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Multi-objective ANN-driven genetic algorithm optimization of energy efficiency measures in an NZEB multi-family house building in Greece
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《建筑节能(中英文)》 2026年第2期62-62,共1页
The goal of the present work is to demonstrate the potential of Artificial Neural Network(ANN)-driven Genetic Algorithm(GA)methods for energy efficiency and economic performance optimization of energy efficiency measu... The goal of the present work is to demonstrate the potential of Artificial Neural Network(ANN)-driven Genetic Algorithm(GA)methods for energy efficiency and economic performance optimization of energy efficiency measures in a multi-family house building in Greece.The energy efficiency measures include different heating/cooling systems(such as low-temperature and high-temperature heat pumps,natural gas boilers,split units),building envelope components for floor,walls,roof and windows of variable heat transfer coefficients,the installation of solar thermal collectors and PVs.The calculations of the building loads and investment and operating and maintenance costs of the measures are based on the methodology defined in Directive 2010/31/EU,while economic assumptions are based on EN 15459-1 standard.Typically,multi-objective optimization of energy efficiency measures often requires the simulation of very large numbers of cases involving numerous possible combinations,resulting in intense computational load.The results of the study indicate that ANN-driven GA methods can be used as an alternative,valuable tool for reliably predicting the optimal measures which minimize primary energy consumption and life cycle cost of the building with greatly reduced computational requirements.Through GA methods,the computational time needed for obtaining the optimal solutions is reduced by 96.4%-96.8%. 展开更多
关键词 energy efficiency measures gas boilerssplit units building envelope components energy efficiency economic performance artificial neural network ann driven multi objective optimization economic performance optimization ANN driven GA methods
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NEW STUDYING OF LATTICE BOLTZMANN METHOD FOR TWO-PHASE DRIVEN IN POROUS MEDIA 被引量:1
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作者 许友生 刘慈群 俞慧丹 《Applied Mathematics and Mechanics(English Edition)》 SCIE EI 2002年第4期387-393,共7页
By using the interaction of particles, such as the physical principle of the same attract each other and the different repulse each other, a new model of Lattice Boltzmann to simulate the two-phase driven in porous me... By using the interaction of particles, such as the physical principle of the same attract each other and the different repulse each other, a new model of Lattice Boltzmann to simulate the two-phase driven in porous media was discussed. The result shows effectively for the problem of two-phase driven in porous media. Furthermore, the method economizes on computer time, has less fluctuation on boundary surface and takes no average measure. 展开更多
关键词 porous medium two-phase driven method of lattice Boltzmann(LBM)
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Simulation of electrically driven jet using Chebyshev collocation method 被引量:1
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作者 Yan Liu Ruojing Zhang 《Theoretical & Applied Mechanics Letters》 CAS 2011年第3期18-22,共5页
The model of electrically driven jet is governed by a series of quasi 1D dimensionless partial differential equations(PDEs).Following the method of lines,the Chebyshev collocation method is employed to discretize the ... The model of electrically driven jet is governed by a series of quasi 1D dimensionless partial differential equations(PDEs).Following the method of lines,the Chebyshev collocation method is employed to discretize the PDEs and obtain a system of differential-algebraic equations(DAEs).By differentiating constrains in DAEs twice,the system is transformed into a set of ordinary differential equations(ODEs)with invariants.Then the implicit differential equations solver'ddaskr'is used to solve the ODEs and post-stabilization is executed at the end of each step.Results show the distributions of radius,linear charge density,stretching ratio and also the horizontal velocity at a time point.Meanwhile,the spiral and expanding projections to X-Y plane of the jet centerline suggest the occurring of bending instability. 展开更多
关键词 electrically driven jet method of lines Chebyshev collocation method differential-algebraic equation bending instability
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A semi-implicit three-step method based on SUPG finite element formulation for flow in lid driven cavities with different geometries 被引量:1
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作者 Cheng HUAN Dai ZHOU Yan BAO 《Journal of Zhejiang University-Science A(Applied Physics & Engineering)》 SCIE EI CAS CSCD 2011年第1期33-45,共13页
A numerical algorithm using a bilinear or linear finite element and semi-implicit three-step method is presented for the analysis of incompressible viscous fluid problems. The streamline upwind/Petrov-Galerkin (SUPG) ... A numerical algorithm using a bilinear or linear finite element and semi-implicit three-step method is presented for the analysis of incompressible viscous fluid problems. The streamline upwind/Petrov-Galerkin (SUPG) stabilization scheme is used for the formulation of the Navier-Stokes equations. For the spatial discretization, the convection term is treated explicitly, while the viscous term is treated implicitly, and for the temporal discretization, a three-step method is employed. The present method is applied to simulate the lid driven cavity problems with different geometries at low and high Reynolds numbers. The results compared with other numerical experiments are found to be feasible and satisfactory. 展开更多
关键词 Semi-implicit three-step method Streamline upwind/Petrov-Galerkin (SUPG) finite element method (FEM) Unsteady incompressible flows Lid driven cavity problem
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Multiscale topology optimization using feature-driven method 被引量:11
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作者 Zhao XU Weihong ZHANG +1 位作者 Ying ZHOU Jihong ZHU 《Chinese Journal of Aeronautics》 SCIE EI CAS CSCD 2020年第2期621-633,共13页
This paper presents a multiscale design method for simultaneous topology optimization of both macrostructures and microstructures.Geometric features are extended as design primitives at both macro and micro scales and... This paper presents a multiscale design method for simultaneous topology optimization of both macrostructures and microstructures.Geometric features are extended as design primitives at both macro and micro scales and represented by Level Set Functions(LSFs).Parameters related to the locations,sizes,and orientations of macro and micro features are considered as design variables and optimized simultaneously.In the overlapping areas of different macro features,embedded microstructures are optimally figured out as the solution of the corresponding sub-optimization,problem.In this study,the eXtended Finite Element Method(XFEM)is implemented for structural and sensitivity analyses with respect to design variables.This method has the advantage of using a fixed grid independent of the topology optimization process.The homogenization procedure is applied to calculate the effective properties of considered microstructures in each macro feature.Numerical examples are presented to illustrate the effectiveness of the proposed method.Results depict that the multiscale design cannot obviously improve structural stiffness compared with a solid-material design under the linear elastic condition. 展开更多
关键词 Feature-driven method Level SET function Multiscale design TOPOLOGY optimization XFEM
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Simulating high Reynolds number flow in two-dimensional lid-driven cavity by multi-relaxation-time lattice Boltzmann method 被引量:5
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作者 柴振华 施保昌 郑林 《Chinese Physics B》 SCIE EI CAS CSCD 2006年第8期1855-1863,共9页
By coupling the non-equilibrium extrapolation scheme for boundary condition with the multi-relaxation-time lattice Boltzmann method, this paper finds that the stability of the multi-relaxation-time model can be improv... By coupling the non-equilibrium extrapolation scheme for boundary condition with the multi-relaxation-time lattice Boltzmann method, this paper finds that the stability of the multi-relaxation-time model can be improved greatly, especially on simulating high Reynolds number (Re) flow. As a discovery, the super-stability analysed by Lallemand and Luo is verified and the complex structure of the cavity flow is also exhibited in our numerical simulation when Re is high enough. To the best knowledge of the authors, the maximum of Re which has been investigated by direct numerical simulation is only around 50 000 in the literature; however, this paper can readily extend the maximum to 1000 000 with the above combination. 展开更多
关键词 multi-relaxation-time lattice Boltzmann method non-equilibrium extrapolation scheme high Reynolds number lid-driven cavity flow
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Pore-scale study based on lattice Boltzmann method of density driven natural convection during CO_2 injection project
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作者 Abdelmalek Atia Kamal Mohammedi 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2015年第10期1593-1602,共10页
Saline aquifers are chosen for geological storage of greenhouse gas CO_2 because of their storage potential.In almost all cases of practical interest,CO_2 is present on top of the liquid and CO_2 dissolution leads to ... Saline aquifers are chosen for geological storage of greenhouse gas CO_2 because of their storage potential.In almost all cases of practical interest,CO_2 is present on top of the liquid and CO_2 dissolution leads to a small increase in the density of the aqueous phase.This situation results in the creation of negative buoyancy force for downward density-driven natural convection and consequently enhances CO_2 sequestration.In order to study CO_2 injection at pore-level,an isothermal Lattice Boltzmann Model(LBM) with two distribution functions is adopted to simulate density-driven natural convection in porous media with irregular geometry obtained by image treatment.The present analysis showed that after the onset of natural convection instability,the brine with a high CO_2 concentration infringed into the underlying unaffected brine,in favor of the migration of CO_2 into the pore structure.With low Rayleigh numbers,the instantaneous mass flux and total dissolved CO_2 mass are very close to that derived from penetration theory(diffusion only),but the fluxes are significantly enhanced with high Ra number.The simulated results show that as the time increases,some chaotic and recirculation zones in the flow appear obviously,which promotes the renewal of interfacial liquid,and hence enhances dissolution of CO_2 into brine.This study is focused on the scale of a few pores,but shows implications in enhanced oil/gas recovery with CO_2 sequestration in aquifers. 展开更多
关键词 Lattice Boltzmann method Density driven Pore-scale CO2 Mass transfer
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SUPG finite element method based on penalty function for lid-driven cavity flow up to Re = 27500 被引量:1
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作者 Da-Guo Wang Qing-Xiang Shui 《Acta Mechanica Sinica》 SCIE EI CAS CSCD 2016年第1期54-63,共10页
A streamline upwind/Petrov-Galerkin (SUPG) finite element method based on a penalty function is pro- posed for steady incompressible Navier-Stokes equations. The SUPG stabilization technique is employed for the for-... A streamline upwind/Petrov-Galerkin (SUPG) finite element method based on a penalty function is pro- posed for steady incompressible Navier-Stokes equations. The SUPG stabilization technique is employed for the for- mulation of momentum equations. Using the penalty function method, the continuity equation is simplified and the pres- sure of the momentum equations is eliminated. The lid-driven cavity flow problem is solved using the present model. It is shown that steady flow simulations are computable up to Re = 27500, and the present results agree well with previous solutions. Tabulated results for the properties of the primary vortex are also provided for benchmarking purposes. 展开更多
关键词 Streamline upwind/Petrov-Galerkin (SUPG)finite element method Lid-driven cavity flow Penaltyfunction method High Reynolds number
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A Data-Driven Adaptive Method for Attitude Control of Fixed-Wing Unmanned Aerial Vehicles 被引量:2
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作者 Meili Chen Yuan Wang 《Advances in Aerospace Science and Technology》 2019年第1期1-15,共15页
In this paper, a real-time online data-driven adaptive method is developed to deal with uncertainties such as high nonlinearity, strong coupling, parameter perturbation and external disturbances in attitude control of... In this paper, a real-time online data-driven adaptive method is developed to deal with uncertainties such as high nonlinearity, strong coupling, parameter perturbation and external disturbances in attitude control of fixed-wing unmanned aerial vehicles (UAVs). Firstly, a model-free adaptive control (MFAC) method requiring only input/output (I/O) data and no model information is adopted for control scheme design of angular velocity subsystem which contains all model information and up-mentioned uncertainties. Secondly, the internal model control (IMC) method featured with less tuning parameters and convenient tuning process is adopted for control scheme design of the certain Euler angle subsystem. Simulation results show that, the method developed is obviously superior to the cascade PID (CPID) method and the nonlinear dynamic inversion (NDI) method. 展开更多
关键词 DATA-driven Adaptive method ATTITUDE CONTROL Unmanned AERIAL Vehicles (UAV) Internal Model CONTROL
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A Novel Simulation Method for Power Electronics: Discrete State Event Driven Method
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作者 Boyang Li Zhengming Zhao +2 位作者 Yi Yang Yicheng Zhu Zhujun Yu 《CES Transactions on Electrical Machines and Systems》 2017年第3期273-282,共10页
In the analysis of power electronics system,it is necessary to simulate ordinary differential equations(ODEs)with discontinuities and stiffness.However,there are many difficulties in using traditional discrete-time al... In the analysis of power electronics system,it is necessary to simulate ordinary differential equations(ODEs)with discontinuities and stiffness.However,there are many difficulties in using traditional discrete-time algorithms to solve such equations.Kofman and others presented the quantized state systems(QSS)algorithm in the discrete event system specification(DEVS)formalism.The discretization is applied to the state variables instead of time range in QSS.QSS is efficient to solve ODEs,but it is difficulty to be used when simulating actual power electronics systems with controller’s and other events.Based on the idea of this numerical algorithm and discrete event,a Discrete State Event Driven(DSED)simulation method is presented in this paper,which is fit for simulation of power electronics system.The method is developed to deal with non-linearity,stiffness and multi-time scale of power electronics systems.The DSED simulation method includes event definition,module seperation and modeling,event-driven mechanisms,numerical computation based on QSS,and some other operations.Simulation results verified the effectiveness and validity of the proposed method. 展开更多
关键词 Discrete state event driven simulation method discontinuities and stiffness power electronics systems
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Iterative Case-Driven Method and Practice of Java Language Teaching
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作者 Guodong Xin Wei Wang +2 位作者 Junheng Huang Yang Liu Bailing Wang 《计算机教育》 2018年第12期36-40,共5页
This project intends to study and discuss the teaching method of programming languages through an iterative case-driven model, to break through the traditional syntax-based teaching method so that students can activel... This project intends to study and discuss the teaching method of programming languages through an iterative case-driven model, to break through the traditional syntax-based teaching method so that students can actively participate in the case analysis and design which are closely related to enterprise applications. The purpose of teaching is achieved through the gradual iterative case-driven model. This project can form the best practice for the iterative case teaching method and promote programming language course innovation. 展开更多
关键词 PROGRAMMING LANGUAGE TEACHING Java LANGUAGE TEACHING ITERATIVE case-driven TEACHING method
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Precision Microenvironment-Driven Isothermal Annealing for the Self-Assembly of Perpendicular Block Copolymers in High-Resolution Lithography Applications
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作者 Xiaotong Zhao Yuanlang Hou +11 位作者 Hanxiao Lu Sisi Chen Hui Bai Hanzhe Miao Yuanyuan Guan Sibo Fu Meng Su Xiangshun Geng Ming Lei Yi Yang Yanlin Song Tian-Ling Ren 《Chinese Physics Letters》 2025年第11期375-382,共8页
Block copolymer(BCP) nanolithography offers potential beyond traditional photolithographic limits, yet reliably producing low-defect, perpendicular domains remains challenging. We introduce a microenvironmentdriven is... Block copolymer(BCP) nanolithography offers potential beyond traditional photolithographic limits, yet reliably producing low-defect, perpendicular domains remains challenging. We introduce a microenvironmentdriven isothermal annealing method for directed self-assembly of BCP thin films. By annealing films at stable temperature in a quasi-sealed, inert-gas chamber, our approach promotes highly uniform perpendicular lamellar nanopatterns over large areas, effectively mitigating environmental fluctuations and emulating solvent-vapor annealing without solvent exposure. Resulting BCP structures demonstrate enhanced spatial coherence and notably low defect density. Furthermore, we successfully transfer these nanopatterns into precise metal nano-line arrays,confirming the method's capability for high-fidelity pattern replication. This scalable, solvent-free technique provides a robust, reliable route for high-resolution nanopatterning in advanced semiconductor manufacturing. 展开更多
关键词 photolithographic limits isothermal annealing method mitigating environmental fluctuations e block copolymer bcp annealing films high resolution lithography isothermal annealing microenvironment driven
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Adaptive Data-Driven Coordinated Control of UUVs for Maritime Search and Rescue
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作者 Hao-Liang Wang De-Zhi Yu +1 位作者 Li-Yu Lu Zhou-Hua Peng 《IEEE/CAA Journal of Automatica Sinica》 2025年第9期1953-1955,共3页
Dear Editor,This letter is concerned with a coordinated path following control method for multiple unmanned underwater vehicles(UUVs)to carry out maritime search and rescue(MSR)missions.The kinetic model parameters of... Dear Editor,This letter is concerned with a coordinated path following control method for multiple unmanned underwater vehicles(UUVs)to carry out maritime search and rescue(MSR)missions.The kinetic model parameters of each UUV is totally unknown.Firstly,a kinematic control law is constructed by designing a vertical line-of-sight(LOS)guidance scheme. 展开更多
关键词 data driven control coordinated path following control method coordinated control kinetic model parameters adaptive control unmanned underwater vehicles maritime search rescue unmanned underwater vehicles uuvs
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基于探究式自驱学习的有限元分析与应用研究生课程改革
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作者 黄海波 任潞 +2 位作者 束学道 梁丹 谢重阳 《高教学刊》 2026年第8期53-56,60,共5页
有限元方法是目前解决工程问题的重要手段,也成为工科专业学位研究生重要的专业修读课程。针对专业硕士研究生的扩招和培养目标侧重点的转变,宁波大学有限元分析与应用基于“OBE理念教学”和“探究式自驱型学习”的理念,开展一系列的教... 有限元方法是目前解决工程问题的重要手段,也成为工科专业学位研究生重要的专业修读课程。针对专业硕士研究生的扩招和培养目标侧重点的转变,宁波大学有限元分析与应用基于“OBE理念教学”和“探究式自驱型学习”的理念,开展一系列的教学改革与尝试。首先面向成果导向重新梳理课程目标,在简化介绍基本原理的基础上重点拓展知识边界并着重强调使用有限元工具处理等效、分析和解决问题的能力;设置团队合作项目,通过自驱式发现、分析和解决问题的探究型自主学习,使学生主动、积极地参与课程学习,提高教学质量。课程改革完全契合研究生课程设置的要求,改革成果可以为其他工科研究生专业课程的改革提供科学参考。 展开更多
关键词 有限元 OBE 探究式 自驱型 团队合作
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基于数据驱动的路网连续交通流短时预测方法综述
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作者 刘伟 钟灿 曹文明 《交通运输工程学报》 北大核心 2026年第2期24-43,共20页
为掌握数据驱动下的路网连续交通流短时预测技术发展最新动态,基于人工智能计算和实时交通数据采集技术快速发展的背景,对短时交通流深度学习预测模型、数据处理技术和预测效果进行了综述与总结。该研究梳理了交通流预测的经典统计模型... 为掌握数据驱动下的路网连续交通流短时预测技术发展最新动态,基于人工智能计算和实时交通数据采集技术快速发展的背景,对短时交通流深度学习预测模型、数据处理技术和预测效果进行了综述与总结。该研究梳理了交通流预测的经典统计模型、机器学习模型及深度学习模型的演变历程,重点分析了各类模型的优势与局限性;归纳了2024年至今的短时交通流预测方法研究进展,详细对比研究了循环神经网络、图卷积网络、多头注意力机制与Transformer架构、神经微分方程、超图理论及轻量化架构等短时交通流预测模型,以及联邦学习、迁移学习、生成对抗网络和多源数据融合等短时交通流预测数据处理技术;基于对均方根误差、平均绝对误差和平均绝对百分比误差三大核心指标的对比,总结了主流模型在标准化数据集PEMS上的性能,评估了代表性模型的泛化能力与稳定性。结果表明:深度学习方法相对于传统模型在短时交通流预测的精度、泛化能力及稳定性上具有明显优势;具备动态时空关系建模、多尺度周期数据结构、计算效率改进方法及增强鲁棒性机制等特征的短时交通流预测模型有更优异的性能;数据处理技术可有效改善数据隐私、跨区域差异、数据稀缺与异常缺失等实际问题,提升短时交通流预测模型的工程应用性能与可扩展性。未来可从时空特征挖掘、数据融合、模型轻量化、知识迁移以及模型工程应用等方面深化研究。 展开更多
关键词 交通工程 交通流 综述 短时预测方法 数据驱动 深度学习算法 数据处理技术
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数字警用集群(PDT)自动化测试中同步测量方法的研究
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作者 刘飞 邬鹏程 《计量与测试技术》 2026年第3期101-103,共3页
本文针对数字警用集群(PDT)自动化测试系统中的同步测量需求,研究了基于VISA的同步方法实现技术。在分析VISA同步原理的基础上,提出了三种VISA同步方式的实现方法,阐述了各自的实现原理,并根据系统不同需求场景设计相应的同步方法,解决... 本文针对数字警用集群(PDT)自动化测试系统中的同步测量需求,研究了基于VISA的同步方法实现技术。在分析VISA同步原理的基础上,提出了三种VISA同步方式的实现方法,阐述了各自的实现原理,并根据系统不同需求场景设计相应的同步方法,解决了系统对同步测量的迫切需求。研究表明,综合运用不同同步方法可显著提高系统稳定性与性能。 展开更多
关键词 同步方法 自动化测试 回调 事件驱动
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案例及任务驱动教学法在神经外科带教中的作用
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作者 刘伟 《中国卫生产业》 2026年第1期143-145,152,共4页
目的探究案例及任务驱动教学法在神经外科临床带教中的作用。方法选取2023年10月—2024年10月长春市中心医院42名神经外科实习生作为研究对象,按不同教学方法分为两组,各21名。对照组教学方法为传统教学法,研究组实施案例及任务驱动教学... 目的探究案例及任务驱动教学法在神经外科临床带教中的作用。方法选取2023年10月—2024年10月长春市中心医院42名神经外科实习生作为研究对象,按不同教学方法分为两组,各21名。对照组教学方法为传统教学法,研究组实施案例及任务驱动教学法,比较两组考核成绩、教学满意度、教学质量。结果研究组理论知识评分为(91.53±5.62)分,病例分析评分为(93.97±4.73)分,临床操作评分为(92.76±4.07)分,均高于对照组的(87.31±7.23)分、(86.14±8.02)分、(85.82±6.15)分,差异均有统计学意义(t=2.112,3.854,4.312;P均<0.05)。研究组教学满意度高于对照组,差异有统计学意义(P<0.05)。研究组各项教学质量得分高于对照组,差异均有统计学意义(P均<0.05)。结论案例及任务驱动教学法在神经外科临床带教中既能够提高教学质量、考核成绩,也可提高教学满意度。 展开更多
关键词 案例教学法 任务驱动教学法 神经外科 教学质量 考核成绩
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基于卷积神经网络的数据中心气流温度场快速预测
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作者 任波 贺伟 +3 位作者 罗惠恒 刘育策 王梦 章文恺 《邮电设计技术》 2026年第3期74-79,共6页
为实现数据中心制冷系统精细化节能,针对传统CFD计算耗时及现有模型空间利用不足的问题,提出一种基于卷积神经网络的气流温度场预测框架。该方法通过空间特征图构建输入空间特征,利用卷积神经网络对空间特征进行提取、编码,使用人工神... 为实现数据中心制冷系统精细化节能,针对传统CFD计算耗时及现有模型空间利用不足的问题,提出一种基于卷积神经网络的气流温度场预测框架。该方法通过空间特征图构建输入空间特征,利用卷积神经网络对空间特征进行提取、编码,使用人工神经网络融合工况信息与空间信息,并通过反卷积神经网络实现快速预测。经某大型数据中心机房的温度场数据验证,该方法平均绝对误差为0.312℃,可以为数据中心机房的精细化节能控制提供更可靠的气流组织。 展开更多
关键词 数据中心 气流组织 数据驱动模型 卷积神经网络 人工神经网络
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有水气藏水侵特征分析方法现状及未来发展方向
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作者 李晓平 彭港珍 +5 位作者 谭晓华 权芳 邓永建 周潇君 韩晓冰 卿太雄 《天然气勘探与开发》 2026年第1期40-50,共11页
有水气藏在开发过程中有可能因水侵导致气井产能下降,甚至水淹停产而使得气藏采收率大幅降低。为了给后续研究和工程应用提供参考,系统梳理了现有水侵特征分析方法的现状与研究进展,采用文献分析与技术对比的方法,重点评述了水化学分析... 有水气藏在开发过程中有可能因水侵导致气井产能下降,甚至水淹停产而使得气藏采收率大幅降低。为了给后续研究和工程应用提供参考,系统梳理了现有水侵特征分析方法的现状与研究进展,采用文献分析与技术对比的方法,重点评述了水化学分析、生产动态判别、压力响应、开发测井与测试技术以及数据驱动等方法在水侵类型识别、水体活跃程度评价、水侵路径追踪等方面的适用性与局限性。研究结果表明:(1)水化学分析方法可有效区分不同水源类型,但响应滞后;(2)生产动态分析方法虽简便直观,但却难以定量表征水侵强度;(3)压力响应类方法能够动态监测水侵过程并定量评估其影响,但部分模型尚未充分考虑水封气等机制;(4)开发测井与测试技术具有高分辨率和较强针对性,但实施成本较高;(5)数据驱动方法在产水趋势预测方面展现出良好潜力,但其性能高度依赖于数据质量与算力支撑。结论认为,单一的水侵特征分析方法都存在着局限性,实际应用中需融合多种方法以提升水侵识别与评价的综合精度与可靠性,未来应构建兼顾物理约束与数据驱动的水侵早期预警体系,进而实现从滞后响应向早期主动防控的转变。 展开更多
关键词 有水气藏 水侵特征 水化学 生产动态 压力响应 开发测井与测试技术 数据驱动
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罗非鱼肌原纤维蛋白/卡拉胶寡糖纳米复合物构建及其对姜黄素的控释性能
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作者 邱玉贞 李瑞 +4 位作者 赵巧丽 汪卓 刘晓菲 宋兵兵 钟赛意 《食品科学》 北大核心 2026年第6期12-22,共11页
本研究采用pH值驱动法,构建罗非鱼肌原纤维蛋白(tilapia myofibrillar protein,TMP)/κ-卡拉胶寡糖(κ-carrageenan oligosaccharide,κCOS)纳米复合物,并对姜黄素(curcumin,CUR)进行包载,以解决CUR低生物利用度和性质不稳定性的问题。... 本研究采用pH值驱动法,构建罗非鱼肌原纤维蛋白(tilapia myofibrillar protein,TMP)/κ-卡拉胶寡糖(κ-carrageenan oligosaccharide,κCOS)纳米复合物,并对姜黄素(curcumin,CUR)进行包载,以解决CUR低生物利用度和性质不稳定性的问题。该纳米复合物在其在最佳质量浓度条件下(TMP 12 mg/mL、κCOS 4 mg/mL)制备的纳米复合物粒径为(291.16±5.37)nm,Zeta电位为(-29.80±1.67)mV,多分散系数为0.34±0.04。TMP/κCOS纳米复合物形成了三维网状结构;当CUR在纳米复合物中质量浓度达到2 mg/mL时,可有效包载于纳米复合物中,且获得较高的包载率((76.76±0.04)%)。红外光谱和圆二色光谱结果表明,TMP与κCOS通过静电作用和疏水相互作用结合,且结合后α-螺旋含量显著增加,由22%(TMP)增加至76%(TMP/κCOS)。体外释放结果表明,TMP/κCOS/CUR复合物在60 min时的CUR释放率仅为(14.43±0.85)%,在180 min时的CUR释放率可达(74.71±0.70)%。该纳米复合物可有效提高CUR的离子稳定性及热稳定性。本研究可为TMP/κCOS纳米递送系统的构建提供可靠工艺,也表明其在疏水性活性成分递送领域具有良好应用潜力。 展开更多
关键词 纳米复合物 肌原纤维蛋白 κ-卡拉胶寡糖 姜黄素 pH值驱动
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