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Numerical Simulation of Shrinkage Cavity Formation in Spheroidal Graphite Iron Castings Based on Micro Modeling 被引量:5
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作者 Wenzhen Li Baicheng Liu Shantong Jin (Metallurgy Engineering School, University of Science and Technology Beijing, Beijing 100083, China)(Department of Mechanical Engineering, Tsinghua University, Beijing 100084, China) 《International Journal of Minerals,Metallurgy and Materials》 SCIE EI CAS CSCD 1998年第1期9-12,共4页
A micro-modeling method (MM) for the quantitative prediction of the shrinkage cavity formation in SGiron castings is proposed. The mathematical models describing the volume changes during the solidification ofspheroid... A micro-modeling method (MM) for the quantitative prediction of the shrinkage cavity formation in SGiron castings is proposed. The mathematical models describing the volume changes during the solidification ofspheroidal graphite cast iron are established based on the models of solidification kinetics. The shrinkage cavityformation of T-shaped SG iron castings is calculated with MM method. The calculated results are compared with theexperimental results. It is shown that the predicted size, shape and distribution of shrinkage cavity by MM methodare in good agreement with the measured results. 展开更多
关键词 SOLIDIFICATION SHRINKAGE numerical simulation micro modeling spheroidal graphite cast iron
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Micro Model of Carbon Fiber/Cyanate Ester Composites and Analysis of Machining Damage Mechanism 被引量:6
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作者 Haitao Liu Jie Lin +1 位作者 Yazhou Sun Jinyang Zhang 《Chinese Journal of Mechanical Engineering》 SCIE EI CAS CSCD 2019年第3期198-208,共11页
Machining damage occurs on the surface of carbon fiber reinforced polymer (CFRP) composites during processing. In the current simulation model of CFRP, the initial defects on the carbon fiber and the periodic random d... Machining damage occurs on the surface of carbon fiber reinforced polymer (CFRP) composites during processing. In the current simulation model of CFRP, the initial defects on the carbon fiber and the periodic random distribution of the reinforcement phase in the matrix are not considered in detail, which makes the characteristics of the cutting model significantly different from the actual processing conditions. In this paper, a novel three-phase model of carbon fiber/cyanate ester composites is proposed to simulate the machining damage of the composites. The periodic random distribution of the carbon fiber reinforced phase in the matrix was realized using a double perturbation algorithm. To achieve the stochastic distribution of the strength of a single carbon fiber, a novel method that combines the Weibull intensity distribution theory with the Monte Carlo method is presented. The mechanical properties of the cyanate matrix were characterized by fitting the stress-strain curves, and the cohesive zone model was employed to simulate the interface. Based on the model, the machining damage mechanism of the composites was revealed using finite element simulations and by conducting a theoretical analysis. Furthermore, the milling surfaces of the composites were observed using a scanning electron microscope, to verify the accuracy of the simulation results. In this study, the simulations and theoretical analysis of the carbon fiber/cyanate ester composite processing were carried out based on a novel three-phase model, which revealed the material failure and machining damage mechanism more accurately. 展开更多
关键词 Carbon fiber reinforced polymer COMPOSITES micro simulation model MACHINING damage mechanism MILLING and observation experiment Theoretical ANALYSIS
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基于micro-CT实验的颗粒体系接触力计算及演化分析 被引量:1
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作者 王潇 宋世琦 +3 位作者 平子健 盛思源 商宪义 陈凡秀 《物理学报》 北大核心 2025年第1期207-217,共11页
三维颗粒体系颗粒间接触力计算是散体力学研究的重难点.以双弹性橡胶球为研究对象,开展显微CT(micro-CT)原位平压实验,基于Hertz接触理论和Tatara大变形接触理论,验证了弹性球接触模型,获得了基于实验的弹性球接触力理论公式.以三维颗... 三维颗粒体系颗粒间接触力计算是散体力学研究的重难点.以双弹性橡胶球为研究对象,开展显微CT(micro-CT)原位平压实验,基于Hertz接触理论和Tatara大变形接触理论,验证了弹性球接触模型,获得了基于实验的弹性球接触力理论公式.以三维颗粒体系为研究对象,开展了micro-CT原位探针加载实验,获取颗粒二维图像序列,经过系列数字变换得到数字体图像,获得了不同加载状态下三维颗粒体系接触力网络,分析了颗粒体系接触力分布及演化规律,探究了强接触数量及分布演化与颗粒体系稳定性的联系.研究结果表明:基于实验的弹性球接触力公式能合理有效表征两颗粒间的接触力;探针加载下颗粒间接触力呈现以探针压头接触点为起点,向下方和四周逐级传递接触力的网状分布;强接触数量占接触总数量的45%-50%,分布贯穿于整个颗粒体系内部,支撑起颗粒体系网络结构,较大值集中于压头下方呈现树杈状分布;加载过程中,z=14 mm处建立了平衡点,平衡点处,强接触数量达到顶峰,强接触力网络结构布满整个三维颗粒体系,建立起承受外载荷的主要骨架,随着加载继续,强接触力的整体数值更高,在颗粒体系内部分布也更加均匀. 展开更多
关键词 显微CT 原位加载 颗粒接触模型 接触力
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Micro-LED晶圆缺陷检测的宽光谱大视场显微物镜设计
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作者 洪惠敏 贺文俊 《光子学报》 北大核心 2025年第3期207-220,共14页
为了实现对Micro-LED晶圆缺陷的准确和高效检测,设计了一款工作波长覆盖可见光和近红外的宽光谱、大视场、平场、复消色差显微物镜。采用正-正-负三光组结构,计算调整了各光组光焦度并分配其元件特征,实现了大视场和长工作距设计。基于B... 为了实现对Micro-LED晶圆缺陷的准确和高效检测,设计了一款工作波长覆盖可见光和近红外的宽光谱、大视场、平场、复消色差显微物镜。采用正-正-负三光组结构,计算调整了各光组光焦度并分配其元件特征,实现了大视场和长工作距设计。基于Buchdahl色散模型进行了玻璃材料的色散矢量分析并指导了初始光学系统材料替换,实现了平场复消色差设计。设计结果表明:该显微物镜的工作波长范围为420 nm~1064 nm、放大倍率为10倍、视场为3.3 mm、数值孔径为0.34、可见光波段分辨率为0.88μm、近红外波段分辨率为1.35μm、工作距为8 mm、齐焦距为95 mm。其成像质量优良,调制传递函数曲线接近衍射极限,全谱段复消色差,全视场平坦,易于加工生产,可用于检测大范围的表面以及次表面的微米级Micro-LED晶圆缺陷。 展开更多
关键词 光学设计 显微物镜 Buchdahl模型 平场复消色差 micro-LED
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基于Micro-CT分析大豆种子结构表型及构建种子重量预测模型 被引量:1
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作者 刘长斌 李远鲲 +3 位作者 郭民坤 樊江川 郭新宇 卢宪菊 《大豆科学》 北大核心 2025年第1期11-21,共11页
大豆是重要的粮油兼用作物,是植物蛋白质的重要来源,为明确大豆种子结构特征并构建种子重量预测模型,以42个不同大豆品种为材料,利用Micro-CT技术扫描测试样本,通过CT图像的处理解析,获取大豆种子的长度、宽度、厚度、体积、表面积、种... 大豆是重要的粮油兼用作物,是植物蛋白质的重要来源,为明确大豆种子结构特征并构建种子重量预测模型,以42个不同大豆品种为材料,利用Micro-CT技术扫描测试样本,通过CT图像的处理解析,获取大豆种子的长度、宽度、厚度、体积、表面积、种胚体积、表面积及空腔体积特征,人工称重测定单粒重量指标。系统分析种子形态特征及其与重量的相关关系,并对不同品种进行聚类分析,通过对多项形态表型和重量指标进行主成分分析,确定主要贡献指标,基于机器学习算法构建重量预测模型。结果表明:种子形态特征与种子重量显著相关,但种子形状特征对重量无显著影响;42个大豆品种可以分为4类,其中第一类品种蒙豆375和蒙豆60的种子大小和重量指标均显著高于其他3类品种。利用随机森林模型和偏最小二乘回归方法构建的重量预测模型效果优于单一指标的简单线性回归效果。其中,随机森林回归模型训练集和测试集的R^(2)分别为0.80和0.66,RMSE分别为0.017和0.021 g,偏最小二乘回归模型训练集和测试集的R^(2)分别为0.75和0.72,RMSE分别为0.019和0.020 g。研究结果为大豆种子外部形态和内部结构的研究提供了新的技术和方法,为大豆品种分类、产量和品质性状的评价提供理论和技术参考。 展开更多
关键词 micro-CT 大豆 结构表型 重量预测 模型构建 机器学习
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Micro-CT在拔牙后位点保存动物模型中的应用
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作者 杨志康 姜雨汐 《口腔医学研究》 北大核心 2025年第9期743-749,共7页
拔牙后牙槽嵴高度和宽度的维持和再生直接影响种植修复效果,显微计算机断层扫描(micro computed tomography,Micro-CT/μ-CT)技术因其分辨率高、可三维成像和定量分析等优势,成为评估位点保存效果的重要影像学测量工具。但由于动物模型... 拔牙后牙槽嵴高度和宽度的维持和再生直接影响种植修复效果,显微计算机断层扫描(micro computed tomography,Micro-CT/μ-CT)技术因其分辨率高、可三维成像和定量分析等优势,成为评估位点保存效果的重要影像学测量工具。但由于动物模型选择、系统程序应用、图像采集方法、图像评估和定量分析方式差异大这一研究现状,使读者难以系统、定量、科学地比较分析各类手术方案或骨再生材料在不同研究中的修复效果与参数,导致难以依据文献结果得出最佳决策。因此,本文在Micro-CT成像系统的组成和工作原理、动物模型选择的基础上,综述了Micro-CT在拔牙后位点保存动物模型研究中的样本的放置与固定、图像采集设备参数选择、感兴趣区圈画方式、常规与特异性定量指标意义和选择考量方式,并总结技术未来发展方向和挑战,以期推动Micro-CT技术在牙槽骨保存研究中的标准形成,提高数据分析的准确性、可重复性和可比性。 展开更多
关键词 micro-CT 位点保存 动物模型 定量分析 牙槽骨缺损
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Designing of optimized microstrip fractal antenna using hybrid metaheuristic framework for IoT applications
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作者 S KARUNAKAR Reddy ANITHA Guttavelli 《Journal of Systems Engineering and Electronics》 2025年第3期659-670,共12页
Nowadays,wireless communication devices turn out to be transportable owing to the execution of the current technologies.The antenna is the most important component deployed for communication purposes.The antenna plays... Nowadays,wireless communication devices turn out to be transportable owing to the execution of the current technologies.The antenna is the most important component deployed for communication purposes.The antenna plays an imperative role in receiving and transmitting the signals for any sensor network.Among varied antennas,micro strip fractal antenna(MFA)significantly contributes to increasing antenna gain.This study employs a hybrid optimization method known as the elephant clan updated grey wolf algorithm to introduce an optimized MFA design.This method optimizes antenna characteristics,including directivity and gain.Here,the factors,including length,width,ground plane length,height,and feed offset-X and feed offset-Y,are taken into account to achieve the best performance of gain and directivity.Ultimately,the superiority of the suggested technique over state-of-the-art strategies is calculated for various metrics such as cost and gain.The adopted model converges to a minimal value of 0.2872.Further,the spider monkey optimization(SMO)model accomplishes the worst performance over all other existing models like elephant herding optimization(EHO),grey wolf optimization(GWO),lion algorithm(LA),support vector regressor(SVR),bacterial foraging-particle swarm optimization(BF-PSO)and shark smell optimization(SSO).Effective MFA design is obtained using the suggested strategy regarding various parameters. 展开更多
关键词 micro strip fractal antenna(MFA)model gain DIRECTIVITY support vector regressor(SVR)approach elephant clan updated grey wolf algorithm(ECU-GWA)
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CALCULATION OF THE DAMPING OF THE Zn-27Al ALLOY BASED ON THE MICRO INTERFACE SLIDING MODEL 被引量:2
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作者 Y.Z. Zhao Q. Gao Y.C. Liu 《Acta Metallurgica Sinica(English Letters)》 SCIE EI CAS CSCD 2006年第3期228-234,共7页
The microstructures of the Zn-27Al alloy after modification, solid-solution treatment, and natural aging were studied. It was clarified why the damping properties of Zn-27Al alloys, after treatment, had advanced most ... The microstructures of the Zn-27Al alloy after modification, solid-solution treatment, and natural aging were studied. It was clarified why the damping properties of Zn-27Al alloys, after treatment, had advanced most on the basis of analyzing the microstructures. Approximate expressions have been educed, which can be used to quantificationally work out the damping of the Zn-27Al alloy on the basis of the micro interface sliding model. By comparing the testing damping properties of the foundry Zn-27Al alloys and the Zn-27Al alloys after modification, solid solution, and natural aging, it was shown that the expressions were rational. 展开更多
关键词 MODIFICATION solid solution and aging damping micromechanism micro interface sliding model
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Crystal Plasticity Finite Element Process Modeling for Hydro-forming Micro-tubular Components 被引量:4
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作者 ZHUANG Weimin WANG Shiwen +1 位作者 BALINT Daniel LIN Jianguo 《Chinese Journal of Mechanical Engineering》 SCIE EI CAS CSCD 2011年第1期78-83,共6页
Micro-tubes manufactured by hydro-forming techniques have now been widely used in medical and microelectronics applica- tions. One of the difficulties in forming such parts is the control of localized necking in the i... Micro-tubes manufactured by hydro-forming techniques have now been widely used in medical and microelectronics applica- tions. One of the difficulties in forming such parts is the control of localized necking in the initial stages of the deformation/forming process. A lack of microstructural information causes conventional macro-mechanics finite element(FE) tools to break down when used to investigate the localized microstructure evolution and necking encountered in micro-forming. An effort has been made to create an integrated crystal plasticity finite element(CPFE) system that enables micro-forming process simulations to be carried out easily, with the important features in forming micro-parts captured by the model. Based on Voronoi tessellation and probability theory, a virtual GRAIN(VGRAIN) system is created for generating grains and grain boundaries for micro-materials. Numerical procedures are devel- oped to link the physical parameters of a material to the control variables in a Gamma distribution. A script interface is developed so that the virtual microstructure can be input to the commercial FE code, ABAQUS, for mesh generation. A simplified plane strain CPFE modeling technique is developed and used to capture localized thinning and failure features for hydro-forming of micro-tubes. Grains within the tube workpiece, their distributions and orientations are generated automatically by using the VGRAIN system. A set of crystal viscoplasticity constitutive equations are implemented in ABAQUS/Explicit by using the user-defined material subroutine, VUMAT. Lo- calized thinning is analyzed for different microstructures and deformation conditions of the material using the CPFE modeling technique. The research results show that locations of thinning in forming micro-tubes can be random, which are related to microstructure and grain orientations of the material. The proposed CPFE technique can be used to predict the locations of thinning in forming micro-tubes. 展开更多
关键词 micro-mechanics modeling micro-FORMING hydro-forming
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Compressive failure analysis of unidirectional carbon/epoxy composite based on micro-mechanical models 被引量:6
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作者 Wei SUN Zhidong GUAN +2 位作者 Zengshan LI Mi ZHANG Yongjie HUANG 《Chinese Journal of Aeronautics》 SCIE EI CAS CSCD 2017年第6期1907-1918,共12页
A 2D micro-mechanical model was proposed to study the compressive failure of Uni Directional(UD) carbon/epoxy composite. Considering the initial imperfection and strength distribution of the fiber, the plasticity an... A 2D micro-mechanical model was proposed to study the compressive failure of Uni Directional(UD) carbon/epoxy composite. Considering the initial imperfection and strength distribution of the fiber, the plasticity and ductile damage of the matrix, the failure of T300/914 UD composite under longitudinal compression and in-plane combined loads was simulated by this model. Simulation results show that the longitudinal compressive failure of the UD composite is caused by the plastic yielding of the matrix in kink band, and the fiber initial imperfection is the main reason for it. Under in-plane combined loads, the stress state of the matrix in kink band is changed, which affects the longitudinal compressive failure modes and strength of UD composite.The failure envelope of r_1–s_(12) and r_1–r_2 are obtained by the micro-mechanical model. Meanwhile,the compressive failure mechanism of the UD composite is analyzed. Numerical results agree well with the experimental data, which verifies the validity of the micro-mechanical model. 展开更多
关键词 micro-mechanical model Unidirectional composite Initial imperfection Matrix plasticity Ductile damage Kink band
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A Micro-layer Model for the Lubrication Effect Near Collisions of Immersed Particles 被引量:1
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作者 李彦鹏 《过程工程学报》 CAS CSCD 北大核心 2006年第z2期379-384,共6页
A micro-layer model is proposed to account for the lubrication effect of liquid layer near collisions of immersed particles at moderate particle Reynolds number.This new model is to allow determination of the pressure... A micro-layer model is proposed to account for the lubrication effect of liquid layer near collisions of immersed particles at moderate particle Reynolds number.This new model is to allow determination of the pressure profile within the micro-layer including the fluid inertia and viscosity.Then a correction based on the micro-layer model is applied to unsteady 3-D direct simulation of a particle approaching another one.The simulation is based on a modified immersed boundary method with direct force scheme.The quantitative agreement between numerical and experimental results validates the model presented in the study.The simulation results show that the fluid is squeezed prior to contact.When a particle approaches a flat wall or another particle,the lubrication force,obtained by integrating the pressure profile over the particle surface,is increased and prevents the particle from approaching.The model predicts that the velocity of approaching particle starts to decrease when separation distance of particles is less than 0.1dp,where dp is the particle diameter. 展开更多
关键词 LUBRICATION EFFECT micro-layer model immersed BOUNDARY method
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A composite material model for investigation of micro-fracture mechanism of brittle rock subjected to uniaxial compression 被引量:4
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作者 CHEN Feng,SUN Zong qi,XU Ji cheng,ZHANG Jing yi (Key Laboratory of Nonferrous Metal Materials Science & Engineering, Central South University, Changsha 410083, China) 《Journal of Central South University of Technology》 2001年第4期258-262,共5页
A two phase model of rock was proposed in order to investigate the mechanism of brittle fracture due to uniaxial compression, in which rock was considered to be a composite material consisting of hard grains and collo... A two phase model of rock was proposed in order to investigate the mechanism of brittle fracture due to uniaxial compression, in which rock was considered to be a composite material consisting of hard grains and colloids. The stress state in colloid region near grains was calculated using Finite Element Method (FEM). The influence of the tensile stresses on the crack initiation and failure process of brittle rock subjected to uniaxial compression was investigated by numerical experiments. The FE results show that tensile stresses are induced easily in the neighboring area of hard grains with the maximum value near grain boundaries. The distribution of tensile stresses depends on the relative position of hard grains. The cracks initiated just near the boundary area of hard grains, which was governed by tensile stress. These results clearly reveal the micro fracture mechanism of brittle rock loaded by uniaxial compression. It can be concluded that the failure mode of brittle rock under uniaxial compression is still tensile fracture from the point view of microstructure. However, since the wide colloid region is still under compressive stress state, further propagation of boundary cracks through this region obviously needs more external load, thus causing the uniaxial compressive strength of rock much higher than its tensile strength obtained via Brazilian (splitting) 展开更多
关键词 TWO-PHASE model micro-FRACTURE ROCK UNIAXIAL compression
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A Fractional Micro-Macro Model for Crowds of Pedestrians Based on Fractional Mean Field Games 被引量:1
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作者 Kecai Cao Yang Quan Chen Daniel Stuart 《IEEE/CAA Journal of Automatica Sinica》 SCIE EI 2016年第3期261-270,共10页
Modeling a crowd of pedestrians has been considered in this paper from different aspects. Based on fractional microscopic model that may be much more close to reality, a fractional macroscopic model has been proposed ... Modeling a crowd of pedestrians has been considered in this paper from different aspects. Based on fractional microscopic model that may be much more close to reality, a fractional macroscopic model has been proposed using conservation law of mass. Then in order to characterize the competitive and cooperative interactions among pedestrians, fractional mean field games are utilized in the modeling problem when the number of pedestrians goes to infinity and fractional dynamic model composed of fractional backward and fractional forward equations are constructed in macro scale. Fractional micromacro model for crowds of pedestrians are obtained in the end. Simulation results are also included to illustrate the proposed fractional microscopic model and fractional macroscopic model, respectively. © 2014 Chinese Association of Automation. 展开更多
关键词 Control systems Electrical engineering
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Improved social force model based on exit selection for microscopic pedestrian simulation in subway station 被引量:4
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作者 郑勋 李海鹰 +2 位作者 孟令云 许心越 陈旭 《Journal of Central South University》 SCIE EI CAS CSCD 2015年第11期4490-4497,共8页
An improved social force model based on exit selection is proposed to simulate pedestrians' microscopic behaviors in subway station. The modification lies in considering three factors of spatial distance, occupant... An improved social force model based on exit selection is proposed to simulate pedestrians' microscopic behaviors in subway station. The modification lies in considering three factors of spatial distance, occupant density and exit width. In addition, the problem of pedestrians selecting exit frequently is solved as follows: not changing to other exits in the affected area of one exit, using the probability of remaining preceding exit and invoking function of exit selection after several simulation steps. Pedestrians in subway station have some special characteristics, such as explicit destinations, different familiarities with subway station. Finally, Beijing Zoo Subway Station is taken as an example and the feasibility of the model results is verified through the comparison of the actual data and simulation data. The simulation results show that the improved model can depict the microscopic behaviors of pedestrians in subway station. 展开更多
关键词 EXIT SELECTION SOCIAL FORCE model EXIT WIDTH micro
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Numerical modeling of time-dependent deformation and induced stresses in concrete pipes constructed in Queenston shale using micro-tunneling technique 被引量:1
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作者 Hayder Mohammed Salim Al-Maamori M.Hesham El Naggar Silvana Micic 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2018年第2期290-309,共20页
Effects of time-dependent deformation(TDD) on a tunnel constructed using the micro-tunneling technique in Queenston shale(QS) are investigated employing the finite element method. The TDD and strength parameters o... Effects of time-dependent deformation(TDD) on a tunnel constructed using the micro-tunneling technique in Queenston shale(QS) are investigated employing the finite element method. The TDD and strength parameters of the QS were measured from tests conducted on QS specimens soaked in water and lubricant fluids(LFs) used in micro-tunneling such as bentonite and polymer solutions. The numerical model was verified using the results of TDD tests performed on QS samples, field measurements of some documented projects, and the closed-form solutions to circular tunnels in swelling rock. The verified model was then employed to conduct a parametric study considering important micro-tunneling design parameters, such as depth and diameter of the tunnel, in situ stress ratio(K;), and the time lapse prior to replacing LFs with permanent cement grout around the tunnel. It was revealed that the time lapse plays a vital role in controlling deformations and associated stresses developed in the tunnel lining.The critical case of a pipe or tunnel in which the maximum tensile stress develops at its springline occurs when it is constructed at shallow depths in the QS layer. The results of the parametric study were used to suggest recommendations for the construction of tunnels in QS employing micro-tunneling. 展开更多
关键词 Numerical model micro-tunneling Queenston shale(QS) Lubricant fluids(LFs)
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Macro and micro mechanics behavior of granite after heat treatment by cluster model in particle flow code 被引量:8
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作者 Wen-Ling Tian Sheng-Qi Yang Yan-Hua Huang 《Acta Mechanica Sinica》 SCIE EI CAS CSCD 2018年第1期175-186,共12页
In this paper, a cluster model in particle flow code was used to simulate granite specimens after heat treatment under uniaxial compression. The results demonstrated that micro-cracks are randomly distributed in the s... In this paper, a cluster model in particle flow code was used to simulate granite specimens after heat treatment under uniaxial compression. The results demonstrated that micro-cracks are randomly distributed in the specimen when the temperature is below 300?C, and have partial coalescence when the temperature is up to 450?C, then form macro-cracks when the temperature is above 600?C. There is more inter-granular cracking than intra-granular cracking, and their ratio increases with increasing temperature.The micro-cracks are almost constant when the temperature decreases from 900?C to room temperature, except for quartz α–β phase transition temperature(573?C). The fracture evolution process is obviously affected by these cracks, especially at 600–900?C. Elevated temperature leads to easily developed displacement between the grains, and the capacity to store strain energy becomes weaker, corresponding to the plasticity of granite after heat treatment. 展开更多
关键词 Cluster model GRANITE Thermal damage micro-CRACK Energy
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基于Micro-CT的BALB/c小鼠肺腺瘤动物模型研究 被引量:2
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作者 简芹 向思睿 +5 位作者 王楚楚 陈芜 付西 由凤鸣 郑川 林俊芝 《中国实验动物学报》 CAS CSCD 北大核心 2024年第4期485-492,共8页
目的 建立基于Micro-CT动态表征的BALB/c小鼠肺腺瘤动物模型研究方法。方法 取80只SPF级雌性BALB/c小鼠,随机分为4组:模型低剂量组(1 mg/g乌拉坦腹腔注射1次)、模型中剂量组(1 mg/g乌拉坦腹腔注射,每周1次,连续2周)、模型高剂量组(1 mg/... 目的 建立基于Micro-CT动态表征的BALB/c小鼠肺腺瘤动物模型研究方法。方法 取80只SPF级雌性BALB/c小鼠,随机分为4组:模型低剂量组(1 mg/g乌拉坦腹腔注射1次)、模型中剂量组(1 mg/g乌拉坦腹腔注射,每周1次,连续2周)、模型高剂量组(1 mg/g乌拉坦腹腔注射,每周1次,连续4周)和空白组(等体积生理盐水腹腔注射)。采用Micro-CT定期监测小鼠肺结节生长情况,Analyze 12.0分析系统绘制小鼠肺部3D图像,苏木素-伊红(HE)染色观察肺组织病理学变化。结果 与空白组相比,各模型组小鼠第11周时均观测到类圆形高密度影的肺结节。结节形成率随造模周数增加而升高,至第21周时,模型高、中、低剂量组结节形成率分别为93.8%、93.8%、87.5%;结节数分别以2~4个、1个、1~2个为主;低剂量组肺结节最大直径平均值高于中、高剂量组(P<0.05);肺结节体积三组之间差异无统计学意义。HE染色结果显示模型高、中、低剂量组病理类型均为肺腺瘤。结论 模型各剂量组均成功诱导肺腺瘤,Micro-CT可对小鼠肺结节生长情况进行表征,其中模型中剂量组结节形成率高,肺腺瘤数量适中,模型稳定,更适合小鼠肺腺瘤动物模型的研究。 展开更多
关键词 乌拉坦 BALB/C小鼠 肺腺瘤 micro-CT 动物模型
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Micro sliding friction model considering periodic variation stress distribution of contact surface and experimental verification
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作者 卢晟昊 韩靖宇 阎绍泽 《Chinese Physics B》 SCIE EI CAS CSCD 2023年第4期452-466,共15页
Micro sliding phenomenon widely exists in the operation process of mechanical systems,and the micro sliding friction mechanism is always a research hotspot.In this work,based on the total reflection method,a measuring... Micro sliding phenomenon widely exists in the operation process of mechanical systems,and the micro sliding friction mechanism is always a research hotspot.In this work,based on the total reflection method,a measuring device for interface contact behavior under two-dimensional(2D)vibration is built.The stress distribution is characterized by the light intensity distribution of the contact image,and the interface contact behavior in the 2D vibration process is studied.It is found that the vibration angle of the normal direction of the contact surface and its fluctuation affect the interface friction coefficient,the tangential stiffness,and the fluctuation amplitude of the stress distribution.Then they will affect the change of friction state and energy dissipation in the process of micro sliding.Further,an improved micro sliding friction model is proposed based on the experimental analysis,with the nonlinear change of contact parameters caused by the normal contact stress distribution fluctuation taken into account.This model considers the interface tangential stiffness fluctuation,friction coefficient hysteresis,and stress distribution fluctuation,whose simulation results are consistent well with the experimental results.It is found that considering the nonlinear effect of a certain contact parameter alone may bring a greater error to the prediction of friction behavior.Only by integrating multiple contact parameters can the accuracy of friction prediction is improved. 展开更多
关键词 periodic variation stress distribution micro sliding friction model tangential stiffness experimental analysis STICK-SLIP
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PROTOTYPE SURFACE MICRO- PRECISION IN FUSED DEPOSITION MODELING PROCESS 被引量:2
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作者 WANG Tianming XI Juntong JIN Ye 《Chinese Journal of Mechanical Engineering》 SCIE EI CAS CSCD 2007年第1期100-106,共7页
To aim at prototype parts fabricated with fused deposition modeling (FDM) process, the problems how to improve and enhance their surface micro-precision are studied. The producing mechanism of surface roughness is e... To aim at prototype parts fabricated with fused deposition modeling (FDM) process, the problems how to improve and enhance their surface micro-precision are studied. The producing mechanism of surface roughness is explained with three aspects concretely including the principle error of rapid prototyping (RP) process, the inherent characteristics of FDM process, and some mi- cro-scratches on the surface of the extruded fiber. Based on the micro-characters of section shape of the FDM prototype, a physical model reflecting the outer shape characters is abstracted. With the physical simplified and deduced, the evaluating equations of surface roughness are acquired. According to the FDM sample parts with special design for experimental measurement, the real surface roughness values of different inclined planes are obtained. And the measuring values of surface roughness are compared with the calculation values. Furthermore, the causes of surface roughness deviation between measuring values and calculation values are respectively analyzed and studied. With the references of analytic conclusions, the measuring values of the experimental part surface are revised, and the revised values nearly accord with the calculation values. Based on the influencing principles of FDM process parameters and special post processing of FDM prototype parts, some concrete measures are proposed to reduce the surface roughness of FDM parts, and the applying effects are better. 展开更多
关键词 Rapid prototyping Fused deposition modeling micro-precision Surface roughness Post processing sequence
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Model construction of micro-pores in shale: A case study of Silurian Longmaxi Formation shale in Dianqianbei area, SW China 被引量:2
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作者 CHEN Keluo ZHANG Tingshan +2 位作者 CHEN Xiaohui HE Yingjie LIANG Xing 《Petroleum Exploration and Development》 2018年第3期412-421,共10页
Based on scanning electron microscopy and nitrogen adsorption experiment at low temperature, the pore types and structures of the Longmaxi Formation shale in the Dianqianbei area, SW China were analyzed, and a molecul... Based on scanning electron microscopy and nitrogen adsorption experiment at low temperature, the pore types and structures of the Longmaxi Formation shale in the Dianqianbei area, SW China were analyzed, and a molecular model was built. According to mathematical statistics, the validation of the model was solved by converting it into a mathematical formula. It is found by SEM that the pores in clay mineral layers and organic pores occupy most of the pores in shale; the nitrogen adsorption experiment at low temperature reveals that groove pores formed by flaky particles and micro-pores are the main types of pores, and the results of the two are in good agreement. A molecular model was established by illite and graphene molecular structures. Moreover, based on the fractal theory and the Frenkel-Halsey-Hill formula, a modified Frenkel-Halsey-Hill formula was proposed. The reliability of the molecular model was verified to some extent by obtaining parameters such as the fractal dimension, replacement rate and fractal coefficients of correction, and mathematical calculation. This study provides the theoretical basis for quantitative study of shale reservoirs. 展开更多
关键词 Dianqianbei area SHALE SILURIAN Longmaxi Formation micro-pore PORE model model verification
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