In this paper,we study a class of Linear Fractional Programming on a nonempty bounded set,called the Problem(LFP),and design a branch and bound algorithm to find the global optimal solution of the problem(LFP).First,w...In this paper,we study a class of Linear Fractional Programming on a nonempty bounded set,called the Problem(LFP),and design a branch and bound algorithm to find the global optimal solution of the problem(LFP).First,we convert the problem(LFP)to the equivalent problem(EP2).Secondly,by applying the linear relaxation technique to the problem(EP2),the linear relaxation programming problem(LRP2Y)was obtained.Then,the overall framework of the algorithm is given,and the convergence and complexity of the algorithm are analyzed.Finally,experimental results are listed to illustrate the effectiveness of the algorithm.展开更多
The operational demands of a wide range significantly exacerbate combustion instability issues within ramjet combustor.To suppress combustion oscillations,an open-loop control system utilizing Linear Genetic Programmi...The operational demands of a wide range significantly exacerbate combustion instability issues within ramjet combustor.To suppress combustion oscillations,an open-loop control system utilizing Linear Genetic Programming(LGP)has been developed for a full-scale annular ramjet combustor.The LGP is used to generate control laws that include multi-frequency forcing.These laws are then transformed into square waves to actuate the solenoid valve,which modulates the kerosene supply for open-loop control.The results show that the duty cycle has little effect on instability amplitude,whereas an increase in frequency leads to a remarked reduction in combustion amplitude.After five generations evolvements,the pressure amplitude is reduced by 40.6% under the optimal control law generated by LGP.Furthermore,the machine learning process is depicted using a proximity map of control law similarity,with the search pathway visualized by the steepest descent.All individuals go forward to the upper left corner of the map with the evolution process,terminating at the optimal individual of the fifth generation.展开更多
During the use of robotics in applications such as antiterrorism or combat,a motion-constrained pursuer vehicle,such as a Dubins unmanned surface vehicle(USV),must get close enough(within a prescribed zero or positive...During the use of robotics in applications such as antiterrorism or combat,a motion-constrained pursuer vehicle,such as a Dubins unmanned surface vehicle(USV),must get close enough(within a prescribed zero or positive distance)to a moving target as quickly as possible,resulting in the extended minimum-time intercept problem(EMTIP).Existing research has primarily focused on the zero-distance intercept problem,MTIP,establishing the necessary or sufficient conditions for MTIP optimality,and utilizing analytic algorithms,such as root-finding algorithms,to calculate the optimal solutions.However,these approaches depend heavily on the properties of the analytic algorithm,making them inapplicable when problem settings change,such as in the case of a positive effective range or complicated target motions outside uniform rectilinear motion.In this study,an approach employing a high-accuracy and quality-guaranteed mixed-integer piecewise-linear program(QG-PWL)is proposed for the EMTIP.This program can accommodate different effective interception ranges and complicated target motions(variable velocity or complicated trajectories).The high accuracy and quality guarantees of QG-PWL originate from elegant strategies such as piecewise linearization and other developed operation strategies.The approximate error in the intercept path length is proved to be bounded to h^(2)/(4√2),where h is the piecewise length.展开更多
Linear programming(LP)decoding is a classic decoding method for linear block codes,and has attracted recent researches because its potential in joint channel processing.However,for polar codes,LP decoders has long bee...Linear programming(LP)decoding is a classic decoding method for linear block codes,and has attracted recent researches because its potential in joint channel processing.However,for polar codes,LP decoders has long been outperformed by CRCaided successive cancellation list(CA-SCL)decoders.To increase the competitiveness of 5G NR LP polar decoding,it is possible to gain performance improvements by exploiting the cyclic redundancy check(CRC)setup.In this paper,we propose a combined scheme of reduced sparsified factor graph-sparsified CRC(RSFG-SCRC)and augmented generator matrix-CRC(AGM-CRC),for polytope generation in adaptive linear programming(ALP)decoder for 5G polar codes.Augmented generator matrix(AGM)polytope and improved maximum cycle strategy-auxiliary node pairs 4(MCS-ANP-4)algorithm are proposed,to make efficient use of CRC constraints and minimize the constraint size for the decoder.Numerical simulations show that adaptive linear programming decoders with our proposed RSFG-SCRC and AGM-CRC polytopes can achieve significantly better block error rate(BLER)performance than a benchmark CA-SCL-8 decoder especially in harsh low-to-medium SNR regions.展开更多
现有电力负荷预测方法面临诸多挑战,尤其是在考虑气象因素对负荷波动的影响时,传统方法往往忽视气象特征与负荷之间复杂的非线性关系,导致预测精度不足。对此文中提出一种基于气象相似日修正(meteorological similar day correction,MS...现有电力负荷预测方法面临诸多挑战,尤其是在考虑气象因素对负荷波动的影响时,传统方法往往忽视气象特征与负荷之间复杂的非线性关系,导致预测精度不足。对此文中提出一种基于气象相似日修正(meteorological similar day correction,MSDC)和改进鹦鹉优化(improved parrot optimizer,IPO)线性分解(decomposition-based linear,DLinear)的日前电力负荷预测模型。首先运用Logistic映射、自适应变异策略、螺旋波动搜索IPO对DLinear超参数进行优化,然后由DLinear提取数据的周期性和趋势性特征,最后通过比对气象特征欧氏距离修正负荷预测值,形成基于IPO-DLinear-MSDC的日前电力负荷预测模型。采用2024年6月至10月湖南株洲地区总电力负荷数据集进行仿真分析,IPO-DLinear-MSDC模型的输出平均绝对百分比误差(mean absolute percentage error,MAPE)、决定系数R2分别为4.67%、0.833,相较于IPO-DLinear与PO-DLinear模型,MAPE分别下降了0.83个百分点、1.43个百分点,R2分别提升了0.074、0.125。展开更多
Two new linear furocoumarins were isolated from Notopterygium incisum using silica gel,gel Sephadex LH-20 column chromatography,and preparative high-performance liquid chromatography.The structures of the new compound...Two new linear furocoumarins were isolated from Notopterygium incisum using silica gel,gel Sephadex LH-20 column chromatography,and preparative high-performance liquid chromatography.The structures of the new compounds were elucidated through analysis of spectroscopic evidence,including data obtained from high-resolution electrospray ionization mass spectrometry(HRESIMS)and nuclear magnetic resonance(NMR).The absolute configurations of Notoprenylate L(1)and Nototerprinol K(2)were further confirmed using electronic circular dichroism(ECD)calculations.Compound 1 demonstrated the ability to inhibit the expression of nitric oxide(NO),a pro-inflammatory factor,in lipopolysaccharide-induced RAW264.7 macrophages at a concentration of 7.5μmol/L,indicating its potential for anti-inflammatory activity.展开更多
Online programming platforms are popular in programming education.However,there has been no research investigating students’real opinions and expectations of the error feedback mechanisms,leaving educators without a ...Online programming platforms are popular in programming education.However,there has been no research investigating students’real opinions and expectations of the error feedback mechanisms,leaving educators without a solid data foundation when attempting to improve the error feedback mechanisms.This paper makes a survey of 834 students across various programming courses and investigates student perceptions of error feedback mechanisms on online programming platforms.It explores the effectiveness of existing feedback,student satisfaction,and preferences for potential improvements,focusing on automatic error localization and program repair mechanisms.Results reveal a significant portion of students are dissatisfied with current feedback due to its limited informativeness.Students also express a clear demand for stronger feedback mechanisms,such as error localization and repair hints.Nevertheless,they prefer feedback that subtly guides them toward solutions,rather than providing direct and explicit answers,valuing the opportunity to enhance their debugging skills.The findings suggest a need for balanced,educational-focused feedback mechanisms that aid learning while promoting independent problem-solving.展开更多
The growing prevalence of exercise-induced tibial stress fractures demands wearable sensors capable of monitoring dynamic musculoskeletal loads with medical-grade precision.While flexible pressure-sensing insoles show...The growing prevalence of exercise-induced tibial stress fractures demands wearable sensors capable of monitoring dynamic musculoskeletal loads with medical-grade precision.While flexible pressure-sensing insoles show clinical potential,their development has been hindered by the intrinsic trade-off between high sensitivity and full-range linearity(R^(2)>0.99 up to 1 MPa)in conventional designs.Inspired by the tactile sensing mechanism of human skin,where dermal stratification enables wide-range pressure adaptation and ion-channelregulated signaling maintains linear electrical responses,we developed a dual-mechanism flexible iontronic pressure sensor(FIPS).This innovative design synergistically combines two bioinspired components:interdigitated fabric microstructures enabling pressure-proportional contact area expansion(αP1/3)and iontronic film facilitating self-adaptive ion concentration modulation(αP^(2/3)),which together generate a linear capacitance-pressure response(CαP).The FIPS achieves breakthrough performance:242 kPa^(-1)sensitivity with 0.997linearity across 0-1 MPa,yielding a record linear sensing factor(LSF=242,000).The design is validated across various substrates and ionic materials,demonstrating its versatility.Finally,the FIPS-driven design enables a smart insole demonstrating 1.8%error in tibial load assessment during gait analysis,outperforming nonlinear counterparts(6.5%error)in early fracture-risk prediction.The biomimetic design framework establishes a universal approach for developing high-performance linear sensors,establishing generalized principles for medical-grade wearable devices.展开更多
Rydberg-atom-based superheterodyne receivers integrate self-calibration,high sensitivity,a wide operational frequency range,and phase/frequency resolved detection capabilities,demonstrating broad application prospects...Rydberg-atom-based superheterodyne receivers integrate self-calibration,high sensitivity,a wide operational frequency range,and phase/frequency resolved detection capabilities,demonstrating broad application prospects as nextgeneration microwave receivers.Linear gain and linear dynamic range(LDR)are critical metrics for assessing receiver sensitivity and demodulation fidelity,respectively.We numerically solve the four-level master equation and then employ particle swarm optimization(PSO)algorithm to co-optimize linear gain and LDR in atomic superheterodyne receivers based on balanced homodyne detection.Further,we systematically account for dominant dephasing mechanisms in the simulation,encompassing spontaneous decay,transit dephasing,collision dephasing,laser linewidth dephasing,and Doppler averaging.Homodyne readout utilizes both the real and imaginary parts of polarizability for sensing.In the case of the photon shot noise limit,its signal-to-noise ratio(SNR)expression resembles that of direct optical-intensity readout.However,the inherent coherent subtraction operation in homodyne detection significantly suppresses common-mode noise,while appropriately increasing the reference beam power enhances the gain in practical experiments.Indeed,this co-optimization problem,characterized by a high-dimensional variable space,two objectives,and non-convexity,is well-suited for solution by PSO.In addition,probe and coupling detuning contribute equivalently to polarizability and compensate for each other owing to Doppler averaging,thereby reducing the optimization variable space by one.By adopting a product form of linear gain and LDR as the fitness function,the PSO achieves rapid convergence.Here,the effectiveness of the PSO results is verified via the total harmonic distortion(THD).The relative error-based LDR calculation method we proposed efficiently measures receiver response linearity with consuming fewer computational resources.This research is expected to offer valuable insights into enhancing the performance of Rydberg-atom-based superheterodyne receivers.展开更多
Every year, around the world, between 250,000 and 500,000 people suffer a spinal cord injury(SCI). SCI is a devastating medical condition that arises from trauma or disease-induced damage to the spinal cord, disruptin...Every year, around the world, between 250,000 and 500,000 people suffer a spinal cord injury(SCI). SCI is a devastating medical condition that arises from trauma or disease-induced damage to the spinal cord, disrupting the neural connections that allow communication between the brain and the rest of the body, which results in varying degrees of motor and sensory impairment. Disconnection in the spinal tracts is an irreversible condition owing to the poor capacity for spontaneous axonal regeneration in the affected neurons.展开更多
Objectives This study aimed to evaluate the effectiveness of the stepped self-care program on the self-care,self-efficacy,and quality of life of stroke survivors.Methods This quasi-experimental study allocated 110 str...Objectives This study aimed to evaluate the effectiveness of the stepped self-care program on the self-care,self-efficacy,and quality of life of stroke survivors.Methods This quasi-experimental study allocated 110 stroke survivors from two neurology wards into an intervention group(n=55)who received the stepped self-care program and a control group(n=55)who received usual care from June to December 2023.The Self-Care of Stroke Inventory,Stroke Self-Efficacy Questionnaire,and the short version of the Stroke Specific Quality of Life Scale were administered at baseline(T0),immediately post-intervention(T_(1)),and at 1-month(T_(2))and 3-month(T_(3))follow-ups.Data were analyzed using repeated measures analyses of variance,and generalized estimating equations.Results A total of 48 participants in the intervention group and 50 participants in the control group completed the study.No statistically significant differences were observed at T0 in any of the measured indicators(all P>0.05).The study showed significant group,time,and group×time interaction effects across the assessed outcomes(all P<0.05).Follow-up between-group comparisons at T_(1),T_(2),and T_(3) indicated that the intervention group had significantly higher scores in self-care maintenance,self-care monitoring,self-care management,self-efficacy,and quality of life than the control group(all P<0.001).Conclusions The stepped self-care program significantly improved self-care behaviors,self-efficacy,and quality of life among stroke survivors.These findings support the broader implementation of this approach in post-discharge home self-care.展开更多
To systematically elucidate the central role of the cardiac autonomic nervous system(ANS)in maintaining cardiovascular homeostasis,analyze the pathological mechanisms underlying its dysregulation,integrate multidiscip...To systematically elucidate the central role of the cardiac autonomic nervous system(ANS)in maintaining cardiovascular homeostasis,analyze the pathological mechanisms underlying its dysregulation,integrate multidisciplinary research findings from the U.S.stimulating peripheral nerves to alleviate disease symptoms(SPARC)program,and evaluate the unique advantages and current limitations of acupuncture in modulating cardiac ANS function,ultimately proposing novel strategies for the prevention and treatment of cardiovascular diseases.A systematic literature review was conducted to synthesize current knowledge on the fundamental regulatory mechanisms of the cardiac ANS,the SPARC program's innovative contributions to neuroanatomy and neural pathway mapping,as well as clinical and experimental evidence supporting acupuncture's modulation of the ANS.The SPARC program has made significant progress in elucidating the anatomical organization and neural circuitry of the cardiac ANS through interdisciplinary collaboration,offering novel insights and methodological frameworks for studying cardiac autonomic regulation.Acupuncture,as a cornerstone of traditional medicine,has demonstrated both specificity and multi-target regulatory effects on the cardiac ANS through clinical and experimental studies.However,challenges remain,including an incomplete mechanistic understanding,technical limitations in research methodologies,and difficulties in translating findings into clinical practice.Future research on acupuncture should build upon its inherent strengths while advancing its integration with modern scientific and technological approaches.Strengthening interdisciplinary collaboration and leveraging artificial intelligence can open new frontiers in mechanistic exploration and technological innovation.These efforts will facilitate the internationalization of acupuncture research and contribute innovative perspectives and therapeutic strategies for cardiovascular disease prevention and treatment.展开更多
Knowing the precise relationship between fuel loading and reactivity is essential for guiding reactor criticality extrapolation and online refueling in molten salt reactors(MSRs).This study aims to explore and explain...Knowing the precise relationship between fuel loading and reactivity is essential for guiding reactor criticality extrapolation and online refueling in molten salt reactors(MSRs).This study aims to explore and explain the linear relationship between reactivity and the reciprocal of uranium concentration in thermal-spectrum MSRs.By applying neutron balance theory,we analyzed the neutron absorption cross sections of various nuclides in single-lattice models with varying fuel concentrations.Our findings reveal a simple linear correlation between reactivity and the reciprocal of uranium concentration,which can be explained from the perspective of nuclear reaction cross sections that adhere to the 1/v law in the thermal neutron spectrum.Furthermore,we identified that the neutron absorption single-group cross sections of structural materials and carrier salts exhibit an approximately linear relationship with the fission single-group cross section of ^(235) U;similarly,the reciprocal of ^(235)U’s fission cross section exhibits an approximately linear relationship with uranium concentration.This linear relationship deviates as the volume fraction of molten salt increases,due to a greater proportion of neutrons being captured in the resonance energy spectrum.However,it remains valid for molten salt volume fractions up to 25%and demonstrates broad applicability in the physical design and operation of thermal molten salt reactors.展开更多
This article studies the consensus problem with directed graphs for general linear multi-agent systems.New distributed state-feedback protocols with dynamic event-triggered(DET)mechanisms are proposed for directed gra...This article studies the consensus problem with directed graphs for general linear multi-agent systems.New distributed state-feedback protocols with dynamic event-triggered(DET)mechanisms are proposed for directed graphs that are strongly connected and weight-balanced,general strongly connected,and have spanning trees,respectively.It is proven that strictly positive minimum inter-event times(MIETs)are ensured using the designed DET mechanisms.Several numerical examples are presented to illustrate the effectiveness of the theoretical results.Compared with existing results,our results have the following merits:1)DET mechanisms are designed to determine the sampling instants,which can reduce the communication frequency between agents compared with static mechanisms;2)We focus on the consensus problem on directed graphs,which is more general than existing related results on undirected graphs;3)The existence of positive MIETs is shown to be guaranteed by the designed DET sampling strategies while existing related results can only exclude Zeno behavior.展开更多
Instrumental and expert assessments were used to assess the effect of massage on facial skin blood perfusion,as well as the effects of the long-term use of the two skin health programs on the water content of the stra...Instrumental and expert assessments were used to assess the effect of massage on facial skin blood perfusion,as well as the effects of the long-term use of the two skin health programs on the water content of the stratum corneum,F4,L^(*),dermal and epidermal thickness and density,facial wrinkles,and so on.Sixty healthy Chinese women were selected as the study subjects,which were subsequently divided into G1 non-massage group and G2 massage group.The results show that massage can increase the blood perfusion of facial skin.Group G2 solution is found to be more effective in improving the skin structural barrier(epidermal density),skin elasticity,firmness(dermal thickness)and forehead wrinkles.展开更多
Aiming at the problem of innovative talent training in the industry field in characteristic software colleges,combined with the actual situation of Software College of Northeastern University,this paper analyzes the c...Aiming at the problem of innovative talent training in the industry field in characteristic software colleges,combined with the actual situation of Software College of Northeastern University,this paper analyzes the construction requirements of characteristic talent training mode and training scheme,puts forward the reform of characteristic software innovative talent training scheme integrating production and education,and takes the characteristic direction of financial technology as an example to introduce the curriculum construction based on industry-education integration and school-enterprise cooperation.展开更多
The field of nanomedicine has been revolutionized by the concept of immunogenic cell death(ICD)-enhanced cancer therapy,which holds immense promise for the efficient treatment of cancer.However,precise delivery of ICD...The field of nanomedicine has been revolutionized by the concept of immunogenic cell death(ICD)-enhanced cancer therapy,which holds immense promise for the efficient treatment of cancer.However,precise delivery of ICD inducer is severely hindered by complex biological barriers.How to design and build intelligent nanoplatform for adaptive and dynamic cancer therapy remains a big challenge.Herein,this article presents the design and preparation of CD44-targeting and ZIF-8 gated gold nanocage(Au@ZH) for programmed delivery of the 1,2-diaminocyclohexane-Pt(Ⅱ)(DACHPt) as ICD inducer.After actively targeting the CD44 on the surface of 4T1 tumor cell,this Pt-Au@ZH can be effectively endocytosed by the 4T1 cell and release the DACHPt in tumor acidic environment,resulting in ICD effect and superior antitumor efficacy both in vitro and in vivo in the presence of mild 808 nm laser irradiation.By integration of internal and external stimuli intelligently,this programmed nanoplatform is poised to become a cornerstone in the pursuit of effective and targeted cancer therapy in the foreseeable future.展开更多
NaNbO_(3)-based lead-free dielectric ceramics possess significant application prospects in the field of dielectric capacitors.However,their development is hindered by low recoverable energy storage density(W_(rec))and...NaNbO_(3)-based lead-free dielectric ceramics possess significant application prospects in the field of dielectric capacitors.However,their development is hindered by low recoverable energy storage density(W_(rec))and energy storage efficiency(η).Herein,novel NaNbO_(3)-based ceramics,(1-x)[0.7Na_(0.97)Sm_(0.01)NbO_(3)–0.3(Sr_(0.7)Bi_(0.2))(Ti_(0.8)Zr_(0.2))O_(3)]–xCaTiO_(3),were created by adding CaTiO_(3) linear dielectric,aiming to improve their energy storage performance(ESP).The phase structure,microstructure,dielectric properties,energy storage and charge–discharge performances of the ceramics were methodically analyzed.All components of the ceramics exhibit a perovskite structure consisting of two phases:antiferroelectric P-phase(AFE P)and antiferroelectric R-phase(AFE R),with the AFE R phase increasing as x rises.All ceramic surfaces exhibit clear grain morphology.The resultant ceramics have an appropriate dielectric constant and a small dielectric loss,which are beneficial for improving breakdown field strength(E_(b)).Finally,at an E_(b) of 470 kV/cm,0.85[0.7Na_(0.97)Sm_(0.01)NbO_(3)–0.3(Sr_(0.7)Bi_(0.2))(Ti_(0.8)Zr_(0.2))O_(3)]–0.15CaTiO_(3) ceramic achieves optimal ESP:W_(rec)=3.9 J/cm^(3),η=72.49%.In addition,it has remarkable stability with temperature and frequency in energy storage and displays ultrafast speed in the charge–discharge process(t_(0.9)=27 ns).展开更多
In order to investigate the penetration performance of Linear-Shaped Charge(LSC),Embowed LinearShaped Charge(ELSC),and Embowed Linear Explosively Formed Projectile(ELEFP)on T-shaped stiffened plates,a series of near-f...In order to investigate the penetration performance of Linear-Shaped Charge(LSC),Embowed LinearShaped Charge(ELSC),and Embowed Linear Explosively Formed Projectile(ELEFP)on T-shaped stiffened plates,a series of near-field air-burst experiments are conducted.The damage modes and characteristics of the target plates are compared and analyzed.Each flat plate section is completely punctured,resulting in a penetration hole.The damage modes induced by the three charge types on the stiffened plate structure are consistent,characterized by shear failure in the central region of the flat plate due to penetration by the penetrator,localized plastic deformation of the flat plate,and local penetration failure resulting from partial perforation of the central stiffener.The penetration lengths caused by ELSC and ELEFP are 45.1%and 46.1% larger than that of LSC,while the half-width of the penetration hole generated by ELEFP is 54.2% and 24.7% smaller than that of ELSC and LSC,respectively.The penetration height caused by ELEFP are 17.5%and 62.1% larger than that of ELSC and LSC,respectively.The stiffener effectively segments the damage area,enhancing the local structural strength and limiting the extent of plastic deformation in the flat plate section.The comparative results show that the ELSC proves to be more effective for efficient large-scale damage,and ELEFP is more suitable for achieving efficient localized damage.展开更多
基金Supported by the National Natural Science Foundation of China(Grant Nos.12571317 and 12071133).
文摘In this paper,we study a class of Linear Fractional Programming on a nonempty bounded set,called the Problem(LFP),and design a branch and bound algorithm to find the global optimal solution of the problem(LFP).First,we convert the problem(LFP)to the equivalent problem(EP2).Secondly,by applying the linear relaxation technique to the problem(EP2),the linear relaxation programming problem(LRP2Y)was obtained.Then,the overall framework of the algorithm is given,and the convergence and complexity of the algorithm are analyzed.Finally,experimental results are listed to illustrate the effectiveness of the algorithm.
基金support from the National Natural Science Foundation of China(No.12002372)the Young Elite Scientists Sponsorship Program by China Association for Science and Technology(No.2022QNRC001)the Natural Science Foundation of Hunan Province,China(No.2021JJ40674)。
文摘The operational demands of a wide range significantly exacerbate combustion instability issues within ramjet combustor.To suppress combustion oscillations,an open-loop control system utilizing Linear Genetic Programming(LGP)has been developed for a full-scale annular ramjet combustor.The LGP is used to generate control laws that include multi-frequency forcing.These laws are then transformed into square waves to actuate the solenoid valve,which modulates the kerosene supply for open-loop control.The results show that the duty cycle has little effect on instability amplitude,whereas an increase in frequency leads to a remarked reduction in combustion amplitude.After five generations evolvements,the pressure amplitude is reduced by 40.6% under the optimal control law generated by LGP.Furthermore,the machine learning process is depicted using a proximity map of control law similarity,with the search pathway visualized by the steepest descent.All individuals go forward to the upper left corner of the map with the evolution process,terminating at the optimal individual of the fifth generation.
基金supported by the National Natural Sci‐ence Foundation of China(Grant No.62306325)。
文摘During the use of robotics in applications such as antiterrorism or combat,a motion-constrained pursuer vehicle,such as a Dubins unmanned surface vehicle(USV),must get close enough(within a prescribed zero or positive distance)to a moving target as quickly as possible,resulting in the extended minimum-time intercept problem(EMTIP).Existing research has primarily focused on the zero-distance intercept problem,MTIP,establishing the necessary or sufficient conditions for MTIP optimality,and utilizing analytic algorithms,such as root-finding algorithms,to calculate the optimal solutions.However,these approaches depend heavily on the properties of the analytic algorithm,making them inapplicable when problem settings change,such as in the case of a positive effective range or complicated target motions outside uniform rectilinear motion.In this study,an approach employing a high-accuracy and quality-guaranteed mixed-integer piecewise-linear program(QG-PWL)is proposed for the EMTIP.This program can accommodate different effective interception ranges and complicated target motions(variable velocity or complicated trajectories).The high accuracy and quality guarantees of QG-PWL originate from elegant strategies such as piecewise linearization and other developed operation strategies.The approximate error in the intercept path length is proved to be bounded to h^(2)/(4√2),where h is the piecewise length.
基金supported by China Postdoctoral Science Foundation(No.2020M670469)National Key Research and Development Program of China(No.2019YFB1803303,No.2020YFB1806702).
文摘Linear programming(LP)decoding is a classic decoding method for linear block codes,and has attracted recent researches because its potential in joint channel processing.However,for polar codes,LP decoders has long been outperformed by CRCaided successive cancellation list(CA-SCL)decoders.To increase the competitiveness of 5G NR LP polar decoding,it is possible to gain performance improvements by exploiting the cyclic redundancy check(CRC)setup.In this paper,we propose a combined scheme of reduced sparsified factor graph-sparsified CRC(RSFG-SCRC)and augmented generator matrix-CRC(AGM-CRC),for polytope generation in adaptive linear programming(ALP)decoder for 5G polar codes.Augmented generator matrix(AGM)polytope and improved maximum cycle strategy-auxiliary node pairs 4(MCS-ANP-4)algorithm are proposed,to make efficient use of CRC constraints and minimize the constraint size for the decoder.Numerical simulations show that adaptive linear programming decoders with our proposed RSFG-SCRC and AGM-CRC polytopes can achieve significantly better block error rate(BLER)performance than a benchmark CA-SCL-8 decoder especially in harsh low-to-medium SNR regions.
文摘现有电力负荷预测方法面临诸多挑战,尤其是在考虑气象因素对负荷波动的影响时,传统方法往往忽视气象特征与负荷之间复杂的非线性关系,导致预测精度不足。对此文中提出一种基于气象相似日修正(meteorological similar day correction,MSDC)和改进鹦鹉优化(improved parrot optimizer,IPO)线性分解(decomposition-based linear,DLinear)的日前电力负荷预测模型。首先运用Logistic映射、自适应变异策略、螺旋波动搜索IPO对DLinear超参数进行优化,然后由DLinear提取数据的周期性和趋势性特征,最后通过比对气象特征欧氏距离修正负荷预测值,形成基于IPO-DLinear-MSDC的日前电力负荷预测模型。采用2024年6月至10月湖南株洲地区总电力负荷数据集进行仿真分析,IPO-DLinear-MSDC模型的输出平均绝对百分比误差(mean absolute percentage error,MAPE)、决定系数R2分别为4.67%、0.833,相较于IPO-DLinear与PO-DLinear模型,MAPE分别下降了0.83个百分点、1.43个百分点,R2分别提升了0.074、0.125。
文摘Two new linear furocoumarins were isolated from Notopterygium incisum using silica gel,gel Sephadex LH-20 column chromatography,and preparative high-performance liquid chromatography.The structures of the new compounds were elucidated through analysis of spectroscopic evidence,including data obtained from high-resolution electrospray ionization mass spectrometry(HRESIMS)and nuclear magnetic resonance(NMR).The absolute configurations of Notoprenylate L(1)and Nototerprinol K(2)were further confirmed using electronic circular dichroism(ECD)calculations.Compound 1 demonstrated the ability to inhibit the expression of nitric oxide(NO),a pro-inflammatory factor,in lipopolysaccharide-induced RAW264.7 macrophages at a concentration of 7.5μmol/L,indicating its potential for anti-inflammatory activity.
基金supported by the National Natural Science Foundation of China under Grant No.92582204,No.62577007,and No.62177003the Fundamental Research Funds for the Central Universities under Grant No.JKF-2025011975129.
文摘Online programming platforms are popular in programming education.However,there has been no research investigating students’real opinions and expectations of the error feedback mechanisms,leaving educators without a solid data foundation when attempting to improve the error feedback mechanisms.This paper makes a survey of 834 students across various programming courses and investigates student perceptions of error feedback mechanisms on online programming platforms.It explores the effectiveness of existing feedback,student satisfaction,and preferences for potential improvements,focusing on automatic error localization and program repair mechanisms.Results reveal a significant portion of students are dissatisfied with current feedback due to its limited informativeness.Students also express a clear demand for stronger feedback mechanisms,such as error localization and repair hints.Nevertheless,they prefer feedback that subtly guides them toward solutions,rather than providing direct and explicit answers,valuing the opportunity to enhance their debugging skills.The findings suggest a need for balanced,educational-focused feedback mechanisms that aid learning while promoting independent problem-solving.
基金supported by the National Natural Science Foundation of China(NSFC 52175281,52475315)Youth Innovation Promotion Association of CAS(2021382)。
文摘The growing prevalence of exercise-induced tibial stress fractures demands wearable sensors capable of monitoring dynamic musculoskeletal loads with medical-grade precision.While flexible pressure-sensing insoles show clinical potential,their development has been hindered by the intrinsic trade-off between high sensitivity and full-range linearity(R^(2)>0.99 up to 1 MPa)in conventional designs.Inspired by the tactile sensing mechanism of human skin,where dermal stratification enables wide-range pressure adaptation and ion-channelregulated signaling maintains linear electrical responses,we developed a dual-mechanism flexible iontronic pressure sensor(FIPS).This innovative design synergistically combines two bioinspired components:interdigitated fabric microstructures enabling pressure-proportional contact area expansion(αP1/3)and iontronic film facilitating self-adaptive ion concentration modulation(αP^(2/3)),which together generate a linear capacitance-pressure response(CαP).The FIPS achieves breakthrough performance:242 kPa^(-1)sensitivity with 0.997linearity across 0-1 MPa,yielding a record linear sensing factor(LSF=242,000).The design is validated across various substrates and ionic materials,demonstrating its versatility.Finally,the FIPS-driven design enables a smart insole demonstrating 1.8%error in tibial load assessment during gait analysis,outperforming nonlinear counterparts(6.5%error)in early fracture-risk prediction.The biomimetic design framework establishes a universal approach for developing high-performance linear sensors,establishing generalized principles for medical-grade wearable devices.
基金Project supported by the National Natural Science Foundation of China(Grant Nos.62331024 and 62571549)the National Key Research and Development Program of China(Grant No.2022YFB2802804)。
文摘Rydberg-atom-based superheterodyne receivers integrate self-calibration,high sensitivity,a wide operational frequency range,and phase/frequency resolved detection capabilities,demonstrating broad application prospects as nextgeneration microwave receivers.Linear gain and linear dynamic range(LDR)are critical metrics for assessing receiver sensitivity and demodulation fidelity,respectively.We numerically solve the four-level master equation and then employ particle swarm optimization(PSO)algorithm to co-optimize linear gain and LDR in atomic superheterodyne receivers based on balanced homodyne detection.Further,we systematically account for dominant dephasing mechanisms in the simulation,encompassing spontaneous decay,transit dephasing,collision dephasing,laser linewidth dephasing,and Doppler averaging.Homodyne readout utilizes both the real and imaginary parts of polarizability for sensing.In the case of the photon shot noise limit,its signal-to-noise ratio(SNR)expression resembles that of direct optical-intensity readout.However,the inherent coherent subtraction operation in homodyne detection significantly suppresses common-mode noise,while appropriately increasing the reference beam power enhances the gain in practical experiments.Indeed,this co-optimization problem,characterized by a high-dimensional variable space,two objectives,and non-convexity,is well-suited for solution by PSO.In addition,probe and coupling detuning contribute equivalently to polarizability and compensate for each other owing to Doppler averaging,thereby reducing the optimization variable space by one.By adopting a product form of linear gain and LDR as the fitness function,the PSO achieves rapid convergence.Here,the effectiveness of the PSO results is verified via the total harmonic distortion(THD).The relative error-based LDR calculation method we proposed efficiently measures receiver response linearity with consuming fewer computational resources.This research is expected to offer valuable insights into enhancing the performance of Rydberg-atom-based superheterodyne receivers.
基金financially supported by Ministerio de Ciencia e Innovación projects SAF2017-82736-C2-1-R to MTMFin Universidad Autónoma de Madrid and by Fundación Universidad Francisco de Vitoria to JS+2 种基金a predoctoral scholarship from Fundación Universidad Francisco de Vitoriafinancial support from a 6-month contract from Universidad Autónoma de Madrida 3-month contract from the School of Medicine of Universidad Francisco de Vitoria。
文摘Every year, around the world, between 250,000 and 500,000 people suffer a spinal cord injury(SCI). SCI is a devastating medical condition that arises from trauma or disease-induced damage to the spinal cord, disrupting the neural connections that allow communication between the brain and the rest of the body, which results in varying degrees of motor and sensory impairment. Disconnection in the spinal tracts is an irreversible condition owing to the poor capacity for spontaneous axonal regeneration in the affected neurons.
基金The National Natural Science Foundation of China[72174184]provided policy and financialsupport for this research.
文摘Objectives This study aimed to evaluate the effectiveness of the stepped self-care program on the self-care,self-efficacy,and quality of life of stroke survivors.Methods This quasi-experimental study allocated 110 stroke survivors from two neurology wards into an intervention group(n=55)who received the stepped self-care program and a control group(n=55)who received usual care from June to December 2023.The Self-Care of Stroke Inventory,Stroke Self-Efficacy Questionnaire,and the short version of the Stroke Specific Quality of Life Scale were administered at baseline(T0),immediately post-intervention(T_(1)),and at 1-month(T_(2))and 3-month(T_(3))follow-ups.Data were analyzed using repeated measures analyses of variance,and generalized estimating equations.Results A total of 48 participants in the intervention group and 50 participants in the control group completed the study.No statistically significant differences were observed at T0 in any of the measured indicators(all P>0.05).The study showed significant group,time,and group×time interaction effects across the assessed outcomes(all P<0.05).Follow-up between-group comparisons at T_(1),T_(2),and T_(3) indicated that the intervention group had significantly higher scores in self-care maintenance,self-care monitoring,self-care management,self-efficacy,and quality of life than the control group(all P<0.001).Conclusions The stepped self-care program significantly improved self-care behaviors,self-efficacy,and quality of life among stroke survivors.These findings support the broader implementation of this approach in post-discharge home self-care.
基金supported by the National Natural Science Foundation of China(82174513)Fundamental Research Funds for the Central Public Welfare Research Institutes(ZZ-JQ2023003).
文摘To systematically elucidate the central role of the cardiac autonomic nervous system(ANS)in maintaining cardiovascular homeostasis,analyze the pathological mechanisms underlying its dysregulation,integrate multidisciplinary research findings from the U.S.stimulating peripheral nerves to alleviate disease symptoms(SPARC)program,and evaluate the unique advantages and current limitations of acupuncture in modulating cardiac ANS function,ultimately proposing novel strategies for the prevention and treatment of cardiovascular diseases.A systematic literature review was conducted to synthesize current knowledge on the fundamental regulatory mechanisms of the cardiac ANS,the SPARC program's innovative contributions to neuroanatomy and neural pathway mapping,as well as clinical and experimental evidence supporting acupuncture's modulation of the ANS.The SPARC program has made significant progress in elucidating the anatomical organization and neural circuitry of the cardiac ANS through interdisciplinary collaboration,offering novel insights and methodological frameworks for studying cardiac autonomic regulation.Acupuncture,as a cornerstone of traditional medicine,has demonstrated both specificity and multi-target regulatory effects on the cardiac ANS through clinical and experimental studies.However,challenges remain,including an incomplete mechanistic understanding,technical limitations in research methodologies,and difficulties in translating findings into clinical practice.Future research on acupuncture should build upon its inherent strengths while advancing its integration with modern scientific and technological approaches.Strengthening interdisciplinary collaboration and leveraging artificial intelligence can open new frontiers in mechanistic exploration and technological innovation.These efforts will facilitate the internationalization of acupuncture research and contribute innovative perspectives and therapeutic strategies for cardiovascular disease prevention and treatment.
基金supported by the Youth Innovation Promotion Association of the Chinese Academy of Sciences(No.2020261)the Strategic Priority Research Program of the Chinese Academy of Sciences(No.XDA02010000)the Young Potential Program of the Shanghai Institute of Applied Physics,Chinese Academy of Sciences(No.SINAP-YXJH-202412)。
文摘Knowing the precise relationship between fuel loading and reactivity is essential for guiding reactor criticality extrapolation and online refueling in molten salt reactors(MSRs).This study aims to explore and explain the linear relationship between reactivity and the reciprocal of uranium concentration in thermal-spectrum MSRs.By applying neutron balance theory,we analyzed the neutron absorption cross sections of various nuclides in single-lattice models with varying fuel concentrations.Our findings reveal a simple linear correlation between reactivity and the reciprocal of uranium concentration,which can be explained from the perspective of nuclear reaction cross sections that adhere to the 1/v law in the thermal neutron spectrum.Furthermore,we identified that the neutron absorption single-group cross sections of structural materials and carrier salts exhibit an approximately linear relationship with the fission single-group cross section of ^(235) U;similarly,the reciprocal of ^(235)U’s fission cross section exhibits an approximately linear relationship with uranium concentration.This linear relationship deviates as the volume fraction of molten salt increases,due to a greater proportion of neutrons being captured in the resonance energy spectrum.However,it remains valid for molten salt volume fractions up to 25%and demonstrates broad applicability in the physical design and operation of thermal molten salt reactors.
基金supported in part by the Natural Science Foundation of China(62273227,92367203)the Open Research Project of the State Key Laboratory of Industrial Control Technology,China(ICT2024B68)。
文摘This article studies the consensus problem with directed graphs for general linear multi-agent systems.New distributed state-feedback protocols with dynamic event-triggered(DET)mechanisms are proposed for directed graphs that are strongly connected and weight-balanced,general strongly connected,and have spanning trees,respectively.It is proven that strictly positive minimum inter-event times(MIETs)are ensured using the designed DET mechanisms.Several numerical examples are presented to illustrate the effectiveness of the theoretical results.Compared with existing results,our results have the following merits:1)DET mechanisms are designed to determine the sampling instants,which can reduce the communication frequency between agents compared with static mechanisms;2)We focus on the consensus problem on directed graphs,which is more general than existing related results on undirected graphs;3)The existence of positive MIETs is shown to be guaranteed by the designed DET sampling strategies while existing related results can only exclude Zeno behavior.
文摘Instrumental and expert assessments were used to assess the effect of massage on facial skin blood perfusion,as well as the effects of the long-term use of the two skin health programs on the water content of the stratum corneum,F4,L^(*),dermal and epidermal thickness and density,facial wrinkles,and so on.Sixty healthy Chinese women were selected as the study subjects,which were subsequently divided into G1 non-massage group and G2 massage group.The results show that massage can increase the blood perfusion of facial skin.Group G2 solution is found to be more effective in improving the skin structural barrier(epidermal density),skin elasticity,firmness(dermal thickness)and forehead wrinkles.
文摘Aiming at the problem of innovative talent training in the industry field in characteristic software colleges,combined with the actual situation of Software College of Northeastern University,this paper analyzes the construction requirements of characteristic talent training mode and training scheme,puts forward the reform of characteristic software innovative talent training scheme integrating production and education,and takes the characteristic direction of financial technology as an example to introduce the curriculum construction based on industry-education integration and school-enterprise cooperation.
基金financially supported by the Natural Science Foundation of Jiangsu Province (No.BK20200709)the Natural Science Foundation of China (Nos.62288102,32201127 and 82270113)+2 种基金the Natural Science Foundation of Guangdong Province (No.2023A1515011386)the Natural Science Foundation of the Jiangsu Higher Education Institutes (No.20KJB430031)the startup fund from Nanjing Tech University,and Disciplinary Fund of School of Pharmaceutical Sciences (2024)。
文摘The field of nanomedicine has been revolutionized by the concept of immunogenic cell death(ICD)-enhanced cancer therapy,which holds immense promise for the efficient treatment of cancer.However,precise delivery of ICD inducer is severely hindered by complex biological barriers.How to design and build intelligent nanoplatform for adaptive and dynamic cancer therapy remains a big challenge.Herein,this article presents the design and preparation of CD44-targeting and ZIF-8 gated gold nanocage(Au@ZH) for programmed delivery of the 1,2-diaminocyclohexane-Pt(Ⅱ)(DACHPt) as ICD inducer.After actively targeting the CD44 on the surface of 4T1 tumor cell,this Pt-Au@ZH can be effectively endocytosed by the 4T1 cell and release the DACHPt in tumor acidic environment,resulting in ICD effect and superior antitumor efficacy both in vitro and in vivo in the presence of mild 808 nm laser irradiation.By integration of internal and external stimuli intelligently,this programmed nanoplatform is poised to become a cornerstone in the pursuit of effective and targeted cancer therapy in the foreseeable future.
基金Project supported by the Natural Science Foundation of Anhui Provincial Education Department(Grant No.KJ2019A0054)。
文摘NaNbO_(3)-based lead-free dielectric ceramics possess significant application prospects in the field of dielectric capacitors.However,their development is hindered by low recoverable energy storage density(W_(rec))and energy storage efficiency(η).Herein,novel NaNbO_(3)-based ceramics,(1-x)[0.7Na_(0.97)Sm_(0.01)NbO_(3)–0.3(Sr_(0.7)Bi_(0.2))(Ti_(0.8)Zr_(0.2))O_(3)]–xCaTiO_(3),were created by adding CaTiO_(3) linear dielectric,aiming to improve their energy storage performance(ESP).The phase structure,microstructure,dielectric properties,energy storage and charge–discharge performances of the ceramics were methodically analyzed.All components of the ceramics exhibit a perovskite structure consisting of two phases:antiferroelectric P-phase(AFE P)and antiferroelectric R-phase(AFE R),with the AFE R phase increasing as x rises.All ceramic surfaces exhibit clear grain morphology.The resultant ceramics have an appropriate dielectric constant and a small dielectric loss,which are beneficial for improving breakdown field strength(E_(b)).Finally,at an E_(b) of 470 kV/cm,0.85[0.7Na_(0.97)Sm_(0.01)NbO_(3)–0.3(Sr_(0.7)Bi_(0.2))(Ti_(0.8)Zr_(0.2))O_(3)]–0.15CaTiO_(3) ceramic achieves optimal ESP:W_(rec)=3.9 J/cm^(3),η=72.49%.In addition,it has remarkable stability with temperature and frequency in energy storage and displays ultrafast speed in the charge–discharge process(t_(0.9)=27 ns).
基金supported by the National Natural Science Foundation of China(Grant Nos.52271307,52061135107,52192692,11802025)the Liao Ning Excellent Youth Fund Program(Grant No.2023JH3/10200012)+1 种基金the Liao Ning Revitalization Tal-ents Program(Grant No.XLYC1908027)the Fundamental Research Funds for the Central Universities(Grant Nos.DUT20RC(3)025,DUT20TD108,DUT20LAB308)。
文摘In order to investigate the penetration performance of Linear-Shaped Charge(LSC),Embowed LinearShaped Charge(ELSC),and Embowed Linear Explosively Formed Projectile(ELEFP)on T-shaped stiffened plates,a series of near-field air-burst experiments are conducted.The damage modes and characteristics of the target plates are compared and analyzed.Each flat plate section is completely punctured,resulting in a penetration hole.The damage modes induced by the three charge types on the stiffened plate structure are consistent,characterized by shear failure in the central region of the flat plate due to penetration by the penetrator,localized plastic deformation of the flat plate,and local penetration failure resulting from partial perforation of the central stiffener.The penetration lengths caused by ELSC and ELEFP are 45.1%and 46.1% larger than that of LSC,while the half-width of the penetration hole generated by ELEFP is 54.2% and 24.7% smaller than that of ELSC and LSC,respectively.The penetration height caused by ELEFP are 17.5%and 62.1% larger than that of ELSC and LSC,respectively.The stiffener effectively segments the damage area,enhancing the local structural strength and limiting the extent of plastic deformation in the flat plate section.The comparative results show that the ELSC proves to be more effective for efficient large-scale damage,and ELEFP is more suitable for achieving efficient localized damage.
