The association between miRNA and disease has attracted more and more attention.Until now,existing methods for identifying miRNA related disease mainly rely on top-ranked association model,which may not provide a full...The association between miRNA and disease has attracted more and more attention.Until now,existing methods for identifying miRNA related disease mainly rely on top-ranked association model,which may not provide a full landscape of association between miRNA and disease.Hence there is strong need of new computational method to identify the associations from miRNA group view.In this paper,we proposed a framework,MDA-TOEPGA,to identify miRNAdisease association based on two-objective evolutionary programming genetic algorithm,which identifies latent miRNAdisease associations from the view of functional module.To understand the miRNA functional module in diseases,the case study is presented.We have been compared MDA-TOEPGA with several state-of-the-art functional module algorithm.Experimental results showed that our method cannot only outperform classical algorithms,such as K-means,IK-means,MCODE,HC-PIN,and ClusterONE,but can also achieve an ideal overall performance in terms of a composite score consisting of f1,Sensitivity,and Accuracy.Altogether,our study showed that MDA-TOEPGA is a promising method to investigate miRNA-disease association from the landscapes of functional module.展开更多
Frequency sampling is one of the popular methods in FIR digital filter design. In the frequency sampling method the value of transition band samples, which are usually obtained by consulting a table, must be determi...Frequency sampling is one of the popular methods in FIR digital filter design. In the frequency sampling method the value of transition band samples, which are usually obtained by consulting a table, must be determined in order to make the attenuation within the stopband maximal. However, the value obtained by searching for table can not be ensured to be optimal. Evolutionary programming (EP), a multi agent stochastic optimization technique, can lead to global optimal solutions for complex problems. In this paper a new application of EP to frequency sampling method is introduced. Two examples of lowpass and bandpass FIR filters are presented, and the steps of EP realization and experimental results are given. Experimental results show that the value of transition band samples obtained by EP can be ensured to be optimal and the performance of the filter is improved.展开更多
In this paper, an improved radial basis function networks named hidden neuron modifiable radial basis function (HNMRBF) networks is proposed for target classification, and evolutionary programming (EP) is used as a le...In this paper, an improved radial basis function networks named hidden neuron modifiable radial basis function (HNMRBF) networks is proposed for target classification, and evolutionary programming (EP) is used as a learning algorithm to determine and modify the hidden neuron of HNMRBF nets. The result of passive sonar target classification shows that HNMRBF nets can effectively solve the problem of traditional neural networks, i. e. learning new target patterns on line will cause forgetting of the old patterns.展开更多
Optimal trajectory planning for robot manipulators plays an important role in implementing the high productivity for robots. The performance indexes used in optimal trajectory planning are classified into two main cat...Optimal trajectory planning for robot manipulators plays an important role in implementing the high productivity for robots. The performance indexes used in optimal trajectory planning are classified into two main categories: optimum traveling time and optimum mechanical energy of the actuators. The current trajectory planning algorithms are designed based on one of the above two performance indexes. So far, there have been few planning algorithms designed to satisfy two performance indexes simultaneously. On the other hand, some deficiencies arise in the existing integrated optimi2ation algorithms of trajectory planning. In order to overcome those deficiencies, the integrated optimization algorithms of trajectory planning are presented based on the complete analysis for trajectory planning of robot manipulators. In the algorithm, two object functions are designed based on the specific weight coefficient method and ' ideal point strategy. Moreover, based on the features of optimization problem, the intensified evolutionary programming is proposed to solve the corresponding optimization model. Especially, for the Stanford Robot,the high-quality solutions are found at a lower cost.展开更多
An evolutionary programming based algorithm was proposed for color image quantization. A novel hybrid mutation operator was disigned to improve the quantization quality, and a stochastic sampling scheme was also prese...An evolutionary programming based algorithm was proposed for color image quantization. A novel hybrid mutation operator was disigned to improve the quantization quality, and a stochastic sampling scheme was also presented for saving the run time. The experimental results demonstrate the superior performance of the proposed algorithm in comparison with the GA based algorithm.展开更多
With an aim to the fact that the K-means clustering algorithm usually ends in local optimization and is hard to harvest global optimization, a new web clustering method is presented based on the chaotic social evoluti...With an aim to the fact that the K-means clustering algorithm usually ends in local optimization and is hard to harvest global optimization, a new web clustering method is presented based on the chaotic social evolutionary programming （CSEP） algorithm. This method brings up the manner of that a cognitive agent inherits a paradigm in clustering to enable the cognitive agent to acquire a chaotic mutation operator in the betrayal. As proven in the experiment, this method can not only effectively increase web clustering efficiency, but it can also practically improve the precision of web clustering.展开更多
In many areas, reliability of the digital circuits has become the key factor to restrict circuit development. Fault-tolerant design is the commonly used method to improve the reliability of digital circuits. The curre...In many areas, reliability of the digital circuits has become the key factor to restrict circuit development. Fault-tolerant design is the commonly used method to improve the reliability of digital circuits. The current fault-tolerant design methods are based on triple modular redundancy( TMR) or multiple modular redundancy( MMR). These redundancy designs rely on the experience of the designers,and the designed circuits have poor adaptabilities to a complex environment. However, evolutionary design of digital circuits does not rely on prior knowledge. During the evolution, some novel and optimal circuit topologies can be found, and the evolved circuits can feature strong adaptive capacities. Based on Cartesian genetic programming( CGP), a novel method for designing fault-tolerant digital circuits by evolution is proposed,key steps of the evolution are introduced,influences of function sets on evolution are investigated,and as a preliminary result,an evolved full adder with high fault-tolerance is shown.展开更多
Joint inversion of different potentials improves subsurface model resolution. In this paper seismic refraction and magnetotelluric data are used to understand near subsurface features of Dholera, Gujarat, India. An ex...Joint inversion of different potentials improves subsurface model resolution. In this paper seismic refraction and magnetotelluric data are used to understand near subsurface features of Dholera, Gujarat, India. An extensive seismic and magnetotelluric survey was carried out in Dholera in order to delineate subsurface presence of aquifers. Ray Inversion for Near Surface Estimation (RINSE) is used for inversion of Dholera seismic data. The inversion output of seismic data is used as seed points for resistivity inversion of anomalies. Inversion of resistivity data is done using evolutionary programing method which is also a type of genetic algorithm. Here the optimization is done using four major steps, of evolutionary programing namely population generation, fitness function, crossover and mutation. This paper also compares the similarities between the natural and geophysical optimization. A Low Velocity Layer is identified up to a depth of 11 m from seismic refraction method. Three layers are identified after the interpretation of seismic and resistivity data. The average thicknesses of Layers one and two are calculated as 3.558 and 6.533 respectively.展开更多
In this paper, we focus on a class of nonlinear bilevel programming problems where the follower’s objective is a function of the linear expression of all variables, and the follower’s constraint functions are convex...In this paper, we focus on a class of nonlinear bilevel programming problems where the follower’s objective is a function of the linear expression of all variables, and the follower’s constraint functions are convex with respect to the follower’s variables. First, based on the features of the follower’s problem, we give a new decomposition scheme by which the follower’s optimal solution can be obtained easily. Then, to solve efficiently this class of problems by using evolutionary algorithm, novel evolutionary operators are designed by considering the best individuals and the diversity of individuals in the populations. Finally, based on these techniques, a new evolutionary algorithm is proposed. The numerical results on 20 test problems illustrate that the proposed algorithm is efficient and stable.展开更多
In a multi-agent system, each agent must adapt itself to the environment and coordinate with other agents dynamically. TO predict or cooperate with the behavior of oiller agents. An agent should dynamically establish ...In a multi-agent system, each agent must adapt itself to the environment and coordinate with other agents dynamically. TO predict or cooperate with the behavior of oiller agents. An agent should dynamically establish and evolve the cooperative behavior model of itself. In this paper, we represent the behavior model of an agent as a f-mite state machine and propose a new method of dynamically evolving the behavior model of an agent by evolutionary programming.展开更多
This paper is trying to make some improvement to Markowitz＇s Mean-Variance Model. In this paper, we try to solve the model of portfolio by using Evolutionary Programming under the condition of the covariance matrix w...This paper is trying to make some improvement to Markowitz＇s Mean-Variance Model. In this paper, we try to solve the model of portfolio by using Evolutionary Programming under the condition of the covariance matrix which is a non-positive matrix, and design a new method which can improve Markowitz＇s model. At last, we give an illustrative example with the new method.展开更多
Co-ordination of directional over current relays(DOCR) requires the selection and setting of relays so as to sequentially isolate only that portion of the power system where an abnormality has occurred.The problem of ...Co-ordination of directional over current relays(DOCR) requires the selection and setting of relays so as to sequentially isolate only that portion of the power system where an abnormality has occurred.The problem of coordinating protective relays in electrical power systems consists of selecting suitable settings such that their fundamental protective function is met,given operational requirements of sensitivity,selectivity,reliability and speed.Directional over current relays are best suited for protection of an interconnected sub-station transmission system.One of the major problems associated with this type of protection is the difficulty in coordinating relays.To insure proper coordination,all the main/back up relay pairs must be determined.This paper presents an effective algorithm to determine the minimum number of break points and main/back up relay pairs using relative sequence matrix(RSM).A novel optimization technique based on evolutionary programming was developed using these main/back up relay pairs for directional over current relay coordination in multi-loop networks.Since the problem has multi-optimum points,conventional mathematics based optimization techniques may sometimes fail.Hence evolutionary programming(EP) was used,as it is a stochastic multi-point search optimization algorithm capable of escaping from the local optimum problem,giving a better chance of reaching a global optimum.The method developed was tested on an existing 6 bus,7 line system and better results were obtained than with conventional methods.展开更多
基金This work was supported in part by the National Natural Science Foundation of China under Grants 61873089,62032007the Key Project of the Education Department of Hunan Province under Grant 20A087the Innovation Platform Open Fund Project of Hunan Provincial Education Department under Grant 20K025.
文摘The association between miRNA and disease has attracted more and more attention.Until now,existing methods for identifying miRNA related disease mainly rely on top-ranked association model,which may not provide a full landscape of association between miRNA and disease.Hence there is strong need of new computational method to identify the associations from miRNA group view.In this paper,we proposed a framework,MDA-TOEPGA,to identify miRNAdisease association based on two-objective evolutionary programming genetic algorithm,which identifies latent miRNAdisease associations from the view of functional module.To understand the miRNA functional module in diseases,the case study is presented.We have been compared MDA-TOEPGA with several state-of-the-art functional module algorithm.Experimental results showed that our method cannot only outperform classical algorithms,such as K-means,IK-means,MCODE,HC-PIN,and ClusterONE,but can also achieve an ideal overall performance in terms of a composite score consisting of f1,Sensitivity,and Accuracy.Altogether,our study showed that MDA-TOEPGA is a promising method to investigate miRNA-disease association from the landscapes of functional module.
文摘Frequency sampling is one of the popular methods in FIR digital filter design. In the frequency sampling method the value of transition band samples, which are usually obtained by consulting a table, must be determined in order to make the attenuation within the stopband maximal. However, the value obtained by searching for table can not be ensured to be optimal. Evolutionary programming (EP), a multi agent stochastic optimization technique, can lead to global optimal solutions for complex problems. In this paper a new application of EP to frequency sampling method is introduced. Two examples of lowpass and bandpass FIR filters are presented, and the steps of EP realization and experimental results are given. Experimental results show that the value of transition band samples obtained by EP can be ensured to be optimal and the performance of the filter is improved.
文摘In this paper, an improved radial basis function networks named hidden neuron modifiable radial basis function (HNMRBF) networks is proposed for target classification, and evolutionary programming (EP) is used as a learning algorithm to determine and modify the hidden neuron of HNMRBF nets. The result of passive sonar target classification shows that HNMRBF nets can effectively solve the problem of traditional neural networks, i. e. learning new target patterns on line will cause forgetting of the old patterns.
基金This work was supported in part by National Natural Science Foundation of China (No. 69975003) and Foundation for Dissertation of Ph. D. Candidate of Central South University (No.030618) .
文摘Optimal trajectory planning for robot manipulators plays an important role in implementing the high productivity for robots. The performance indexes used in optimal trajectory planning are classified into two main categories: optimum traveling time and optimum mechanical energy of the actuators. The current trajectory planning algorithms are designed based on one of the above two performance indexes. So far, there have been few planning algorithms designed to satisfy two performance indexes simultaneously. On the other hand, some deficiencies arise in the existing integrated optimi2ation algorithms of trajectory planning. In order to overcome those deficiencies, the integrated optimization algorithms of trajectory planning are presented based on the complete analysis for trajectory planning of robot manipulators. In the algorithm, two object functions are designed based on the specific weight coefficient method and ' ideal point strategy. Moreover, based on the features of optimization problem, the intensified evolutionary programming is proposed to solve the corresponding optimization model. Especially, for the Stanford Robot,the high-quality solutions are found at a lower cost.
文摘An evolutionary programming based algorithm was proposed for color image quantization. A novel hybrid mutation operator was disigned to improve the quantization quality, and a stochastic sampling scheme was also presented for saving the run time. The experimental results demonstrate the superior performance of the proposed algorithm in comparison with the GA based algorithm.
文摘With an aim to the fact that the K-means clustering algorithm usually ends in local optimization and is hard to harvest global optimization, a new web clustering method is presented based on the chaotic social evolutionary programming （CSEP） algorithm. This method brings up the manner of that a cognitive agent inherits a paradigm in clustering to enable the cognitive agent to acquire a chaotic mutation operator in the betrayal. As proven in the experiment, this method can not only effectively increase web clustering efficiency, but it can also practically improve the precision of web clustering.
基金National Natural Science Foundations of China(Nos.61271153,61372039)
文摘In many areas, reliability of the digital circuits has become the key factor to restrict circuit development. Fault-tolerant design is the commonly used method to improve the reliability of digital circuits. The current fault-tolerant design methods are based on triple modular redundancy( TMR) or multiple modular redundancy( MMR). These redundancy designs rely on the experience of the designers,and the designed circuits have poor adaptabilities to a complex environment. However, evolutionary design of digital circuits does not rely on prior knowledge. During the evolution, some novel and optimal circuit topologies can be found, and the evolved circuits can feature strong adaptive capacities. Based on Cartesian genetic programming( CGP), a novel method for designing fault-tolerant digital circuits by evolution is proposed,key steps of the evolution are introduced,influences of function sets on evolution are investigated,and as a preliminary result,an evolved full adder with high fault-tolerance is shown.
文摘Joint inversion of different potentials improves subsurface model resolution. In this paper seismic refraction and magnetotelluric data are used to understand near subsurface features of Dholera, Gujarat, India. An extensive seismic and magnetotelluric survey was carried out in Dholera in order to delineate subsurface presence of aquifers. Ray Inversion for Near Surface Estimation (RINSE) is used for inversion of Dholera seismic data. The inversion output of seismic data is used as seed points for resistivity inversion of anomalies. Inversion of resistivity data is done using evolutionary programing method which is also a type of genetic algorithm. Here the optimization is done using four major steps, of evolutionary programing namely population generation, fitness function, crossover and mutation. This paper also compares the similarities between the natural and geophysical optimization. A Low Velocity Layer is identified up to a depth of 11 m from seismic refraction method. Three layers are identified after the interpretation of seismic and resistivity data. The average thicknesses of Layers one and two are calculated as 3.558 and 6.533 respectively.
文摘In this paper, we focus on a class of nonlinear bilevel programming problems where the follower’s objective is a function of the linear expression of all variables, and the follower’s constraint functions are convex with respect to the follower’s variables. First, based on the features of the follower’s problem, we give a new decomposition scheme by which the follower’s optimal solution can be obtained easily. Then, to solve efficiently this class of problems by using evolutionary algorithm, novel evolutionary operators are designed by considering the best individuals and the diversity of individuals in the populations. Finally, based on these techniques, a new evolutionary algorithm is proposed. The numerical results on 20 test problems illustrate that the proposed algorithm is efficient and stable.
文摘In a multi-agent system, each agent must adapt itself to the environment and coordinate with other agents dynamically. TO predict or cooperate with the behavior of oiller agents. An agent should dynamically establish and evolve the cooperative behavior model of itself. In this paper, we represent the behavior model of an agent as a f-mite state machine and propose a new method of dynamically evolving the behavior model of an agent by evolutionary programming.
文摘This paper is trying to make some improvement to Markowitz＇s Mean-Variance Model. In this paper, we try to solve the model of portfolio by using Evolutionary Programming under the condition of the covariance matrix which is a non-positive matrix, and design a new method which can improve Markowitz＇s model. At last, we give an illustrative example with the new method.
文摘Co-ordination of directional over current relays(DOCR) requires the selection and setting of relays so as to sequentially isolate only that portion of the power system where an abnormality has occurred.The problem of coordinating protective relays in electrical power systems consists of selecting suitable settings such that their fundamental protective function is met,given operational requirements of sensitivity,selectivity,reliability and speed.Directional over current relays are best suited for protection of an interconnected sub-station transmission system.One of the major problems associated with this type of protection is the difficulty in coordinating relays.To insure proper coordination,all the main/back up relay pairs must be determined.This paper presents an effective algorithm to determine the minimum number of break points and main/back up relay pairs using relative sequence matrix(RSM).A novel optimization technique based on evolutionary programming was developed using these main/back up relay pairs for directional over current relay coordination in multi-loop networks.Since the problem has multi-optimum points,conventional mathematics based optimization techniques may sometimes fail.Hence evolutionary programming(EP) was used,as it is a stochastic multi-point search optimization algorithm capable of escaping from the local optimum problem,giving a better chance of reaching a global optimum.The method developed was tested on an existing 6 bus,7 line system and better results were obtained than with conventional methods.
基金国家重点基础研究发展规划(973)(the National Grand Fundamental Research 973 Program of China under Grant No.2004CB318103)国家自然科学基金(the National Natural Science Foundation of China under Grant No.60133010)江西省研究生创新基金项目(No YC07A073)
