高。展开更多
基金support of Lishui Central Hospital of Zhejiang Province
文摘Objective: To observe the clinical efficacy of acupoint injection plus medication in treating recurrent facial dermatitis(RFD). Methods: Fifty-eight patients with RFD were randomized into a treatment group and a control group, 29 in each. The treatment group was intervened by acupoint injection with BCG-PSN plus oral administration of Fexofenadine Hydrochloride, and the control group was by Fexofenadine Hydrochloride only. The clinical efficacies were compared between the two groups, and a follow-up study was conducted to investigate the recurrence rate. Results: The total effective rate was 96.6% in the treatment group versus 65.5% in the control group, and the difference was statistically significant(P<0.01). Of the cured and improved patients in the treatment group, the recurrence rates were 10.7%, 25.0%, and 32.1% respectively 3 months, 6 months, and 12 months after treatment, versus 31.6%, 36.8%, and 73.7% in the control group, and the differences were statistically significant(P<0.05). Conclusion: Acupoint injection plus medication is an effective method in treating RFD.
文摘Objective:To compare the therapeutic effects of three different external wet compress methods on facial hormone dependent dermatitis(FCAD),and to provide reference for clinical treatment of FCAD.Methods:From June 2016 to June 2019,160 FCAD patients in our dermatology clinic were selected and divided into three groups according to random number table:the first group was treated with Compound Cortex Phellodendri liquid coating,the second group was treated with collagen paste dressing,and the third group was treated with 0.9%sodium chloride injection solution.Apply 8 layers of gauze or cold compress directly to the skin lesions for 4 weeks in each group.Results:After 4 weeks of treatment,no adverse reactions were found.The effective rates of the first group,the second group,and the third group were 72.22%,62.26%and 41.51%,respectively.Compared with the third group,the effective rate of the first group and the second group was significantly higher,and there was statistical significance between the groups(x2=10.294,x2=4.573,P<0.05);but there was no significant statistical difference between the first group and the second group(x2=1.205,P>0.05).Conclusion:Compound Cortex Phellodendri coating is suitable for FCAD patients with severe inflammation,collagen paste dressing is suitable for FCAD patients with mild to moderate inflammatory reaction and pigmentation,and 0.9%sodium chloride injection is suitable for patients with mild facial flushing and swelling.Clinical treatment should be selected according to the patient's condition and rash characteristics.
文摘目的探究凉血清肺汤联合硝黄搽剂湿敷治疗面部脂溢性皮炎肺胃热盛证的临床效果。方法回顾性选取2022年1月—2023年1月期间收治的面部脂溢性皮炎肺胃热盛证患者102例,根据随机数字表法分为研究组(51例),常规组(51例)。常规组进行硝黄搽剂湿敷治疗,研究组采用凉血清肺汤联合硝黄搽剂湿敷治疗。比较治疗结束后患者临床疗效,比较治疗结束后患者湿疹面积及严重程度指数(eczema area severity index,EASI)、整体评分(investigator′s global assessment,IGA)、基质金属蛋白酶-3(matrix metalloproteinase-3,MMP-3)、白细胞介素-1β(interleukin-1β,IL-1β)水平,并比较治疗期间的不良反应情况。结果治疗后,两组患者中医症状评分较治疗前均降低(P<0.05),且研究组低于常规组(P<0.05),研究组、常规组治疗总有效率分别为94.12%(48/51)、72.55%(37/51),研究组较常规组高(P<0.05),治疗后两组IGA、EASI评分降低,研究组较常规组低(P<0.05),两组面部脂溢性皮炎肺胃热盛证患者治疗后MMP-3、IL-1β水平降低,研究组MMP-3、IL-1β水平较常规组低(P<0.05),两组患者不良反应率比较,差异均无统计学意义(P>0.05)。结论凉血清肺汤联合硝黄搽剂湿敷能够提高面部脂溢性皮炎肺胃热盛证患者的临床疗效,缓解症状,降低IGA、EASI评分,改善血清炎症水平,安全性较高。
