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Fabrication of Electrospun PVDF Nanofibers with Higher Content of Polar β Phase and Smaller Diameter by Adding a Small Amount of Dioctadecyl Dimethyl Ammonium Chloride
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作者 wei xue cong lv +2 位作者 yao jing 陈枫 傅强 《Chinese Journal of Polymer Science》 SCIE CAS CSCD 2017年第8期992-1000,共9页
In this work,the effect of dioctadecyl dimethyl ammonium chloride(DDAC,a kind of alkyl ammonium salt) on polar β phase content and the diameter of electrospun PVDF nanofibers was investigated for the first time.Our... In this work,the effect of dioctadecyl dimethyl ammonium chloride(DDAC,a kind of alkyl ammonium salt) on polar β phase content and the diameter of electrospun PVDF nanofibers was investigated for the first time.Our experimental results show that the diameter of the electrospun PVDF nanofiber could be largely reduced and the content of polar β phase also become dominant immediately by just adding a little amount of DDAC.When the mass fraction of DDAC reached 4%,the content of polar β phase increased by about 39.1% compared with PVDF nanofibers without DDAC.Besides,the crystallinity of PVDF nanofibers also increased with the addition of DDAC.Based on the results,the possible mechanism of cooperative effect between electrospinning and DDAC on fiber diameter and formation of β phase in PVDF was discussed. 展开更多
关键词 Diameter crystalline crystallinity polar cooperative adding Polar ammonium alkyl attributed
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Cellular manufacturing layout on adding/removing machines 被引量:1
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作者 马汉武 张登凡 杨相 《Journal of Southeast University(English Edition)》 EI CAS 2010年第3期484-488,共5页
In order to rapidly respond to the complex and mutational market, a new facility layout plan based on cellular manufacturing is proposed, which gives consideration to high efficiency and flexibility. The plan designs ... In order to rapidly respond to the complex and mutational market, a new facility layout plan based on cellular manufacturing is proposed, which gives consideration to high efficiency and flexibility. The plan designs two phases of integrated cell layout, i.e., cell construction and cell system layout, on the condition of adding/removing machines. First, in view of the costs of logics and machine-relocation, the cell construction based on the alternative processing routes and intra-cell layout are integrated as a whole, which achieves cell formation, process planning and the intra-cell layout in a single step. Secondly, an approach of a continuous optimized multi-line layout for solving the cell system layout problem is proposed, which eliminates the coupling relationship from the machine-relocation and realizes an integrated design of the two phases of the cell layout. An application based on real factory data is optimally solved by the Matlab 7.0 software to validate and verify the models. 展开更多
关键词 cell layout adding/removing machine genetic algorithm
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Rapamycin as a preventive intervention for Alzheimer’s disease in APOE4 carriers:Targeting brain metabolic and vascular restoration
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作者 Ai-Ling Lin Chetan Aware 《Neural Regeneration Research》 2026年第2期685-686,共2页
Alzheimer’s disease(AD)is the most common form of dementia,affecting over 50 million people worldwide.This figure is projected to nearly double every 20 years,reaching 82 million by 2030 and 152 million by 2050(Alzhe... Alzheimer’s disease(AD)is the most common form of dementia,affecting over 50 million people worldwide.This figure is projected to nearly double every 20 years,reaching 82 million by 2030 and 152 million by 2050(Alzheimer’s Disease International).The apolipoproteinε4(APOE4)allele is the strongest genetic risk factor for late-onset AD(after age 65 years).Apolipoprotein E,a lipid transporter,exists in three variants:ε2,ε3,andε4.APOEε2(APOE2)is protective against AD,APOEε3(APOE3)is neutral,while APOE4 significantly increases the risk.Individuals with one copy of APOE4 have a 4-fold greater risk of developing AD,and those with two copies face an 8-fold risk compared to non-carriers.Even in cognitively normal individuals,APOE4 carriers exhibit brain metabolic and vascular deficits decades before amyloid-beta(Aβ)plaques and neurofibrillary tau tangles emerge-the hallmark pathologies of AD(Reiman et al.,2001,2005;Thambisetty et al.,2010).Notably,studies have demonstrated reduced glucose uptake,or hypometabolism,in brain regions vulnerable to AD in asymptomatic middle-aged APOE4 carriers,long before clinical symptoms arise(Reiman et al.,2001,2005). 展开更多
关键词 lipid transporterexists Dementia alzheimer s disease ad RAPAMYCIN Brain metabolic Vascular restoration Amyloid beta plaques APOE
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Astrocyte glycolysis in Alzheimer’s disease:When the stars burn out
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作者 Simon M.Bell Heather Mortiboys 《Neural Regeneration Research》 2026年第3期1130-1131,共2页
Alzheimer’s disease(AD)is the most common form of dementia characterized pathologically by the deposition of amyloid plaques and hyperphosphorylated tau containing neurofibrillary tangles.The disease presents clinica... Alzheimer’s disease(AD)is the most common form of dementia characterized pathologically by the deposition of amyloid plaques and hyperphosphorylated tau containing neurofibrillary tangles.The disease presents clinically with progressive memory loss and disruption of cognitive function.Currently,there is no cure for AD;recent advances in the therapeutics aimed at clearing the amyloid protein from the brain have led to potential disease stabilization,however,this does not prevent eventual disease progression(Cummings et al.,2024). 展开更多
关键词 hyperphosphorylated tau containing neurofibrillary tanglesthe memory loss alzheimer s disease ad Alzheimers disease ASTROCYTE GLYCOLYSIS amyloid protein amyloid plaques
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Utilizing Single-cell and Spatial RNA-seq databasE for Alzheimer’s Disease(ssREAD)in hypothesis-driven queries
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作者 Diana Acosta Cankun Wang +1 位作者 Qin Ma Hongjun Fu 《Neural Regeneration Research》 2026年第2期677-678,共2页
Alzheimer’s disease(AD)is the most common form of dementia.In addition to the lack of effective treatments,there are limitations in diagnostic capabilities.The complexity of AD itself,together with a variety of other... Alzheimer’s disease(AD)is the most common form of dementia.In addition to the lack of effective treatments,there are limitations in diagnostic capabilities.The complexity of AD itself,together with a variety of other diseases often observed in a patient’s history in addition to their AD diagnosis,make deciphering the molecular mechanisms that underlie AD,even more important.Large datasets of single-cell RNA sequencing,single-nucleus RNA-sequencing(snRNA-seq),and spatial transcriptomics(ST)have become essential in guiding and supporting new investigations into the cellular and regional susceptibility of AD.However,with unique technology,software,and larger databases emerging;a lack of integration of these data can contribute to ineffective use of valuable knowledge.Importantly,there was no specialized database that concentrates on ST in AD that offers comprehensive differential analyses under various conditions,such as sex-specific,region-specific,and comparisons between AD and control groups until the new Single-cell and Spatial RNA-seq databasE for Alzheimer’s Disease(ssREAD)database(Wang et al.,2024)was introduced to meet the scientific community’s growing demand for comprehensive,integrated,and accessible data analysis. 展开更多
关键词 sex specific alzheimer s disease ad deciphering molecular mechanisms spatial transcriptomics ssread spatial transcriptomics st Alzheimers disease single cell RNA seq
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Biomarkers for synaptic dysfunction in Alzheimer’s disease
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作者 Ruiqing Ni 《Neural Regeneration Research》 2026年第2期683-684,共2页
Alzheimer’s disease(AD)is the most common cause of dementia,characterized by progressive cognitive decline,and affects over 55 million people worldwide.AD is pathological featured by the aberrant accumulation of amyl... Alzheimer’s disease(AD)is the most common cause of dementia,characterized by progressive cognitive decline,and affects over 55 million people worldwide.AD is pathological featured by the aberrant accumulation of amyloid-βplaques,neurofibrillary tangles formed by hyperphosphorylated tau,synaptic loss,and dysfunction of neurotransmitter systems.Evidence from in vivo and autopsy studies has consistently shown that synaptic dysfunction and loss are strongly correlated with cognitive decline in AD,particularly in brain regions such as the hippocampus and cortex,which are critical for memory formation and processing.This perspective highlights recent histopathological findings related to synaptic dysfunction in AD,advancements in the development of imaging and fluid-based biomarkers for synaptic loss,and future studies. 展开更多
关键词 vivo autopsy studies synaptic dysfunction loss alzheimer s disease ad amyloid plaques cognitive declineand Alzheimers disease dysfunction neurotransmitter systemsevidence synaptic dysfunction
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光之庭 卡法萨巴TEL AD办公室
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作者 Eran Binderman Anastasiya Kotler +2 位作者 Ilya Kotler Oded Smadar(摄影) 小麦(编译) 《室内设计与装修》 2026年第1期36-39,共4页
Tel Ad办公空间坐落于以色列卡法萨巴一栋翻新建筑内。因自然采光条件有限,设计团队引入中央人工照明中庭,重塑空间流线,并通过材料运用,明确空间界定与功能分区。该中庭既是空间锚点,亦是氛围焦点。鉴于建筑进深较大,难以持续获取自然... Tel Ad办公空间坐落于以色列卡法萨巴一栋翻新建筑内。因自然采光条件有限,设计团队引入中央人工照明中庭,重塑空间流线,并通过材料运用,明确空间界定与功能分区。该中庭既是空间锚点,亦是氛围焦点。鉴于建筑进深较大,难以持续获取自然光线,中庭采用全光谱农业照明系统,以确保绿植全年茂盛生长。同时,空间流线也经重新设计,形成环绕绿色核心的环形路径,既确保了与绿植的持续视觉联系,又使各工作区域间的流线直观且流畅。除满足空间功能需求外,中庭在提升员工福祉与工作效率方面亦扮演关键角色:研究显示,相较于传统无窗办公环境,接触绿植及动态照明等自然元素,可有效降低压力、增强专注力并缓解视疲劳。室内统一采用水磨石地面、不锈钢装饰及天然木饰面,实现了整体空间的连贯性。 展开更多
关键词 Tel Ad办公空间 卡法萨巴
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Novel roles of DNA glycosylases in neurodegenerative diseases and aging
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作者 Vinod Tiwari Fivos Borbolis +2 位作者 Deborah L.Croteau Konstantinos Palikaras Vilhelm A.Bohr 《Neural Regeneration Research》 2026年第5期1991-1992,共2页
N umerous neurological disorders negatively impact the nervous system,either through loss of neurons or by disrupting the normal functioning of neural networks.These impairments manifest as cognitive defects,memory lo... N umerous neurological disorders negatively impact the nervous system,either through loss of neurons or by disrupting the normal functioning of neural networks.These impairments manifest as cognitive defects,memory loss,behavioral abnormalities,and motor dysfunctions.Decades of research have significantly advanced our understanding of the pathophysiology underlying neurodegene rative diseases,including Alzheimer's disease(AD),Parkinson's disease,amyotrophic lateral sclerosis,and others. 展开更多
关键词 alzheimers disease ad parkinsons diseaseamyotrophic lateral sclerosisand cognitive defects neurological disorders cognitive defectsmemory neurodegenerative diseases neurodegene rative diseasesincluding DNA glycosylases motor dysfunctionsdecades
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ADS⁃B数据在空管自动化系统中的处理方法分析
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作者 陈莹玥 《信息记录材料》 2026年第1期83-85,104,共4页
针对空管自动化系统中广播式自动相关监视(ADS⁃B)技术存在的数据处理效率低、准确性不足和实时性差的问题,本研究提出了一套完整的ADS⁃B数据处理技术方案。通过分析ADS⁃B技术的原理和数据组成特点,建立了包含数据采集预处理、传输存储... 针对空管自动化系统中广播式自动相关监视(ADS⁃B)技术存在的数据处理效率低、准确性不足和实时性差的问题,本研究提出了一套完整的ADS⁃B数据处理技术方案。通过分析ADS⁃B技术的原理和数据组成特点,建立了包含数据采集预处理、传输存储、融合校验的完整处理体系,并在航班跟踪监控、冲突检测告警、空域管理优化、飞行性能分析等方面进行了深入应用研究。结果表明:该处理方法能够有效提高空管自动化系统的监视精度和运行效率,解决了数据准确性与完整性、安全性与隐私保护、处理效率与实时性等关键技术挑战。 展开更多
关键词 广播式自动相关监视(ADS⁃B) 空管自动化系统 数据处理 监视技术 空中交通管理
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Dysregulated insulin signaling and inflammation contribute to the pathogenesis of Alzheimer’s disease:From animal models to human cells
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作者 Marcus Elo Rytter Cecilie Amalie Brøgger Svane +1 位作者 Joachim Størling Wenqiang Chen 《Neural Regeneration Research》 2026年第3期1126-1127,共2页
The shared links between Alzheimer’s disease and type 2 diabetes mellitus:Alzheimer’s disease(AD)and type 2 diabetes mellitus(T2DM)are two prevalent conditions that come with substantial daily struggles.Emerging evi... The shared links between Alzheimer’s disease and type 2 diabetes mellitus:Alzheimer’s disease(AD)and type 2 diabetes mellitus(T2DM)are two prevalent conditions that come with substantial daily struggles.Emerging evidence highlights that these diseases share similar pathophysiological features,including insulin resistance and chronic inflammation,which contribute to their rapid progression(Chen et al.,2022).Insulin resistance,a hallmark of T2DM,has been suggested to exacerbate neurodegeneration in AD.Similarly,chronic low-grade inflammation in T2DM parallels with neuroinflammation,which is observed in AD,suggesting overlapping pathophysiological mechanisms in T2DM and AD. 展开更多
关键词 alzheimer s disease chronic inflammationwhich type diabetes mellitus alzheimer s disease ad INFLAMMATION exacerbate neurodegeneration Alzheimers disease insulin resistance type diabetes mellitus t dm
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Study on the Optimum Moisture Amount Added to Brown Rice once during the Wet Conditioning 被引量:8
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作者 BAI Shi-gang JIA Fu-guo NAN Jing-fu 《Journal of Northeast Agricultural University(English Edition)》 CAS 2005年第2期137-140,共4页
In the experiment, the brown rice whose moisture content was 12.5% was used as raw material. The brown rice was grouped, then moisturized differently and milled. While milling, the energy consumption, the rate of brok... In the experiment, the brown rice whose moisture content was 12.5% was used as raw material. The brown rice was grouped, then moisturized differently and milled. While milling, the energy consumption, the rate of broken rice and the crack rate were tested. It is confirmed that the stress crack owing to the moisture added to the brown rice can be avoided when the moisture amount added once is limited to no more than 1.5%. It is also proved that the energy consumption can be reduced, the yielding rate of rice can be increased and that the quality of rice can be improved. 展开更多
关键词 brown rice rice milling moisture conditioning the optimum moisture amount added once
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Adding Sub-chain Method for Structural Synthesis of Planar Closed Kinematic Chains 被引量:2
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作者 DENG Zongquan YANG Fei TAO Jianguo 《Chinese Journal of Mechanical Engineering》 SCIE EI CAS CSCD 2012年第2期206-213,共8页
For at least the past five decades,structural synthesis has been used as a main means of finding better mechanisms with some predefined function.In structural synthesis,isomorphism identification is still a problem un... For at least the past five decades,structural synthesis has been used as a main means of finding better mechanisms with some predefined function.In structural synthesis,isomorphism identification is still a problem unsolved well,and to solve this problem is very significant to the design of new mechanisms.According to the given degree of freedom(DOF) and link connection property of planar closed chain mechanisms,vertex assortment is obtained.For solving the isomorphism problem,a method of the adding sub-chains is proposed with the detailed steps and algorithms in the synthesizing process.Employing this method,the identification code and formation code of every topological structure are achieved,therefore many isomorphic structures could be eliminated in time during structural synthesis by comparing those codes among different topological graphs,resulting in the improvement of synthesizing efficiency and accuracy,and the approach for eliminating rigid sub-chains in and after the synthesizing process is also presented.Some examples are given,including how to add sub-chains,how to detect simple rigid sub-chains and how to obtain identification codes and formulation codes et al.Using the adding sub-chain method,the relative information of some common topological graphs is given in the form of table.The comparison result is coincident with many literatures,so the correctness of the adding sub-chain method is convinced.This method will greatly improve the synthesizing efficiency and accuracy,and has a good potential for application. 展开更多
关键词 structural synthesis adding sub-chain method identification code formation code rigid sub-chains
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Improvement of the Conductivity of Silver Nanowire Film by Adding Silver Nano-Particles 被引量:1
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作者 沈奕 姚若河 《Chinese Physics Letters》 SCIE CAS CSCD 2016年第3期115-117,共3页
The change of conductivity and transparency of silver nanowire (AgNW) films by adding silver nano-particles (AgNPs) onto their surface is studied. The results show that the conductivity of the AgNW film is greatly... The change of conductivity and transparency of silver nanowire (AgNW) films by adding silver nano-particles (AgNPs) onto their surface is studied. The results show that the conductivity of the AgNW film is greatly improved with its sheet resistance reduced about 78. 7% to 51.9Ω/sq, and there is no obvious reduction of the transmittance. Further studies show that there is a self-assembling process pushing the AgNPs to concentrate at the intersecting points between AgNWs to weld them, which would reduce the intersection resistance between the AgNWs. This self-assembling behavior is led by the surface interactivities among the dispersing liquid of AgNPs, the surface of the substrate and AgNWs when the dispersing liquid is drying. 展开更多
关键词 of on is it by Improvement of the Conductivity of Silver Nanowire Film by adding Silver Nano-Particles were
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Scaling Properties of the Period-Adding Sequences in a Multiple Devil’s Staircase
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作者 WU Cai-yun QU Shi-xian +1 位作者 WU Shun-guang HE Da-ren 《Chinese Physics Letters》 SCIE CAS CSCD 1998年第4期246-248,共3页
In this letter the scaling properties of the period-adding sequences in a so-called“multiple Devil’s staircase”are reported.It is certified both analytically and numerically that the width of the i-th phase-locked ... In this letter the scaling properties of the period-adding sequences in a so-called“multiple Devil’s staircase”are reported.It is certified both analytically and numerically that the width of the i-th phase-locked plateau in a sequence scales as In|Δe(i)|∝i,and the position of the plateau scales as In|e_(∞)-e_(i)|∝i.These properties are qualitatively different from those of the period-adding sequences in conventional Devil’s staircases. 展开更多
关键词 adding LETTER SEQUENCES
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THE PERIOD-ADDING PHENOMENA IN A TWO-DIMENSIONAL MAPPING WITH THREE PARAMETERS
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作者 NI Wansun 《Chinese Physics Letters》 SCIE CAS 1986年第12期573-576,共4页
The period-adding phenomena in a two dimensional mapping with three parameters have been discussed.It has been found that the period-doubling bifurcations do not appear.
关键词 doubling adding BIFURCATIONS
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Wheat Generation Adding in Xundian County of Yunnan Province in Summer
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作者 Kong Zhi-you Liu Ye-ju Qin Peng 《Journal of Northeast Agricultural University(English Edition)》 CAS 2014年第4期1-9,共9页
Local climate conditions and sowing time are very important to the vernalization and summer reproduction of the wheat. Xundian County is located in Yunnan Province of China, at latitude 25.56° north and longitude... Local climate conditions and sowing time are very important to the vernalization and summer reproduction of the wheat. Xundian County is located in Yunnan Province of China, at latitude 25.56° north and longitude 103.25° east. Xundian County is situated 1 873 m above sea level, and is conducive for the summer reproduction of the wheat. To investigate the optimal sowing time, 11 spring wheat cultivars and one semi-winter wheat cultivar were sown 10 times at an interval of fi ve days from May 26, 2012, and the strong winter wheat Suyin 10 was treated in a vernalization room at 2℃ with different concentrations of the gibberellin and 5-azacytidine. The results showed that Suyin 10 should be vernalized at 2℃ for 30 days in summer, and the growth periods of strong winter wheat plants could been shortened if treated with a specifi c concentration of the gibberellin and 5-azacytidine at a low temperature. The growth period of the spring wheat in summer reproduction was delayed, and their agronomic traits gradually decreased with the passage of the sowing time. Thus, spring wheat should be sown at the earliest time possible for better yield. June 25 should be the latest date for summer reproduction of the wheat, but the semi-winter wheat cultivars in Xundian County should be added generation in summer after being treated at 2℃ for 10 days. Xundian County is a suitable location for summer reproduction of the wheat in China. 展开更多
关键词 WHEAT generation adding in summer vernalization method sowing time
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The Quality Specifications of Mischmetal Wire and Rod and the Method of Adding Rare Earth in Steel
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作者 鞠远峰 左生华 +3 位作者 林勤 刘爱生 王群 林东晖 《Journal of Rare Earths》 SCIE EI CAS CSCD 1994年第3期231-233,共3页
The quality of mischmetal wire and rod and the method of adding rare earth into steel are quite important for making high quality steel. This paper proposes a quality specification of wire and rod as well as related a... The quality of mischmetal wire and rod and the method of adding rare earth into steel are quite important for making high quality steel. This paper proposes a quality specification of wire and rod as well as related adding method. The paper also provides principles for selecting raw material and adding method. 展开更多
关键词 mischmetal wire and rod Quality specification adding method
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Properties of Nonlinear Transverse-Electric Waves in a Two-Core Optical Waveguide with a Nonlinear Cladding
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作者 MA Chun-sheng 《Chinese Physics Letters》 SCIE CAS CSCD 1998年第7期501-503,共3页
Expressions of dispersion relation and propagation power are presented for the nonlinear transverse-electric(TE)waves in a two-core optical waveguide with a nonlinear cladding.The properties of the nonlinear TE waves ... Expressions of dispersion relation and propagation power are presented for the nonlinear transverse-electric(TE)waves in a two-core optical waveguide with a nonlinear cladding.The properties of the nonlinear TE waves are analyzed.It is found that when the total core thickness and the distance between the two cores are sufficiently large,the power curves of the higher odd modes become very sharp in some narrow ranges of the effective refractive index,compared with those of the higher even modes. 展开更多
关键词 NONLINEAR NONLINEAR adding
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Testing the Adding up Condition in Demand Systems
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作者 Quirino Paris Francesco Caracciolo 《Open Journal of Statistics》 2017年第2期290-304,共15页
A test of the adding up condition in demand systems is crucial for determining whether a share format is admissible when the number of sample goods is smaller than the number of commodity choices available to consumer... A test of the adding up condition in demand systems is crucial for determining whether a share format is admissible when the number of sample goods is smaller than the number of commodity choices available to consumers. This test requires the estimation of a demand system in a quantity format. It cannot be performed when a demand system is specified in share format. The share specification of any demand system is like a straight jacket: once worn, it forces the error covariance matrix to be singular and the adding up condition to hold whether or not the data generating process warrants it. The empirical verification of the adding up hypothesis uses a five-commodity sample selected from the Canadian Family Expenditure Survey with 4847 observations. Three specifications are considered: AIDS (Almost Ideal Demand System), QUAIDS (Quadratic AIDS) and EASI (Exact Affine Stone Index). The hypothesis is rejected in all three cases with a high level of confidence. 展开更多
关键词 adding up DEMAND SYSTEMS Quantity FORMAT SHARE FORMAT
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Modulating the Lasing Performance of the Quantum Dot-Cavity System by Adding a Resonant Driving Field
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作者 秦利国 王琴 《Chinese Physics Letters》 SCIE CAS CSCD 2017年第1期115-119,共5页
We propose a new scheme on modulating the lasing performance of a quantum dot-cavity system. Compared to the conventional above-band pump, in our new scheme an additional resonant driving field is applied on the quant... We propose a new scheme on modulating the lasing performance of a quantum dot-cavity system. Compared to the conventional above-band pump, in our new scheme an additional resonant driving field is applied on the quantum dot-cavity system. By employing the master equation theory and the Jaynes-Cummings model, we are able to study the interesting phenomenon of the coupling system. To compare the different behaviors between using our new scheme and the conventional method,we carry out investigatioin for both the 'good system'and 'more realistic system', characterizing several important parameters, such as the cavity population, exciton population and the second-order correlation function at zero time delay. Through numerical simulations,we demonstrate that for both the good system and more realistic system, their lasing regimes can be displaced into other regimes in the presence of a resonant driving field. 展开更多
关键词 Modulating the Lasing Performance of the Quantum Dot-Cavity System by adding a Resonant Driving Field
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