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Distribution,types,metallogenic regularity and exploration potential analysis of zirconium deposit in China
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作者 Qiong-wen Liang Yong-shen Li +8 位作者 Ying-cai Sun De-gao Zhai Hai-rui Sun Shi-xu Zhou Bang-lu Zhang Xin Lü Jin-chi Xu Xue-feng Li Yi-lun Du 《China Geology》 2025年第2期408-430,共23页
Zirconium,prized for its exceptional corrosion resistance,high melting point,and unique nuclear properties,plays a critical role in multiple industrial sectors globally.Zirconium deposits are categorized into endogene... Zirconium,prized for its exceptional corrosion resistance,high melting point,and unique nuclear properties,plays a critical role in multiple industrial sectors globally.Zirconium deposits are categorized into endogenetic and exogenetic types in China.Endogenetic deposits-including alkaline rock-,alkaline granite-,and pegmatite-type mineralizations-predominantly occur along the Tarim Craton’s northern margin,the North China Craton,the southern Greater Khingan metallogenic belt,and the Yangtze Craton’s western margin.Exogenetic deposits,comprising clastic sedimentary,weathering crust,and fragmentation types,are concentrated in South China’s coastal zones.Endogenetic mineralization formed during Permian-Cretaceous magmatic-hydrothermal events linked to evolved alkaline granitic systems,while exogenetic deposits developed in Quaternary periods through weathering of zirconium-rich protoliths.However,economic extraction of endogenetic deposits remains constrained by rare earth element(REE)associations and radioactive complexities.Currently,China’s most economically significant reserves derive from clastic sedimentary systems,particularly coastal placer deposits.This study systematically synthesizes the spatial distribution and metallogenic mechanisms of Chinese zirconium deposits,offering strategic insights for resource exploration and sustainable utilization. 展开更多
关键词 Zirconium deposit Metallogenic regularity Critical mineral resources Prospecting potential Geological survey engineering
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Regularity criteria of weak solutions to the 3D axisymmetric Navier-Stokes equations
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作者 ZHAO Ji-hong 《Applied Mathematics(A Journal of Chinese Universities)》 2025年第4期773-784,共12页
We investigate a sufficient condition,in terms of the azimuthal componentω^(θ)ofω=curl u in cylindrical coordinates,for the regularity of axisymmetric weak solutions to the 3D incompressible Navier-Stokes equations... We investigate a sufficient condition,in terms of the azimuthal componentω^(θ)ofω=curl u in cylindrical coordinates,for the regularity of axisymmetric weak solutions to the 3D incompressible Navier-Stokes equations.More precisely,we prove that if■,then the weak solution u is actually a regular solution.Similar regularity criterion still holds in the homogeneous Triebel-Lizorkin spaces. 展开更多
关键词 Navier-Stokes equations axisymmetric weak solutions regularity criteria Besov spaces
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Uniform regularity for the Navier-Stokes-Fourier system in T^(n)
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作者 FAN Ji-shan ZHOU Yong 《Applied Mathematics(A Journal of Chinese Universities)》 2025年第2期501-508,共8页
In this paper,we prove the uniform regularity estimates for the Navier-Stokes-Fourier system in T^(n).
关键词 Navier-Stokes-Fourier regularity smooth solutions
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C^(1,1) REGULARITY FOR SOLUTIONS TO THE DEGENERATE DUAL ORLICZ-MINKOWSKI PROBLEM
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作者 Di WU 《Acta Mathematica Scientia》 2025年第2期327-337,共11页
In this paper,C1,1 regularity for solutions to the degenerate dual Orlicz-Minkowski problem is considered.The dual Orlicz-Minkowski problem is a generalization of the Lp dual Minkowski problem in convex geometry.The p... In this paper,C1,1 regularity for solutions to the degenerate dual Orlicz-Minkowski problem is considered.The dual Orlicz-Minkowski problem is a generalization of the Lp dual Minkowski problem in convex geometry.The proof is adapted from Guan-Li[17]and Chen-Tu-Wu-Xiang[11]. 展开更多
关键词 C^(1 1)regularity Monge-Ampere type equation dual Orlicz-Minkowski problem
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Occurrence Regularity and Control Research of Apple Early Defoliation Disease in West Sichuan Plateau 被引量:2
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作者 杨文渊 谢红江 +5 位作者 陈善波 江国良 陈栋 涂美艳 李靖 孙淑霞 《Plant Diseases and Pests》 CAS 2011年第5期25-27,68,共4页
[ Objective ] The research aimed to discuss the occurrence regularity of apple early defoliation disease and control effects of fungicides in west Sichuan plateau. [ Method ] Apple early defoliation disease in west Si... [ Objective ] The research aimed to discuss the occurrence regularity of apple early defoliation disease and control effects of fungicides in west Sichuan plateau. [ Method ] Apple early defoliation disease in west Sichuan plateau was systematically investigated during 2009 and 2011, and the control effects of different fungicides during different spraying periods were studied. [ Result] The species of pathogen mainly was Marssonina ma/i ( P. Henn), accounting for 32.5%, Phyl-losticta Pirina Sa accounted for 29.9%, and Alternaria mali Roberts accounted for 25.7%. The field fluctuation regularity was as follows : the disease generally be- gan in the mid-May and ended in early and middle October with only one damage peak during the whole year, the fluctuation had positive correlation with rainfall ( R2 =0.891 8 * * ). Control test showed that 40% flusilazole had the best control effect (86.5%), which was best to apply after anthesis. [ Conclusion ] The paper provided theoretical basis for the effective control against apple early defoliation disease. 展开更多
关键词 APPLE Early defoliation disease Occurrence regularity Control effect China
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定期成分献血者血常规相关指标分析
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作者 于媛 谯铭铭 +2 位作者 王娜 徐昊 陈元锋 《中国实用医药》 2026年第2期37-42,共6页
目的对山东省血液中心定期成分献血者外周血血常规指标进行回顾性分析,探讨献血次数及不同机型血细胞分离机对血常规的影响,以期为献血者的关爱与保护及定期成分献血者队伍建设提供参考。方法在唐山启奥科技SHINOW 9.5系统中调取2024年2... 目的对山东省血液中心定期成分献血者外周血血常规指标进行回顾性分析,探讨献血次数及不同机型血细胞分离机对血常规的影响,以期为献血者的关爱与保护及定期成分献血者队伍建设提供参考。方法在唐山启奥科技SHINOW 9.5系统中调取2024年2月X、Y两个献血屋的献血者资料,从中选取从未捐献过全血并且在2018年2月~2024年2月间只采用同一种A或B机型血细胞分离机进行采集的献血者,调取血常规相关指标数据按照男女性别分别进行不同频次、不同机型分析。将选出的献血者按照男女分别进行分组:2月份初次前来即以往从未捐献过的献血者作为初次组;1次≤捐献次数<3次的成分献血者设为偶尔献血组;≥第4次前来捐献即已经捐献次数≥3次的成分献血者作为定期献血组;定期献血者中≥第21次前来捐献即已经捐献次数≥20次的成分献血者设为较高频次定期献血组;在较高频次定期献血组内再按采集机型不同分为A机型组、B机型组。男性:初次组25人,偶尔献血组21人,定期献血组79人,其中较高频次定期献血组29人;较高频次定期献血组的A机型组12人,B机型组17人。女性:初次组5人,偶尔献血组4人,定期献血组8人,其中较高频次定期献血组3人;较高频次定期献血组的A机型组1人,B机型组2人。比较各组男性的血常规相关指标[血红蛋白浓度(HGB)、血小板计数(PLT)、红细胞压积(HCT)、红细胞计数(RBC)、白细胞计数(WBC)、平均红细胞体积(MCV)、平均红细胞血红蛋白量(MCH)、平均红细胞血红蛋白浓度(MCHC)、淋巴细胞计数、淋巴细胞百分比、平均血小板体积(MPV)],初次组与采用不同机型的较高频次定期献血组男性的血常规相关指标,各组女性的血常规相关指标。结果较高频次定期献血组男性的WBC、HGB、HCT分别为5.00(4.30,5.65)×10^(9)/L、145.00(140.50,155.00)g/L、44.00(42.00,46.00)%,均明显低于初次组男性的6.20(5.50,6.85)×10^(9)/L、153.00(150.00,160.50)g/L、46.00(45.00,48.00)%,具有统计学意义(经Bonferroni校准后,P=0.003、0.028、0.021<0.05);较高频次定期献血组男性与初次组男性其他指标相比均没有统计学差异(P>0.05)。各组男性RBC、PLT、MCV、MCH、MCHC、淋巴细胞计数、淋巴细胞百分比、MPV两两相比均没有统计学差异(P>0.05)。B机型组男性RBC 4.80(4.70,5.20)×10^(12)/L、WBC 4.90(4.25,5.65)×10^(9)/L、HGB 144.00(138.50,151.00)g/L、HCT 43.00(42.00,44.00)%、淋巴细胞计数1.70(1.40,1.85)×10^(9)/L、MPV 9.50(9.10,9.85)fl均低于初次组男性的5.10(5.00,5.30)×10^(12)/L、6.20(5.50,6.85)×10^(9)/L、153.00(150.00,160.50)g/L、46.00(45.00,48.00)%、2.10(1.65,2.60)×10^(9)/L、9.90(9.65,10.35)fl,具有统计学意义(经Bonferroni校准后,P=0.022、0.001、0.001、0.000、0.044、0.023<0.05);B机型组男性HCT 43.00(42.00,44.00)%低于A机型组男性的45.00(44.00,47.00)%,具有统计学意义(经Bonferroni校准后,P=0.017<0.05)。其他相关指标相比均没有统计学差异(P>0.05)。17例女性的血常规相关指标数据均在可接受范围内,因样本数较少,未进行统计学比较。结论采集频次和采集机型不同对定期成分献血者血常规相关指标是有影响的,均在可接受范围内波动。工作人员需严格执行国家标准,建议根据献血者自身采集频次选择适宜机型,对定期献血者实行关爱和保护。 展开更多
关键词 定期成分献血 血常规 血细胞分离机
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Factors affecting headway regularity on bus routes 被引量:5
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作者 张曼 李文权 《Journal of Southeast University(English Edition)》 EI CAS 2013年第1期99-102,共4页
The common phenomenon of uneven headway in bus service is explored based on the automatic vehicle location (AVL) data of Route 2 in Yichun City of Jiangxi province from 6:00 to 9:00 in the morning. The headway reg... The common phenomenon of uneven headway in bus service is explored based on the automatic vehicle location (AVL) data of Route 2 in Yichun City of Jiangxi province from 6:00 to 9:00 in the morning. The headway regularity of two stages 6: 00--7:00 and 7: 00--9:00 is comparatively analyzed, and it is found that both the traffic conditions and the passenger demand affect headway regularity. A bus arrival model, which assumes that the dwell time of a bus is linear in headway, is built to probe the effect of scheduled headway, and the model is simulated by Matlab. The simulation results reveal that the departure intervals and fluctuations affect headway regularity. Longer intervals and less fluctuation mean higher regularity of headway. And, the fluctuation has a more obvious influence on headway regularity than the interval. Controlling the fluctuations of scheduled headway can effectively raise the regularity of headway and improve the level of public transport service. 展开更多
关键词 traffic engineering bus scheduling headway regularity scheduled headway bus bunching
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Detection of an increase in EMG regularity during fatiguing contractions 被引量:2
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作者 陈伟婷 曹桂涛 王志中 《Journal of Southeast University(English Edition)》 EI CAS 2010年第4期541-545,共5页
The changes in the evolvement patterns of surface electromyography(EMG)signals during both static and dynamic fatiguing contractions are studied.The main finding is that the EMG signal tends to be more and more regu... The changes in the evolvement patterns of surface electromyography(EMG)signals during both static and dynamic fatiguing contractions are studied.The main finding is that the EMG signal tends to be more and more regular as muscle fatigues.An increase in the summation of all the regular evolvement patterns denoted by Dreg reflects such a tendency.Compared with traditional measurements,Dreg shows less variability among subjects when characterizing a fatigue process.In addition,the calculation of Dreg in the time domain is free from the restrictions disturbing those of spectral parameters.The detection of an increase in the EMG regularity not only proposes a new and easy way to inspect changes in EMG during the fatigue process,but also provides strong supports to estimate muscle fatigue by means of nonlinear analysis methods such as entropy and complexity measures.The detection method of signal regularity can also be applied to other physiological signals. 展开更多
关键词 muscle fatigue surface electromyography(EMG) regularity
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Effects of Primary and Secondary Trunk Girdling on the Status and Distribution Regularity of Nutrients in Grape 被引量:1
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作者 张永福 王定康 +1 位作者 莫丽玲 董翠莲 《Agricultural Science & Technology》 CAS 2016年第12期2763-2768,共6页
Objective] The study aimed to investigate the effects of primary and sec-ondary trunk girdling on the status and distribution regularity of nutrients in grape. [Method] Using grape cultivar ‘Rose Honey’ as the exper... Objective] The study aimed to investigate the effects of primary and sec-ondary trunk girdling on the status and distribution regularity of nutrients in grape. [Method] Using grape cultivar ‘Rose Honey’ as the experimental material, the ef-fects of primary and secondary trunk girdling on carbon and nitrogen nutrition, min-eral nutrition and nutrient distribution regularity in leaves and branches above the girdling wound and roots below the girdling wound were analyzed. [Result] Girdling could significantly increase non-structural carbohydrate content (such as soluble sugar and starch) in branches above the girdling wound, reduce soluble protein and total nitrogen contents, and significantly improve C/N ratio. Specifical y, the highest C/N ratio in primary girdling group and secondary girdling group was 9.04 and 5.35, respectively, but C/N ratio in control group was only 4.89 in the same period. Girdling not only significantly decreased the content of non-structural carbohydrates (such as soluble sugar and starch) in roots, but also significantly declined soluble protein and total nitrogen content, which also reduced C/N ratio in various degrees. Specifical y, the lowest C/N ratio in primary girdling group and secondary girdling group was 1.16 and 3.06, respectively, while that in control group was 3.15 in the same period. ln addition, primary girdling exerted much greater effects on carbon and nitrogen nutrition than secondary girdling. Moreover, girdling significantly de-creased the contents of phosphorus, potassium, ferrum and copper in grape leaves, branches and roots. Specifical y, primary girdling exerted greater effects on ferrum and copper contents in leaves and branches. The contents of ferrum and copper in the first batch of samples exhibited significant differences between primary girdling group and control group: ferrum content in leaves was 75.05 μg/g DW in primary girdling group and that in control group was 85.29 μg/g DW; ferrum content in branches was 76.45 ?g/g DW in primary girdling group and copper content was 7.82 μg/g DW, while ferrum and copper contents in control group were 95.96 and 10.74 μg/g DW, respectively. [Conclusion] This study provided the basis for accu-rately regulating tree nutrition and ensuring safe and effective use of girdling tech-nique in ‘Rose Honey’ production. 展开更多
关键词 GRAPE GIRDLING Tree Nutrition Distribution regularity
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Study on the Occurrence and Epidemic Regularity and Region Division of Rice Blast in Nanchong City 被引量:1
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作者 彭昌家 白体坤 +2 位作者 丁攀 冯礼斌 杨宇衡 《Agricultural Science & Technology》 CAS 2016年第4期927-937,共11页
With the aim to improve the level of monitoring and warning as well as the comprehensive control of rice blast disease, and to feasibly reduce the disease threat in Nanchong City, the methods of GPS and GIS, systemati... With the aim to improve the level of monitoring and warning as well as the comprehensive control of rice blast disease, and to feasibly reduce the disease threat in Nanchong City, the methods of GPS and GIS, systematical monitoring and field survey, rice blast resistance identification, physiologic races of rice blast monitoring, and meteorological data analysis were performed to study the occurrence and epidemic region division, precise demarcation and occurrence and epidemic regularity of rice blast in Nanchong City. This study first completed the epidemic region division and precise demarcation; first clarified the initial affection(beginning period) locations, occurrence characteristics, epidemic trends and characteristics; explicated the existence of four epidemic peak periods of rice blast in the field, where the damage areas of first peak period played a decisive role during the blast epidemic years; in late May, the cumulative occurrence areas and annual occurrence areas presented higher positive correlation with the correlation coefficient of 0.817;and established a prediction model of occurrence areas per year based on the disease field rate at the end of boot stages and the diseased plant rate at dough stages. The results of investigation on the impact factors investigation of blast disease in Nanchong in recent years suggested that the internal causes were the decrease or loss of blast resistance of the rice cultivars, as well as the increase of physiological races with strong resistance to rice blast and the emergence of new virulent physiologic varieties; the external causes were suitable temperature, too much rainy, and sunlight shortage. Between 2010 and 2015, the short-term forecast accuracy for rice blast in Nanchong was up to 100%, and medium-and long-term forecast accuracy was also up to 98% and 95%, respectively, which increased by 5-15% than that before 1997, thereby making the control effect of rice blast in Nanchong increased by 15-30%. 展开更多
关键词 Rice Rice blast Region division Occurrence characteristics Epidemic regularity Early warning level
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Data-Path Placement Based on Regularity Extraction and Implementation
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作者 杨长旗 洪先龙 +2 位作者 蔡懿慈 经彤 吴为民 《Journal of Semiconductors》 EI CAS CSCD 北大核心 2004年第8期925-936,共12页
An algorithm named DPP is addressed.In it,a new model based on the concept of irregularity degree is founded to evaluate the regularity of cells.It generates the structure regularity of cells by exploiting the signal ... An algorithm named DPP is addressed.In it,a new model based on the concept of irregularity degree is founded to evaluate the regularity of cells.It generates the structure regularity of cells by exploiting the signal flow of circuit.Then,it converts the bit slice structure to parallel constraints to enable Q place algorithm.The design flow and the main algorithms are introduced.Finally,the satisfied experimental result of the tool compared with the Cadence placement tool SE is discussed. 展开更多
关键词 Data Path regularity extraction bit slice structure Q place
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PARTIAL REGULARITY FOR MINIMIZERS OF HIGHER ORDER QUASICONVEX FUNCTIONALS
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作者 吴在德 李君湘 梁汲廷 《Transactions of Tianjin University》 EI CAS 1997年第1期90-92,共3页
We consider the following quasiconvex functional I(u)=∫ Gf(x,δu,D mu) d x where u is a vector valued function in W m,p (G),m>1 and p>2. The partial C m,a —regularity is proved fo... We consider the following quasiconvex functional I(u)=∫ Gf(x,δu,D mu) d x where u is a vector valued function in W m,p (G),m>1 and p>2. The partial C m,a —regularity is proved for minimizers of I(u) under weaker conditions. 展开更多
关键词 higher order functional blow up technique partial regularity
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ON EXISTENCE, UNIQUENESS AND REGULARITY OF STEADY STATE SOLUTIONS TO THE BASIC SEMICONDUCTOR EQUATIONS
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作者 王元明 樊继山 《Acta Mathematica Scientia》 SCIE CSCD 1995年第2期180-188,共9页
Ealstence and regularity of steady state solutions to the basic semiconductor equations with the non-monotone net recombination rate are proved. A sufficient condition for the uniqueness of the steady state solutions ... Ealstence and regularity of steady state solutions to the basic semiconductor equations with the non-monotone net recombination rate are proved. A sufficient condition for the uniqueness of the steady state solutions is given. The uniqueness result is very general which contains almost all known conclusions. 展开更多
关键词 semiconductor equations EXISTENCE UNIQUENESS regularity.
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A NOTE ON REGULARITY FOR A CLASS OF QUASILINEAR ELLIPTIC EQUATIONS
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作者 Li Junjie Bian BaojunDept.of Math.,Zhejiang Univ.,Hangzhou31 0 0 2 7 《Applied Mathematics(A Journal of Chinese Universities)》 SCIE CSCD 2000年第3期273-280,共8页
The following regularity of weak solutions of a class of elliptic equations of the form are investigated, div A(x,u,Du)+B(x,u,Du)=0 in Ω.(*) Here Ω R n is a bounded domain, A(x,z,p)=(A 1(x,z,p),A 2(x,z,p),.... The following regularity of weak solutions of a class of elliptic equations of the form are investigated, div A(x,u,Du)+B(x,u,Du)=0 in Ω.(*) Here Ω R n is a bounded domain, A(x,z,p)=(A 1(x,z,p),A 2(x,z,p),...,A n(x,z,p)) and B(x,z,p) satisfy 1Λ(κ+|p|) m|ξ| 2≤ ο A i ο p j(x,z,p)ξ iξ j≤Λ(κ+|p|) m|ξ| 2, |A(x,z,p)-A(y,w,p)|≤(1+|p|) m+1 φ(|x-y|+|z-w| and |B(x,z,p)|≤Λ(1+|p|) m+2 for all (x,z,p),(y,m,p)∈Ω× R×R n and all ξ∈ R n,where m≥0,κ≥0,Λ>0 and φ(r) is a bounded increasing function in [0,∞). The results of the paper are:a) if lim r→0 + φ(r)=φ(0)=0 ,then any bounded solution of (*) belongs to C β loc ( Ω ) for any β∈(0,1) ;b) if m =0,and φ(r) is Dini continuous,that is,lim r→0 + φ(r)=φ(0)=0, ∫ 1 0φ(r)r d r<+∞, then any bounded solution of (*) ∈ C 1 loc ( Ω ). 展开更多
关键词 Elliptic equation regularity.
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Load of the Small-Scale Vertical Cylinder in a Wave-Current Field
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作者 Mingjie Li Binbin Zhao Wengyang Duan 《哈尔滨工程大学学报(英文版)》 2026年第1期82-94,共13页
Studies of wave-current interactions are vital for the safe design of structures.Regular waves in the presence of uniform,linear shear,and quadratic shear currents are explored by the High-Level Green-Naghdi model in ... Studies of wave-current interactions are vital for the safe design of structures.Regular waves in the presence of uniform,linear shear,and quadratic shear currents are explored by the High-Level Green-Naghdi model in this paper.The five-point central difference method is used for spatial discretization,and the fourth-order Adams predictor-corrector scheme is employed for marching in time.The domain-decomposition method is applied for the wave-current generation and absorption.The effects of currents on the wave profile and velocity field are examined under two conditions:the same velocity of currents at the still-water level and the constant flow volume of currents.Wave profiles and velocity fields demonstrate substantial differences in three types of currents owing to the diverse vertical distribution of current velocity and vorticity.Then,loads on small-scale vertical cylinders subjected to regular waves and three types of background currents with the same flow volume are investigated.The maximum load intensity and load fluctuation amplitude in uniform,linear shear,and quadratic shear currents increase sequentially.The stretched superposition method overestimates the maximum load intensity and load fluctuation amplitude in opposing currents and underestimates these values in following currents.The stretched superposition method obtains a poor approximation for strong nonlinear waves,particularly in the case of the opposing quadratic shear current. 展开更多
关键词 Wave-current interaction Cylinder load HLGN model Morison equation Regular waves
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积分收缩条件下一类二阶中立型发展方程的T-可控性
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作者 王甜甜 范虹霞 《浙江大学学报(理学版)》 北大核心 2026年第1期63-70,118,共9页
研究了在Hilbert空间中的一类二阶中立型发展方程适度解的存在唯一性和T-可控性。利用余弦族理论、正则积分收缩条件(较Lipschitz连续弱的条件)和迭代技术,证明了一类二阶中立型发展方程适度解的存在唯一性,并结合算子的单调性与强制性... 研究了在Hilbert空间中的一类二阶中立型发展方程适度解的存在唯一性和T-可控性。利用余弦族理论、正则积分收缩条件(较Lipschitz连续弱的条件)和迭代技术,证明了一类二阶中立型发展方程适度解的存在唯一性,并结合算子的单调性与强制性假设,获得了其T-可控性的充分条件。最后,通过实例验证了结果的正确性。 展开更多
关键词 T-可控性 中立型发展方程 正则积分收缩 迭代技术
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基于计算预测与斑马鱼观察雷公藤甲素治疗系统性红斑狼疮的效-毒研究
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作者 季宇鑫 林彦 +3 位作者 冯鑫煜 王雨 张晓朦 张冰 《中国药物警戒》 2026年第1期12-18,共7页
目的探讨雷公藤甲素(Triptolide,TP)器官毒性发生与时序规律、剂量蓄积的关系,初步分析其疗效-毒性机制,为提高TP临床使用安全性提供参考。方法以2 dpf斑马鱼胚胎为模型,设置荧光标记TP暴露组,于72 h后动态观察心脏、肝脏、肾脏及胃肠... 目的探讨雷公藤甲素(Triptolide,TP)器官毒性发生与时序规律、剂量蓄积的关系,初步分析其疗效-毒性机制,为提高TP临床使用安全性提供参考。方法以2 dpf斑马鱼胚胎为模型,设置荧光标记TP暴露组,于72 h后动态观察心脏、肝脏、肾脏及胃肠道毒性出现顺序及相关表型改变;利用网络药理学与网络毒理学筛选TP治疗系统性红斑狼疮及器官毒性共同靶点,进行GO/KEGG富集分析。结果TP可依次诱发斑马鱼肝脏(72 h)、心脏(74 h)、胃肠道(78 h)及肾脏(80 h)损伤;富集分析提示其“效-毒”机制高度相似,其潜在分子机制与凋亡、炎症反应等通路相关,白蛋白或为TP器官毒性标志指标。结论TP所致器官毒性呈现明显时序性与剂量依赖性,其“效-毒”潜在机制高度相似提示其疗效与毒性关系可能与剂量蓄积有关,其结果可为临床时序性毒性监测与干预提供参考,为临床防治提供新策略。但斑马鱼在药物代谢以及结构与人类存在差异,其器官毒性顺序需结合临床案例研究补充。 展开更多
关键词 雷公藤甲素 器官毒性 时序规律 分子机制 斑马鱼 中药药物警戒
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一类分数阶椭圆方程反边值问题的指数型正则化方法
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作者 郭亮 王泽文 +1 位作者 邱淑芳 张文 《应用数学》 北大核心 2026年第1期245-257,共13页
本文研究Tricomi-Gellerstedt-Keldysh型分数阶椭圆方程的侧边值反演问题,给出一种基于指数型Tikhonov正则化的重建方法,并在指数算子的Hilbert空间中建立了反问题的Hölder型稳定性条件.针对先验和后验选取正则化参数的两种情形,... 本文研究Tricomi-Gellerstedt-Keldysh型分数阶椭圆方程的侧边值反演问题,给出一种基于指数型Tikhonov正则化的重建方法,并在指数算子的Hilbert空间中建立了反问题的Hölder型稳定性条件.针对先验和后验选取正则化参数的两种情形,分别给出了侧边值正则化解的收敛性估计,并证明该正则化方法对一般平方可积函数是可行而有效的.最后,数值实验表明所提方法在低信噪比情况下依然具有良好的效果. 展开更多
关键词 分数阶椭圆方程 反边值问题 指数型正则化 正则化参数 收敛性估计
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Differentiation regularity of urban-rural equalized development at prefecture-level city in China 被引量:55
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作者 LIU Yansui CHEN Cong LI Yurui 《Journal of Geographical Sciences》 SCIE CSCD 2015年第9期1075-1088,共14页
The urban-rural equalized development (URED) as a definite measure and operating model is beneficial to gradually eliminating the dual-track structure of urban-rural development, bridging the gap of urban-rural deve... The urban-rural equalized development (URED) as a definite measure and operating model is beneficial to gradually eliminating the dual-track structure of urban-rural development, bridging the gap of urban-rural development, and creating harmonious urban-rural interactions. This paper aims to explore the status quo of URED in China at prefecture level, and to reveal the spatio-temporal patterns of URED and its differentiation regularity. The results show that: (1) China's URED level can be categorized into two parts, i.e., the eastern and the western, according to the "HU Huanyong Line", presenting a pattern of "east high and west low" and the URED level improves on the whole with the increase of distance from the line; (2) China's URED level can also be categorized into the northern and the southern parts according to "Kunlun-Qinling-Huaihe Line", presenting a pattern of "north high and south low", and the URED level reduces on the whole with the increase of distance from the line; (3) At the national level, China's URED has a significant trend of spatial agglomeration, the high and low URED regions tend to be adjacent, namely, the URED level presents obvious regional unbalance; (4) The five sub-dimension indicators of the URED level in the geographical space also reveal similar regional differentiation pattern, and in the aspect of space a decreasing trend is found in the URED level from the eastern (northern coast, eastern coast and southern coast), the northeastern, the central (the middle reaches of the Yangtze River and the Yellow River) to the western (northwest and southwest); and (5) China's URED at prefecture-level city can be divided into five types of differentiation areas. This study contributes to promoting the integrative cognition of the status quo of China's URED and can serve as a scientific ref- erence concerning the decision-making of coordinating urban-rural development and of pushing forward new-type urbanization strategy in China. 展开更多
关键词 urban-rural equalized development urban-rural development transformation URBANIZATION rural disease differentiation regularity China
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医院工程建设中项目管理的关键问题与对策研究
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作者 许金锁 《城市建筑》 2026年第2期213-216,共4页
文章聚焦医院工程建设项目管理,深入剖析其关键问题并提出应对策略。通过阐述医院工程建设项目的特点,详细分析了项目需求、进度控制、成本控制、质量控制及风险管理等方面存在的问题。同时,结合南通大学附属医院新建病房楼(平疫结合)... 文章聚焦医院工程建设项目管理,深入剖析其关键问题并提出应对策略。通过阐述医院工程建设项目的特点,详细分析了项目需求、进度控制、成本控制、质量控制及风险管理等方面存在的问题。同时,结合南通大学附属医院新建病房楼(平疫结合)项目案例,有针对性地提出完善需求分析与规划设计、强化进度控制与协调机制、优化成本控制与资金管理、提升质量控制能力及加强风险管理机制等对策。旨在为提高医院工程建设项目的管理水平提供理论与实践指导,确保项目顺利实施,满足医疗服务需求。 展开更多
关键词 医院工程建设 项目管理 关键问题 对策 平疫结合
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