Recent years have witnessed significant advances in the development of novel techniques and methodologies for identifying active ingredients in traditional Chinese medicine(TCM),substantially advancing research and de...Recent years have witnessed significant advances in the development of novel techniques and methodologies for identifying active ingredients in traditional Chinese medicine(TCM),substantially advancing research and development efforts.Spectrum-effect correlation analysis,affinity ultrafiltration,high-content screening(HCS)imaging,and cell membrane chromatography(CMC)have emerged as essential tools,effectively linking TCM chemical constituents to their biological effects,thereby enabling efficient active ingredient screening.Additionally,molecular interaction analysis provides deeper insights into TCM-biomolecule interaction mechanisms,enhancing understanding of its therapeutic potential.Computer-aided techniques facilitate TCM active ingredient identification,optimizing the screening process for efficiency and cost-effectiveness.Molecular probe technology,as an emerging methodology,enables precise and rapid screening for novel therapeutic drug discovery.Ongoing technological advancement in this field indicates promising future developments,potentially leading to more effective and targeted TCM-based therapies.展开更多
In the early 18th century,to meet Europe's urgent demand for Jingdezhen's ceramic production techniques,French Jesuit missionary François Xavier d'Entrecolles traveled to Jingdezhen,Jiangxi.While cond...In the early 18th century,to meet Europe's urgent demand for Jingdezhen's ceramic production techniques,French Jesuit missionary François Xavier d'Entrecolles traveled to Jingdezhen,Jiangxi.While conducting missionary work,he thoroughly investigated local porcelain-making techniques.He compiled his findings into two lengthy letters and sent samples of porcelain raw materials to Europe,successfully disseminating Jingdezhen's ceramic artistry to the continent.D'Entrecolles skillfully integrated the protective function of his religious identity,the resource coordination capabilities of political networks,the documentation methods of empirical science,and a localized infiltration strategy,constructing a four-dimensional investigative framework of"missionary integration-observation and interviews-literature review-experimental verification"through Broussonetia papyrifera.These systematic research methods enabled him to comprehensively master Jingdezhen's porcelain technology at the time,establishing him as the pioneer of Western systematic studies on Chinese ceramics and creating a new paradigm of"field research+scientific empiricism"in early cross-cultural technological transmission.展开更多
The component synthesis active vibration suppression method （CSVS） can be applied to suppress the vibration of flexible systems. By this method, several same or similar time-varying components are arranged according...The component synthesis active vibration suppression method （CSVS） can be applied to suppress the vibration of flexible systems. By this method, several same or similar time-varying components are arranged according to certain rules along the time axis. The synthesized command can suppress the arbitrary unwanted vibration harmonic while achieving the desired rigid body motion. The number of the components increases rapidly when the number of harmonic vibration is growing. In this article, the CSVS based on zero-placement technique is used to construct the synthesized command to suppress the multi-harmonics simultaneously in the discrete domain. The nature of zero-placement method is to put enough zeros to cancel system poles at necessary points. The designed synthesized command has equal time intervals between each component and which is much easier to be implemented. Using this method, the number of components increases linearly with the increasing of the number of being suppressed harmonics. For the spacecraft with flexible appendages, CSVS based on zero-placement is used to design the time optimal large angle maneuver control strategy. Simulations have verified the validity and superiority of the proposed approach.展开更多
The estimation of shear strength of rock mass discontinuity is always a focal, but difficult, problem in the field of geotechnical engineering. Considering the disadvantages and limitation of exist- ing estimation met...The estimation of shear strength of rock mass discontinuity is always a focal, but difficult, problem in the field of geotechnical engineering. Considering the disadvantages and limitation of exist- ing estimation methods, a new approach based on the shadow area percentage （SAP） that can be used to quantify surface roughness is proposed in this article. Firstly, by the help of laser scanning technique, the three-dimensional model of the surface of rock discontinuity was established. Secondly, a light source was simulated, and there would be some shadows produced on the model surface. Thirdly, to obtain the value of SAP of each specimen, the shadow detection technique was introduced for use. Fourthly, compared with the result from direct shear testing and based on statistics, an empirical for- mula was found among SAP, normal stress, and shear strength. Data of Yujian （~ River were used as an example, and the following conclusions have been made. （1） In the case of equal normal stress, the peak shear stress is positively proportional to the SAP. （2） The formula for estimating was derived, and the predictions of peak-shear strength made with this equation well agreed with the experimental re- suits obtained in laboratory tests.展开更多
AIM:To evaluate efficacy and safety of clip-and-snare method using pre-looping technique(CSM-PLT)for gastric endoscopic submucosal dissection(ESD).METHODS:In the CSM-PLT method,a clip attached to the lesion side was s...AIM:To evaluate efficacy and safety of clip-and-snare method using pre-looping technique(CSM-PLT)for gastric endoscopic submucosal dissection(ESD).METHODS:In the CSM-PLT method,a clip attached to the lesion side was strangulated with a snare,followed by application of an appropriate tension to the lesion independent of an endoscope.Twenty consecutive lesions were resected by ESD using CSM-PLT(CSM-PLT group)and compared with a control group,including20 lesions that were resected by conventional ESD.The control group was matched based on the size and location of the lesion,presence of pathologic fibrosis,and experience of endoscopists.Total procedure time of ESD,proportion of en bloc resection,and complications were analyzed.RESULTS:The total procedure time for the CSM-PLT group was significantly shorter than that for the control group(38.5 min vs 59.5 min,P=0.023);all lesions were resected en bloc by ESD.There was no significant difference in complications between the two groups.Moreover,there was no complication in the CSM-PLT group.In one large lesion(size:74 mm)that underwentextensive CSM-PLT during ESD,we used an additional CSM-PLT on another edge of the lesion after achieving submucosal resection to the maximum extent possible during initial CSM-PLT.In two lesions,the snare came off the lesion together with the clip after a sudden pull;nevertheless,ESD was successful in all lesions.CONCLUSION:CSM-PLT was an effective and safe method for gastric ESD.展开更多
In this paper, a new class of three term memory gradient method with non-monotone line search technique for unconstrained optimization is presented. Global convergence properties of the new methods are discussed. Comb...In this paper, a new class of three term memory gradient method with non-monotone line search technique for unconstrained optimization is presented. Global convergence properties of the new methods are discussed. Combining the quasi-Newton method with the new method, the former is modified to have global convergence property. Numerical results show that the new algorithm is efficient.展开更多
Comparisons of the common methods for obtaining the periodic responses show that the harmonic balance method with alternating frequency/time （HB-AFT） do- main technique has some advantages in dealing with nonlinear ...Comparisons of the common methods for obtaining the periodic responses show that the harmonic balance method with alternating frequency/time （HB-AFT） do- main technique has some advantages in dealing with nonlinear problems of fractional exponential models. By the HB-AFT method, a rigid rotor supported by ball bearings with nonlinearity of Hertz contact and ball passage vibrations is considered. With the aid of the Floquet theory, the movement characteristics of interval stability are deeply studied. Besides, a simple strategy to determine the monodromy matrix is proposed for the stability analysis.展开更多
In modern transportation,pavement is one of the most important civil infrastructures for the movement of vehicles and pedestrians.Pavement service quality and service life are of great importance for civil engineers a...In modern transportation,pavement is one of the most important civil infrastructures for the movement of vehicles and pedestrians.Pavement service quality and service life are of great importance for civil engineers as they directly affect the regular service for the users.Therefore,monitoring the health status of pavement before irreversible damage occurs is essential for timely maintenance,which in turn ensures public transportation safety.Many pavement damages can be detected and analyzed by monitoring the structure dynamic responses and evaluating road surface conditions.Advanced technologies can be employed for the collection and analysis of such data,including various intrusive sensing techniques,image processing techniques,and machine learning methods.This review summarizes the state-ofthe-art of these three technologies in pavement engineering in recent years and suggests possible developments for future pavement monitoring and analysis based on these approaches.展开更多
The purpose of this study is to develop a standard methodology for measuring the surface free energy (SFE),and its component parts of bamboo fiber materials.The current methods was reviewed to determine the surface te...The purpose of this study is to develop a standard methodology for measuring the surface free energy (SFE),and its component parts of bamboo fiber materials.The current methods was reviewed to determine the surface tension of natural fibers and the disadvantages of techniques used were discussed.Although numerous techniques have been employed to characterize surface tension of natural fibers,it seems that the credibility of results obtained may often be dubious.In this paper,critical surface tension estimates were obtained from computer aided machine vision based measurement.Data were then analyzed by the least squares method to estimate the components of SFE.SFE was estimated by least squares analysis and also by Schultz' method.By using the Fowkes method the polar and disperse fractions of the surface free energy of bamboo fiber materials can be obtained.Strictly speaking,this method is based on a combination of the knowledge of Fowkes theory. SFE is desirable when adhesion is required,and it avoids some of the limitations of existing studies which has been proposed.The calculation steps described in this research are only intended to explain the methods.The results show that the method that only determines SFE as a single parameter may be unable to differentiate adequately between bamboo fiber materials,but it is feasible and very efficient.In order to obtain the maximum performance from the computer aided machine vision based measurement instruments,this measurement should be recommended and kept available for reference.展开更多
Thermoelectric materials have aroused widespread concern due to their unique ability to directly convert heat to electricity without any moving parts or noxious emissions.Taking advantages of two-dimensional structure...Thermoelectric materials have aroused widespread concern due to their unique ability to directly convert heat to electricity without any moving parts or noxious emissions.Taking advantages of two-dimensional structures of thermoelectric films,the potential applications of thermoelectric materials are diversified,particularly in microdevices.Well-controlled nanostructures in thermoelectric films are effective to optimize the electrical and thermal transport,which can significantly improve the performance of thermoelectric materials.In this paper,various physical and chemical approaches to fabricate thermoelectric films,including inorganic,organic,and inorganic–organic composites,are summarized,where more attentions are paid on the inorganic thermoelectric films for their excellent thermoelectric responses.Additionally,strategies for enhancing the performance of thermoelectric films are also discussed.展开更多
Most cities around the world, including Abuja Municipal are being faced with an undesirable increased in air temperature. This is indicated by an increase in non-porous, non-evaporating, highly thermal conductive surf...Most cities around the world, including Abuja Municipal are being faced with an undesirable increased in air temperature. This is indicated by an increase in non-porous, non-evaporating, highly thermal conductive surfaces such as concrete and asphalt, which has replaced the vegetation biomass resulting to the formation of urban heat island. There is an increasing need for studies on the changing trend of UHI intensity in cities. This research employed geospatial techniques to determine the urban heat island intensity in Abuja Municipal. Temperature characteristics over twenty selected rural and urban locations in Abuja, FCT were derived from the satellite image of 1986, 2001 and 2016 using the “Extract Multi Values to Point” tool in ArcGIS 10.4. These transects pass over various landscapes with different environmental settings, with the aim of understanding the factors shaping the city’s thermal landscape. The intervals of +15 years were deliberately chosen to ensure uniformity between the datasets. The results of this analysis indicate that UHII has been increasing, from 1986-2016, giving credence to the results of the spatial and temporal analysis of the land surface temperature, indicating the development phases had hit full stride. The different periods under study (1986, 2001 and 2016) were also tested using the student “t” test to determine the significant difference in the land surface temperature values to acknowledge the presence of a substantial urban heat island within the study area. The result reveals the calculated “t” values of 2.50, 3.34, 5.57 of 1986, 2001 and 2016 respectively, are higher than the critical value of “t” at 0.05 being 1.73, thus, revealing the temperature differences between the urban and rural stations to be highly significant, indicating the presence of a strong urban heat island. Also, a slide difference in the temperature was observed with the Rubuchi and Karmajiji rural areas having higher temperature readings than their counterparts in the urban areas, Asokoro and Garki, with readings of <span style="white-space:nowrap;">−</span>0.4<span style="white-space:nowrap;">°</span>C and <span style="white-space:nowrap;">−</span>1.3<span style="white-space:nowrap;">°</span>C. Since effectiveness of a surface in reducing daytime urban air temperatures depends strongly on the amount of heating avoided, the study recommends preserving and replicating greenery, light coloured facades as measures to reduce the effects of urban heat island.展开更多
The genetic algorithm has been widely used in many fields as an easy robust global search and optimization method. In this paper, a new generic algorithm based on niche technique and local search method is presented u...The genetic algorithm has been widely used in many fields as an easy robust global search and optimization method. In this paper, a new generic algorithm based on niche technique and local search method is presented under the consideration of inadequacies of the simple genetic algorithm. In order to prove the adaptability and validity of the improved genetic algorithm, optimization problems of multimodal functions with equal peaks, unequal peaks and complicated peak distribution are discussed. The simulation results show that compared to other niching methods, this improved genetic algorithm has obvious potential on many respects, such as convergence speed, solution accuracy, ability of global optimization, etc.展开更多
Based on years of input from the four geodetic techniques （SLR, GPS, VLBI and DORIS）, the strategies of the combination were studied in SHAO to generate a new global terrestrial reference frame as the material reali...Based on years of input from the four geodetic techniques （SLR, GPS, VLBI and DORIS）, the strategies of the combination were studied in SHAO to generate a new global terrestrial reference frame as the material realization of the ITRS defined in IERS Conventions. The main input includes the time series of weekly solutions （or fortnightly for SLR 1983-1993） of observational data for satellite techniques and session-wise normal equations for VLBI. The set of estimated unknowns includes 3- dimensional Cartesian coordinates at the reference epoch 2005.0 of the stations distributed globally and their rates as well as the time series of consistent Earth Orientation Parameters （EOPs） at the same epochs as the input. Besides the final solution, namely SOL-2, generated by using all the inputs before 2015.0 obtained from short-term observation processing, another reference solution, namely SOL- 1, was also computed by using the input before 2009.0 based on the same combination of procedures for the purpose of comparison with ITRF2008 and DTRF2008 and for evaluating the effect of the latest six more years of data on the combined results. The estimated accuracy of the x-component and y-component of the SOL- 1 TRF-origin was better than 0.1 mm at epoch 2005.0 and better than 0.3 mm yr- 1 in time evolution, either compared with ITRF2008 or DTRF2008. However, the z-component of the translation parameters from SOL-1 to ITRF2008 and DTRF2008 were 3.4 mm and -1.0 ram, respectively. It seems that the z-component of the SOL-1 TRF-origin was much closer to the one in DTRF2008 than the one in ITRF2008. The translation parameters from SOL-2 to ITRF2014 were 2.2, -1.8 and 0.9 mm in the x-, y- and z-components respectively with rates smaller than 0.4 mmyr-1. Similarly, the scale factor transformed from SOL-1 to DTRF2008 was much smaller than that to ITRF2008. The scale parameter from SOL-2 to ITRF2014 was -0.31 ppb with a rate lower than 0.01 ppb yr-1. The external precision （WRMS） compared with IERS EOP 08 C04 of the combined EOP series was smaller than 0.06 mas for the polar motions, smaller than 0.01 ms for the UT1-UTC and smaller than 0.02 ms for the LODs. The precision of the EOPs in SOL-2 was slightly higher than that of SOL-1.展开更多
Short-term traffic flow prediction is one of the essential issues in intelligent transportation systems(ITS). A new two-stage traffic flow prediction method named AKNN-AVL method is presented, which combines an advanc...Short-term traffic flow prediction is one of the essential issues in intelligent transportation systems(ITS). A new two-stage traffic flow prediction method named AKNN-AVL method is presented, which combines an advanced k-nearest neighbor(AKNN)method and balanced binary tree(AVL) data structure to improve the prediction accuracy. The AKNN method uses pattern recognition two times in the searching process, which considers the previous sequences of traffic flow to forecast the future traffic state. Clustering method and balanced binary tree technique are introduced to build case database to reduce the searching time. To illustrate the effects of these developments, the accuracies performance of AKNN-AVL method, k-nearest neighbor(KNN) method and the auto-regressive and moving average(ARMA) method are compared. These methods are calibrated and evaluated by the real-time data from a freeway traffic detector near North 3rd Ring Road in Beijing under both normal and incident traffic conditions.The comparisons show that the AKNN-AVL method with the optimal neighbor and pattern size outperforms both KNN method and ARMA method under both normal and incident traffic conditions. In addition, the combinations of clustering method and balanced binary tree technique to the prediction method can increase the searching speed and respond rapidly to case database fluctuations.展开更多
As an important geophysical tool,high density electrical technique infers the underground geological structures by processing and inverting the apparent resistivity data.Currently,the false anomalies have been frequen...As an important geophysical tool,high density electrical technique infers the underground geological structures by processing and inverting the apparent resistivity data.Currently,the false anomalies have been frequently occurred in the graph of apparent resistivity pseudo-section or inverted geoelectrical section obtained from high-density electrical technique,and are difficult to remove.In this study,the authors explain the mechanism of the false anomalies and put forward the horizontal differential field method to identify the false anomalies.Based on the analysis of modeling results,this method is applied in the surveying data in Xinlei Quarry of Jiuquan,and the results confirm the effectiveness of the horizontal differential field method.展开更多
The situation of electricity in Pakistan has been alarming from the last ten years. The deficiency in electricity has not only obstructed the business activities but also affected the domestic consumers, educational i...The situation of electricity in Pakistan has been alarming from the last ten years. The deficiency in electricity has not only obstructed the business activities but also affected the domestic consumers, educational institutes and hospitals. Usually electrical power companies are liable for electricity shortfall and power interruption. However, electricity end consumers are also equally responsible behind strange shortfall and unusual power interruption. Frequently, the consumers use the heavy electrical equipment in their homes including heaters, geysers, irons and water motors which causes the more electricity consumption, load shedding and huge amount of bills. For escaping the huge amount of electricity bill, the consumers commit the illegal and unethical connections. The illegal usage of electrical power failed the power companies to plan schedule load shedding accordingly and the other side the damaged electricity wires or Pole Mount Transformer increased faults due to overburdening, which directly affected on extend power interruption. In addition that, responsible teams of electrical power companies cannot reach instantly to repair faults and prevent the theft. Electricity thieving is social crime committed by the consumers or meter readers which causes the electricity strange shortfall within country. This paper presents the practical demonstration about the common energy theft methods and techniques done by electricity consumers within their home and residential building. In Pakistan EPC (electrical power companies) deploy the traditional electromechanical meters for electricity consumption measurements, however, these meters do not have any real time communication. Therefore there are many easy ways to manipulate the meter reading as well as internal structural of metering system.展开更多
Patch-clamp technique serve as a powerful tool for precisely measuring and characterizing ion channel currents,offering critical molecular-level insights essential for drug screening and optimization.By enabling a dee...Patch-clamp technique serve as a powerful tool for precisely measuring and characterizing ion channel currents,offering critical molecular-level insights essential for drug screening and optimization.By enabling a deeper understanding of ion channel behavior,these techniques significantly accelerate the process of drug discovery and development.In recent years,automated patch-clamp technique has undergone substantial advancements,surpassing traditional manual methods with its high throughput,improved data consistency,and automation.However,fully harnessing these advantages requires meticulous optimization of experimental conditions tailored to specific targets.Without such refinement,the high cost of consumables and operational expenses could severely hinder the widespread adoption of this technique.This study focused on the TRPV1 channel,detailing the establishment of an automated patch-clamp detection system for TRPV1 currents,optimization of experimental parameters,and a comparative evaluation of the results against manual patch-clamp techniques.展开更多
Pure titanium fabricated by powder metallurgy generally encounters problems including low relative density and low strength,which limits its application performance.This work proposed a multi-step pressing(MSP)techniq...Pure titanium fabricated by powder metallurgy generally encounters problems including low relative density and low strength,which limits its application performance.This work proposed a multi-step pressing(MSP)technique for developing highstrength pure titanium.The MSP processes of spherical Ti powders of 15–53μm,53–105μm,and 75–180μm were systematically investigated through multi-particle fnite element method(MPFEM)compared with conventional one-step pressing(OSP)technique.The relative density,phase constitution,microstructure,and compressive mechanical properties of the sintered bulk pure titanium were characterized.Simulation results demonstrate that the MSP technique signifcantly increases the relative density of green compacts by 3.2%,3.3%,and 5.2%,respectively,compared with OSP technique.Experimental results indicate the relative density of the sintered specimens prepared by MSP spherical powders increases by 5.4%,4.5%,and 4.5%,respectively,compared to OSP,and the yield strength improves by 16%,13%,and 18%.For the sintered specimens prepared by MSP irregular powder of 15–53μm,the relative density increases by 6.0%and the yield strength increases by 15%.The enhancement of relative density and yield strength is mainly because the MSP technique mitigates stress concentration between powder particles.Compared to spherical powder,irregular powder exhibits stronger mechanical interlocking owing to the greater propensity for displacement and deformation,which facilitates mutual wedging and interlocking,resulting in superior strength performance.展开更多
This paper proposes an inexact Newton method via the Lanczos decomposed technique for solving the box-constrained nonlinear systems. An iterative direction is obtained by solving an affine scaling quadratic model with...This paper proposes an inexact Newton method via the Lanczos decomposed technique for solving the box-constrained nonlinear systems. An iterative direction is obtained by solving an affine scaling quadratic model with the Lanczos decomposed technique. By using the interior backtracking line search technique, an acceptable trial step length is found along this direction. The global convergence and the fast local convergence rate of the proposed algorithm are established under some reasonable conditions. Furthermore, the results of the numerical experiments show the effectiveness of the pro- posed algorithm.展开更多
The crack tip strain gauge method in the compliance technique was used to determine the opening load of notched crack of axle steel,and the nonlinear finite element ADINA program, to which the cyclic stress-strain cur...The crack tip strain gauge method in the compliance technique was used to determine the opening load of notched crack of axle steel,and the nonlinear finite element ADINA program, to which the cyclic stress-strain curve of axle steel was applied,was used to analyze the stress-strain field ahead of the crack tip and the opening load of notched crack.The results of both the compliance technique and the numerical method were in good agreement.In this pa- per,the concept of the sensitive point is proposed and the key to the determination of the crack opening load in the experiment is to place a strain gauge at sensitive point.It is certified by both experimental and numerical methods that the sensitive point has the best linear relation- ship character and the value of strain is much greater.展开更多
基金supported by the National Natural Science Foundation of China (Nos. 22175078, 52373287, 82404846, and 22467002)the Natural Science Foundation of Jiangsu Province of China (No. BK20241597)the Fundamental Research Funds for the Central Universities (No. 2632024TD05)
文摘Recent years have witnessed significant advances in the development of novel techniques and methodologies for identifying active ingredients in traditional Chinese medicine(TCM),substantially advancing research and development efforts.Spectrum-effect correlation analysis,affinity ultrafiltration,high-content screening(HCS)imaging,and cell membrane chromatography(CMC)have emerged as essential tools,effectively linking TCM chemical constituents to their biological effects,thereby enabling efficient active ingredient screening.Additionally,molecular interaction analysis provides deeper insights into TCM-biomolecule interaction mechanisms,enhancing understanding of its therapeutic potential.Computer-aided techniques facilitate TCM active ingredient identification,optimizing the screening process for efficiency and cost-effectiveness.Molecular probe technology,as an emerging methodology,enables precise and rapid screening for novel therapeutic drug discovery.Ongoing technological advancement in this field indicates promising future developments,potentially leading to more effective and targeted TCM-based therapies.
文摘In the early 18th century,to meet Europe's urgent demand for Jingdezhen's ceramic production techniques,French Jesuit missionary François Xavier d'Entrecolles traveled to Jingdezhen,Jiangxi.While conducting missionary work,he thoroughly investigated local porcelain-making techniques.He compiled his findings into two lengthy letters and sent samples of porcelain raw materials to Europe,successfully disseminating Jingdezhen's ceramic artistry to the continent.D'Entrecolles skillfully integrated the protective function of his religious identity,the resource coordination capabilities of political networks,the documentation methods of empirical science,and a localized infiltration strategy,constructing a four-dimensional investigative framework of"missionary integration-observation and interviews-literature review-experimental verification"through Broussonetia papyrifera.These systematic research methods enabled him to comprehensively master Jingdezhen's porcelain technology at the time,establishing him as the pioneer of Western systematic studies on Chinese ceramics and creating a new paradigm of"field research+scientific empiricism"in early cross-cultural technological transmission.
文摘The component synthesis active vibration suppression method （CSVS） can be applied to suppress the vibration of flexible systems. By this method, several same or similar time-varying components are arranged according to certain rules along the time axis. The synthesized command can suppress the arbitrary unwanted vibration harmonic while achieving the desired rigid body motion. The number of the components increases rapidly when the number of harmonic vibration is growing. In this article, the CSVS based on zero-placement technique is used to construct the synthesized command to suppress the multi-harmonics simultaneously in the discrete domain. The nature of zero-placement method is to put enough zeros to cancel system poles at necessary points. The designed synthesized command has equal time intervals between each component and which is much easier to be implemented. Using this method, the number of components increases linearly with the increasing of the number of being suppressed harmonics. For the spacecraft with flexible appendages, CSVS based on zero-placement is used to design the time optimal large angle maneuver control strategy. Simulations have verified the validity and superiority of the proposed approach.
基金supported by the China Geological Survey (No.1212011014030)the Major State Basic Research Development Program of China (973 Program) (No.2011CB710600)
文摘The estimation of shear strength of rock mass discontinuity is always a focal, but difficult, problem in the field of geotechnical engineering. Considering the disadvantages and limitation of exist- ing estimation methods, a new approach based on the shadow area percentage （SAP） that can be used to quantify surface roughness is proposed in this article. Firstly, by the help of laser scanning technique, the three-dimensional model of the surface of rock discontinuity was established. Secondly, a light source was simulated, and there would be some shadows produced on the model surface. Thirdly, to obtain the value of SAP of each specimen, the shadow detection technique was introduced for use. Fourthly, compared with the result from direct shear testing and based on statistics, an empirical for- mula was found among SAP, normal stress, and shear strength. Data of Yujian （~ River were used as an example, and the following conclusions have been made. （1） In the case of equal normal stress, the peak shear stress is positively proportional to the SAP. （2） The formula for estimating was derived, and the predictions of peak-shear strength made with this equation well agreed with the experimental re- suits obtained in laboratory tests.
文摘AIM:To evaluate efficacy and safety of clip-and-snare method using pre-looping technique(CSM-PLT)for gastric endoscopic submucosal dissection(ESD).METHODS:In the CSM-PLT method,a clip attached to the lesion side was strangulated with a snare,followed by application of an appropriate tension to the lesion independent of an endoscope.Twenty consecutive lesions were resected by ESD using CSM-PLT(CSM-PLT group)and compared with a control group,including20 lesions that were resected by conventional ESD.The control group was matched based on the size and location of the lesion,presence of pathologic fibrosis,and experience of endoscopists.Total procedure time of ESD,proportion of en bloc resection,and complications were analyzed.RESULTS:The total procedure time for the CSM-PLT group was significantly shorter than that for the control group(38.5 min vs 59.5 min,P=0.023);all lesions were resected en bloc by ESD.There was no significant difference in complications between the two groups.Moreover,there was no complication in the CSM-PLT group.In one large lesion(size:74 mm)that underwentextensive CSM-PLT during ESD,we used an additional CSM-PLT on another edge of the lesion after achieving submucosal resection to the maximum extent possible during initial CSM-PLT.In two lesions,the snare came off the lesion together with the clip after a sudden pull;nevertheless,ESD was successful in all lesions.CONCLUSION:CSM-PLT was an effective and safe method for gastric ESD.
文摘In this paper, a new class of three term memory gradient method with non-monotone line search technique for unconstrained optimization is presented. Global convergence properties of the new methods are discussed. Combining the quasi-Newton method with the new method, the former is modified to have global convergence property. Numerical results show that the new algorithm is efficient.
基金supported by the National Natural Science Foundation of China(No.10632040)
文摘Comparisons of the common methods for obtaining the periodic responses show that the harmonic balance method with alternating frequency/time （HB-AFT） do- main technique has some advantages in dealing with nonlinear problems of fractional exponential models. By the HB-AFT method, a rigid rotor supported by ball bearings with nonlinearity of Hertz contact and ball passage vibrations is considered. With the aid of the Floquet theory, the movement characteristics of interval stability are deeply studied. Besides, a simple strategy to determine the monodromy matrix is proposed for the stability analysis.
基金supported by the National Key R&D Program of China(2017YFF0205600)the International Research Cooperation Seed Fund of Beijing University of Technology(2018A08)+1 种基金Science and Technology Project of Beijing Municipal Commission of Transport(2018-kjc-01-213)the Construction of Service Capability of Scientific and Technological Innovation-Municipal Level of Fundamental Research Funds(Scientific Research Categories)of Beijing City(PXM2019_014204_500032).
文摘In modern transportation,pavement is one of the most important civil infrastructures for the movement of vehicles and pedestrians.Pavement service quality and service life are of great importance for civil engineers as they directly affect the regular service for the users.Therefore,monitoring the health status of pavement before irreversible damage occurs is essential for timely maintenance,which in turn ensures public transportation safety.Many pavement damages can be detected and analyzed by monitoring the structure dynamic responses and evaluating road surface conditions.Advanced technologies can be employed for the collection and analysis of such data,including various intrusive sensing techniques,image processing techniques,and machine learning methods.This review summarizes the state-ofthe-art of these three technologies in pavement engineering in recent years and suggests possible developments for future pavement monitoring and analysis based on these approaches.
基金the National Natural Science Foundation of China(No.31101085)the Scientific Research and Development Foundation for Start-up Projects of Zhejiang Agriculture and Forestry University (No.2034020044)
文摘The purpose of this study is to develop a standard methodology for measuring the surface free energy (SFE),and its component parts of bamboo fiber materials.The current methods was reviewed to determine the surface tension of natural fibers and the disadvantages of techniques used were discussed.Although numerous techniques have been employed to characterize surface tension of natural fibers,it seems that the credibility of results obtained may often be dubious.In this paper,critical surface tension estimates were obtained from computer aided machine vision based measurement.Data were then analyzed by the least squares method to estimate the components of SFE.SFE was estimated by least squares analysis and also by Schultz' method.By using the Fowkes method the polar and disperse fractions of the surface free energy of bamboo fiber materials can be obtained.Strictly speaking,this method is based on a combination of the knowledge of Fowkes theory. SFE is desirable when adhesion is required,and it avoids some of the limitations of existing studies which has been proposed.The calculation steps described in this research are only intended to explain the methods.The results show that the method that only determines SFE as a single parameter may be unable to differentiate adequately between bamboo fiber materials,but it is feasible and very efficient.In order to obtain the maximum performance from the computer aided machine vision based measurement instruments,this measurement should be recommended and kept available for reference.
基金Project supported by the Joint Funds of the National Natural Science Foundation of China(Grant No.U1601213)the National Natural Science Foundation of China(Grant Nos.51601005 and 61704006)+1 种基金the Beijing Natural Science Foundation(Grant No.2182032)the Fundamental Research Funds for the Central Universities
文摘Thermoelectric materials have aroused widespread concern due to their unique ability to directly convert heat to electricity without any moving parts or noxious emissions.Taking advantages of two-dimensional structures of thermoelectric films,the potential applications of thermoelectric materials are diversified,particularly in microdevices.Well-controlled nanostructures in thermoelectric films are effective to optimize the electrical and thermal transport,which can significantly improve the performance of thermoelectric materials.In this paper,various physical and chemical approaches to fabricate thermoelectric films,including inorganic,organic,and inorganic–organic composites,are summarized,where more attentions are paid on the inorganic thermoelectric films for their excellent thermoelectric responses.Additionally,strategies for enhancing the performance of thermoelectric films are also discussed.
文摘Most cities around the world, including Abuja Municipal are being faced with an undesirable increased in air temperature. This is indicated by an increase in non-porous, non-evaporating, highly thermal conductive surfaces such as concrete and asphalt, which has replaced the vegetation biomass resulting to the formation of urban heat island. There is an increasing need for studies on the changing trend of UHI intensity in cities. This research employed geospatial techniques to determine the urban heat island intensity in Abuja Municipal. Temperature characteristics over twenty selected rural and urban locations in Abuja, FCT were derived from the satellite image of 1986, 2001 and 2016 using the “Extract Multi Values to Point” tool in ArcGIS 10.4. These transects pass over various landscapes with different environmental settings, with the aim of understanding the factors shaping the city’s thermal landscape. The intervals of +15 years were deliberately chosen to ensure uniformity between the datasets. The results of this analysis indicate that UHII has been increasing, from 1986-2016, giving credence to the results of the spatial and temporal analysis of the land surface temperature, indicating the development phases had hit full stride. The different periods under study (1986, 2001 and 2016) were also tested using the student “t” test to determine the significant difference in the land surface temperature values to acknowledge the presence of a substantial urban heat island within the study area. The result reveals the calculated “t” values of 2.50, 3.34, 5.57 of 1986, 2001 and 2016 respectively, are higher than the critical value of “t” at 0.05 being 1.73, thus, revealing the temperature differences between the urban and rural stations to be highly significant, indicating the presence of a strong urban heat island. Also, a slide difference in the temperature was observed with the Rubuchi and Karmajiji rural areas having higher temperature readings than their counterparts in the urban areas, Asokoro and Garki, with readings of <span style="white-space:nowrap;">−</span>0.4<span style="white-space:nowrap;">°</span>C and <span style="white-space:nowrap;">−</span>1.3<span style="white-space:nowrap;">°</span>C. Since effectiveness of a surface in reducing daytime urban air temperatures depends strongly on the amount of heating avoided, the study recommends preserving and replicating greenery, light coloured facades as measures to reduce the effects of urban heat island.
文摘The genetic algorithm has been widely used in many fields as an easy robust global search and optimization method. In this paper, a new generic algorithm based on niche technique and local search method is presented under the consideration of inadequacies of the simple genetic algorithm. In order to prove the adaptability and validity of the improved genetic algorithm, optimization problems of multimodal functions with equal peaks, unequal peaks and complicated peak distribution are discussed. The simulation results show that compared to other niching methods, this improved genetic algorithm has obvious potential on many respects, such as convergence speed, solution accuracy, ability of global optimization, etc.
基金supported by the Ministry of Science and Technology of China(2015FY310200)the National Key Research and Development Program of China(2016YFB0501405)+1 种基金the National Natural Science Foundation of China(11173048 and 11403076)the State Key Laboratory of Aerospace Dynamics and the Crustal Movement Observation Network of China(CMONOC)
文摘Based on years of input from the four geodetic techniques （SLR, GPS, VLBI and DORIS）, the strategies of the combination were studied in SHAO to generate a new global terrestrial reference frame as the material realization of the ITRS defined in IERS Conventions. The main input includes the time series of weekly solutions （or fortnightly for SLR 1983-1993） of observational data for satellite techniques and session-wise normal equations for VLBI. The set of estimated unknowns includes 3- dimensional Cartesian coordinates at the reference epoch 2005.0 of the stations distributed globally and their rates as well as the time series of consistent Earth Orientation Parameters （EOPs） at the same epochs as the input. Besides the final solution, namely SOL-2, generated by using all the inputs before 2015.0 obtained from short-term observation processing, another reference solution, namely SOL- 1, was also computed by using the input before 2009.0 based on the same combination of procedures for the purpose of comparison with ITRF2008 and DTRF2008 and for evaluating the effect of the latest six more years of data on the combined results. The estimated accuracy of the x-component and y-component of the SOL- 1 TRF-origin was better than 0.1 mm at epoch 2005.0 and better than 0.3 mm yr- 1 in time evolution, either compared with ITRF2008 or DTRF2008. However, the z-component of the translation parameters from SOL-1 to ITRF2008 and DTRF2008 were 3.4 mm and -1.0 ram, respectively. It seems that the z-component of the SOL-1 TRF-origin was much closer to the one in DTRF2008 than the one in ITRF2008. The translation parameters from SOL-2 to ITRF2014 were 2.2, -1.8 and 0.9 mm in the x-, y- and z-components respectively with rates smaller than 0.4 mmyr-1. Similarly, the scale factor transformed from SOL-1 to DTRF2008 was much smaller than that to ITRF2008. The scale parameter from SOL-2 to ITRF2014 was -0.31 ppb with a rate lower than 0.01 ppb yr-1. The external precision （WRMS） compared with IERS EOP 08 C04 of the combined EOP series was smaller than 0.06 mas for the polar motions, smaller than 0.01 ms for the UT1-UTC and smaller than 0.02 ms for the LODs. The precision of the EOPs in SOL-2 was slightly higher than that of SOL-1.
基金Project(2012CB725403)supported by the National Basic Research Program of ChinaProjects(71210001,51338008)supported by the National Natural Science Foundation of ChinaProject supported by World Capital Cities Smooth Traffic Collaborative Innovation Center and Singapore National Research Foundation Under Its Campus for Research Excellence and Technology Enterprise(CREATE)Programme
文摘Short-term traffic flow prediction is one of the essential issues in intelligent transportation systems(ITS). A new two-stage traffic flow prediction method named AKNN-AVL method is presented, which combines an advanced k-nearest neighbor(AKNN)method and balanced binary tree(AVL) data structure to improve the prediction accuracy. The AKNN method uses pattern recognition two times in the searching process, which considers the previous sequences of traffic flow to forecast the future traffic state. Clustering method and balanced binary tree technique are introduced to build case database to reduce the searching time. To illustrate the effects of these developments, the accuracies performance of AKNN-AVL method, k-nearest neighbor(KNN) method and the auto-regressive and moving average(ARMA) method are compared. These methods are calibrated and evaluated by the real-time data from a freeway traffic detector near North 3rd Ring Road in Beijing under both normal and incident traffic conditions.The comparisons show that the AKNN-AVL method with the optimal neighbor and pattern size outperforms both KNN method and ARMA method under both normal and incident traffic conditions. In addition, the combinations of clustering method and balanced binary tree technique to the prediction method can increase the searching speed and respond rapidly to case database fluctuations.
文摘As an important geophysical tool,high density electrical technique infers the underground geological structures by processing and inverting the apparent resistivity data.Currently,the false anomalies have been frequently occurred in the graph of apparent resistivity pseudo-section or inverted geoelectrical section obtained from high-density electrical technique,and are difficult to remove.In this study,the authors explain the mechanism of the false anomalies and put forward the horizontal differential field method to identify the false anomalies.Based on the analysis of modeling results,this method is applied in the surveying data in Xinlei Quarry of Jiuquan,and the results confirm the effectiveness of the horizontal differential field method.
文摘The situation of electricity in Pakistan has been alarming from the last ten years. The deficiency in electricity has not only obstructed the business activities but also affected the domestic consumers, educational institutes and hospitals. Usually electrical power companies are liable for electricity shortfall and power interruption. However, electricity end consumers are also equally responsible behind strange shortfall and unusual power interruption. Frequently, the consumers use the heavy electrical equipment in their homes including heaters, geysers, irons and water motors which causes the more electricity consumption, load shedding and huge amount of bills. For escaping the huge amount of electricity bill, the consumers commit the illegal and unethical connections. The illegal usage of electrical power failed the power companies to plan schedule load shedding accordingly and the other side the damaged electricity wires or Pole Mount Transformer increased faults due to overburdening, which directly affected on extend power interruption. In addition that, responsible teams of electrical power companies cannot reach instantly to repair faults and prevent the theft. Electricity thieving is social crime committed by the consumers or meter readers which causes the electricity strange shortfall within country. This paper presents the practical demonstration about the common energy theft methods and techniques done by electricity consumers within their home and residential building. In Pakistan EPC (electrical power companies) deploy the traditional electromechanical meters for electricity consumption measurements, however, these meters do not have any real time communication. Therefore there are many easy ways to manipulate the meter reading as well as internal structural of metering system.
基金The National Natural Science Foundation of China(Grant No.32000674).
文摘Patch-clamp technique serve as a powerful tool for precisely measuring and characterizing ion channel currents,offering critical molecular-level insights essential for drug screening and optimization.By enabling a deeper understanding of ion channel behavior,these techniques significantly accelerate the process of drug discovery and development.In recent years,automated patch-clamp technique has undergone substantial advancements,surpassing traditional manual methods with its high throughput,improved data consistency,and automation.However,fully harnessing these advantages requires meticulous optimization of experimental conditions tailored to specific targets.Without such refinement,the high cost of consumables and operational expenses could severely hinder the widespread adoption of this technique.This study focused on the TRPV1 channel,detailing the establishment of an automated patch-clamp detection system for TRPV1 currents,optimization of experimental parameters,and a comparative evaluation of the results against manual patch-clamp techniques.
基金supports from the National Natural Science Foundation of China(No.52404382)the Key Research and Development Project of Shaanxi Province(No.2023-YBGY-090).
文摘Pure titanium fabricated by powder metallurgy generally encounters problems including low relative density and low strength,which limits its application performance.This work proposed a multi-step pressing(MSP)technique for developing highstrength pure titanium.The MSP processes of spherical Ti powders of 15–53μm,53–105μm,and 75–180μm were systematically investigated through multi-particle fnite element method(MPFEM)compared with conventional one-step pressing(OSP)technique.The relative density,phase constitution,microstructure,and compressive mechanical properties of the sintered bulk pure titanium were characterized.Simulation results demonstrate that the MSP technique signifcantly increases the relative density of green compacts by 3.2%,3.3%,and 5.2%,respectively,compared with OSP technique.Experimental results indicate the relative density of the sintered specimens prepared by MSP spherical powders increases by 5.4%,4.5%,and 4.5%,respectively,compared to OSP,and the yield strength improves by 16%,13%,and 18%.For the sintered specimens prepared by MSP irregular powder of 15–53μm,the relative density increases by 6.0%and the yield strength increases by 15%.The enhancement of relative density and yield strength is mainly because the MSP technique mitigates stress concentration between powder particles.Compared to spherical powder,irregular powder exhibits stronger mechanical interlocking owing to the greater propensity for displacement and deformation,which facilitates mutual wedging and interlocking,resulting in superior strength performance.
基金Project supported by the National Natural Science Foundation of China (No. 10871130)the Ph. D.Programs Foundation of Ministry of Education of China (No. 20093127110005)the Shanghai Leading Academic Discipline Project (No. T0401)
文摘This paper proposes an inexact Newton method via the Lanczos decomposed technique for solving the box-constrained nonlinear systems. An iterative direction is obtained by solving an affine scaling quadratic model with the Lanczos decomposed technique. By using the interior backtracking line search technique, an acceptable trial step length is found along this direction. The global convergence and the fast local convergence rate of the proposed algorithm are established under some reasonable conditions. Furthermore, the results of the numerical experiments show the effectiveness of the pro- posed algorithm.
文摘The crack tip strain gauge method in the compliance technique was used to determine the opening load of notched crack of axle steel,and the nonlinear finite element ADINA program, to which the cyclic stress-strain curve of axle steel was applied,was used to analyze the stress-strain field ahead of the crack tip and the opening load of notched crack.The results of both the compliance technique and the numerical method were in good agreement.In this pa- per,the concept of the sensitive point is proposed and the key to the determination of the crack opening load in the experiment is to place a strain gauge at sensitive point.It is certified by both experimental and numerical methods that the sensitive point has the best linear relation- ship character and the value of strain is much greater.
