We calculate inclusive light vector mesons(ρ,ω,and φ) production in relativistic heavy ion collisions based on the idea of gluon saturation in the color glass condensate(CGC) framework.At high energies,the value of...We calculate inclusive light vector mesons(ρ,ω,and φ) production in relativistic heavy ion collisions based on the idea of gluon saturation in the color glass condensate(CGC) framework.At high energies,the value of saturation momentum becomes larger than the Quantum Chromodynamics(QCD) confinement scale ∧_(QCD),which implies thatα_s(Q_s) <<1.Using the relativistic kinetic theory,we derive the production rate for the light vector mesons produced by gluon-gluon fusion in the k_T-factorization approach.The numerical results indicate that the light vector mesons from the color glass condensate become prominent in p-p,p-Pb,and Pb-Pb collisions at Large Hadron Collider(LHC) energies.展开更多
Glucose molecules are of great significance being one of the most important molecules in metabolic chain.However,due to the small Raman scattering cross-section and weak/non-adsorption on bare metals,accurately obtain...Glucose molecules are of great significance being one of the most important molecules in metabolic chain.However,due to the small Raman scattering cross-section and weak/non-adsorption on bare metals,accurately obtaining their"fingerprint information"remains a huge obstacle.Herein,we developed a tip-enhanced Raman scattering(TERS)technique to address this challenge.Adopting an optical fiber radial vector mode internally illuminates the plasmonic fiber tip to effectively suppress the background noise while generating a strong electric-field enhanced tip hotspot.Furthermore,the tip hotspot approaching the glucose molecules was manipulated via the shear-force feedback to provide more freedom for selecting substrates.Consequently,our TERS technique achieves the visualization of all Raman modes of glucose molecules within spectral window of 400-3200 cm^(-1),which is not achievable through the far-field/surface-enhanced Raman,or the existing TERS techniques.Our TERS technique offers a powerful tool for accurately identifying Raman scattering of molecules,paving the way for biomolecular analysis.展开更多
针对室内可见光定位中非视距信道(Non Line of Sight,NLOS)导致定位精度不足的问题,提出了一种基于动态高斯加权(Dynamic Gaussian Weighted,DGW)接收信号强度指示(Received Signal Strength Indicator,RSSI)和遗传算法(Genetic Algorit...针对室内可见光定位中非视距信道(Non Line of Sight,NLOS)导致定位精度不足的问题,提出了一种基于动态高斯加权(Dynamic Gaussian Weighted,DGW)接收信号强度指示(Received Signal Strength Indicator,RSSI)和遗传算法(Genetic Algorithm,GA)改进支持向量回归(Support Vector Regression,SVR)的室内可见光定位算法。首先,构建指纹库并划分数据集,计算接收器与光源之间的距离动态调整高斯函数的标准差,再结合RSSI信号的波动性进行自适应加权,以减少NLOS对定位的影响。然后,使用GA优化SVR模型的参数,得到最佳定位模型。最后,使用最佳定位模型对加权后的指纹数据进行定位预测。实验结果表明:本算法的平均定位误差为7.1 cm,相较于SVR、SVR-GA等算法降低了21.1%~42.3%,并且能有效降低NLOS的影响、提高室内定位的精度,具有较强的应用前景。展开更多
目的采用4种机器学习算法分别构建结直肠癌患者术前营养不良的临床风险预测模型,探讨其预测价值。方法回顾性收集2023年1月—2024年5月在新疆医科大学附属肿瘤医院胃肠外科就诊的412例结直肠癌患者的术前资料;按7∶3的比例随机分为训练...目的采用4种机器学习算法分别构建结直肠癌患者术前营养不良的临床风险预测模型,探讨其预测价值。方法回顾性收集2023年1月—2024年5月在新疆医科大学附属肿瘤医院胃肠外科就诊的412例结直肠癌患者的术前资料;按7∶3的比例随机分为训练集(n=288)和验证集(n=124),采用单因素分析及二元logistic回归分析筛选出术前营养不良的预测因子;基于逻辑回归(LR)、支持向量机(SVM)、轻量级梯度提升(LightGBM)、多层感知机(MLP)4种机器学习算法分别构建结直肠癌患者术前营养不良风险预测模型,绘制ROC曲线评价4种算法模型预测效能,通过Delong检验比较4种模型的AUC差异。选择最优算法模型,采用校准曲线和临床决策曲线(DCA曲线)进行验证。结果(1)结直肠癌患者术前营养不良发生率为33.7%,年龄、Braden评分是其独立危险因素;(2)训练集中LightGBM算法模型预测结直肠癌患者术前发生营养不良的AUC高于LR、SVM、MLP算法模型(0.941 VS 0.874、0.830、0.831);(3)ROC曲线结果提示,LightGBM算法模型验证集中预测结直肠癌患者术前发生营养不良的AUC为0.926(95%CI:0.882~0.969);校准曲线显示,LightGBM算法模型预测结直肠癌患者术前发生营养不良的曲线与实际发生营养不良一致性良好;DCA曲线结果显示,LightGBM算法模型在阈值概率区间为0.16~0.79可以提供显著临床净收益。结论基于LightGBM算法构建的临床预测模型在预测结直肠癌患者术前发生营养不良中有较高价值,可以为临床人员实施营养管理提供参考。展开更多
We are all taught that there are only two polarizations of light because Maxwell’s equations only support two polarizations. This is mathematically true for the electromagnetic fields, but we have learned since the d...We are all taught that there are only two polarizations of light because Maxwell’s equations only support two polarizations. This is mathematically true for the electromagnetic fields, but we have learned since the days of Maxwell that the “real” electromagnetic field is not the electromagnetic field tensor Fμv (composed of Electric and Magnetic field terms) but rather the electromagnetic vector potential Aμ. When considered carefully, this requires a third polarization of light with very unusual properties. This third polarization of light does not generate electric or magnetic fields but should be detectable by its impact on supercurrents or quantum interference. It is also unavoidable since it automatically appears under Lorentz transformations to different moving frames.展开更多
Light regulates important metabolic processes in microalgal cells, which can further impact the metabolism and the accumulation of biomolecules such as lipids, carbohydrates, and proteins. Different characteristics of...Light regulates important metabolic processes in microalgal cells, which can further impact the metabolism and the accumulation of biomolecules such as lipids, carbohydrates, and proteins. Different characteristics of light have been studied on various strains of the model diatom Phaeodactylum tricornutum, but not on transconjugant cells and information on wild-type strains is still limited. Therefore, we studied the impact of different light characteristics such as spectral quality, light intensity and light shift on the growth, and the composition in lipids and fatty acids of P. tricornutum cells to provide a comprehensive context for future applications. Initially, we tested the impact of spectral quality and light intensity on P. tricornutum transformed with an episomal vector (Ptev), harboring the resistance gene Sh ble. Results indicated that Ptev cells accumulated more biomass and overall lipids in spectral quality Red 1 (R1: 34% > 600 nm > 66%) more effectively as compared to Red 2 (R2: 8% > 600 nm > 92%). It was also detected that cell granularity was higher in R1 as compared to R2. Furthermore, by testing two light intensities 65 μmol·m<sup>-2</sup>·s<sup>-1</sup> and 145 μmol·m<sup>-2</sup>·s<sup>-1</sup> light, it was observed that 145 μmol·m<sup>-2</sup>·s<sup>-1</sup> led to an increase in growth trend, total biomass and lipid content. Combining spectral qualities and light intensities, we show that the lipid accumulation raised by 2.8-fold. Studying the light intensity and spectral quality allowed us to optimize the light conditions to R1 spectral quality and light intensity 145 μmol·m<sup>-2</sup>·s<sup>-1</sup>. These initial results showed that red light R1 at 145 μmol·m<sup>-2</sup>·s<sup>-1</sup> was the best condition for biomass and total lipids accumulation in Ptev cells. Next, we further combined these two-light optimizations with a third light characteristics, i.e. light shift, where the cultures were shifted during the early stationary phase to a different light environment. We studied Red light shift (Rs) to investigate how light condition variations impacted P. tricornutum transconjugants Ptev and with an episomal vector containing the reporter gene YFP (PtYFP). We observed that Rs induced growth and fatty acid eicosapentaenoic acid (EPA) in Ptev as compared to PtYFP. Altogether, the study shows that red light shift of R1 at 145 μmol·m<sup>-2</sup>·s<sup>-1</sup> promoted biomass and total lipids accumulation in Ptev and PtYFP cells. The study provides a comprehensive approach to using different light characteristics with the aim to optimize growth and lipids, as well as to fatty acid production.展开更多
This paper deals with a systematical analysis and an algorithm of attenuation characteristics of a light attenuator combined by n pieces of polarizers （n-LACP） whose extinction ratios are different from each other. ...This paper deals with a systematical analysis and an algorithm of attenuation characteristics of a light attenuator combined by n pieces of polarizers （n-LACP） whose extinction ratios are different from each other. The attenuation ratio expression of a two-LACP is deduced. We find that the monotonic attenuation interval depends on the first polarizer and that the attenuation range depends on the second one. For the three-LACP, a method for obtaining a monotonic attenuation interval is proposed. Moreover, the attenuation ratio expression is demonstrated. Analysis and experiment show that when the initial status of the three-LACP is at the maximum output, if the second or third polarizer rotates alone, the minimum attenuation ratios can reach K2^-1 and K3^-1, respectively, and if the first polarizer rotates, a minimum attenuation ratio of K2^-1K3^-1 can be obtained （K1, K2 and K3 represent the extinction ratios of the three polarizers in turn）. Furthermore, the attenuation ratio expression of n-LACP and the relevant attenuation characteristics are proposed. The minimum attenuation ratio of an n-LACP is （K2K3 ... Kn）-1.展开更多
基金Supported by the National Natural Science Foundation of China under Grant Nos.11465021 and 11065010
文摘We calculate inclusive light vector mesons(ρ,ω,and φ) production in relativistic heavy ion collisions based on the idea of gluon saturation in the color glass condensate(CGC) framework.At high energies,the value of saturation momentum becomes larger than the Quantum Chromodynamics(QCD) confinement scale ∧_(QCD),which implies thatα_s(Q_s) <<1.Using the relativistic kinetic theory,we derive the production rate for the light vector mesons produced by gluon-gluon fusion in the k_T-factorization approach.The numerical results indicate that the light vector mesons from the color glass condensate become prominent in p-p,p-Pb,and Pb-Pb collisions at Large Hadron Collider(LHC) energies.
基金supported by National Natural Science Foundation of China(12374358,91950207)Guangdong Basic and Applied Basic Research Foundation(2024A1515010420).
文摘Glucose molecules are of great significance being one of the most important molecules in metabolic chain.However,due to the small Raman scattering cross-section and weak/non-adsorption on bare metals,accurately obtaining their"fingerprint information"remains a huge obstacle.Herein,we developed a tip-enhanced Raman scattering(TERS)technique to address this challenge.Adopting an optical fiber radial vector mode internally illuminates the plasmonic fiber tip to effectively suppress the background noise while generating a strong electric-field enhanced tip hotspot.Furthermore,the tip hotspot approaching the glucose molecules was manipulated via the shear-force feedback to provide more freedom for selecting substrates.Consequently,our TERS technique achieves the visualization of all Raman modes of glucose molecules within spectral window of 400-3200 cm^(-1),which is not achievable through the far-field/surface-enhanced Raman,or the existing TERS techniques.Our TERS technique offers a powerful tool for accurately identifying Raman scattering of molecules,paving the way for biomolecular analysis.
文摘针对室内可见光定位中非视距信道(Non Line of Sight,NLOS)导致定位精度不足的问题,提出了一种基于动态高斯加权(Dynamic Gaussian Weighted,DGW)接收信号强度指示(Received Signal Strength Indicator,RSSI)和遗传算法(Genetic Algorithm,GA)改进支持向量回归(Support Vector Regression,SVR)的室内可见光定位算法。首先,构建指纹库并划分数据集,计算接收器与光源之间的距离动态调整高斯函数的标准差,再结合RSSI信号的波动性进行自适应加权,以减少NLOS对定位的影响。然后,使用GA优化SVR模型的参数,得到最佳定位模型。最后,使用最佳定位模型对加权后的指纹数据进行定位预测。实验结果表明:本算法的平均定位误差为7.1 cm,相较于SVR、SVR-GA等算法降低了21.1%~42.3%,并且能有效降低NLOS的影响、提高室内定位的精度,具有较强的应用前景。
文摘目的采用4种机器学习算法分别构建结直肠癌患者术前营养不良的临床风险预测模型,探讨其预测价值。方法回顾性收集2023年1月—2024年5月在新疆医科大学附属肿瘤医院胃肠外科就诊的412例结直肠癌患者的术前资料;按7∶3的比例随机分为训练集(n=288)和验证集(n=124),采用单因素分析及二元logistic回归分析筛选出术前营养不良的预测因子;基于逻辑回归(LR)、支持向量机(SVM)、轻量级梯度提升(LightGBM)、多层感知机(MLP)4种机器学习算法分别构建结直肠癌患者术前营养不良风险预测模型,绘制ROC曲线评价4种算法模型预测效能,通过Delong检验比较4种模型的AUC差异。选择最优算法模型,采用校准曲线和临床决策曲线(DCA曲线)进行验证。结果(1)结直肠癌患者术前营养不良发生率为33.7%,年龄、Braden评分是其独立危险因素;(2)训练集中LightGBM算法模型预测结直肠癌患者术前发生营养不良的AUC高于LR、SVM、MLP算法模型(0.941 VS 0.874、0.830、0.831);(3)ROC曲线结果提示,LightGBM算法模型验证集中预测结直肠癌患者术前发生营养不良的AUC为0.926(95%CI:0.882~0.969);校准曲线显示,LightGBM算法模型预测结直肠癌患者术前发生营养不良的曲线与实际发生营养不良一致性良好;DCA曲线结果显示,LightGBM算法模型在阈值概率区间为0.16~0.79可以提供显著临床净收益。结论基于LightGBM算法构建的临床预测模型在预测结直肠癌患者术前发生营养不良中有较高价值,可以为临床人员实施营养管理提供参考。
文摘We are all taught that there are only two polarizations of light because Maxwell’s equations only support two polarizations. This is mathematically true for the electromagnetic fields, but we have learned since the days of Maxwell that the “real” electromagnetic field is not the electromagnetic field tensor Fμv (composed of Electric and Magnetic field terms) but rather the electromagnetic vector potential Aμ. When considered carefully, this requires a third polarization of light with very unusual properties. This third polarization of light does not generate electric or magnetic fields but should be detectable by its impact on supercurrents or quantum interference. It is also unavoidable since it automatically appears under Lorentz transformations to different moving frames.
文摘Light regulates important metabolic processes in microalgal cells, which can further impact the metabolism and the accumulation of biomolecules such as lipids, carbohydrates, and proteins. Different characteristics of light have been studied on various strains of the model diatom Phaeodactylum tricornutum, but not on transconjugant cells and information on wild-type strains is still limited. Therefore, we studied the impact of different light characteristics such as spectral quality, light intensity and light shift on the growth, and the composition in lipids and fatty acids of P. tricornutum cells to provide a comprehensive context for future applications. Initially, we tested the impact of spectral quality and light intensity on P. tricornutum transformed with an episomal vector (Ptev), harboring the resistance gene Sh ble. Results indicated that Ptev cells accumulated more biomass and overall lipids in spectral quality Red 1 (R1: 34% > 600 nm > 66%) more effectively as compared to Red 2 (R2: 8% > 600 nm > 92%). It was also detected that cell granularity was higher in R1 as compared to R2. Furthermore, by testing two light intensities 65 μmol·m<sup>-2</sup>·s<sup>-1</sup> and 145 μmol·m<sup>-2</sup>·s<sup>-1</sup> light, it was observed that 145 μmol·m<sup>-2</sup>·s<sup>-1</sup> led to an increase in growth trend, total biomass and lipid content. Combining spectral qualities and light intensities, we show that the lipid accumulation raised by 2.8-fold. Studying the light intensity and spectral quality allowed us to optimize the light conditions to R1 spectral quality and light intensity 145 μmol·m<sup>-2</sup>·s<sup>-1</sup>. These initial results showed that red light R1 at 145 μmol·m<sup>-2</sup>·s<sup>-1</sup> was the best condition for biomass and total lipids accumulation in Ptev cells. Next, we further combined these two-light optimizations with a third light characteristics, i.e. light shift, where the cultures were shifted during the early stationary phase to a different light environment. We studied Red light shift (Rs) to investigate how light condition variations impacted P. tricornutum transconjugants Ptev and with an episomal vector containing the reporter gene YFP (PtYFP). We observed that Rs induced growth and fatty acid eicosapentaenoic acid (EPA) in Ptev as compared to PtYFP. Altogether, the study shows that red light shift of R1 at 145 μmol·m<sup>-2</sup>·s<sup>-1</sup> promoted biomass and total lipids accumulation in Ptev and PtYFP cells. The study provides a comprehensive approach to using different light characteristics with the aim to optimize growth and lipids, as well as to fatty acid production.
基金Project supported by the Technological Innovation Project of Air-to-Air Missile Institute of China (Grant No.5S85000FS)
文摘This paper deals with a systematical analysis and an algorithm of attenuation characteristics of a light attenuator combined by n pieces of polarizers （n-LACP） whose extinction ratios are different from each other. The attenuation ratio expression of a two-LACP is deduced. We find that the monotonic attenuation interval depends on the first polarizer and that the attenuation range depends on the second one. For the three-LACP, a method for obtaining a monotonic attenuation interval is proposed. Moreover, the attenuation ratio expression is demonstrated. Analysis and experiment show that when the initial status of the three-LACP is at the maximum output, if the second or third polarizer rotates alone, the minimum attenuation ratios can reach K2^-1 and K3^-1, respectively, and if the first polarizer rotates, a minimum attenuation ratio of K2^-1K3^-1 can be obtained （K1, K2 and K3 represent the extinction ratios of the three polarizers in turn）. Furthermore, the attenuation ratio expression of n-LACP and the relevant attenuation characteristics are proposed. The minimum attenuation ratio of an n-LACP is （K2K3 ... Kn）-1.
