通过超高效液相色谱串联四极杆飞行时间质谱技术(UPLC-Q-TOF/MS^(E))对肝豆扶木汤的化学成分进行分析鉴定;采用ZORBAX RRHD Eclipse Plus C_(18)色谱柱(2.1 mm×100 mm,1.8μm),以0.1%甲酸水-乙腈为流动相进行梯度洗脱,流速为0.2 m ...通过超高效液相色谱串联四极杆飞行时间质谱技术(UPLC-Q-TOF/MS^(E))对肝豆扶木汤的化学成分进行分析鉴定;采用ZORBAX RRHD Eclipse Plus C_(18)色谱柱(2.1 mm×100 mm,1.8μm),以0.1%甲酸水-乙腈为流动相进行梯度洗脱,流速为0.2 m L·min^(-1),柱温35℃。质谱分析采用电喷雾电离源(ESI)的方式,在正、负离子模式下,通过UPLC-Q-TOF/MS^(E)分析鉴定肝豆扶木汤的化学成分。共鉴定出102种化合物,其中黄酮类成分26个,萜类成分22个,皂苷类成分19个,苯丙素类成分10个和其他类成分25个。本研究所建立的定性分析方法能快速、高效地对肝豆扶木汤的化学成分进行分析鉴定,为肝豆扶木汤的质量评价和临床应用提供了科学依据。展开更多
The human factor is the most important cause of road accidents. Investigating the drivers’ mental patterns can lead to a better understanding of the factors that affect drivers to make a mistake and thus increase the...The human factor is the most important cause of road accidents. Investigating the drivers’ mental patterns can lead to a better understanding of the factors that affect drivers to make a mistake and thus increase the likelihood of an accident. In this study, mental patterns of drivers as a human characteristic are determined through a questionnaire survey. To do this, 166 participants (18 - 65 years) were asked to express their opinion on the possible effect of 25 factors on the occurrence of accidents. These factors were selected through the investigation of the accident database during the last three years in different areas of the case study. To analyze the data extracted from the survey, Q-methodology was used. The results of the factor analysis showed that there are 5 mental patterns among the participants. Based on the driver’s opinion, human factors and road conditions were the most and least influential accident-generating items, respectively. The most significant reason for accidents determined by drivers was human errors including 1) unauthorized overtaking, 2) unauthorized speed, 3) driver distractions (such as cell phone), and 4) driver physical disability (such as visual impairment). Moreover, the failure of the vehicle was mostly reported as another influential contributor to accidents. It is worth mentioning that the results of this study can be used to minimize accidents resulted from drivers’ behavioral errors by suggesting strategies for enhancing their performance through new manuals which is a step towards a safer road.展开更多
文摘通过超高效液相色谱串联四极杆飞行时间质谱技术(UPLC-Q-TOF/MS^(E))对肝豆扶木汤的化学成分进行分析鉴定;采用ZORBAX RRHD Eclipse Plus C_(18)色谱柱(2.1 mm×100 mm,1.8μm),以0.1%甲酸水-乙腈为流动相进行梯度洗脱,流速为0.2 m L·min^(-1),柱温35℃。质谱分析采用电喷雾电离源(ESI)的方式,在正、负离子模式下,通过UPLC-Q-TOF/MS^(E)分析鉴定肝豆扶木汤的化学成分。共鉴定出102种化合物,其中黄酮类成分26个,萜类成分22个,皂苷类成分19个,苯丙素类成分10个和其他类成分25个。本研究所建立的定性分析方法能快速、高效地对肝豆扶木汤的化学成分进行分析鉴定,为肝豆扶木汤的质量评价和临床应用提供了科学依据。
文摘The human factor is the most important cause of road accidents. Investigating the drivers’ mental patterns can lead to a better understanding of the factors that affect drivers to make a mistake and thus increase the likelihood of an accident. In this study, mental patterns of drivers as a human characteristic are determined through a questionnaire survey. To do this, 166 participants (18 - 65 years) were asked to express their opinion on the possible effect of 25 factors on the occurrence of accidents. These factors were selected through the investigation of the accident database during the last three years in different areas of the case study. To analyze the data extracted from the survey, Q-methodology was used. The results of the factor analysis showed that there are 5 mental patterns among the participants. Based on the driver’s opinion, human factors and road conditions were the most and least influential accident-generating items, respectively. The most significant reason for accidents determined by drivers was human errors including 1) unauthorized overtaking, 2) unauthorized speed, 3) driver distractions (such as cell phone), and 4) driver physical disability (such as visual impairment). Moreover, the failure of the vehicle was mostly reported as another influential contributor to accidents. It is worth mentioning that the results of this study can be used to minimize accidents resulted from drivers’ behavioral errors by suggesting strategies for enhancing their performance through new manuals which is a step towards a safer road.
