In order to explore the pharmacological effects of active components of Gastrodiae Rhizoma on the central nervous system,through consulting related literatures,this paper summarized the pharmacological effects of the ...In order to explore the pharmacological effects of active components of Gastrodiae Rhizoma on the central nervous system,through consulting related literatures,this paper summarized the pharmacological effects of the active components of Gastrodiae Rhizoma.The pharmacological effects of the active components of Gastrodiae Rhizoma on the central nervous system include improving the ability of learning and memory,analgesia,sedation and hypnosis,anticonvulsant,anti-aging,anti-anxiety and neuroprotective effects.The active components of Gastrodiae Rhizoma have certain curative effect in the treatment of some diseases of the central nervous system.At present,it has been widely used clinically.There are no toxic and side effects at conventional doses,and it is worth popularizing and applying.展开更多
The G. Abu Garadi area is covered mainly by metasediments, alkali feldspar granites and stream sediments. The alkali feldspar granite is traversed by a major strike-slip fault trending in an N-S direction as well as t...The G. Abu Garadi area is covered mainly by metasediments, alkali feldspar granites and stream sediments. The alkali feldspar granite is traversed by a major strike-slip fault trending in an N-S direction as well as two subordinate sets of faults trending NW to WNW for the first one and NE for the second one. These faults represent the shear zones affected by magmatic (syngenetic) as well as hydrothermal (epigenetic) activities causing alteration of the granitic rocks. The most common alteration features are albitization, greisenization and koalinitization. The mass balance calculations of the studied altered samples show enrichments in Zr, Y, Ni, U, Th and Ga and depletions in Zn, Sr, Nb, Ba, Pb, Cu and V. Only the greisenized samples exhibit a significant enrichment in Nb, ∑REE budget and pronounced lanthanide tetrad effect (M-type), especially TE1,4, while weakly expressed tetrad effects are for the other albitized and koalinitized samples. Mineralogically, the common accessory minerals in the altered samples include samarskite-(Y), betafite, uranothorite, zircon, fluorite and cassiterite. The greisenized granites contain high eU and eTh than the other altered types, where they are characterized by an assemblage of the radioactive minerals; samarskite-(Y), betafite, uranothorite in addition to zircon. The inter-element relationships between U and Th and also their ratios illustrate that the radioelement distribution in these granites is mainly governed by magmatic processes, in addition to post-magmatic ones. The distribution of chemical elements and the fractionation of some isovalents within the shear zone are largely controlled by the newly formed mineral phases. With respect to uranium mobilization, uranium migrated from the host alkali feldspar granites of G. Abu Garadi, while the shear zones acted as traps for the migrated uranium. Moreover, U migrated in the shear zone during greisenization and albitization, and migrated out during koalinitization.展开更多
We present an energy-based method to estimate centrality in electrical networks. Here the energy between a pair of vertices denotes by the effective resistance between them. If there is only one generation and one loa...We present an energy-based method to estimate centrality in electrical networks. Here the energy between a pair of vertices denotes by the effective resistance between them. If there is only one generation and one load, then the centrality of an edge in our method is the difference between the energy of network after deleting the edge and that of the original network. Compared with the local current-flow betweenness on the IEEE 14-bus system, we have an interesting discovery that our proposed centrality is closely related to it in the sense of that the significance of edges under the two measures are very similar.展开更多
By using the recent spatially dependent nuclear PDF set EPS09 s, we investigated the centrality-dependent Cold Nuclear Matter(CNM) effects for neutral π, η mesons and inclusive jets at RHIC in d+Au collisions and at...By using the recent spatially dependent nuclear PDF set EPS09 s, we investigated the centrality-dependent Cold Nuclear Matter(CNM) effects for neutral π, η mesons and inclusive jets at RHIC in d+Au collisions and at LHC in p+Pb collisions. The nuclear modification factors as functions of transverse momentum are plotted at different centralities bins respectively. At all fixed centralities, the nuclear modification factors show no significant suppressions,contrast to the strong suppressions observed for central Au+Au collisions. Our results are consistent with the PHENIX preliminary Data in minimum bias and central d+Au collisions. The LHC experimental Data also support our predictions for both single inclusive hadron and inclusive jets productions in central p+Pb collisions. And the centrality dependence of the nuclear suppressions for all the observations in our calculations are lower than the RHIC and LHC Data.展开更多
The purpose of this study was to evaluate the acute toxicity and sedative effect of the ethylic extract of Thymelaea lythroides (Tl) on Wistar rats. The study was based on the gavage administration of the ethylic extr...The purpose of this study was to evaluate the acute toxicity and sedative effect of the ethylic extract of Thymelaea lythroides (Tl) on Wistar rats. The study was based on the gavage administration of the ethylic extract of Tl with different doses (i.e. 200, 400, 500 and 5000 mg/kg), where the toxicity and the sedative activity of the plant were observed and the obtained results were analyzed using the ANOVA test followed by the Bonferroni test. The main results of this study showed that the lethal dose of the ethylic extract of Tl was higher than the 5000 mg/kg dose. Moreover, when compared to the control rats, the animals treated with 5000 mg/kg of the extract exhibited significant reduction in appetite for food and water in the first week. Furthermore, results of the psychotropic test conducted during this study showed visible effects on the exploratory activity of the rats. The dose of 5000 mg/kg was also found to have a significant central nervous system effect;the locomotor activities of the animals decreased in a manner similar to those administered with Zepam as control.展开更多
基金Supported by Innovation Team Project for Natural Science Foundation of Guangxi(2011GXNSFF018006)Program of Collaborative Innovation Center of Zhuang and Yao Medicine(Gui Jiao Ke Yan:2013 No.20)+6 种基金Key Discipline of Guangxi(Zhuang Medicine Discipline)(Gui Jiao Ke Yan:2013.No.16)Program of Key Laboratory of Zhuang and Yao Medicine(Gui Ke Ji Zi:2014 No.32)Bagui Scholar Program"Study on Innovation Theory and Efficacy of Traditional Chinese Medicine"Preparation of a New Drug Huotanmu Capsule for the Treatment of Hepatitis B(Nan Ke Fa[2018]No.11)Study on Quality Evaluation and Standard of Gynura divaricate(MZY2017001)Study on Quality Evaluation and Standards of Christia vespertilionis(MZY2017001)Study on Quality Evaluation and Standards of Viola japonica(MZY2017001).
文摘In order to explore the pharmacological effects of active components of Gastrodiae Rhizoma on the central nervous system,through consulting related literatures,this paper summarized the pharmacological effects of the active components of Gastrodiae Rhizoma.The pharmacological effects of the active components of Gastrodiae Rhizoma on the central nervous system include improving the ability of learning and memory,analgesia,sedation and hypnosis,anticonvulsant,anti-aging,anti-anxiety and neuroprotective effects.The active components of Gastrodiae Rhizoma have certain curative effect in the treatment of some diseases of the central nervous system.At present,it has been widely used clinically.There are no toxic and side effects at conventional doses,and it is worth popularizing and applying.
文摘The G. Abu Garadi area is covered mainly by metasediments, alkali feldspar granites and stream sediments. The alkali feldspar granite is traversed by a major strike-slip fault trending in an N-S direction as well as two subordinate sets of faults trending NW to WNW for the first one and NE for the second one. These faults represent the shear zones affected by magmatic (syngenetic) as well as hydrothermal (epigenetic) activities causing alteration of the granitic rocks. The most common alteration features are albitization, greisenization and koalinitization. The mass balance calculations of the studied altered samples show enrichments in Zr, Y, Ni, U, Th and Ga and depletions in Zn, Sr, Nb, Ba, Pb, Cu and V. Only the greisenized samples exhibit a significant enrichment in Nb, ∑REE budget and pronounced lanthanide tetrad effect (M-type), especially TE1,4, while weakly expressed tetrad effects are for the other albitized and koalinitized samples. Mineralogically, the common accessory minerals in the altered samples include samarskite-(Y), betafite, uranothorite, zircon, fluorite and cassiterite. The greisenized granites contain high eU and eTh than the other altered types, where they are characterized by an assemblage of the radioactive minerals; samarskite-(Y), betafite, uranothorite in addition to zircon. The inter-element relationships between U and Th and also their ratios illustrate that the radioelement distribution in these granites is mainly governed by magmatic processes, in addition to post-magmatic ones. The distribution of chemical elements and the fractionation of some isovalents within the shear zone are largely controlled by the newly formed mineral phases. With respect to uranium mobilization, uranium migrated from the host alkali feldspar granites of G. Abu Garadi, while the shear zones acted as traps for the migrated uranium. Moreover, U migrated in the shear zone during greisenization and albitization, and migrated out during koalinitization.
文摘We present an energy-based method to estimate centrality in electrical networks. Here the energy between a pair of vertices denotes by the effective resistance between them. If there is only one generation and one load, then the centrality of an edge in our method is the difference between the energy of network after deleting the edge and that of the original network. Compared with the local current-flow betweenness on the IEEE 14-bus system, we have an interesting discovery that our proposed centrality is closely related to it in the sense of that the significance of edges under the two measures are very similar.
基金Supported by Ministry of Science and Technology in China under Grant Nos.2014CB845404,2014DFG02050by Natural Science Foundation of China under Grant Nos.11322546,11435004,11221504
文摘By using the recent spatially dependent nuclear PDF set EPS09 s, we investigated the centrality-dependent Cold Nuclear Matter(CNM) effects for neutral π, η mesons and inclusive jets at RHIC in d+Au collisions and at LHC in p+Pb collisions. The nuclear modification factors as functions of transverse momentum are plotted at different centralities bins respectively. At all fixed centralities, the nuclear modification factors show no significant suppressions,contrast to the strong suppressions observed for central Au+Au collisions. Our results are consistent with the PHENIX preliminary Data in minimum bias and central d+Au collisions. The LHC experimental Data also support our predictions for both single inclusive hadron and inclusive jets productions in central p+Pb collisions. And the centrality dependence of the nuclear suppressions for all the observations in our calculations are lower than the RHIC and LHC Data.
文摘The purpose of this study was to evaluate the acute toxicity and sedative effect of the ethylic extract of Thymelaea lythroides (Tl) on Wistar rats. The study was based on the gavage administration of the ethylic extract of Tl with different doses (i.e. 200, 400, 500 and 5000 mg/kg), where the toxicity and the sedative activity of the plant were observed and the obtained results were analyzed using the ANOVA test followed by the Bonferroni test. The main results of this study showed that the lethal dose of the ethylic extract of Tl was higher than the 5000 mg/kg dose. Moreover, when compared to the control rats, the animals treated with 5000 mg/kg of the extract exhibited significant reduction in appetite for food and water in the first week. Furthermore, results of the psychotropic test conducted during this study showed visible effects on the exploratory activity of the rats. The dose of 5000 mg/kg was also found to have a significant central nervous system effect;the locomotor activities of the animals decreased in a manner similar to those administered with Zepam as control.
