In the context of large language model(LLM)reshaping software engineering education,this paper presents OSSerCopilot,a LLM-based tutoring system designed to address the critical challenge faced by newcomers(especially...In the context of large language model(LLM)reshaping software engineering education,this paper presents OSSerCopilot,a LLM-based tutoring system designed to address the critical challenge faced by newcomers(especially student contributors)in open source software(OSS)communities.Leveraging natural language processing,code semantic understanding,and learner profiling,the system functions as an intelligent tutor to scaffold three core competency domains:contribution guideline interpretation,project architecture comprehension,and personalized task matching.By transforming traditional onboarding barriers-such as complex contribution documentation and opaque project structures-into interactive learning journeys,OSSerCopilot enables newcomers to complete their first OSS contribution more easily and confidently.This paper highlights how LLM technologies can redefine software engineering education by bridging the gap between theoretical knowledge and practical OSS participation,offering implications for curriculum design,competency assessment,and sustainable OSS ecosystem cultivation.A demonstration video of the system is available at https://figshare.com/articles/media/OSSerCopilot_Introduction_mp4/29510276.展开更多
Introduction-Nuclei near and beyond the proton drip line represent a fascinating frontier in the nuclear landscape. Proton-rich nuclei exhibit intriguing phenomena, such as the Thomas-Ehrman shift and proton-halo stru...Introduction-Nuclei near and beyond the proton drip line represent a fascinating frontier in the nuclear landscape. Proton-rich nuclei exhibit intriguing phenomena, such as the Thomas-Ehrman shift and proton-halo structure. Beyond the proton dripline, nuclei become unbound, allowing protons to be emitted and giving rise to novel radioactive decay modes. Single-proton radioactivity, a process in which some nuclei with an odd number of protons(Z) decay by ejecting a proton, was discovered several decades ago and has been extensively studied [1, 2].展开更多
Dear Editor,This letter studies a real-world issue in leader-follower multi-agent systems(MASs)named open topology,which permits the variations of agent set and network connections.Specially,a novel transition process...Dear Editor,This letter studies a real-world issue in leader-follower multi-agent systems(MASs)named open topology,which permits the variations of agent set and network connections.Specially,a novel transition process is developed to explain how the involved variation of network scale affects the dynamic behavior of the MASs.From a resource limited perspective,the distributed saturated impulsive control is then designed,under which some sufficient criteria are integrated into local quasi-consensus performance.We also provide a combined optimization algorithm for all agents to make the estimated domain of initial errors closer to the real one,thereby resulting in less conservativeness.Finally,a numerical example validates our results.展开更多
High catalytic efficiencies in ring opening polymerization(ROP)of a large ring-sized macrolactone,ω-pentadecalactone(PDL),by using transition metal Fe(II)-based catalysts were achieved for the first time in this stud...High catalytic efficiencies in ring opening polymerization(ROP)of a large ring-sized macrolactone,ω-pentadecalactone(PDL),by using transition metal Fe(II)-based catalysts were achieved for the first time in this study.Benefited from the bulky nature of the ligatedα-diimine ligands,as evidenced from single-crystal structures,as well as the weakly oxophilic nature of the metal centers,chain transesterification reactions could be partially suppressed,allowing the polymerization proceed in a living-like and semi-controllable manner,i.e.good linear dependence of propagation rates on catalyst concentration and PDL concentration as observed in the detailed kinetics studies.The whole polymerization proceeds via a“coordination-insertion”mechanism,and with the aid of density functional theory(DFT)calculation studies,a“slow insertion→fast elimination”manner was demonstrated for the monomer propagation step,suggesting the insertion of Fe-OR into the carbonyl group C=O as the rate-determining step.The present catalytic system also showed fast chain transfer reactions to alcohol compounds,affording quasi-immortal characteristics.DFT calculations showed that such a transfer reaction only required an energy barrier of 6.4 kcal/mol,performing a good consistency with the fast chain transfer rates.展开更多
BACKGROUND Descending thoracic aortic aneurysms are dangerous and have to be treated quickly.The primary treatment methods are thoracic endovascular aortic repair(TEVAR)and open surgical repair(OSR).The comparative ef...BACKGROUND Descending thoracic aortic aneurysms are dangerous and have to be treated quickly.The primary treatment methods are thoracic endovascular aortic repair(TEVAR)and open surgical repair(OSR).The comparative effectiveness and safety of TEVAR and OSR were evaluated in this meta-analysis,focusing on perioperative and long-term outcomes.AIM To compare and contrast the efficacy and safety of TEVAR vs OSR in the treatment of descending thoracic aortic aneurysms.This study aims to assess both perioperative and long-term outcomes through a systematic review and metaanalysis.METHODS A comprehensive search of PubMed,EMBASE,and Cochrane was conducted from inception to January 2025.Baseline characteristics and outcomes were evaluated.Odds ratios(OR)for dichotomous data and mean differences for continuous data with 95%confidence intervals(CI)were analyzed using random-effects models.RESULTS A meta-analysis of 21 studies involving 29465 patients(8261 TEVAR;21204 OR)showed TEVAR associated with lower operative mortality(OR=0.60,95%CI:0.42-0.85,P=0.004),shorter intensive care unit(-2.94 days,95%CI:-4.76 to-1.12,P=0.002)and hospital stays(-7.35 days,95%CI:-10.54 to-4.17,P<0.00001),and reduced rates of paraplegia(OR=0.44,95%CI:0.27-0.73,P=0.002),spinal ischemia(OR=0.30,95%CI:0.16-0.56,P=0.0002),renal failure(OR=0.29,95%CI:0.14-0.61,P=0.001),and wound infections(OR=0.28,95%CI:0.13-0.61,P=0.001).However,TEVAR had higher rates of vascular complications.No significant differences were noted in 1-year and 5-year mortality rates,the rate of non-elective surgery,neurological complications,or stroke rates.CONCLUSION Compared to EVAR,TEVAR revealed lower operative mortality and better perioperative outcomes across all indicators,including hospital and intensive care unit stays,as well as fewer complications,except for those related to vascular problems.Mortality results were also similar in the long run;consequently,more research is required concerning the long-term durability.展开更多
China’s commitment to high-standard opening-up during its 15th Five-Year Plan period offers Europe an alternative approach to economic resilience.IN medical practice,a wise doctor does not treat a fever by plunging t...China’s commitment to high-standard opening-up during its 15th Five-Year Plan period offers Europe an alternative approach to economic resilience.IN medical practice,a wise doctor does not treat a fever by plunging the patient into an ice bath.The sudden shock may lower the temperature,but it risks systemic collapse.Instead,the proper treatment should support the body’s own resilience,combat the infection.展开更多
When China announced that it would “seal customs operations” in Hainan,the phrase travelled poorly beyond its borders. To many foreign readers, the term sounds defensive, even restrictive—as if an island were being...When China announced that it would “seal customs operations” in Hainan,the phrase travelled poorly beyond its borders. To many foreign readers, the term sounds defensive, even restrictive—as if an island were being closed off at a time when the global economy urgently needs openness.From Southeast Asia, however, the policy looks less like retreat and more like revelation.It shines light on how China’s understanding of openness has evolved—shaped not by slogans, but by the trade frictions of recent years. What is unfolding in Hainan is not an attempt to close an island, but an effort to define,with unusual precision, where openness begins and how it is sustained.展开更多
Hainan Province in south China is the country’s second-largest island and the largest free trade port by area.It has entered a historic phase in China’s drive to promote high-level institutional opening up.On 18 Dec...Hainan Province in south China is the country’s second-largest island and the largest free trade port by area.It has entered a historic phase in China’s drive to promote high-level institutional opening up.On 18 December 2025,Hainan officially launched island-wide special customs operations,commonly referred to as“customs closure.”From that date,goods entering or leaving the island,except those traded with the Chinese mainland,are subject to simplified customs procedures and potentially reduced or zero tariffs.展开更多
Metok,located in Nyingchi,the Xizang Autonomous Region,is known as the last county in China to be connected by road.Poor transportation and limited access to petroleum were two obstacles to its development.As soon as ...Metok,located in Nyingchi,the Xizang Autonomous Region,is known as the last county in China to be connected by road.Poor transportation and limited access to petroleum were two obstacles to its development.As soon as the highway connecting Metok and the outside world was completed in 2014,China National Petroleum Corporation’s(CNPC)first gas station in the county was put into operation,providing the momentum for this"secret land of Lotus"and helping it embark on a journey toward openness and prosperity.展开更多
Local residents,artists,and entrepreneurs who converge on Haikou’s historical Qilou Street are contributing to a new chapter in the story of Hainan’s opening-up.MORE than 100 years ago,the area alongQilou(Sotto Port...Local residents,artists,and entrepreneurs who converge on Haikou’s historical Qilou Street are contributing to a new chapter in the story of Hainan’s opening-up.MORE than 100 years ago,the area alongQilou(Sotto Portico)Street in Haikou,capital of Hainan Province,served asthe embarkation point for Hainanesesetting out on their maritime voyages to seek greener pastures.展开更多
AIM:To evaluate the clinical characteristics and risk factors associated with visual prognosis in patients with open globe injuries(OGIs)treated at Vietnam National Eye Hospital.METHODS:A prospective observational stu...AIM:To evaluate the clinical characteristics and risk factors associated with visual prognosis in patients with open globe injuries(OGIs)treated at Vietnam National Eye Hospital.METHODS:A prospective observational study included patients with OGIs treated between June 2023 and June 2024.Data on demographics,injury features,and clinical findings were extracted from medical records.Poor visual outcome was defined as final best-corrected visual acuity(BCVA)worse than 20/400 or no light perception.Multivariable logistic regression was performed to identify independent risk factors.RESULTS:Among 509 patients(636 eyes),the mean age was 35.13y(range 20–51y),and 67.6%were male.After treatment,the proportion of eyes achieving≥20/40 increased from 12.6%to 42.1%,while no light perception decreased from 29.1%to 9.4%.Independent predictors of poor visual outcomes included delayed admission[>4h,odds ratio(OR)=3.33,95%confidence intervals(CI):1.76–6.33,P<0.001],Zone III injury(OR=5.90,95%CI:2.85–12.24,P<0.001),wound length>10 mm(OR=2.59,95%CI:1.60–4.18,P<0.001),relative afferent pupillary defect(RAPD,OR=1.65,95%CI:1.03–2.64,P=0.039),endophthalmitis(OR=1.75,95%CI:1.01–3.03,P=0.047),retinal detachment(OR=3.32,95%CI:2.02–5.45,P<0.001),and eyelid lacerations(OR=1.94,95%CI:1.13–3.33,P=0.016)associated with OGIs.Vitreous hemorrhage(OR=0.44,95%CI:0.22–0.89,P=0.023)was associated with better outcomes,and female gender appeared protective.CONCLUSION:Poor visual outcomes remain common after OGIs,despite improve visual acuity in many cases.Several clinical and injury-related factors are strongly associated with prognosis.Early recognition of these predictors can support risk stratification and improve trauma care in similar settings.展开更多
China’s commitment to high-standard opening-upduring its 15th Five-Year Plan period offers Europe analternative approach to economic resilience.AT a time when much of the Westernworld is retreating behind tariff wall...China’s commitment to high-standard opening-upduring its 15th Five-Year Plan period offers Europe analternative approach to economic resilience.AT a time when much of the Westernworld is retreating behind tariff wallsand industrial policy rhetoric framedaround“unfair competition,”China ismoving steadfastly in the opposite direction.展开更多
At present, enhancing the digital literacy of village cadres faces practical constraints such as governance capability gaps induced by the second-level digital divide, the absence of a systematic cultivation system, i...At present, enhancing the digital literacy of village cadres faces practical constraints such as governance capability gaps induced by the second-level digital divide, the absence of a systematic cultivation system, incomplete last-kilometer implementation for translating skills into practice, and inadequate incentive mechanisms. As a novel educational form deeply integrating digital information technology with teaching and learning, distance open education provides multi-directional empowerment for enhancing village cadres digital literacy. This is achieved through open learning methods, the application of modern digital technologies, tailored learning programs, and the establishment of "overpass bridges" for translating learning outcomes into practice. Based on this, it is essential to further streamline the pathways for educating and cultivating village cadres, vigorously promote the digitalization of teaching, practice, and support services, develop systematic and localized digital education resources, and actively explore and establish a complementary credit bank system for their digital literacy cultivation.展开更多
在5G与数字生态融合背景下,GSMA Open Gateway通过标准化API与统一接入框架,实现应用在全球运营商网络的可移植与规模化部署,降低开发与适配成本,推动运营商能力开放。然而,跨运营商能力调用仍是关键瓶颈。因此,梳理了CAMARA 4类应用程...在5G与数字生态融合背景下,GSMA Open Gateway通过标准化API与统一接入框架,实现应用在全球运营商网络的可移植与规模化部署,降低开发与适配成本,推动运营商能力开放。然而,跨运营商能力调用仍是关键瓶颈。因此,梳理了CAMARA 4类应用程序编程接口(API)分发模式,对比分析了国内外实践差异。其中,国内运营商针对国内5G网络按需质量保障(QoD)3网互通中聚合平台(Aggregator)面临的痛点,提出了以软件开发工具包(SDK)为核心的解决方案。这一方案通过了统一认证和中国香港商用案例的可行性验证。此外,我国还提出了“SDK+Open Gateway”全球推广与模型上下文协议(MCP)模式演进路径,为全球运营商跨网协同提供中国经验,推动生态从技术框架迈向规模商用,助力数字经济高质量发展。展开更多
The Hainan Free Trade Port (FTP) is a key step for China to advance high-standard opening-up and seize a more active role in economic globalization. After early trials, a policy framework has taken shape, and islandwi...The Hainan Free Trade Port (FTP) is a key step for China to advance high-standard opening-up and seize a more active role in economic globalization. After early trials, a policy framework has taken shape, and islandwide special customs operations mark a shift from design to full implementation.As of January 18, island-wide special customs operations in Hainan FTP had been in place for a month. The first month ran smoothly, with more efficient flow of goods, people, and capital.This reflects China’s institutional opening-up and, amid slowing global growth, has injected fresh vitality into the regional and global economy.展开更多
Objective:Robotic-assisted living donor nephrectomy(RALDN)has been shown to be a safe and feasible option,offering enhanced visualization and improved surgical dexterity,allowing for a potential increase in the living...Objective:Robotic-assisted living donor nephrectomy(RALDN)has been shown to be a safe and feasible option,offering enhanced visualization and improved surgical dexterity,allowing for a potential increase in the living donor pool to perform pediatric and adult kidney transplants,even in cases of grafts with anatomical variants.We report our recent experience in using RALDN for open kidney transplantation(OKT).Methods:Between August 2021 and July 2025,122 kidney transplant recipients underwent OKT using RALDN grafts obtained at the Miami Transplant Institute.Clinical outcomes,during the first12 months post-transplant,including the incidence of delayed graft function(DGF),surgical complications,estimated glomerular filtrationrate(eGFR),and graft loss,were evaluated.Results:Sixteen pediatric and 106 adult recipients were included.The median recipient and donor ages were 42.2 yr and 39.5 yr,respectively.Male recipients comprised 63.1%(77/122);female donors comprised 56.6%(69/122).Among the donors,no conversion to open surgery was needed,and no postoperative complications attributed to the RALDN procedure were observed.Thirty-one kidney grafts required back table reconstruction.The median cold and warm ischemia times were 55.5 min and 27.0 min,respectively.One case(0.8%)of DGF was observed.One recipient(0.8%)developed a postoperative vascular complication;five(4.1%)developed a urologic complication.The median eGFRs at 1 mo,3 mo,6 mo,and 12 mo post-transplant were 71.9,77.1,75.1,and 72.1 mL/min/1.73 m2,respectively.No cases of graft failure during the first12 months post-transplant were observed,and one patient died with a functioning graft.Conclusion:RALDN is a safe and effective technique that provides favorable outcomes among both donors and recipients.This minimally invasive approach should be offered as a safe alternative to living donor patients.展开更多
On December 18,2025, Hainan Free Trade Port (Hainan FTP) officially began islandwide special customs operations.Although only two months have passed since this landmark step, the shift is already visible everywhere—f...On December 18,2025, Hainan Free Trade Port (Hainan FTP) officially began islandwide special customs operations.Although only two months have passed since this landmark step, the shift is already visible everywhere—from the bustling flow of international passengers at Haikou Meilan International Airport to the steady stream of cargo vessels calling at Yangpu Port, and even in the sustained attention investors are paying to “Hainan-related” stocks.Together, these signals point to one clear conclusion:China’s largest special economic zone has entered a new phase of development.展开更多
AIM:To study the relationships between amplitude of low-frequency fluctuations(ALFF)changes and clinical ophthalmic parameters in patients with primary open angle glaucoma(POAG)and analyze the diagnostic value of ALFF...AIM:To study the relationships between amplitude of low-frequency fluctuations(ALFF)changes and clinical ophthalmic parameters in patients with primary open angle glaucoma(POAG)and analyze the diagnostic value of ALFF.METHODS:Twenty-four POAG patients and 24 healthy controls(HCs)underwent resting-state functional magnetic resonance imaging(rs-fMRI).Nonparametric rank-sum tests were used to compare the ALFF values in the slow-4 and slow-5 bands,and Spearman or Pearson correlation analysis was used to assess the correlation between ALFF changes and clinical ophthalmic parameters in POAG patients.Receiver operating characteristic(ROC)curves were used to evaluate the diagnostic performance of the ALFF.RESULTS:There were 16 males in POAG patients(median age 48y)and 12 males in HCs(median age 39y).Compared with HCs,POAG patients presented increased or decreased ALFF values in different brain regions,and similar changes were observed in mild POAG patients.The ALFF values were correlated with retinal nerve fiber layer(RNFL)thickness,inner limiting membrane-retinal pigment epithelium thickness changes and the degree of visual field defects.Analysis of the diagnostic value of the ALFF via ROC curves revealed that the right medial frontal gyrus[area under the curve(AUC)=0.9063]and superior frontal gyrus(AUC=0.9097)had better diagnostic value than did the optic disc area(AUC=0.8019),visual field index(VFI%,AUC=0.8988)and macular parameters.CONCLUSION:POAG patients present altered cortical function that is significantly correlated with the optic nerve and retinal thickness and had good diagnostic value,which may reflect the underlying neuropathological mechanism of POAG.展开更多
基金supported by the National Natural Science Foundation of China (62202022, 92582204, and 62572030)the Fundamental Research Funds for the Central Universitiesthe exploratory elective projects of the State Key Laboratory of Complex and Critical Software Environments
文摘In the context of large language model(LLM)reshaping software engineering education,this paper presents OSSerCopilot,a LLM-based tutoring system designed to address the critical challenge faced by newcomers(especially student contributors)in open source software(OSS)communities.Leveraging natural language processing,code semantic understanding,and learner profiling,the system functions as an intelligent tutor to scaffold three core competency domains:contribution guideline interpretation,project architecture comprehension,and personalized task matching.By transforming traditional onboarding barriers-such as complex contribution documentation and opaque project structures-into interactive learning journeys,OSSerCopilot enables newcomers to complete their first OSS contribution more easily and confidently.This paper highlights how LLM technologies can redefine software engineering education by bridging the gap between theoretical knowledge and practical OSS participation,offering implications for curriculum design,competency assessment,and sustainable OSS ecosystem cultivation.A demonstration video of the system is available at https://figshare.com/articles/media/OSSerCopilot_Introduction_mp4/29510276.
文摘Introduction-Nuclei near and beyond the proton drip line represent a fascinating frontier in the nuclear landscape. Proton-rich nuclei exhibit intriguing phenomena, such as the Thomas-Ehrman shift and proton-halo structure. Beyond the proton dripline, nuclei become unbound, allowing protons to be emitted and giving rise to novel radioactive decay modes. Single-proton radioactivity, a process in which some nuclei with an odd number of protons(Z) decay by ejecting a proton, was discovered several decades ago and has been extensively studied [1, 2].
基金supported by the Natural Science Foundation of Jiangsu Province(BK20240009)the National Natural Science Foundation of China(62373105,62373262)Jiangsu Provincial Scientific Research Center of Applied Mathematics(BK20233002).
文摘Dear Editor,This letter studies a real-world issue in leader-follower multi-agent systems(MASs)named open topology,which permits the variations of agent set and network connections.Specially,a novel transition process is developed to explain how the involved variation of network scale affects the dynamic behavior of the MASs.From a resource limited perspective,the distributed saturated impulsive control is then designed,under which some sufficient criteria are integrated into local quasi-consensus performance.We also provide a combined optimization algorithm for all agents to make the estimated domain of initial errors closer to the real one,thereby resulting in less conservativeness.Finally,a numerical example validates our results.
基金financially supported by the National Natural Science Foundation of China(Nos.21901020 and 22003076)China Postdoctoral Science Foundation(No.2021M701818)+1 种基金Shandong Provincial Natural Science Foundation(No.ZR2022QE237)the Qingdao Postdoctoral Applied Research Project.H.Liu sincerely acknowledges financial support from the Taishan Scholars Program(No.tsqn202211165)。
文摘High catalytic efficiencies in ring opening polymerization(ROP)of a large ring-sized macrolactone,ω-pentadecalactone(PDL),by using transition metal Fe(II)-based catalysts were achieved for the first time in this study.Benefited from the bulky nature of the ligatedα-diimine ligands,as evidenced from single-crystal structures,as well as the weakly oxophilic nature of the metal centers,chain transesterification reactions could be partially suppressed,allowing the polymerization proceed in a living-like and semi-controllable manner,i.e.good linear dependence of propagation rates on catalyst concentration and PDL concentration as observed in the detailed kinetics studies.The whole polymerization proceeds via a“coordination-insertion”mechanism,and with the aid of density functional theory(DFT)calculation studies,a“slow insertion→fast elimination”manner was demonstrated for the monomer propagation step,suggesting the insertion of Fe-OR into the carbonyl group C=O as the rate-determining step.The present catalytic system also showed fast chain transfer reactions to alcohol compounds,affording quasi-immortal characteristics.DFT calculations showed that such a transfer reaction only required an energy barrier of 6.4 kcal/mol,performing a good consistency with the fast chain transfer rates.
文摘BACKGROUND Descending thoracic aortic aneurysms are dangerous and have to be treated quickly.The primary treatment methods are thoracic endovascular aortic repair(TEVAR)and open surgical repair(OSR).The comparative effectiveness and safety of TEVAR and OSR were evaluated in this meta-analysis,focusing on perioperative and long-term outcomes.AIM To compare and contrast the efficacy and safety of TEVAR vs OSR in the treatment of descending thoracic aortic aneurysms.This study aims to assess both perioperative and long-term outcomes through a systematic review and metaanalysis.METHODS A comprehensive search of PubMed,EMBASE,and Cochrane was conducted from inception to January 2025.Baseline characteristics and outcomes were evaluated.Odds ratios(OR)for dichotomous data and mean differences for continuous data with 95%confidence intervals(CI)were analyzed using random-effects models.RESULTS A meta-analysis of 21 studies involving 29465 patients(8261 TEVAR;21204 OR)showed TEVAR associated with lower operative mortality(OR=0.60,95%CI:0.42-0.85,P=0.004),shorter intensive care unit(-2.94 days,95%CI:-4.76 to-1.12,P=0.002)and hospital stays(-7.35 days,95%CI:-10.54 to-4.17,P<0.00001),and reduced rates of paraplegia(OR=0.44,95%CI:0.27-0.73,P=0.002),spinal ischemia(OR=0.30,95%CI:0.16-0.56,P=0.0002),renal failure(OR=0.29,95%CI:0.14-0.61,P=0.001),and wound infections(OR=0.28,95%CI:0.13-0.61,P=0.001).However,TEVAR had higher rates of vascular complications.No significant differences were noted in 1-year and 5-year mortality rates,the rate of non-elective surgery,neurological complications,or stroke rates.CONCLUSION Compared to EVAR,TEVAR revealed lower operative mortality and better perioperative outcomes across all indicators,including hospital and intensive care unit stays,as well as fewer complications,except for those related to vascular problems.Mortality results were also similar in the long run;consequently,more research is required concerning the long-term durability.
文摘China’s commitment to high-standard opening-up during its 15th Five-Year Plan period offers Europe an alternative approach to economic resilience.IN medical practice,a wise doctor does not treat a fever by plunging the patient into an ice bath.The sudden shock may lower the temperature,but it risks systemic collapse.Instead,the proper treatment should support the body’s own resilience,combat the infection.
文摘When China announced that it would “seal customs operations” in Hainan,the phrase travelled poorly beyond its borders. To many foreign readers, the term sounds defensive, even restrictive—as if an island were being closed off at a time when the global economy urgently needs openness.From Southeast Asia, however, the policy looks less like retreat and more like revelation.It shines light on how China’s understanding of openness has evolved—shaped not by slogans, but by the trade frictions of recent years. What is unfolding in Hainan is not an attempt to close an island, but an effort to define,with unusual precision, where openness begins and how it is sustained.
文摘Hainan Province in south China is the country’s second-largest island and the largest free trade port by area.It has entered a historic phase in China’s drive to promote high-level institutional opening up.On 18 December 2025,Hainan officially launched island-wide special customs operations,commonly referred to as“customs closure.”From that date,goods entering or leaving the island,except those traded with the Chinese mainland,are subject to simplified customs procedures and potentially reduced or zero tariffs.
文摘Metok,located in Nyingchi,the Xizang Autonomous Region,is known as the last county in China to be connected by road.Poor transportation and limited access to petroleum were two obstacles to its development.As soon as the highway connecting Metok and the outside world was completed in 2014,China National Petroleum Corporation’s(CNPC)first gas station in the county was put into operation,providing the momentum for this"secret land of Lotus"and helping it embark on a journey toward openness and prosperity.
文摘Local residents,artists,and entrepreneurs who converge on Haikou’s historical Qilou Street are contributing to a new chapter in the story of Hainan’s opening-up.MORE than 100 years ago,the area alongQilou(Sotto Portico)Street in Haikou,capital of Hainan Province,served asthe embarkation point for Hainanesesetting out on their maritime voyages to seek greener pastures.
文摘AIM:To evaluate the clinical characteristics and risk factors associated with visual prognosis in patients with open globe injuries(OGIs)treated at Vietnam National Eye Hospital.METHODS:A prospective observational study included patients with OGIs treated between June 2023 and June 2024.Data on demographics,injury features,and clinical findings were extracted from medical records.Poor visual outcome was defined as final best-corrected visual acuity(BCVA)worse than 20/400 or no light perception.Multivariable logistic regression was performed to identify independent risk factors.RESULTS:Among 509 patients(636 eyes),the mean age was 35.13y(range 20–51y),and 67.6%were male.After treatment,the proportion of eyes achieving≥20/40 increased from 12.6%to 42.1%,while no light perception decreased from 29.1%to 9.4%.Independent predictors of poor visual outcomes included delayed admission[>4h,odds ratio(OR)=3.33,95%confidence intervals(CI):1.76–6.33,P<0.001],Zone III injury(OR=5.90,95%CI:2.85–12.24,P<0.001),wound length>10 mm(OR=2.59,95%CI:1.60–4.18,P<0.001),relative afferent pupillary defect(RAPD,OR=1.65,95%CI:1.03–2.64,P=0.039),endophthalmitis(OR=1.75,95%CI:1.01–3.03,P=0.047),retinal detachment(OR=3.32,95%CI:2.02–5.45,P<0.001),and eyelid lacerations(OR=1.94,95%CI:1.13–3.33,P=0.016)associated with OGIs.Vitreous hemorrhage(OR=0.44,95%CI:0.22–0.89,P=0.023)was associated with better outcomes,and female gender appeared protective.CONCLUSION:Poor visual outcomes remain common after OGIs,despite improve visual acuity in many cases.Several clinical and injury-related factors are strongly associated with prognosis.Early recognition of these predictors can support risk stratification and improve trauma care in similar settings.
文摘China’s commitment to high-standard opening-upduring its 15th Five-Year Plan period offers Europe analternative approach to economic resilience.AT a time when much of the Westernworld is retreating behind tariff wallsand industrial policy rhetoric framedaround“unfair competition,”China ismoving steadfastly in the opposite direction.
基金Supported by Science Research Fund Project of Yunnan Provincial Department of Education-Research on the Pathways for Distance Open Education to Empower the Enhancement of Digital Literacy and Skills of Rural"Leading Geese"in Ethnic Areas(2023J0792)The Ideological and Political Education Reform Project of Yunnan Province in 2022-Exploration and Practice of Integrating Ideological and Political Education into the Training Mode of"Leading Goose"Talents for Rural Revitalization in the Course of Agricultural and Forestry Economics and Management in Open Education.
文摘At present, enhancing the digital literacy of village cadres faces practical constraints such as governance capability gaps induced by the second-level digital divide, the absence of a systematic cultivation system, incomplete last-kilometer implementation for translating skills into practice, and inadequate incentive mechanisms. As a novel educational form deeply integrating digital information technology with teaching and learning, distance open education provides multi-directional empowerment for enhancing village cadres digital literacy. This is achieved through open learning methods, the application of modern digital technologies, tailored learning programs, and the establishment of "overpass bridges" for translating learning outcomes into practice. Based on this, it is essential to further streamline the pathways for educating and cultivating village cadres, vigorously promote the digitalization of teaching, practice, and support services, develop systematic and localized digital education resources, and actively explore and establish a complementary credit bank system for their digital literacy cultivation.
文摘在5G与数字生态融合背景下,GSMA Open Gateway通过标准化API与统一接入框架,实现应用在全球运营商网络的可移植与规模化部署,降低开发与适配成本,推动运营商能力开放。然而,跨运营商能力调用仍是关键瓶颈。因此,梳理了CAMARA 4类应用程序编程接口(API)分发模式,对比分析了国内外实践差异。其中,国内运营商针对国内5G网络按需质量保障(QoD)3网互通中聚合平台(Aggregator)面临的痛点,提出了以软件开发工具包(SDK)为核心的解决方案。这一方案通过了统一认证和中国香港商用案例的可行性验证。此外,我国还提出了“SDK+Open Gateway”全球推广与模型上下文协议(MCP)模式演进路径,为全球运营商跨网协同提供中国经验,推动生态从技术框架迈向规模商用,助力数字经济高质量发展。
文摘The Hainan Free Trade Port (FTP) is a key step for China to advance high-standard opening-up and seize a more active role in economic globalization. After early trials, a policy framework has taken shape, and islandwide special customs operations mark a shift from design to full implementation.As of January 18, island-wide special customs operations in Hainan FTP had been in place for a month. The first month ran smoothly, with more efficient flow of goods, people, and capital.This reflects China’s institutional opening-up and, amid slowing global growth, has injected fresh vitality into the regional and global economy.
文摘Objective:Robotic-assisted living donor nephrectomy(RALDN)has been shown to be a safe and feasible option,offering enhanced visualization and improved surgical dexterity,allowing for a potential increase in the living donor pool to perform pediatric and adult kidney transplants,even in cases of grafts with anatomical variants.We report our recent experience in using RALDN for open kidney transplantation(OKT).Methods:Between August 2021 and July 2025,122 kidney transplant recipients underwent OKT using RALDN grafts obtained at the Miami Transplant Institute.Clinical outcomes,during the first12 months post-transplant,including the incidence of delayed graft function(DGF),surgical complications,estimated glomerular filtrationrate(eGFR),and graft loss,were evaluated.Results:Sixteen pediatric and 106 adult recipients were included.The median recipient and donor ages were 42.2 yr and 39.5 yr,respectively.Male recipients comprised 63.1%(77/122);female donors comprised 56.6%(69/122).Among the donors,no conversion to open surgery was needed,and no postoperative complications attributed to the RALDN procedure were observed.Thirty-one kidney grafts required back table reconstruction.The median cold and warm ischemia times were 55.5 min and 27.0 min,respectively.One case(0.8%)of DGF was observed.One recipient(0.8%)developed a postoperative vascular complication;five(4.1%)developed a urologic complication.The median eGFRs at 1 mo,3 mo,6 mo,and 12 mo post-transplant were 71.9,77.1,75.1,and 72.1 mL/min/1.73 m2,respectively.No cases of graft failure during the first12 months post-transplant were observed,and one patient died with a functioning graft.Conclusion:RALDN is a safe and effective technique that provides favorable outcomes among both donors and recipients.This minimally invasive approach should be offered as a safe alternative to living donor patients.
文摘On December 18,2025, Hainan Free Trade Port (Hainan FTP) officially began islandwide special customs operations.Although only two months have passed since this landmark step, the shift is already visible everywhere—from the bustling flow of international passengers at Haikou Meilan International Airport to the steady stream of cargo vessels calling at Yangpu Port, and even in the sustained attention investors are paying to “Hainan-related” stocks.Together, these signals point to one clear conclusion:China’s largest special economic zone has entered a new phase of development.
基金Supported by National Natural Science Foundation of China(No.82260203).
文摘AIM:To study the relationships between amplitude of low-frequency fluctuations(ALFF)changes and clinical ophthalmic parameters in patients with primary open angle glaucoma(POAG)and analyze the diagnostic value of ALFF.METHODS:Twenty-four POAG patients and 24 healthy controls(HCs)underwent resting-state functional magnetic resonance imaging(rs-fMRI).Nonparametric rank-sum tests were used to compare the ALFF values in the slow-4 and slow-5 bands,and Spearman or Pearson correlation analysis was used to assess the correlation between ALFF changes and clinical ophthalmic parameters in POAG patients.Receiver operating characteristic(ROC)curves were used to evaluate the diagnostic performance of the ALFF.RESULTS:There were 16 males in POAG patients(median age 48y)and 12 males in HCs(median age 39y).Compared with HCs,POAG patients presented increased or decreased ALFF values in different brain regions,and similar changes were observed in mild POAG patients.The ALFF values were correlated with retinal nerve fiber layer(RNFL)thickness,inner limiting membrane-retinal pigment epithelium thickness changes and the degree of visual field defects.Analysis of the diagnostic value of the ALFF via ROC curves revealed that the right medial frontal gyrus[area under the curve(AUC)=0.9063]and superior frontal gyrus(AUC=0.9097)had better diagnostic value than did the optic disc area(AUC=0.8019),visual field index(VFI%,AUC=0.8988)and macular parameters.CONCLUSION:POAG patients present altered cortical function that is significantly correlated with the optic nerve and retinal thickness and had good diagnostic value,which may reflect the underlying neuropathological mechanism of POAG.
